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Letteratura scientifica selezionata sul tema "Cancer, bibliography"

Autore: Grafiati

Pubblicato: 29 luglio 2024

Ultima modifica: 30 luglio 2024

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Articoli di riviste sul tema "Cancer, bibliography"

1

Adcock, Joyce. "BREAST CANCER BIBLIOGRAPHY". Rehabilitation Oncology 4, n. 2 (1986): 14. http://dx.doi.org/10.1097/01893697-198604020-00017.

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Frymark, Sue L. "Bibliography: Cancer Rehabilitation". Rehabilitation Oncology 18, n. 3 (2000): 29–30. http://dx.doi.org/10.1097/01893697-200018030-00015.

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Rabinowitz, Barbara. "Selected Bibliography—Cancer and Sexuality". Rehabilitation Oncology 9, n. 3 (novembre 1991): 15–16. http://dx.doi.org/10.1097/01893697-199109030-00011.

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&NA;. "Bibliography Current World Literature". Current Opinion in Oncology 9, n. 2 (marzo 1997): B41—B46. http://dx.doi.org/10.1097/00001622-199703000-00017.

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&NA;. "Bibliography Current World Literature". Current Opinion in Oncology 9, n. 2 (marzo 1997): B47—B55. http://dx.doi.org/10.1097/00001622-199703000-00018.

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&NA;. "Bibliography Current World Literature". Current Opinion in Oncology 9, n. 2 (marzo 1997): B56—B64. http://dx.doi.org/10.1097/00001622-199703000-00019.

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&NA;. "Bibliography Current World Literature". Current Opinion in Oncology 9, n. 5 (settembre 1997): B135—B138. http://dx.doi.org/10.1097/00001622-199709050-00018.

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&NA;. "Bibliography Current World Literature". Current Opinion in Oncology 11, n. 1 (gennaio 1999): B1. http://dx.doi.org/10.1097/00001622-199901000-00016.

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&NA;. "Bibliography Current World Literature". Current Opinion in Oncology 11, n. 2 (marzo 1999): B67. http://dx.doi.org/10.1097/00001622-199903000-00013.

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&NA;. "Bibliography Current World Literature". Current Opinion in Oncology 11, n. 3 (maggio 1999): B103. http://dx.doi.org/10.1097/00001622-199905000-00018.

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Più fonti

Tesi sul tema "Cancer, bibliography"

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梁國慶. "中醫藥治療癌症骨轉移的文獻研究". HKBU Institutional Repository, 2009. http://repository.hkbu.edu.hk/etd_ra/1044.

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金鑫. "骨轉移癌的中醫藥治療文獻研究". HKBU Institutional Repository, 2012. http://repository.hkbu.edu.hk/etd_ra/1338.

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Ladeiras, Vera Maria Fernandes Bugalho. "Análises sanguíneas na detecção de cancro". Master's thesis, 2019. http://hdl.handle.net/10437/10128.

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Orientação: Marisa Nicolai
O cancro representa uma das principais ameaças para a nossa sociedade, tanto a nível económico, como em qualidade de vida. O diagnóstico precoce pode aumentar a probabilidade de cura e melhorar as condições de sobrevida. A detecção de cancro no sangue pode ser realizada através de biomarcadores tumorais. Hoje em dia, os principais marcadores utilizados ainda não apresentam a especificidade e a sensibilidade pretendidas. São raras as excepções em que são utilizados na practica oncológica. As biópsias líquidas vieram trazer um novo conceito para a área de oncologia. Consistem em técnicas não invasivas de detecção, e análise de biomarcadores genéticos, provenientes de células tumorais. Os principais biomarcadores estudados são: as células tumorais circulantes (CTC), ADN tumoral circulante (ctDNA) e os exossomas (EXO). Estes marcadores podem vir a ser uma solução para a detecção e diagnóstico de cancro, uma vez que permitem estudar a heterogeneidade temporal e espacial. Esta tese de mestrado é uma revisão bibliográfica que se vai focar na importância clínica destes testes clínicos na detecção do cancro, a biogénese e as características destes biomarcadores e as técnicas de isolamento utilizadas. Assim como os desafios e as expectativas para que possam ser implementadas durante a practica clínica.
Cancer is a major threat to our society, both economically and with respect to quality of life. Early diagnosis can increase the likelihood of cure and improve survival conditions. Blood cancer is detected by tumor biomarkers. Nowadays, the main markers used don`t have the desired specificity and sensitivity. The exceptions in which they are used in cancer practice are rare. Liquid biopsies have brought a new concept to the field of oncology. They consist of noninvasive detection techniques and analysis of genetic biomarkers from tumor cells. The main biomarkers studied are: circulating tumor cells (CTC), circulating tumor DNA (ctDNA) and exosomes (EXO). These markers may prove to be a solution for cancer detection and diagnosis, as they allow the study of temporal and spatial heterogeneity. This master's thesis is a bibliographical review that will focus on the clinical importance of these clinical tests in cancer detection, the biogenesis and characteristics of these biomarkers and on the isolation techniques used. As well as the challenges and expectations so that they can be implemented during clinical practice.

