Letteratura scientifica selezionata sul tema "Active medical implants"
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Articoli di riviste sul tema "Active medical implants":
1
Kim, Juho, Jimin Seo, Dongwuk Jung, Taeyeon Lee, Hunpyo Ju, Junkyu Han, Namyun Kim et al. "Active photonic wireless power transfer into live tissues". Proceedings of the National Academy of Sciences 117, n. 29 (6 luglio 2020): 16856–63. http://dx.doi.org/10.1073/pnas.2002201117.
Abstract (sommario):
Recent advances in soft materials and mechanics activate development of many new types of electrical medical implants. Electronic implants that provide exceptional functions, however, usually require more electrical power, resulting in shorter period of usages although many approaches have been suggested to harvest electrical power in human bodies by resolving the issues related to power density, biocompatibility, tissue damage, and others. Here, we report an active photonic power transfer approach at the level of a full system to secure sustainable electrical power in human bodies. The active photonic power transfer system consists of a pair of the skin-attachable photon source patch and the photovoltaic device array integrated in a flexible medical implant. The skin-attachable patch actively emits photons that can penetrate through live tissues to be captured by the photovoltaic devices in a medical implant. The wireless power transfer system is very simple, e.g., active power transfer in direct current (DC) to DC without extra circuits, and can be used for implantable medical electronics regardless of weather, covering by clothes, in indoor or outdoor at day and night. We demonstrate feasibility of the approach by presenting thermal and mechanical compatibility with soft live tissues while generating enough electrical power in live bodies throughin vivoanimal experiments. We expect that the results enable long-term use of currently available implants in addition to accelerating emerging types of electrical implants that require higher power to provide diverse convenient diagnostic and therapeutic functions in human bodies.
2
Wychowański, Piotr, Anna Starzyńska, Paulina Adamska, Monika Słupecka-Ziemilska, Bartosz Kamil Sobocki, Agnieszka Chmielewska, Bartłomiej Wysocki et al. "Methods of Topical Administration of Drugs and Biological Active Substances for Dental Implants—A Narrative Review". Antibiotics 10, n. 8 (28 luglio 2021): 919. http://dx.doi.org/10.3390/antibiotics10080919.
Abstract (sommario):
Dental implants are, nowadays, established surgical devices for the restoration of lost teeth. Considered as an alternative for traditional prosthetic appliances, dental implants surpass them in reliability and patient feedback. Local drug delivery around the implants promotes osseointegration and reduces peri-implantitis. However, there are currently no methods of a multiple, precise topical administration of drugs to the implant area. Engineering coatings on the implants, drug application on carriers during implantation, or gingival pockets do not meet all requirements of dental surgeons. Therefore, there is a need to create porous implants and other medical devices that will allow a multiple drug delivery at a controlled dose and release profile without traumatic treatment. Due to the growing demand for the use of biologically active agents to support dental implant treatment at its various stages (implant placement, long-term use of dental superstructures, treatment of the peri-implant conditions) and due to the proven effectiveness of the topical application of pharmacological biologically active agents to the implant area, the authors would like to present a review and show the methods and devices that can be used by clinicians for local drug administration to facilitate dental implant treatment. Our review concludes that there is a need for research in the field of inventions such as new medical devices or implants with gradient solid–porous structures. These devices, in the future, will enable to perform repeatable, controllable, atraumatic, and repeatable injections of active factors that may affect the improvement of osteointegration and the longer survival of implants, as well as the treatment of peri-implantitis.
3
Awaja, Firas, e Shengnan Zhang. "Self-bonding of PEEK for active medical implants applications". Journal of Adhesion Science and Technology 29, n. 15 (29 aprile 2015): 1593–606. http://dx.doi.org/10.1080/01694243.2015.1037382.
4
Kumar, Raman. "A Bibliometric Analysis and Visualisation of Research Trends in Corrosion of Titanium Implants". Turkish Journal of Computer and Mathematics Education (TURCOMAT) 12, n. 2 (11 aprile 2021): 120–25. http://dx.doi.org/10.17762/turcomat.v12i2.687.
Abstract (sommario):
Corrosion of medical implants is a serious issue in the medical sector. The bibliometric analysis had been conducted to understand the active authors, organizations, journals, and countries involved in the research domain of “corrosion of Titanium implants”. All published articles related to “corrosion of Titanium implants” from “Scopus”, were analyzed using the VOS viewer to develop analysis tables and visualization maps. This article had set the objective to consolidate the scientific literature regarding “corrosion of Titanium implants” and also to find out the trends related to the same. The most active journals in this research domain were Material Science and Engineering C and Biomaterials. The most active country was the United States of America. The leading organizations engaged in the research regarding the Corrosion of Titanium implants were the Sao Paulo State University of Brazil. The most active authors who had made valuable contributions related to corrosion of Titanium implants were Jacob J.J and Zhang X.
5
Suresh, Ganzi, K. L Narayana e M. Kedar Mallik. "Bio-Compatible Processing of LENSTM DepositedCo-Cr-W alloy for Medical Applications". International Journal of Engineering & Technology 7, n. 2.20 (18 aprile 2018): 362. http://dx.doi.org/10.14419/ijet.v7i2.20.16734.
