Tesi sul tema "Cancers du tube digestif"
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Diebold, Valérie. "Amiante et cancers digestifs : discussion à propos d'une observation : revue de la littérature". Université Louis Pasteur (Strasbourg) (1971-2008), 1992. http://www.theses.fr/1992STR1M024.
Testo completoAdam, Frédéric. "Les lasers medicaux : application a la photochimiotherapie des cancers, a mediation porphyrinique, en gastro-enterologie". Nantes, 1989. http://www.theses.fr/1989NANT002M.
Testo completoGrellet, Pierre. "Les tumeurs du tube digestif dans les Pyrénées Orientales : étude statistique de 1984 à 1990". Montpellier 1, 1992. http://www.theses.fr/1992MON11038.
Testo completoAbdulla, Aboobakar. "Rôle de la chirurgie dans la prévention des cancers du tube digestif, de l'utérus et des mélanomes malins". Montpellier 1, 1990. http://www.theses.fr/1990MON11223.
Testo completoLafeuille, Pierre. "Prise en charge diagnostique et thérapeutique des lésions superficielles du tube digestif assistée par les techniques numériques". Electronic Thesis or Diss., Lyon 1, 2024. http://www.theses.fr/2024LYO10292.
Testo completoDigestive cancers are among the most common cancers, with a high mortality rate. They most often develop from a benign lesion that slowly evolves and eventually becomes cancerous. Organized screening by endoscopy increases the chances of cure, thanks to early detection and treatment. With recent optical advances in endoscopic imaging, a wide variety of lesions can be visualized during colonoscopic examinations. We first demonstrated that, once detected, colorectal lesions need to be characterized in order to predict histology in real time during endoscopy and choose the best therapeutic option for each lesion. Biopsies (targeted or not) are unnecessary and may make subsequent resection more difficult. The many existing classifications have their limitations, however, and we have therefore merged the criteria of all the usual classifications into the CONECCT classification, which in a prospective evaluation demonstrated its good diagnostic performance, enabling appropriate treatment choices to be made for lesions. We then sought to develop the initial CONECCT classification, by adding lesions with a focal zone of deep invasion, showing that diagnostic submucosal dissection is feasible for these lesions, and by adding colonic submucosal lesions, showing that as most are not malignant, they do not warrant advanced endoscopic resection but could benefit from a step-up strategy starting with simple histological sampling with advanced resection for the rare malignant lesions in a second stage. As lesion degeneration is not homogeneous, we sought to improve detection of areas of interest by showing that an area stained green in virtual chromoendoscopy, or green sign, could be associated with a more pejorative lesion histology. All the more so as we have described the difficulty presented by AI systems in detecting flat lesions such as sessile serrated lesions and non-granular laterally spreading tumors. As the characterization of colorectal lesions is essential but very difficult, we then sought to improve the characterization training of French-speaking gastroenterologists, via a working group on a social network, featuring educational videos dedicated to characterization. However, passive use of the group, with a very low degree of user interaction, failed to show any progression among residents over one year. Finally, we have developed a free application on computer and smartphone, enabling collaborative characterization by a trio of experts of 20 colorectal lesions published by 12 gastroenterologists
Lafond, Michel. "Données récentes des traitements chirurgicaux et adjuvants du cancer du rectum et bilan : à propos de 20 cas opérés en 1984 et 1985". Clermont-Ferrand 1, 1987. http://www.theses.fr/1987CLF13024.
Testo completoDoutriaux, Deville Béatrice. "Traitements palliatifs du cancer de l'oesophage". Paris 7, 1989. http://www.theses.fr/1989PA07B088.
Testo completoPeyrou, Christophe. "Les malt lymphomes primitifs du tube digestif : aspects conceptuels, étiopathogéniques, anatomocliniques et thérapeutiques à propos de 3 observations et revue de la littérature". Bordeaux 2, 1995. http://www.theses.fr/1995BOR2M163.
Testo completoDucarouge, Benjamin. "Régulation des systèmes d'adhérence cellulaire par le CRF2 : un effecteur du stress dans le tube digestif". Phd thesis, Université de Grenoble, 2012. http://tel.archives-ouvertes.fr/tel-00767103.