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Libri sul tema "Cancer, bibliography"

1

Kelly, Alison P. Breast cancer. Washington, D.C: Science Reference Section, Science, Technology and Business Division, Library of Congress, 2002.

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Kelly, Alison P. Breast cancer. Washington, D.C: Science Reference Section, Science, Technology and Business Division, Library of Congress, 2002.

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National Cancer Institute (U.S.). National Cancer Institute patient materials catalog: Living with cancer. Bethesda, Md: U.S. Dept. of Health and Human Services, Public Health Service, National Cancer Institute, 1986.

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National Cancer Institute (U.S.). National Cancer Institute patient materials catalog: Living with cancer. Bethesda, Md: U.S. Dept. of Health and Human Services, Public Health Service, National Cancer Institute, 1986.

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Olson, James Stuart. The history of cancer: An annotated bibliography. New York: Greenwood Press, 1989.

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National Cancer Institute (U.S.). Cancer prevention catalog. Bethesda, Md: The Institute, 1985.

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National Cancer Institute (U.S.). Cancer prevention catalog. Bethesda, Md: The Institute, 1985.

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Espinosa, Restrepo Helena, Adult Health Program (Pan American Health Organization) e Programa de Tecnología en Salud (Pan American Health Organization), a cura di. Effectiveness of cervical cancer screening programs: Annotated bibliography. Washington, D.C: Pan American Health Organization, Pan American Sanitary Bureau, Regional Office of the World Health Organization, 1986.

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Vaillancourt, Pauline M. Cancer journals and serials: An analytical guide. New York: Greenwood Press, 1988.

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Technassociates, a cura di. Annotated bibliography of the literature on cancer in Hispanics for the Hispanic Cancer Control Program. Bethesda, Md.]: The Institute, 1986.

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Più fonti

Capitoli di libri sul tema "Cancer, bibliography"

1

Amaral Mendes, Jose Jeronimo, e Eric Pluygers. "Risk Assessment and Chemical and Radiation Hormesis: A Short Commentary and Bibliographic Review". In Recent Advances in Quantitative Methods in Cancer and Human Health Risk Assessment, 97–109. Chichester, UK: John Wiley & Sons, Ltd, 2006. http://dx.doi.org/10.1002/0470857706.ch6.

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"BIBLIOGRAPHY". In Cancer, 297–302. University of California Press, 2023. http://dx.doi.org/10.2307/jj.8137446.25.

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"BIBLIOGRAPHY". In Enduring Cancer, 205–18. Duke University Press, 2020. http://dx.doi.org/10.1515/9781478012214-010.

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"Bibliography". In Enduring Cancer, 205–18. Duke University Press, 2020. http://dx.doi.org/10.1215/9781478012214-009.

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"BIBLIOGRAPHY". In Enduring Cancer, 205–18. Duke University Press, 2020. http://dx.doi.org/10.2307/j.ctv14t48jz.12.

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"Bibliography". In Personalised cancer medicine. Manchester University Press, 2021. http://dx.doi.org/10.7765/9781526141019.00013.

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"Bibliography". In Advances in Cancer Research, 204–56. Elsevier, 1986. http://dx.doi.org/10.1016/s0065-230x(08)60047-0.

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"Bibliography". In Encyclopedia of Hereditary Cancer, 365–88. Elsevier, 2024. http://dx.doi.org/10.1016/b978-0-443-13575-0.00225-1.