Abstract (sommario):
Developing a Medicinal implants or devices is a challenging task for the researchers, right from the selection of materials, design, bio-compatibility and implantation to the host tissue. At every stage it requires proper care in processing of medical implants. In recent years the demand for medical implants had grown rapidly due to the awareness in the society. Major share of implants is used by younger people as they are active in sports, motor vehicle accidents leads to facture. Even older people also preferring to implants for ease of living. The commonly used implants are, prosthetic joints, knee replacement, dental, maxillofacial reconstructions etc.There is huge demand for the medical implants in coming years, presently a few bio-materials available for implant devices such as Ti-alloys, Stainless steel and Co-Cr-Mo alloys. There a scope to the researchers to develop a new alloy that are bio-compatible in nature and bring down the cost of the implant procedure to the needed patients. In this context additive manufacturing (AM) is an advanced manufacturing technology emerging as prominent technique in medical fields. Laser Engineered Net ShapingTM (LENS) is one such metal additive technique which provides fabrication of parts with the help of laser power, melts the powder alloy completely and builds parts layer by layer directly from the CAD model.In the present study, samples are fabricated from LENS process and carried the In-Vitro and In -Vivo bio-compatible tests as cytotoxicity and sub chronic toxicity to verify the toxicants release and their sustainability as the medical implants by the LENS deposited Co-Cr-W alloy samples. From the studies it is observed that the alloy samples show acceptable result. MTT assay demonstrate that cell viability is better in Osteoblast cells compared to the Fibroblast cells. Osteoblast cells show slightly more viable to the cell treatment on the samples during the experimental period. Sub chronic toxicity conclude that LENS deposited Co-Cr-W alloy is not toxic in all the rats studied herein and did not produce any toxic signs or evident symptoms. LENS deposited Co-Cr-W alloy did not cause any lethality or produce any relative body organs weight and haematological studies didn’t show adverse effects.
6
Gill, Harjot Singh. "A Bibliometric Analysis and Visualisation of Research Trends in Corrosion of Cobalt-Implants". Turkish Journal of Computer and Mathematics Education (TURCOMAT) 12, n. 2 (11 aprile 2021): 86–91. http://dx.doi.org/10.17762/turcomat.v12i2.681.
Abstract (sommario):
Cobalt is one of the most used metals for implants. The bibliometric analysis had been conducted to understand the active authors, organizations, journals, and countries involved in the research domain of “Corrosion of Cobalt-implants”. All published articles related to “Corrosion of Cobalt-implants” from “Scopus”, were analyzed using the VOS viewer to develop analysis tables and visualization maps. This article had set the objective to consolidate the scientific literature regarding “Corrosion of Cobalt-implants” and also to find out the trends related to the same. The most active journal in this research domain was the Journal of Biomedical Materials Research. The most active country was the United States of America. The leading organization engaged in the research regarding corrosion of Cobalt-implants was the Rush University Medical Center, USA. The most active authors who had made valuable contributions related to Cobalt implants were Hart A.J and Joseph J. J
7
Thind, Gurpreet. "A Bibliometric Analysis and Visualisation of Research Trends in Toxicity of Nickel-implants". Turkish Journal of Computer and Mathematics Education (TURCOMAT) 12, n. 2 (11 aprile 2021): 75–80. http://dx.doi.org/10.17762/turcomat.v12i2.679.
Abstract (sommario):
Nickel is one of the most used metals for implants. The bibliometric analysis had been conducted to understand the active authors, organizations, journals, and countries involved in the research domain of “Toxicity of Nickel-implants”. All published articles related to “Toxicity of Nickel-implants” from “Scopus”, were analyzed using the VOS viewer to develop analysis tables and visualization maps. This article had set the objective to consolidate the scientific literature regarding “Toxicity of Nickel-implants” and also to find out the trends related to the same. The most active journals in this research domain biomaterial. The most active country was the United States of America and United Kingdom. The leading organization engaged in the research regarding the toxicity of Nickel implants was the Rush University Medical Center, United States of America. The most active author who had made valuable contributions related to the toxicity of Nickel implants was Hallab N.J.
8
Singh, Sandeep. "A Bibliometric Analysis and Visualisation of Research Trends in Cobalt-Based Orthopaedic Implants". Turkish Journal of Computer and Mathematics Education (TURCOMAT) 12, n. 2 (11 aprile 2021): 159–63. http://dx.doi.org/10.17762/turcomat.v12i2.695.
Abstract (sommario):
Cobalt is one of the widely used metal for orthopaedic implants. The bibliometric analysis had been conducted to understand the active authors, organizations, journals, and countries involved in the research domain of “Cobalt-based orthopaedic implants”. All published articles related to “Cobalt-based orthopaedic implants” from “Scopus”, were analyzed using the VOS viewer to develop analysis tables and visualization maps. This article had set the objective to consolidate the scientific literature regarding “Cobalt-based orthopaedic implants” and also to find out the trends related to the same. The most active journals in this research domain were the Journal of Orthopaedic Research. The most active country was the United States of America. The leading organization engaged in research regarding Cobalt-based orthopaedic implants was the Rush University Medical Center, United States of America. The most active authors were Hallab N.J.
9
Ramniwas, Seema. "A Bibliometric Analysis and Visualisation of Research Trends in Corrosion of knee implants". Turkish Journal of Computer and Mathematics Education (TURCOMAT) 12, n. 2 (11 aprile 2021): 164–69. http://dx.doi.org/10.17762/turcomat.v12i2.697.
