Tesi sul tema "Antimicrobial propertie"
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Prats, Ejarque Guillem. "Exploring the pharmacological properties of human antimicrobial ribonucleases". Doctoral thesis, Universitat Autònoma de Barcelona, 2021. http://hdl.handle.net/10803/671628.
Esta tesis se enfoca en la caracterización estructural y funcional de las propiedades biológicas de las RNasas antimicrobianas de la superfamilia de la RNasa A. Concretamente, se han alcanzado los siguientes objetivos en el corto plazo: La caracterización estructural y funcional de la RNasa 6 por cristalografía de rayos X, dinámica molecular, mutagénesis dirigida y análisis enzimáticos destaca el papel clave de las regiones remotas de unión al sustrato. A parte, hemos identificado un posible segundo centro activo en la RNasa 6. Finalmente, un estudio evolutivo de los distintos miembros de la superfamilia de la RNasa A ha revelado una tendencia clara, a lo largo de la evolución en vertebrados, desde la preferencia de la guanina hacia adenina en la arquitectura de la región secundaria de unión a bases B2. A lo largo del trabajo experimental realizado en esta tesis, hemos buscado la caracterización del mecanismo de acción bactericida de las RNasas, una de las principales líneas de investigación de nuestro grupo de investigación. En este trabajo, nos hemos enfocado específicamente en la optimización del péptido derivado del N-terminal de la RNasa 3, ECP(5-17P24-36), y en el diseño de una RNasa quimérica antimicrobiana (RNasa 3/1). Respecto al péptido ECP(5-17P24-36), se ha optimizado mediante varias metodologías, llegando a la conclusión que el mejor candidato antimicrobiano es su enantiómero total D-ECP(5-17P24-36). Por lo que respecta a la RNasa 3/1, esta incorpora las características estructurales de las RNasas 1 y 3, combinando así su elevada actividad catalítica y bactericida, respectivamente. Se diseñó un primer constructo con éxito, pese a que no presentaba los mismos niveles de actividad bactericida que la RNasa 3. Entonces, diseñamos dos nuevas versiones de la RNasa 3/1 que incorporaban el loop C-terminal de la RNasa 3, en el que se identificó un motivo estructural específico asociado al reclutamiento del autofagosoma. Es interesante destacar la capacidad de la primera versión de la quimera RNasa 3/1 de retrasar la adquisición de resistencia a la colistina en un ensayo evolutivo in vitro de exposición a la colistina en cultivos de Acinetobacter baumannii. En global, estos resultados ayudarán a elucidar el modo de unión al RNA de las ribonucleasas y su mecanismo antimicrobiano, así como su contribución en el sistema inmunitario innato, con prometedoras aplicaciones farmacológicas.
This thesis project focuses on the structural-functional characterization of the biological properties of antimicrobial RNases from the RNase A superfamily. Specifically, the following short-term goals have been achieved: Structural and functional characterization of RNase 6 by X-ray crystallography, molecular dynamics, site-directed mutagenesis and enzymatic analysis have highlighted the key role of remote binding subsites. Besides, we have identified in RNase 6 a putative novel secondary active site. In addition, an evolutionary study of several members of the RNase A superfamily have revealed a clear drift from guanine to adenine preference at the secondary base binding site (B2) architecture along vertebrate evolution. During this thesis’ experimental work, we have pursued the characterization of RNases’ bactericidal mechanism of action, a long-term object of study in our research group. Here, we have specifically focused on the optimisation of the antimicrobial peptide derived from RNase 3, ECP(5-17P24-36), and the design of a chimeric antimicrobial RNase (RNase 3/1). Regarding the N-terminus peptide ECP(5-17P24-36), it has been optimised by several methodologies. We have concluded the best antimicrobial candidate to be its total enantiomer, D-ECP(5-17P24-36). As for RNase 3/1, this chimera encompasses structural features from RNases 1 and 3 parental proteins to combine both high catalytic and bactericidal activities. A first construct was successfully achieved, albeit not reaching the bactericidal activity levels of RNase 3. Therefore, we designed two more versions of RNase 3/1 that incorporate the RNase 3 C-terminus loop. A specific tag motif was identified in that region associated to autophagosome recruitment. Interestingly, the hybrid chimera RNase 3/1 was able to delay the acquisition of bacterial resistance to colistin using an in vitro evolutionary exposure assay in Acinetobacter baumannii cultures. Overall, the results shed light on the elucidation of substrate binding architecture and antimicrobial mechanism of action of RNases and their contribution to the innate immune system, with promising pharmacological applications.
Universitat Autònoma de Barcelona. Programa de Doctorat en Bioquímica, Biologia Molecular i Biomedicina
Cai, Zhiwei. "Nouveaux matériaux à base de polyoxotitanates (POTs) dopé ou à base de complexe salicylate de titane (IV) et d'argent (I)". Electronic Thesis or Diss., Strasbourg, 2023. http://www.theses.fr/2023STRAF062.
In recent years, titanium dioxide has attracted much attention as a highly stable material with a wide range of applications from white pigment to its applications as a semiconductor or advanced photonic devices. Using recently developed synthetic approaches, the synthesis of atomically well-defined polyoxotitanate (POT, [TixOy(OR)z]) cage molecules can be determined. POTs may be preferred as soluble models of TiO2. Cages doped with a metal M (M-POT) presenting new properties can also be prepared.Two new cages doped with cerium were synthesized by a solvothermal reaction. The cages [Ti28O38(OEt)38CeCl](EtOH)1.4 and [Ti8O7(OEt)21Ce](EtOH) having different solubilities, they will be able to be separated and characterized by 1H NMR and X-ray diffraction. The Fe-doped POTs: [Ti4(OEt)15O(FeCl)] and [FeTi14(OEt)28O14(OH)2] were also synthesized. Then after hydrolysis with or without calcination, materials based on Ce or Fe and TiO2 can be obtained. Emulsions of its materials and with the cerium-doped PVDC polymer were then deposited on a PVC surface. UV absorption and water barrier performance gradually increases with increasing amount of deposited materials. The results are interesting for the use of these materials on the packaging surface of drug tablets, which will increase their expiry date. The Eu-POT cage doped with the Eu(III): Ti2O(OEt)8EuIIICl(EtOH)]2 was also synthesized, then after hydrolysis and calcination, the photoluminescence properties of the obtained material were studied.Finally, an AgITiIV(SC)2(HSC)(CH3CN) complex (SC2- = salicylate) was prepared. After hydrolysis and calcination, the anti-microbial properties of the materials were successfully tested against S. aureus or E. Colis
Cinar, Dursun. "Purification and antimicrobial properties of oleuropein". Thesis, University of West London, 2009. https://repository.uwl.ac.uk/id/eprint/381/.
