Letteratura scientifica selezionata sul tema "Alcoholism – Diagnosis"

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Articoli di riviste sul tema "Alcoholism – Diagnosis"

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Mullan, M. J., H. M. D. Gurling, B. E. Oppenheim e R. M. Murray. "The Relationship between Alcoholism and Neurosis:". British Journal of Psychiatry 148, n. 4 (aprile 1986): 435–41. http://dx.doi.org/10.1192/bjp.148.4.435.

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The twin register of the Maudsley Hospital was used to select a series of monozygotic (MZ) and same-sexed dizygotic (DZ) twins who had been given an ICD8 diagnosis related to alcoholism. They and their co-twins were traced. Medical and drinking histories were compiled (from records and by interview) for 56 twin-pairs, to permit current and retrospective diagnosis of any neurotic disorders. RDC diagnoses of panic disorder generalised anxiety disorder, obsessive–compulsive disorder and phobias were more common in the alcoholic probands and the co-twins who were also alcoholics than in the normal-drinking co-twins. The Eysenck Personality Questionnaire (EPQ) and the Severity of Alcohol Dependence Questionnaire (SADQ) were completed by 54 individuals. Neuroticism scores were significantly higher for both male and female alcoholics than for their normal-drinking co-twins; and intra-pair differences in neuroticism were significantly correlated with intra-pair differences in severity of dependence. These results suggest that both clinically diagnosed neurotic illness and high neuroticism scores are more often a consequence than a cause of alcoholism.
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van Gool, W. A. "Alcoholism and dementia". Acta Neuropsychiatrica 3, n. 2 (giugno 1991): 26–29. http://dx.doi.org/10.1017/s092427080003502x.

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SummaryThe controversy concerning the concept ‘alcoholic dementia’ is reviewed in brief. Evidence from neuroradiological and neuropathological studies contribute little to the solution of this controversy, if dementia is considered as a clinical syndrome. From clinical descriptions it can be concluded that a sub-population of alcoholics suffers from a syndrome typified by psychologic disturbances other than amnesia alone. These patients fulfill the criteria for the syndromal diagnosis of ‘dementia’.The nosologic concept of ‘alcoholic dementia’ implies a direct neurotoxic effect of alcohol and it raises questions concerning pathogenetic mechanisms which can not be answered. The DSM-III-R category ‘dementia associated with alcoholism’ represents a solution for this controversy, because it gives a correct and complete (radically syndromal) clinical description without making assumptions on the relative contribution of multiple factors causing cognitive disturbances in alcoholics.
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Schuckit, Marc A., e Michael Irwin. "Diagnosis of Alcoholism". Medical Clinics of North America 72, n. 5 (settembre 1988): 1133–53. http://dx.doi.org/10.1016/s0025-7125(16)30733-7.

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Bernadt, Morris W., e Robin M. Murray. "Psychiatric Disorder, Drinking and Alcoholism:". British Journal of Psychiatry 148, n. 4 (aprile 1986): 393–400. http://dx.doi.org/10.1192/bjp.148.4.393.

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We studied 371 psychiatric admissions in an attempt to relate primary and secondary diagnosis, psychopathology, and stated reasons for drinking to alcohol consumption and alcoholism. No diagnostic group other than the alcoholics drank significantly more than the mean, and the schizophrenics drank less. One-third of those with bipolar and minor depression increased their drinking in the month before admission, but this was almost offset by those with similar diagnoses who drank less. Alcoholism, though not alcohol consumption, was related to a high prevalence of affective syndromes, but these did not amount to secondary diagnoses. Drinking for ‘escape reasons' was significantly associated with consumption levels, but the reasons patients gave did not correspond well with the objective presence or severity of the associated psychiatric symptoms.
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Martin, M. W. "Alcoholism. Recognizing the diagnosis". JAMA: The Journal of the American Medical Association 261, n. 16 (28 aprile 1989): 2446. http://dx.doi.org/10.1001/jama.261.16.2446.

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Ray, R., D. K. Subbakrishna, M. Gentiana, T. Neeliyara e N. G. Desai. "Alcoholism — assessment and diagnosis". Drug and Alcohol Dependence 23, n. 1 (gennaio 1989): 79–81. http://dx.doi.org/10.1016/0376-8716(89)90037-9.

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Das, Subir Kumar, e D. M. Vasudevan. "Biochemical diagnosis of alcoholism". Indian Journal of Clinical Biochemistry 20, n. 1 (gennaio 2005): 35–42. http://dx.doi.org/10.1007/bf02893039.

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Gorwood, P., P. Batel, L. Gouya, F. Courtois, J. Feingold e J. Adès. "Reappraisal of the association between the DRD2 gene, alcoholism and addiction". European Psychiatry 15, n. 2 (marzo 2000): 90–96. http://dx.doi.org/10.1016/s0924-9338(00)00207-8.