Testo completoDELMOTTE, JEAN. "La pharyngo-laryngectomie totale circulaire avec reconstruction par visceroplastie". Lille 2, 1988. http://www.theses.fr/1988LIL2M176.
Testo completoBaydoun, Martha. "Développement d’un modèle de culture tridimensionnelle à partir d’explants entériques pour l’étude de la cryptosporidiose". Thesis, Lille, 2018. http://www.theses.fr/2018LIL1I003.
Testo completoAlmost 20% of cancers are due to a viral, bacterial or parasitic infection. For instance, Cryptosporidium parvum (C. parvum) was found to induce the development of an invasive digestive adenocarcinomas in an experimental model of SCID mice.However, the understanding of the pathogenesis of Cryptosporidium has been limited by the lack of a long-term culture system. It is therefore essential to improve the in vitro culture systems by trying to mimic the in vivo conditions. Firstly, the association between Cryptosporidium infection and cancer development was investigated through an epidemiological study among cohorts of Lebanese patients with or without recent diagnosis of digestive cancer before any treatment. A high rate of Cryptosporidium was detected in biopsies from Lebanese patients with digestive neoplasia/adenocarcinoma. These results showed that Cryptosporidium is associated with human colon cancer being maybe a potential etiological agent of this disease. In the second part, a three dimensional (3D) Cryptosporidium culture model was developed from adult murine colon. This system allowed the reproduction of neoplasic lesions at 27 days post-infection, providing new evidence of the role of the parasite in the induction of carcinogenesis. This is the first description of a low-grade intraepithelial neoplasia induction after parasite infection in a 3D culture. Finally, in order to automatize the culture, a microfluidics device for explant culture was designed. An explant culture was maintained for almost 8 days using this microfluidic device. To our knowledge, this is the first description of a gut tissue culture on a microfluidic device that was viable for 8 days
Boruchowicz, Arnaud. "Sarcoidose et tube digestif". Lille 2, 1993. http://www.theses.fr/1993LIL2M136.
Testo completoRougelin-Clapasson, Christine. "Vascularites et tube digestif". Montpellier 1, 1990. http://www.theses.fr/1990MON11291.
Testo completoSavoye-Collet, Céline. "Imagerie fonctionnelle du tube digestif". Rouen, 2006. http://www.theses.fr/2006ROUE04NR.
Testo completoDumonceau, Jean-Marc. "Mycobactéries et maladies inflammatoires du tube digestif". Doctoral thesis, Universite Libre de Bruxelles, 1997. http://hdl.handle.net/2013/ULB-DIPOT:oai:dipot.ulb.ac.be:2013/212222.
Testo completoMONNIER, BEAUVIR LAURENCE. "Hyperplasie lymphoide du tube digestif chez l'enfant". Lyon 1, 1993. http://www.theses.fr/1993LYO1M018.
Testo completoLéger, Philippe. "Tumeurs mésenchymateuses du tube digestif à propos de 51 cas". Montpellier 1, 1996. http://www.theses.fr/1996MON11146.
Testo completoLecomte, Claire Caillon Jocelyne. "Epidémiologie bactérienne du tube digestif en période néonatale". [S.l.] : [s.n.], 2006. http://theses.univ-nantes.fr/thesemed/PHlecomte.pdf.
Testo completoStroesser, Joséphine Caillaux-Varin Gaëlle. "Description de la flore bactérienne digestive per-opératoire néonatale résultats intermédiaires /". [S.l.] : [s.n.], 2008. http://castore.univ-nantes.fr/castore/GetOAIRef?idDoc=35286.
Testo completoKhreiche, Antoine. "Aspects héréditaires des cancers digestifs familiaux". Montpellier 1, 1998. http://www.theses.fr/1998MON11050.
Testo completoTognarelli, Bruno. "Bilan d'extension des cancers digestifs : laparoscopie ou imagerie médicale ?" Montpellier 1, 1992. http://www.theses.fr/1992MON11156.
