Tesi sul tema "Antibacterial agents"
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Zhang, Huichun. "Metal oxide-facilitated oxidation of antibacterial agents". Diss., Available online, Georgia Institute of Technology, 2004:, 2004. http://etd.gatech.edu/theses/available/etd-07072004-152317/unrestricted/zhang%5Fhuichun%5F200407%5Fphd.pdf.
Testo completoWine, Paul, Committee Member ; Pavlostathis, Spyros, Committee Member ; Mulholland, James, Committee Member ; Yiacoumi, Sotira, Committee Member ; Huang, Ching-Hua, Committee Chair. Includes bibliographical references.
Tan, Jinlong. "Design and Synthesis of Novel Antibacterial Agents". Thesis, The University of Sydney, 2021. https://hdl.handle.net/2123/25809.
Testo completoMarshall, Neil J. "Antibacterial agents designed to exploit peptide transport systems". Thesis, Bangor University, 1994. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.262012.
Testo completoPenishkevich, Ya. "Ophthalmic topical antibacterial agents: current and evolving options". Thesis, БДМУ, 2020. http://dspace.bsmu.edu.ua:8080/xmlui/handle/123456789/18146.
Testo completoSmith, Nichola Ann. "Photoactivatable Ru(II) polypyridyl complexes as antibacterial agents". Thesis, University of Warwick, 2015. http://wrap.warwick.ac.uk/76173/.
Testo completoNielsen, Elisabet I. "Pharmacometric Models for Antibacterial Agents to Improve Dosing Strategies". Doctoral thesis, Uppsala universitet, Institutionen för farmaceutisk biovetenskap, 2011. http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-144909.
Testo completoDas, Sanjan Kumar. "Application of Structural Genomics for Developing Novel Antibacterial Agents". Thesis, University of Sheffield, 2007. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.486462.
Testo completoGriffiths, Jennifer Mary. "Model systems to investigate bacterial persistence to antibacterial agents". Thesis, University of Leeds, 2012. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.590484.
Testo completoCarraco, Moreira Joao Bruno. "Characterisation of symmetric bis-benzimidazoles as antibacterial chemotherapeutic agents". Thesis, University of London, 2012. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.579712.
Testo completoLam, Chi-wah. "Antibacterial effects of nanoparticles on cariogenic organisms /". View the Table of Contents & Abstract, 2005. http://sunzi.lib.hku.hk/hkuto/record/B31490414.
Testo completoIsmaeel, N. A.-A. "Resistance of Providencia stuartii to chlorhexidine and other antibacterial agents". Thesis, Cardiff University, 1987. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.376556.
Testo completoBaguley, Christina Birgit. "The structure and activity of #beta#-lactamase I from Bacillus cereus". Thesis, University of Oxford, 1990. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.279880.
Testo completoO'Leary, Ruth. "Investigation into the modification of the A-ring of analogues of 4-quinolones". Thesis, University of Strathclyde, 1988. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.303283.
Testo completoShojaee, Aliabadi Fariborz. "Danofloxacin pharmacodynamic and pharmacokinetic interrelationships in ruminant species". Thesis, Royal Veterinary College (University of London), 1997. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.266348.
Testo completoMiller, Chandra Tier. "The design, synthesis and screening of naphthalene diimides with antibacterial activity /". Digital version accessible at:, 1999. http://wwwlib.umi.com/cr/utexas/main.
Testo completoHendry, Maureen M. "The efficacy of topical honey to heal wounds and burns : systematic review and meta-analysis /". [St. Lucia, Qld.], 2001. http://www.library.uq.edu.au/pdfserve.php?image=thesisabs/absthe16941.pdf.
Testo completo林志華 e Chi-wah Lam. "Antibacterial effects of nanoparticles on cariogenic organisms". Thesis, The University of Hong Kong (Pokfulam, Hong Kong), 2005. http://hub.hku.hk/bib/B45007743.
Testo completoAcquaah-Harrison, George. "Antibacterial Agents: 1,4-Disubstituted 1,2,3-Triazole Analogs of the Oxazolidinone". Ohio : Ohio University, 2010. http://www.ohiolink.edu/etd/view.cgi?ohiou1273250347.
Testo completoJackson, Andrew Edward. "A novel approach to #beta#-lactam and quinolone antibacterial agents". Thesis, University of Sunderland, 1997. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.242127.