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SummaryWe analysed the impact of the TaqI A1 allele of the D2 dopamine receptor gene on the risk for alcoholism, trying to depict three explanations frequently proposed to explain discrepancies in association and linkage studies: that the A1 allele may act as a marker rather than as a vulnerability factor, that stratification biases and unevaluated controls may explain positive results, and that the A1 allele is modifying the phenotype rather than increasing the risk for alcoholism. We thus tested another (dinucleotide STRP) marker within the DRD2 gene, selected a new homogenous sample of 113 alcoholic patients and 49 unaffected controls strictly matched for ethnic origins, and systematically assessed both samples with a semi-structured interview to detect (in both samples) alcohol dependence, but also such related traits as specificities of complications.The frequency of the A1 allele was not significantly different between alcoholics and controls but when comparing different subgroups of alcoholics, the A1 allele was significantly more frequent in alcoholic patients with somatic complications (OR = 3.00, CI[1.37-6.62]), social and professional complications (OR = 2.72, CI[1.25-5.90]), or with co-morbid dependence (OR = 2.88, 95% IC [1.16-7.15]). The association for co-morbid dependence and somatic complications was also positive when taking into consideration both STRP and TaqIA polymorphisms.The A1 allele does not increase the risk for alcoholism per se in our sample, but may be involved in a related trait which is partially dependent on the diagnosis of alcoholism, through a disequilibrium with another close mutation.
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Smith, Annette R. "Alcoholism and Gender: Patterns of Diagnosis and Response". Journal of Drug Issues 16, n. 3 (luglio 1986): 407–20. http://dx.doi.org/10.1177/002204268601600307.

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Through in-depth interviews with 10(ten) male and 10(ten) female self-identified recovering alcoholics, this study examines the gender-related differences in pathways to alcoholism diagnosis and treatment. Respondents' stories suggest that while denial of the diagnosis delays appropriate treatment for both men and women, gender-related differences in the nature of the denial systems, such as who makes the diagnosis, who responds to it and how, keep women from such treatment more often than men. This applies irrespective of other gender differences in actual drinking behavior or rationale, symptoms (including psychopathology), time of onset or course of illness.
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Carney, Michael WP, e Brian F. Sheffield. "Alcoholism diagnosis and Celtic names". Irish Journal of Psychological Medicine 12, n. 3 (settembre 1995): 95–100. http://dx.doi.org/10.1017/s0790966700014518.

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AbstractObjective: To investigate assertions that Celts have higher rates of alcoholism and mental illness than non-Celts.Method: The records of 3,000 admissions to Northwick Park Hospital Psychiatric Unit, Harrow (a North West London suburban middle class borough research hospital with a strictly defined catchment area – the London Borough of Harrow: population 200,000), from June 1987 for three years under the clinical care of four consultant psychiatrists, were examined.Results: There were 683 with non-Celtic names and 175 with Celtic names (16.7%) (data on 10 patients incomplete). 306 (35%) of non-Celts and 88 (50%) of Celts were aged under 40 years. Alcohol dependence (ICD 303) was significantly commoner (p<0.001) among the Celts (35.3%) than among the non-Celts (12.9%). There were highly significant excesses (p<0.001) of native-born Celts with ICD 303 (54%) compared with non-Celts 12.9% or with Celts born outside Celtdom (23%). Patients with Norman names tended to follow the Celts in these respects. There were no differences with respect to the prevalence of psychosis or other ICD categories among Celts and non-Celts.Conclusion: Doctors should be aware of the high prevalence of alcoholic dependence among people with Celtic names, whether these were born in Celtic countries or not, entertain a high index of diagnostic suspicion and take preventative measures accordingly. However, we found no excess of other categories of psychiatric disorder among Celts as compared with non-Celts. Patients with Norman-derived names seemed to follow the Celts in these respects.
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Tesi sul tema "Alcoholism – Diagnosis"

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Proudfoot, Heather Public Health &amp Community Medicine Faculty of Medicine UNSW. "DSM-IV alcohol use disorders in Australia: validity, prevalence and treatment seeking". Awarded by:University of New South Wales. School of Public Health and Community Medicine, 2006. http://handle.unsw.edu.au/1959.4/26323.

