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Letteratura scientifica selezionata sul tema "Bone-grafting"

Autore: Grafiati

Pubblicato: 4 giugno 2021

Ultima modifica: 9 giugno 2025

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Articoli di riviste sul tema "Bone-grafting"

SM, Harsini. "Bone Regenerative Medicine and Bone Grafting." Open Access Journal of Veterinary Science & Research 3, no. 4 (2018): 1–7. http://dx.doi.org/10.23880/oajvsr-16000167.

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Bone tissues can repair and regenerate it: in many clinical cases, bone fractures repair without scar formation. Nevertheless, in large bone defects and pathological fractures, bone healing fail to heal. Bone grafting is defined as implantation of material which promot es fracture healing, through osteoconduction osteogenesis, and osteoinduction. Ideal bone grafting depends on several factors such as defect size, ethical issues, biomechanical characteristics, tissue viability, shape and volume, associated complications, cost, graft size, graft handling, and biological characteristics. The materials that are used as bone graft can be divided into separate major categories, such as autografts, allografts, and xenografts. Synthetic substitutes and tissue - engineered biomateri als are other options. Each of these instances has some advantages and disadvantages. Between the all strategies for improving fracture healing and enhance the outcome of unification of the grafts, tissue engineering is a suitable option. A desirable tissu e - engineered bone must have properties similar to those of autografts without their limitations. None of the used bone grafts has all the ideal properties including low donor morbidity, long shelf life, efficient cost, biological safety, no size restrictio n, and osteoconductive, osteoinductive, osteogenic, and angiogenic properties; but Tissue engineering tries to supply most of these features. In addition it is able to induce healing and reconstruction of bone defects. Combining the basis of orthopedic sur gery with knowledge from different sciences like materials science, biology, chemistry, physics, and engineering can overcome the limitations of current therapies. Combining the basis of orthopedic surgery with knowledge from different sciences like materi als science, biology, chemistry, physics, and engineering can overcome the limitations of current therapies.

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Zipfel, Gregory J., Bernard H. Guiot, and Richard G. Fessler. "Bone grafting." Neurosurgical Focus 14, no. 2 (February 2003): 1–8. http://dx.doi.org/10.3171/foc.2003.14.2.9.

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In recent years our understanding of spinal fusion biology has improved. This includes the continued elucidation of the step-by-step cellular and molecular events involved in the prototypic bone induction cascade, as well as the identification and characterization of the various critical growth factors governing the process of bone formation and bone graft incorporation. Based on these fundamental principles, growth factor technology has been exploited in an attempt to improve rates of spinal fusion, and promising results have been realized in preclinical animal studies and initial clinical human studies. In this article the authors review the recent advances in the biology of bone fusion and provide a perspective on the future of spinal fusion, a future that will very likely include increased graft fusion rates and improved patient outcome as a result of the successful translation of fundamental bone fusion principles to the bedside.

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Buddecke, Donald E., Lesley N. Lile, and Eric A. Barp. "Bone Grafting." Clinics in Podiatric Medicine and Surgery 18, no. 1 (January 2001): 109–45. http://dx.doi.org/10.1016/s0891-8422(23)01170-9.

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YT, Konttinen, Waris E, Xu J-W, Lassus J, Salo J, Nevalainen J, and Santatvirta S. "Bone grafting." Journal of Orthopaedic Nursing 3, no. 1 (February 1999): 52. http://dx.doi.org/10.1016/s1361-3111(99)80090-9.

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Pikos, Michael A. "Bone grafting." Journal of Oral and Maxillofacial Surgery 61, no. 8 (August 2003): 7. http://dx.doi.org/10.1016/s0278-2391(03)00346-x.

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Alexander, J. W. "Bone Grafting." Veterinary Clinics of North America: Small Animal Practice 17, no. 4 (July 1987): 811–19. http://dx.doi.org/10.1016/s0195-5616(87)50078-x.