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"Bibliography". In Living and Dying with Cancer, 182–86. Cambridge University Press, 2004. http://dx.doi.org/10.1017/cbo9780511489396.009.

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"Bibliography". In Environmental Cancer—A Political Disease?, 201–24. Yale University Press, 1999. http://dx.doi.org/10.2307/j.ctt32bp19.11.

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Atti di convegni sul tema "Cancer, bibliography"

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Romanu, Ramona Maria, Anton Alina, Maria Roberta Tripon, Cristina Dehelean e Camelia Tulcan. "CYTOTOXIC EFFECT OF CHELIDONIUM MAJUS FREEZE DRYED EXTRACT: IN VITRO STUDY ON SKIN CANCER LINE". In 23rd SGEM International Multidisciplinary Scientific GeoConference 2023. STEF92 Technology, 2023. http://dx.doi.org/10.5593/sgem2023v/6.2/s25.15.

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The multiple therapeutic properties of Chelidonium majus are known and well documented in the bibliography, being used for a long time in Chinese homeopathic medicine [1]. At the level of the skin, in traditional folk medicine, C. majus is used to treat warts, condylomas, and papillae, which are due to human papillomavirus (HPV) infections [2, 3]. In this context, the aim of this study was to assess the potential antitumor effects of C. majus extracts on human melanoma cells - A375 - and to evaluate it in terms of cell viability and morphology changes. Thus, an extract of C. majus (C_ex) was obtained in order to assess its potential antitumor effects. This extract was then tested on human melanoma cells - A375 - and evaluated in terms of cell viability and morphology changes. The results of the study highlighted the potential cytotoxic effect of C_ex on melanoma cells. It was observed that cell viability decreased in a dose-dependent manner after 24 hours. Moreover, the morphological changes are consistent with those observed following a cell viability test, exhibiting the characteristic signs of cell death.

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Lucas-Domínguez, Rut, Rubén Fernández Gascón, Yiming Liu, ANDREA SIXTO COSTOYA, Cristina Rius e Juan Carlos Valderrama-Zurián. "Availability of raw data in Spanish cancer research". In 27th International Conference on Science, Technology and Innovation Indicators (STI 2023). International Conference on Science, Technology and Innovation Indicators, 2023. http://dx.doi.org/10.55835/6440e5e8f35cd8cad1785cc0.

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This study aims to analyze the availability of research data deposited by Spanish authors in the area of cancer. A bibliographic search of raw data signed by at least one Spanish author and published in the period 2011-2021 was carried out using the Data Citation Index. This study revealed a total of 2,693 registers from 2,679 authors, being Gene Expression Omnibus, the main repository used.

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Chagas, Carlos Ricardo, Haroldo Nonato Ferreira de Souza, Gabriela Del Prete Magalhães, Sálua Saud Bedran e Natascha Carneiro Chagas. "DIAGNOSIS OF BREAST CANCER ASSOCIATED WITH PREGNANCY: A REVIEW OF LITERATURE". In XXIV Congresso Brasileiro de Mastologia. Mastology, 2022. http://dx.doi.org/10.29289/259453942022v32s1025.

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Introduction: The diagnosis of breast cancer in pregnant and postpartum women presents challenges. The clinical management of the breasts during pregnancy and lactation requires knowledge of the physiological changes of the pregnant breast, as well as the correct identification and approach to possible changes. The reluctance of physicians and patients to perform radiographic tests and invasive procedures during this period should be discussed. Objective: The aim of this study was to demonstrate that all breast lesions found in these periods should be carefully evaluated, highlighting the importance of diagnostic evaluation methods, comparing the advantages, disadvantages, and possible false-negative factors of the methods frequently used in clinical practice. Methods: This is a literature review, which uses references found in scientific books on gynecology, obstetrics, and mastology, in addition to the use of the databases Medline, BVS, PubMed, UpToDate, and LILACS, applying to originals and literature reviews written in English, Portuguese, and Spanish. Results: The analysis of diagnostic methods in the context of breast cancer is associated with pregnancy, such as selfexamination, anamnesis and clinical examination, ultrasonography, mammography, evaluation by core biopsy, evaluation by cytology, and evaluation by magnetic resonance imaging, presented as a result of limitations not found in nonpregnant women. The bibliographic study points to the need for individualized monitoring, analysis, and application, taking into consideration a woman’s risk of developing breast cancer during her pregnancy and physiological and morphological changes in the breast. Conclusion: Early diagnosis is not common during pregnancy; consequently, more advanced stages are associated with breast cancer simultaneously to gestation. Therefore, even in pregnancy, any suspicion of breast lesion must undergo evaluation. Pregnant and postpartum women should have clinical breast examinations as a routine, making patients and health staff aware of their importance in the pregnancy-puerperal cycle. Advice about the self-examination, request for ultrasound, mammography, and biopsy is necessary.

