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Letteratura scientifica selezionata sul tema "Assisted evolution"

Autore: Grafiati

Pubblicato: 14 settembre 2024

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Articoli di riviste sul tema "Assisted evolution"

Qiu, Yuchi, Jian Hu e Guo-Wei Wei. "Cluster learning-assisted directed evolution". Nature Computational Science 1, n. 12 (dicembre 2021): 809–18. http://dx.doi.org/10.1038/s43588-021-00168-y.

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Boland, James P., Roberto E. Kusminsky, E. H. Tiley e J. P. Tierney. "Evolution of Hand-Assisted Laparoscopic Surgery". Journal of Endourology 19, n. 2 (marzo 2005): 133–35. http://dx.doi.org/10.1089/end.2005.19.133.

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Orvieto, M. A., e V. R. Patel. "Evolution of Robot-Assisted Radical Prostatectomy". Scandinavian Journal of Surgery 98, n. 2 (giugno 2009): 76–88. http://dx.doi.org/10.1177/145749690909800203.

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Jewel, Delilah, Quan Pham e Abhishek Chatterjee. "Virus-assisted directed evolution of biomolecules". Current Opinion in Chemical Biology 76 (ottobre 2023): 102375. http://dx.doi.org/10.1016/j.cbpa.2023.102375.

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Molvar, Christopher, e Mihir Patel. "Evolution of Retrograde Transvenous Obliteration Techniques". Seminars in Interventional Radiology 35, n. 03 (agosto 2018): 185–93. http://dx.doi.org/10.1055/s-0038-1660796.

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AbstractGastric variceal hemorrhage is a life-threatening complication of portal hypertension with a poorer prognosis compared with esophageal variceal hemorrhage. The presence of an infradiaphragmatic portosystemic shunt, often a gastrorenal shunt, allows for treatment with retrograde transvenous obliteration (RTO). RTO is an evolving treatment strategy, which includes balloon-assisted RTO, plug-assisted RTO, and coil-assisted RTO, for both gastric variceal hemorrhage and hepatic encephalopathy. RTO techniques are less invasive than transjugular intrahepatic portosystemic shunt creation, with the benefit of improved hepatic function, but at the expense of increased portal pressure. This article discusses the techniques of RTO, including patient eligibility, as well as technical and clinical outcomes, including adverse events.

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Chen, Lisong, e Jianlin Shi. "Chemical-assisted hydrogen electrocatalytic evolution reaction (CAHER)". Journal of Materials Chemistry A 6, n. 28 (2018): 13538–48. http://dx.doi.org/10.1039/c8ta03741h.

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Schlipf, David, Florian Haizmann, Nicolai Cosack, Tom Siebers e Po Wen Cheng. "Detection of Wind Evolution and Lidar Trajectory Optimization for Lidar-Assisted Wind Turbine Control". Meteorologische Zeitschrift 24, n. 6 (5 novembre 2015): 565–79. http://dx.doi.org/10.1127/metz/2015/0634.

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Cai, Yiqiao, Chi Shao, Huizhen Zhang, Shunkai Fu, Hui Tian e Yonghong Chen. "A Neighborhood-Assisted Framework for Differential Evolution". IEEE Access 7 (2019): 44338–58. http://dx.doi.org/10.1109/access.2019.2908660.

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Trevathan, Wenda R. "The Evolution of Bipedalism and Assisted Birth". Medical Anthropology Quarterly 10, n. 2 (giugno 1996): 287–90. http://dx.doi.org/10.1525/maq.1996.10.2.02a00100.

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Miller, Shannon M., Tina Wang e David R. Liu. "Phage-assisted continuous and non-continuous evolution". Nature Protocols 15, n. 12 (16 novembre 2020): 4101–27. http://dx.doi.org/10.1038/s41596-020-00410-3.

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Tesi sul tema "Assisted evolution"

Woolley, Brian G. "Novelty-Assisted Interactive Evolution of Control Behaviors". Doctoral diss., University of Central Florida, 2012. http://digital.library.ucf.edu/cdm/ref/collection/ETD/id/5579.

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The field of evolutionary computation is inspired by the achievements of natural evolution, in which there is no final objective. Yet the pursuit of objectives is ubiquitous in simulated evolution because evolutionary algorithms that can consistently achieve established benchmarks are lauded as successful, thus reinforcing this paradigm. A significant problem is that such objective approaches assume that intermediate stepping stones will increasingly resemble the final objective when in fact they often do not. The consequence is that while solutions may exist, searching for such objectives may not discover them. This problem with objectives is demonstrated through an experiment in this dissertation that compares how images discovered serendipitously during interactive evolution in an online system called Picbreeder cannot be rediscovered when they become the final objective of the very same algorithm that originally evolved them. This negative result demonstrates that pursuing an objective limits evolution by selecting offspring only based on the final objective. Furthermore, even when high fitness is achieved, the experimental results suggest that the resulting solutions are typically brittle, piecewise representations that only perform well by exploiting idiosyncratic features in the target. In response to this problem, the dissertation next highlights the importance of leveraging human insight during search as an alternative to articulating explicit objectives. In particular, a new approach called novelty-assisted interactive evolutionary computation (NA-IEC) combines human intuition with a method called novelty search for the first time to facilitate the serendipitous discovery of agent behaviors. In this approach, the human user directs evolution by selecting what is interesting from the on-screen population of behaviors. However, unlike in typical IEC, the user can then request that the next generation be filled with novel descendants, as opposed to only the direct descendants of typical IEC. The result of such an approach, unconstrained by a priori objectives, is that it traverses key stepping stones that ultimately accumulate meaningful domain knowledge. To establishes this new evolutionary approach based on the serendipitous discovery of key stepping stones during evolution, this dissertation consists of four key contributions: (1) The first contribution establishes the deleterious effects of a priori objectives on evolution. The second (2) introduces the NA-IEC approach as an alternative to traditional objective-based approaches. The third (3) is a proof-of-concept that demonstrates how combining human insight with novelty search finds solutions significantly faster and at lower genomic complexities than fully-automated processes, including pure novelty search, suggesting an important role for human users in the search for solutions. Finally, (4) the NA-IEC approach is applied in a challenge domain wherein leveraging human intuition and domain knowledge accelerates the evolution of solutions for the nontrivial octopus-arm control task. The culmination of these contributions demonstrates the importance of incorporating human insights into simulated evolution as a means to discovering better solutions more rapidly than traditional approaches.
ID: 031001574; System requirements: World Wide Web browser and PDF reader.; Mode of access: World Wide Web.; Adviser: Kenneth O. Stanley.; Title from PDF title page (viewed August 26, 2013).; Thesis (Ph.D.)--University of Central Florida, 2012.; Includes bibliographical references (p. 129-138).
Ph.D.
Doctorate
Electrical Engineering and Computing
Engineering and Computer Science
Computer Engineering

