Tesi sul tema "Articulation of quantitative and qualitative methods"
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1
Crepin, Laure. "Les conséquences résidentielles des séparations conjugales : articuler les inégalités de classe et de genre dans la France contemporaine". Electronic Thesis or Diss., Paris 8, 2022. http://www.theses.fr/2022PA080024.
Abstract (sommario):
Depuis le début des années 2000, les prix immobiliers augmentent plus vite que les revenus, en particulier dans les grandes villes françaises. Les temps d’attente pour obtenir un logement social sont de plus en plus longs. Dans ce contexte, l’objet de cette thèse est d’étudier les trajectoires résidentielles des personnes ayant rompu une union cohabitante en France métropolitaine à l’aide de méthodes quantitatives (Enquêtes Logement 2002, 2006 et 2013 (INSEE) ; Statistiques sur les Ressources et les Conditions de Vie (Eurostat) (2004 – 2015) ; « Mon Quartier, Mes Voisins » (INED - CNRS Centre Max Weber, 2018)), et qualitatives (34 entretiens). Nous étudions d’abord ce que le contexte des séparations produit en termes de trajectoires sociales et résidentielles. Les ruptures peuvent participer à des trajectoires de « déclassement au cours du cycle de vie », pour celles et ceux vivant à la fois des déstabilisations professionnelles, familiales et résidentielles. Celles-ci s’articulent à des « trajectoires résidentielles descendantes », massives, en raison du contexte des séparations (déménagement dans l’urgence, baisse des ressources économiques). Nous démontrons ensuite que les ruptures conjugales participent à la croissance des inégalités de logement, inégalités selon la classe et le genre. Les ressources de l'entourage ont tendance à augmenter plutôt qu’à réduire ces inégalités. Au croisement entre sociologie du genre et des classes sociales, sociologie du logement et sociologie de la famille, cette thèse mêlant à parts égales matériaux quantitatifs et qualitatifs contribue à questionner la place du logement dans les dynamiques de la stratification socialeSince the early 2000s, real estate prices have been rising faster than incomes, especially in large French cities. Waiting times for social housing are getting longer and longer. In this context, the purpose of this thesis is to study the residential trajectories of people who have broken up a cohabiting union in metropolitan France using quantitative (Enquête Logement (Housing surveys) 2002, 2006 and 2013 (INSEE); Statistics on Income and Living Conditions (Eurostat) (2004 - 2015); "Mon Quartier, Mes Voisins" (INED - CNRS Centre Max Weber, 2018)), and qualitative methods (34 interviews). We first study what the context of separations produces in terms of social and residential trajectories. Breakups can contribute to "downgrading trajectories during the life cycle" for those who experience professional, family and residential destabilization at the same time. These are linked to massive "downward residential trajectories" due to the context of separations (emergency relocation, decline in economic resources). We then show that marital breakdowns contribute to the growth of housing inequalities, inequalities by class and gender. The resources of the entourage tend to increase rather than reduce these inequalities. At the crossroads between the sociology of gender and social classes, the sociology of housing and the sociology of the family, this thesis, which combines quantitative and qualitative materials in equal measure, contributes to questioning the place of housing in the dynamics of social stratification
2
Liu, Ting. "METHODS DEVELOPMENT IN QUALITATIVE AND QUANTITATIVE PROTEOMICS". UKnowledge, 2008. http://uknowledge.uky.edu/gradschool_diss/838.
Abstract (sommario):
Proteomics based on liquid chromatography coupled to mass spectrometry has developed rapidly in the last decade and become a powerful tool for protein mixtures analysis. LC-MS based proteomics involves four steps, sample preparation, liquid chromatography, mass spectrometry and bioinformatics. Improvements in each step have extended its applications to new biological research areas. This dissertation mainly focuses on method developments in both qualitative and quantitative proteomics.
The first part of this dissertation focuses on qualitative analysis of T. gondii Parasitophorous Vacuole Membrane (PVM) proteins, which is very important for T. gondii’s survival. The hypothesis of this study is that proteomic approaches coupled with immunoprecipitation using polyclonal antisera as affinity reagents can successfully characterize the proteome of the T. gondii PVM. The “Three-layer Sandwich Gel Electrophoresis” (TSGE) protocol, was developed to contend with efficient salt removal and protein concentration from challenging samples. Furthermore, the TSGE coupled to 2D-LC-MS/MS was proven to be effective with the proteomic analysis of complex protein mixtures like T. gondii whole cell lysate, allowing for high-throughput protein analysis from complex samples. By using the TSGE-2D-LC-MS/MS methodology, we successfully identified 61 proteins from the PVM samples and constructed the PVM proteome.
The second part of this dissertation describes a novel method for selecting an appropriate isocyanate reagent for potential quantitative proteomics application. Our hypothesis is alteration of isocyanate structure will change fragmentation pattern and ESI property of isocyanate modified peptides. The CID property of N-terminal modified peptides by phenyl isocyanate (PIC), phenethyl isocyanate (PEIC) and pyridine-3- isocyanate (PyIC) was systematically studied using LC-ESI-MS/MS. We observed that adjustment of isocyanate structure changed both ESI and fragmentation characteristic of modified peptides. We rationalized the decrease of protonation of PIC and PEIC modified peptides results from the neutral property of the both reagents. The electron withdrawing feature of PyIC leads to significant reduction of fragments during CID. Therefore, we designed a new isocyanate reagent, 3-(isocyanatomethyl) pyridine (PyMIC). The results revealed that PyMIC modified peptides had more suitable ESI properties and generated more sequence-useful fragments compared to PIC, PyIC and even unmodified peptides. PyMIC is a more appropriate labeling reagent for quantitative proteomics applications.
3
Liao, Yi-Hui. "Profiling caesarean birth in Taiwan using quantitative and qualitative methods". Thesis, University of Ulster, 2009. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.514479.
4
Wang, Kai. "Novel computational methods for accurate quantitative and qualitative protein function prediction /". Thesis, Connect to this title online; UW restricted, 2005. http://hdl.handle.net/1773/11488.
5
Gao, Yang. "On the integration of qualitative and quantitative methods in data fusion". Thesis, University of Oxford, 1994. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.240463.
6
Weigel, Annalisa L. (Annalisa Lynn) 1972. "Bringing policy into space systems conceptual design : qualitative and quantitative methods". Thesis, Massachusetts Institute of Technology, 2002. http://hdl.handle.net/1721.1/29214.
Abstract (sommario):
Thesis (Ph. D.)--Massachusetts Institute of Technology, Engineering Systems Division, Technology, Management, and Policy Program, 2002.Includes bibliographical references (p. 165-168).
A change in government policy can send waves of crippling impacts through the design and development of publicly funded complex engineering systems. Thus it is important for system architects and designers to understand the interaction of policy with their systems, and to strive for policy robustness in their systems. To be policy robust is to successfully pass through policy changes that might arise during the course of system development in order to bring the system into operational use. The goal of this thesis research is to enable the creation of policy robust system architectures and designs through making policy an active consideration in the engineering systems architecting and design process. Qualitative and quantitative analysis methods are brought to bear on the problem using space systems as the application domain, and a process is set down through which policy can become an active consideration instead of a static constraint. Unique contributions of this thesis in the qualitative analysis of policy robust systems include new heuristics describing the interaction of policy and publicly funded engineering systems, as well as impact flow path diagrams for tracing policy interactions with technical engineering system parameters. Quantitative contributions include general relationships for the behavior of engineering system architecture sets under downward annual budget policy pressure, and the application of real options to measure the value of designing an engineering system to be policy robust to budget policy instabilities. Lastly, this research presents the first comprehensive quantification of U.S. space launch policy economic costs, and contributes relationships for estimating these costs on new space systems.
(cont.) The analysis techniques presented in this thesis for assessing and insuring policy robustness can be applied as early as the conceptualization phase of system architecting and design, and the earlier they are applied in the process, the greater the benefits that can be derived. As the architecture and system design solidify, time and opportunities are lost to tailor a system for policy robustness.
by Annalisa L. Weigel.
Ph.D.