Testo completoSalama, Fatma Ibrahim Khalifa. "Exploring the potential of Affimer artificial antibodies as antibacterial agents". Thesis, University of Leeds, 2017. http://etheses.whiterose.ac.uk/19935/.
Testo completoGlansdorp, Freija Gwendolyn. "Chemical studies into novel modes of action of antibacterial agents". Thesis, University of Cambridge, 2008. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.611932.
Testo completoKasturiarachchi, Jagath Chandana. "Bio-oligomers as antibacterial agents and strategies for bacterial detection". Thesis, University of Edinburgh, 2014. http://hdl.handle.net/1842/10030.
Testo completoCarrick, Christopher. "Exploiting bacterial transporters for the design of novel antibacterial agents". Thesis, University of York, 2014. http://etheses.whiterose.ac.uk/6533/.
Testo completoZhang, Jianjun. "Library Synthesis of Anticancer and Antibacterial Agents via Azide Chemistry". DigitalCommons@USU, 2010. https://digitalcommons.usu.edu/etd/711.
Testo completoChiodini, G. "SYNTHESIS AND DEVELOPMENT OF NEW ANTIBACTERIAL AGENTS INHIBITORS OF FTSZ". Doctoral thesis, Università degli Studi di Milano, 2014. http://hdl.handle.net/2434/232409.
Testo completoTshanga, Siphokazi Sisanda. "Antibacterial activity of liposome encapsulated cyclo(TYR-PRO)". Thesis, Nelson Mandela Metropolitan University, 2011. http://hdl.handle.net/10948/1450.
Testo completoEl-Falaha, B. M. A. "Resistance to antibacterial agents : studies with Escherichia coli and Pseudomonas aeruginosa". Thesis, Cardiff University, 1985. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.304154.
Testo completoElla-Menye, Jean-Rene. "Synthesis of Novel Chiral Heterocyclic Compounds for Antibacterial Agents and Peptidomimetics". ScholarWorks@UNO, 2007. http://scholarworks.uno.edu/td/611.
Testo completoDoss, Sally. "The role of antibacterial agents on the pathogenicity of Staphylococcus aureus". Thesis, University of Edinburgh, 1992. http://hdl.handle.net/1842/19698.
Testo completoShapiro, Elyse M. "Optimizing Escherichia coli for the detection of antimicrobial compounds /". Thesis, Connect to this title online; UW restricted, 2005. http://hdl.handle.net/1773/9916.
Testo completoSpencer, William T. "Part I, studies toward the total synthesis of Trocheliophorolide A. ; part II, studies on the development of a palladium-catalyzed carbonylative cross-coupling towards the synthesis of alkenyl alkynyl ketones /". Online version of thesis, 2008. http://hdl.handle.net/1850/7729.
Testo completoRigoreau, Laurent Jean Martin. "The synthesis of β-Sultams". Thesis, University of Huddersfield, 1999. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.323939.
Testo completoBandara, Bandarage Mahesh Kithsiri Optometry & Vision Science Faculty of Science UNSW. "Investigation and characterisation of antibacterial properties of non-steroidal anti-inflammatory drugs". Awarded by:University of New South Wales. School of Optometry and Vision Science, 2005. http://handle.unsw.edu.au/1959.4/22284.
Testo completoCarlsson, Stefan. "Antibacterial effects of nitrite in urine /". Stockholm : Karolinska institutet, 2005. http://diss.kib.ki.se/2005/91-7140-237-3.
Testo completoSingh, G. "Antibacterial activity testing of cotton medical textiles sonochemically impregnated with metal oxide nanoparticles". Thesis, Coventry University, 2014. http://curve.coventry.ac.uk/open/items/edeb833b-a792-49eb-bc22-bafbd374bb22/1.
Testo completoMbere, Johana M. "Development of new benzo[b]thiophene amide-based antimicrobial agents". Department of Chemistry - Faculty of Science, 2005. http://ro.uow.edu.au/theses/396.
Testo completoClarke, Annette June Morgan. "The physical characterization and antibacterial activity of herring protamines". Thesis, National Library of Canada = Bibliothèque nationale du Canada, 1998. http://www.collectionscanada.ca/obj/s4/f2/dsk1/tape10/PQDD_0029/MQ47419.pdf.
Testo completoFleeman, Renee. "Discovering Antibacterial and Anti-Resistance Agents Targeting Multi-Drug Resistant ESKAPE Pathogens". Scholar Commons, 2017. http://scholarcommons.usf.edu/etd/6839.
