Bibliografie tematiche / Bone and Bones – cytology

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Letteratura scientifica selezionata sul tema "Bone and Bones – cytology"

Autore: Grafiati
Pubblicato: 29 luglio 2024
Ultima modifica: 31 luglio 2024

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Articoli di riviste sul tema "Bone and Bones – cytology"

1

Paudel, S., P. Kayastha, P. Pokharel, A. Shah, RK Ghimire e MA Ansari. "Giant cell tumor of patella". Journal of Institute of Medicine Nepal 34, n. 3 (31 dicembre 2012): 58–60. http://dx.doi.org/10.59779/jiomnepal.479.

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Abstract (sommario):
Giant cell tumor of bone also known as osteoclastoma is a distinct clinical, roentgenographic and pathologic entity with specific characteristics. It is a benign but locally aggressive neoplasm of the epiphyseal or metaphyseal-epiphyseal region of long tubular bones extending to the articular surface. It usually occurs after skeletal maturation and is one of the rare bone tumors that more frequently affects women. We report here a case of giant cell tumor originating from the right patella diagnosed on fine needle aspiration cytology.
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Paudel, S., P. Kayastha, P. Pokhrel, A. Shah, RK Ghimire e MA Ansari. "Giant cell tumor of patella". Journal of Institute of Medicine Nepal 34, n. 3 (13 ottobre 2013): 58–60. http://dx.doi.org/10.3126/jiom.v34i3.8920.

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Abstract (sommario):
Giant cell tumor of bone also known as osteoclastoma is a distinct clinical, roentgenographic and pathologic entity with specific characteristics. It is a benign but locally aggressive neoplasm of the epiphyseal or metaphyseal-epiphyseal region of long tubular bones extending to the articular surface. It usually occurs after skeletal maturation and is one of the rare bone tumors that more frequently affects women. We report here a case of giant cell tumor originating from the right patella diagnosed on ne needle aspiration cytology. DOI: http://dx.doi.org/10.3126/joim.v34i3.8920 Journal of Institute of Medicine, December, 2012; 34:58-60
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3

Patel, Rushin P., Shakti Goel e Pankaj R. Patel. "Aneurysmal Bone Cyst of Clavicle in a Six-Year-Old Male Child". Journal of Medical Research and Innovation 1, n. 3 (16 luglio 2017): 31–36. http://dx.doi.org/10.15419/jmri.80.

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Aneurysmal Bone Cyst (ABCs) is a cystic expansile lesion which is usually found in solitary locations in the metaphysis of long bones. The most common locations of ABC are long bones of lower limbs. There is little knowledge about the presence of this tumor in Clavicle. Here we present a case of a six year old male child who presented with complaint of swelling in left shoulder for four months. There was a dilemma in the diagnosis of the swelling due to its unusual presentation and appearance. The Fine Needle Aspiration Cytology was also inconclusive. The diagnosis of ABC was made only by excision biopsy. The Clavicle regenerated to nearly normal anatomy at 15 weeks follow up period. The patient is asymptomatic now and is able to perform all daily activities without any restrictions. The uniqueness of this case lies in the fact that this is the first case where ABC has been reported in Clavicular region in young Asian male of less than 10 years age. Keywords: ABC, Bone tumor, Expansile lesion.
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4

Tiwari, Neema. "Imprint Cytology - A Primary Diagnostic Tool to Bone Marrow Pathology". Recent Advances in Pathology & Laboratory Medicine 5, n. 1 (14 maggio 2019): 6–8. http://dx.doi.org/10.24321/2454.8642.201902.

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5

T., Mitila, Lakshmi Priya Asokan e Vimal Chander. "Osteosarcoma: a fluid cytologic diagnosis". International Journal of Research in Medical Sciences 11, n. 4 (29 marzo 2023): 1376–79. http://dx.doi.org/10.18203/2320-6012.ijrms20230895.

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Abstract (sommario):
Osteosarcoma is the most common malignant bone tumor characterized by the formation of disorganized immature bone or osteoid tissue from mesenchymal tumor cells. It most commonly occurs in the appendicular skeleton involving the metaphysis of long bones. It is the third most common cancer in adolescence with an annual incidence of 5.6 cases per million children under the age of 15 years. Giant cell-rich osteosarcoma (GCRO) is an exceedingly rare histological variant of conventional primary osteosarcoma. It constitutes about 1%-3% of all osteosarcomas. A 20-year-old male presented with the complaints of pain and swelling over the right knee. Examination revealed a tender 15×10×8 cm swelling palpable on the distal femur. Radiological investigations showed features suggesting right femoral osteosarcoma in the meta-epiphyseal region. A core needle biopsy from the lesion was performed and 15 ml of fluid obtained from the biopsy site was sent for cytological examination, which showed features suggestive of osteosarcoma. Biopsy showed features of osteosarcoma probably of giant cell rich type confirming the fluid cytology findings. Cell block preparation also revealed giant cell predominance. Osteosarcoma is a bone tumor found in areas of rapid bone turnover, most commonly the distal femur and proximal tibia of adolescent patients. Cytology plays a vital role in diagnosing bone tumors, being a rapid, easy, and minimally invasive outpatient department procedure. Histopathology, since it gives a complete architectural pattern of tissue, remains the gold standard diagnostic tool.
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Chandra, Smita, Neeti Puri, Meena Harsh e Anil Kumar Juyal. "Cytological diagnosis of osteoblastoma of the talus: Case report with unusual presentation and diagnostic pitfalls". CytoJournal 15 (27 agosto 2018): 20. http://dx.doi.org/10.4103/cytojournal.cytojournal_39_17.