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Vieira Ferreira, Gustavo, Weliton Dal Pizzol Maria e Adriano Rodrigues de Melo. "Introdução à Geometria Fractal no Ensino Médio Técnico: Uma Abordagem com Programação Python". In Computer on the Beach. São José: Universidade do Vale do Itajaí, 2021. http://dx.doi.org/10.14210/cotb.v12.p543-546.

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This work is inserted in the context of technical high school andit aimed to analyze the integration between the branches of FractalGeometry, Analytical Geometry and Computer Programming.For this purpose, we carried out a bibliographic search about whatcharacterizes and distinguishes Fractal Geometry from EuclideanGeometry, we also seek in our readings to list the most famousfractals. Then, we developed (in python language) several fractalgeneration programs. It was possible to work with amazing andeasily programmable fractal shapes, such as the Cantor Set, theHilbert Curve and Sierpinski Triangle. We also built two new familiesof fractal shapes from a generalization of the Koch Curve. Weconclude that programming fractals in the context of technical highschool is productive and challenging, as it requires many changesin the representations of fractal patterns.

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Vieira, Natália Barros Salgado, Sarah Joanny da Silva Pereira e Ana Flávia Silva Castro. "Neurocognitive Implications in Children Undergoing Chemotherapy and Radiotherapy". In XIII Congresso Paulista de Neurologia. Zeppelini Editorial e Comunicação, 2021. http://dx.doi.org/10.5327/1516-3180.499.

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Background: Radiotherapy and chemotherapy drugs were essential for increasing the survival rates of pediatric cancer patients, but dysfunctions associated with treatment, mainly neurological and cognitive, are recorded and should be considered in deciding the therapeutic plan. Objectives: Analyze the current literature on the neurocognitive effects in children undergoing chemotherapy and radiation therapy. Methods: A bibliographic review was carried out in the MEDLINE / Pubmed and LILACS databases, using the terms “cognitive effects”, “chemotherapy”, “radiotherapy” and “child”, in Portuguese and in English. 79 articles were found and 6 followed for complete analysis. Articles published more than 5 years ago and that did not address the proposed subject were not used. Results: Radiotherapy, especially cranial (CRT), is associated with serious effects, such as induction of vasculopathy, stroke, cerebrovascular malformations, in addition to an increased risk for subsequent malignant CNS tumors. Despite being a standard treatment for several neoplasms, radiotherapy has been replaced, when possible, by higher doses of chemotherapy, which has a considerable level of neurotoxicity, capable of causing coagulopathy, encephalopathy, seizures and neuropathies, both sensory and motor. However, deficits in children’s attentional capacity in both treatment categories stood out, sometimes implying educational difficulties and decline in non-verbal skills. Conclusions: Although chemotherapy and radiation therapy represent impressive advances, their consequences remain a concern. Future studies should seek strategies for prevention, early recognition and management of neurotoxicity, in order to promote better life quality for patients.

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Duarte, Madileide de Oliveira. "The third bank of the river and interfaces between short stories, theater and soap operas". In VI Seven International Multidisciplinary Congress. Seven Congress, 2024. http://dx.doi.org/10.56238/sevenvimulti2024-017.