Testo completoORHOND, CELINE. "Angiodysplasies du tractus digestif : traitement par oestroprogestatifs". Aix-Marseille 2, 1994. http://www.theses.fr/1994AIX20186.
Testo completoLE, GUENEC YANN. "Photocoagulation laser per endoscopique des angiomes du tube digestif". Nantes, 1990. http://www.theses.fr/1990NANT056M.
Testo completoMERIGNARGUES, STEPHANE. "Manifestations cutaneo-muqueuses des maladies inflammatoires du tube digestif". Lille 2, 1989. http://www.theses.fr/1989LIL2M123.
Testo completoFLUCK, SANDRINE. "Monoxyde d'azote et tube digestive". Strasbourg 1, 1994. http://www.theses.fr/1994STR15051.
Testo completoMeunier, Patrick. "Physiopathologie des dysfonctionnements de la motricité du tube digestif terminal". Lyon 1, 1985. http://www.theses.fr/1985LYO1H056.
Testo completoFELICITE, NICOLE. "Chirurgie et lymphomes malins non hodgkiniens primitifs du tube digestif". Nice, 1991. http://www.theses.fr/1991NICE6006.
Testo completoSOBHANI, TRADJ. "Production et signification de paf-acether dans le tube digestif". Paris 7, 1992. http://www.theses.fr/1992PA077188.
Testo completoLepage, Côme. "Epidémiologie des cancers digestifs rares : incidence, tendances chronologiques, pronostic". Dijon, 2007. http://www.theses.fr/2007DIJOMU01.
Testo completoImportant changes have occurred in the epidemiology of rare digestive cancers. It is difficult to obtain unbiased data to study the epidemiology of those cancers. Population-based studies recording all cases in a well-defined population represent the only way to assess this disquieting situation. Thus the objective of this study was to examine trends in incidence prognosis and socio economical disparities to improve the epidemiological knowledge of these cancers. The prognosis in the general population is considerably worse than is often reported from small hospital case series. Early diagnosis is difficult: new therapeutic options appear to represent the best approach to improved prognosis. All cancers were characterised by a sharp increase of incidence over the past years, both by period and birth cohort, but the most important rise was for oesophageal adenocarcinoma. Etiological studies still necessary to understand the reasons of such a rise
Aubé, Christophe. "Evaluation de l'echo-endoscopie sectorielle electronique en pathologie digestive : resultats preliminaires d'une etude prospective". Angers, 1994. http://www.theses.fr/1994ANGE1000.
Testo completoDUROUS, ERIC. "L'angiodysplasie digestive : abord diagnostique et therapeutique ; a propos de 36 observations". Lyon 1, 1990. http://www.theses.fr/1990LYO1M267.
Testo completoGarin, Isabelle. "Tomodensitométrie du tube digestif sous-diaphragmatique de l'adulte : sous la forme d'un Kit d'enseignement". Bordeaux 2, 1990. http://www.theses.fr/1990BOR23029.
Testo completoBouhours, Danièle. "Les Glycolipides au cours du développement du tube digestif de rat". Lyon 1, 1985. http://www.theses.fr/1985LYO10024.
Testo completoTHOMAS, PASCAL. "Le traitement chirurgical des lymphomes malins non hodgkiniens du tube digestif". Lyon 1, 1994. http://www.theses.fr/1994LYO1M67B.
Testo completoHouache, Nadir. "Tube digestif, labre et glandes labrales des copépodes calanoïdes et cyclopoïdes". Aix-Marseille 3, 1997. http://www.theses.fr/1997AIX30057.
Testo completoTourniaire, Franck. "Stabilité, transport et métabolisme de microconstituants phénoliques dans le tube digestif". Aix-Marseille 2, 2006. http://www.theses.fr/2006AIX20689.