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Marshall, Andrew D. "Template-assisted program restructuring with application to communications infrastructure evolution". Thesis, National Library of Canada = Bibliothèque nationale du Canada, 2000. http://www.collectionscanada.ca/obj/s4/f2/dsk1/tape3/PQDD_0016/NQ58151.pdf.

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Martin, Marti Sergio. "Robotically assisted evolution of gold nanoparticles and their hybridation with POMs". Thesis, University of Glasgow, 2017. http://theses.gla.ac.uk/8631/.

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The work presented in this thesis focused on the synthesis of gold nanoparticles, exploring new ways to synthesise them and also using new tools to improve the study and discovery of new nanomaterials. Whilst there has been a special concern in understanding how they are organised and which are the best conditions to achieve specific shapes, there is gap in finding new approaches that can allow fast synthesis of nanoparticles and fast screening of the chemical space and real time observation of the reaction under different reaction conditions. In the first chapter of this thesis we are going to present a new synthesis method to prepare gold nanoparticles-POM hybrids. Also, we will discuss how POMs can influence the aggregation of nanoparticles, depending on the size and charge of the POM. For example, gold nanoparticles will aggregate more easily if they are surrounded by small and less negatively charged POMs. In the next chapters of the thesis, we will aim to demonstrate that an automated system is able to evolve gold nanomaterials, this means that an automated system will use raw materials (simple chemicals, in this specific case HAuCl4, CTAB and NaBH4) to synthesise very simple nanostructures, such as spheres, then reuse those spheres and other chemicals to produce even more complex structures. In chapter 2 we will go through the process of building an automated system, in this case, the system will be designed to synthesise gold nanoparticles. We will start by designing the automated system and testing it, we will see the flaws that those different systems had and how we overcame them by doing some improvements on them, such as more control over the temperature of the reaction, keeping a constant temperature of the reagents, improving the cleaning process, trying different concentrations of the reagents, trying different algorithms and different ways to calculate the fitness factor, etc. until we found a system that was very reliable, which was able to provide reproducible results. In the last chapter of this thesis, we will focus on the results obtained in the different versions of the automated system. First, we will explain our first objective, which was obtaining gold nanorods of very short aspect ratio. We will analyse the results we obtained for that objective, trying different fitness factor calculations and how the different ways to calculate the fitness factor affected the process to obtain the desired product. We will discuss why we changed the fitness factor calculation and how this helped to achieve our objective. Then, we will jump to the next level of the project, which was to synthesise very simple gold nanoparticles from raw chemicals and reuse these simple structures to obtain more complex structures. This demonstrates that we have an automated system able to evolve gold nanomaterials; the first of this kind. In this chapter, we will also talk about the different techniques used to characterise the product, where we used in-line analytical techniques such as UV-Vis or image analysis (which are the ones used to calculate the fitness factor that the algorithm is going to use) and other techniques to fully characterise the final product such as TEM.

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Huang, Changwu. "Kriging-assisted evolution strategy for optimization and application in material parameters identification". Thesis, Normandie, 2017. http://www.theses.fr/2017NORMIR05.

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Afin de réduire le coût de calcul pour des problèmes d'optimisation coûteuse, cette thèse a été consacrée à la Stratégie d'Evolution avec Adaptation de Matrice de Covariance assistée par modèle de Krigeage (KA-CMA-ES). Plusieurs algorithmes de KA-CMA-ES ont été développés et étudiés. Une application de ces algorithmes KA-CMA-ES développés est réalisée par l'identification des paramètres matériels avec un modèle constitutif d'endommagement élastoplastique. Les résultats expérimentaux démontrent que les algorithmes KA-CMA-ES développés sont plus efficaces que le CMA-ES standard. Ils justifient autant que le KA-CMA-ES couplé avec ARP-EI est le plus performant par rapport aux autres algorithmes étudiés dans ce travail. Les résultats obtenus par l'algorithme ARP-EI dans l'identification des paramètres matériels montrent que le modèle d'endommagement élastoplastique utilisé est suffisant pour décrire le comportement d'endommage plastique et ductile. Ils prouvent également que la KA-CMA-ES proposée améliore l'efficace de la CMA-ES. Par conséquent, le KA-CMA-ES est plus puissant et efficace que CMA-ES pour des problèmes d'optimisation coûteuse
In order to reduce the cost of solving expensive optimization problems, this thesis devoted to Kriging-Assisted Covariance Matrix Adaptation Evolution Strategy (KA-CMA-ES). Several algorithms of KA-CMA-ES were developed and a comprehensive investigation on KA-CMA-ES was performed. Then applications of the developed KA-CMA-ES algorithm were carried out in material parameter identification of an elastic-plastic damage constitutive model. The results of experimental studies demonstrated that the developed KA-CMA-ES algorithms generally are more efficient than the standard CMA-ES and that the KA-CMA-ES using ARP-EI has the best performance among all the investigated KA-CMA-ES algorithms in this work. The results of engineering applications of the algorithm ARP-EI in material parameter identification show that the presented elastic-plastic damage model is adequate to describe the plastic and ductile damage behavior and also prove that the proposed KA-CMA-ES algorithm apparently improve the efficiency of the standard CMA-ES. Therefore, the KA-CMA-ES is more powerful and efficient than CMA-ES for expensive optimization problems

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Badran, Ahmed. "Advances in Phage-Assisted Continuous Evolution and Application to Overcoming Bioinsecticide Resistance". Thesis, Harvard University, 2016. http://nrs.harvard.edu/urn-3:HUL.InstRepos:33493579.