7
ROSANO, MARIANGELA. "Mixing quantitative and qualitative methods for sustainable transportation in Smart Cities". Doctoral thesis, Politecnico di Torino, 2019. http://hdl.handle.net/11583/2744154.
8
Perry, Michelle P. A. "Combining quantitative and qualitative methods in signal detection and evaluation in pharmacovigilance". Thesis, University of Portsmouth, 2014. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.618567.
Abstract (sommario):
Background: Pharmacovigilance (PV) is the science and activities involved in monitoring and developing the safety profile of all marketed medicines. Adverse drug reactions (ADRs) for medicinal products can be identified through postmarketing studies by methods of signal detection. Traditional, qualitative methods involve clinical review of cases, and coupled with modem, quantitative methods which have evolved as PV has grown, may help surveillance of the large number of medicinal products on the market today. This research aimed to investigate combining traditional and modern methods of signal detection by adding statistical weighting to adverse event telms identified as requiring further monitoring pre-marketing, to improve identification and evaluation of ADRs post -marketing. Methods: Four anti-diabetic drugs currently marketed were chosen to model the concept: gliclazide, pioglitazone, rosiglitazone and vildagllptin. Review of pre-marketing information for safety concerns highlighted two medical concepts: cardiac failure and acute pancreatitis. The Delphi method was adapted to identify and pliolitise terms for these concepts to add statistical weighting to. The weightings were applied to two datasets, both from the UK Yellow Card. Scheme (YCS): a two-year dataset (2005-2007) and a ten-year dataset (2000- 2010).
9
Wiggins, Bradford J. "The Dilemma of Mixed Methods". BYU ScholarsArchive, 2011. https://scholarsarchive.byu.edu/etd/2810.
Abstract (sommario):
The past three decades have seen a proliferation of research methods, both quantitative and qualitative, available to psychologists. Whereas some scholars have claimed that qualitative and quantitative methods are inherently opposed, recently many more researchers have argued in favor of "mixed methods" approaches. In this dissertation I begin with a review of the mixed methods literature regarding how to integrate qualitative and quantitative methodologies. Based on this review, I argue that current mixed methods approaches have fallen short of their goal of integrating qualitative and quantitative methodologies and I argue that this problem may be due to a problematic ontology. In response to this problem I propose and conduct an ontological analysis, which examines the writings of leading mixed methods researchers for evidence of an underlying ontology. This analysis reveals that an abstractionist ontology underlies current mixed methods approaches. I then propose that an alternative relational ontology might better enable mixed methods researchers to meaningfully relate qualitative and quantitative methodologies and I provide an exploration of what assuming a relational ontology would mean for mixed methods research.
10
Barnett, Inka. "Physical activity and the transition to retirement : combining quantitative and qualitative research methods". Thesis, University of Cambridge, 2013. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.648141.
11
Hickenbottom, Sabrina. "Progressive methods utilized in the qualitative and quantitative analysis of human carotenoid metabolism /". For electronic version search Digital dissertations database. Restricted to UC campuses. Access is free to UC campus dissertations, 2002. http://uclibs.org/PID/11984.
12
Sonday, Farhaana. "Medicine therapy management for diabetic club Patients at a primary health care clinic: exploring a Potential role for pharmacists". University of the Western Cape, 2019. http://hdl.handle.net/11394/7479.
Abstract (sommario):
Magister Pharmaceuticae - MPharmDiabetes mellitus is a complex chronic condition and has become a major public health concern worldwide. Many diabetic patients are accessing primary health care (PHC) clinics for diabetes care. Diabetic patients who are considered stable are referred to chronic diseases of lifestyle club at the PHC facility. Effective management of this chronic condition requires a multidisciplinary team approach to diabetes care. Pharmacists are not often included in a multidisciplinary team and would consist of doctors, nurses and dieticians. Teams may be expanded and require specialist healthcare members’ expertise who can assist in the management of this disease, for example, ophthalmologists and podiatrists. Adherence to standard treatment guidelines (STGs) for the management of diabetes by healthcare professionals at a primary care level can improve glycemic control, decrease health costs and reduce the development of long-term diabetic complications.
13
Pakbaz, Mojgan. "Vaginal prolapse – clinical outcomes and patients’ perspectives : a study using quantitative and qualitative methods". Doctoral thesis, Umeå universitet, Obstetrik och gynekologi, 2011. http://urn.kb.se/resolve?urn=urn:nbn:se:umu:diva-40613.
Abstract (sommario):
Background: Pelvic organ prolapse (POP) is a relatively common condition. In Sweden, the overall estimated prevalence of POP in the female population is 31% and the prevalence of symptomatic prolapse is 8–15%. The prevalence of POP increases with age. The lifetime risk of undergoing pelvic floor surgery is estimated to 11%. The aim of this thesis was to investigate outcomes of vaginal hysterectomy for treatment of prolapse; to study outcomes of cystocele repair surgery and patient satisfaction related to different anaesthesia methods; to explore women’s experiences of vaginal prolapse; and to investigate what is known regarding POP prior to surgery and healthcare-seeking behaviour. Methods: In the Swedish National Quality Register for Gynaecological Surgery (Gynop-register), 941 women were identified who underwent vaginal hysterectomy for prolapse from 1997 to 2005 and 1,364 women were identified who underwent cystocele repair surgery from 2006 to 2009. In-depth interviews were performed with 14 women with vaginal prolapse. Interview data were analyzed with a qualitative content analysis. To investigate women’s knowledge about POP and healthcare-seeking behaviour, a questionnaire was developed, validated and distributed to women with planned surgery for POP. Women undergoing hysterectomy or incontinence surgery were used as reference groups. Results: Severe complications after vaginal hysterectomy occurred in 3% of cases. Sexual activity was improved after vaginal hysterectomy, the number of women reported to have intercourse increased by 20% (p = 0.006). Subjective symptoms of urinary incontinence and overactive bladder were resolved in 50% of the women. De novo stress incontinence was reported by 11% of the women. Use of local anaesthesia (LA) in reconstruction of cystocele showed advantage over other forms of anaesthesia. Length of hospital stay, duration of use of postoperative pain-killing drugs, and time to return to daily activity were shorter among women who underwent surgery with LA compared to other forms of anaesthesia. Patient satisfaction was not related to methods of anaesthesia. In an interview study, the process from recognition the symptoms to seeking healthcare was highlighted. Two categories, “obstacles” and “facilitators” to seeking health care, were identified. One of the obstacles was lack of information on POP in the public domain. The main facilitators were feeling sexually unattractive and impaired physical ability due to POP. Some findings from the interview study were further explored in the questionnaire study. One out of five women with vaginal prolapse did not know that the symptoms were related to prolapse before consulting their physician. Over 30% of the women in the incontinence group were embarrassed to talk about incontinence, and they were unaware that it could be treated. The most frequent description of vaginal prolapse was vaginal bulging. Women in the prolapse group had significantly less access to information through brochures and public media than women in the incontinence group (p < 0.001). Conclusion: Short-term follow-up after vaginal hysterectomy showed that sexual activity and urinary symptoms had improved. Cystocele surgery using LA showed no disadvantage compared to surgery using other anaesthesia methods. POP surgery can therefore be performed safely with LA. Information on prolapse should be easily accessible to improve the possibility for women of gaining knowledge and thereby overcoming obstacles to seeking medical advice. Healthcare professionals have a significant role to play in informing women about symptoms and available treatment options.
14
Wright, Kacie LaRae. "A Comparison of Qualitative and Quantitative White Matter Methods in Pediatric Traumatic Brain Injury". BYU ScholarsArchive, 2018. https://scholarsarchive.byu.edu/etd/7384.