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Alcohol use disorders are common and make a significant contribution to the burden of disease throughout the world. This is especially true among the younger age groups. Although these disorders are common, evidence suggests that those affected do not seek help for their disorders. In order to understand this, reviews of the treatment literature and the epidemiological data on prevalence and correlates of alcohol use disorders and treatment seeking are presented. These reviews confirm that effective treatments exist and that screening in primary care can be efficacious. The reviews also highlight deficits such as the need for more epidemiological evidence on the validity of DSM definitions of alcohol use disorders and for more Australian data on the prevalence and correlates of the disorders and related treatment seeking. This thesis sets out to address these deficits applying sophisticated statistical techniques to data from a large nationally representative Australian sample. A confirmatory factor analysis of the eleven criteria that specify alcohol dependence and abuse examined the validity of DSM-IV definitions of alcohol use disorders and the best solution was found to be a single factor, not two as currently defined. These findings question the bi-axial nature of alcohol use disorders that has underpinned their definition since the publication of DSM-III-R in 1987. Data from this national sample also confirm that, in line with research from other western countries, Australians have high levels of alcohol use disorders, especially amongst males and younger people. Also no association was found between alcohol dependence and treatment seeking, and young people were least likely to seek treatment. However, a relatively large proportion of young people who drink had been in contact with their GPs in the past year; demonstrating that there is ample opportunity for screening and referral for treatment for alcohol use disorders in this vulnerable group. This research has found that although alcohol disorders are not necessarily associated with disability, there are those who can benefit from treatment. It suggests that outcomes for such individuals may be improved by better specification of disorders as well as improved access to best treatments.
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Koopman, Fred Andrew. "An assessment of the perception and practices of general practitioners (GPs) in Cape Town regarding problem drinking amongst their patients". Thesis, University of the Western Cape, 2005. http://etd.uwc.ac.za/index.php?module=etd&action=viewtitle&id=init_7441_1180442576.

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Since the anecdotal assumption is that GPs do not effectively diagnose and manage problem drinking amongst their patients, this study investigated the role of GPs in addressing problem drinking in Cape Town as well as the prevalence of problem drinking amongst their patients.

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Klikunas, Wojciech. "Construct validity of the Substance Abuse Subtle Screening Inventory (SASSI) as a screening instrument for alcoholism". Virtual Press, 1988. http://liblink.bsu.edu/uhtbin/catkey/546154.

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The purpose of the study was to evaluate the construct validity of the Substance Abuse Subtle Screening Inventory (SASSI) as a screening test for alcoholism. The study sample consisted of 238 participants. These included 50 alcoholics, 50 normals, 50 psychiatric outpatients, 50 co-dependent family members and 38 drug addicts, so classified by clinician diagnosis.All participants were administered the SASSI and also the Michigan Alcoholism Screening Test (MAST) and the MacAndrew Alcoholism-Screening Scale (AMAC). Correct classification rates for all three tests were determined using both a five-group criterion of classifying as an alcoholic, normal, psychiatric outpatient, co-dependent or drug addict, and a simpler two-group criterion of classifying as a substance abuser or non-abuser. Five null hypotheses were tested using Chi-square (alpha = .01) tests for equal proportions of classification accuracy. A sixth null hypothesis was tested using linear discriminant function analyses.Results Five-group criterion:1. The three tests differed in correctly classifying alcoholics, with the MAST statistically significantly superior to the AMAC and the SASSI.2. The three tests differed in correctly classifying normals, with the MAST and the AMAC statistically significantly superior to the SASSI.3. The three tests differed in correctly classifying psychiatric outpatients, with the AMAC statistically significantly superior to the SASSI.4. The three tests differed in correctly classifying drug addicts, with the AMAC and the SASSI statistically significantly superior to the MAST.5. The three tests did not differ to a statistically significant degree in classifying codependents.Two-group criterion (abuser/non-abuser):1. The three tests differed in correctly classifying alcoholics, with the MAST statitically significantly superior to the AMAC and the SASSI.2. The three tests differed in correctly classifying normals, with the SASSI statistically significantly superior to the AMAC and the MAST.3. The three tests differed in correctly classifying psychiatric outpatients, with the SASSI and the AMAC statistically significantly superior to the MAST.4. The three tests differed in correctly classifying drug addicts, with the MAST statistically significantly superior to the AMAC and the SASSI.5. The three tests differed in correctly classifying co-dependents, with the SASSI statistically significantly superior to the AMAC and the MAST.Employing the two-group criterion, all tests vastly improved their performance with the SASSI significantly superior to the MAST and the AMAC at author-recommended cutting scores. Increasing the cutting score for the MAST improved classification accuracy even further. Employing the linear discriminant function, the three tests differed significantly, with the MAST statistically significantly superior to all other scales.ConclusionsNone of the three scales performed adequately with the five-group criterion. The simpler two-group criterion produced an 87% classification accuracy rate for the SASSI with the study sample at author-recommended cutting scores, which was statistically significantly superior to the MAST and the AMAC. The highest classification accuracy rates of 90.3% and 91.2% respectively were produced by the MAST at elevated cutting scores of 10 and 12 in the two-group criterion. These parallelled linear discriminant function results for the MAST.
Department of Counseling Psychology and Guidance Services
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Mangueira, Suzana de Oliveira. "RevisÃo do diagnÃstico de enfermagem processos familiares disfuncionais relacionados a abuso de Ãlcool". Universidade Federal do CearÃ, 2014. http://www.teses.ufc.br/tde_busca/arquivo.php?codArquivo=11952.