Nilebäck, Linnea. "Recombinant spider silk with antimicrobial properties". Thesis, Linköpings universitet, Institutionen för fysik, kemi och biologi, 2013. http://urn.kb.se/resolve?urn=urn:nbn:se:liu:diva-102804.
Bortolin, M. "ANTIMICROBIAL PROPERTIES OF PLATELET-RICH PLASMA". Doctoral thesis, Università degli Studi di Milano, 2014. http://hdl.handle.net/2434/233150.
Khadambi, Tshiwela Norah. "Antimicrobial properties of phenolic compounds from sorghum". Pretoria : [s.n.], 2005. http://upetd.up.ac.za/thesis/available/etd-03022007-164705.
Parr, J. A. "Antimicrobial properties of silicone quaternary ammonium compounds". Thesis, Bucks New University, 1986. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.375600.
Liu, Harris K. (Harris Ken-Ming). "New immobilized antimicrobial polyethylenimines : synthesis and properties". Thesis, Massachusetts Institute of Technology, 2014. http://hdl.handle.net/1721.1/93039.
Cataloged from PDF version of thesis.
Includes bibliographical references.
Surfaces modified with immobilized N-alkyl-polyethylenimines (N-alkyl-PEls) containing various alkyl groups were synthesized and tested against various pathogenic human influenza viruses to establish structure-to-virucidal activity relationships. Various physical-chemical properties of each surface were correlated with their virucidal activities to identify key antiviral surface properties. The accessibility of N-alkyl-PEI quaternary ammonium groups to influenza virus was subsequently identified as the key determinant of antiviral efficacy, as demonstrated by FITC-lysozyme surface titration. Previously used multistep syntheses to create antimicrobial surfaces by immobilizing Nalkyl- PEls were replaced with a novel aerosol-assisted plasma deposition procedure. N,N-hexyl,methyl-polyethylenimines were directly plasma-coated onto a glass surface. The resulting material was thoroughly characterized and demonstrated to be robust, scalable, bactericidal against Escherichia cofi, and virucidal against human influenza virus. Biocompatibility and bactericidal properties of N-alkyl-PEls immobilized on Boston Keratoprosthetic implants were evaluated in vivo. Surface-attached N,N-hexyl,methylpolyethylenimines exhibited inhibitory effects on Staphylococcus aureus biofilm formation, with no toxicity or adverse reactivity detected.
by Harris K. Liu.
S.M.
Sharma, Shagun. "Investigation of Antimicrobial Properties of Spider Silk". University of Akron / OhioLINK, 2014. http://rave.ohiolink.edu/etdc/view?acc_num=akron1418647204.
Desai, Prerak T. "Antimicrobial Properties of Syringopeptin 25A and Rhamnolipids". DigitalCommons@USU, 2006. https://digitalcommons.usu.edu/etd/5526.
Mwangi, Henry Maina. "Phytochemical and antimicrobial studies on Rhus natalensis". Thesis, University of the Western Cape, 2011. http://etd.uwc.ac.za/index.php?module=etd&action=viewtitle&id=gen8Srv25Nme4_3552_1365671232.
Extracts from the root bark, stem bark, and leaves of R. natalensis were screened for antibacterial activity against standard bacterial strains
Staphylococcus aureas, Escherichia coli and Pseudomonas aureginosa, and fungi
Candida albicans, Trichophyton mentagrophytes or Microsporum gyseum. Chromatographic techniques were utilized to isolate pure compounds. This study validates and documents, in a systematic way, the antimicrobial properties of the R. natalensis used for many years by many people of the world. It also provides valuable information for 
further phytochemical isolation and characterization studies of active compounds, necessary for the development of new drugs. The extractions were carried out using broad spectrum of solvents 
(hexane, dichloromethane, ethyl acetate, and methanol). Fractionation was done using standard chromatographic techniques. A total of seven (7) compounds were isolated from R. natalensis. 
Three of the isolates were characterized and their structures were unambiguously established by detailed spectroscopic analysis that involved high resolution mass spectrometry, 1D and 
2D-NMR spectral data experiments 1H, 13C, DEPT, COSY, HMBC, and NOESY. These compounds are: 3-(1-(2,4-dihydroxyphenyl)-3,3-bis(4- hydroxyphenyl)-1-oxopropan-2-yl)-7-methoxy- 4H-chromone-4-one (39), Rhuschromone, a 
novel compound isolated for the first time, 2&rsquo
,4&rsquo
-dihydroxychalcone-(4-O-5&rsquo
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- trihydroxychalcone (40) and 3-((Z)-heptadec-13-enyl) benzene- 1,2-diol (41), an urushiol. Compound 39 recorded the highest activity zone of inhibition (21mm) against S. aureas, which was found to be 50% as active the chloramphenicol standard used. The 
traditional use of the extracts in infections and inflammatory conditions is rationalized based on the content of theisolated compounds, and it has been proposed that the total crude extract, with its 
contents of so many bioactive compounds, could be formulated for use in many infections, microbial or fungal. Furthermore, not all of the species studied to date have been fully characterized 
for potential bioactivities. Thus, there remains a significant research gap spanning the range from lead chemical discovery through process development and optimization in order to better 
understand the full bioactive potential of many of these plants.
Gule, Nonjabulo Prudence. "Electrospun antimicrobial and antibiofouling nanofibres". Thesis, Stellenbosch : Stellenbosch University, 2011. http://hdl.handle.net/10019.1/18057.