Abstract (sommario):
Corrosion of metals is one of the major challenges of the performance of knee implants. The bibliometric analysis had been conducted to understand the active authors, organizations, journals, and countries involved in the research domain of “Corrosion of knee implants”. All published articles related to “Corrosion of knee implants” from “Scopus”, were analyzed using the VOS viewer to develop analysis tables and visualization maps. This article had set the objective to consolidate the scientific literature regarding “Corrosion of knee implants” and also to find out the trends related to the same. The most active journals in this research domain were the Wear, and Journal of Arthroplasty. The most active countries were the United States of America and India. The leading organizations engaged in the research regarding corrosion of knee-implants were the Drexel University and Rush University Medical Center of United States of America. The most active author related to knee implants was Badar R.
10
Ranjan, Nishant. "A Bibliometric Analysis and Visualisation of Research Trends in Health Issues of Nickel-Implants". Turkish Journal of Computer and Mathematics Education (TURCOMAT) 12, n. 2 (11 aprile 2021): 109–14. http://dx.doi.org/10.17762/turcomat.v12i2.685.
Abstract (sommario):
Nickel toxicity is one of the major challenges of Nickel-based implants. The bibliometric analysis had been conducted to understand the active authors, organizations, journals, and countries involved in the research domain of “Health issues of Nickel-implants”. All published articles related to “Health Issues of Nickel-implants” from “Scopus”, were analyzed using the VOS viewer to develop analysis tables and visualization maps. This article had set the objective to consolidate the scientific literature regarding “Health Issues of Nickel-implants” and also to find out the trends related to the same. The most active journal in this research domain was the Journal of Biomedical Materials Research. The most active country was the United States of America. The leading organization engaged in the research regarding allergy of Nickel-implants was the Rush University Medical Center of United States of America. The most active authors who had made valuable contributions related to the toxicity of Nickel implants were Hallab N.J and Savarino I
Tesi sul tema "Active medical implants":
1
Qu, Zheng. "Biologically active assemblies that attenuate thrombosis on blood-contacting surfaces". Diss., Georgia Institute of Technology, 2012. http://hdl.handle.net/1853/50119.
Abstract (sommario):
All artificial organ systems and medical devices that operate in direct contact with blood elicit activation of coagulation and platelets, and their long-term use often necessitates antithrombotic therapies that carry significant cost and bleeding risk. Thrombomodulin (TM) is a major endogenous inhibitor of blood coagulation localized on the endothelial cell surface. The overall objective of this research is to develop clinically durable synthetic materials by incorporating TM as a solid-supported film to actively and sustainably attenuate thrombus formation at the blood-contacting interface. During the course of this research, we developed site-specific approaches to covalently attach TM on the luminal surface of commercial vascular grafts using bioorthogonal chemistry that was compatible with ethylene oxide sterilization. Notably, we demonstrated the superior efficacy of TM to reduce platelet deposition compared with commercial heparin modified grafts using a non-human primate model of acute graft thrombosis. Finally, we optimized a novel reversible chemistry to rapidly and repeatedly regenerate immobilized TM, with the potential to significantly extend the lifetime of biologically active films.
2
Gercek, Cihan. "Immunité des implants cardiaques actifs aux champs électriques de 50/60 Hz". Thesis, Université de Lorraine, 2016. http://www.theses.fr/2016LORR0226/document.
Abstract (sommario):
La directive européenne 2013/35/UE précise les exigences minimales pour la protection des travailleurs exposés aux champs électromagnétiques et définit les porteurs d’implants comme travailleurs à risques particuliers. Concernant les porteurs de défibrillateur automatique implantable (DAI) ou de stimulateur cardiaque (SC), l’exposition au champ électrique ou magnétique d’extrêmement basse fréquence crée des inductions à l'intérieur du corps humain pouvant générer une tension perturbatrice susceptible de causer le dysfonctionnement de l’implant. Le sujet de ce travail de thèse porte sur la compatibilité électromagnétique des implants cardiaques soumis à un champ électrique basses fréquences (50/60 Hz). Des simulations numériques ont été effectuées afin de concevoir un banc expérimental pour l’exposition de fantômes incluant des stimulateurs ou des défibrillateurs implantables. Une étude expérimentale a permis d’établir par provocation les seuils de champ électrique permettant d’éviter tout dysfonctionnement éventuel de l’implant. Dans la partie simulation numérique ; un modèle humain virtuel (fantôme numérique contenant un implant cardiaque) a été placé en position debout sous une exposition verticale à un champ électrique. La méthode des éléments finis a été utilisée pour définir les phénomènes induits au niveau de l’implant cardiaque avec une résolution de 2mm (logiciel CST®). Dans la partie expérimentale, un banc d'essai dimensionné pour permettre de générer un champ électrique pouvant atteindre 100 kV/m aux fréquences 50-60 Hz a été conçu, optimisé et réalisé afin d’analyser le comportement des implants cardiaques. Plusieurs configurations ont été étudiées. Sur 54 implants cardiaques actifs testés (43 stimulateurs et 11 défibrillateurs) à des niveaux de champs électriques très élevés (100 kV/m) générés par notre dispositif expérimental, aux fréquences de 50-60 Hz, aucune défaillance n’a été observée pour des niveaux d’exposition publics et pour la plupart des configurations (+99%) sauf pour six stimulateurs cardiaques dans le cas d’une configuration « pire cas » peu réaliste en clinique : mode unipolaire avec une sensibilité maximale et en détection auriculaire. Les implants configurés avec une sensibilité nominale en mode bipolaire résistent bien à des champs électriques dépassant les valeurs seuils telles que définies par 2013/UE/35The European Directive 2013/ 35 / EU specify minimum requirements for the protection of workers exposed to electromagnetic fields and define with implants as “workers at particular risk”. Regarding the implantable cardioverter