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FundaÃÃo de Amparo a CiÃncia e Tecnologia de Pernambuco
O estudo tem como objeto a revisÃo do diagnÃstico de enfermagem Processos familiares disfuncionais relacionados a abuso de Ãlcool. Estudo metodolÃgico, desenvolvido em trÃs etapas: anÃlise de conceito, anÃlise de conteÃdo por especialistas e anÃlise da acurÃcia de indicadores clÃnicos. Para a realizaÃÃo da anÃlise de conceito, utilizou-se como referÃncia o modelo de anÃlise de conceito proposto por Walker e Avant e os passos da revisÃo integrativa da literatura. Procedeu-se à busca na literatura em trÃs bases de dados: SCOPUS, PubMed e CINAHL, com os descritores alcoolismo e famÃlia disfuncional e suas sinonÃmias nas lÃnguas inglesa e espanhola. ApÃs a aplicaÃÃo dos critÃrios de inclusÃo e exclusÃo, restaram 11 estudos de um total de 113 que subsidiaram a anÃlise do conceito. A partir da revisÃo do conceito famÃlia disfuncional e sua correlaÃÃo com o diagnÃstico de enfermagem Processos familiares disfuncionais, foi possÃvel reduzir o quantitativo de 115 caracterÃsticas definidoras para 91, por meio da exclusÃo de 24 caracterÃsticas que apresentaram significado semelhante a outros indicadores ou por nÃo se aplicarem a alcoolistas adultos. TrÃs caracterÃsticas foram condensadas em uma e foram incorporadas duas novas caracterÃsticas definidoras: abuso fÃsico e abuso sexual. Foram utilizados artigos, livros e dicionÃrios para a construÃÃo das definiÃÃes conceituais e operacionais das 91 caracterÃsticas definidoras. A segunda etapa do estudo, anÃlise de conteÃdo por especialistas, consistiu no julgamento por 23 especialistas quanto à relevÃncia, clareza e precisÃo das definiÃÃes construÃdas na etapa anterior. Dois itens foram julgados como inadequados no critÃrio relevÃncia e, portanto, excluÃdos do estudo. Dezessete itens tiveram suas definiÃÃes julgadas como inadequadas nos critÃrios clareza e/ou precisÃo e foram reformuladas. Duas caracterÃsticas tiveram seu rÃtulo modificado segundo sugestÃes dos especialistas. Para esta etapa, considerou-se o nÃvel de concordÃncia de 85%. A partir das definiÃÃes operacionais das 89 caracterÃsticas definidoras julgadas como relevantes pelos especialistas, foi construÃdo o instrumento de coleta de dados aplicado com 110 alcoolistas internados em uma unidade de cuidados prolongados para tratamento de alcoolismo crÃnico. Para a delimitaÃÃo da amostra, foi realizado cÃlculo amostral e estabelecidos critÃrios de inclusÃo e exclusÃo. Os dados foram coletados por meio de entrevista e analisou-se a presenÃa ou ausÃncia de cada indicador clinico. Os dados foram submetidos à anÃlise de classe latente, que permitiu encontrar um conjunto de vinte e quatro caracterÃsticas que apresentaram bom ajuste para a correta identificaÃÃo do diagnÃstico Processos familiares disfuncionais. As caracterÃsticas definidoras Papeis familiares interrompidos, Problemas econÃmicos e Rituais familiares interrompidos apresentaram boa sensibilidade e especificidade. As caracterÃsticas definidoras Abuso sexual, DistÃrbio no desempenho escolar em crianÃas, ManipulaÃÃo, Falta de coesÃo e Baixa autoestima crÃnica apresentaram valor de especificidade significativo. As demais mostraram valor de sensibilidade significativo: Mentiras, AngÃstia, Ansiedade, ConfusÃo, Constrangimento, Perda, Raiva, ComunicaÃÃo contraditÃria, Dificuldade com relacionamentos Ãntimos, Imaturidade, Tristeza nÃo resolvida, DeterioraÃÃo nos relacionamentos familiares, DinÃmicas familiares perturbadas, Problemas conjugais, InseguranÃa e SolidÃo. A revisÃo do diagnÃstico Processos familiares disfuncionais relacionados a abuso de Ãlcool possibilitou uma reflexÃo crÃtica acerca das caracterÃsticas definidoras constantes na NANDA-I, com vistas ao seu refinamento. Espera-se que este estudo possa auxiliar o enfermeiro na sua prÃtica assistencial a identificar o referido diagnÃstico de modo mais acurado.
The study focuses the review of the nursing diagnosis Dysfunctional family processes related to alcohol abuse. Methodological study, developed in three stages: concept analysis, content analysis by experts and analysis of the accuracy of clinical indicators. For the realization concept analysis, was used as reference the concept analysis model proposed by Walker and Avant and steps of the integrative literature review. Proceeded the literature search in three databases: SCOPUS, PubMed and CINAHL, with descriptors alcoholism and dysfunctional family and their synonyms in English and Spanish. After applying the inclusion and exclusion criteria, 11 studies remained from a total of 113 that supported the concept analysis. From the review of the concept dysfunctional family and its correlation with the nursing diagnosis of Dysfunctional family processes, it was possible to reduce the quantitative defining characteristics from 115 to 91, by deleting the 24 characteristics that were similar to other indicators or meaning is not apply to adult alcoholics. Three characteristics were condensed into one and were incorporated two new defining characteristics: Physical abuse and Sexual abuse. Articles, books and dictionaries were used to build the conceptual and operational definitions of the 91 defining characteristics. The second stage of the study, content analysis by experts consisted at trial of 23 experts for relevance, clarity and accuracy of definitions constructed in the previous step. Two items were judged as inappropriate in relevance criteria and therefore excluded from the study. 17 items had their definitions judged as inadequate on the clarity and/or precision criteria and have been reformulated. Two had their labels modified second suggestions from experts. For this step, was considered the level of agreement of 85 %. From the operational definitions of the 89 defining characteristics judged as relevant by experts, was built the instrument of data collection applied with 110 alcoholics admitted to a unit for extended care treatment of chronic alcoholism. For the delimitation of the sample, sample size calculation was performed and established criteria for inclusion and exclusion. Data were collected through interviews and analyzed for the presence or absence of each clinical indicator. The data were subjected to latent class analysis, which allowed to find a set of twenty-four characteristics that showed good fit for the correct identification of diagnostic Dysfunctional family processes. The defining characteristics Disrupted family roles, Economic problems and Disrupted family rituals showed good sensitivity and specificity. The defining characteristics Sexual abuse, Disturbances in academic performance in children, Manipulation, Lack of cohesiveness and Chronic low self-esteem showed the mean value of specificity. The other showed the mean value of sensitivity: Lying, Distress, Anxiety, Confusion, Embarrassment, Loss, Anger, Contradictory communication, Difficulty with intimate relationships, Immaturity, Complicated grieving, Deterioration in family relationships, Disturbed family dynamics, Marital problems, Insecurity and Loneliness.. A review of the diagnosis Dysfunctional family processes related to alcohol abuse provided a critical analysis of the defining characteristics listed in the NANDA-I, with a view to its refinement. It is hoped that this study can help nurses in healthcare practice to identify the diagnosis more accurately.
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Flores, Guadalupe Leon Gomez. "Dually diagnosed mental health clients: A comparative study of those receiving treatment in a dual diagnosis program and those receiving only mental health treatment". CSUSB ScholarWorks, 1997. https://scholarworks.lib.csusb.edu/etd-project/1297.