ENGLISH ABSTRACT: The main objective of this study was to develop electrospun nanofibres with both antimicrobial and antibiofouling properties for possible application in water filtration. To do this, two routes were investigated: firstly, the use of biocides and bactericidal copper salts to introduce bactericidal properties on electrospun nanofibres. Secondly, the modification of polymers using furanone compounds to obtain nanofibres with the ability to repel microbial attachment. Fabrication of biocide-containing PVA nanofibres was successful. This was achieved through direct doping of PVA solutions with AquaQure which is an aqueous biocide comprising of mainly Cu2+ and Zn2+, prior to the electrospinning process coupled with chemical crosslinking using glyoxal. The conventional needle based electrospinning technique was used to fabricate these nanofibrous mats. The presence of the constituents of AquaQure on surfaces of PVA/AquaQure nanofibrous mats was confirmed using energy dispersive x-ray analysis (EDX). ATR/FTIR, XRD, TGA, DSC and SEM techniques were used to do chemical and thermal analysis of the nanofibres in comparison with pristine PVA nanofibres. These nanofibres demonstrated antimicrobial activity of up to 5 log against the Gram-positive strain S. aureus Xen 36 and Gram-negative strains E. coli Xen 14, S. typhimurium Xen 26, P. aeruginosa Xen 5 and K. pneumoniae Xen 39. Because of crosslinking, these fibres also demonstrated good water stability. Leaching of the ions constituting AquaQure was limited and compared with South African national standards for drinking water, the water filtered through these nanofibress was deemed safe for human consumption. Bioluminescence imaging and fluorescence microscopy were used to confirm antimicrobial activity results obtained from plate counting. These nanofibres demonstrated satisfactory antimicrobial efficiency but did not repel microbial attachment. The second part of this study entailed the investigation of copper-doped PVA and SMA nanofibres for antimicrobial activity. Although bactericidal properties of copper are well documented, its selection was based on the fact that it is the main constituent of the AquaQure. Bubble electrospinning was used instead of needle electrospinning to upscale nanofibre production. Similar techniques as those used in PVA/AquaQure nanofibres were used to characterize the copper functionalized nanofibres. Even though these nanofibres demonstrated exceptional antimicrobial efficacy (up to 5 log) for all the strains, bioluminescence imaging indicated a trend for these cells to enter a dormant state on contact with the copper containing-nanofibres. The last part of this project involved testing of free furanone compounds as well as surface-tethered furanone-modified nanofibres for their antibiofouling potentials. To do this, blends of 2,5-dimethyl-4-hydroxy-3(2H)furanone (DMHF) (5% wt/vol) with PVA (10% wt/vol) were prepared and electrospun to produce PVA/DMHF nanofibres. The free furanones and furanone-modified nanofibres demonstrated not only antibiofouling properties but also antimicrobial activity. Other furanone compounds with 3(2H) and 2(5H) cores were synthesized. The synthesis of these furanone compounds (5-(2-(2-aminoethoxy)ethoxy)methyl)-2(5H)furanone and 4-(2-(2-aminoethoxy)-2,5-dimethyl-3(2H)-furanone) was successful. Their structures and molar masses were confirmed using 1H NMR and ES mass spectroscopy. These furanones were then covalently immobilized on the SMA backbone. To test their antimicrobial and antibiofouling activity, the furanone-modified polymer was dissolved in an ethanol and methanol mixture (1:1) and electrospun to produce nanofibres. The free furanone and furanone-modified SMA nanofibres derived from 4-(2-(2-aminoethoxy)-2,5-dimethyl-3(2H)-furanone demonstrated high antibiofouling and antimicrobial efficiency against the Gram-positive strain S. aureus Xen 36 and Gram-negative strains E. coli Xen 14, S. typhimurium Xen 26, P. aeruginosa Xen 5 and K. pneumoniae Xen 39. The 2(5H) furanone on the other hand had limited activity against the strains. These nanofibres were also characterized and compared with their pristine polymer counterparts and leaching experiments were conducted using GC-MS.
AFRIKAANSE OPSOMMING: Die hoofdoel van hierdie studie was om nanovesel filtrasie nanofibre met beide antimikrobiese en aanpakwerende eienskappe te ontwikkel. Twee verskillende metodes is ondersoek. Eerstens is biosiede en bakteriee-dodende koper soute gebruik om antimikrobiese nanovesels te lewer. Tweedens is nanovesels met furanoon samestellings gemodifiseer om nanovesels te lewer wat mikrobiese aanhegting voorkom. Die fabrisering van biosied-bevattende PVA nanovesel nanofibre was suksesvol. AquaQure, ‟n biosied wat hoofsaaklik uit Cu2+ en Zn2+ bestaan, is direk by PVA oplossings gevoeg voor die elektrospin proses, en is gevolg deur chemiese kruisbinding deur middel van “glyoxal”. Die nanovesels is neergele in ‟n ongeweefde mat deur middel van die konvensionele naald-gebasseerde elektrospin proses. Verspreidings X-staal analises (EDX) is gebruik om die teenwoordigheid van AquaQure komponente in en op die oppervlakte van die PVA/aquaqure nanovesel matte te bevestig. ATR/FTIR, UV-Vis, XRD, TGA, DSC en SEM tegnieke is gebruik vir chemiese en termiese analises om sodoende PVA/aquacure nanovesels met ongemodifiseerde PVA nanovesels te vergelyk. PVA/aquacure nanovesels het ‟n antimikrobiese aktiwiteit van tot 5 log reduksie getoon teen Gram-positiewe S. aureus Xen 36 en Gram-negatiewe E. coli Xen 14, S. typhimurium Xen 26, P. aeruginosa Xen 5 en K. pneumoniae Xen 39. Die vesels was stabiel in water na kruisbinding. Slegs beperkte uitloging van Aquaqure Cu2+ en Zn2+ ione is waargeneem, en water wat deur die PVA/aquacure nanovesels gefiltreer is, is volgens Suid Afrikaanse Nasionale Standaarde vir drinkwater steeds veilig vir menslike gebruik. Behalwe vir die plaat-tellingsmetode het bio-lumiserende fotos en fluoroserende mikroskopie ook die antimikrobiese aktiwiteit van die vesels bevestig. Die vesels het bevredigende antimikrobiese efektiwiteit getoon, maar kon nie mikrobiese aanhegting voorkom nie. In die tweede gedeelte van die werk is die antimikrobiese aktiwiteit van PVA en SMA vesels wat met koper verreik is, ondersoek. Alhoewel die bakteriee dodende eienskappe van koper reeds goed gedokumenteer is, is hierdie ondersoek gedoen op grond van die feit dat koper een van die hoof komponente van aquaqure is. Nanovesels is uit koper-verreikte oplossings van PVA en SMA deur middel van die borrel-gebasseerde elektrospin