Abstract (sommario):
Magnetic resonance imaging is used to assess white matter (WM) abnormalities including total WM volumes and WM hyperintensities (WMHs). Comparisons between several qualitative and quantitative methods to assess WM that are used in research and clinical settings are lacking in pediatric traumatic brain injury (TBI). This study 1) WM methods including Scheltens ratings, manual tracings, NeuroQuant®, and FreeSurfer; (2) compared total WM volumes and WMHs to assess potentially similar reporting of WM integrity; and (3) assessed the relationship between cognitive functions (intelligence, attention, processing speed, and language) and WM in pediatric TBI.Sixty participants (65% male) between ages 8-13 years old, had a complicated-mild (53%), moderate (15%), or severe TBI (32%) with a mean age of 2.6 at the time of injury. NeuroQuant® WMH volumes had poor agreement (ICC = .24), and did not correlate (r = .12, p = .21) with manually traced WMH volumes. Scheltens WMH ratings had good to excellent agreement and correlated with NeuroQuant® (ICC = .62; r = .29, p = .005) and manually traced WMH volumes (ICC = .82; r = .50, p = .000). NeuroQuant® and FreeSurfer total WM volumes had fair agreement and were correlated (ICC = .52; r = .38, p = .004). No significant difference in total WM volumes were found between complicated-mild and moderate-severe TBI groups, and in subgroups with and without WMHs. Processing speed was significantly associated with Scheltens WMH ratings: p = .004, manually traced WMHs: p = .002, and NeuroQuant® WMHs: p = .007. No other association between cognitive functions and WM volumes or hyperintensities were found. Correlations between NeuroQuant® and manual tracings with processing speed differed by sex, where males had significant correlations but females did not. Deciding when to use manual tracing and NeuroQuant® WMH volumes and Scheltens ratings in clinical or research settings will depend on available resources (e.g., time, technology, funding, and expertise) and purpose of assessing WMHs. Total WM volumes did not appear to capture WM pathology as assessed by WMHs, likely due to the sample being underpowered and that total WM volumes possibly included WMHs. Limitations include restricted range of injury severity, heterogeneity of lesions, and small sample size. Additional research is needed in a larger sample of pediatric TBI.
15
Baranowska-Rataj, Anna, Anna Matysiak e Monika Mynarska. "Does Lone Motherhood Decrease Women's Happiness? Evidence from Qualitative and Quantitative Research". Springer Nature, 2014. http://dx.doi.org/10.1007/s10902-013-9486-z.
Abstract (sommario):
This paper contributes to the discussion on the effects of single motherhood on
happiness. We use a mixed-method approach. First, based on indepth interviews with
mothers who gave birth while single, we explore mechanisms through which children may
influence mothers' happiness. In a second step, we analyze panel survey data to quantify
this influence. Our results leave no doubt that, while raising a child outside of marriage
poses many challenges, parenthood has some positive influence on a lone mother's life.
Our qualitative evidence shows that children are a central point in an unmarried woman's
life, and that many life decisions are taken with consideration of the child's welfare,
including escaping from pathological relationships. Our quantitative evidence shows that,
although the general level of happiness among unmarried women is lower than among their
married counterparts, raising a child does not have a negative impact on their happiness.
16
Fowler, Philip William. "Qualitative and quantitative aspects of biomolecular systems revealed by large scale and grid computing methods". Thesis, University College London (University of London), 2006. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.430877.
17
Vroegop, John. "Nature Connectedness & Winter Camping : A Combination of Quantitative and Qualitative Approaches". Thesis, Linköpings universitet, Nationellt centrum för utomhuspedagogik (NCU), 2015. http://urn.kb.se/resolve?urn=urn:nbn:se:liu:diva-120253.
Abstract (sommario):
A growing body of research indicates that nature connectedness should be an important component of environmental education programs as emerging empirical evidence shows a correlation between connectedness to nature and environmentally responsible behaviour. Despite an increased interest in further examination of the human-nature relationship, research is lacking in terms of specific factors or conditions that influence nature connectedness. In this study, a mixed methods approach was employed to quantitatively assess the impact winter camping had on nature connectedness and then qualitatively determine specific components of the camp experience that influenced this sense of nature connectedness. Nineteen scouts participated on a three day winter camp at Manning Park in British Columba, Canada, where they experienced many challenges such as sleeping in quinzees (snow caves) and learned new skills such as snowshoeing. The Nature Relatedness Scale was used to assess nature connectedness in this study. A pre-test was administered a few days before the winter camp and the post-test two days afterwards. The results from the paired sample T-test show that there was a statistically significant improvement in nature connectedness following the winter camp experience. Eleven scouts were then selected to participate in semi-structured interviews with the aim of gaining insight to the specific conditions of winter camping that influenced nature connectedness. The results indicate that the location of the camp, the condition of being immersed in nature, interacting with wildlife, the positive experience of challenges, the presence of risk, and freedom from technology are all contributing factors that influenced a sense o f nature connectedness. An increased environmental awareness was also a prevalent theme which supports research suggesting that there is a positive relationship between nature connectedness and pro-environmental behaviour. It is recommended that programs with the aim of promoting nature connectedness or environmental awareness should include as many of these components as possible. Further research should alsobe conducted to confirm that these results apply also to other populations as these results cannot be generalized with a sample size of nineteen.
18
Schulze, S., e G. Kamper. "The use of mixed methods as reflected in two eminent South African educational research journals". Journal for New Generation Sciences, Vol 10, Issue 1: Central University of Technology, Free State, Bloemfontein, 2012. http://hdl.handle.net/11462/603.
Abstract (sommario):
Published ArticleThe epistemological and ontological orientations relevant for this research are positivism, interpretivism and pragmatism. These paradigms of inquiry are associated with quantitatively oriented research traditions, qualitatively oriented research traditions and mixed methods research respectively. Researchers who use mixed methods build on the strengths of quantitative and qualitative methods and minimize their weaknesses. Since educational research is primarily evidence-based, the aim of the study was to explore the extent to which mixed methods research was reflected in two eminent South African educational research journals during the 11 year period, 2000 to 2010. To this end 1392 articles were analysed. Of the research articles published in the two journals, 17.8% and 15.1% respectively reported on the use of mixed methods. Quantitative methods dominated between 2000 and 2002, followed by a paradigm war in 2003 to 2007, and mainly qualitative methods from 2008 onwards. Mixed methods research was mostly used in the educational domains of didactics (inclusive of curriculum studies), management and social studies. The most dominant themes investigated in these fields were related to curricula and the NQF/OBE, transformation, staff diversity, e-learning and other teaching methods. The need to develop mixed methods research in all branches of social research in South Africa is indicated.
19
Bullock, Steven David. "Integrating Quantitative and Qualitative Research Methods to Inform Management of the Cadillac Mountain Summit, Acadia National Park". Thesis, Virginia Tech, 2006. http://hdl.handle.net/10919/34144.
Abstract (sommario):
Included in this thesis are two papers describing companion studies which employed complementary methodologies to study the issue of how Acadia National Park might balance resource protection efforts and maintain quality visitor experiences on the summit of Cadillac Mountain. In the first study, stated choice analysis was used to assess visitors' preferences for alternative combinations of public access, resource protection, visitor regulation, and site hardening to manage the Cadillac Mountain summit. Results suggest that visitors consider resource protection to be a priority and are willing to accept regulation of their behavior onsite, reinforced with the use of moderately to highly intensive management structures, but generally don't support limiting public access to the summit to achieve resource protection objectives. In the second study, qualitative interviews were conducted to provide an in-depth understanding of visitor experiences on the summit of Cadillac Mountain and how site management actions designed to achieve resource protection objectives might affect visitors' experiences. Respondents indicated that the summit of Cadillac Mountain is a centerpiece of Acadia National Park, and their experiences of the mountain summit are centered around the aesthetics and naturalness of Cadillac Mountain. Several factors emerged as influencing whether site management actions are deemed appropriate by visitors and perceived to affect visitors' experiences. In particular, site management structures that were perceived to blend in with the surroundings, be constructed of natural materials and protect vegetation were considered appropriate and of little consequence to visitors' experiences. Some study participants also suggested that site management structures that provide visitors with the opportunity to freely demonstrate their choice to help protect vegetation and soils can enhance visitors' experiences. In contrast, site management structures and actions perceived as being regulatory, confining, or limiting opportunities for visitors to choose to help protect vegetation resources were considered less appropriate and more likely to negatively affect visitors' experiences.Master of Science
20
Porter, Catherine Sarah. "Mapping spaces : towards a quantitative methodology for exploring maps and mapping in early modern Ireland, c.1530-1610". Thesis, Queen's University Belfast, 2014. https://pure.qub.ac.uk/portal/en/theses/mapping-spaces-towards-a-quantitative-methodology-for-exploring-maps-and-mapping-in-early-modern-ireland-c15301610(5d58fa90-00c1-4a2f-ae67-ff752c07452b).html.
