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Libri sul tema "Cancer cell microenvironment"

Autore: Grafiati

Pubblicato: 2 novembre 2024

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1

Prasad, Mayuri Sinha, Pranela Rameshwar e Cristian Pablo Pennisi. The Stem Cell Microenvironment and Its Role in Regenerative Medicine and Cancer Pathogenesis. New York: River Publishers, 2022. http://dx.doi.org/10.1201/9781003339779.

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2

Jamie, Goode, Chadwick Derek, Novartis Foundation e Symposium on the Tumour Microenvironment: Causes and Consequences of Hypoxia and Acidity (2000 : London, England), a cura di. The tumour microenvironment: Causes and consequences of hypoxia and acidity. Chichester: Wiley, 2001.

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3

Gianfranco, Fiorentini, Cogle Christopher R e SpringerLink (Online service), a cura di. Cancer Microenvironment and Therapeutic Implications: Tumor Pathophysiology Mechanisms and Therapeutic Strategies. Dordrecht: Springer Netherlands, 2009.

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4

Siemann, Dietmar W. Tumor Microenvironment. Wiley & Sons, Incorporated, John, 2011.

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5

Siemann, Dietmar W. Tumor Microenvironment. Wiley & Sons, Incorporated, John, 2011.

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6

Siemann, Dietmar W. Tumor Microenvironment. Wiley & Sons, Incorporated, John, 2010.

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7

Tumor microenvironment. Hoboken: Wiley, 2011.

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8

Physics of Cancer. Cambridge University Press, 2017.

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9

Zapperi, Stefano, e Caterina A. M. La Porta. Physics of Cancer. Cambridge University Press, 2017.

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10

Zapperi, Stefano, e Caterina A. M. La Porta. Physics of Cancer. Cambridge University Press, 2017.

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11

Rameshwar, Pranela, Cristian Pablo Pennisi e Mayuri Sinha Prasad. Stem Cell Microenvironment and Its Role in Regenerative Medicine and Cancer Pathogenesis. River Publishers, 2017.

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12

Rameshwar, Pranela, Cristian Pablo Pennisi e Mayuri Sinha Prasad. Stem Cell Microenvironment and Its Role in Regenerative Medicine and Cancer Pathogenesis. River Publishers, 2022.

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13

Rhim, Johng S., Anatoly Dritschilo e Richard Kremer. Human Cell Transformation: Advances in Cell Models for the Study of Cancer and Aging. Springer, 2019.

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14

Rhim, Johng S., Anatoly Dritschilo e Richard Kremer. Human Cell Transformation: Advances in Cell Models for the Study of Cancer and Aging. Springer International Publishing AG, 2020.

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15

Wennerberg, Erik, Andreas Lundqvist, Yumeng Mao e Dimitrios Mougiakakos. NK-Myeloid Cell Interactions in the Tumor Microenvironment: Implications for Cancer Immunotherapy. Frontier Media SA, 2021. http://dx.doi.org/10.3389/978-2-88971-271-7.

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16

Rameshwar, Pranela, Cristian Pablo Pennisi e Mayuri Sinha Prasad. Stem Cell Microenvironment and Its Role in Regenerative Medicine and Cancer Pathogenesis. River Publishers, 2022.

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17

Rameshwar, Pranela, Cristian Pablo Pennisi e Mayuri Sinha Prasad. Stem Cell Microenvironment and Its Role in Regenerative Medicine and Cancer Pathogenesis. River Publishers, 2022.

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18

Stem Cell Microenvironment and Its Role in Regenerative Medicine and Cancer Pathogenesis. River Publishers, 2017.

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19

Moerdler, Scott, e Xingxing Zang. PD-1/PDL-1 Inhibitors as Immunotherapy for Ovarian Cancer. Oxford University Press, 2018. http://dx.doi.org/10.1093/med/9780190248208.003.0010.

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Abstract (sommario):

Programmed death 1 (PD-1), a member of the B7-CD28 immunoglobulin superfamily, and its ligands PD-L1/PD-L2 inhibit T-cell activation. They also play a key role in the tumor microenvironment, allowing for cancer immune escape. PD-1 is induced on a variety of immune cells, including tumor-infiltrating lymphocytes (TILs), while PD-L1 is found on many types of solid tumors including ovarian cancer and some TILs. The use of immunocheckpoint inhibitors like anti-PD-1 and anti-PD-L1 therapies has been shown to reactivate the immune system to attack tumor cells. Ovarian cancers have been shown to be responsive to anti-PD-1 and anti-PD-L1 therapies, though immunocheckpoint inhibitors are not enough. Current research is evaluating combination therapies to improve response rates.