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Osteoblastoma is a rare bone tumor mostly affecting the young adults and commonly involving the spinal cord and long bones. Talus is the uncommon site of presentation, and if involved, then the neck is more commonly involved than the body of talus. The cytological diagnosis of osteoblastoma is limited, and to the best of our knowledge, its fine-needle aspiration (FNA) in the talus has still not been reported in the literature. The present case of osteoblastoma is, therefore, being reported due to the unusual presentation in elderly male in the body of talus and showing extensive involvement on X-ray. The case was initially diagnosed on FNA cytology excluding the possibility of giant-cell tumor and osteosarcoma. The case also highlights the importance of vigilant observation of subtle cytological features of this rare tumor which may be helpful in avoiding diagnostic pitfalls, especially at an uncommon site and with unusual presentation. An early precise diagnosis by cytology may be followed by appropriate treatment and thus avoiding any further complications.
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Tabarestani, Amirhossein, Masoud nejad, Mohammad Minaie, Sonia Sahvieh e Reza Nikzad. "A rare case report of extensive mandibular osteoma corrected by unilateral mandibulectomy: cytological, radiological, and pathological investigation". Open Veterinary Journal 13, n. 3 (2023): 382. http://dx.doi.org/10.5455/ovj.2023.v13.i3.16.

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Background: Osteoma is a benign bone tumor that rarely affects animals. The most common bones involved with this tumor included the mandible, maxillofacial bones, and nasal sinuses. Definitive diagnosis is based on pathology findings which allow for differentiation with other bone lesions. Case Description: The patient, a five-year-old intact male Mongrel dog presented with a huge mandibular mass that involved both the right and left mandible, and led to dental occlusion. The radiography was performed and depicted the intense mass with a well-demarcated edge, a short transitional zone between normal and abnormal bone, and a smooth rounded radiopaque appearance. The investigation according to the fine needle aspiration showed the presence of oval to spindle shape cells with poorly malignancy criteria, fatty cells, reactive osteoblasts and osteoclasts based on a population of spindle-shaped cells, and low numbers of degenerated neutrophils, bacteria, and few macrophages. Then, the radiographic assessments and cytology findings demonstrated the osteoma and referred for surgical intervention. A unilateral mandibulectomy was performed, and the lesion was send to the histopathology laboratory. The histopathology evaluation showed osteocyte proliferation without malignancy features. The osteoblast cells also showed no atypical proliferation that endorses the osteoma tumor. Conclusion: Although, mandibular and maxillofacial bone resection in small animals have different tolerations, this patient became a candidate for surgery for future better nutrition and prevention of facial deformity and dental malocclusion. Follow-up after osteoma is one of the most necessary post-operation treatments to check the regeneration of the mass. There are considerable data in this report that should regard this tumor as a possible differential diagnosis for mandibular tumors.
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Dmytrenko, D., N. Kozariychuk, O. Tsyhykalo e N. Kuzniak. "ONTOGENETIC TRANSFORMATIONS OF BONES OF THE HUMAN ORBIT". Neonatology, Surgery and Perinatal Medicine 14, n. 1(51) (8 aprile 2024): 99–107. http://dx.doi.org/10.24061/2413-4260.xiv.1.51.2024.14.

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Introduction. Elucidation of the sources of human orbital bones, clarifi cation of the sequence of their ossifi cation will allow to create a morphological basis for eff ective interpretation of the data of fetal condition monitoring, will contribute to early diagnosis of variants of the structure and possible malformations of the head, organ of vision and related structures.The aim of the study. The aim of this work was to fi nd out the sources of origin, the chronology of ossifi cation, the characteristics of age-related topographic and anatomical changes in the bones of the orbit.Material and methods. 18 series of histological sections of samples of human embryos and pre-fetuses at the age of 4-12 weeks of intrauterine development (4,0-80,0 mm parietal- coccygeal length) and samples of 12 fetuses at the age of 4-9 months of intrauterine development (130,0-450. 0 mm parietal- calcaneal length) using a complex of morphological research methods (anthropometry, morphometry, preparation of histological sections, dissection, three- dimensional reconstruction of series of histological sections and computer tomography, statistical analysis).The study was conducted in accordance with the main provisions of the European Union Convention on Human Rights andBiomedicine (1997), as well as the Helsinki Declaration on Ethical Principles of Medical Research Involving Human Subjects(1964-2008), EU Directive No. 609 (1986), Order of the Ministry of Health of Ukraine dated 23.09.2009 No. 690.The work was carried out within the framework of the initiative research work of the Department of Histology, Cytology andEmbryology of the Bukovinian State Medical University «Structural and functional peculiarities of tissues and organs in ontogenesis, regularities of variant, constitutional, sex and age-related and comparative human morphology». State registration number: 0121U110121. Deadlines: 01.2021-12.2025.The results. The fi rst signs of the appearance of ossifi cation centers around the main nervous and visceral contents of the rudiment of the orbit are determined in 6-week-old embryos in the form of seven cartilaginous bone models, and the fi rst centers of ossifi cation among the rudiments of bones participating in the formation of the orbit are found in the rudiment of the maxilla. In the 6th month of intrauterine development, the processes of ossifi cation of the frontal, sphenoid, ethmoid and maxillary bones begin. At the end of the 8th month of intrauterine development, due to the ossifi cation processes of the lesser wing of the sphenoid and frontal bones, the orbit acquires features of a defi nitive structure.From the beginning of the fetal period of human ontogenesis, ossifi cation of the structures of the sphenoid bone continues, which leads to morphological transformations of the orbit in 5-month fetuses – it is separated from the sphenopalatine and infratemporal fossa by a bone layer, the optic canal is formed, and in 6-month fetuses processes of ossifi cation of the frontal, sphenoid, ethmoid and maxillary bones, and Müller’s orbital muscle changes its structure into a fi brous one.The analysis of the age-related dynamics of the morphometric parameters of the orbit during the fetal period of intrauterine development made it possible to establish the peculiarities of changes in its diameter, circumference and area, which are expressed by mathematical functions: diameter of the orbit, mm = –0. 2285+0.4704*x; circumference of the orbit, mm = –0.2924+1.4595*x; area of the orbit, mm2 = –87.8597+8.0387*x, where x is the age of the human fetus in weeks.Conclusion. The critical periods of the development of the orbit are the 6th month of prenatal ontogenesis, during which there is an uneven growth rate of the horizontal size of the orbit in relation to the vertical one, and its shape returns to the mesoconchal, which was previously observed in fetuses, as well as the 8th month, during which the growth of all parameters of the orbit slows down due to intensive processes of organogenesis of its visceral structures.
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Dey, Biswajit, Jitendra Singh Nigam, Jyotsna Naresh Bharti, Ashok Singh e Vivek Nair. "Osteoarticular tuberculosis: A series of six cases diagnosed on fine-needle aspiration cytology". Cytojournal 19 (4 marzo 2022): 11. http://dx.doi.org/10.25259/cytojournal_22_2021.

