Bibliografie tematiche / Biochemistry [mesh]

Letteratura scientifica selezionata sul tema "Biochemistry [mesh]"

Autore: Grafiati

Pubblicato: 26 luglio 2024

Ultima modifica: 27 luglio 2024

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Articoli di riviste sul tema "Biochemistry [mesh]"

Fielding, Andrew M., e Anne Powell. "Using Medline to achieve an evidence-based approach to diagnostic clinical biochemistry". Annals of Clinical Biochemistry: International Journal of Laboratory Medicine 39, n. 4 (1 luglio 2002): 345–50. http://dx.doi.org/10.1258/000456302760042461.

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Medline is the US National Library of Medicine database that is used for searching the medical biochemistry literature. The database is structured using medical subject subheadings (MeSH terms) to classify the content of references; indexing is done manually using MeSH terms as key words. Searching the database effectively means finding the maximum number of relevant references together with the minimum number of irrelevant ones. This article is aimed at explaining the limitations of Medline and suggesting some solutions to key problems. The goal is that users can improve their literature search technique by employing a structured approach. As usual, asking relevant questions before starting a search is essential.

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Uberoi, Pansy, Wai Lee, Alvaro Lucioni, Kathleen C. Kobashi e Una J. Lee. "Vaginal Mesh Survivorship". Current Bladder Dysfunction Reports 15, n. 2 (11 maggio 2020): 93–99. http://dx.doi.org/10.1007/s11884-020-00581-5.

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Birbilis, Th, E. Theodoropoulou, Ag Birbili, S. Dimas e V. Leutsakos. "A Preliminary Report on the Use of Relon Mesh in the Repair of Eventrations with Large Parietal Defects. An Experimental Study in Rats". Journal of International Medical Research 25, n. 3 (maggio 1997): 135–40. http://dx.doi.org/10.1177/030006059702500303.

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This experimental study in rats was designed to investigate the tolerability and the mode of healing when commercial relon mesh is used in the repair of large abdominal-wall defects. A defect was created to simulate anatomical derangement of the abdominal wall and a surgical correction was performed using relon mesh. The mesh was implanted intraperitoneally in 18 Wistar albino rats. The animals were killed under anaesthesia 4, 6, 8, 12, 15 or 30 days later and the intra-abdominal viscera were examined macroscopically for adhesions and other evidence of inflammatory reactions. Skin healing usually occurred within 7 — 8 days of surgery. Microscopic studies were used to confirm the gross findings and showed that maturation of granulation tissue, fibrocyte invasion with encapsulation of the mesh and the appearance of newly formed vessels occurred 2 weeks after surgery. Within 4 weeks a strong layer of connective tissue was present. The relon mesh was tolerated well. These results indicate that the use of relon mesh may provide a cheap alternative means of repairing large abdominal-wall defects.

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Seifalian, Amelia, Zeinab Basma, Alex Digesu e Vikram Khullar. "Polypropylene Pelvic Mesh: What Went Wrong and What Will Be of the Future?" Biomedicines 11, n. 3 (1 marzo 2023): 741. http://dx.doi.org/10.3390/biomedicines11030741.

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Background: Polypropylene (PP) pelvic mesh is a synthetic mesh made of PP polymer used to treat pelvic organ prolapse (POP). Its use has become highly controversial due to reports of serious complications. This research critically reviews the current management options for POP and PP mesh as a viable clinical application for the treatment of POP. The safety and suitability of PP material were rigorously studied and critically evaluated, with consideration to the mechanical and chemical properties of PP. We proposed the ideal properties of the ‘perfect’ synthetic pelvic mesh with emerging advanced materials. Methods: We performed a literature review using PubMed/Medline, Embase, Cochrane Library (Wiley) databases, and ClinicalTrials.gov databases, including the relevant keywords: pelvic organ prolapse (POP), polypropylene mesh, synthetic mesh, and mesh complications. Results: The results of this review found that although PP is nontoxic, its physical properties demonstrate a significant mismatch between its viscoelastic properties compared to the surrounding tissue, which is a likely cause of complications. In addition, a lack of integration of PP mesh into surrounding tissue over longer periods of follow up is another risk factor for irreversible complications. Conclusions: PP mesh has caused a rise in reports of complications involving chronic pain and mesh exposure. This is due to the mechanical and physicochemical properties of PP mesh. As a result, PP mesh for the treatment of POP has been banned in multiple countries, currently with no alternative available. We propose the development of a pelvic mesh using advanced materials including emerging graphene-based nanocomposite materials.