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The Bacillus thuringiensis δ-endotoxins (Bt toxins) are widely used insecticidal proteins in engineered crops that provide agricultural, economic, and environmental benefits, constituting a substantial and increasingly large portion of the total global production of various crops, including cotton, corn, maize and soybeans. Bt toxins are exquisitely selective for targeted pests, typically do not affect off-target insects, and are completely orthogonal to human biology. However, the development of insect resistance to Bt toxins endangers their long-term effectiveness. In this thesis, I describe the development of methodology for the systematic directed evolution of novel Bt toxins to selectively affect resistant insects. Using Phage-Assisted Continuous Evolution (PACE), a previously developed general platform for the continuous directed evolution of biomolecules, I developed a highly sensitized selection for novel protein-protein interactions. This system robustly reported on interactions spanning affinities from low micromolar to picomolar. However, attempts at using this system for the directed evolution of novel protein-protein interactions were largely unsuccessful, presumably as a consequence of low mutagenesis efficiency. To increase the utility of the platform, I sought to enhance the mutagenesis levels afforded by PACE, but current in vivo methods suffer from a lack of control, genomic instability, low efficiency, and narrow mutational spectra. I used a systematic, mechanism-driven approach to create a potent, inducible, broad-spectrum, and vector-based mutagenesis system in E. coli that enhances mutation rates by 322,000-fold over basal levels, surpassing the mutational efficiency and spectra of widely used in vivo and in vitro mutagenesis methods. This system enabled the high-frequency, broad-spectrum mutagenesis of chromosomal, episomal, and viral nucleic acids in vivo, and dramatically enhanced the success of PACE experiments, highlighting the importance of mutagenesis efficiency on selection outcome. Using this enhanced mutagenesis approach and the previously described sensitized selection platform, I was able to evolve variants of the commonly used Bt toxin Cry1Ac that bind toxin binding region of a cadherin-like receptor from the insect pest Trichoplusia ni (TnCAD) that is not targeted by wild-type Cry1Ac. The resulting evolved Cry1Ac variants bind TnCAD with high affinity (Kd = 11-41 nM), kill TnCAD-expressing insect cells that are not susceptible to wild-type Cry1Ac, and kill Cry1Ac-resistant T. ni insects up to 335-fold more potently than wild-type Cry1Ac. Our findings establish that the evolution of Bt toxins with novel insect cell receptor affinity can overcome Bt toxin resistance in insects and confer lethality approaching that of the wild-type Bt toxin against non-resistant insects. In conclusion, these finding offer a novel mechanism of overcoming what is quickly becoming among the largest issue overshadowing the continued success of Bt toxins for pest control and management, and establish a platform for the detection and evolution of a wide array of protein-protein interactions.
Chemical Biology

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Horsman, Geoffrey Paul. "Directed evolution and structure-assisted random mutagenesis to enhance enantioselectivity of an esterase from Pseudomonas fluorescens". Thesis, McGill University, 2001. http://digitool.Library.McGill.CA:80/R/?func=dbin-jump-full&object_id=33759.

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By screening a low number of Pseudomonas fluorescens (PFE) mutants, directed evolution identified a mutant with modestly improved enantioselectivity (from Ewild-type = 12 to EThr230Ile = 19) toward the useful chiral synthon methyl 3-bromo-2-methylpropionate (MBMP). A homology model of HE revealed that the mutation was far away from the enzyme active site and may contribute to increased enzyme flexibility.
In a second approach to improving enantioselectivity of PFE toward MBMP, the homology model was used to select amino acid residues near the stereocenter of the docked tetrahedral intermediate of the substrate. Randomization of these residues yielded a Trp29Leu mutant with E increased to 58, as well as a Phe199Trp mutant with E decreased to 2.

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Petrescue, Laura. "An investigation of defect evolution in foam core sandwich structures produced using vacuum assisted resin transfer moulding". Thesis, University of Ottawa (Canada), 2007. http://hdl.handle.net/10393/27904.

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In this work, a resin infusion process used by Flight Dynamics Corp. was investigated for the fabrication of low-cost composite sandwich structures. Trials were performed to establish a complete set of potential defects that could develop during the manufacture of E-glass epoxy vinyl ester sandwich panels. A series of non-destructive evaluation techniques were examined for their potential to identify two representative defects. It was found that thermography and bondline analysis were effective at detecting defects such as dry spots and incomplete resin infiltration. However, due to technical limitations of these methods visual inspection of high quality digital images proved to be the most accurate method for evaluating the specimens. The effect of these defects was also evaluated through a selection of compression tests. These tests showed that the sensitivity of this test to the presence of defects is low. A parametric study of the infusion process was performed to evaluate the potential of defect evolution under controlled conditions. The evolution of defects was most affected by the vacuum pressure level and the method for distributing resin through the thickness of the sandwich panel. As part of this study, the resin flow front was evaluated to determine the effect on the evolution of defects. A series of defect metrics were developed for a variety of resin distribution methods. In general, it was found that defect evolution due to a single variable was limited and that further evaluation of the interaction of process parameters would be useful to optimize the process.

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Mutti, Jasdeep Singh. "Targeted improvement of the wheat genome by marker-assisted selection and understanding its homoeologous gene evolution and expression balance". Online access for everyone, 2007. http://www.dissertations.wsu.edu/Dissertations/Fall2007/j_mutti_123007.pdf.

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Thompson, David Brandon. "Development of Methods for Protein Delivery and the Directed Evolution of Recombinases". Thesis, Harvard University, 2014. http://nrs.harvard.edu/urn-3:HUL.InstRepos:13097816.