Abstract (sommario):
This thesis assesses the evolution of historic maps of Ireland using Geographic Information Systems (GIS) and quantitative approaches. Each of nineteen early modern maps dating to the sixteenth and early seventeenth centuries (c.1530 – 1610), a formative period of Irish cartographic history, was analysed to statistically assess the relative positional accuracy of places included on the cartography. Building upon previous studies of analysing cartographic veracity using quantitative approaches, notably Tobler's (1994) bidimensional regression technique, it is the first of its kind to apply these techniques to a series of historic maps. The aim is to test these approaches systematically and critically, compare the statistical techniques, and offer insights into their analytical potential in the history of cartography and historical geography. The thesis also aims to enhance our understanding of the evolution and development of maps and map-making during an age often regarded as revolutionary in scientific cartography in Europe. The study highlighted two main historical and cartographic groups; (I) earlier maps of Ireland created prior to Lythe’s survey cartography in which mapmakers appeared to take a more artistic rather than a ‘measured’ approach to mapping and; (II) maps created subsequent to Lythe’s and of generally higher cartographic precision in illustrating the island's geography. Enduring map ‘errors’ that survived through to the seventeenth century are discussed, and illustrate that the development of maps of Ireland did not progress in a linear fashion. Map lineage was complex, and plagiarism between mapmakers was rife with one map, by Robert Lythe (PHA 9581, c.1571), shown to form the basis for many subsequent maps. The methodology developed in this thesis is a fundamental addition to early map research, by adding to key debates in the history of cartography concerned with how early maps developed and evolved, and providing new insights on Ireland’s early cartography.
21
Campbell, Ian. "Development of optical based characterisation and detection methods for quantitative and qualitative assessment of phytoplankton in their natural environment". Thesis, Robert Gordon University, 2000. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.325446.
22
Litten, Joyce A. Puracchio. "A Quantitative and Qualitative Inquiry into the Call to Serve Among Non-Traditional Undergraduate Social Work Students". Bowling Green State University / OhioLINK, 2008. http://rave.ohiolink.edu/etdc/view?acc_num=bgsu1213981151.
23
Castrillo, Marta R. "Evaluating the effects of context in the use of two downtown Tucson urban plazas using qualitative and quantitative approaches". Thesis, The University of Arizona, 2000. http://hdl.handle.net/10150/278754.
Abstract (sommario):
Urban plazas, together with streets, and parks, constitute the remaining public realm of our cities. Their function, as facilitators of social interaction, is most evident in areas where urban structure still prevails in relation to pedestrian use. Since pedestrians represent the majority of potential users, use of these spaces is intimately related to surrounding population and activities, and may be affected by how the immediate context is configured. This study examined two urban plazas in downtown Tucson, with their context, to develop methods of analysis and evaluation of potential effects of contextual elements in their use. Overall, this study found that combination of qualitative and quantitative approaches was useful in the generation of data, as well as analytical tools. Although this study's results are limited to the spaces analyzed, potential relationships are suggested between aspects of plaza use and specific elements of the human and physical context.
24
Wakelin, Sarah Catherine. "A quantitative and qualitative assessment of stormwater retention basisns, relationships in nature and response to three aquatic weed control methods". Thesis, National Library of Canada = Bibliothèque nationale du Canada, 1999. http://www.collectionscanada.ca/obj/s4/f2/dsk1/tape8/PQDD_0014/MQ41645.pdf.
25
Franco, Placido <1990>. "Development of innovative chromatography-mass spectrometry analytical methods for the qualitative and quantitative determination of target analytes in complex matrices". Doctoral thesis, Alma Mater Studiorum - Università di Bologna, 2018. http://amsdottorato.unibo.it/8488/1/PhD%20Thesis.pdf.
Abstract (sommario):
The present thesis deals with the development of chromatography-mass spectrometry analytical methods for the analysis of target molecules in complex matrices. These compounds have different applications, ranging from nutraceutical to pharmaceutical or archaeological. Generally, the main aim was to provide accurate quantification of one or several analytes within real samples and then, in order to fulfil the requested standards, several efforts have been put on the development and validation of specific analytical methods, suitable for the system under investigation. The developed methods proved to be able to face the analytical challenges raised by the presence of complex matrices able to interfere with the accuracy of the result and the data interpretation.
During the first year of PhD, my research focused on the analysis of glucosinolates, compounds occurring in the plants of Brassica order. Glucosinolate metabolism leads to compounds called isothiocyanates, known for their anticancer activity. Glucosinolates and isothiocyanates are compounds of strong interest for nutraceutical applications and functional food development, while their analysis is important for the evaluation of the product quality, especially in terms of available amount and stability.
Another important project involved the in vivo evaluation of the biodistribution and metabolism of obeticholic acid in a cirrhosis induced rat model. Considering that obeticholic acid has been recently approved for the treatment of cirrhosis, the importance of this study resides in the necessity to assess a safety profile in case of administration to patients with liver diseases, where dangerous accumulation or unexpected metabolites might occur as consequence of the liver impairment.
During my third year of PhD, I worked on the target analysis of different lipid classes in archaeological samples. The determination of specific biomarkers in archaeological finds, indeed, is important because it can address historical questions about past diets, ancient practices, but also vessel production and related use.
26
Drumheller, Dolores. "Information Withholding and the Management of Productivity in Teams". ScholarWorks, 2011. https://scholarworks.waldenu.edu/dissertations/1059.
Abstract (sommario):
The importance of good communications between team members has been well documented. Yet previous studies on communications between team members have neglected to focus on reasons for information withholding between people working on teams. The purpose of this case study of 16 engineers and 6 educators was to understand why team members withhold information when working together. A convenience sample was selected from a software engineering organization. Collective intelligence theory in a modern communications environment was used as the theoretical foundation. This theory posits that the synergy of full group collaboration results in enhanced performance and the spread of new ideas. The exploratory research questions addressed in this study were designed to understand how employees decide what information to withhold when participating on teams; how withholding information is influenced by critical thinking, creativity, positions on a team, and type of employee; and the effects of information withholding. Collected data from online interviews were transcribed and validated via member checks, coded using open and axial coding, and analyzed. Seven themes were found: insecurity, gate keeping, discrimination, personality, creativity, organizational structure, and team management. The results of this study may provide information that can help managers understand employees' experiences with, reactions to, and opinions about information withholding and provide strategies to create an environment in which team members do not withhold information from each other, thus improving or enhancing positive social change in organizations.
27
Savage, Beth Ann. "A Qualitative Exploration of the Security Practices of Registered Nurses". ScholarWorks, 2017. https://scholarworks.waldenu.edu/dissertations/3722.
Abstract (sommario):
Increased breach occurrences in healthcare cause concern for health information as reported by the Federal Government. Significant effort, regulations, and safeguards are in place to protect the systems used in the healthcare industry. Employee handling of security remains an area of vulnerability related to security protocols. The unified theory of acceptance and usage of technology (UTAUT) served as the model for this qualitative exploratory study with the purpose of understanding registered nurse (RN) perceptions and lived experiences related to IT security. Face-to-face interviews were conducted with 20 participants from the Three Rivers Chapter American Association Critical Care Nurses. Transcribed data were analyzed with a priori codes aligned to the constructs of UTAUT and emergent themes. The emergent themes from the RNs' lived experiences revealed perceptions of IT security mishandling, including walking away from the computer without log-off, and sharing of accounts through single sign on authenticated badges. Strategic planning for the organizational IT security may be strengthened due to the insight about the RNs' workflow related to IT security. Understanding employee perceptions, expressed intentions, and self-reported behaviors to IT security allows for the ability as managers to apply that knowledge to IT security systems, access methods, and implement procedures that will provide for increased organizational IT security and increased patient confidence. The social change from this work may provide contributions to the development of IT infrastructure systems for healthcare helping to create and maintain continued access to and availability of electronic medical records and data for increasing numbers of people who need health maintenance and care.