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A few studies are dealing with the role of fine-needle aspiration cytology in diagnosing osteoarticular tuberculosis (TB). The present study was undertaken to study the cytomorphological features of six cases of osteoarticular TB throughout 1 year, diagnosed by fine-needle aspiration cytology. The Papanicolaou, Giemsa, Ziehl–Neelsen, and periodic acid–Schiff stains were used in each case. The sampled material was also cultured in Lowenstein– Jensen media for Mycobacterium species and polymerase chain reaction assay for Mycobacterium tuberculosis. Histopathological findings were correlated whenever available. There were four male and two female patients. The age of the patients ranged from 15 to 53 years, with a mean age of 37 years. Most cases involved small bones (4/6) and long bones of upper and lower limbs (2/6). Radiologically, the suspected lesions presented as osteolytic lesions, fractures, and joint destruction. The smears showed epithelioid cell granulomas in 5 out of 6 cases (83.3%), multinucleate and Langhans’ giant cells in 3 out of 6 cases (50%), and only necrosis in 1 case (16.7%). Inflammatory cells were seen in the background in 5 out of 6 cases (83.3%). AFB was positive in 3 cases (50%). Culture in Löwenstein–Jensen media, done in three cases, showed growth of M. tuberculosis. PCR showed positivity for M. tuberculosis in all six cases. Fine-needle aspiration cytology is an easy procedure that can be used for the diagnosis of osteoarticular tuberculosis. Cytomorphologically, smears show epithelioid cell granulomas, multinucleated and Langhan’s’ giant cells, and necrosis.
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Haque, Md Nizamul, ASM Jahangir Chowdhury e Md Yusuf Ali. "Adenoid Cystic Carcinoma of the Lacrimal Gland Metastasizing after a Short Followup to Multiple Distant Bones - a Case Report with a Review of the Literature". Faridpur Medical College Journal 10, n. 2 (7 novembre 2016): 84–86. http://dx.doi.org/10.3329/fmcj.v10i2.30277.

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Adenoid cystic carcinoma (ACC) of the lacrimal gland is a rare disease, but it is the most common malignant epithelial tumor of the lacrimal gland, with poor prognosis. ACC of the lacrimal gland is notorious for its slow growth and tendency to recur despite surgical therapy and following radiotherapy and/or chemotherapy. This tumor type occasionally metastasize via haematogenous spread to lungs, brain and bone in decreasing order of frequency. When it happens, metastases are always multiple and wide. We report a case of a 28-year young man followed in our Hospital with ACC of right lacrimal gland resected on April 2014 and treated with surgery followed by post-operative radiotherapy (50Gy total dose). After one years of follow-up, Positron Emission Tomography (PET) scan reported multiple lytic lesions in distant bones specially to multiple sites of vertebral column. Fine Needle Aspiration Cytology (FNAC) confirmed metastasis of ACC. No evidence of other loco-regional or distant metastasis were described. Patient was treated with chemotherapy. After treatment, patient is actually in close follow up.Faridpur Med. Coll. J. Jul 2015;10(2): 84-86
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Tesi sul tema "Bone and Bones – cytology"

1

Söderlund, Veli. "Combined radiology and cytology in the diagnosis of bone lesions : a study of 494 patients /". Stockholm, 2002. http://diss.kib.ki.se/2002/91-7349-353-8/.

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Chen, Jinbiao Prince of Wales Clinical School UNSW. "In vitro and in vivo bone formation - assessment and application". Awarded by:University of New South Wales. Prince of Wales Clinical School, 2006. http://handle.unsw.edu.au/1959.4/24922.

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Background: Bone-grafting materials are required in orthopaedic surgery to treat bone defects. Bone formation assessment is required for the development of new strategies and approaches and for quality assurance and quality control of currently available materials. Approaches to the assessment of bone formation are yet to be systematically established, quantified and standardized. Aims: the overall aim of this study was to establish a set of comprehensive quantitative approaches for the assessment of bone formation and to evaluate the role of osteoblastic cells, growth factors, and scaffolds on this process. Materials & methods: both in vitro and in vivo parameters for osteoblast phenotype and bone formation were tested in osteosarcoma cell lines, Saos-2 and U2OS cells, mesenchymal cell line, C2C12 cells, primary adipose derived stromal cells (ADSCs), platelet rich plasma (PRP), and morselized bone grafts. The in vitro parameters used were measurement of alkaline phosphatase (ALP) activity, detection of bone nodules and biomineralization, and quantification of immunocytochemistry and conventional RT-PCR of osteoblast genotyping. In vivo parameters involved ectopic bone formation in nude mice and nude rats and a tibial defect model in nude rats. Histomorphometric and quantitative immunohistochemical analyses were also performed. Results: The in vitro characterization and ectopic bone formation capabiltity of Saos-2 and U2OS cells have been established. Saos-2 cell line, which presents many osteoblast genotype and phenotype, is a stable positive control for both in vitro and in vivo bone formation assessments. The measurement of ALP activity in both solid and liquid phases has been standardized. Both the genotype and phenotype of osteoblast lineage cells has been quantitatively assessed during the capability testing of ADSCs and PRP. Quantitative assessment of new bone formation and related protein markers in vivo has been successfully established through the testing of the biological properties of gamma irradiated morselized bone grafts. Conclusion: A comprehensive knowledge of the assessment of bone regeneration and formation in vitro and in vivo has been integrated and developed through years of study. A whole set of in vitro and in vivo approaches for the assessment of bone formation has been modified and standardized to best suit the different clinical applications. This thesis provides an outline of both in vitro and in vivo bone formation assessment and their clinical applications.
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O'Shaughnessy, Margaret Clare. "Nitric oxide mediated effects on bone cells". Thesis, Imperial College London, 2001. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.367610.

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Toksvig-Larsen, Søren. "On bone cutting". Lund : University Dept. of Orthopedics, 1992. http://books.google.com/books?id=3JBsAAAAMAAJ.