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Konttinen, YrjöT, Eero Waris, Jing-Wen Xu, Jan Lassus, Jari Salo, Seppo Santavirta, and Juha Nevalainen. "Bone grafting." Current Orthopaedics 12, no. 3 (July 1998): 209–15. http://dx.doi.org/10.1016/s0268-0890(98)90026-3.

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&NA;. "BONE GRAFTING." Plastic and Reconstructive Surgery 82, no. 4 (October 1988): 739. http://dx.doi.org/10.1097/00006534-198810000-00105.

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Egol, Kenneth A., Aaron Nauth, Mark Lee, Hans-Christoph Pape, J. Tracy Watson, and Joseph Borrelli. "Bone Grafting." Journal of Orthopaedic Trauma 29 (December 2015): S10—S14. http://dx.doi.org/10.1097/bot.0000000000000460.

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Eppley, Barry L. "Alveolar cleft bone grafting (Part I): Primary bone grafting." Journal of Oral and Maxillofacial Surgery 54, no. 1 (January 1996): 74–82. http://dx.doi.org/10.1016/s0278-2391(96)90310-9.

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Tesi sul tema "Bone-grafting"

Herbert, Amy Angharad. "Bone grafting : tissue treatment and osseointegration." Thesis, Cardiff University, 2004. http://orca.cf.ac.uk/55547/.

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Bone grafts fill skeletal defects and provide a structure upon which new bone can be deposited. There is no standard method of storing bone prior to grafting, the three main storage regimes being stored fresh frozen at -80°C, gamma irradiated or freeze dried. The initial aim of this project was to determine how osteoblastic cells behaved when exposed to bone treated in the above ways. It was found that sterilisation of bone with gamma irradiation caused cell death in a number of the cells that came into contact with it. Therefore the use of gamma irradiation for grafting is contraindicated, a similar observation was observed for freeze-dried bone whereas cells grew and differentiated on fresh frozen tissue. The second aim of this study was to develop a system whereby bone marrow cells could be expanded in culture and retain their osteogenic potential so that they would be suitable for either coating a bone graft (thus increasing the rate of osseointegration of the graft) or used alone to treat small bone defects. Rodent bone marrow was used in a variety of cultures and bone formation was induced by either BGJ-b medium or ECCM (Endothelial cell conditioned medium). Control cultures were grown in alpha modification minimum essential medium. ECCM was overall found to produce a greater number of cells at the end of the incubation periods studied than BGJ-b medium. BGJ-b medium preferentially selected mineralization over cell proliferation under all of the culture conditions studied (monolayers, collagen gels and organ cultures). This medium would be best suited to forming small pieces of bone rapidly from bone marrow, to fill small bone defects such as those seen in the dental field. ECCM produced large numbers of osteogenic cells, which could potentially be used to coat large bone grafts.

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Mak, Siu Yan. "Mechanical factors influencing impaction bone grafting." Thesis, University of Bath, 2007. https://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.486839.

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Impaction grafting for bone stock loss in revision total hip arthroI;>lasty has been used for over a decade. This technique typically involves the insertion of a cemented highly polished stem into impacted morsellised allograft bone. The aim is to compensate for the bone stock loss after failed primary hip arthroplasty and to provide a mechanical and biological scaffold for mechanical support and bone remodelling. The primary objective of this study is to quantify and optimise the graft properties so as to provide maximum supportive forces to the stem, and, at' the same time, to minimise the amount of per.:operative and post-operative femoral fractures. More than 60 parameters that could affect the mechanical properties of graft have been identified. Porcine bone from femoral heads was used in the study which was primarily divided into two parts: fundamental studies of the graft material, and in-vitro mechanical testing to replicate the clinical application of impaction bone grafting. Various techniques of graft preparation including defatting of the graft were investigated. A die-plunger was employed to perform uni-axial compressive testing on the graft at varying strain rates. It was found that defatted' graft demonstrated higher stiffness. Higher rates of loading resulted in increases in stiffness, hoop strain, axial force and Poisson's ratio. Preloading of the graft provided more predictable mechanical characteristics. Cyclic compressive testing showed th~t individual graft particles fractured during compression. In addition, it was found that the graft demonstrated increased viscoelastic properties at higher strain rates. In-vitro mechanical testing was also performed to compare the level of mechanical stability of a cemented polished stem with a larger uncemented polished stem. Composite femora were '' used for this comparison. It was found that the cemented stem showed higher mechanical stability in terms of the level of micromotion and migration, and uncemented stem failed in a catastrophic manner. The study provided information on how various factors contributed to the mechanical behaviour of bone graft and identified parameters that should be used when in-vitro testing of bone graft materials for use in impaction grafting.