28
Taylor, Richard Ian. "Agent-based modelling incorporating qualitative and quantitative methods : a case study investigating the impact of e-commerce upont the value chain". Thesis, Manchester Metropolitan University, 2003. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.400939.
29
Sandbrook, Sandra. "Love or protection? : defining and measuring maternal-fetal attachment from the woman's perspective". Thesis, University of Wolverhampton, 2009. http://hdl.handle.net/2436/90893.
Abstract (sommario):
Existing commonly used maternal-fetal attachment instruments have not been thoroughly tested for reliability and validity; criticism can be levelled for a variety of problems ranging from lack of reliability due to an inadequate underpinning framework to facilitate objective interpretation to limited generalizability due to the sample. The aim of this study is to acknowledge the centrality of the mother, to use the experiences of pregnant women to generate a definition of maternalfetal attachment and ultimately create a tool that will act as a reliable, valid and simple measurement. A mixed method framework utilising a sequential exploratory strategy has allowed qualitative exploration of the phenomenon under investigation followed by quantitative testing of the emerging theory on a much larger and different sample. Phase 1 involved face to face open structured interviews on an opportunity sample of 10 (5 primigravid; 5 multiparous) women in the final trimester of pregnancy followed by 3 focus groups targeting specific groups – primigravid women (6 participants); multiparous women (7 participants) and teenagers (4 participants). Data analysis was through constant comparative methodology. A multidimensional, psycho-biological definition of attachment was generated from the women’s own perception of their attachment to their fetus. This was used as a framework to design a questionnaire for the measurement of maternal-fetal attachment. Phase 2 involved the validation of the questionnaire and further testing of the definition. Cohort 1 tested for reliability with 200 participants within their second or third trimester of pregnancy. Following modification of the questionnaire, Cohort 2 a sample of 150 women within the final trimester of pregnancy tested the tool for internal reliability and validity. The generated Maternal-Fetal Attachment Tool (MFAT) following rigorous testing proved both reliable and valid. Maternal fetal attachment is founded in psycho-biological theory and is a complex multi-dimensional construct. Central to the definition is the woman’s need to protect her fetus, attachment develops as the fetus becomes more tangible, it is facilitated through the woman’s intergenerational experience of attachment and through appropriate social support. Maternal-fetal attachment facilitates behavioural change to ensure a favourable intra-uterine environment.
30
Hartung, Julie A. "“It’s never going to be perfect even though I want it to be”: Quantitatively and qualitatively investigating honors and non-honors students’ experiences of perfectionism and related variables". Digital Commons @ East Tennessee State University, 2021. https://dc.etsu.edu/honors/631.
Abstract (sommario):
Previous research has demonstrated that students in university honors programs may be distinct from their non-honors counterparts. To further examine these differences and the overall experiences of honors students, this thesis utilized a Study 1/Study 2 mixed methodology design to examine the experiences of honors students within East Tennessee State University’s University Honors Scholars program. Study One quantitatively examined the differences between honors and non-honors students’ levels of perfectionism, imposter syndrome, and academic and social competitiveness. Findings from Study One inspired Study Two, which qualitatively examined honors students’ experiences with perfectionism, uncovering the sources and effects of their perfectionistic behaviors. Combined, these findings indicate that not only do honors students experience higher levels of perfectionism than non-honors students, likely stemming from the expectations and standards held by the honors program, but also that their perfectionistic behaviors are overall maladaptive and are used to avoid failure rather than in the pursuit of success.
31
Loliwe, Thando. "The effect of reporting incentives on International Financial Reporting Standards compliance by unlisted companies in South Africa: using qualitative and quantitative methods". Doctoral thesis, University of Cape Town, 2018. http://hdl.handle.net/11427/29332.
Abstract (sommario):
This dissertation investigates the factors which influence unlisted companies’ compliance with International Financial Reporting Standards (IFRS) in South Africa at three levels: the global level, the country level, and the company level. This dissertation also considers whether taking such factors into account in the standard-setting process would lead to improved IFRS compliance. This dissertation applies a multiple case study method followed by a national wide survey. Thus, the data were collected by reading the IFRS, and through questionnaires and interviews. A total of 41 companies responded to the survey while five (5) companies participated in the case study. This dissertation’s main findings show that at company level, governance and financial people working for these companies are significant factors which influence their IFRS compliance. Further, non-auditing and/or non-accounting companies are highly reliant on their external auditors in order to comply with the IFRS. The findings also show that at country level, economic, legal, cultural and professional factors influence these companies’ IFRS compliance. At global level, the findings show that the international recognition of IFRS, transparency, comparability, understandability, foreign operations, and importing and exporting are the factors which influence these companies’ IFRS compliance. There are several contributions that can be attributed to this dissertation. First, this dissertation contributes to the literature by extending the research regarding factors (or some indicators for factors) which influence unlisted companies’ IFRS compliance and these companies’ experience of using IFRS in South Africa. Further, this dissertation suggests a model which explains those indicators which appear to influence unlisted companies’ IFRS use at company level. Second, this dissertation contributes to the literature by testing five theories (these are, decision usefulness theory, agency theory, stewardship theory, stakeholder theory and institutional theory) on unlisted companies. Third, this dissertation’s original contribution is to use a self-prophecy effect to gain a better understanding of unlisted companies’ predicted continuing use of IFRS.
32
Fee, Craig. "Causes of Burnout Among Church Leaders: A Qualitative Phenomenological Study of Pastors". ScholarWorks, 2018. https://scholarworks.waldenu.edu/dissertations/5077.
Abstract (sommario):
After 30 plus years of research, clergy burnout is an ongoing concern; as such, it is important to identify the causes of this phenomenon. Researchers have already demonstrated that internal factors such as personality types, personal mastery, or conflict management and external factors such as role conflict, excessive activities, or unrealistic expectations, can lead to burnout. The problem that led to this study was that more exploration is needed about clergy's perceptions on leadership and burnout within the church. The purpose of this qualitative phenomenological study was to explore clergy within the Wesleyan Church in the Midwest to discover their perceptions about leadership and burnout within the church. The conceptual framework was shaped by the great man theory of leadership and Maslach's burnout theory. The central research question for this study focused on clergy's perceptions about leadership and burnout within the church. Data were collected using face-to-face semistructured interviews with 23 pastors who are currently leading and experiencing burnout. Data collected included transcribed interviews, field notes, and observations. Data were hand-coded to find key concepts and themes. Two themes that emerged from the data were leadership is understood as hierarchical and leadership is understood as the work of solo actors, which were consistent with the great man theory of leadership. The results of this study may contribute to a better understanding of the factors that lead to clergy burnout. The results of this study will address a gap in literature and may result in positive social change for both the clergy and church congregants because the results can be used to come up with solutions for burnout. This study may also lead to new theories about clergy burnout.
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Gabriel, Pedro Hugo do Nascimento. "Software languages engineering: experimental evaluation". Master's thesis, Faculdade de Ciências e Tecnologia, 2010. http://hdl.handle.net/10362/4854.
Abstract (sommario):
Dissertação apresentada na Faculdade de Ciências e Tecnologia da Universidade Nova de Lisboa para obtenção do grau de Mestre em Engenharia InformáticaDomain-Specific Languages (DSLs) are programming languages that offer, through appropriate notation and abstraction, still enough an expressive control over a particular problem domain for more restricted use. They are expected to contribute with an enhancement of productivity, reliability, maintainability and portability, when compared with General Purpose Programming Languages (GPLs). However, like in any Software Product without passing by all development stages namely Domain Analysis, Design, Implementation and Evaluation, some of the DSLs’ alleged advantages may be impossible to be achieved with a significant level of satisfaction. This may lead to the production of inadequate or inefficient languages. This dissertation is focused on the Evaluation phase. To characterize DSL community commitment concerning Evaluation, we conducted a systematic review. The review covered publications in the main fora dedicated to DSLs from 2001 to 2008, and allowed to analyse and classify papers with respect to the validation efforts conducted by DSLs’ producers, where have been observed a reduced concern to this matter. Another important outcome that has been identified is the absence of a concrete approach to the evaluation of DSLs, which would allow a sound assessment of the actual improvements brought by the usage of DSLs. Therefore, the main goal of this dissertation concerns the production of a Systematic Evaluation Methodology for DSLs. To achieve this objective, has been carried out the major techniques used in Experimental Software Engineering and Usability Engineering context. The proposed methodology was validated with its use in several case studies, whereupon DSLs evaluation has been made in accordance with this methodology.