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As a class, protein-based therapeutics offer tremendous advantages over traditional small molecule drugs. Due to their sizes and folding energies, proteins are ideal for catalyzing chemical reactions, and can bind tightly and selectively to extended target surfaces. However, due to their large size, virtually all proteins are unable to spontaneously enter cells, and as a result protein therapeutics are restricted to extracellular targets. We developed a platform for delivery of proteins to intracellular target sites by engineering the surface chemistry of a model protein, green fluorescent protein (GFP). We found that 'supercharged' cationic GFP variants (scGFPs) bind to anionic cell surface molecules and initiate endocytosis, resulting in the efficient delivery of translationally fused cargo to intracellular targets. We discovered that scGFPs, and cationic delivery reagents in general, alter endosomal trafficking in a manner proportional to both their charge and their delivery efficiency, suggesting that avoidance of endosomal maturation is a key step in the endosomal escape of delivered protein cargos. We also developed a method for encapsulation of recombinant proteins by cationic lipid delivery reagents using negatively supercharged GFP. Genetic modification technologies have matured rapidly following the discovery of protein classes with programmable DNA-binding specificities. While site-directed genetic knockout technologies are highly effective, targeted integration and repair remain comparatively inefficient. Site-specific recombinases directly catalyze strand exchange and ligation between DNA molecules, offering an approach to efficient genomic integration. However, most site-specific recombinases are not easily reprogrammable. To address this problem, we developed a genetic selection technique based on the Phage-Assisted Continuous Evolution (PACE) system, to enable the rapid evolution of recombinase proteins towards targets of interest. Using Cre recombinase as a model, the PACE system was optimized, validated, and used to evolve Cre variants with higher activity on their native loxP target site, as well as altered specificity towards a human genomic sequence within the hROSA26 locus. Finally, we developed a method for enhancing the specificity of RNA-guided nucleases by restricting activity to sites of obligate dimeric nuclease assembly. We engineered a FokI nuclease fusion to a catalytically inactivated Cas9 protein that mediates efficient modification with significantly reduced off-target activity.

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Tarek, Md Tawhid Bin. "Optimal High-Speed Design and Rotor Shape Modification of Multiphase Permanent Magnet Assisted Synchronous Reluctance Machines for Stress Reduction". University of Akron / OhioLINK, 2017. http://rave.ohiolink.edu/etdc/view?acc_num=akron1510617496931844.

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Libri sul tema "Assisted evolution"

Jain, L. C., Debra K. Tedman e Raymond A. Tedman. Evolution of teaching and learning paradigms in intelligent environment. Berlin: Springer, 2010.

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Levinson, Paul. Learning cyberspace: Essays on the evolution of media and the new education. San Francisco: Anamnesis Press, 1995.

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Koul, B. N. Higher distance/virtual education in the Anglophone Caribbean: A report on the evolution, present status, and future prospects of higher virtual education in theAnglophone [sic] Caribbean. Caracas: International Institute for Higher Education in Latin America and the Caribbean, 2005.

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1910-, Jones Howard Wilbur, a cura di. "Legally speaking": The evolution and challenges of reproductive technology law. Baltimore: Johns Hopkins University Press, 2009.

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1973-, Lytras Miltiadis D., e Sheth A. 1959-, a cura di. Progressive concepts for Semantic Web evolution: Applications and developments. Hershey PA: Information Science Reference, 2010.

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International Conference on Informatics in Schools: Situation, Evolution and Perspectives (5th 2011 Bratislava, Slovakia). Informatics in schools : contributing to 21st century education: 5th International Conference on Informatics in Schools: Situation, Evolution and Perspectives, ISSEP 2011, Bratislava, Slovakia, October 26 - 29, 2011 : proceedings. A cura di Kalaš Ivan e Mittermeir Roland. Heidelberg: Springer, 2011.

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Seminaire International de Traduction Assistee par Ordinateur (1988 Paris). La traduction assistee par ordinateur: Perspectives technologiques, industrielles et economiques envisageables a l'horizon 1990 : l'offre, la demande, les marches et les evolutions en cours : actes du seminaire international (Paris, 17-18 mars 1988) et dossiers complementaires. Paris: DAICADIF, 1989.

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Flores, Damon. E-Learning: Evolution, Strategies and Technologies. Nova Science Publishers, Incorporated, 2016.

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(Editor), Catherine Schifter, Linda Greenwood (Editor) e Dominique Monolescu (Editor), a cura di. The Distance Education Evolution: Issues and Case Studies. Information Science Publishing, 2003.

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Tedman, Debra K., e Raymond A. Tedman. Evolution of Teaching and Learning Paradigms in Intelligent Environment. Springer London, Limited, 2011.

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Capitoli di libri sul tema "Assisted evolution"

Ulmer, Holger, Felix Streichert e Andreas Zell. "Model Assisted Evolution Strategies". In Knowledge Incorporation in Evolutionary Computation, 333–55. Berlin, Heidelberg: Springer Berlin Heidelberg, 2005. http://dx.doi.org/10.1007/978-3-540-44511-1_16.

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Emmerich, Michael, Alexios Giotis, Mutlu Özdemir, Thomas Bäck e Kyriakos Giannakoglou. "Metamodel—Assisted Evolution Strategies". In Parallel Problem Solving from Nature — PPSN VII, 361–70. Berlin, Heidelberg: Springer Berlin Heidelberg, 2002. http://dx.doi.org/10.1007/3-540-45712-7_35.

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Petrini, O., e T. N. Sieber. "Computer-Assisted Taxonomy and Documentation". In Systematics and Evolution, 203–16. Berlin, Heidelberg: Springer Berlin Heidelberg, 2001. http://dx.doi.org/10.1007/978-3-662-10189-6_8.

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Bai, Wei, Yuan Gao e Ronglei Sun. "Microstructural Evolution in Vibration Assisted Cutting". In Vibration Assisted Machining, 135–53. Singapore: Springer Nature Singapore, 2023. http://dx.doi.org/10.1007/978-981-19-9131-8_8.

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Unger, F. "Counterpulsation: Stagnation or Evolution in Assisted Circulation?" In Assisted Circulation 3, 49–51. Berlin, Heidelberg: Springer Berlin Heidelberg, 1989. http://dx.doi.org/10.1007/978-3-642-74404-4_4.

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Sahu, Rupsa Rani, Anjana Raut e Swati Samantaray. "Technology-Assisted Mental Healthcare: A Novel Approach". In Evolution in Computational Intelligence, 565–75. Singapore: Springer Nature Singapore, 2023. http://dx.doi.org/10.1007/978-981-19-7513-4_49.

