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1

Chen, Chiu-Yu, Cara Bertozzi, Zhiying Zou, Lijun Yuan, John S. Lee, MinMin Lu, Stan J. Stachelek et al. "Blood flow reprograms lymphatic vessels to blood vessels". Journal of Clinical Investigation 122, n. 7 (2 luglio 2012): 2702. http://dx.doi.org/10.1172/jci65314.

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2

Chen, Chiu-Yu, Cara Bertozzi, Zhiying Zou, Lijun Yuan, John S. Lee, MinMin Lu, Stan J. Stachelek et al. "Blood flow reprograms lymphatic vessels to blood vessels". Journal of Clinical Investigation 122, n. 6 (1 giugno 2012): 2006–17. http://dx.doi.org/10.1172/jci57513.

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3

Lawson, Jeffrey. "Engineered Blood Vessels". Blood 130, Suppl_1 (7 dicembre 2017): SCI—12—SCI—12. http://dx.doi.org/10.1182/blood.v130.suppl_1.sci-12.sci-12.

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Abstract The field of tissue engineering has has made significant progress in the past 20 years. Of the many tissues and organs in development, the area of vascular tissue engineering is now one of the most mature. In that regard, we have developed a novel tissue engineered vascular graft (human acellular vessel [HAV]) that addresses many of the limitations of native vein harvest and the performance of both synthetic ePTFE and autologous vein grafts. The HAV is manufactured in a laboratory by culturing human vascular cells within a biodegradable scaffold that forms a mechanically robust tissue engineered blood vessel. The cells are then completely removed (decellularization), leaving behind a non-immunogenic human collagen-based vascular tissue that can be stored on the shelf for months at a time and ready for immediate implantation into any patient. The HAV is currently being evaluated in Phase II and Phase III clinical trials in the U.S., E.U. and Israel as an arteriovenous vascular access graft for hemodialysis in patients with end-stage renal failure and as an arterial substitute for patients in need of vascular bypass for peripheral arterial disease or vascular trauma. Following clinical implantation, we have observed repopulation and remodeling of the manufactured vessel with the hosts' own cells. We hypothesize that the biological composition of the HAV, compared to synthetic vascular grafts, promotes its physiological integration into host tissue including support of normal host cell infiltration and function. Host cells that identify histologically similar to vascular smooth muscle cells appear to repopulate the middle of the vessel and recipient cells characterized as endothelial cells appear to cover the luminal surface of the implanted vessel. Clinical observations of the Phase II trials have demonstrated excellent vessel durability and a freedom from both early and delayed infection. Based on the success of the Phase II studies, a Global Phase III study is underway for patients in need of dialysis access shunts and vascular programs for vascular (arterial) bypass and trauma are expanding. Disclosures Lawson: InnaVasc: Patents & Royalties; Humacyte, Inc.: Employment.
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4

Wong, W. "Broken Blood Vessels". Science Signaling 2, n. 57 (10 febbraio 2009): ec49-ec49. http://dx.doi.org/10.1126/scisignal.257ec49.

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5

Frederickson, Robert. "Rebuilding blood vessels". Nature Biotechnology 17, n. 11 (novembre 1999): 1051. http://dx.doi.org/10.1038/15025.

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Iruela-Arispe, M. Luisa. "LUMENating Blood Vessels". Developmental Cell 20, n. 4 (aprile 2011): 412–14. http://dx.doi.org/10.1016/j.devcel.2011.03.020.

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7

Hindson, Jordan. "Eternal blood vessels". Nature Reviews Materials 3, n. 5 (26 aprile 2018): 4. http://dx.doi.org/10.1038/s41578-018-0015-x.

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8

Lou, Kai-Jye. "Building blood vessels". Science-Business eXchange 7, n. 44 (novembre 2014): 1283. http://dx.doi.org/10.1038/scibx.2014.1283.

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9

Niu, Guoguang, Etai Sapoznik e Shay Soker. "Bioengineered blood vessels". Expert Opinion on Biological Therapy 14, n. 4 (25 gennaio 2014): 403–10. http://dx.doi.org/10.1517/14712598.2014.880419.

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10

Hendry, Charles, Alistair Farley e Ella McLafferty. "Blood vessels, circulation and blood pressure". Nursing Standard 27, n. 11 (14 novembre 2012): 35–40. http://dx.doi.org/10.7748/ns.27.11.35.s48.