34
Loik, Nikita D. "Development and application of methods for qualitative and quantitative analysis of amino acid post-translational modifications using liquid chromatography coupled to mass spectrometry". Thesis, University of Oxford, 2014. http://ora.ox.ac.uk/objects/uuid:8c737f3c-b24d-437d-abac-bada61351173.
Abstract (sommario):
The 2-oxoglutarate and ferrous ion dependent oxygenases are a super family of enzymes that are involved in a wide range of biological processes regulated trough the mechanism of post-translational modification (PTM). Such biological processes include hypoxia sensing (through regulating HIF transcription), fatty acid metabolism (through carnitine production), transcriptional regulation (through demethylation of histones), and collagen structure formation (through proline and lysine hydroxylation). To understand the underlying mechanisms of such regulatory processes, and to develop clinically useful inhibitors, and thereby regulate these processes in living organisms, requires sensitive methods for monitoring enzyme activity. The use of indirect methods such as quantification of reaction products (14CO2 or succinate) can be problematic, as both products can result from competitive reactions. Alternative direct measurement of substrate modifications using mass spectrometry-based proteomics can be applied; however, (1) for this technique the limit of detection is often prohibitive, (2) the method is best suited for the confirmation of known modifications, rather than for the discovery of new modifications, and (3) sequence coverage may often be only 60%, and therefore many modifications can be missed. The aim of the research presented in this thesis was to develop amino acid analysis and to apply these methods to the identification and quantification of PTMs catalysed by 2-oxoglutarate and ferrous ion dependent oxygenases. A range of LC-MS approaches were investigated including: (1) C18 reversed phase chromatography of quinoline derivatised amino acids, (2) ion paring chromatography, and (3) mixed mode chromatography with either UV, or conventional molecular MS, or isotope ratio mass spectrometry detection. Analysis of the elution patterns for those separation techniques enabled estimation of the retention parameters of modified amino acids and the identification of the modifications, where no standards were available. The most sensitive approach developed employed mixed mode chromatography coupled to isotope ratio mass spectrometry which was optimised for the analysis of modified amino acids. This was shown to have a limit of detection two orders of magnitude lower (0.01μM) than other conventional mass spectrometry techniques. Using amino acid labelling in cell culture, a quantification protocol was developed which employed a non-labelled internal standard and selectively labelled cell culture. The method was shown to be suitable for both very accurate quantification at low concentration levels and metabolic studies, allowing us to track back the modifications to their precursors. The analytical methods developed for amino acid analysis were successfully applied to the analysis of modifications resulting from 2-oxoglutarate and Fe dependent oxygenase activity. Stereochemistry of lysyl hydroxylation in the splicing regulatory protein Luk7L2 by JmjD6 as well as of the self hydroxylation of the JmjD6 was identified. The stereochemistry was shown to be different from that of previously reported for the collagen hydroxyline, hydroxylated by the another member of this enzyme family. mbP4H enzyme was shown to catalyse prolyl hydroxylation of taODD resulting in 4R-hydroxyprolyl. Amino acid analysis was used in order to verify the mechanism of the hBBOX catalysed rearrangement of Mildronate. Using the method developed for the analysis of non-derivatised amino acids the screening of potential substrates of hBBOX enzyme was carried out and two new substrates were identified. The isotope ratio mass spectrometry protocol was applied to the study of histones from cell culture; low levels of hydroxylated and methylated amino acids were quantified. The analytical methods described were developed to complement to the well established proteomics techniques. The methods developed enable investigation into the region- and stereo- chemistry of the modified groups within the modified AA residue and has proved to be a powerful tool of exploratory PTM analysis.
35
Wiblin, Louise. "Quality of life and palliative care need in multiple system atrophy and progressive supranuclear palsy : a pilot study using quantitative and qualitative methods". Thesis, University of Newcastle upon Tyne, 2017. http://hdl.handle.net/10443/3939.
Abstract (sommario):
Background Multiple System Atrophy (MSA) and Progressive Supranuclear Palsy (PSP) are atypical Parkinsonian disorders which are rapidly progressive. The impact that Parkinsonian disorders has on quality of life (QoL) is increasingly understood, though less work has been done in MSA and PSP compared to Parkinson’s disease. The role of Palliative Care in enhancing QoL is beginning to be translated into clinical practice though fewer studies have been done in MSA and PSP compared with Parkinson’s disease. Methods A cross-sectional study of 23 MSA patients and 24 PSP patients was carried out, assessing aspects of QoL, depression, palliative symptoms and clinical milestones such as dysarthria. Carers for each disease type were assessed in terms of carer strain and QoL. A range of QoL measures including subjective, disease-specific and general QoL scores were taken with the aim of achieving a holistic impression of QoL and symptom burden. A subset of participants were selected for interviews to obtain personal perspectives of living with these conditions. The interviews were evaluated using thematic analysis, to gain a still fuller, richer picture of the implications of these diseases on QoL for patients and carers. The use of both quantitative and qualitative methods was intended to complement each other, with the recognition that QoL is a complex and subjective concept and cannot be encompassed using a single type of assessment. Results Using multiple linear regression, QoL was predicted for by depression and palliative need in MSA and PSP, with severity having an influence in PSP only. Carer mental well-being and patient depression influenced different aspects of carer QoL. Issues with legs was the highest-rated symptom in both groups and there was no significant difference in palliative need between MSA and PSP. Subjective QoL using the SEIQoL-DW score produced diverse domains which people felt influenced their QoL. The most commonly nominated were ‘family’ and ‘partner’; some domains in common were discussed in interviews. ii The overarching themes in interviews were connection to others, transitions (including adjustment) and seeking support, from peers, palliative care services and sourcing expertise for these rare conditions. Conclusion MSA and PSP have a profound effect on QoL, seen using a range of QoL scores. Depression and symptoms frequently managed in palliative care, predict for patient disease-specific QoL, though severity seems to have a greater impact on QoL in PSP compared with MSA. Carer QoL is impacted by patient depression and by carers’ own mental well-being. This work emphasises that QoL in progressive neurological disorders is heterogeneous and individual. Patients and their carers would likely benefit from an individualised, palliative approach supporting patients through the course of their disease, maximising QoL to enhance the experience of living with a progressive disease.
36
Frayer, Jens Verfasser], Manfred [Akademischer Betreuer] [Frühauf, D. [Akademischer Betreuer] Schmidt-Voigt e D. [Akademischer Betreuer] Müller. "Understanding forest-cover change in Yunnan with a combination of quantitative and qualitative methods / Jens Frayer ; Manfred Frühauf, D. Schmidt-Voigt, D. Müller". Halle, 2016. http://d-nb.info/1116952599/34.
37
Williams, Tywana. "A Qualitative Evaluation of Leader-to-Millennial Relationship Development". ScholarWorks, 2016. https://scholarworks.waldenu.edu/dissertations/2304.
Abstract (sommario):
Generational conflicts affect socialization practices needed for knowledge transfer and Millennial retention. Because of failed socialization practices, organizations will face significant losses in knowledge capital as Boomers retire and Millennials began to take active roles within the workplace. This interpretative phenomenological study explored Millennials' perceptions of leader-to-employee relationship development that may influence organizational learning and retention practices. Millennial retention is a primary concern in that knowledge acquired is a result of longevity and work experience. The leader-to-member exchange theory was used to navigate this qualitative inquiry. The reflexive approach was implemented to explore 20 Millennial participants' experiences with their managers. The data analysis strategy incorporated a repetitious review and structural coding of participant interview transcripts. Data analysis affirmed that Millennials perceive effective relationship development as a process containing leader empowerment behaviors with collaborative social exchanges. Exploration of participant experiences further identified that reciprocity is a result of high-quality social exchanges. Research findings benefit executive and middle-level management. The information broadens management knowledge of Millennials' perceptions of relationship development that may increase employee retention needed for robust social systems. The implications for positive social change are that increased awareness of advanced relational leadership systems assists in building congruent internal relationships required for organizational learning and retention.