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Lin, Chia-Ju, Chih-Ku Liu, Hsiao-Yun Hsieh, Ming-Jer Chen e Ching-Pei Tsai. "Modified Vaginal Mesh Procedure with DynaMesh®-PR4 for the Treatment of Anterior/Apical Vaginal Prolapse". Diagnostics 13, n. 18 (18 settembre 2023): 2991. http://dx.doi.org/10.3390/diagnostics13182991.

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(1) Background: Treating female pelvic organ prolapse (POP) is challenging. Surgical meshes have been used in transvaginal surgeries since the 1990s, but complications such as mesh exposure and infection have been reported. Polyvinylidene fluoride (PVDF) mesh, known for its stability and non-reactive properties, has shown promise in urogynecological surgeries. (2) Methods: A retrospective analysis was conducted on 27 patients who underwent a modified PVDF vaginal mesh repair procedure using DynaMesh®-PR4 and combined trans-obturator and sacrospinous fixation techniques. Additional surgeries were performed as needed. (3) Results: The mean operation time was 56.7 min, and the mean blood loss was 66.7 mL. The average hospitalization period was 4.2 days with Foley catheter removal after 2 days. Patients experienced lower pain scores from the day of the operation to the following day. Postoperative follow-up revealed that 85.2% of patients achieved anatomic success, with 14.8% experiencing recurrent stage II cystocele. No recurrence of apical prolapse was observed. Complications were rare, with one case (3.7%) of asymptomatic mesh protrusion. (4) Conclusions: The modified vaginal mesh procedure using DynaMesh®-PR4 showed favorable outcomes with a short operation time, low recurrence rate, rare complications, and improved functional outcomes. This surgical option could be considered for anterior and apical pelvic organ prolapse in women.

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Palmer, Cristina J., e Gamal Ghoniem. "Management of Mesh-Related Pelvic Inflammation". Current Bladder Dysfunction Reports 13, n. 4 (26 settembre 2018): 201–5. http://dx.doi.org/10.1007/s11884-018-0489-9.

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Xie, Hualong, Yuqing Feng, Qunfeng Bi, Xiaofei Ma e Junfeng Zhao. "Biomimetic Design of a New Semi-Rigid Spatial Mesh Antenna Reflector". Biomimetics 9, n. 2 (25 gennaio 2024): 74. http://dx.doi.org/10.3390/biomimetics9020074.

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The reflective surface accuracy (RSA) of traditional space mesh antennas typically ranges from 0.2 to 6 mmRMS. To improve the RSA, an active control scheme can be employed, although it presents challenges in determining the installation position of the actuator. In this study, we propose a novel design for a semi-rigid cable mesh that combines rigid members and a flexible woven mesh, drawing inspiration from both rigid ribbed antennas and biomimicry. Initially, we investigate the planar mesh topology of spider webs and determine the bionic cable surface’s mesh topology based on the existing hexagonal meshing method, with RSA serving as the evaluation criterion. Subsequently, through motion simulations and careful observation, we establish the offset angle as the key design parameter for the bionic mesh and complete the design of the bionic cable mesh accordingly. Finally, by analyzing the impact of the node quantity on RSA, we determine a layout scheme for the flexible woven mesh with a variable number of nodes, ultimately settling for 26 nodes. Our results demonstrate that the inclusion of numerous rigid components on the bionic cable mesh surface offers viable installation positions for the actuator of the space mesh antenna. The reflector accuracy achieved is 0.196 mmRMS, slightly surpassing the lower limit of reflector accuracy observed in most traditional space-space mesh antennas. This design presents a fresh research perspective on combining active control schemes with reflective surfaces, offering the potential to enhance the RSA of traditional rigid rib antennas to a certain extent.