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11

Travis, John. "Blood Vessels (Sans Blood) Shape Organs". Science News 160, n. 13 (29 settembre 2001): 198. http://dx.doi.org/10.2307/4012772.

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12

Hendry, Charles, Alistair Farley e Ella McLafferty. "Blood vessels, circulation and blood pressure". Nursing Standard 27, n. 11 (14 novembre 2012): 35–40. http://dx.doi.org/10.7748/ns2012.11.27.11.35.c9411.

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13

Pyatt, Lynette, e Roger Lock. "Modelling blood cells and blood vessels". Journal of Biological Education 27, n. 1 (marzo 1993): 10–11. http://dx.doi.org/10.1080/00219266.1993.9655295.

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14

Carey, Francis A., e Mary N. Sheppard. "Diseases of blood vessels". Surgery (Oxford) 39, n. 5 (maggio 2021): 241–47. http://dx.doi.org/10.1016/j.mpsur.2021.03.005.

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15

Nakagami, Hironori, e Ryuichi Morishita. "Aging of Blood Vessels". ANTI-AGING MEDICINE 5, n. 7 (2008): 73–77. http://dx.doi.org/10.3793/jaam.5.73.

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16

Barcia, Carlos. "Blood vessels and Parkinsonism". Frontiers in Bioscience 9, n. 1-3 (2004): 277. http://dx.doi.org/10.2741/1145.

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17

Folkman, Judah. "Addressing tumor blood vessels". Nature Biotechnology 15, n. 6 (giugno 1997): 510. http://dx.doi.org/10.1038/nbt0697-510.

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18

Niklason, Laura E., e Jeffrey H. Lawson. "Bioengineered human blood vessels". Science 370, n. 6513 (8 ottobre 2020): eaaw8682. http://dx.doi.org/10.1126/science.aaw8682.

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Abstract (sommario):
Since the advent of the vascular anastomosis by Alexis Carrel in the early 20th century, the repair and replacement of blood vessels have been key to treating acute injuries, as well as chronic atherosclerotic disease. Arteries serve diverse mechanical and biological functions, such as conducting blood to tissues, interacting with the coagulation system, and modulating resistance to blood flow. Early approaches for arterial replacement used artificial materials, which were supplanted by polymer fabrics in recent decades. With recent advances in the engineering of connective tissues, including arteries, we are on the cusp of seeing engineered human arteries become mainstays of surgical therapy for vascular disease. Progress in our understanding of physiology, cell biology, and biomanufacturing over the past several decades has made these advances possible.
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19

Benest, Andrew V., e Hellmut G. Augustin. "Blood vessels kept quiet". Nature 458, n. 7234 (marzo 2009): 41–42. http://dx.doi.org/10.1038/458041a.

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20

Abrahimi, P., R. Liu e J. S. Pober. "Blood Vessels in Allotransplantation". American Journal of Transplantation 15, n. 7 (23 marzo 2015): 1748–54. http://dx.doi.org/10.1111/ajt.13242.

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21

JONES, M. E., K. LADHANI, V. MUDERA, A. O. GROBBELAAR, D. A. MCGROUTHER e R. SANDERS. "Flexor Tendon Blood Vessels". Journal of Hand Surgery 25, n. 6 (dicembre 2000): 552–59. http://dx.doi.org/10.1054/jhsb.2000.0458.

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The aim of this study was to assess rabbit long flexor tendon vascularity in a qualitative and quantitative manner using immunohistochemistry. The endothelial cell surface marker CD31 was targeted with a specific monoclonal mouse-anti-human antibody with good species cross-reactivity. Subsequent signal amplification and chromogen labelling allowed vessel visualization. Computer image analysis was performed. Values for vessel number and total vessel area per section, as well as the sections’ cross-sectional tendon areas, were obtained. There was a consistent deep tendon avascular zone between the A2 and A4 pulley in the rabbit forepaw. This was not the case in the hindpaw, with dorsally orientated longitudinal vessels coursing the length of the intrasynovial tendon. The area of least vascularity in the hindpaw was around the metacarpophalangeal joint. We therefore recommend the use of hindpaw tendons when using the rabbit as a flexor tendon experimental model. This is because its vascular pattern is similar to that of the human flexor digitorum profundus.
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22

Hurtley, Stella M. "Remodeling senescent blood vessels". Science 369, n. 6506 (20 agosto 2020): 930.11–932. http://dx.doi.org/10.1126/science.369.6506.930-k.