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Twitty, Anne. "The expression of tissue inhibitor of metalloproteinase during the early stages of bone graft healing." Thesis, Hong Kong : University of Hong Kong, 2000. http://sunzi.lib.hku.hk/hkuto/record.jsp?B21804023.

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Dattani, Rupen. "Femoral impaction grafting : using bone graft substitutes." Thesis, University College London (University of London), 2008. http://discovery.ucl.ac.uk/1444261/.

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Background: Femoral impaction allografting to reconstitute bone loss during revision hip surgery has shown excellent results. However, limitations with the use of allografts have warranted research to investigate if bone graft substitutes could be a suitable alternative to replace or augment allograft in impaction grafting.;Aims and Methods: The objectives of this thesis were to assess if: The use of hydroxyapatite (HA) in various combinations with allograft will be biologically effective and functionally stable using a cemented impaction grafting technique in an ovine hemiarthroplasty model. The different treatment groups were compared by measuring the ground reaction forces and new bone formation. The addition of mesenchymal stem cells (MSCs) to allograft, HA or an allograft:HA mixture enhances the amount of new bone formation compared with impaction of the scaffold alone in an ovine metaphyseal femoral bone defect model. The architecture of the HA scaffold influences bone formation in an extra-skeletal sheep model.;Results: HA: allograft mixture of up to 90:10 demonstrated similar functional stability and amount of new bone formation as a 50:50 mixture. Addition of MSCs to allograft or a 50:50 allograft:HA mixture enhances the amount of new bone formation compared with unimpacted constructs. HA either alone or combined with MSCs induces bone growth only when constructed in block form and not in identical porous granular form.;Conclusion: HA is a suitable bone substitute to augment allograft and may be replace bone graft completely in impaction grafting of a femoral component. This has important clinical implications as HA is readily available, easy to use in surgery and not associated with the adverse effects encountered with allografts. The use of MSCs in the treatment of osteolysis holds great potential but further work is required to assess if this technology is transferable to humans.

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黃美娟 and May-kuen Alice Wong. "Bone induction of demineralized intramembranous and endochondral bone matrices." Thesis, The University of Hong Kong (Pokfulam, Hong Kong), 1999. http://hub.hku.hk/bib/B3197305X.

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Wong, May-kuen Alice. "Bone induction of demineralized intramembranous and endochondral bone matrices." View the Table of Contents & Abstract, 1999. http://sunzi.lib.hku.hk/hkuto/record.jsp?B21872752.

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Thorén, Klas. "Lipid-extracted bone grafts." Lund : Dept. of Orthopedics, University Hospital, Lund University, 1994. http://catalog.hathitrust.org/api/volumes/oclc/39676934.html.

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Lie, Ken Jie Ronny Ket Phoei. "The healing of composite endochondral bone grafts a qualitative and quantitative analysis /." Hong Kong : Faculty of Dentistry, The University of Hong Kong, 1995. http://sunzi.lib.hku.hk/HKUTO/record/B38628120.

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李國培 and Ken Jie Ronny Ket Phoei Lie. "The healing of composite endochondral bone grafts: a qualitative and quantitative analysis." Thesis, The University of Hong Kong (Pokfulam, Hong Kong), 1995. http://hub.hku.hk/bib/B38628120.

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McNamara, Iain Robert. "Characterisation of the mechanical response of morcellised bone graft and bone graft substitutes for impaction grafting." Thesis, University of Cambridge, 2010. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.608923.