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Stone, Joseph B. "The Prevalence of Dual Diagnosis of Generalized Anxiety Disorder and Alcoholism in the Literature: A Critical Meta-Analytic Review". DigitalCommons@USU, 1993. https://digitalcommons.usu.edu/etd/6058.

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The relationship between alcoholism and generalized anxiety disorder (GAD) has been discussed in two research areas: research on the prevalence of GAD in alcoholics, and the prevalence of alcoholism in individuals diagnosed with GAD. Studies indicate that between 6 to 26% of alcoholics have a current diagnosis of GAD, with a lifetime prevalence rate of up 51%. In the general population, 4% would currently receive a diagnosis of GAD, with a lifetime prevalence of 8%. This meta-analytic review of the empirical literature examines the relationship between GAD and alcoholism. The author used percentages to compare the results of various studies. The averaged results of these various studies suggested there is a 25% comorbidity rate of GAD and alcoholism. critical review of the studies examined in this review revealed substantial methodological errors. Based on a critical review of the research methodology in the studies cited, the author proposed further research.
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Escher, Furtado Luísa. "Le sujet alcoolique : l'articulation entre diagnostic, nomination et identité". Thesis, Strasbourg, 2017. http://www.theses.fr/2017STRAG019/document.

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L’analyse de l'arrimage de l'alcoolisme à la construction du sujet et la manière dont le diagnostic alcoolique peut produire des effets sur l’identité, nous a amené a élaborer trois hypothèses : l'étiquette 'alcoolique' peut avoir des effets dans le processus de production de la subjectivité; les effets subjectifs de la nomination sont liées aux usages que le nom« alcoolique » a dans de différents contextes historiques ; l'identification comme alcoolique est marquée par une recherche d’alliance du sujet à un réseau social plutôt que par le sentiment d'identité subjectif d'uniformité et de continuité de ce que désigne le diagnostic d'alcoolisme. La recherche de terrain dans des Centres d’addictologie et des Associations a abouti à la réalisation de cinq entretiens. L'identité alcoolique peut constituer des processus d'appartenance pour qui a une vie marquée par la migration; de résistance au productivisme, pour qui a dû travailler à l’armée et sur des chaînes de production; et une ouverture à l'amitié pour qui a souffert de ruptures affectives. Cependant cette identité peut cacher la singularité du sujet, lorsqu’elle sert comme explication close et clé à des conflits
The analysis of the connection made of alcoholism to the construction of the subject and how the alcoholic diagnosis might produce effects on the process of production of identity lead us to three hypotheses: the label "alcoholic" might impact the process of production of subjectivity; the subjective effects of a nomination are related to the uses the name “alcoholic” have in different historical contexts; The identification as an alcoholic is marked by a search for alliance of the subject with a social network a lot more than it is marked for the subjective feeling of identity to a uniformity and continuing of what is designated by the diagnosis of alcoholism. The field research in addictology centres and associations derived from five interviews. The alcoholic identity might constitute a process of belonging for those who have their lives transformed by migration; of resisting productivism, for those who have to be in the army and in big productive chains and it could also be an opening to new friendships for those who have been through relationship break-ups. However, this identity might hide the singularity of the subject, as when it is used as a conclusive key explanation to conflicts
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Magnani, Karla Luciana. "Estudo morfo-funcional, bioquímico e imunohistoquíco do aparelho respiratório em ratos expostos à fumaça do cigarro e ao álcool /". Botucatu, 2009. http://hdl.handle.net/11449/99890.