defibrillator wearers (ICD) or pacemaker (PM), exposure to electric or magnetic field of extremely low frequency creates inductions inside the human body that generate interference voltage which may cause the dysfunction of the implant. This thesis investigates the electromagnetic compatibility of cardiac implants subjected to an electric field low frequency (50/60 Hz). Computational simulations are effectuated in order to design an experimental bench for the exposure of a phantom including pacemakers or implantable defibrillators. A provocative study is established to define the electric field thresholds for preventing any malfunction of the implant. In numerical simulations; a virtual human model (digital phantom containing a cardiac implant) was placed in an upright position in a vertical exposure to an electric field. The finite element method was used to define the inductions in the cardiac implant level with a resolution of 2 mm (CST® software). In the experimental part, a test bench designed to allow generating an electric field up to 100 kV / m at frequencies 50-60 Hz was constructed, optimized and employed to investigate the behavior of cardiac implants.Several configurations were studied. 54 active cardiac implants (43 pacemakers and 11 defibrillators) are submitted to very high electric field of 50-60 Hz (up to 100 kV / m) inside the experimental bench. No failure was observed for public exposure levels for most configurations (+ 99%) except for six pacemakers in the case of a configuration clinically almost inexistent: unipolar mode with maximum sensitivity and atrial sensing.The implants configured with a nominal sensitivity in bipolar mode are resistant to electric fields exceeding the low action levels (ALs), even for the most high ALs, as defined by 2013 / 35 / EU
3
Gercek, Cihan. "Immunité des implants cardiaques actifs aux champs électriques de 50/60 Hz". Electronic Thesis or Diss., Université de Lorraine, 2016. http://www.theses.fr/2016LORR0226.
Abstract (sommario):
La directive européenne 2013/35/UE précise les exigences minimales pour la protection des travailleurs exposés aux champs électromagnétiques et définit les porteurs d’implants comme travailleurs à risques particuliers. Concernant les porteurs de défibrillateur automatique implantable (DAI) ou de stimulateur cardiaque (SC), l’exposition au champ électrique ou magnétique d’extrêmement basse fréquence crée des inductions à l'intérieur du corps humain pouvant générer une tension perturbatrice susceptible de causer le dysfonctionnement de l’implant. Le sujet de ce travail de thèse porte sur la compatibilité électromagnétique des implants cardiaques soumis à un champ électrique basses fréquences (50/60 Hz). Des simulations numériques ont été effectuées afin de concevoir un banc expérimental pour l’exposition de fantômes incluant des stimulateurs ou des défibrillateurs implantables. Une étude expérimentale a permis d’établir par provocation les seuils de champ électrique permettant d’éviter tout dysfonctionnement éventuel de l’implant. Dans la partie simulation numérique ; un modèle humain virtuel (fantôme numérique contenant un implant cardiaque) a été placé en position debout sous une exposition verticale à un champ électrique. La méthode des éléments finis a été utilisée pour définir les phénomènes induits au niveau de l’implant cardiaque avec une résolution de 2mm (logiciel CST®). Dans la partie expérimentale, un banc d'essai dimensionné pour permettre de générer un champ électrique pouvant atteindre 100 kV/m aux fréquences 50-60 Hz a été conçu, optimisé et réalisé afin d’analyser le comportement des implants cardiaques. Plusieurs configurations ont été étudiées. Sur 54 implants cardiaques actifs testés (43 stimulateurs et 11 défibrillateurs) à des niveaux de champs électriques très élevés (100 kV/m) générés par notre dispositif expérimental, aux fréquences de 50-60 Hz, aucune défaillance n’a été observée pour des niveaux d’exposition publics et pour la plupart des configurations (+99%) sauf pour six stimulateurs cardiaques dans le cas d’une configuration « pire cas » peu réaliste en clinique : mode unipolaire avec une sensibilité maximale et en détection auriculaire. Les implants configurés avec une sensibilité nominale en mode bipolaire résistent bien à des champs électriques dépassant les valeurs seuils telles que définies par 2013/UE/35The European Directive 2013/ 35 / EU specify minimum requirements for the protection of workers exposed to electromagnetic fields and define with implants as “workers at particular risk”. Regarding the implantable cardioverter defibrillator wearers (ICD) or pacemaker (PM), exposure to electric or magnetic field of extremely low frequency creates inductions inside the human body that generate interference voltage which may cause the dysfunction of the implant. This thesis investigates the electromagnetic compatibility of cardiac implants subjected to an electric field low frequency (50/60 Hz). Computational simulations are effectuated in order to design an experimental bench for the exposure of a phantom including pacemakers or implantable defibrillators. A provocative study is established to define the electric field thresholds for preventing any malfunction of the implant. In numerical simulations; a virtual human model (digital phantom containing a cardiac implant) was placed in an upright position in a vertical exposure to an electric field. The finite element method was used to define the inductions in the cardiac implant level with a resolution of 2 mm (CST® software). In the experimental part, a test bench designed to allow generating an electric field up to 100 kV / m at frequencies 50-60 Hz was constructed, optimized and employed to investigate the behavior of cardiac implants.Several configurations were studied. 54 active cardiac implants (43 pacemakers and 11 defibrillators) are submitted to very high electric field of 50-60 Hz (up to 100 kV / m) inside the experimental bench. No failure was observed for public exposure levels for most configurations (+ 99%) except for six pacemakers in the case of a configuration clinically almost inexistent: unipolar mode with maximum sensitivity and atrial sensing.The implants configured with a nominal sensitivity in bipolar mode are resistant to electric fields exceeding the low action levels (ALs), even for the most high ALs, as defined by 2013 / 35 / EU
4
Zhou, Mengxi. "CEM des implants cardiaques aux basses fréquences 50 Hz dans un contexte normatif". Electronic Thesis or Diss., Université de Lorraine, 2023. http://www.theses.fr/2023LORR0110.