Testo completoPolyphenols are the most widely occuring microconstituent family of our diet. Animal studies as well as some epidemiological data show an inverse association between the high intake of some popyphenol classes and the incidence of evolutive diseases such as atherosclerosis and cancer. Biological effects of a molecule depend on its bioavailability, and polyphenol bioavailability remains obscure. In the present work, two determinant aspects of bioavailabilty have been investigated: 1) Stability during gastro-intestinal digestion. In vitro acellular studies have shown that polyphenol stability depends on their molecular structure. Moreover, it has been observed that polyphenols are able to protect other classes of dietary antioxidants (vitamin E and carotenoids) from oxidation in the upper digestive tract. These results could explain the of some supplementation studies. 2) Absorption and metabolism by enterocytes. Absorption studies across differentiated Caco-2/TC7 cells have been performed with two frequently dietary occurring molecules, vanillin and naringin. Data displayed that transport and metabolism mechanisms depend on the structure, and several metabolites have been identified. Weak absorption of naringin and extensive metabolism of vanillin by enterocytes are responsible of the poor intestinal absorption of these compounds. Taken together, these data could contribute to the elucidation of the in vivo biological effects of polyphenols
Weber, Jacques. "Etudes anatomo-physiologiques du contrôle nerveux extrinsèque du tube digestif chez l'homme". Aix-Marseille 3, 1990. http://www.theses.fr/1990AIX30036.
Testo completoRicard, Sylvie. "Tumeurs germinales primitives du système digestif : à propos d'un cas". Montpellier 1, 2001. http://www.theses.fr/2001MON11016.
Testo completoQUEROY-MALAMENAIDE, CHRISTOPHE. "Les duplications du tube digestif chez l'enfant : a propos de dix observations". Clermont-Ferrand 1, 1991. http://www.theses.fr/1991CLF13044.
Testo completoThirapathi-Appadu, Yogananda. "Le risque infectieux en endoscopie digestive : resultats d'une etude prospective concernant la gastroscopie et la coloscopie chez 74 patients". Nancy 1, 1990. http://www.theses.fr/1990NAN11216.
Testo completoBOYER, PIERRE-LUC. "L'endoscopie digestive haute chez les sujets de plus de 80 ans : a propos de 1473 cas". Angers, 1989. http://www.theses.fr/1989ANGE1031.
Testo completoKREBS, PATAT PATRICIA. "Les duplications digestives chez l'enfant a propos de sept observations". Reims, 1988. http://www.theses.fr/1988REIMM031.
Testo completoRIXAIN, DIDIER. "Apport de la fibroscopie oeso-gastro-duodenale dans un service d'urgence". Nantes, 1992. http://www.theses.fr/1992NANT130M.
Testo completoMazet, Bruno. "Modulation de la transmission synaptique au niveau du plexus coeliaque par les afférences gastro-intestinales : rôle du plexus coeliaque dans l'organisation d'un réflexe gastro-duodénal inhibiteur". Aix-Marseille 3, 1992. http://www.theses.fr/1992AIX30007.
Testo completoBagnol, Didier. "Organisation des voies nerveuses enképhalinergiques extrinsèques et intrinsèques, impliquées dans la commande motrice du tractus digestif". Aix-Marseille 3, 1994. http://www.theses.fr/1994AIX30015.
Testo completoAUVIGNE, CHRISTINE. "Dilatation du tube digestif au cours de la neurofibromatose de recklinghausen : revue de la litterature a propos d'un cas". Nantes, 1990. http://www.theses.fr/1990NANT013M.
Testo completoDOLO, MAISSELEM. "Les manifestations digestives du purpura rhumatoide de l'adulte : a propos d'une observation". Aix-Marseille 2, 1988. http://www.theses.fr/1988AIX20117.
Testo completoJACOB, MEGE PASCALE. "Mastocytose cutanee avec atteinte digestive : a propos d'un cas". Limoges, 1988. http://www.theses.fr/1988LIMO0131.
Testo completoCARPENTIER, BLONDEL NATHALIE, e Denis Carpentier. "Endoscopies digestives hautes et basses chez le sujet age de 80 ans et plus (indications et resultats)". Amiens, 1988. http://www.theses.fr/1988AMIEM098.
Testo completoBIANCHI, DANIEL. "Manifestations digestives du sida : apports de l'endoscopie". Nice, 1991. http://www.theses.fr/1991NICE6004.
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