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Abstract (sommario):
Resumo: Visto que 80-95% dos estilistas são também tabagistas, é desejável que modelos experimentais de estudo dos efeitos deletérios do consumo crônico do álcool incluam grupos com a associação de etilismo e tabagismo, permitindo desta forma, mimetizar, de maneira mais precisa, os efeitos do abuso crônico do álcool em humanos. Objetivo: Investigar os efeitos da exposição crônica à fumaça do cigarro e ao álcool no estresse oxidativo, nas alterações morfo-funcionais e distúrbios imunohistoquímicos provocados por estas agressões no aparelho respiratório de ratos. Método: cento e vinte ratos machos Wistar foram divididos em oito subgrupos de quinze animais (controle, tabagista, alcoolista e alcoolista + tabagista) em dois tempos experimentais (180 e 260 dias). Os biomarcadores de estresse oxidativo (superóxido dismutase, concentração da proteína tiol, glutationa perodixase e substâncias reativas ao ácido tiobarbitúrico) foram pesquisados em hemáceas lavadas. As alterações morfo-funcionais pulmonares (presença de reação inflamatória e estimativa de enfisema) foram avaliadas através do estudo histológico em microscopia óptica e estudo do pulmão isolado (complacência e complacência específica). O estudo imunohistoquímico foi realizado através da pesquisa da expressão de survivina, proteína P53, antígeno nuclear de proliferação celular e do índice apoptótico, pela técnica de TUNEL, no parênquima pulmonar e na traquéia. Resultados: o peso corpóreo dos três grupos experimentais foi menor que o grupo controle, sendo os menores valores os dos grupos alcoolista + tabagista, sendo a estimativa de enfisema pulmonar também maior nestes animais. Os animais dos grupos tabagistas e tabagistas + alcoolista apresentaram: menor complacência, maior incidência de bronquiolite, maior expressão para a survivina nas traqueias e maior índice apoptótico... (Resumo completo, clicar acesso eletrônico abaixo)
Abstract: Since 80-95% of alcoholic are also smokers, it is desirable that study's experimental models of deleterious effects of chronic alcohol consumption includes groups with association of alcohol and tobacco, thus allowing, mimic, more accurately, the effects of chronic alcohol abuse in humans. Objective: To investigate the effects of chronic exposure to cigarette smoke and alcohol on oxidative stress, on morpho-functional alterations and immunohistochemical disorders caused by these attacks to respiratory system of rats. Method: one hundred and twenty Wistar rats were divided into eight subgroups of fifteen animals (control, smoking, alcohol and alcohol + smoking) in two experimental times (180 and 260 days). Biomarkers of oxidative stress (superoxide dismutase, tiol protein concentration, glutathione perodixase and thiobarbituric acid reactive substances) were determined in washed red cells. The morpho-functional lung's alterations (presence of inflammatory reaction and estimate of emphysema) were evaluated by histological examination with optical microscopy and study of the isolated lung (compliance and specific compliance). The immunohistochemistry study was performed by investigating the expression of survivin, P53 protein, nuclear antigen of cell proliferation and apoptotic index by TUNEL technique, at pulmonary parenchyma and trachea. Results: The weight of the three experimental groups was lower than the control group, with the lowest values at the alcoholism + smoking groups, and the estimated pulmonary emphysema was higher also in these animals. The smokers and smokers+alcoholic groups's animals showed: lower compliance, higher incidence of bronchiolitis, larger survivin expression to trachea and higher bronchiolar apoptotic index. Animals exposed only to smoking showed elevated levels of thiobarbituric acid reactive substances and lower specific compliance. The three... (Complete abstract click electronic access below)
Orientador: Antonio José Maria Cataneo
Coorientador: Daniele Cristina Cataneo
Banca: Débora Damasceno
Banca: Maria Aparecida Custódio Domingues
Banca: Vera Luzia Capelozzi
Doutor
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Hester, Amanda Spicer. "Juror perceptions of a woman who killed her abusive husband effects of wife's psychological diagnosis, husband's history of alcoholism, and documentation of domestic violence /". Master's thesis, Mississippi State : Mississippi State University, 2009. http://library.msstate.edu/etd/show.asp?etd=etd-04012009-164826.