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O'Connor, John C. "The role of the bone microenvironment in prostate cancer bone metastasis". Access to citation, abstract and download form provided by ProQuest Information and Learning Company; downloadable PDF file, 271 p, 2007. http://proquest.umi.com/pqdweb?did=1394657781&sid=14&Fmt=2&clientId=8331&RQT=309&VName=PQD.

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Aksoy, Ceren. "Characterization And Identification Of Human Mesenchymal Stem Cells At Molecular Level". Phd thesis, METU, 2012. http://etd.lib.metu.edu.tr/upload/12614272/index.pdf.

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Bone marrow mesenchymal stem cells (BM-MSCs) are pluripotent cells that can differentiate into a variety of non-hematopoietic tissues. They also maintain healthy heamatopoiesis by providing supportive cellular microenvironment into BM. In this thesis, MSCs were characterized in terms of their morphological, immunophenotypical and differentiation properties. Then, they were examined by attenuated total reflection-Fourier transform infrared (ATR-FTIR) spectroscopy together with hierarchical clustering, and FTIR microspectroscopy. In the first part of this study, global structural and compositional changes in BM-MSCs during beta thallasemia major (
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Parsamian, Gagik P. "Damage mechanics of human cortical bone". Morgantown, W. Va. : [West Virginia University Libraries], 2001. http://etd.wvu.edu/templates/showETD.cfm?recnum=2014.

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Thesis (Ph. D.)--West Virginia University, 2001.
Title from document title page. Document formatted into pages; contains xiii, 165 p. : ill. (some col.). Includes abstract. Includes bibliographical references (p. 146-165).
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Clarke, Damian F. "Histological and radiographic variation in the parietal bone in a cadaveric population /". Online version, 1987. http://bibpurl.oclc.org/web/23173.

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Harden, Fiona J. "Digging into bone : investigative studies into silicate-substituted hydroxyapatite, collagen molecules and bone properties". Thesis, University of Aberdeen, 2014. http://digitool.abdn.ac.uk:80/webclient/DeliveryManager?pid=211423.

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Investigations into silicate-substituted hydroxyapatite (Si-HA) were performed. The aqueous precipitation method produced phase pure Si-HA with modi cations to the method causing impurities in the material. A novel study using Raman spectroscopy followed the behaviour of the silicate ions and provided a new interpretation regarding silicate substitution. The silicate ions created interactions with hydroxyl ions, initially, which reduced upon sintering of the material. As the silicate ions do not behave inde- pendently in the HA structure initially, suggests that these interactions may contribute to the bioactivity of Si-HA. Also industrial aspects of Si-HA were investigated regarding the silicate reagent (TEOS). A small di erence of 1% in the percentage concentration of TEOS was not negligible and caused a decrease in the amount of silicate substituted into HA. Di erent brands and grades of TEOS did produce Si-HA with similar structural properties. Therefore, a variety of brands and grades of TEOS can be used and thus the most cost e ective choice can be made. The rst analytical investigations into the molecular arrangement of fully mineralised osteoarthritic (OA) and osteoporotic (OP) bone were performed through small angle neutron scattering (SANS) studies. This study provided a description for the molecular arrangement of collagen molecules, along the lateral plane, regarding the molecular di- ameter and the packing of these molecules into the bril by the development of a model based on SANS theory. The collagen molecules behave like a 2-dimensional liquid-like system. Through the development of the model, the rst written solution for the struc- ture factor for a system of hard-disks was stated. This study provided an understanding into how collagen molecules are arranged in OA and OP bone. Also, compositional studies iterated possible di erences between the organic content of OA and OP bone. Thus the organic content of bone may play a role in the bone disorders.
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Seigneurin, Daniel. "Cytologie quantitative de la maturation granulocytaire dans la moelle normale et au cours des syndromes myélodysplasiques". Grenoble 1, 1987. http://www.theses.fr/1987GRE10112.

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Libri sul tema "Bone and Bones – cytology"

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H, Helfrich Miep, e Ralston Stuart, a cura di. Bone research protocols. Totowa, N.J: Humana Press, 2003.

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R, Arnett Timothy, e Henderson Brian, a cura di. Methods in bone biology. London: Chapman & Hall, 1998.

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H, Helfrich Miep, e Ralston Stuart, a cura di. Bone research protocols. Totowa, N.J: Humana Press, 2003.

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4

Károly, Lapis, Eckhardt S e International Union Against Cancer, a cura di. Cytology, pathology, and cancer prognosis. Budapest: Akadémiai Kiadó, 1987.

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5

Westendorf, Jennifer J., e Andre J. Van Wijnen. Osteoporosis and osteoarthritis. New York: Humana Press, 2015.

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E, Lindh, e Thorell Jan I. 1934-, a cura di. Clinical impact of bone and connective tissue markers. London: Academic, 1989.

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7

W, Long Michael, e Wicha Max S, a cura di. The Hematopoietic microenvironment: The functional and structural basis of blood cell development. Baltimore: Johns Hopkins University Press, 1993.

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Dodd, Leslie. Atlas of soft tissue and bone pathology: With histologic, cytologic, and radiologic correlations. New York: Demos Medical, 2015.

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United States. National Aeronautics and Space Administration., a cura di. Studies of intercellular communication and intracellular metabolic responses by bone cells to simulated weightlessness: Final NASA report. [Washington, DC: National Aeronautics and Space Administration, 1997.

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1933-, Tavassoli Mehdi, a cura di. Handbook of the hemopoietic microenvironment. Clifton, N.J: Humana Press, 1989.

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Capitoli di libri sul tema "Bone and Bones – cytology"

1

Bui, Marilyn M., e Walid E. Khalbuss. "Utilizing Cytology as an Adjunct to Frozen Section to Enhance the Intraoperative Diagnosis of Bone and Soft Tissue Tumors". In Cytopathology of Soft Tissue and Bone Lesions, 205–22. Boston, MA: Springer US, 2010. http://dx.doi.org/10.1007/978-1-4419-6499-1_8.

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Caldarini, Carla, Paola Catalano, Valentina Gazzaniga, Silvia Marinozzi e Federica Zavaroni. "The Study of Ancient Bone Remains". In Bones, 3–38. Cham: Springer International Publishing, 2015. http://dx.doi.org/10.1007/978-3-319-19485-1_1.