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Ghaisas, S., e N. Ajmeri. "Knowledge-Assisted Ontology-Based Requirements Evolution". In Managing Requirements Knowledge, 143–67. Berlin, Heidelberg: Springer Berlin Heidelberg, 2013. http://dx.doi.org/10.1007/978-3-642-34419-0_7.

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Ulmer, Holger, Felix Streichert e Andreas Zell. "Model-Assisted Steady-State Evolution Strategies". In Genetic and Evolutionary Computation — GECCO 2003, 610–21. Berlin, Heidelberg: Springer Berlin Heidelberg, 2003. http://dx.doi.org/10.1007/3-540-45105-6_72.

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Christou, George, Giorgos Vasiliadis, Elias Athanasopoulos e Sotirios Ioannidis. "The Evolution of Hardware-Assisted Security". In Cybersecurity Issues in Emerging Technologies, 1–20. Boca Raton: CRC Press, 2021. http://dx.doi.org/10.1201/9781003109952-1.

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Packer, Mark, Richard L. Lindstrom e Elizabeth A. Davis. "Evolution of Cataract Surgery". In Textbook of Refractive Laser Assisted Cataract Surgery (ReLACS), 1–8. New York, NY: Springer New York, 2012. http://dx.doi.org/10.1007/978-1-4614-1010-2_1.

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Atti di convegni sul tema "Assisted evolution"

Yang, Xiaoying, Yujing Gu, Fuhua Jia, Yiran Li, Hongru Wang, Nanjiang Du, Tianxiang Cui, Yujian Ye e Ruibin Bai. "Evolution-Assisted Deep Reinforcement Learning for Fast Charging Station Coordinated Operation". In 2024 IEEE Congress on Evolutionary Computation (CEC), 1–9. IEEE, 2024. http://dx.doi.org/10.1109/cec60901.2024.10611768.

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Mazhukin, Vladimir I., Vadim V. Nossov e Igor Smurov. "Breakdown kinetics and plasma evolution induced by IR and UV laser radiation". In Laser-Assisted Microtechnology 2000, a cura di Vadim P. Veiko. SPIE, 2001. http://dx.doi.org/10.1117/12.413772.

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Chudy, Peter, Jan Vlk e Petr Dittrich. "Evolution assisted flight control system design". In 2013 IEEE/AIAA 32nd Digital Avionics Systems Conference (DASC). IEEE, 2013. http://dx.doi.org/10.1109/dasc.2013.6712641.

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Kumar, Manish, Nirav Ajmeri e Smita Ghaisas. "Towards knowledge assisted agile requirements evolution". In the 2nd International Workshop. New York, New York, USA: ACM Press, 2010. http://dx.doi.org/10.1145/1808920.1808924.

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Mallipeddi, Rammohan, e Minho Lee. "Surrogate model assisted ensemble differential evolution algorithm". In 2012 IEEE Congress on Evolutionary Computation (CEC). IEEE, 2012. http://dx.doi.org/10.1109/cec.2012.6256479.

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"Computer-assisted analysis of caspases molecular evolution". In Bioinformatics of Genome Regulation and Structure/ Systems Biology. institute of cytology and genetics siberian branch of the russian academy of science, Novosibirsk State University, 2020. http://dx.doi.org/10.18699/bgrs/sb-2020-095.

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Jin, Chen, A. K. Qin e Ke Tang. "Local ensemble surrogate assisted crowding differential evolution". In 2015 IEEE Congress on Evolutionary Computation (CEC). IEEE, 2015. http://dx.doi.org/10.1109/cec.2015.7256922.

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Lu, Xiaofen, Ke Tang e Xin Yao. "Classification-assisted Differential Evolution for computationally expensive problems". In 2011 IEEE Congress on Evolutionary Computation (CEC). IEEE, 2011. http://dx.doi.org/10.1109/cec.2011.5949859.

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Rapporti di organizzazioni sul tema "Assisted evolution"

Bay, Line, Juan Ortiz, Adriana Humanes, Cynthia Riginos, Iliana Baums, Hugo Scharfenstein, Manuel Aranda et al. CORDAP R&D Technology Roadmap for Understanding Natural Adaptation and Assisted Evolution of Corals to Climate Change. CORDAP, settembre 2023. http://dx.doi.org/10.62542/gq8m3cy5.

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Cataneda, H., B. N. Leis Leis e S. E. Rose. DTRS56-05-T-0003 Report on Model Modules to Assist Assessing and Controlling SCC. Chantilly, Virginia: Pipeline Research Council International, Inc. (PRCI), aprile 2008. http://dx.doi.org/10.55274/r0011757.

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PHMSA report. This project developed and validated tools to assist in integrity assessment and management in both forms of SCC. Because the understanding that underlies integrity management tools was most comprehensive for high-pH SCC, development targeted NN-pH SCC, with work on high pH SCC being more application-oriented. To broaden the utility of the deliverables, this project targeted technology in the context of generic modules applicable to both forms of cracking, recognizing their key difference lies in the mechanisms of cracking and how that impacts their kinetics and pipeline susceptibility. For the high-pH scenario, the work was focused on tools to facilitate the evaluation of factors that drive day to day integrity-management decisions. In contrast, work for NN-pH situations targeted was at the level of understanding the mechanisms that underlie the evolution of hydrogen involved with this form of SCC. Some key conclusions include: a mechanism for NN-pH SCC was developed and modeled in a fundamental framework, and found to produce hydrogen in sufficient quantity to support crack nucleation and growth under typical pipeline service conditions; a spectrum of reversible environments exist that sandwich NN-pH SCC between corrosion at lower pH levels and high-pH SCC that bounds the high end, each of corrosion, high-pH SCC, and NN-pH SCC is possible either individually or in association with the same crack; conditions driving NN-pH SCC were found to be consistent with temperature conditions throughout the United States. A host of other conclusions and recommendations also were developed.

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Roye, Thorsten. Unsettled Technology Areas in Deterministic Assembly Approaches for Industry 4.0. SAE International, agosto 2021. http://dx.doi.org/10.4271/epr2021018.