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Oda, Tetsuya. "A Delaunay Edges and Simulated Annealing-Based Integrated Approach for Mesh Router Placement Optimization in Wireless Mesh Networks". Sensors 23, n. 3 (17 gennaio 2023): 1050. http://dx.doi.org/10.3390/s23031050.

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Wireless Mesh Networks (WMNs) can build a communications infrastructure using only routers (called mesh routers), making it possible to form networks over a wide area at low cost. The mesh routers cover clients (called mesh clients), allowing mesh clients to communicate with different nodes. Since the communication performance of WMNs is affected by the position of mesh routers, the communication performance can be improved by optimizing the mesh router placement. In this paper, we present a Coverage Construction Method (CCM) that optimizes mesh router placement. In addition, we propose an integrated optimization approach that combine Simulated Annealing (SA) and Delaunay Edges (DE) in CCM to improve the performance of mesh router placement optimization. The proposed approach can build and provide a communication infrastructure by WMNs in disaster environments. We consider a real scenario for the placement of mesh clients in an evacuation area of Kurashiki City, Japan. From the simulation results, we found that the proposed approach can optimize the placement of mesh routers in order to cover all mesh clients in the evacuation area. Additionally, the DECCM-based SA approach covers more mesh clients than the CCM-based SA approach on average and can improve network connectivity of WMNs.

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Zubair, Mohammed, Mohammed Zulkifly Abdullah e Kamarul Arifin Ahmad. "Hybrid Mesh for Nasal Airflow Studies". Computational and Mathematical Methods in Medicine 2013 (2013): 1–7. http://dx.doi.org/10.1155/2013/727362.

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The accuracy of the numerical result is closely related to mesh density as well as its distribution. Mesh plays a very significant role in the outcome of numerical simulation. Many nasal airflow studies have employed unstructured mesh and more recently hybrid mesh scheme has been utilized considering the complexity of anatomical architecture. The objective of this study is to compare the results of hybrid mesh with unstructured mesh and study its effect on the flow parameters inside the nasal cavity. A three-dimensional nasal cavity model is reconstructed based on computed tomographic images of a healthy Malaysian adult nose. Navier-Stokes equation for steady airflow is solved numerically to examine inspiratory nasal flow. The pressure drop obtained using the unstructured computational grid is about 22.6 Pa for a flow rate of 20 L/min, whereas the hybrid mesh resulted in 17.8 Pa for the same flow rate. The maximum velocity obtained at the nasal valve using unstructured grid is 4.18 m/s and that with hybrid mesh is around 4.76 m/s. Hybrid mesh reported lower grid convergence index (GCI) than the unstructured mesh. Significant differences between unstructured mesh and hybrid mesh are determined highlighting the usefulness of hybrid mesh for nasal airflow studies.

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Tang, Jiawei, Mingyang Lu, Yuedong Xie e Wuliang Yin. "A Novel Efficient FEM Thin Shell Model for Bio-Impedance Analysis". Biosensors 10, n. 6 (17 giugno 2020): 69. http://dx.doi.org/10.3390/bios10060069.

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In this paper, a novel method for accelerating eddy currents calculation on a cell model using the finite element method (FEM) is presented. Due to the tiny thickness of cell membrane, a full-mesh cell model requires a large number of mesh elements and hence intensive computation resources and long time. In this paper, an acceleration method is proposed to reduce the number of mesh elements and therefore reduce the computing time. It is based on the principle of replacing the thin cell membrane with an equivalent thicker structure. The method can reduce the number of mesh elements to 23% and the computational time to 17%, with an error of less than 1%. The method was verified using 2D and 3D finite element methods and can potentially be extended to other thin shell structures. The simulation results were validated by measurement and analytical results.

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Più fonti

Tesi sul tema "Biochemistry [mesh]"

Martin, Lesley-Ann. "Early detection of resistance to meth benzimidazol-2YL- carbamate (MBC)". Thesis, University of Reading, 1992. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.333544.