Abstract (sommario):
Les dispositifs médicaux implantables actifs (DMIA) ont été rapidement développés et largement appliqués pour le traitement des pathologies cardiaques avec des technologies constamment mises à jour au cours des dernières décennies. Le nombre croissant de porteurs de DMAI, y compris dans la population active, a entraîné un questionnement quant à leurs effets potentiels en présence d'un champ électromagnétique (CEM). Ces interrogations ont, dès les années 60, concerné les possibles interférences liées au réseau de transport de l'énergie. En effet, les fréquences allouées à l'énergie électrique (50 Hz et 60 Hz) sont dans la gamme que les signaux de l'activité cardiaque dont le spectre s'étend de quelques Hertz à 150 Hz environ. Les DMIA sont équipés de filtres sélectifs permettant de réduire considérablement ou d'éliminer les interférences. Toutefois, compte tenu de la nature des signaux cardiaques, il se peut que les fréquences de 50 Hz et 60 Hz ne soient pas filtrées afin de garantir une détection correcte et complète des ondes cardiaques. Sur les lieux de travail, certains travailleurs peuvent être soumis à des rayonnements électromagnétiques. La présence de travailleurs portant des DMIA est alors à considérer comme cas spécifiques. En d'autres termes, il convient d'accorder une attention particulière aux porteurs de DMIA qui sont exposés à des risques plus élevés et de mettre en place un processus d'évaluation des risques correspondant. La procédure d'évaluation des expositions aux CEM pour les travailleurs portant des DMIA a été régulée par la norme EN 50527 visant à déterminer le risque potentiel des expositions sur les lieux de travail. Le test d'immunité sur les DMIA est essentiel dans la procédure d'évaluation des risques et nécessite une méthode d'essai simple, reproductible et sans risque pour l'employé. Les expositions aux champs électriques à basse fréquence avaient reçu moins d'attention, bien qu'elles soient courantes sur les lieux de travail dans les industries électriques. Cette étude porte sur les expositions aux champs électriques de haute intensité de porteurs d'implants cardiaques. La bande de fréquence a été limitée à la fréquence du réseau européen, fréquence extrêmement basse de 50 Hz pour se concentrer sur les expositions professionnelles causées par les sources d'énergie. L'interférence peut être évaluée par l'estimation de la tension induite à l'entrée au niveau de la sonde de l'implant cardiaque. Des systèmes équivalents peuvent être élaborés pour reproduire les expositions et les conditions d'implantation afin de générer les mêmes effets à l'entrée de l'implant cardiaque. Dans ce travail, une étude théorique et expérimentale a été réalisée sur un fantôme in vitro. Cette étude a permis de déterminer la tension induite aux bornes de la sonde d'un implant cardiaque soumis à un champ électrique important à 50 Hz. Le fantôme se compose de deux zones de caractéristiques électriques similaires à celles du cœur humain et de la cage thoracique, lieux où la sonde cardiaque et le boîtier sont implantés. Les mesures expérimentales et la simulation numérique concordent ce qui valide les facteurs d'équivalence que nous avons trouvés pour notre système. Ainsi le fantôme in vitro peut être appliqué comme système équivalent dans les travaux sur la CEM des implants cardiaques. Un autre résultat que nous avons établi dans cette étude est l'équivalence entre un système d'exposition au champ électrique et un système par injection. Cette relation d'équivalence nous permet de ramener une étude sous champ électrique, dont la mise en œuvre est complexe, à une étude en perturbations conduites, beaucoup plus simple à réaliserTargeting cardiology diagnosis and treatment, active implantable medical devices (AIMDs) have been rapidly developed and widely applied with constantly updated technologies in recent decades. It is vital for scientific research to catch up with the speed of the information era in terms of the side effects on human beings and the environment. Pacemakers (PMs), used for the treatment of arrhythmias (bradycardias and tachycardias), and implantable cardioverter defibrillators (ICDs), for palliating serious ventricular arrhythmias by electric shocks to the myocardial tissue are important AIMDs normally implanted in the human chest. Electromagnetic radiation is inevitable present in our surroundings and raised many questions concerning the potential effects on the AIMD-wearers. The increasing number of medical implant wearers, including those in active professional activities, has led to questions regarding their performance in the presence of an occupational electromagnetic field (EMF) exposure. Since the 1960s, these questions have concerned possible interference linked to the energy transport network. The frequencies allocated to electrical energy (50 Hz and 60 Hz) are in the analysis bandwidth of the cardiac signals, of which spectrum extends from a few Hertz to approximately 150 Hz. The AIMDs are usually equipped with selective filters enabling to significantly reduce or eliminate the interference. However, considering the nature formation of the heart signals, 50 Hz and 60 Hz may not be filtered in order to ensure the cardiac signal waves are correctly and completely sensed.In the workplaces, it is inevitable to have the existence of workers who are susceptible to the electromagnetic field (EMF)-related impact. The presence of workers wearing AIMDs is then to be considered as specific cases. In other words, particular attention should be given to AIMD carriers who are subject to higher risks and corresponding risk evaluation process should be established. The procedure for assessing the EMF exposures for workers bearing AIMDs was proposed in EN 50527 to determine the risk arising from the exposures in the workplaces. Immunity test on AIMDs is critical in the risk assessment procedure and requires a