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Lajara, Sigfred. "Bone". In Non-Neoplastic Cytology, 301–28. Cham: Springer International Publishing, 2023. http://dx.doi.org/10.1007/978-3-031-44289-6_17.

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Roberts, Anne, e Peter Gardiner. "Bone and Bones". In Systems of Life, 5–16. London: Macmillan Education UK, 1993. http://dx.doi.org/10.1007/978-1-349-13443-4_2.

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Adler, Claus-Peter. "Bones and Bone Tissue". In Bone Diseases, 1–11. Berlin, Heidelberg: Springer Berlin Heidelberg, 2000. http://dx.doi.org/10.1007/978-3-662-04088-1_1.

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Bartl, Reiner, e Christoph Bartl. "The Patient with “Dense Bones”". In Bone Disorders, 351–54. Cham: Springer International Publishing, 2016. http://dx.doi.org/10.1007/978-3-319-29182-6_61.

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Slootweg, Pieter. "Bone Tumors". In Pathology of the Maxillofacial Bones, 171–95. Cham: Springer International Publishing, 2015. http://dx.doi.org/10.1007/978-3-319-16961-3_9.

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Mays, Simon. "Bone disease". In The Archaeology of Human Bones, 181–217. 3a ed. Third edition. | New York : Routledge, 2021.: Routledge, 2021. http://dx.doi.org/10.4324/9781315171821-8.

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Mays, Simon. "Cremated bone". In The Archaeology of Human Bones, 312–32. 3a ed. Third edition. | New York : Routledge, 2021.: Routledge, 2021. http://dx.doi.org/10.4324/9781315171821-13.

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Domanski, Henryk A., Xiaohua Qian e Donald E. Stanley. "Bone". In Atlas of Fine Needle Aspiration Cytology, 599–652. Cham: Springer International Publishing, 2018. http://dx.doi.org/10.1007/978-3-319-76980-6_16.

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Atti di convegni sul tema "Bone and Bones – cytology"

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Abeed, Abrar Shahriar, Asif Atiq, Afra Antara Anjum, Azher Ahmed Efat e Dewan Ziaul Karim. "BoMaCNet: A Convolutional Neural Network Model to Detect Bone Marrow Cell Cytology". In 2022 25th International Conference on Computer and Information Technology (ICCIT). IEEE, 2022. http://dx.doi.org/10.1109/iccit57492.2022.10054976.

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Mehta, Bhavin V., e Robert J. Setlock. "Improved Prosthetic Bone Implants". In ASME 2003 International Mechanical Engineering Congress and Exposition. ASMEDC, 2003. http://dx.doi.org/10.1115/imece2003-43048.

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Abstract (sommario):
An improved method for manufacturing prosthetic bones is examined. We are developing a new improved method for designing and manufacturing prosthetic bones that have a porous interior core covered by a solid outer shell, more closely matching the morphology of natural bone. The new method is compatible with a wide variety of materials, including polymers, metals, composites, and biodegradable scaffold materials. Use of biodegradable scaffold material holds the potential for eventual bone regeneration within and throughout the prosthesis. Regardless of the material selection, this improved type of prosthesis is expected to more closely mimic the overall material and structural properties of natural bone, including shape, strength, weight, and weight distribution. By fabricating prosthetic bones that duplicate the material and structural properties of natural bone, implants could be made to operate as precision replacements, feeling and functioning exactly like natural bone. In addition to improving patient comfort, these new prostheses are expected to reduce the occurrence of unnatural secondary wear patterns caused by current style prosthetic bones that function in unnatural fashions due to their non-matching material and structural properties.
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Ramos-Homs, Amy. "Synthesis of Bone Scaffold for Pediatric Bone Defects Using 3D Printing". In MME Undergraduate Research Symposium. Florida International University, 2022. http://dx.doi.org/10.25148/mmeurs.010560.

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Pediatric bone defects, requiring surgical interventions and implants, include malignant and nonmalignant bone tumors and trauma fractures. Malignant bone tumors (MBT), such as Osteosarcoma and Ewing sarcoma, are aggressive primary cancers that affect growing adolescent bones (10- to 19-year-olds) and require complex reconstruction due to large bone excision during surgical interventions. Pediatric bone fractures requiring surgical interventions peak in 10- to 14-year-olds and are a major public health concern in the US with an impact on patients, parents, and healthcare costs of approx. 350 billion. These diseases require bone tissue replacement in changing bones. Bone reconstruction and medical implant design for growing pediatric bones have unique challenges due to active growth and there is a greater need for active, resorbable, and patient-specific implants to prevent growth impediments. The current available pediatric implant is limited in addressing these needs and is primarily addressed by static metallic implants designed for adults. We plan to work towards the design and synthesis of a bone scaffold by modifying a CAD model considering the size of the porosity in the structure of the pediatric bone. This modified model will be 3D printed and subjected to tests to evaluate the strength and composition of the scaffold. Afterwards, the scaffold is used for cell culture in hopes of eliciting cellular response for bone formation and cell regeneration, since a key factor to assess is whether the scaffold will grow with the bone, or the bone will grow with the scaffold. This is done to support the attachment of cells on the surface of the bone to actively support bone modeling processes under structural changes of growing bones.
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Cavazos, Omar, Maurizio Manzo, Erick Ramírez-Cedillo e Hector R. Siller. "Bone-Integrated Optical Microlasers for In-Vivo Diagnostic Biomechanical Performances". In ASME 2019 International Mechanical Engineering Congress and Exposition. American Society of Mechanical Engineers, 2019. http://dx.doi.org/10.1115/imece2019-11406.