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Increased production rates and cost reduction are affecting manufacturing in all sectors of the mobility industry. One enabling methodology that could achieve these goals in the burgeoning “Industry 4.0” environment is the deterministic assembly (DA) approach. The DA approach is defined as an optimized assembly process; it always forms the same final structure and has a strong link to design-for-assembly and design-for-automation methodologies. It also looks at the whole supply chain, enabling drastic savings at the original equipment manufacturer (OEM) level by reducing recurring costs and lead time. Within Industry 4.0, DA will be required mainly for the aerospace and the space industry, but serves as an interesting approach for other industries assembling large and/or complex components. In its entirety, the DA approach connects an entire supply chain—from part manufacturing at an elementary level to an OEM’s final assembly line level. Addressing the whole process of aircraft design and manufacturing is necessary to develop further collaboration models between OEMs and the supply chain, including addressing the most pressing technology challenges. Since all parts aggregate at the OEM level, the OEM—as an integrator of all these single parts—needs special end-to-end methodologies to drastically decrease cost and lead time. This holistic approach can be considered in part design as well (in the design-for-automation and design-for-assembly philosophy). This allows for quicker assembly at the OEM level, such as “part-to-part” or “hole-to-hole” approaches, versus traditional, classical assembly methods like manual measurement or measurement-assisted assembly. In addition, it can increase flexibility regarding rate changes in production (such as those due to pandemic- or climate-related environmental challenges). The standardization and harmonization of these areas would help all industries and designers to have a deterministic approach with an end-to-end concept. Simulations can easily compare possible production and assembly steps with different impacts on local and global tolerances. Global measurement feedback needs high-accuracy turnkey solutions, which are very costly and inflexible. The goal of standardization would be to use Industry 4.0 feedback and features, as well as to define several building blocks of the DA approach as a one-way assembly (also known as one-up assembly, or “OUA”), false one-way assembly, “Jig-as-Master,” etc., up to the hole-to-hole assembly approach. The evolution of these assembly principles and the link to simulation approaches are undefined and unsolved domains; they are discussed in this report. They must be discussed in greater depth with aims of (first) clarifying the scope of the industry-wide alignment needs and (second) prioritizing the issues requiring standardization. NOTE: SAE EDGE™ Research Reports are intended to identify and illuminate key issues in emerging, but still unsettled, technologies of interest to the mobility industry. The goal of SAE EDGE™ Research Reports is to stimulate discussion and work in the hope of promoting and speeding resolution of identified issues. SAE EDGE™ Research Reports are not intended to resolve the challenges they identify or close any topic to further scrutiny.

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Fahima, Tzion, e Jorge Dubcovsky. Map-based cloning of the novel stripe rust resistance gene YrG303 and its use to engineer 1B chromosome with multiple beneficial traits. United States Department of Agriculture, gennaio 2013. http://dx.doi.org/10.32747/2013.7598147.bard.

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Research problem: Bread wheat (Triticumaestivum) provides approximately 20% of the calories and proteins consumed by humankind. As the world population continues to increase, it is necessary to improve wheat yields, increase grain quality, and minimize the losses produced by biotic and abiotic stresses. Stripe rust, caused by Pucciniastriiformisf. sp. tritici(Pst), is one of the most destructive diseases of wheat. The new pathogen races are more virulent and aggressive than previous ones and have produced large economic losses. A rich source for stripe-rust resistance genes (Yr) was found in wild emmer wheat populations from Israel. Original Project goals: Our long term goal is to identify, map, clone, characterize and deploy in breeding, novel wild emmer Yr genes, and combine them with multiple beneficial traits. The current study was aiming to map and clone YrG303 and Yr15, located on chromosome 1BS and combine them with drought resistance and grain quality genes. Positional cloning of YrG303/Yr15: Fine mapping of these genes revealed that YrG303 is actually allelic to Yr15. Fine genetic mapping using large segregating populations resulted in reduction of the genetic interval spanning Yr15 to less than 0.1 cM. Physical mapping of the YrG303/Yr15 locus was based on the complete chromosome 1BS physical map of wheat constructed by our group. Screening of 1BS BAC library with Yr15 markers revealed a long BAC scaffold covering the target region. The screening of T. dicoccoidesaccession-specific BAC library with Yr15 markers resulted in direct landing on the target site. Sequencing of T. dicoccoidesBAC clones that cover the YrG303/Yr15 locus revealed a single candidate gene (CG) with conserved domains that may indicate a role in disease resistance response. Validation of the CG was carried out using EMS mutagenesis (loss-of- function approach). Sequencing of the CG in susceptible yr15/yrG303 plants revealed three independent mutants that harbour non-functional yr15/yrG303 alleles within the CG conserved domains, and therefore validated its function as a Pstresistance gene. Evaluation of marker-assisted-selection (MAS) for Yr15. Introgressions of Yr15 into cultivated wheat are widely used now. Recently, we have shown that DNA markers linked to Yr15 can be used as efficient tools for introgression of Yr15 into cultivated wheat via MAS. The developed markers were consistent and polymorphic in all 34 tested introgressions and are the most recommended markers for the introgression of Yr15. These markers will facilitate simultaneous selection for multiple Yr genes and help to avoid escapees during the selection process. Engineering of improved chromosome 1BS that harbors multiple beneficial traits. We have implemented the knowledge and genetic resources accumulated in this project for the engineering of 1B "super-chromosome" that harbors multiple beneficial traits. We completed the generation of a chromosome including the rye 1RS distal segment associated with improved drought tolerance with the Yr gene, Yr15, and the strong gluten allele 7Bx-over-expressor (7Bxᴼᴱ). We have completed the introgression of this improved chromosome into our recently released variety Patwin-515HP and our rain fed variety Kern, as well as to our top breeding lines UC1767 and UC1745. Elucidating the mechanism of resistance exhibited by Yr36 (WKS1). The WHEAT KINASE START1 (WKS1) resistance gene (Yr36) confers partial resistance to Pst. We have shown that wheat plants transformed with WKS1 transcript are resistant to Pst. WKS1 is targeted to the chloroplast where it phosphorylates the thylakoid-associatedascorbateperoxidase (tAPX) and reduces its ability to detoxify peroxides. Based on these results, we propose that the phosphorylation of tAPX by WKS1 reduces the ability of the cells to detoxify ROS and contributes to cell death. Distribution and diversity of WKS in wild emmer populations. We have shown that WKS1 is present only in the southern distribution range of wild emmer in the Fertile Crescent. Sequence analysis revealed a high level of WKS1 conservation among wild emmer populations, in contrast to the high level of diversity observed in NB-LRR genes. This phenomenon shed some light on the evolution of genes that confer partial resistance to Pst. Three new WKS1 haplotypes displayed a resistance response, suggesting that they can be useful to improve wheat resistance to Pst. In summary, we have improved our understanding of cereals’ resistance mechanisms to rusts and we have used that knowledge to develop improved wheat varieties.