simple, feasible, and risk-free test method. To date, the electric field exposures at low frequencies has received little attention yet they commonly exist in the workplaces in electrical industries, for example, area near power lines and substations. In this study, high-intensity electric field exposures are mainly concerned. The frequency band was limited to extremely low frequency at 50 Hz to focus on the occupational exposures caused by power sources.The interference can be evaluated by the estimation of the induced voltage at its input. Equivalent systems can be built up by adopting this conception to reproduce the exposures and the implantation conditions in order to generate same effects at the input of cardiac implant (same induced voltage). In this work, a theoretical and experimental study was performed on an in vitro phantom that allowed to determine the voltage induced at the input of a cardiac implant subjected to a high-intensity electric field at 50 Hz. The phantom is composed of two parts with electrical characteristics similar to those of the human heart and the chest, where the cardiac lead and the housing are implanted. Experimental measurements and numerical simulation are coherent which validates the equivalence factors we found for our systems. Thus, the in vitro phantom can be applied as an equivalent system in the workplace for the immunity test on cardiac implants. Another result we established in this study is the equivalence between an electric field exposure system and an injection system which allows us to reduce the complexity of the study, and conduct simpler tests with reproduced perturbations
5
Siegel, Alice. "Etude de l’interaction mécanique entre un dispositif médical implantable actif crânien et le crâne face à des sollicitations dynamiques". Thesis, Paris, ENSAM, 2019. http://www.theses.fr/2019ENAM0012.
Abstract (sommario):
Dans le cadre du développement accru d’implants crâniens actifs, l’étude de la résistance du complexe crâne-implant face à des chocs modérés est nécessaire afin d’assurer la sécurité du patient. Le but de cette thèse est de quantifier l’interaction mécanique entre le crâne et l’implant afin de développer un modèle éléments finis prédictif utilisable pour la conception des futurs dispositifs. Dans un premier temps, des essais matériaux sur titane et silicone ont permis d’extraire les paramètres élastiques, plastiques et de viscosité de leurs lois de comportement. Ces paramètres ont ensuite été implémentés dans un modèle éléments finis de l’implant sous sollicitations dynamiques, validé par des essais de choc de 2,5 J. L’implant dissipe une partie de l’énergie du choc et le modèle obtenu permet d’optimiser la conception de l’implant afin qu’il reste fonctionnel et étanche après l’impact. La troisième partie porte sur l’élaboration d’un modèle éléments finis du complexe crâne-implant sous sollicitations dynamiques. Des essais sur têtes cadavériques ovines ont permis d’optimiser les paramètres d’endommagement du crâne. Le modèle complet du complexe crâne-implant, corrélé à des essais de choc, apporte des éléments de réponses sur le comportement du crâne implanté face un choc mécanique, permettant ainsi d’optimiser la conception de l’implant afin de garantir l’intégrité du crâne.Ce modèle représente un premier outil pour l’analyse de l’interaction mécanique entre crâne et implant actif, et permet de dimensionner ce dernier de sorte à garantir son fonctionnement et son étanchéité, tout en assurant l’intégrité du crâneActive cranial implants are more and more developed to cure neurological diseases. In this context it is necessary to evaluate the mechanical resistance of the skull-implant complex under impact conditions as to ensure the patient’s security. The aim of this study is to quantify the mechanical interactions between the skull and the implant as to develop a finite element model for predictive purpose and for use in cranial implant design methodologies for future implants. First, material tests were necessary to identify the material law parameters of titanium and silicone. They were then used in a finite element model of the implant under dynamic loading, validated against 2.5 J-impact tests. The implant dissipates part of the impact energy and the model enables to optimize the design of implants for it to keep functional and hermetic after the impact. In the third part, a finite element model of the skull-implant complex is developed under dynamic loading. Impact tests on ovine cadaver heads are performed for model validation by enhancing the damage parameters of the three-layered skull and give insight into the behavior of the implanted skull under impact.This model is a primary tool for analyzing the mechanical interaction between the skull and an active implant and enables for an optimized design for functional and hermetic implants, while keeping the skull safe
Libri sul tema "Active medical implants":
1
ANSI/AAMI/ISO 14708-3:2017; Implants for surgery — Active implantable medical devices — Part 3: Implantable neurostimulators. AAMI, 2017. http://dx.doi.org/10.2345/9781570206580.
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ANSI/AAMI/ISO 14708-4:2008/(R)2011; Implants for surgery—Active implantable medical devices—Part 4: Implantable infusion pumps. AAMI, 2009. http://dx.doi.org/10.2345/9781570203596.
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Dössel, Olaf, e Wolfgang C. Schlegel. World Congress on Medical Physics and Biomedical Engineering September 7 - 12, 2009 Munich, Germany: Vol. 25/VIII Micro- and Nanosystems in Medicine, Active Implants, Biosensors. Springer, 2010.
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ANSI/AAMI/ISO 14708-1:2014; Implants for surgery — Active implantable medical devices — Part 1: General requirements for safety, marking and for information to be provided by the manufacturer. AAMI, 2014. http://dx.doi.org/10.2345/9781570205651.