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Abstract Bones experience mechanical loads on a daily basis. It is difficult to obtain biomechanical performances in-vivo measurements. When implants are integrated with bones after surgery, especially in aged individuals, their osseointegration can compromise the structural integrity of bones; for this reason, it is important to monitor the evolution of the mechanical properties of bones with some in-vivo diagnostic technique. In this study, we propose to integrate optical microsensing devices into bones. To simulate the working principle, a sensor is integrated with a 3-D printed bone. The sensing element is a dye-doped optical microlaser based on the morphology dependent resonance (MDR) shifts also called the whispering gallery mode phenomenon (WGM). When the microlaser is excited by a light source, the fluorescence from the dye couples with the optical resonances. These optical resonances are very sensitive to any perturbation of the microlasers’s morphology. Therefore, the local strain variation of the bone can be related to the shift of the optical resonances. This in-vivo technique monitors the biomechanical performance of bones with implants and prosthetics.
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Litniewski, J., L. Cieslik, M. Lewandowski, R. Tymkiewicz, B. Zienkiewicz e A. Nowicki. "Bone scanner for examination of deeply located trabecular bones". In 2011 IEEE International Ultrasonics Symposium (IUS). IEEE, 2011. http://dx.doi.org/10.1109/ultsym.2011.0117.

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Hoursan, Hesam, e Mohammad Taghi Ahmadian. "Dynamic Behaviour of Ox Tibial and Femoral Bones: A Comparison With Human Bones". In ASME 2015 International Design Engineering Technical Conferences and Computers and Information in Engineering Conference. American Society of Mechanical Engineers, 2015. http://dx.doi.org/10.1115/detc2015-46555.

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Finite element models have been widely employed in an effort to quantify the stress and strain distribution around human bones as well as implanted prostheses and to explore the influence of these distributions on their long-term stability. In order to provide meaningful predictions, such models must contain an appropriate reflection of mechanical properties. Detailed geometrical and density information is now readily available from CT scanning. However, there are still many complications regarding patient-specific geometrical differences and bone dynamic behavior in-vivo. Experimental studies on animal bones, due to their convenience and accessibility, have always played a key role in simulating human bone behavior. In current study, a modal experiment has been done on an ox femoral and tibial bones and the results have been compared with those reported from human bones. Results have been obtained in terms of natural frequencies of medio-lateral bending mode shapes and damping ratios, and compared with those obtained by some previous studies. The results suggest similar pattern in modal behavior, but considerable difference between natural frequencies due to geometrical differences. To consider structural damping ratios, due to existence of moisture and marrow in bone in-vivo, samples have been obtained few hours post-mortem and the ratio has been extracted for each natural frequency. Finally, conclusions have been made on the similarity of the models and how to improve the FE models of human tibial and femoral components.
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Murakami, Tamotsu, e Yuki Hamasaki. "Basic Study of Autologous-Bone-Replaceable Artificial Bone Fabrication With Porosity Distribution Using Electrolysis". In ASME 2010 International Design Engineering Technical Conferences and Computers and Information in Engineering Conference. ASMEDC, 2010. http://dx.doi.org/10.1115/detc2010-28645.

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Recently, the use of bioresorbable materials (e.g., β-tricalcium phosphate (β-TCP)) has enabled the development of autologous-bone-replaceable artificial bones that are degraded and resorbed, i.e., replaced with autologous bone, when placed inside the human body for a sufficiently long duration. Although such autologous-bone replaceability requires high porosity of the artificial bone to promote the ingression of blood vessels and cells, the high porosity reduces the mechanical strength, which leads to disadvantages such as possible fracture after bone substitution surgery. One solution to this problem is to optimally arrange low-porosity portions for mechanical strength and high-porosity portions for autologous-bone replaceability in solid artificial bones. Commercially available artificial bones typically have fixed shapes such as a rectangular parallelepiped or cylinder. The use of recent solid freeform fabrication technologies, however, has enabled solid artificial bones with various shapes to be customized for individual medical cases. In this paper, the authors propose a solid freeform fabrication method for autologous-bone-replaceable artificial bones with a porosity distribution. A β-TCP porous artificial bone can be fabricated by placing a slurry consisting of β-TCP powder, water, a peptization reagent and a frother in a mold, drying it to form a solid shape and then sintering it. This β-TCP slurry contains ammonium polyacrylate as the peptization reagent, which is an electrolyte, and ammonia, hydrogen and oxygen gases are produced from its electrolysis. The authors conceived the idea of controlling the foaming of the β-TCP slurry by electrolysis, and of designing and implementing a fabrication system consisting of a fine nozzle with a microscrew for extruding β-TCP slurry as a filament and electrodes for controlling the electrolysis of the slurry. Using this system, we can fabricate a solid shape by drawing two-dimensional sections with the slurry filament and stacking each section, and at the same time vary the porosity by controlling the electric current applied for the electrolysis of the slurry. Using the experimental system, three β-TCP porous samples (approximately 18mm × 18mm × 9mm) of high (71.8%), medium (59.5%) and low (54.6%) porosity are successfully fabricated by applying electric currents of 20mA, 10mA and 0mA, respectively. Then a β-TCP porous sample (approximately 40mm × 10mm × 10mm) with a gradient porosity distribution (from 72.3% to 56.1%) is successfully fabricated by varying the electric current from 0mA to 20mA in a continuous fabrication process. From these results, the authors confirm the efficacy and potential of the proposed approach.
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James, Thomas P., e Brendan A. Andrade. "Is Synthetic Composite Bone a Substitute for Natural Bone in Screw Bending Tests?" In ASME 2011 International Mechanical Engineering Congress and Exposition. ASMEDC, 2011. http://dx.doi.org/10.1115/imece2011-65498.

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Composite replica bones have been used extensively for biomechanical studies. These studies normally rely upon the overall tensile, compressive, and bending strength of large replica bones, such as the tibia and femur. In this study, highly localized behavior of composite bone was scrutinized by examining the material’s response to cortical screws in bending. Of interest was localized deformation of the composite material as compared to the response of natural bone under similar loading conditions. Cortical screw deflection in a laminated composite bone was compared to deflection in a bovine bone under quasi-static loading. The laminated composite bone consisted of short glass fiber reinforced epoxy as a cortical bone substitute, while polyurethane foam was used as a cancellous bone substitute. A new laser projection method was used to make comparative measurements of the slope of the screw head near to the applied load. Initial results indicate that composite bone is a reliable substitute for natural bone in quasi-static studies of cortical screw deflection.
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Sheehy, Eamon J., Tatiana Vinardell, Conor T. Buckley e Daniel J. Kelly. "Towards Engineering Whole Bones via Endochondral Ossification". In ASME 2013 Summer Bioengineering Conference. American Society of Mechanical Engineers, 2013. http://dx.doi.org/10.1115/sbc2013-14504.