tegniek gefabriseer, ten einde die opbrengs van nanovesels te verhoog. Fisiese kruisbinding deur middel van hitte behandeling is toegepas ten einde die stabiliteit van die vesels in water te verbeter. Dieselfde karakteriseringstegnieke wat gebruik is vir die PVA/aquacure vesels is op hierdie vesels toegepas. Alhoewel die vesels uitstekende antimikrobiese aktiwiteit van tot 5 log reduksie gedemonstreer het, het bio-lumiserende beeldvorming getoon dat die selle ‟n dormante stadium binnegaan na kontak met hierdie vesels. In die laaste gedeelte van die projek is vrye furanoon samestellings en nanofibre met oppervlak-gehegde furanone getoets vir aanpakwerende potensiaal. Om dit te bewerkstellig was „n mengsel van 2,5 – dimethyl-4-hydroxy-3(2H) furanone (DMHF) (5% wt/vol) en PVA (10% wt/vol) voorberei en gebruik om PVA/DMHF nanovesel filtrasie nanofibre te produseer deur middel van die elektrospin proses. Die vrye furanone en furanoon-gemodifiseerde nanofibre het nie alleen aanpak weerstandbiedende einskappe gedemonstreer nie maar ook antimikrobiese eienskappe. DMHF was gebruik as die begin material om furanoon samestellings te produseer met 3(2H) en 2(5H) kerne. Die sintesis van hierdie furanone se samestellings (5-(2-(2-aminoethoxy)ethoxy)methyl)-2(5H)furanone en 4-(2-(2-aminoethoxy)-2,5-dimethyl-3(2H)-furanone) was suksesvol. Hulle strukture en molere massas was bevestig met 1H NMR en ES massa spektrometrie. Hierdie furanone is daarna kovalent ge-immobiliseer op die SMA rugbeen. Om hulle antimikrobiese en aanpakwerende aktiwitiet te toets, is die furanoon-gemodifiseerde polimeer opgelos in „n etanol en metanol mengsel (1:1) en ge-elektrospin om nanovesel filtrasie nanofibre te produseer. Die furanone en furanoon-gemodifiseerde nanovesel filtrasie nanofibre afkomstig van 4-(2-(2-aminoethoxy)-2,5-dimethyl-3(2H)-furanone het hoe aanpakwerende en antimibrobiese effektiewitiet getoon teenoor die Gram-positiewe S. aureus Xen 36 en Gram-negatiewe E. coli Xen 14, S. typhimurium Xen 26, P. aeruginosa Xen 5 and K. pneumoniae Xen 39. Hierdie nanovesel filstrasie nanofibre is ook gekarakteriseer en vergelyk met die ongemodifiseerde polimeer. „n Uitlogings eksperiment is uitgevoer deur gebruik te maak van GC-MS.
Rodrigues, Maria do Livramento Linhares. "Tilapia skin Gelatin: Alternative for obtaining films with antimicrobial property by nanosilver incorporation". Universidade Federal do CearÃ, 2015. http://www.teses.ufc.br/tde_busca/arquivo.php?codArquivo=14546.
An alternative for the recovery of industrial fish waste is the production of films, which can be applied in food packaging. However, a major challenge is to obtain films with antimicrobial properties aiding in increased food shelf life as well as films with good mechanical properties and barriers. Therefore, in order to improve these limitations, silver nanoparticles were used due to its potential antimicrobial in food, and tannic acid (TA) as crosslinker in order to improve the mechanical and barrier properties. This study focuses in the extraction of gelatin from the Nile tilapia skin (Oreochromisniloticus) in order to produce gelatin films with embedded nanosilver (AgNPs) generated by green process and evaluate the addition of tannic acid (TA) in synthesis of AgNPs and mechanical properties of the films and barrier. A pre-treatment was conducted to obtain gelatin followed by a collagen denaturing. The characterization was done by gel strength, isoelectric point, electrophoretic analysis, fourier transform infrared (FTIR) and thermogravimetric analysis (TGA). The incorporation was performed by in situ method, the films were obtained with and without the presence of TA and AgNO3 concentrations were 0, 45, 90 and 180 mmol.L-1.The films were characterized by UV-Vis, FTIR, TGA, Mechanical properties (tensile strength and elongation at break), water vapor permeability (WVP), scanning electron microscopy (SEM) and antimicrobial analysis. It was possible to use gelatin as a reducing agent and stabilizer in the reduction of silver nanoparticles. Films produced with the addition of AT showed more suitable properties for the usage as packaging material for food, showing better WVP, water solubility and were more resistant to applied loads. In addition, they presented better antimicrobial activity. Therefore, it was possible to obtain the green AgNPs method through the incorporationof thegelatin matrix and to obtain films with excellent properties after the TA addition.
Uma alternativa de valorizaÃÃo de resÃduo de pescado produzidos por indÃstrias à a produÃÃo de filmes, que pode ser aplicados em embalagens para alimentos. PorÃm, um dos grandes desafios à obter filmes com propriedades antimicrobianas, auxiliando no aumento da vida de prateleira dos alimentos, bem como obter filmes com boas propriedades mecÃnicas e de barreiras. Para isso, a fim de melhorar essas limitaÃÃes, nanopartÃculas de prata foram utilizadas devido a sua potencial aÃÃo antimicrobiana em alimentos, e Ãcido tÃnico (AT) como agente reticulante a fim de melhorar as propriedades mecÃnicas e de barreiras. Nesse estudo objetivou-se fazer a extraÃÃo da gelatina a partir de pele de tilÃpia do Nilo (Oreochromis niloticus), visando a produÃÃo de filmes de gelatina incorporados com nanopartÃculas de prata (NPAg) geradas por processo verde e avaliar a adiÃÃo de Ãcido tÃnico (AT) na sÃntese das NPAg e nas propriedades mecÃnicas e de barreira dos filmes. Para a obtenÃÃo da gelatina foram feitos prÃ-tratamentos e em seguida a desnaturaÃÃo do colÃgeno. A caracterizaÃÃo foi feita por ForÃa de Gel, Ponto IsoelÃtrico, DistribuiÃÃo de Massa Molar, Espectroscopia no Infravermelho pro Transformada de Fourrier (FTIR) e AnÃlise TermogravimÃtrica (TGA). A incorporaÃÃo foi feita pelo mÃtodo in situ, Os filmes foram obtidos sem e com a presenÃa de AT e as concentraÃÃes de AgNO3 foram 0, 45, 90 e 180 mmol.L-1. Os filmes foram caracterizados por: UV-Vis, FTIR, TGA, Ensaios MecÃnicos, Permeabilidade ao Vapor de Ãgua (PVA), Microscopia EletrÃnica de Varredura (MEV) e AnÃlise Antimicrobiana. Foi possÃvel utilizar a gelatina como agente redutor e estabilizante na reduÃÃo de nanopartÃculas de prata. Os filmes produzidos com a adiÃÃo de AT apresentaram propriedades mais adequadas para uso como embalagem para alimentos, apresentando melhores PVA, solubilidade em Ãgua e mostraram-se mais resistentes a esforÃos aplicados. AlÃm de apresentarem melhor atividade antimicrobiana. Logo, foi possÃvel, obter pelo mÃtodo verde a incorporaÃÃo de NPAg na matriz de gelatina, alÃm, de se obter filmes com excelentes propriedades apÃs a adiÃÃo de AT.