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Handbook of Biodegradable Polymers (Medical Reference and Soci and Delivery). CRC, 1998.
Capitoli di libri sul tema "Active medical implants":
1
Koch, Klaus P., e Oliver Scholz. "Telemedicine Using Active Implants". In Springer Handbook of Medical Technology, 1129–37. Berlin, Heidelberg: Springer Berlin Heidelberg, 2011. http://dx.doi.org/10.1007/978-3-540-74658-4_61.
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Sampath, Thamizharasan, Sandhiya Thamizharasan e Prakash Srinivasan Timiri Shanmugam. "ISO 21534: Non-active Surgical Implants – Joint Replacement Implants". In Medical Device Guidelines and Regulations Handbook, 75–82. Cham: Springer International Publishing, 2022. http://dx.doi.org/10.1007/978-3-030-91855-2_5.
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Singh, Karnika. "ISO 16061: Instrumentation for Use in Association with Non-active Surgical Implants—General Requirements". In Medical Device Guidelines and Regulations Handbook, 83–90. Cham: Springer International Publishing, 2022. http://dx.doi.org/10.1007/978-3-030-91855-2_6.
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Bratu, Erin, Robert Dwyer e Jack Noble. "A Graph-Based Method for Optimal Active Electrode Selection in Cochlear Implants". In Medical Image Computing and Computer Assisted Intervention – MICCAI 2020, 34–43. Cham: Springer International Publishing, 2020. http://dx.doi.org/10.1007/978-3-030-59716-0_4.
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Filipović, Nenad, Nina Tomić, Maja Kuzmanović e Magdalena M. Stevanović. "Nanoparticles. Potential for Use to Prevent Infections". In Urinary Stents, 325–39. Cham: Springer International Publishing, 2022. http://dx.doi.org/10.1007/978-3-031-04484-7_26.
Abstract (sommario):
AbstractOne of the major issues related to medical devices and especially urinary stents are infections caused by different strains of bacteria and fungi, mainly in light of the recent rise in microbial resistance to existing antibiotics. Lately, it has been shown that nanomaterials could be superior alternatives to conventional antibiotics. Generally, nanoparticles are used for many applications in the biomedical field primarily due to the ability to adjust and control their physicochemical properties as well as their great reactivity due to the large surface-to-volume ratio. This has led to the formation of a new research field called nanomedicine which can be defined as the use of nanotechnology and nanomaterials in diagnostics, imaging, observing, prevention, control, and treatment of diseases. For example, coverings or coatings based on nanomaterials are now seen as a promising strategy for preventing or treating biofilms formation on healthcare kits, implants, and medical devices. Toxicity, inappropriate delivery, or degradation of conventionally used drugs for the treatment of infections may be avoided by using nanoparticles without or with encapsulated/immobilized active substances. Most of the materials which are used and examined for the preparation of the nanoparticles with encapsulated/immobilized active substances or smart reactive nanomaterials with antimicrobial effects are polymers, naturally derived antimicrobials, metal-based and non-metallic materials. This chapter provides an overview of the current state and future perspectives of the nanoparticle-based systems based on these materials for prevention, control, or elimination of biofilm-related infections on urinary stents. It also addresses manufacturing conditions indicating the huge potential for the improvement of existing and development of new promising stent solutions.
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Rahmat-Samii, Yahya, e Jaehoon Kim. "Planar Antennas for Active Implantable Medical Devices". In Implanted Antennas in Medical Wireless Communications, 57–69. Cham: Springer International Publishing, 2006. http://dx.doi.org/10.1007/978-3-031-01531-1_6.
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Brown, James E., Paul J. Stadnik, Jeffrey A. Von Arx e Dirk Muessig. "RF-induced Heating Near Active Implanted Medical Devices in MRI: Impact of Tissue Simulating Medium". In Brain and Human Body Modelling 2021, 125–32. Cham: Springer International Publishing, 2022. http://dx.doi.org/10.1007/978-3-031-15451-5_8.
Abstract (sommario):
AbstractRecent advances in the MR conditional safety assessment of active implantable medical devices (AIMDs) have begun providing guidelines in the development of transfer functions for evaluating risk to the patient due to RF-induced heating. This work introduces the complexity of the analysis of RF-induced heating and explores the impact of the computational human model (CHM) on the resulting analysis. Through historical analysis techniques, simplified structures, and real medical device geometries, the interaction of the AIMD lead with the tissue simulating medium (TSM) can be better understood. Finally, a general guiding principle for MR manufacturers is identified, whereby the thickness of the lead insulation can be used to determine the appropriate TSM for the most accurate in vivo predictions of RF-induced heating.
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Cohen, DDS, Nicolas. "Periodontal and Implant Treatment With Computerized Occlusal Analysis". In Advances in Medical Technologies and Clinical Practice, 1125–74. IGI Global, 2020. http://dx.doi.org/10.4018/978-1-5225-9254-9.ch016.