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23

Carmeliet, Peter. "Creating unique blood vessels". Nature 412, n. 6850 (agosto 2001): 868–69. http://dx.doi.org/10.1038/35091178.

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24

Tozer, Gillian M., Chryso Kanthou e Bruce C. Baguley. "Disrupting tumour blood vessels". Nature Reviews Cancer 5, n. 6 (giugno 2005): 423–35. http://dx.doi.org/10.1038/nrc1628.

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25

Hughes, A. D., e M. Schachter. "Hypertension and blood vessels". British Medical Bulletin 50, n. 2 (1994): 356–70. http://dx.doi.org/10.1093/oxfordjournals.bmb.a072896.

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26

Lindop, George B. M. "Diseases of blood vessels". Surgery (Oxford) 27, n. 8 (agosto 2009): 313–19. http://dx.doi.org/10.1016/j.mpsur.2009.06.009.

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27

Sheppard, Mary N. "Diseases of blood vessels". Surgery (Oxford) 30, n. 8 (agosto 2012): 370–76. http://dx.doi.org/10.1016/j.mpsur.2012.05.017.

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28

Sheppard, Mary N. "Diseases of blood vessels". Surgery (Oxford) 33, n. 7 (luglio 2015): 295–301. http://dx.doi.org/10.1016/j.mpsur.2015.04.006.

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29

Carey, Francis A., e Mary N. Sheppard. "Diseases of blood vessels". Surgery (Oxford) 36, n. 6 (giugno 2018): 259–64. http://dx.doi.org/10.1016/j.mpsur.2018.03.011.

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30

Zarins, Christopher K., Charles A. Taylor e Thomas J. R. Hughes. "Modelling of Blood Vessels". Journal of Vascular and Interventional Radiology 8, n. 4 (luglio 1997): 713–15. http://dx.doi.org/10.1016/s1051-0443(97)70648-1.

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31

Wood, Jonathan. "Forming new blood vessels". Materials Today 9, n. 10 (ottobre 2006): 15. http://dx.doi.org/10.1016/s1369-7021(06)71644-3.

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32

Weinstein, Brant M. "Blood Vessels under Construction". Cell 111, n. 4 (novembre 2002): 456–58. http://dx.doi.org/10.1016/s0092-8674(02)01125-x.

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33

Queral, Luis A. "Diseases of blood vessels". Journal of Vascular Surgery 3, n. 6 (giugno 1986): A1. http://dx.doi.org/10.1016/s0741-5214(86)70013-x.

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34

Ryan, Terence J., e Sergio B. Curri. "Blood vessels and lymphatics". Clinics in Dermatology 7, n. 4 (ottobre 1989): 25–36. http://dx.doi.org/10.1016/0738-081x(89)90040-0.

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35

Millikan, Larry E. "Lymphatics and blood vessels". Clinics in Dermatology 29, n. 2 (marzo 2011): 226–30. http://dx.doi.org/10.1016/j.clindermatol.2010.09.013.

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36

Pries, Axel R., Bettina Reglin e Timothy W. Secomb. "Remodeling of Blood Vessels". Hypertension 46, n. 4 (ottobre 2005): 725–31. http://dx.doi.org/10.1161/01.hyp.0000184428.16429.be.

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37

Hoenig, Michel R., Gordon R. Campbell, Barbara E. Rolfe e Julie H. Campbell. "Tissue-Engineered Blood Vessels". Arteriosclerosis, Thrombosis, and Vascular Biology 25, n. 6 (giugno 2005): 1128–34. http://dx.doi.org/10.1161/01.atv.0000158996.03867.72.

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38

Carmeliet, Peter, e Edward M. Conway. "Growing better blood vessels". Nature Biotechnology 19, n. 11 (novembre 2001): 1019–20. http://dx.doi.org/10.1038/nbt1101-1019.