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Libri sul tema "Bone-grafting"

E, Friedlander Gary, ed. Bone grafting. Philadelphia, PA: W.B. Saunders, 1987.

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Older, M. W. J., ed. Bone Implant Grafting. London: Springer London, 1992. http://dx.doi.org/10.1007/978-1-4471-1934-0.

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1935-, Older John, ed. Bone implant grafting. London: Springer-Verlag, 1992.

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Older, M. W. J. Bone Implant Grafting. London: Springer London, 1992.

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Leung, Ping-Chung. Current Trends in Bone Grafting. Berlin, Heidelberg: Springer Berlin Heidelberg, 1989. http://dx.doi.org/10.1007/978-3-642-73970-5.

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1948-, Davies J. E., and Bone-Biomaterial Interface Workshop (1990 : Toronto, Ont.), eds. The Bone-biomaterial interface. Toronto: University of Toronto Press, 1991.

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Kahnberg, Karl-Erik, ed. Bone Grafting Techniques for Maxillary Implants. Oxford, UK: Blackwell Munksgaard, 2005. http://dx.doi.org/10.1002/9780470759578.

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Y, Shin Alexander, and Moran Steven L, eds. Vascularized bone grafting in orthopedic surgery. Philadelphia: Saunders, 2006.

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Kahnberg, Karl-Erik. Bone grafting techniques for maxillary implants. Oxford: Blackwell Munksgaard, 2005.

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1962-, Rasmusson Lars, and Zellin Göran 1962-, eds. Bone grafting techniques for maxillary implants. Oxford: Blackwell Munksgaard, 2005.

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Capitoli di libri sul tema "Bone-grafting"

Sheikh, Zeeshan, Siavash Hasanpour, and Michael Glogauer. "Bone Grafting." In Mandibular Implant Prostheses, 155–74. Cham: Springer International Publishing, 2018. http://dx.doi.org/10.1007/978-3-319-71181-2_9.

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Vinci, Raffaele. "Bone Grafting." In Implants and Oral Rehabilitation of the Atrophic Maxilla, 209–30. Cham: Springer International Publishing, 2023. http://dx.doi.org/10.1007/978-3-031-12755-7_9.

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Czitrom, A. A. "Bone Banking." In Bone Implant Grafting, 209–11. London: Springer London, 1992. http://dx.doi.org/10.1007/978-1-4471-1934-0_26.

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Czitrom, A. A. "Immunology of Bone Grafting." In Bone Implant Grafting, 3–7. London: Springer London, 1992. http://dx.doi.org/10.1007/978-1-4471-1934-0_1.

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Chandler, H. P. "Revision of the Acetabular Component." In Bone Implant Grafting, 63–69. London: Springer London, 1992. http://dx.doi.org/10.1007/978-1-4471-1934-0_10.

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Gross, A. E. "Banked Allograft Bone for Proximal Femoral Deficiency." In Bone Implant Grafting, 73–75. London: Springer London, 1992. http://dx.doi.org/10.1007/978-1-4471-1934-0_11.

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Loty, B., and M. Postel. "Allograft Bone in Major Revision Hip Replacement Surgery." In Bone Implant Grafting, 77–90. London: Springer London, 1992. http://dx.doi.org/10.1007/978-1-4471-1934-0_12.

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Paprosky, W. G. "The Use of Femoral Strut Grafts in Cementless Revision Arthroplasty." In Bone Implant Grafting, 91–100. London: Springer London, 1992. http://dx.doi.org/10.1007/978-1-4471-1934-0_13.

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Hedley, A. K. "Allografts in Major Revision Total Hip Surgery." In Bone Implant Grafting, 101–10. London: Springer London, 1992. http://dx.doi.org/10.1007/978-1-4471-1934-0_14.

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Goldberg, V. M. "Bone Grafting in Revision Total Hip Surgery." In Bone Implant Grafting, 111–15. London: Springer London, 1992. http://dx.doi.org/10.1007/978-1-4471-1934-0_15.