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The aim of this research was to present possible interfaces between the short story A Terceira Margem do Rio by João Guimarães Rosa; the play Terceira Margem , directed and performed by Carlos Lagoeiro; and the soap opera Pantanal , a 1990 version, written by Benedito Ruy Barbosa, directed by Jayme Monjardim, Carlos Magalhães, Marcelo de Barreto and Roberto Naar. The methodology was based on the comparison of existing literature, both bibliographic and digital, combined with my qualitative interpretation, through interfaces, in the intersemiotic field. Main results: 1) narrative adaptation, between the short story and the theater, was achieved through the director/actor's monologue, wooden puppets and their speeches, canoes and the symbolism of the river; 2) approximations between the short story and the soap opera: a) narratives involving the supernatural - Juma (a jaguar-woman), the mysterious guitarist Trindade and the old man of the river and his transformation into the snake Sucuri; b) setting between scenarios; c) the characters' speeches; d) the waters of the São Francisco River and the Rio Negro and their re-significations for each narrative (the short story, the theater and the soap opera).

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Torres, Klícia da Silva. "Sustainable development in sugarcane plants: the crucial role of labor law". In V Seven International Multidisciplinary Congress. Seven Congress, 2024. http://dx.doi.org/10.56238/sevenvmulti2024-111.

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Labor law plays a crucial role in regulating labor relations in sugarcane mills, a sector of great economic importance in Brazil. In the current context, there is a growing concern about promoting sustainable development in this segment, considering the socio-environmental impacts of sugarcane production. This study aims to analyze the interaction between labor law, sugarcane mills and sustainable development. It only represents a starting point for further investigation. The aim is to investigate how labor laws can contribute to improving working conditions in plants, while promoting sustainable production practices. The research was conducted through bibliographic review and document analysis. Scientific articles, labor legislation and studies on sustainable development in the context of sugar cane mills were reviewed. In addition, reports from companies in the sector and government data related to working conditions and environmental impacts were analyzed. The results revealed that labor legislation plays a fundamental role in protecting the rights of workers in sugarcane mills, addressing issues such as working hours, safety and occupational health. However, there are still challenges to be faced, such as informality and precarious work in some regions. The discussion points to the need for public policies and business practices aimed at promoting sustainable development in the sugar and alcohol sector. This includes investments in clean technologies, responsible environmental management and corporate social responsibility programs. It is concluded that labor law plays an important role in promoting sustainable development in sugarcane mills, by guaranteeing decent working conditions and promoting social justice. However, a joint effort by governments, companies and civil society is needed to face socio-environmental challenges and guarantee a sustainable future for the sector.

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Rapporti di organizzazioni sul tema "Cancer, bibliography"

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Dioguardi, Mario, e Diego Sovereto. Application of the Extracts of Pomegranate in Oral Cancer. INPLASY - International Platform of Registered Systematic Review and Meta-analysis Protocols, settembre 2022. http://dx.doi.org/10.37766/inplasy2022.9.0027.

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Review question / Objective: In this scoping review we will focus on identifying those studies that investigated the effects of Punica granatum extracts on oral cancer and more specifically on OSCCs, summarizing the main results and the state of the research at the present time. Eligibility criteria: All studies investigating Punica granatum L. in association with oral and precancerous cancer were considered potentially admissible, no restrictions were applied in relation to the year of publication and based on the language provided that an abstract in English is available. literature reviews were excluded and were used only as sources for bibliographic research.

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Dahm, Philipp, Michelle Brasure, Elizabeth Ester, Eric J. Linskens, Roderick MacDonald, Victoria A. Nelson, Charles Ryan et al. Therapies for Clinically Localized Prostate Cancer. Agency for Healthcare Research and Quality (AHRQ), settembre 2020. http://dx.doi.org/10.23970/ahrqepccer230.