Page, Kristopher. "Photocatalytic thin films : their characterisation and antimicrobial properties". Thesis, University College London (University of London), 2009. http://discovery.ucl.ac.uk/17547/.
Wallock-Richards, Daynea Juaneckah. "Natural products : biosynthesis, antimicrobial properties and protein targets". Thesis, University of Edinburgh, 2015. http://hdl.handle.net/1842/14188.
Oriani, Vivian Boesso 1986. "Desenvolvimento e caracterização de coberturas comestíveis à base de fécula de mandioca adicionadas de óleos essenciais". [s.n.], 2013. http://repositorio.unicamp.br/jspui/handle/REPOSIP/255153.
Dissertação (mestrado) - Universidade Estadual de Campinas, Faculdade de Engenharia de Alimentos
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Resumo: Coberturas comestíveis foram desenvolvidas e caracterizadas pela combinação de fécula de mandioca (2 e 3% p/v) com óleos essenciais de casca de canela (Cinnamomum zeylanicum) (0,05 a 0,30% v / v) ou de erva doce (Foeniculum vulgare L.) (0,05-0,30 % v / v). A adição do óleo teve como propósito desenvolver uma cobertura com propriedades antimicrobianas, antioxidantes e com capacidade de barreira ao vapor de água, já que os óleos essenciais têm característica hidrofóbica. Foram avaliados estabilidade física, tamanho de gota e viscosidade das coberturas comestíveis emulsionadas e os filmes foram caracterizados através das propriedades mecânicas, solubilidade e microscopia de força atômica. As coberturas emulsionadas com 2% de fécula de mandioca mostraram-se estáveis e as de 3% de fécula apresentaram separação da água do sistema emulsionado. A cobertura foi feitas em fatias de maçãs para o teste de resistência ao vapor de água e medida da taxa de respiração. A formulação com a concentração máxima dos dois óleos essenciais, em ambas as concentrações de fécula de mandioca, resultou em aumento da resistência ao vapor de água. A taxa respiratória das fatias de maçãs com cobertura mostrou efeito de barreira ao CO2 em relação aos frutos sem cobertura. As análises de propriedades mecânicas e microscopia de força atômica dos filmes mostraram que as películas com óleo essencial de casca de canela podem ter apresentado descontinuidade da matriz formadora de filmes. As coberturas com óleo essencial de casca de canela apresentaram efeito significativo para a atividade antioxidante. O teste de halo de inibição dos microrganismos mostrou que a formulação com 0,3% de óleo essencial de casca de canela apresenta uma pequena inibição para Staphylococcus aureus e Salmonella choleraesius
Abstract: Edible coatings formed by a combination of cassava starch (2 and 3% w / v) with essential oil of cinnamon bark (Cinnamomum zeylanicum) (0.05 to 0.30% v / v) or fennel (Foeniculum vulgare L.) (0.05 to 0.30% v / v) were developed and characterized. The addition of oil had the objective of developing a coating with antimicrobial and antioxidant properties and capacity to form a better water vapor barrier, due to the aggregation of the hydrophobic characteristics of essential oil. Physical stability, particle size and viscosity of the edible coatings were analyzed and films were characterized by mechanical properties, solubility and atomic force microscopy measures. Coatings emulsified with 2% cassava starch were stable and the 3% starch concentration with added essential oil showed water separation from the emulsified system. The coatings were applied to apple slices for water vapor resistance and respiration rate tests. The formulation with maximum concentration of both essential oils, at both concentrations of cassava starch, resulted in increased water vapor resistance, and respiration rates of coated apple slices showed a CO2 barrier effect in relation to fruit without coating. Mechanical properties analysis and atomic force microscopy showed that films added with cinnamon bark essential oil presented discontinuity on its matrix-forming capacity. Coating with cinnamon bark essential oil had significant antioxidant capacity. Inhibition of microorganisms tests proved that the formulation with 0.3% essential oil of cinnamon bark had a small inhibiting activity against Staphylococcus aureus and Salmonella choleraesius
Mestrado
Engenharia de Alimentos
Mestra em Engenharia de Alimentos
Erkan, Arcan. "Investigation Of Thin Semiconductor Coatings And Their Antimicrobial Properties". Master's thesis, METU, 2003. http://etd.lib.metu.edu.tr/upload/3/12606306/index.pdf.
S. aereus [Gr (+)] >
S.cerevisiae (yeast) >
A. niger spores. The complexity and the density of the cell walls increased in the same order. As a result of this study, with the coating that shows the best photocatalytic activity, 98% of Escherichia coli, 87% of Staphylococcus aereus, 43% Saccharomyces cerevisiae were killed after 2 hours illumination.
Vangala, Lakshmisri Manisha. "Size Dependent Antimicrobial Properties of Sugar Encapsulated Gold Nanoparticles". TopSCHOLAR®, 2012. http://digitalcommons.wku.edu/theses/1166.
Amengor, Dzifa. "Antimicrobial Properties of Verbesina negrensis Extracts against Helicobacter pylori". Thesis, Southern Illinois University at Edwardsville, 2018. http://pqdtopen.proquest.com/#viewpdf?dispub=10792975.
Helicobacter pylori is a bacterium that can cause chronic gastritis and gastrointestinal cancers in some infected people due to the overexpression of inflammatory cytokines and oxidative stress resulting from accumulation of reactive oxygen species. Verbesina negrensis is a plant that is routinely used in the treatment of gastric complaints. The purpose of this research is to isolate pure bioactive compounds from V. negrensis and evaluate the antimicrobial properties of the isolates against H. pylori. Additionally, we will determine the toxicity of the plant extracts on gastric epithelial cells (NCI-N87) using the MTT assay. We hypothesized that V. negrensis pure compounds would have anti-Helicobacter properties and low cytotoxicity to the epithelial cells. To test this hypothesis pure compounds were isolated from the V. negrensis ethanolic crude extract using silica gel and bioassay guided chromatography. Two pure compounds were isolated AG2 and AQ2B with MICs of 16 µg/mL and 128 µg/mL respectively. AQ2B was cytotoxic to NCI-N87 cells at MIC 128 µg/mL and sub-MIC values of 64, 32 and 16 µg/mL.