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Atti di convegni sul tema "Bone-grafting"

Samarawickrama, Kasun G. "A Review on Bone Grafting, Bone Substitutes and Bone Tissue Engineering." In the 2nd International Conference. New York, New York, USA: ACM Press, 2018. http://dx.doi.org/10.1145/3239438.3239457.

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JIAN, Mariana, Denisa FICAI, and Viorel NACU. "Challenges and solutions in bone tissue engineering." In International congress "Research-Innovation-Inovative Entreneurship", 17–24. Ion Creangă Pedagogical State University, 2024. http://dx.doi.org/10.46727/c.13-14-10-2023.p17-24.

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The present work is focused on presenting the challenges and the recent advances in the field of Bone Tissue Engineering. It has to mention that worldwide, the need of bone grafting materials is only exceeded by the need of blood. Some of the most relevant materials used in bone grafting will be presented considering the compositional and morphological similitude with the bone but also the specific needs associated with different pathologies.

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Кобызев, А. Е., В. В. Краснов, and Ю. Ю. Литвинов. "THE USE OF BONE GRAFTING IN PRACTICAL MEDICINE." In ОТ БИОХИМИИ РАСТЕНИЙ К БИОХИМИИ ЧЕЛОВЕКА. Москва: Федеральное государственное бюджетное научное учреждение "Всероссийский научно-исследовательский институт лекарственных и ароматических растений", 2022. http://dx.doi.org/10.52101/9785870191041_369.

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Vivanco, Juan, Josh Slane, and Heidi Ploeg. "Nano-Mechanical Properties of Bioceramic Bone Scaffolds Fabricated at Three Sintering Temperatures." In ASME 2011 Summer Bioengineering Conference. American Society of Mechanical Engineers, 2011. http://dx.doi.org/10.1115/sbc2011-53734.

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Bone grafting is an exceptionally common procedure used to repair bone defects within orthopaedics, craniofacial surgery and dentistry. It is estimated that 2.2 million grafting procedures are performed annually worldwide [1] and maintain a market share of $7 billion in the United States alone [2]. There has been a considerable rise in the interest of using bioactive ceramic materials, such as hydroxyapatite and tricalcium phosphate (TCP), to serve as synthetic replacements for autogenous bone grafts, which suffer from donor site morbidity and limited supply [3]. These ceramic materials (which can be formed into three-dimensional scaffolds) are advantageous due to their inherent biocompatibility, osteoconductivy, osteogenecity and osteointegrity [2].

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Reddy, C. Mallikarjuna, B. Ram Bhupal Reddy, E. Kesava Reddy, and K. Sesha Maheswaramma. "Finite Element Modeling of Bone by Using Hydroxyapatite As Bioactive Nanomaterial in Bone Grafting, Bone Healing and the Reduction of Mechanical Failure in the Bone Surgery." In 2011 International Conference on Nanoscience, Technology and Societal Implications (NSTSI). IEEE, 2011. http://dx.doi.org/10.1109/nstsi.2011.6111995.

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I.Y., Bozo, Deev R.V., Presnyakov E.V., Bessonov V.B., Larionov I.A., and Baksheev I.K. "The Use of Microfocus X-Ray Tomography for the Characterization of Bone Regenerate in Jaw Biopsies After Bone Grafting." In 2023 Systems and Technologies of the Digital HealthCare (STDH). IEEE, 2023. http://dx.doi.org/10.1109/stdh59314.2023.10490662.

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Salaam, Amanee D., and Derrick Dean. "Electrospun Polycaprolactone-Nanodiamond Composite Scaffolds for Bone Tissue Engineering." In ASME 2010 First Global Congress on NanoEngineering for Medicine and Biology. ASMEDC, 2010. http://dx.doi.org/10.1115/nemb2010-13298.