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Hester, Amanda Spicer. "JUROR PERCEPTIONS OF A WOMAN WHO KILLED HER ABUSIVE HUSBAND: EFFECTS OF WIFES PSYCHOLOGICAL DIAGNOSIS, HUSBANDS HISTORY OF ALCOHOLISM, AND DOCUMENTATION OF DOMESTIC VIOLENCE". MSSTATE, 2009. http://sun.library.msstate.edu/ETD-db/theses/available/etd-04012009-164826/.

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Abstract (sommario):
This study examined about 500 mock juror perceptions in a murder trial in which the defendant claims to have killed her abusive husband in self-defense. The defendants psychological diagnosis, the husbands alcohol abuse history, and documentation of domestic violence were varied across conditions. Results showed that medical evidence of domestic violence had a significant effect on guilt ratings and on perceptions of blame for the husbands death. History of alcohol use of the husband influenced mock jurors perceptions of the credibility of the defendant. Juror gender effects were also found on verdict ratings. In contrast, no main effect was found for the defendants diagnosis.
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Libri sul tema "Alcoholism – Diagnosis"

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The diagnosis and treatment of alcoholism. 2a ed. Northvale, N.J: J. Aronson, 1994.

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Cornel, Michiel. Detection of problem drinkers in general practice. Amsterdam: Thesis Publishers, 1994.

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Cornel, Michiel. Detection of problem drinkers in general practice. Roterdam: STIVA, 1994.

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Gallant, Donald M. Alcoholism: A guide to diagnosis, intervention, and treatment. New York: Norton, 1987.

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Alcohol problems: Diagnosis and treatment. New York: Pergamon Press, 1986.

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Hennigan, Leo P. A conspiracy of silence: Alcoholism. Bethesda, Md: Gannell Publications, 1989.

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Beasley, Joseph D. Wrong diagnosis, wrong treatment: The plight of the alcoholic in America. Durant, OK: Creative Infomatics, 1987.

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Identification and treatment of alcohol dependency. Keswick, Cumbria: M&K Update, 2008.

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Qin ai de bie zui liao: Jie shi jiu yu shen xin jian kang guan xi. Haikou Shi: Nan hai chu ban she, 2008.

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Association des intervenants en toxicomanie du Québec. Colloque. L' évaluation de la clientèle ; Les enfants adultes d'alcooliques. [Montréal]: AITQ, 1989.

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Capitoli di libri sul tema "Alcoholism – Diagnosis"

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Savitsky, Joan. "Early Diagnosis and Screening". In Alcoholism, 47–58. New York, NY: Springer New York, 1987. http://dx.doi.org/10.1007/978-1-4612-4786-9_5.

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Barnes, Henrietta N. "Presenting the Diagnosis: Working with Denial". In Alcoholism, 59–65. New York, NY: Springer New York, 1987. http://dx.doi.org/10.1007/978-1-4612-4786-9_6.

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Miller, Norman S., e Mark S. Gold. "Clinical Diagnosis of Alcoholism". In Alcohol, 83–94. Boston, MA: Springer US, 1991. http://dx.doi.org/10.1007/978-1-4899-3550-2_7.

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Feuerlein, Wilhelm. "Diagnosis of Alcoholism — Introductory Remarks". In Psychiatry, 29. Boston, MA: Springer US, 1985. http://dx.doi.org/10.1007/978-1-4613-2365-5_5.

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Schmidt, L. G. "Alcoholism: Aetiology, Epidemiology and Diagnosis". In Contemporary Psychiatry, 2097–110. Berlin, Heidelberg: Springer Berlin Heidelberg, 2001. http://dx.doi.org/10.1007/978-3-642-59519-6_134.

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McKenna, Alina M., e Alfonso Paredes. "Dual-Diagnosis Empirical and Developmental-Humanistic Approaches". In Recent Developments in Alcoholism, 89–107. Boston, MA: Springer US, 1992. http://dx.doi.org/10.1007/978-1-4899-1648-8_5.

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Miller, Norman S., e Mark S. Gold. "Laboratory Diagnosis of Alcoholism and Drug Addiction". In Alcohol, 95–111. Boston, MA: Springer US, 1991. http://dx.doi.org/10.1007/978-1-4899-3550-2_8.

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Miller, Norman S., e Mark S. Gold. "Diagnosis of Psychiatric Syndromes in Alcoholism and Drug Addiction". In Alcohol, 113–30. Boston, MA: Springer US, 1991. http://dx.doi.org/10.1007/978-1-4899-3550-2_9.

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De Martin, Martina, Francesca Pecori Giraldi e Francesco Cavagnini. "Laboratorial Diagnosis of Cushing’s Syndrome: Differential Diagnosis with Pseudo Cushing’s Conditions as Obesity, Alcoholism and Depression". In Cushing's Syndrome, 65–78. Totowa, NJ: Humana Press, 2010. http://dx.doi.org/10.1007/978-1-60327-449-4_6.