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20

The Tumour Microenvironment - No. 240: Causes and Consequences of Hypoxia and Acidity (Novartis Foundation Symposia). Wiley, 2001.

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21

Siemann, Dietmar W. Tumor Microenvironment. Wiley & Sons, Incorporated, John, 2010.

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22

Bagley, Rebecca G. Tumor Microenvironment. Springer, 2010.

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23

Bagley, Rebecca G. The Tumor Microenvironment. Humana, 2012.

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24

Reader, Jocelyn, Sarah Lynam, Amy Harper, Gautam Rao, Maya Matheny e Dana M. Roque. Ovarian Tumor Microenvironment and Innate Immune Recognition. Oxford University Press, 2018. http://dx.doi.org/10.1093/med/9780190248208.003.0004.

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Ovarian adenocarcinoma is typified by detection at late stages with dissemination of cancer cells into the peritoneal cavity and frequent acquisition of chemoresistance. A number of studies show the importance of the tumor microenvironment and innate immune recognition in tumor progression. Ovarian cancer cells can regulate the composition of their stroma to promote the formation of ascitic fluid rich in cytokines and bioactive lipids such as PGE2, and to stimulate the differentiation of stromal cells into a pro-tumoral phenotype. In response, cancer-associated fibroblasts, cancer-associated mesenchymal stem cells, tumor-associated macrophages, and other peritoneal cells can act through direct and indirect mechanisms to regulate tumor growth, chemoresistance via alteration of class III β‎ tubulin, angiogenesis and dissemination. This chapter deciphers the current knowledge about the role of stromal cells, associated secreted factors, and the immune system on tumor progression. This suggests that targeting the microenvironment holds great potential to improve the prognosis of patients with ovarian adenocarcinoma.

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25

Josephs, Debra H., Heather J. Bax, Giulia Pellizzari, James F. Spicer, Ana Montes e Sophia N. Karagiannis. Antibody Therapeutics for Ovarian Carcinoma and Translation to the Clinic. Oxford University Press, 2018. http://dx.doi.org/10.1093/med/9780190248208.003.0001.

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Despite improvements over the past decade in the treatment of ovarian cancer, many patients are at risk of recurrent disease and emerging drug resistance. The increased selectivity and reduced toxicity of molecularly targeted anti-cancer agents renders them attractive for development in ovarian cancer, and monoclonal antibodies targeting ovarian cancer-specific tumor antigens represent the largest such group investigated in this clinical setting. This chapter describes examples of monoclonal antibodies clinically evaluated for efficacy in ovarian cancer. These agents recognize molecular targets expressed on tumors or within tumor microenvironments that may be essential for tumor cell survival and proliferation. Recently, antibodies targeting checkpoint molecules on immune cells have shown efficacy in modulating anti-tumor immunity, and applications in ovarian carcinomas are evaluated. The chapter focuses on therapeutic agents’ attributes on targeting key cancer growth and progression pathways, and propensity to engender effector functions by activating immune effector cells in tumors and the circulation.

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26

Li, Yongsheng, e Bo Zhu, a cura di. Metabolism of Cancer Cells and Immune Cells in the Tumor Microenvironment. Frontiers Media SA, 2019. http://dx.doi.org/10.3389/978-2-88945-785-4.

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27

Gunduz, Mehmet, a cura di. Breast Cancer - Focusing Tumor Microenvironment, Stem cells and Metastasis. InTech, 2011. http://dx.doi.org/10.5772/1747.

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28

Breast Cancer - Focusing Tumor Microenvironment, Stem cells and Metastasis. InTech, 2011.

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29

Baronzio, Gianfranco, Giammaria Fiorentini e Christopher R. Cogle. Cancer Microenvironment and Therapeutic Implications: Tumor Pathophysiology Mechanisms and Therapeutic Strategies. Springer, 2010.

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30

Yefenof, Eitan. Innate and Adaptive Immunity in the Tumor Microenvironment. Springer, 2010.

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