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Every year, there are roughly 8 million bone fractures in United States [1]. In addition, approximately 2300 new cases of primary bone cancer are diagnosed each year [2]. Yet, the number of people suffering from bone disease is significantly greater; about 10 million people in the U.S. alone suffer from osteoporosis [3]. Consequently, surgeons perform nearly 500,000 bone graft operations annually making bone grafts the second most frequently transplanted materials [4]. Although there is an extremely high demand for treatment of bone abnormalities, the current grafting methods fail to meet these demands due to several limitations. Autografting has the fewest problems with rejection and pathogen transmission, however in some cases the availability may be limited or not be possible (e.g., genetic diseases). With other methods of transplantation such as allogafting and xenografting where tissue is acquired from other humans or species, respectively, the receptor’s immune system causes an increased risk of chronic rejection [5]. Notably, the major drawback with all these methods is that they often require multiple painful and invasive surgeries.

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Tandon, Rahul, and Alan S. Herford. "Future of bone pathology, bone grafting, and osseointegration in oral and maxillofacial surgery: how applying optical advancements can help both fields." In SPIE BiOS, edited by Nikiforos Kollias, Bernard Choi, Haishan Zeng, Hyun Wook Kang, Bodo E. Knudsen, Brian J. Wong, Justus F. Ilgner, et al. SPIE, 2013. http://dx.doi.org/10.1117/12.2001675.

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Ipsen, Brian J., John L. Williams, Michael J. Harris, and Thomas L. Schmidt. "Shear Strength of the Pig Capital Femoral Epiphyseal Plate: An Experimental Model for Human Slipped Capital Femoral Epiphysis Fixation Studies." In ASME 2002 International Mechanical Engineering Congress and Exposition. ASMEDC, 2002. http://dx.doi.org/10.1115/imece2002-32611.

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Slipped capital femoral epiphysis (SCFE) is the most common hip disorder affecting adolescent children [1]. The etiology is not fully understood but thought to be multifactorial, related to both biological and biomechanical factors [2]. SCFE occurs when the epiphysis of the proximal femur slips in relation to the metaphysis through the growth plate, causing pain, disability and potential long-term sequellae from joint incongruity. The treatment for SCFE typically involves some form of stabilization procedure using pins, screws, bone grafting, osteotomy, or casting.

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Slaoui, Idriss, Makeda K. Stephenson, Huma Abdul Rauf, Douglas E. Dow, and Sally S. Shady. "Stress Analysis of Bone Scaffold Designed for Segmental Bone Defects." In ASME 2015 International Mechanical Engineering Congress and Exposition. American Society of Mechanical Engineers, 2015. http://dx.doi.org/10.1115/imece2015-53398.

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Segmental bone defects result in isolated bone fragments. These defects may be caused by trauma or disease and are a leading cause for orthopedic surgery. Segmental defects pose a challenge as they contain gaps between the ends of bones, which are too large for the regenerating tissue to naturally bridge and repair. A widely used clinical approach to repair such defects is the use of autografts that provide the essential bone growth features. However, autografts generate a secondary deficit in the region from which the graft was harvested. This grafting procedure may result in other complications, such as infections, inflammation, scarring, and bleeding. Synthetic bone scaffolding has been explored as a viable method of helping the body repair segmental bone defects. While synthetic bone scaffolding is a promising approach in orthopedic treatments, limitations exist. Bone is a complex organ with many cell types, emergent, anisotropic, mechanical properties and molecular interactions. Studies have shown that the inner geometries, such as pore size, play an integral role in bone regeneration, cell proliferation, differentiation and recovery. An architecturally-based approach in the design and fabrication of the scaffold may support the differentiation of complex bone tissues. This study developed and tested scaffold designs having different pore size and beam thickness. The designs were developed and simulated for compression and tension in SolidWorks. A hexagonal unit cell was the basis for scaffold design. In one experimental trial (Group 1), the offset of the layers was varied. In another experimental trial (Group 2), the ratio between pore size and beam thickness was varied while using the optimal offset from the former trial. The material for simulation was poly-L-lactic (PLA) acid. In the analysis of the simulation results, the optimal layer offset configuration of 100%,50% in the positive x-y direction showed the lowest stress distribution for both compression and tensile simulations compared to the other offset configurations analyzed. In the second trial of Group 2 models, two models with pore size to beam thickness ratios (7:1 and 8:1) demonstrated low stress distribution under the simulated physiological environments. These results suggest that both models can potentially have different applications in the repair of segmental bone defects.