Song, Ronghui. "Synthesis, Characterization and Antimicrobial Properties of Novel Naphthoquinone Derivatives". Kent State University / OhioLINK, 2020. http://rave.ohiolink.edu/etdc/view?acc_num=kent1586783242508385.
Rosa, Marguerita Evangelho da. "Production and purification of IgY antibodies with antimicrobial properties". Master's thesis, Universidade de Aveiro, 2017. http://hdl.handle.net/10773/22545.
A Aquacultura tem recebido especial destaque nos últimos anos como alternativa às atividades de pesca tradicional, atualmente restritas pelos limites legais de captura. Neste sentido, têm-se desenvolvido novas técnicas de modo a aumentar o lucro e o rendimento das atividades associadas à aquacultura. No entanto, a sobre-exploração de espécies, poluição, surgimento de doenças e o aumento de microorganismos resistentes a antibióticos, surgem como consequências deste desenvolvimento. Vibrio anguillarum é uma bactéria Gram-negativa que causa infeções em peixes de sistemas de aquacultura e que origina perdas económicas significativas. Estas infeções são normalmente tratadas com recurso a agentes antimicrobianos, tais como antibióticos. No entanto, a prevalência de bactérias resistentes a estes compostos destaca a necessidade crucial de desenvolvimento de estratégias terapêuticas alternativas. O uso de anticorpos, nomeadamente a imunoglobulina Y (IgY) produzidas em aves poedeiras e purificado a partir de gemas de ovos é uma abordagem promissora para o controlo de infeções por V. anguillarum na aquacultura. O atual trabalho centrou-se no desenvolvimento de anticorpos IgY específicos contra os determinantes de virulência associados a V. anguillarum como uma estratégia antimicrobiana capaz de melhorar a produtividade dos sistemas de aquacultura. Neste são apresentados resultados da produção, purificação e caracterização de anticorpos IgY de galinha e codorniz contra antigénios (extratos celulares, frações da membrana externa e péptidos do canal TolC) de V. anguillarum. Aves hiperimunes foram produzidas com sucesso para cada antigénio e foram purificadas as respetivas frações específicas de IgY (> 95% de pureza). Por fim, estudou-se o potencial antimicrobiano dos anticorpos anti-extrato celular de V. anguillarum por ensaios de crescimento bacteriano que revelaram um efeito bacteriostático promissor com 50% de inibição. Em suma, e face aos resultados obtidos, os anticorpos podem ser usados como agentes antimicrobianos alternativos para combater e prevenir infeções por V. anguillarum em sistemas de aquacultura.
Aquaculture has received remarkable attention in recent years as an alternative to traditional fishing activities, currently restricted by fishing quotas. New techniques have therefore been developed to increase production and profit of aquaculture activities. However, over-exploitation, pollution, appearance of infectious diseases and antimicrobial resistance, have emerged as concerning consequences of such development. Vibrio anguillarum is a Gram-negative bacterium causing fish infections in aquaculture systems and leading to significant economic losses. These infections are usually treated with antibiotics; however, the prevalence of bacteria resistant to such drugs urges the development of alternative therapeutic strategies. The use of antibodies, namely avian Immunoglobulin Y (IgY) purified from bird egg yolks, is a promising approach for the control of V. anguillarum infections in aquaculture. The current work focused on the development of specific IgY antibodies against virulence determinants associated to V. anguillarum, envisaging an antimicrobial strategy capable of improving the productivity of aquaculture systems. In this work, the production, purification and characterization of chicken and quail IgY antibodies against V. anguillarum antigens are presented. Whole-cell extracts, outer-membrane fractions and outer-membrane TolC channel peptides were used as antigens in independent protocols to elicit target-specific V. anguillarum antibodies. Hyperimmune birds were successfully generated for each antigen and respective target-specific IgY fractions were purified (>95% purity) from selected bird eggs for downstream studies. Finally, the antimicrobial potential of anti-whole-cell V. anguillarum antibodies was studied by bacterial growth assays, revealing a promising bacteriostatic effect, with 50% of bacterial growth inhibition. In summary, and according to the results obtained, such antibodies can be used as alternative antimicrobial agents to prevent and combat infections by V. anguillarum in aquaculture systems.
Sandhu, Guneev. "Characterization of Lactose Esters for Their Antimicrobial and Emulsification Properties". DigitalCommons@USU, 2014. https://digitalcommons.usu.edu/etd/3855.
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Smith-Palmer, Mary Alison. "The antimicrobial properties of plant essential oils against foodborne pathogens". Thesis, Queen Margaret University, 1999. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.327082.
Belkhair, Sama Salem. "Antimicrobial properties of Ag zeolites and Ag zeolite containing polymers". Thesis, Manchester Metropolitan University, 2016. http://e-space.mmu.ac.uk/617118/.
BERTON, FEDERICO. "BIORESORBABLE ENGINEERED MEMBRANES FOR GUIDED BONE REGENERATION WITH ANTIMICROBIAL PROPERTIES". Doctoral thesis, Università degli Studi di Trieste, 2020. http://hdl.handle.net/11368/2963760.