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Tissue engineering applications aim to replace or regenerate damaged tissues through a combination of cells, three-dimensional scaffolds, and signaling molecules [1]. The endochondral approach to bone tissue engineering [2], which involves remodeling of an intermittent hypertrophic cartilaginous template, may be superior to the traditional intramembranous approach. Naturally derived hydrogels have been used extensively in tissue engineering applications [3]. Mesenchymal stem cell (MSC) seeded hydrogels may be a particularly powerful tool in scaling-up engineered endochondral bone grafts as the low oxygen conditions that develop within large constructs enhance in vitro chondrogenic differentiation and functional development [4]. A key requirement however, is that the hydrogel must allow for remodeling of the engineered hypertrophic cartilage into bone and also facilitate vascularization of the graft. The first objective of this study was to compare the capacity of different naturally derived hydrogels (alginate, chitosan, and fibrin) to generate in vivo endochondral bone. The secondary objective was to investigate the possibility of engineering a ‘scaled-up’ anatomically accurate distal phalange as a paradigm for whole bone tissue engineering.
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Shrivas, Nikhil V., Abhishek Kumar Tiwari, Rakesh Kumar, Dharmendra Tripathi e Vasu Raman Sharma. "Investigation on Loading-Induced Fluid Flow in Osteogenesis Imperfecta Bone". In ASME 2018 5th Joint US-European Fluids Engineering Division Summer Meeting. American Society of Mechanical Engineers, 2018. http://dx.doi.org/10.1115/fedsm2018-83496.

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Osteogenesis Imperfecta (OI) is a genetic bone disorder which is typically characterized by brittle bones with frequent fractures. It is also known as brittle bone disease. Surgical procedure is one of the ways adopted by clinicians for the management of OI. In recent years, it has however become clear that physical activity is equally important for managing OI in both children and adults. Exogenous mechanical stimulation e.g. prophylactic exercises may be useful in improving the bone mass and strength of OI bones as loading-induced mechanical components e.g. normal strain and canalicular fluid flow stimulate remodeling activities. Several studies have characterized the strain environment in OI bones, whereas, very few studies attempted to characterize the canalicular fluid flow. In the present study, we anticipate that canalicular fluid flow reduces in OI bone as compared to healthy bone under physiological loading. This work accordingly computes the canalicular fluid distribution in the single osteon model of OI and control/normal bones subjected to normal physiological loadings. A transversely isotropic poroelastic model of osteon is developed. Loading is applied in accordance with gait cycles reported for OI and healthy bones. Fluid distribution patterns computed for OI and healthy bones are compared at different time-points of stance phase of the gait cycle. A significant reduction in fluid flow is observed in case of OI bone as compared to healthy bone. This clearly indicates that improvements in physical activities or exercises can be designed to enhance the level of canalicular fluid flow to initiate possible osteogenic activities and the bone.
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Rapporti di organizzazioni sul tema "Bone and Bones – cytology"

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Брошко, Євгеній Олегович. Variability of Structural and Biomechanical Prameters of Pelophylax esculentus (Amphibia, Anura) Limb Bones. Vestnik zoologii, 2014. http://dx.doi.org/10.31812/0564/1529.

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Structural and biomechanical parameters of Edible Frog, Pelophylax esculentus (Linnaeus, 1758), limb bones, namely, mass, linear dimensions, parameters of the shaft ’s cross-sectional shape (cross-sectional area, moments of inertia, radiuses of inertia) were investigated. Some coeffi cients were also estimated: diameters ratio (df/ds), cross-sectional index (ik), principal moments of inertia ratio (Imax/Imin). Coeffi cients of variation of linear dimensions (11.9–20.0 %) and relative bone mass (22–35 %) were established. Moments of inertia of various bones are more variable (CV = 41.67–56.35 %) in relation to radii of inertia (CV = 9.68–14.67 %). Shaft ’s cross-sectional shape is invariable in all cases. However, there is high individual variability of structural and biomechanical parameters of P. esculentus limb bones. Variability of parameters was limited by the certain range.We suggest the presence of stable norm in bone structure. Stylopodium bones have the primary biomechanical function among the elements of limb skeleton, because their parameters most clearly responsiveto changes in body mass.
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Shevde-Samant, Lalita. Crosstalk Between Cancer Cells and Bones Via the Hedgehog Pathway Determines Bone Metastasis of Breast Cancer. Fort Belvoir, VA: Defense Technical Information Center, giugno 2008. http://dx.doi.org/10.21236/ada487471.

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Balaga, Dr Sai Krishna, Dr Amal PS, Dr Jayaram Jayaram e Dr Naveen Naveen. MANAGEMENT OF INFECTIVE NON UNION OF SHAFT OF LONG BONES WITH LIMB RECONSTRUCTION SYSTEM. World Wide Journals, febbraio 2023. http://dx.doi.org/10.36106/ijar/7305662.

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Background: Complex nonunions are difcult to manage due to the presence of infection, deformities, shortening, and multiple surgeries in the past. Ilizarov xation has traditionally been used to manage complex nonunions. The disadvantages of Ilizarov include poor patient compliance, frame inconvenience, and difcult frame construction. We studied ten long bone infective nonunions treated with the limb reconstruction system (LRS). Materials and methods : Between September 2020 and December 2022, we treated 10 cases of infective nonunion of long bone with the LRS. Patients were routinely followed up for 12 to 18 months and assessed both clinically and radiologically. Out of 10 cases we were able to achieve Results : : union in all cases. And eradication of infection in 90% of cases with no limb length discrepancy in any case. Bone results are excellent in 80% of cases and good in 20% of cases. Functional results are excellent in 80% of cases and good in 10% of cases, fair in 10% of cases. LRS is an alternati Conclusion : ve to the Ilizarov xation in their management of complex nonunion of long bones. It is less cumbersome to the patient and more surgeon and patient friendly.
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Tao, Yang, Victor Alchanatis e Yud-Ren Chen. X-ray and stereo imaging method for sensitive detection of bone fragments and hazardous materials in de-boned poultry fillets. United States Department of Agriculture, gennaio 2006. http://dx.doi.org/10.32747/2006.7695872.bard.