38
Carrington, Linda. "A Qualitative Phenomenological Study of Employee Perceptions of the Impact of Layoffs". ScholarWorks, 2016. https://scholarworks.waldenu.edu/dissertations/2800.
Abstract (sommario):
Millions of Americans were terminated from their employment in massive layoffs in 2013, which not only created outrage among employees. but also opened the door for retaliatory lawsuits. However, profitable companies are still engaged in restructuring and layoffs, which have a negative effect on employees, managers, and survivors. Such actions create mistrust in management and continue to plague the workforce and the economy. The purpose of this phenomenological study was to explore the impacts that layoffs and downsizing have on employees' trust, work performance, behavior, and health. Informed by Sarker's theory on management and employee trust, the research questions explored participants' work attitudes and performances after layoffs had taken place. Twenty participants, both managers and workers who were laid off or who had survived layoffs, took part in semistructured interviews. The data were coded and analyzed using comparative analysis. The results showed (a) most employees do not trust management, (b) stress and low morale were the most common effects from layoffs, and (c) employee productivity was limited during and after the downsizing process. The study can contribute to positive social change by identifying ways for company leaders to manage impacts of layoffs and implement effective organizational communication strategies that may result in reduced stress for laid off employees and a more productive work environment for surviving employees and managers.
39
Humphrys, Elka Suzanne. "Understanding the pathways to oesophageal and stomach cancer diagnosis : a multi-methods approach". Thesis, University of Cambridge, 2019. https://www.repository.cam.ac.uk/handle/1810/289397.
Abstract (sommario):
Increasing symptom awareness, encouraging help-seeking, and facilitating timely referral are key for improving cancer outcomes, particularly for cancers such as oesophageal and gastric (stomach), where five-year survival is less than 20%. In this research, I used multiple methods to explore factors that influence timely diagnosis of these cancers from a patient's perspective, with a particular focus on health literacy (accessing, understanding and using health information, and navigating healthcare systems). I started by exploring current knowledge in this field before conducting a systematic review investigating health literacy in the timely diagnosis of symptomatic cancer. Literature was searched from January 1990-May 2017 using six bibliographic databases. I screened 2304 titles/abstracts, assessed 26 full-text papers and included three, although they were methodologically weak, therefore limiting the conclusions. To examine pathways to diagnosis for oesophageal and gastric cancer, I conducted a questionnaire study of newly diagnosed patients across two hospitals in the East and North East of England. 127 participants were recruited (39.6% recruitment rate), aged 44-96 (median 71); 102 male (80%). Most had oesophageal cancer (n=102, 80%); 64 (50%) of the total cohort were late-stage at diagnosis. Common pre-diagnostic symptoms varied between cancers (oesophageal: difficulty swallowing (n=66, 65%), painful swallowing (n=55, 54%); gastric: fatigue/tiredness (n=20, 80%), weight loss (n=13, 52%)). The questionnaire included two domains (engagement, understanding) of the Health Literacy Questionnaire with participants demonstrating high health literacy (mean 4.18 and 4.28, score 1-5). The median time from noticing the trigger symptom (prompting help-seeking) to diagnosis was 81 days (IQR 45-137.5, n=107). Twenty-six participants were purposively sampled, from questionnaire respondents, for face-to-face interviews (aged 55-88, 18 male, 15 with oesophageal cancer). I undertook thematic analysis to explore participant accounts of their pathways to diagnosis, identifying that the symptom nature was important for appraisal, while health literacy ability influenced the health system interval. Descriptions of 'heartburn', 'reflux' and 'indigestion' differed between participants, suggesting these terms may introduce uncertainty in relation to symptom experience. This is the first study to explore the role of health literacy in the timely diagnosis of symptomatic cancer, and pathways to diagnosis for oesophageal and gastric cancers, from a patient's perspective. Findings provide important insights for the development of targeted awareness campaigns and strategies enhancing GP symptom exploration.
40
Teeley, Aubriana M. "Knitting as an Adjunctive Treatment for Substance Use Disorder: A Mixed Methods Multiple Case Study". Antioch University / OhioLINK, 2018. http://rave.ohiolink.edu/etdc/view?acc_num=antioch1541530708768503.
41
Haddad, Hebba. "Dynamics of communicating climate change information : using mixed methods to examine the perspectives of scientists, communicators and publics". Thesis, University of Exeter, 2014. http://hdl.handle.net/10871/16883.
Abstract (sommario):
The communication of anthropogenic climate change presents many challenges, for communicators, scientists, policymakers and publics alike. Particularly difficult is the issue of uncertainty, which can include ambiguity around the phenomenon of climate change, the possible impacts of this, and the timeframe within which such impacts will be seen. Previous research has established that audiences are often averse to uncertainty, and will disregard or ignore messages that contain it. This raises a theoretical and practical question of how best to manage uncertainty in climate change communication in order to maintain audience engagement. This question was the focus of this PhD research. Specifically, the aim of this thesis was to explore the process of climate change communication from the perspectives of the scientists, communicators, and the recipient. I achieved this research goal by utilising a mixed methods design. I firstly interviewed the originators (i.e., scientists) and professional communicators of climate change information to explore the process from their side (Chapter 2). This revealed a number of themes connecting to the different ways scientists and communicators understand the process of communication (e.g., as information exchange versus relationship building), the challenges of climate change communication and uncertainty in particular, and the (appropriate) role of scientists when communicating with the public about climate change. Next, in a series of studies I experimentally explored how audiences respond to variations in the informational content of climate change messages (such as the level of uncertainty) and the role of different communicative styles in further shaping audience engagement (Chapter 3). Broadly, the results of these studies suggest that while uncertainty can undermine audience engagement with climate change communications, the negative effects of uncertainty are buffered when the communicator is perceived to be high in morality and/ or when they use an open communication style. Interestingly, these effects of communication style were particularly evident among women, whereas men tended to react against this. Together, these studies show how relational factors (e.g., communication styles and perceptions of communication sources) can moderate the impact of informational content on audience responses. Finally, I ended this programme of research by looking in more detail at how audiences perceive a real scientific organisation engaged in climate change communication and the bases of their beliefs about organisation competence and morality (Chapter 4). This study combined qualitative and quantitative data to delve deeper into some of the insights gained in the experimental work, and to reconnect this to the real-world organisation context I began with. This study again showed how perceptions of communicator morality moderate responses to uncertainty, but also provide useful insights into the different origins of perceptions of morality and competence. Chapter 5 concludes by summarising the research presented in this thesis, discussing its strengths, limitations and ways forward. Here, I also consider the theoretical, methodological and practical implications of the thesis’ research findings. Briefly, it is argued that addressing the scientific uncertainties of climate change may not necessarily mean altering the form of information itself. Rather, modifying the language peripheral to the information that contains uncertainty, attending to the ways in which audiences perceive the sources of uncertainty, and considering variations amongst publics, may help to engage in effective communication around the complex issue of climate change.
42
Jones, Willie Brad. "Exploring a combined quantitative and qualitative research approach in developing a culturally competent dietary behavior assessment instrument". Diss., Atlanta, Ga. : Georgia Institute of Technology, 2009. http://hdl.handle.net/1853/29718.
Abstract (sommario):
Thesis (Ph.D)--Industrial and Systems Engineering, Georgia Institute of Technology, 2009.Committee Chair: Vidakovic, Branislav; Committee Member: Edwards, Paula; Committee Member: Griffin, Paul; Committee Member: Grinter, Rebecca; Committee Member: Mullis, Rebecca. Part of the SMARTech Electronic Thesis and Dissertation Collection.
43
Felder, Charmaine. "The Potential Role of Business Intelligence in Church Organizations". ScholarWorks, 2011. https://scholarworks.waldenu.edu/dissertations/1030.