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Schmitz, Gabriela Justamante Handel. "Análise comparativa dos proteomas das raízes tuberosas de mandioca (Manihot esculenta Crantz) de variedades de mesa e indústria". Universidade de São Paulo, 2013. http://www.teses.usp.br/teses/disponiveis/9/9131/tde-28082015-154641/.

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A mandioca (Manihot esculenta Crantz) é uma das principais culturas do mundo, havendo grande variabilidade genética. As variedades são classificadas com base na palatabilidade e toxicidade das raízes, em mansas ou doces e bravas ou amargas. Apesar da importância, o potencial da mandioca é pouco explorado, não sendo conhecidos, em nível molecular, os elementos determinantes para as suas características. Assim, pretendeu-se identificar, empregando a 2D-PAGE, proteínas que possam estar associadas com as diferenças físico-químicas das raízes tuberosas de variedades de mesa (IAC 576-70 e IAC 06-01), indústria (Cigana Preta, IAC 12 e IAC 90) e de uso misto (Vassourinha Paulista). Após extração de proteínas e separação por 2D-PAGE, as imagens dos géis foram analisadas no programa Delta2D (DECODON), sendo realizada análise estatística utilizando-se ANOVA (p<0,01), Heat Map e Análises de Componentes Principais (ACP) e de Agrupamentos. Os 146 spots de interesse foram removidos dos géis e suas proteínas digeridas e sequenciadas por espectrometria de massas. Algumas proteínas refletiram as características fenotípicas das variedades em estudo, especialmente entre as de mesa e indústria. Pela ACP, foram explicados 54,54% da variabilidade entre as amostras. A primeira componente separou as variedades exclusivamente de mesa de todas as demais, enquanto a segunda separou a IAC 90 de todas as outras, sendo esta caracterizada por um perfil proteico diferente das demais amostras de uso industrial. A IAC 576-70 e a IAC 12 apresentaram alta correlação positiva, assim como, a Vassourinha e a Cigana. A Análise de Agrupamentos corroborou as informações da ACP, revelando que o proteoma das raízes tuberosas refletiu diferenças fenotípicas entre as variedades.
Cassava (Manihot esculenta Crantz) is a main crop with large genetic variability. The varieties are classified according palatability and toxicity of the roots as sweet or bitter cassavas. Despite its importance, little is known about the molecular basis of phenotypic characteristics. Therefore, this study aimed to identify proteins associated to the differences between the sweet (\'IAC 576-70\' e \'IAC 06-01\'), bitter (\'Cigana Preta\', \'IAC 12\' e \'IAC 90\') and the mixed-use (\'Vassourinha Paulista\') varieties by 2D-PAGE. After the protein extraction and separation by 2D-PAGE, the gel images were analyzed through the software Delta 2D (DECODON), and the statistical analysis were performed with ANOVA (p<0,01), Heat Map, Principal Component Analysis (PCA) and Cluster Analysis. The 146 significant spots were removed from the gels, digested and sequenced by mass spectrometry. Some proteins were related to the physico-chemical characteristics of the varieties, especially between the sweet and the bitter. Variability of the samples was explained at the level of 54,54% by the PCA. The first component separated the sweet varieties from all others while the second one separated the \'IAC 90\' from all others. This variety was characterized by a different protein profile among the bitter cassavas. The \'IAC 576-70\' and the \'IAC 12\' were positively correlated, as well as, \'Vassourinha\' and the \'Cigana\'. Cluster Analysis agreed the PCA information, revealing that the proteomes of the tuberous roots reflected phenotypic differences among the varieties.

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Libri sul tema "Biochemistry [mesh]"

S, Monk Paul M., e Bradshaw Tony, a cura di. Chemistry for the biosciences. Oxford: Oxford University Press, 2006.

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W, Thorner Jeremy, Emr Scott e Abelson John, a cura di. Applications of chimeric genes and hybrid proteins. San Diego, CA: Academic Press, 2000.

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Chemistry for the Biosciences: The Essential Concepts. Oxford University Press, 2014.