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Seixas, Frank A. "The NCA Criteria for the Diagnosis of Alcoholism-Intent, Use, and Practicality". In Psychiatry, 71–79. Boston, MA: Springer US, 1985. http://dx.doi.org/10.1007/978-1-4613-2365-5_12.

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Atti di convegni sul tema "Alcoholism – Diagnosis"

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Upadhyay, R., P. K. Padhy e P. K. Kankar. "Alcoholism diagnosis from EEG signals using continuous wavelet transform". In 2014 Annual IEEE India Conference (INDICON). IEEE, 2014. http://dx.doi.org/10.1109/indicon.2014.7030476.

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Yu, Yang, Jeon Woong Kang, Zhi Yang Tam, Shuo Yu Xu, Eliza Li Shan Fong, Surya Pratap Singh, Ziwei Song et al. "A classification model for non-alcoholic steatohepatitis (NASH) using confocal Raman micro-spectroscopy". In Clinical and Preclinical Optical Diagnostics, a cura di J. Quincy Brown e Ton G. van Leeuwen. SPIE, 2017. http://dx.doi.org/10.1117/12.2281445.

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Choi, Changhoon, Wonseok Choi, Jeesu Kim e Chulhong Kim. "Photothermal strain imaging for diagnosis of non-alcoholic fatty liver disease". In Photons Plus Ultrasound: Imaging and Sensing 2020, a cura di Alexander A. Oraevsky e Lihong V. Wang. SPIE, 2020. http://dx.doi.org/10.1117/12.2544552.

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Byrne, CD. "4 Diagnosis and management of non-alcoholic fatty liver disease (NAFLD)". In Abstracts from the Fellowship of Postgraduate Medicine Centenary Conference 2018: Transforming Health and Health Care. The Fellowship of Postgraduate Medicine, 2018. http://dx.doi.org/10.1136/postgradmedj-2018-fpm.4.

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Benjamin, Alex, Rebecca Zubajlo, Kai Thomenius, Manish Dhyani, Kanakaraju Kaliannan, Anthony E. Samir e Brian W. Anthony. "Non-invasive diagnosis of non-alcoholic fatty liver disease (NAFLD) using ultrasound image echogenicity". In 2017 39th Annual International Conference of the IEEE Engineering in Medicine and Biology Society (EMBC). IEEE, 2017. http://dx.doi.org/10.1109/embc.2017.8037468.

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Gyorfi, Nina, Akos Odry, Zoltan Karadi, Peter Odry, Tibor Szakall, Bojan Kuljic, Attila Toth e Zoltan Vizvari. "Development of Bioimpedance-based Measuring Systems for Diagnosis of Non-alcoholic Fatty Liver Disease". In 2021 IEEE 15th International Symposium on Applied Computational Intelligence and Informatics (SACI). IEEE, 2021. http://dx.doi.org/10.1109/saci51354.2021.9465584.

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Lemmer, P., N. Selbach, T. Baars, A. Canbay e JP Sowa. "Serum concentrations of classic liver enzymes are unsuitable for diagnosing non-alcoholic steatohepatitis". In 37. Jahrestagung der Deutschen Arbeitsgemeinschaft zum Studium der Leber. Georg Thieme Verlag KG, 2021. http://dx.doi.org/10.1055/s-0040-1721952.

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Grigorescu, M., C. Radu, M. Lupsor, C. Vicas, S. Nedevschi, R. Badea, Z. Sparchez, D. Crisan e Al Serban. "Comparison between attenuation coefficient computed on the ultrasound image and a biological marker, adiponectin, in the diagnosis of steatosis in non-alcoholic fatty liver disease". In 2008 IEEE International Conference on Automation, Quality and Testing, Robotics (AQTR 2008). IEEE, 2008. http://dx.doi.org/10.1109/aqtr.2008.4588894.

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Karachevtsev, Artem, V. Prysyazhnyuk, Vladimir Ushenko, Alexander Ushenko e M. Slyotov. "Stokes polarimetric reproductions of the degree of crystallization of blood plasma films in the diagnosis and differentiation of non-alcoholic fatty liver disease and chronic hepatitis". In Fourteenth International Conference on Correlation Optics, a cura di Oleg V. Angelsky. SPIE, 2020. http://dx.doi.org/10.1117/12.2553958.

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Radu, C., M. Grigorescu, M. Lupsor, C. Vicas, S. Nedevschi, R. Badea, M. D. Grigorescu, Z. Sparchez, D. Crisan e D. Feier. "The diagnostic performance of attenuation coefficient computed on the ultrasound image compared to a biochemical marker — SteatoTest — for steatosis quantification in non-alcoholic fatty liver disease". In 2010 IEEE International Conference on Automation, Quality and Testing, Robotics (AQTR 2010). IEEE, 2010. http://dx.doi.org/10.1109/aqtr.2010.5520717.

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