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Objective. To update findings from previous Agency for Healthcare Research and Quality (AHRQ)- and American Urological Association (AUA) funded reviews evaluating therapies for clinically localized prostate cancer (CLPC). Sources. Bibliographic databases (2013–January 2020); ClinicalTrials.gov; systematic reviews Methods. Controlled studies of CLPC treatments with duration ≥5 years for mortality and metastases and ≥1 year for quality of life and harms. One investigator rated risk of bias (RoB), extracted data, and assessed certainty of evidence; a second checked accuracy. We analyzed English-language studies with low or medium RoB. We incorporated findings from randomized controlled trials (RCTs) identified in the prior reviews if new RCTs provided information on the same intervention comparison. Results. We identified 67 eligible references; 17 were unique RCTs. Among clinically rather than prostate specific antigen (PSA) detected CLPC, Watchful Waiting (WW) may increase mortality and metastases versus Radical Prostatectomy (RP) at 20+ years. Urinary and erectile dysfunction were lower with WW versus RP. WW’s effect on mortality may vary by tumor risk and age but not by race, health status, comorbidities, or PSA. Active Monitoring (AM) probably results in little to no difference in mortality in PSA detected CLPC versus RP or external beam radiation (EBR) plus Androgen Deprivation (AD) regardless of tumor risk. Metastases were slightly higher with AM. Harms were greater with RP than AM and mixed between EBR plus AD versus AM. 3D-conformal EBR and AD plus low-dose-rate brachytherapy (BT) provided a small reduction in all-cause mortality versus three dimensional conformal EBR and AD but little to no difference on metastases. EBR plus AD versus EBR alone may result in a small reduction in mortality and metastases in higher risk disease but may increase sexual harms. EBR plus neoadjuvant AD versus EBR plus concurrent AD may result in little to no difference in mortality and genitourinary toxicity. Conventionally fractionated EBR versus ultrahypofractionated EBR may result in little to no difference in mortality and metastases and urinary and bowel toxicity. Active Surveillance may result in fewer harms than photodynamic therapy and laparoscopic RP may result in more harms than robotic-assisted RP. Little information exists on other treatments. No studies assessed provider or hospital factors of RP comparative effectiveness. Conclusions. RP reduces mortality versus WW in clinically detected CLPC but causes more harms. Effectiveness may be limited to younger men or to those with intermediate risk disease and requires many years to occur. AM results in little to no mortality difference versus RP or EBR plus AD. EBR plus AD reduces mortality versus EBR alone in higher risk CLPC but may worsen sexual function. Adding low-dose-rate BT to 3D-conformal EBR and AD may reduce mortality in higher risk CLPC. RCTs in PSA-detected and MRI staged CLPC are needed.

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Hajarizadeh, Behzad, Jennifer MacLachlan, Benjamin Cowie e Gregory J. Dore. Population-level interventions to improve the health outcomes of people living with hepatitis B: an Evidence Check brokered by the Sax Institute for the NSW Ministry of Health, 2022. The Sax Institute, agosto 2022. http://dx.doi.org/10.57022/pxwj3682.