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(Editor), Melvin I. Simon, Jeremy Thorner (Editor), Scott D. Emr (Editor) e John N. Abelson (Editor), a cura di. Applications of Chimeric Genes and Hybrid Proteins, Part B: Cell Biology and Physiology (Methods in Enzymology, Volume 327) (Methods in Enzymology). Academic Press, 2000.

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Fersht, Alan, e Fersht. Enzyme Struct and Mech 2e (Ise: Man Made Univ, 3/E, I/M. 2^a ed. W.H. Freeman & Company, 1985.

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Loren, Emma. Don't Mess with Me, I Am a Clinical Biochemist: 6X9 Career Pride 120 Pages Writing Notebooks. Independently Published, 2019.

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Capitoli di libri sul tema "Biochemistry [mesh]"

Mahendran, Gowthami, e Margaret A. Schwarz. "Emerging Hallmarks of Mitochondrial Biochemistry in Cardiac Trabecular Morphogenesis and Left Ventricular Noncompaction (LVNC)". In New Insights on Cardiomyopathy [Working Title]. IntechOpen, 2022. http://dx.doi.org/10.5772/intechopen.109098.

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Functioning as a pivotal platform for energy production and transduction, mitochondria generate ATP to meet the dynamic demands of embryonic development. Consequently, disruption or alteration in mitochondrial activity influences not only cellular status, but also can impact organ formation. Disrupted mitochondrial performance not only impairs cardiovascular function but can also disrupt cardiac maturation through prevention of the myocardium’s transition between the trabeculation to the compaction phase. During embryonic development, proliferating cardiomyocytes create a trabecular mesh network. Gradual compaction of this network transforms the intra-trabecular spaces into the capillaries of the coronary circulation. Achievement of functional compaction and ultimately normal cardiac function is dependent in part on mitochondrial well-being with failure to complete remodeling of the inner trabecular layer contributing to disrupted endocardial vasculature and fibrosis, left ventricular noncompaction (LVNC). LVNC, commonly associated with mitochondrial genetic alterations, is speculated to occur due to an interruption during the process of compaction at the early developmental stages of the left ventricle (LV). Mitochondrial mutations, remain the common etiology of LVNC with a wide spectrum of these genes associated with other cardiomyopathies related to LVNC. Understanding the impact that mitochondrial genetic alterations have on the evolution of cardiac noncompaction could provide new treatment opportunities.

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Lancelot, Christiane, e Veronique Rousseau. "Ecology of Phaeocystis: the key role of colony forms". In The Haptophyte Algae, 229–46. Oxford University PressOxford, 1994. http://dx.doi.org/10.1093/oso/9780198577720.003.0012.

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Abstract Species of Phaeocystis exhibit phase alternation between individual cells and gelatinous colonies. They regularly form dense, nearly specific blooms, in very contrasting nutrient-rich areas of the world’s oceans. The uniqueness of this genus of marine phytoplankters rests not only in its ubiquity but mostly in its peculiar physiology and ecology. No other marine phytoplankter has ever been shown to dominate an entire ecosystem; no other marine species distinguishes itself by a complex polymorphic life cycle that induces dramatic changes in the structure and functioning of planktonic and benthic food-webs as well as in the biogeochemistry of trace elements. The main features of the ecology of Phaeocystis-dominated ecosystems are analysed with regard to the Phaeocystis life cycle, and to recent data on the biochemistry and nutrient (major and trace element) metabolism of the different morphological forms that succeed each other during Phaeocystis bloom development, in relationship to the behaviour of bacteria and micro-, mesa-, and meta-zooplankton and the physical structure of the marine habitat. Particular emphasis is given to the biological functioning of Phaeocystis colonies that constitute by far the most important morphological forms in natural environments, as determined from the analysis of the structure and function of the mucilaginous matrix embedding the cells. Evidence is presented that the most remarkable ecological and biogeochemical properties of Phaeocystis-dominated ecosystems are attributable to the capacity of Phaeocystis colonial cells to synthesize, in nutrient-deprived conditions, exopolysaccharides capable of gelation.

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