Testo completoProvost, Paul Graham. "The persistence and effects of antibacterial agents in marine fish farm sediments". Thesis, Edinburgh Napier University, 1996. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.369173.
Testo completoPan, Po-Shen. "Synthesis of macrocycles and their biological evaluation as antitumor and antibacterial agents". Diss., Connect to a 24 p. preview or request complete full text in PDF format. Access restricted to UC campuses, 2008. http://wwwlib.umi.com/cr/ucsd/fullcit?p3320912.
Testo completoTitle from first page of PDF file (viewed October 3, 2008). Available via ProQuest Digital Dissertations. Vita. Includes bibliographical references.
Meng, Fan Cheng. "Chemical constituents from the rhizome of coptis chinensis and their antibacterial activities". Thesis, University of Macau, 2018. http://umaclib3.umac.mo/record=b3953272.
Testo completoMariner, Katherine Ruth. "The activity, mode of action and generation of resistance to novel antibacterial agents". Thesis, University of Leeds, 2011. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.659123.
Testo completoGonciarz, Ryan Lennox. "Broadening the spectrum of antibacterial agents to tackle multidrug-resistant Gram-negative pathogens". Thesis, University of Leeds, 2018. http://etheses.whiterose.ac.uk/22308/.
Testo completoPaula-Eduardo, Laila Facin de 1984. "Isolamento e identificação de compostos bioativos da geoprópolis (Melipona scutellaris) bioguiado pelo efeito antimicrobiano = Isolation and identification of bioactive compounds of geopropolis (Melipona scutellaris) bioguided by the antimicrobial effect". [s.n.], 2014. http://repositorio.unicamp.br/jspui/handle/REPOSIP/288513.
Testo completoDissertação (mestrado) - Universidade Estadual de Campinas, Faculdade de Odontologia de Piracicaba
Made available in DSpace on 2018-08-26T11:28:01Z (GMT). No. of bitstreams: 1 Paula-Eduardo_LailaFacinde_M.pdf: 1396217 bytes, checksum: ee32ae3fccb5fc73fe047b8152a78b6e (MD5) Previous issue date: 2014
Resumo: Os produtos naturais, comprovadamente, têm sido uma fonte promissora para descoberta de novos compostos bioativos. Dentre eles, a própolis coletada por abelhas Apis mellifera possui atividades biológicas descritas na literatura como anticárie, antibacteriana, anti-inflamatória, entre outras. Entretanto, a maioria dos estudos sobre própolis se refere àquelas coletadas por A. mellifera e pouco se tem conhecimento de outras, como a geoprópolis, produzida por abelhas sem ferrão do gênero Melipona. Em estudos recentes, a geoprópolis apresentou promissoras atividades antimicrobiana e anti-inflamatória, porém estas pesquisas ainda não evidenciaram quais as substâncias responsáveis por tais ações biológicas, especialmente contra o biofilme oral cariogênico. Portanto, o objetivo desse trabalho foi isolar e identificar o composto ativo da geoprópolis de Melipona scutellaris com atividade contra biofilme formado por Streptococcus mutans. Este objetivo foi alcançado por meio das seguintes metodologias: 1- fracionamento bioguiado do extrato etanólico da geoprópolis (EEGP); 2- isolamento e identificação do composto ativo; 3- avaliação do potencial anticárie do composto ativo utilizando modelo in vitro de inibição de biofilme oral monoespécie. Como resultado do fracionamento bioguiado foi isolado e identificado o composto nemorosona (C33H42O4, MM= 502 g/mol), uma benzofenona prenilada. A concentração inibitória mínima da nemorosona foi de 6,25 ¿ 12,5 ?g/mL e na concentração de 100 ?g/mL foi capaz de inibir em 95% a aderência do S. mutans em biofilme formado em microplacas de fundo côncavo. Em biofilme formado em discos de hidroxiapatita, a nemorosona na concentração 250 ?g/mL (0,50 mM) reduziu 65 % do peso seco, mais de 70% dos polissacarídeos e 48% da quantidade proteica além de diminuir a viabilidade bacteriana, quando comparada com o controle negativo (veículo, p<0,05). Estes resultados não diferiram estatisticamente da clorexidina a 0,12% (1,33 mM) (p>0,05). Portanto, concluímos que a nemorosona é um composto ativo isolado e identificado da geoprópolis com atividade antibiofilme de S. mutans com capacidade de alterar a composição bioquímica da matriz do biofilme de S. mutans, o que torna este composto promissor agente químico para o controle do biofilme oral