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Wolfe, S. A., H. B. O'Neill, C. Duchesne, D. Froese, J M Young e S. V. Kokelj. Ground ice degradation and thermokarst terrain formation in Canada over the past 16 000 years. Natural Resources Canada/CMSS/Information Management, 2022. http://dx.doi.org/10.4095/329668.

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Thermokarst results from thawing of excess ground ice in permafrost sediments. Thermokarst processes and landforms are controlled by ground ice type, amount and distribution, as well as the patterns of ground ice loss over time. Recent acceleration of varied thermokarst processes across diverse Canadian permafrost terrains make for a challenging task in predicting landscape-scale thaw trajectories. Using existing ground ice models, we examined the modelled amounts and spatial extent of ground ice loss relative to ground ice maxima in the last ca. 16 ka BP for relict, segregated and wedge ice. We relate observed thermokarst features to the nature of ground ice development and loss in different environments (cold continuous permafrost, discontinuous permafrost, and no current permafrost). In cold, continuous permafrost areas where ground ice loss has been limited over the last 16 ka BP, thermokarst processes include active layer detachments and slumps in segregated and relict ice, gullying and ponding in ice wedge troughs, and the cyclical development of shallow thermokarst ponds in segregated ice. With ground ice loss in discontinuous permafrost, thermokarst processes are wide-ranging. Slumps, subsidence, and collapse of lithalsas, palsas and peat plateaus occur from thawing of segregated ice, thermokarst ponds from melting wedge and segregated ice, and involuted terrain from melting and creep of relict or segregated ice. In former permafrost terrain, evidence of thermokarst includes former ice wedge polygons, collapsed lithalsas, and irregular hummocky terrain. The relations between modelled ground ice loss and observed thermokarst landscapes assist in understanding present-day processes and in predicting future thermokarst landform evolution with a changing climate.

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Kiianovska, N. M. The development of theory and methods of using cloud-based information and communication technologies in teaching mathematics of engineering students in the United States. Видавничий центр ДВНЗ «Криворізький національний університет», dicembre 2014. http://dx.doi.org/10.31812/0564/1094.

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The purpose of the study is the analysis of the development of the theory and methods of ICT usage while teaching higher mathematics engineering students in the United States. It was determined following tasks: to analyze the problem source, to identify the state of its elaboration, to identify key trends in the development of theory and methods of ICT usage while teaching higher mathematics engineering students in the United States, the object of study – the use of ICT in teaching engineering students, the research methods are: analysis of scientific, educational, technical, historical sources; systematization and classification of scientific statements on the study; specification, comparison, analysis and synthesis, historical and pedagogical analysis of the sources to establish the chronological limits and implementation of ICT usage in educational practice of U.S. technical colleges. In article was reviewed a modern ICT tools used in learning of fundamental subjects for future engineers in the United States, shown the evolution and convergence of ICT learning tools. Discussed experience of the «best practices» using online ICT in higher engineering education at United States. Some of these are static, while others are interactive or dynamic, giving mathematics learners opportunities to develop visualization skills, explore mathematical concepts, and obtain solutions to self-selected problems. Among ICT tools are the following: tools to transmit audio and video data, tools to collaborate on projects, tools to support object-oriented practice. The analysis leads to the following conclusion: using cloud-based tools of learning mathematic has become the leading trend today. Therefore, university professors are widely considered to implement tools to assist the process of learning mathematics such properties as mobility, continuity and adaptability.

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Hulata, Gideon, Thomas D. Kocher, Micha Ron e Eyal Seroussi. Molecular Mechanisms of Sex Determination in Cultured Tilapias. United States Department of Agriculture, ottobre 2010. http://dx.doi.org/10.32747/2010.7697106.bard.

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Tilapias are among the most important aquaculture commodities worldwide. Commercial production of tilapia is based on monosex culture of males. Current methods for producing all-male fingerlings, including hormone treatments and genetic manipulations, are not entirely reliable, in part because of the genetic complexity of sex determination and sexual differentiation in tilapias. The goals of this project are to map QTL and identify genes regulating sex determination in commonly cultured tilapia species, in order to provide a rational basis for designing reliable genetic approaches for producing all-male fingerlings. The original objectives for this research were: 1) to identify the gene underlying the QTL on LG1 through positional cloning and gene expression analysis; 2) to fine map the QTL on LG 3 and 23; and 3) to characterize the patterns of dominance and epistasis among QTL alleles influencing sex determination. The brain aromatase gene Cyp19b, a possible candidate for the genetic or environmental SD, was mapped to LG7 using our F2 mapping population. This region has not been identified before as affecting SD in tilapias. The QTL affecting SD on LG 1 and 23 have been fine-mapped down to 1 and 4 cM, respectively, but the key regulators for SD have not been found yet. Nevertheless, a very strong association with gender was found on LG23 for marker UNH898. Allele 276 was found almost exclusively in males, and we hypothesized that this allele is a male-associated allele (MAA). Mating of males homozygous for MAA with normal females is underway for production of all-male populations. The first progeny reaching size allowing accurate sexing had 43 males and no females. During the course of the project it became apparent that in order to achieve those objectives there is a need to develop genomic infrastructures that were lacking. Efforts have been devoted to the development of genomic resources: a database consisting of nearly 117k ESTs representing 16 tissues from tilapia were obtained; a web tool based on the RepeatMasker software was designed to assist tilapia genomics; collaboration has been established with a sequencing company to sequence the tilapia genome; steps have been taken toward constructing a microarray to enable comparative analysis of the entire transcriptome that is required in order to detect genes that are differentially expressed between genders in early developmental stages. Genomic resources developed will be invaluable for studies of cichlid physiology, evolution and development, and will hopefully lead to identification of the key regulators of SD. Thus, they will have both scientific and agricultural implications in the coming years.