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Abstract (sommario):
As Americans become increasingly health conscious, they have increased their consumptionof boneless white and skinless poultry meat. To the poultry industry, accurate detection of bonefragments and other hazards in de-boned poultry meat is important to ensure food quality andsafety for consumers. X-ray imaging is widely used for internal material inspection. However,traditional x-ray technology has limited success with high false-detection errors mainly becauseof its inability to consistently recognize bone fragments in meat of uneven thickness. Today’srapid grow-out practices yield chicken bones that are less calcified. Bone fragments under x-rayshave low contrast from meat. In addition, the x-ray energy reaching the image detector varieswith the uneven meat thickness. Differences in x-ray absorption due to the unevenness inevitablyproduce false patterns in x-ray images and make it hard to distinguish between hazardousinclusions and normal meat patterns even by human visual inspection from the images.Consequently, the false patterns become camouflage under x-ray absorptions of variant meatthickness in physics, which remains a major limitation to detecting hazardous materials byprocessing x-ray images alone.Under the support of BARD, USDA, and US Poultry industries, we have aimed todeveloping a new technology that uses combined x-ray and laser imaging to detect bonefragments in de-boned poultry. The technique employs the synergism of sensors of differentprinciples and has overcome the deficiency of x-rays in physics of letting x-rays work alone inbone fragment detection. X-rays in conjunction of laser-based imaging was used to eliminatefalse patterns and provide higher sensitivity and accuracy to detect hazardous objects in the meatfor poultry processing lines.Through intensive research, we have met all the objectives we proposed during the researchperiod. Comprehensive experiments have proved the concept and demonstrated that the methodhas been capable of detecting frequent hard-to-detect bone fragments including fan bones andfractured rib and pulley bone pieces (but not cartilage yet) regardless of their locations anduneven meat thickness without being affected by skin, fat, and blood clots or blood vines.
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Riveros, Guillermo, Felipe Acosta, Reena Patel e Wayne Hodo. Computational mechanics of the paddlefish rostrum. Engineer Research and Development Center (U.S.), settembre 2021. http://dx.doi.org/10.21079/11681/41860.

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Purpose – The rostrum of a paddlefish provides hydrodynamic stability during feeding process in addition to detect the food using receptors that are randomly distributed in the rostrum. The exterior tissue of the rostrum covers the cartilage that surrounds the bones forming interlocking star shaped bones. Design/methodology/approach – The aim of this work is to assess the mechanical behavior of four finite element models varying the type of formulation as follows: linear-reduced integration, linear-full integration, quadratic-reduced integration and quadratic-full integration. Also presented is the load transfer mechanisms of the bone structure of the rostrum. Findings – Conclusions are based on comparison among the four models. There is no significant difference between integration orders for similar type of elements. Quadratic-reduced integration formulation resulted in lower structural stiffness compared with linear formulation as seen by higher displacements and stresses than using linearly formulated elements. It is concluded that second-order elements with reduced integration and can model accurately stress concentrations and distributions without over stiffening their general response. Originality/value – The use of advanced computational mechanics techniques to analyze the complex geometry and components of the paddlefish rostrum provides a viable avenue to gain fundamental understanding of the proper finite element formulation needed to successfully obtain the system behavior and hot spot locations.
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Clulow, F. V., T. P. Lim e N. K. Dave. Radionuclide levels and 226Ra concentration ratios between water, vegetation, and tissues of ruffed grouse (Bonasa umbellus) from a watershed with U tailings near Elliot Lake, Canada. Natural Resources Canada/CMSS/Information Management, 1989. http://dx.doi.org/10.4095/331773.

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Abstract (sommario):
Radionuclide levels measured in bone, muscle, kidney, and liver tissues, gut contents, and diet items of 47 grouse from the Serpent River drainage basin, containing U tailings at Elliot Lake, and from control areas in Ontario, showed variation by site and tissue. The mean level of 226Ra in bones of grouse sampled from Elliot Lake (28.5 mBq.g -1) was higher than that in bones of birds from a distant control site near Sudbury, Ontario (8.0 mBq.g -1), but similar to the value in a local control population (28.1 mBq.g -1). Birds from Mid- and Low-Serpent River basin populations (with 17.1 and 17.7 mBq.g-1 respectively) did not differ from local or distant control populations; muscle, liver, and kidney had lower 226Ra concentrations which did not differ significantly among populations. Levels of 226Ra in the crop contents and chyle did not differ significantly by site and were similar to those of food items consumed by the birds. Chyme values were higher in birds sampled in Elliot Lake and at the local control site than in those taken at the distant control site; birds sampled downstream from Elliot Lake did not differ from distant controls in this regard. Levels of 232Th, 236Th were below detection limits (0.1 gg.g-1 and 5.0 mBq.g-1 respectively) in bone, muscle, and liver tissue in two grouse with elevated levels of 226Ra. Other radionuclides were measurable in some tissues: 238U in bone at 0.4 gg.g-1 , in muscle to 0.2 gg.g -1 , in liver to 1.0 gg.g -1 ; 228Th was found only in muscle (8.0 mBq.g -1 ); 216Po was found in bone, muscle, and liver (maxima: 24.0, 7.0, 16.0 mBq.g-1 ) with the exception of one muscle sample; 216Pb was detected in only one liver sample (50.0 mBq.g -1 ). Environmental levels fell within ranges previously reported at the sites, or at similar locations elsewhere. Leaves of trembling and largetooth aspen growing in the basin had mean 226Ra levels of 41.8 and 52.7 mElq.g-1 (dry 215.4 mBq.g -1 (ai weight) respectively, fungal material caried up to r-dried), with some variation by site. River and lake waters sampled near the U tailings had 118.1 mBq.L -1- of dissolved 226Ra and at the distant control site the value was 12.1 mBq.L -1. The concentration ratios (CR) between bone of grouse collected at the Elliot Lake sites and trembling and largetooth aspen leaves were 1.38 and 1.09 (fresh weight basis); from other diet items and other tissues the values were less than unity. Water to tissue bone ratios, based on dissolved 226Ra levels (mBq.L -2) ranged to 144.08. People eating grouse from the study area are unlikely to consume radionuclides in excess of limits currently established by Canadian regulatory authorities.
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