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Background An estimated 292 million people are living with chronic hepatitis B virus (HBV) infection globally, including 223,000 people in Australia. HBV diagnosis and linkage of people living with HBV to clinical care is suboptimal in Australia, with 27% of people living with HBV undiagnosed and 77% not receiving regular HBV clinical care. This systematic review aimed to characterize population-level interventions implemented to enhance all components of HBV care cascade and analyse the effectiveness of interventions. Review questions Question 1: What population-level interventions, programs or policy approaches have been shown to be effective in reducing the incidence of hepatitis B; and that may not yet be fully rolled out or evaluated in Australia demonstrate early effectiveness, or promise, in reducing the incidence of hepatitis B? Question 2: What population-level interventions and/or programs are effective at reducing disease burden for people in the community with hepatitis B? Methods Four bibliographic databases and 21 grey literature sources were searched. Studies were eligible for inclusion if the study population included people with or at risk of chronic HBV, and the study conducted a population-level interventions to decrease HBV incidence or disease burden or to enhance any components of HBV care cascade (i.e., diagnosis, linkage to care, treatment initiation, adherence to clinical care), or HBV vaccination coverage. Studies published in the past 10 years (since January 2012), with or without comparison groups were eligible for inclusion. Studies conducting an HBV screening intervention were eligible if they reported proportion of people participating in screening, proportion of newly diagnosed HBV (participant was unaware of their HBV status), proportion of people received HBV vaccination following screening, or proportion of participants diagnosed with chronic HBV infection who were linked to HBV clinical care. Studies were excluded if study population was less than 20 participants, intervention included a pharmaceutical intervention or a hospital-based intervention, or study was implemented in limited clinical services. The records were initially screened by title and abstract. The full texts of potentially eligible records were reviewed, and eligible studies were selected for inclusion. For each study included in analysis, the study outcome and corresponding 95% confidence intervals (95%CIs) were calculated. For studies including a comparison group, odds ratio (OR) and corresponding 95%CIs were calculated. Random effect meta-analysis models were used to calculate the pooled study outcome estimates. Stratified analyses were conducted by study setting, study population, and intervention-specific characteristics. Key findings A total of 61 studies were included in the analysis. A large majority of studies (study n=48, 79%) included single-arm studies with no concurrent control, with seven (12%) randomised controlled trials, and six (10%) non-randomised controlled studies. A total of 109 interventions were evaluated in 61 included studies. On-site or outreach HBV screening and linkage to HBV clinical care coordination were the most frequent interventions, conducted in 27 and 26 studies, respectively. Question 1 We found no studies reporting HBV incidence as the study outcome. One study conducted in remote area demonstrated that an intervention including education of pregnant women and training village health volunteers enhanced coverage of HBV birth dose vaccination (93% post-intervention, vs. 81% pre-intervention), but no data of HBV incidence among infants were reported. Question 2 Study outcomes most relevant to the HBV burden for people in the community with HBV included, HBV diagnosis, linkage to HBV care, and HBV vaccination coverage. Among randomised controlled trials aimed at enhancing HBV screening, a meta-analysis was conducted including three studies which implemented an intervention including community face-to-face education focused on HBV and/or liver cancer among migrants from high HBV prevalence areas. This analysis demonstrated a significantly higher HBV testing uptake in intervention groups with the likelihood of HBV testing 3.6 times higher among those participating in education programs compared to the control groups (OR: 3.62, 95% CI 2.72, 4.88). In another analysis, including 25 studies evaluating an intervention to enhance HBV screening, a pooled estimate of 66% of participants received HBV testing following the study intervention (95%CI: 58-75%), with high heterogeneity across studies (range: 17-98%; I-square: 99.9%). A stratified analysis by HBV screening strategy demonstrated that in the studies providing participants with on-site HBV testing, the proportion receiving HBV testing (80%, 95%CI: 72-87%) was significantly higher compared to the studies referring participants to an external site for HBV testing (54%, 95%CI: 37-71%). In the studies implementing an intervention to enhance linkage of people diagnosed with HBV infection to clinical care, the interventions included different components and varied across studies. The most common component was post-test counselling followed by assistance with scheduling clinical appointments, conducted in 52% and 38% of the studies, respectively. In meta-analysis, a pooled estimate of 73% of people with HBV infection were linked to HBV clinical care (95%CI: 64-81%), with high heterogeneity across studies (range: 28-100%; I-square: 99.2%). A stratified analysis by study population demonstrated that in the studies among general population in high prevalence countries, 94% of people (95%CI: 88-100%) who received the study intervention were linked to care, significantly higher than 72% (95%CI: 61-83%) in studies among migrants from high prevalence area living in a country with low prevalence. In 19 studies, HBV vaccination uptake was assessed after an intervention, among which one study assessed birth dose vaccination among infants, one study assessed vaccination in elementary school children and 17 studies assessed vaccination in adults. Among studies assessing adult vaccination, a pooled estimate of 38% (95%CI: 21-56%) of people initiated vaccination, with high heterogeneity across studies (range: 0.5-93%; I square: 99.9%). A stratified analysis by HBV vaccination strategy demonstrated that in the studies providing on-site vaccination, the uptake was 78% (95%CI: 62-94%), significantly higher compared to 27% (95%CI: 13-42%) in studies referring participants to an external site for vaccination. Conclusion This systematic review identified a wide variety of interventions, mostly multi-component interventions, to enhance HBV screening, linkage to HBV clinical care, and HBV vaccination coverage. High heterogeneity was observed in effectiveness of interventions in all three domains of screening, linkage to care, and vaccination. Strategies identified to boost the effectiveness of interventions included providing on-site HBV testing and vaccination (versus referral for testing and vaccination) and including community education focussed on HBV or liver cancer in an HBV screening program. Further studies are needed to evaluate the effectiveness of more novel interventions (e.g., point of care testing) and interventions specifically including Indigenous populations, people who inject drugs, men who have sex with men, and people incarcerated.

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Bibliography of CANMET publications on coprocessing. Natural Resources Canada/ESS/Scientific and Technical Publishing Services, 1988. http://dx.doi.org/10.4095/302695.

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Bibliography of CANMET publications on coprocessing. Natural Resources Canada/ESS/Scientific and Technical Publishing Services, 1989. http://dx.doi.org/10.4095/304446.

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