The main topics of this doctoral thesis are bone regeneration and bone tissue analysis by means of nanotechnological strategies for both purposes. Briefly, the development of nanostructured membranes and scaffolds for bone regeneration procedures in oral surgery have been explored, together with the optimization of analysis protocols at the micro- and nano-scale. The first attempts were addressed to reproduce some of the recent results reported in the scientific literature. Thereafter the necessary components for the ELS process were acquired, assembled and tested. Different combinations of solvents for the preparation of polycaprolactone (PCL) based membranes were tested. Thereafter, an air-plasma cleaning process was applied in order to increase the membrane hydrophilicity. Qualitative characterization of membranes obtained by ELS, before and after plasma treatment has been performed together with the morphological analysis through Scanning Electronic Microscopy. The determination of surface wettability with contact angle measurements was performed. Lactose-modified chitosan (CTL) was added by chemical adsorption on PCL membranes in order to increase their bioactivity. Confocal microscopy analysis showed an improved adsorption of CTL for the membranes treated with air-plasma if compared with the untreated ones. Moreover, CTL was used to deliver, on the membranes, silver nanoparticles (nAg) synthesized within CTL solution. ETAAS analysis, performed to quantify nAg, showed a higher nAg content in membranes treated with a low energy air-plasma treatment and CTL-nAg at pH 7, thus confirming Raman findings. MG63 cells cultured on PCL membranes with or without CTL, showed a more sustained growth after 7 days on the CTL-coated membranes compared with untreated PCL membranes and PCL air-plasma treated membranes. Moreover, the presence of nAg did not hamper cell viability with respect to PCL membranes, as confirmed by lactate dehydrogenase (LDH) assay. The antibacterial activity of PCL-nAg membranes was tested in terms of biofilm inhibition on Pseudomonas aeruginosa (ATCC 27853) and Staphylococcus aureus (ATCC 25923), using the MTT test. The viability data and the SEM imaging clearly showed that the biofilm formation was strongly inhibited on the surface of PCL-CTL-nAg membranes. Mechanical resistance of the produced membranes, soaked and aged in Simulated Body Fluid (SBF) was tested by means of uniaxial tensile tests for the evaluation of elastic modulus and maximal deformation and stress. As second chapter of this thesis, the potentiality of another approach to produce nanostructured fibrin-based membranes was explored. These membranes were obtained by means of blood centrifugation and were tailored with bone-inducing molecule, such as nano-hydroxyapatite (nHAp). Thus, the durability of pristine membrane in SBF was tested. At each time point, one sample was analyzed with SEM with ImageJ processing tools revealing a mean fiber diameter of 0.103 ± 0.05µm without any statistically significant differences during time; degradation assay showed a two-folds increase of the weight related to the SBF absorption in the first 2 days. From the third day a constant degradation was observed. In the time frame of this experiment, the dimensional stability of the fibrin structure up to day 7 suggested that PRF membranes may also be used uncovered in the oral cavity. Subsequently, the effects of the nHAp addition during the forming process of PRF (thus during centrifugation) were investigated. As all the above-mentioned techniques were oriented to regenerate maxillofacial bone, a bone histomorphometric analysis protocol that, at the time of writing of the present thesis, was not already present in the University of Trieste) was optimized. This protocol was prepared and implemented with the ultrastructural SEM-EDS (Energy Dispersive Spectroscopy) analysis of hard tissues mounted on the histological slides).
Chindera, Kantaraja. "Cell uptake properties of Polyhexamethylene Biguanide (PHMB) and applications in intracellular delivery". Thesis, Royal Veterinary College (University of London), 2014. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.618319.
Gilles, Martin. "Screening of the antimicrobial properties of four Australian native Eucalyptus species /". Sion, 2007. http://doc.rero.ch/search.py?recid=8350&ln=fr.
Fitzgerald, Daniel J. "Investigation of the antimicrobial properties of the phenolic flavour compound vanillin". Thesis, University of East Anglia, 2003. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.273578.
Gledhill, L. "Antimicrobial and beta-lactamase inhibitory properties of chlorinated 6-spiro-epoxypenicillins". Thesis, University of Nottingham, 1988. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.233715.
Wong, Sze Yinn (Sze Yinn Jessie). "Polyelectrolyte multilayer thin films with antimicrobial, antifouling and drug releasing properties". Thesis, Massachusetts Institute of Technology, 2011. http://hdl.handle.net/1721.1/65768.
Cataloged from PDF version of thesis.
Includes bibliographical references (p. 152-160).
This thesis work focuses on designing thin polyelectrolyte multilayer (PEM) films via layer-bylayer (LbL) deposition technique with the ability to kill pathogenic bacteria and inactivate human viruses, especially the influenza (flu) virus on contact. This work builds on four years of research at the Institute for Soldier Nanotechnologies (ISN) focusing on creating new, nonleaching microbicidal material; this film is envisioned to be used as permanent surface coatings for weapons, equipments, uniforms, personal items, etc. because a small reduction in the rate of infection will greatly enhance the readiness and performance of soldiers and other military personnel. Extending this application to everyday life, commonly handled objects such as doorknobs, computer keyboards, and touch screens can also be made sterile by coating them with these highly effective microbicidal PEM films. These films can also be used to prevent infections and long-term bacterial biofilms on implant surfaces. The ultimate aim of this thesis work is to create a broadly applicable multifunctional platform film technology that will satisfy various thin film surface coating applications; this film will impart a surface with long term antimicrobial / antifouling functionality via a permanent microbicidal base, and controlled delivery of a therapeutic agent via a hydrolytically degradable top film as needed. Efforts were focused on maximizing and understanding the factors that influence the microbicidal / antifouling property of the film; thus far, we successfully designed a set of contact-killing ionically cross-linked polymeric thin films; a hydrophobic polycation, linear NNdodecyl, methyl- poly(ethylenimine) (DMLPEI) with microbicidal activity was layered with a hydrophilic polyanion, such as poly(acrylic acid) (PAA), to create LbL films highly effective against Escherichia coli and Staphylococcus aureus (Gram negative and positive bacteria, respectively), as well as the influenza A/WSN (H1N1) virus. The microbicidal film was also demonstrated to significantly resist adsorption of protein from blood plasma relative to an uncoated substrate. By generating PEM films assembled with the hydrophobic N-alkylated poly(ethylenimine) and the hydrophilic poly(acrylic acid), an ultrathin film that exhibited antifouling and antimicrobial properties was created. Results showed that a fine balance of hydrophobicity and hydrophilicity on the surface of the films was needed to create molecularlevel heterogeneities unfavorable to protein adsorption; due to the contrasting nature of the polymer making up the film, nanoscale segregation of the polymer segments into hydrophobic and hydrophilic moieties could occur on the surface. We then moved on to design a dual functional LbL film construct combining the permanent microbicidal / antifouling base film with a hydrolytically degradable PEM top film offering controlled and localized delivery of therapeutics (e.g. antibiotic, anti-inflammatory drug, etc.). When the degradable top film is completely eroded, the surface will be left with the permanent microbicidal film for long-term prevention of fouling by biomolecules and microorganisms (e.g., proteins and bacteria).
by Sze Yinn (Jessie) Wong.
Ph.D.
Melaiye, Abdulkareem M. "Synthesis and Antimicrobial Properties of Silver(I) N-Heterocyclic Carbene Complexes". University of Akron / OhioLINK, 2005. http://rave.ohiolink.edu/etdc/view?acc_num=akron1124310734.
Mody, Shreena Himanshu. "The Antimicrobial Properties of Honey and Their Effect on Pathogenic Bacteria". BYU ScholarsArchive, 2018. https://scholarsarchive.byu.edu/etd/7042.
Bensaci, Mekki F. "The Bioactive Properties of Syringomycin E-Rhamnolipid Mixtures and Syringopeptins". DigitalCommons@USU, 2009. https://digitalcommons.usu.edu/etd/247.