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Rapporti di organizzazioni sul tema "Bone-grafting"

Markel, Mark D. The Effect of Cementation and Autogenous Bone Grafting on Allograft Union and Incorporation. Fort Belvoir, VA: Defense Technical Information Center, May 1994. http://dx.doi.org/10.21236/ada280324.

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Markel, Mark D. The Effect of Cementation and Autogenous Bone Grafting on Allograft Union and Incorporation. Fort Belvoir, VA: Defense Technical Information Center, September 1994. http://dx.doi.org/10.21236/ada285630.

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Markel, Mark D. The Effect of Cementation and Autogenous Bone Grafting on Allograft Union and Incorporation. Fort Belvoir, VA: Defense Technical Information Center, January 1995. http://dx.doi.org/10.21236/ada291094.

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Markel, Mark D. The Effect of Cementation and Autogenous Bone Grafting on Allograft Union and Incorporation. Fort Belvoir, VA: Defense Technical Information Center, February 1994. http://dx.doi.org/10.21236/ada276464.

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Nugraha, Alexander Patera, Hui Yang, Junduo Chen, Kunhua Yang, Ploypim Kraisintu, Kyaw Zaww, Aobo Ma та ін. β-Tricalcium Phosphate as Alveolar Bone Grafting in Cleft Lip/Palate: A Systematic Review. INPLASY - International Platform of Registered Systematic Review and Meta-analysis Protocols, серпень 2023. http://dx.doi.org/10.37766/inplasy2023.8.0113.

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OKAY, ERHAN, KORHAN OZKAN, Keith Baldwin, Alexandre Arkader, and Souroush Baghdadi. The clinical outcomes and current evidence in the surgical treatment of extremity-located fibrous dysplasia. INPLASY - International Platform of Registered Systematic Review and Meta-analysis Protocols, May 2023. http://dx.doi.org/10.37766/inplasy2023.5.0020.

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Review question / Objective: What are clinical outcomes and current evidence in the surgical treatment of extremity-located fibrous dysplasia? Condition being studied: Fibrous dysplasia is the fibro-osseous lesion of tissue where normal bone tissue is replaced by collagen fibroblast and varying amounts of osteoid cells which is caused by GNAS gene mutation. Surgery aims to correct deformities and avoid limb length discrepancies in symptomatic cases. Available options include curettage, grafting, corrective osteotomies, and using fixation materials. There is a need for an optimal surgical treatment.

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Chen, Jiayi, and Yiping Lu. Clinical evaluation of maxillary sinus floor elevation with or without bone grafting: a systematic review and Meta-analysis. INPLASY - International Platform of Registered Systematic Review and Meta-analysis Protocols, May 2023. http://dx.doi.org/10.37766/inplasy2023.5.0067.

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Pluhar, Grace. Optimization of Soft Tissue Management, Spacer Design, and Grafting Strategies for Large Segmental Bone Defects using the Chronic Caprine Tibial Defect Model. Fort Belvoir, VA: Defense Technical Information Center, October 2014. http://dx.doi.org/10.21236/ada613146.

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Forsberg, Jonathan A. Optimization of Soft Tissue Management, Spacer Design, and Grafting Strategies For Large Segmental Bone Defects Using The Chronic Caprine Tibial Defect Model. Fort Belvoir, VA: Defense Technical Information Center, October 2014. http://dx.doi.org/10.21236/ada613641.

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Canellas, João Vitor, Luciana Drugos, Fabio Ritto, Ricardo Fischer, and Paulo Jose Medeiros. What grafting materials produce greater new bone formation in maxillary sinus floor elevation surgery? A systematic review and network meta-analysis protocol. INPLASY - International Platform of Registered Systematic Review and Meta-analysis Protocols, June 2020. http://dx.doi.org/10.37766/inplasy2020.6.0106.

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