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39

Johnson, P. C., C. P. Cleary, J. L. Beggs, A. Olafsen e C. J. Watkins. "HUMAN TRANSPERINEURIAL BLOOD VESSELS". Journal of Neuropathology and Experimental Neurology 48, n. 3 (maggio 1989): 369. http://dx.doi.org/10.1097/00005072-198905000-00212.

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40

N R, Vaishnavi, Thrupthi S, Vaishnavi K, Yashaswini M C, Vandana C e Sowmya H. "Nanorobotics in Blood Vessels". International Journal of Engineering Research in Computer Science and Engineering 9, n. 10 (13 ottobre 2022): 32–36. http://dx.doi.org/10.36647/ijercse/09.10.art007.

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Nowadays the use of nanorobots for medical diagnostics is huge. Nanorobots are used to treat these diagnostics and it will be widely used in future. Here, we design a control method which controls the motion of Nanorobots that are sent into human’s blood vessels and it is used as medical therapies. This study investigates the control mechanism for locomotion of nanorobots in blood vessel repair applications. Each nanorobot operating as artificial platelets has only essential characteristics for self-assembling into a mass at the injured blood vessel to reduce blood loss.Electromagnetism can be used to guide the nanorobots to move to a particular point or part of the body. Coils are also used here.
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41

Queral, Luis A. "Diseases of blood vessels". Journal of Vascular Surgery 3, n. 6 (giugno 1986): 940. http://dx.doi.org/10.1016/0741-5214(86)90438-6.

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42

Abramson, David I. "Diseases of Blood Vessels". JAMA: The Journal of the American Medical Association 254, n. 14 (11 ottobre 1985): 2000. http://dx.doi.org/10.1001/jama.1985.03360140162051.

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43

Cummings, Michael. "Star Trek—from space vessels to blood vessels". Practical Diabetes International 20, n. 1 (gennaio 2003): 4–5. http://dx.doi.org/10.1002/pdi.451.

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44

Akhmetov, A. T., A. A. Valiev, A. A. Rakhimov, S. P. Sametov e R. R. Habibullina. "Microfluidics of blood in blood vessels stenosis". Proceedings of the Mavlyutov Institute of Mechanics 11, n. 2 (2016): 210–17. http://dx.doi.org/10.21662/uim2016.2.031.

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Abstract (sommario):
It is mentioned in the paper that hydrodynamic conditions of a flow in blood vessels with the stenosis are abnormal in relation to the total hemodynamic conditions of blood flow in a vascular system of a human body. A microfluidic device developed with a stepped narrowing for studying of the blood flow at abnormal conditions allowed to reveal blood structure in microchannels simulating the stenosis. Microstructure change is observed during the flow of both native and diluted blood through the narrowing. The study of hemorheological properties allowed us to determine an increasing contribution of the hydraulic resistance of the healthy part of the vessel during the stenosis formation.
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45

Frenette, Paul S., e Denisa D. Wagner. "Adhesion Molecules — Blood Vessels and Blood Cells". New England Journal of Medicine 335, n. 1 (4 luglio 1996): 43–45. http://dx.doi.org/10.1056/nejm199607043350108.

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46

Weiss, R. "Blood Vessels Support Engineered Implants". Science News 134, n. 11 (10 settembre 1988): 164. http://dx.doi.org/10.2307/3972727.

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47

Helmuth, Laura. "Drug Blockades Blood Vessels' Energy". Science News 155, n. 12 (20 marzo 1999): 183. http://dx.doi.org/10.2307/4011141.

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48

Mills, John A. "Inflammatory Diseases of Blood Vessels". Mayo Clinic Proceedings 77, n. 12 (dicembre 2002): 1399. http://dx.doi.org/10.4065/77.12.1398.

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49

Seiwerth, Sven, Luka Brcic, Lovorka Vuletic, Danijela Kolenc, Gorana Aralica, Marija Misic, Anita Zenko, Domagoj Drmic, Rudolf Rucman e Predrag Sikiric. "BPC 157 and Blood Vessels". Current Pharmaceutical Design 20, n. 7 (febbraio 2014): 1121–25. http://dx.doi.org/10.2174/13816128113199990421.

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50

Emmert, Maximilian Y. "Tissue engineered regenerating blood vessels". European Heart Journal 38, n. 41 (30 ottobre 2017): 3045–48. http://dx.doi.org/10.1093/eurheartj/ehx524.

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