Abstract: Natural products have been demonstrated a promising source to discover new bioactive compounds. Among then, the propolis collected by Apis mellifera bees has biological activity described in the literature as anticairies, antimicrobial, anti-inflammatory, besides other activities. However, most of the studies on propolis refer to those collected by A. mellifera and little is known about others as geopropolis, which is collected by stingless bees of the genus Melipona. In recent studies, geopropolis presented promising antimicrobial and anti-inflammatory activities, but these studies have not revealed which is (are) the substance(s) responsible(s) for such biological activities, especially against the cariogenic oral biofilms. Therefore, the objective of this study was to isolate and identify the active compound from Melipona scutellaris geopropolis, which has activity against the biofilm formation by Streptococcus mutans. This goal was achieved by the following methodologies: 1- bioassay-guided fractionation of the goeporpolis ethanolic extract (EEGP); 2- isolation and identification of the active compound; 3- anticarie potential assessment of the active compound using an in vitro model of inhibition of the oral mono-species biofilm. As result of the bioassay-guided fractionation, the poliprenil benzophenone compound named nemorosone (C33H42O4, MW=502 g/mol) was isolated and identified. The nemorosone¿s minimum inhibitory concentration (MIC) was 6.25 ¿ 12.5 ?g/mL and the concentration of 100 ?g/mL was capable to inhibit by 95% the adherence of S. mutans¿s biofilm formed in U-bottom microtiter plates. In biofilm formed in hydroxyapatite disks, the nemorosone concentration of 250 ?g/mL (0.5 mM) reduced 65% of the dry weight, more than 70% of the polysaccharides and 48% of the protein content. In addition, it reduced the bacterial viability when compared to negative control (vehicle, p<0.05). These results did not differ statistically from chlorhexidine 0.12% (1.33 mM) (p> 0.05). Therefore, the conclusion is that nemorosone is the active compound isolated and identified from geopropolis with antibiofilm activity that is able to alter the biochemical composition of the S. mutans biofilm matrix, it makes this chemical compound promising to oral biofilm control
Mestrado
Farmacologia, Anestesiologia e Terapeutica
Mestra em Odontologia
Riesbeck, Kristian. "Effects of fluoroquinolones on the immune system". Malmö : Dept. of Medical Microbiology, Lund University, Malmö General Hospital, 1994. http://books.google.com/books?id=-hRtAAAAMAAJ.
Testo completoMartini, Nataly Dominica. "The isolation and characterisation of antibacterial compounds from Combretum erythrophyllum (Burch.) Sond". Diss., Pretoria : [s.n.], 2001. http://upetd.up.ac.za/thesis/available/etd-07092002-153815/.
Testo completoMoro, Whitney Beysselance. "The design and synthesis of antibacterial inhibitors of NAD synthetase". Birmingham, Ala. : University of Alabama at Birmingham, 2007. https://www.mhsl.uab.edu/dt/2009r/moro.pdf.
Testo completoTitle from PDF title page (viewed Feb. 4, 2010). Additional advisors: Subramaniam Ananthan, David E. Graves, Craig D. Smith, Sadanandan E. Velu. Includes bibliographical references.
Lo, Shiu-hong. "Antibacterial activity of some marine planktonic algae in Hong Kong /". Hong Kong : University of Hong Kong, 1996. http://sunzi.lib.hku.hk/hkuto/record.jsp?B19667152.
Testo completoSitnikov, Dmitri. "Toxicity and adsorbance abilities of Alcell lignin to bacteria". Thesis, McGill University, 1999. http://digitool.Library.McGill.CA:80/R/?func=dbin-jump-full&object_id=29807.
Testo completoThe antibacterial activity was delayed by the inclusion of Mg 2+ ions in the AlcellRTMlignin filtrate or in the enumeration medium (BHIA). Addition of bile salts to the enumeration medium (BHIA) enhanced the culturability loss of E. coli cells suspended in the filtrate of AlcellRTMlignin. Using FTIR methodology, it appears, that compounds of AlcellRTMlignin affect phospholipid-phospholipid and/or phospholipid-protein interactions in bacterial membranes, causing the patching of membrane phospholipids and proteins.
Additional studies are necessary to evaluate interactions of compounds of AlcellRTMlignin with bacterial cells.
Messina, Maria Cipolla 1961. "The effect of liquid smoke on Listeria monocytogenes". Thesis, The University of Arizona, 1988. http://hdl.handle.net/10150/276677.
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