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Anderson, Donald M., Lorraine C. Backer, Keith Bouma-Gregson, Holly A. Bowers, V. Monica Bricelj, Lesley D’Anglada, Jonathan Deeds et al. Harmful Algal Research & Response: A National Environmental Science Strategy (HARRNESS), 2024-2034. Woods Hole Oceanographic Institution, luglio 2024. http://dx.doi.org/10.1575/1912/69773.

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Harmful and toxic algal blooms (HABs) are a well-established and severe threat to human health, economies, and marine and freshwater ecosystems on all coasts of the United States and its inland waters. HABs can comprise microalgae, cyanobacteria, and macroalgae (seaweeds). Their impacts, intensity, and geographic range have increased over past decades due to both human-induced and natural changes. In this report, HABs refers to both marine algal and freshwater cyanobacterial events. This Harmful Algal Research and Response: A National Environmental Science Strategy (HARRNESS) 2024-2034 plan builds on major accomplishments from past efforts, provides a state of the science update since the previous decadal HARRNESS plan (2005-2015), identifies key information gaps, and presents forward-thinking solutions. Major achievements on many fronts since the last HARRNESS are detailed in this report. They include improved understanding of bloom dynamics of large-scale regional HABs such as those of Pseudo-nitzschia on the west coast, Alexandrium on the east coast, Karenia brevis on the west Florida shelf, and Microcystis in Lake Erie, and advances in HAB sensor technology, allowing deployment on fixed and mobile platforms for long-term, continuous, remote HAB cell and toxin observations. New HABs and impacts have emerged. Freshwater HABs now occur in many inland waterways and their public health impacts through drinking and recreational water contamination have been characterized and new monitoring efforts have been initiated. Freshwater HAB toxins are finding their way into marine environments and contaminating seafood with unknown consequences. Blooms of Dinophysis spp., which can cause diarrhetic shellfish poisoning, have appeared around the US coast, but the causes are not understood. Similarly, blooms of fish- and shellfish-killing HABs are occurring in many regions and are especially threatening to aquaculture. The science, management, and decision-making necessary to manage the threat of HABs continue to involve a multidisciplinary group of scientists, managers, and agencies at various levels. The initial HARRNESS framework and the resulting National HAB Committee (NHC) have proven effective means to coordinate the academic, management, and stakeholder communities interested in national HAB issues and provide these entities with a collective voice, in part through this updated HARRNESS report. Congress and the Executive Branch have supported most of the advances achieved under HARRNESS (2005-2015) and continue to make HABs a priority. Congress has reauthorized the Harmful Algal Bloom and Hypoxia Research and Control Act (HABHRCA) multiple times and continues to authorize the National Oceanic and Atmospheric Administration (NOAA) to fund and conduct HAB research and response, has given new roles to the US Environmental Protection Agency (EPA), and required an Interagency Working Group on HABHRCA (IWG HABHRCA). These efforts have been instrumental in coordinating HAB responses by federal and state agencies. Initial appropriations for NOAA HAB research and response decreased after 2005, but have increased substantially in the last few years, leading to many advances in HAB management in marine coastal and Great Lakes regions. With no specific funding for HABs, the US EPA has provided funding to states through existing laws, such as the Clean Water Act, Safe Drinking Water Act, and to members of the Great Lakes Interagency Task Force through the Great Lakes Restoration Initiative, to assist states and tribes in addressing issues related to HAB toxins and hypoxia. The US EPA has also worked towards fulfilling its mandate by providing tools and resources to states, territories, and local governments to help manage HABs and cyanotoxins, to effectively communicate the risks of cyanotoxins and to assist public water systems and water managers to manage HABs. These tools and resources include documents to assist with adopting recommended recreational criteria and/or swimming advisories, recommendations for public water systems to choose to apply health advisories for cyanotoxins, risk communication templates, videos and toolkits, monitoring guidance, and drinking water treatment optimization documents. Beginning in 2018, Congress has directed the U.S. Army Corps of Engineers (USACE) to develop a HAB research initiative to deliver scalable HAB prevention, detection, and management technologies intended to reduce the frequency and severity of HAB impacts to our Nation’s freshwater resources. Since the initial HARRNESS report, other federal agencies have become increasingly engaged in addressing HABs, a trend likely to continue given the evolution of regulations(e.g., US EPA drinking water health advisories and recreational water quality criteria for two cyanotoxins), and new understanding of risks associated with freshwater HABs. The NSF/NIEHS Oceans and Human Health Program has contributed substantially to our understanding of HABs. The US Geological Survey, Centers for Disease Control and Prevention, and the National Aeronautics Space Administration also contribute to HAB-related activities. In the preparation of this report, input was sought early on from a wide range of stakeholders, including participants from academia, industry, and government. The aim of this interdisciplinary effort is to provide summary information that will guide future research and management of HABs and inform policy development at the agency and congressional levels. As a result of this information gathering effort, four major HAB focus/programmatic areas were identified: 1) Observing systems, modeling, and forecasting; 2) Detection and ecological impacts, including genetics and bloom ecology; 3) HAB management including prevention, control, and mitigation, and 4) Human dimensions, including public health, socio-economics, outreach, and education. Focus groups were tasked with addressing a) our current understanding based on advances since HARRNESS 2005-2015, b) identification of critical information gaps and opportunities, and c) proposed recommendations for the future. The vision statement for HARRNESS 2024-2034 has been updated, as follows: “Over the next decade, in the context of global climate change projections, HARRNESS will define the magnitude, scope, and diversity of the HAB problem in US marine, brackish and freshwaters; strengthen coordination among agencies, stakeholders, and partners; advance the development of effective research and management solutions; and build resilience to address the broad range of US HAB problems impacting vulnerable communities and ecosystems.” This will guide federal, state, local and tribal agencies and nations, researchers, industry, and other organizations over the next decade to collectively work to address HAB problems in the United States.

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