Abstract (sommario):
Business intelligence (BI) involves transforming data into actionable information to make better business decisions that may help improve operations. Although businesses have experienced success with BI, how leaders of church organizations might be able to exploit the advantages of BI in church organizations remains largely unexplored. The purpose of the phenomenological study was to explore the perceptions of pastoral leaders concerning the potential usefulness of BI in church organizations. Conceptual support for the study was based on the premise that churches may also benefit from BI that helps improve decision making and organizational performance. Three research questions were used to examine the current role of BI in church organizations, the potential usefulness of BI in church organizations, and potential conflicts that might exist between spiritual and BI management objectives. Semistructured interviews were used to obtain data from 20 pastoral leaders. The data were analyzed using the modified Van Kaam method of analysis. The results indicated that pastoral leaders perceived that BI can be a useful technology in church organizations. Additionally, the pastoral leaders did not perceive any conflict between BI and church management objectives. Church leaders may be able to take advantage of BI to achieve their social outreach programs. As a result, local churches can have a greater social impact on the surrounding communities.
44
Thompson-Elliott, Racquel. "A Qualitative Study of the Growth Strategies of Mature Small Businesses". ScholarWorks, 2016. https://scholarworks.waldenu.edu/dissertations/3009.
Abstract (sommario):
Some small businesses have slower growth as they age and have limited strategies to maximize profit, productivity, and job creation. The purpose of this qualitative study was to explore the strategies small business managers use to capitalize on growth opportunities. Area small business managers and support program stakeholders could gain new knowledge to develop effective support for mature small businesses. Twenty managers participated in this case study. These managers were from small businesses operating in the state of Florida for more than 5 years with less than 500 employees. The data collection approach included purposeful sampling and semistructured interviews with open-ended questions. In addition, literature on small business growth of policies and procedures was reviewed. The general systems theory conceptual framework was the guide for this study. The thematic approach was used to have the data analyzed using word frequency, text search, and coding. The themes emerging from this study were growth decisions and internal environment, growth decisions and external environment, using alternative growth strategies, heterogeneous growth strategy processes, consulting, researching, and planning growth, accessing support for growth strategies, and overcoming challenges with success attributes. These findings could assist area professional practitioners learn more about the decision making process used by small business managers including the indicators used to measure growth and identify growth opportunities. The findings could also contribute to continued job creation and economic growth of the local community.
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Воронцова, Анна Сергіївна, Анна Сергеевна Воронцова e Anna Serhiivna Vorontsova. "Розробка методики оцінки аудиторського ризику ТОВ «Сумитеплоенерго»". Thesis, Українська академія банківської справи Національного банку України, 2014. http://essuir.sumdu.edu.ua/handle/123456789/60003.
Abstract (sommario):
У роботі досліджуються сутність аудиторського ризику та основні методи його оцінки - кількісні і якісні. Також, представлено власну методику оцінки аудиторського ризику у розрізі окремих його складових на прикладі досліджуваного підприємстваТОВ «Сумитеплоенерго».The paper examines the definition of audit risk and it's basic methods of evaluation - quantitative and qualitative. Also it was presented own method of assessment of audit risk in terms of its individual components on the example investigated by LLC "Sumyteploenerho."
46
Holste, Angela Sarah [Verfasser]. "Development of bio-analytical methods for the quantitative and qualitative analysis of labelled peptides and proteins via hyphenation of chromatography and mass spectrometry / Angela Sarah Holste". Kiel : Universitätsbibliothek Kiel, 2014. http://d-nb.info/1053326149/34.
47
Makiya, George Kidakwa. "A Multi-Level Investigation into the Antecedents of Enterprise Architecture (EA) Assimilation in the U.S. Federal Government: A Longitudinal Mixed Methods Research Study". Case Western Reserve University School of Graduate Studies / OhioLINK, 2012. http://rave.ohiolink.edu/etdc/view?acc_num=case1338942189.
48
Reisdorf, Bianca C. "Internet non-use : a comparative study of Great Britain and Sweden". Thesis, University of Oxford, 2013. http://ora.ox.ac.uk/objects/uuid:c5bf2d53-986f-438d-8254-c03888900738.
Abstract (sommario):
Digital inequalities continue to concern researchers across highly technologised countries. In recent years, however, most research on digital inequalities has focused on distinguishing different patterns of Internet use rather than examining Internet non-users. The few quantitative studies of non-use and reasons for non-use often stay on a descriptive level, while qualitative studies mostly investigate subpopulations, such as those living in specific neighbourhoods. Although there are a number of studies of digital inequalities among young people and the elderly, a systematic literature search finds no research focusing on middle-aged individuals, who might face specific problems with being offline, as they are of working age and more likely than other age groups to have children living in the household. On the basis of a mixed-methods research design that compares non-users in Great Britain and Sweden, the overarching research question for this study sheds light on the mechanisms contributing to Internet non-use, as it examines the socio-economic backgrounds, attitudes, perceptions, and everyday life experiences of non-users with a focus on 25 to 55 year-olds. It applies advanced statistical analyses of secondary nationally representative survey data as well as in-depth analysis of qualitative interviews with 10 middle-aged non-users from each country. The analysis of these combined data shows that while socio-economic variables still play an important role in influencing who is on- and offline, general attitudes towards technologies are even more influential. The study finds that there is a lack of life-fit (Selwyn 2006) of ICTs for a number of non-users and a potentially negative impact of warm experts (Bakardjeva 2005) who have previously been regarded as a positive influence. Moreover, vulnerable groups (e.g. immigrants) are facing more substantial problems, such as issues with literacy and language, which need to be tackled first. The deliberation of similarities and differences between Britain and Sweden against the backdrop of policy interventions and cultural values shows that being offline is not problematic for all Internet non-users; some of them thrive in highly technologised societies. The conclusion offers proposals for both future research and policy interventions for those, currently offline mainly due to socio-economic reasons, who would like to go online in the future.
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Бреус, Світлана Василівна, e Євгеній Олегович Семченко. "Методи прийняття управлінських рішень". Thesis, ДВНЗ "Переяслав-Хмельницький державний педагогічний університет імені Григорія Сковороди", 2018. https://er.knutd.edu.ua/handle/123456789/10541.
Abstract (sommario):
Здійснене дослідження теоретико-методичних аспектів прийняття управлінських рішень в умовах ризику та невизначеності. Розглянуто основні методи прийняття управлінських рішень.Investigation of the theoretical and methodological aspects of making managerial decisions in terms of risk and uncertainty has been substantiated. The main methods of making managerial decisions has been considered.
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Annikova, Elena. "Public Service Announcement: the way to attract attention to problem in society and to change model of social behavior : a multi methods research, which is combined both of quantitative and qualitative methods, about Public Service Announcement". Thesis, Högskolan i Gävle, Akademin för hälsa och arbetsliv, 2011. http://urn.kb.se/resolve?urn=urn:nbn:se:hig:diva-12310.
Abstract (sommario):
This multi methods research, which is combined both of quantitative and qualitative methods, is about Public Service Announcement (PSA). This study is aimed to find out if something changes in behavior of people and their attitude to social problem in Russia by an impact of PSA and to understand whereby PSA impacts on changes in behavior of people and rise of attention to social problem in Russia. In order to achieve thesis aims, various types of data presented in this research: a survey of 50 people from different age and sex groups and interviews with a workers of two social organizations. To analyze a data, it were used a univariate and bivariate analysis for quantitative data. Analysis of qualitative data is done in a phenomenological way. According to the results, PSA performs its tasks, something it’s changed in people by impact of PSA, people of all ages noted an influence of PSA on them, they get to know about social problem, begin to think about or changed their behavior, begun to work as volunteers, made a donation. By all this aspects as emotion, feeling, sensation, design, PSA impact on changes in behavior of people and rise of attention to social problem in Russia. PSA impacts across effective psychological mechanism such as an emotional sphere of personality. Psychological aspects can be divided into cognitive and emotional. Emotion is one of the key factors of the PSAs. It is established that emotional memory is much stronger than other types of memory, affects human behavior. Cognitive component is related to how advertising information is perceived by people. All elements like an illustration, title, text, logo, layout and general features of the image determine the overall effect of advertising. PSA is a display of goodwill of society, its principled position on socially significant values. Social advertising can and should be considered as a mode of operation of social services.