Zhang, Manrui. "Studies of a click reaction route to antimicrobial polymer latexes". Thesis, University of Manchester, 2017. https://www.research.manchester.ac.uk/portal/en/theses/studies-of-a-click-reaction-route-to-antimicrobial-polymer-latexes(b6c2b634-ec41-44b6-a88f-2d908e1f422c).html.
Xu, Youhong. "Adaptive immune response-modifying and antimicrobial properties of Andrographis paniculata and andrographolide". University of Southern Queensland, Faculty of Sciences, 2009. http://eprints.usq.edu.au/archive/00005134/.
Kwok, Hoi-shan, e 郭凱珊. "The comparison of biological properties of L- and D-enantiomeric antimicrobial peptides". Thesis, The University of Hong Kong (Pokfulam, Hong Kong), 2014. http://hdl.handle.net/10722/206507.
published_or_final_version
Pharmacology and Pharmacy
Master
Master of Medical Sciences
Mann, Maryssa Gudrun Ailsa. "An investigation of the antimicrobial and antifouling properties of marine algal metabolites". Thesis, Rhodes University, 2008. http://hdl.handle.net/10962/d1007465.
KMBT_363
Adobe Acrobat 9.54 Paper Capture Plug-in
Hetrick, Evan M. Schoenfisch Mark H. "Antimicrobial and wound healing properties of nitric oxidereleasing xerogels and silica nanoparticles". Chapel Hill, N.C. : University of North Carolina at Chapel Hill, 2008. http://dc.lib.unc.edu/u?/etd,1928.
Title from electronic title page (viewed Dec. 11, 2008). "... in partial fulfillment of the requirements for the degree of Doctor of Philosophy in the Department of Chemistry Analytical Chemistry." Discipline: Chemistry; Department/School: Chemistry.
Torrey, Jason Robert. "Antimicrobial Properties Of Metal And Metal-Halide Nanoparticles And Their Potential Applications". Diss., The University of Arizona, 2014. http://hdl.handle.net/10150/338682.
Korshed, Peri. "The molecular mechanisms of the antimicrobial properties of laser processed nano-particles". Thesis, University of Manchester, 2018. https://www.research.manchester.ac.uk/portal/en/theses/the-molecular-mechanisms-of-the-antimicrobial-properties-of-laser-processed-nanoparticles(731afee1-17f3-4698-b182-b604fb48492f).html.
Dodge, Luke A. "FRACTIONATION OF LIGNIN DERIVED COMPOUNDS FROM THERMOCHEMICALLY PROCESSED LIGNIN TOWARDS ANTIMICROBIAL PROPERTIES". UKnowledge, 2018. https://uknowledge.uky.edu/bae_etds/54.
Munir, Muhammad Tanveer. "Wood and hospital hygiene : Investigating the hygienic safety and antimicrobial properties of wood materials". Thesis, Ecole centrale de Nantes, 2021. http://www.theses.fr/2021ECDN0008.
The wood material provides a nature-based theme to construction because of its natural appearance, ecofriendly nature and biophilic effects on humans. However, its organic and porous nature is questioned when using it in hygienically important places such as hospitals. Studies have shown that wood has antimicrobial properties against some pathogens; work is still needed, however, to demonstrate this antimicrobial action and its relation to wood and microbiological variables. This research gathers and generates information to guide stakeholders of hospital hygiene on the hygienic safety of wood materials. First, a simple and direct method was developed to study the antibacterial and antifungal activity of solid wood, which also identified the role of wood and microbial variables on antimicrobial behavior. Further, an elution based bacterial recovery method was investigated which showed that the most common nosocomial bacteria did not survive as well on wood as compared to smooth surfaces such as aluminum, steel and polycarbonate. Meanwhile, an innovative tool was developed, involving the use of fluorescent probes to study the bacterial distribution on and inside wood using confocal spectral laser microscopy. These experiments produced the information that will help the decision makers regarding the choice of wood material in the healthcare buildings. It not only enhances our understanding of hygienic safety of wood in healthcare buildings but also provides the basis for future research on the prevalence of pathogens in the wooden healthcare institutes and the perception of the occupants those buildings
Zhang, Tian. "Investigation of The Structure-Property Correlations of Pendent Functionalized Antimicrobial Polyurethanes". University of Akron / OhioLINK, 2018. http://rave.ohiolink.edu/etdc/view?acc_num=akron1522936710295726.
Korkmaz, Erdural Beril. "Photocatalytic Antimicrobial And Self-cleaning Properties Of Titania-silica Mixed Oxide Thin Films". Phd thesis, METU, 2012. http://etd.lib.metu.edu.tr/upload/12615137/index.pdf.
Deyrieux, Charlotte. "Identification, characterisation and application of plant extracts with combined antioxidant and antimicrobial properties". Thesis, Montpellier, 2018. http://www.theses.fr/2018MONTG070.
Oxidation and microbial growth are the major parameters causing the deterioration of food products, including pet food. These degradations affect the nutritional and sensory qualities of the products and may lead to health issues. In this context, various ways of prevention are available to limit these phenomena. Among them, the promotion of plant extracts for food is a major challenge for research and industry. Their use as natural preservatives could be an attractive alternative to synthetic antioxidants or antimicrobials that suffer from lower consumer acceptance.Through this study we have identified and characterized the performance of fifteen plant extracts from an antioxidant and antimicrobial point of view. After a molecular characterization of the extracts, their antioxidant capacity was measured as well as their antimicrobial property on three Salmonella strains. The establishment of a selection procedure was made. Finally, the extracts presenting the most interesting characteristics were tested on a real food matrix: kibbles
Oree, Glynis. "Chitin hydrolysis with chitinolytic enzymes for the production of chitooligomers with antimicrobial properties". Thesis, Rhodes University, 2019. http://hdl.handle.net/10962/67887.
Van, der Vyver Petrus Jacobus. "Antimicrobial properties and smear layer management of nine different root canal irrigation solutions". Diss., Pretoria : [s.n.], 2007. http://upetd.up.ac.za/thesis/available/etd-082222008-163721/.
Al-Dulaimi, Omar Ahmed Abass. "Phytochemical composition and antimicrobial properties of four plants indicated for traditional medicine use". Thesis, Keele University, 2017. http://eprints.keele.ac.uk/3078/.
CALAMELLO, CATERINA. "TRP ACTIVE COMPOUNDS FROM FOOD PLANTS AND THEIR PROPERTIES AS ANTIMICROBIAL AND BIOCIDES". Doctoral thesis, Università degli Studi di Milano, 2012. http://hdl.handle.net/2434/168879.