Abstract (sommario):
The role of occlusion in the progression of periodontal disease remains a controversial subject. Occlusal force, which is a mechanical stress applied to tissues, has always been considered to not initiate, nor accelerate, periodontal attachment loss resultant from inflammatory periodontal disease. This chapter outlines this controversy in great detail, from the perspective that the absence of a validated occlusal force and timing measuring device that can quantify the occlusion, has contributed to the confusion and questions that exist in the scientific community about the relationship between both periodontal disease and peri-implantitis, and the occlusion. The development of a new occlusal measurement technology that records and analyzes precise and reproducible relative occlusal contact force levels in real-time, independent of a clinician's subjectivity, is helping to change the scientific opinion regarding occlusion's role in periodontal and peri-implant supporting tissue loss. The T-Scan 10 system is particularly adapted for treating patients who demonstrate tissue loss combined with occlusal issues. Indeed, after having controlled the major etiologic and risk factors of periodontal disease and peri-implantitis, adjusting the occlusion after active tissue and implant therapy favors healing. The outcome of periodontal treatment aimed at compromised teeth and dental implants, combined with occlusal force excess control from computer-guided targeted occlusal adjustments, is highly predictable, and is characterized by less inflammation, a decrease of probing depths, and the stabilization of bone levels around teeth and dental implants.
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"Implants for surgery — Active implantable medical devices — Part 3: Implantable neurostimulators". In ANSI/AAMI/ISO 14708-3:2017; Implants for surgery — Active implantable medical devices — Part 3: Implantable neurostimulators. AAMI, 2017. http://dx.doi.org/10.2345/9781570206580.ch1.
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Censi, Federica, Eugenio Mattei e Giovanni Calcagnini. "MRI interactions with medical devices". In The EACVI Textbook of Cardiovascular Magnetic Resonance, a cura di Massimo Lombardi, Sven Plein, Steffen Petersen, Chiara Bucciarelli-Ducci, Emanuela R. Valsangiacomo Buechel, Cristina Basso e Victor Ferrari, 70–76. Oxford University Press, 2018. http://dx.doi.org/10.1093/med/9780198779735.003.0012.
Abstract (sommario):
Given the particular environment created by a magnetic resonance imaging (MRI) scanner, various kinds of interaction can occur with other medical devices, depending on the nature of the device, active or passive, on the materials. Generally speaking, manufacturers of medical devices must analyse and indicate any potential risk related to reasonably foreseeable environmental conditions such as magnetic fields and to other medical treatments such as MRI. Thus, information about the compatibility of a medical device with MRI should be available on the device user manual. According to the latest international standard (ASTM 2503), a medical device can be magnetic resonance (MR) Safe, MR Conditional, and MR Unsafe. MR Safe poses no known hazards in all MRI environments; MR Conditional has been demonstrated to pose no known hazards in a specified MRI environment with specified conditions of use; MR Unsafe is known to pose hazards in all MRI environments. Implanted medical devices are those raising major concerns in MR environments. Each implanted device must be clearly identified, and it is important to screen each patient before MRI examination. The prevalence of patients with various kinds of implants is increasing. For these devices, it could be important to refer not only to the user manual, but also to the scientific literature. Indeed, it could happen that it is necessary to perform an MRI examination which does not completely respect the MRI conditions indicated by the device manufacturer. In these cases, the clinical or in vitro experiences reported in the scientific literature could help in yielding elements to support the medical decision.
Atti di convegni sul tema "Active medical implants":
1
Gallichan, Robert, David M. Budgett e Daniel McCormick. "600mW Active Rectifier with Shorting-Control for Wirelessly Powered Medical Implants". In 2018 IEEE Biomedical Circuits and Systems Conference (BioCAS). IEEE, 2018. http://dx.doi.org/10.1109/biocas.2018.8584813.
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Hoffmann, Klaus-Peter, Roman Ruff, Wiebke Droste, Rudiger Rupp, Heidi Olze, Werner Kneist, Jonas Friedrich Schiemer et al. "Technical, Medical and Ethical Challenges in Networks of Smart Active Implants*". In 2019 41st Annual International Conference of the IEEE Engineering in Medicine & Biology Society (EMBC). IEEE, 2019. http://dx.doi.org/10.1109/embc.2019.8856977.
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Li, Tianhui, Hailing Fu, Stephanos Theodossiades e Sotiris Korossis. "Simultaneous Ultrasonic Power Transfer and Depth Feedback for Active Medical Implants". In 2023 IEEE International Conference on Mechatronics (ICM). IEEE, 2023. http://dx.doi.org/10.1109/icm54990.2023.10101914.
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Drexler, Elizabeth S., Andrew J. Slifka, Nicholas Barbosa e John W. Drexler. "Interaction of Environmental Conditions: Role in the Reliability of Active Implantable Devices". In ASME 2007 2nd Frontiers in Biomedical Devices Conference. ASMEDC, 2007. http://dx.doi.org/10.1115/biomed2007-38072.
Abstract (sommario):
Environmental conditions can have major influence on the lifetimes and reliability of active implantable medical devices (e.g., neurostimulators, cochlear implants, internal cardioverter defibrillators). These environmental conditions can range from those encountered by the device in processing and production to transportation and storage to actual operation. Although one might argue that the environmental conditions found in the first two situations are harsher than those of the third, failures that result from those situations are screened before implantation. If we assume that the active medical device is in perfect operational form at the time it is implanted, it will still experience a host of environmental conditions that can affect reliability. In fact, the ultimate goal of these medical devices is to restore the patient, wherever they may reside, to normal activities. A list of some environmental conditions that may be experienced by a device implanted in a representative patient is found in Table 1.
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Nerem, Robert M. "Tissue Engineering: The Next Generation of Medical Implants". In ASME 1996 International Mechanical Engineering Congress and Exposition. American Society of Mechanical Engineers, 1996. http://dx.doi.org/10.1115/imece1996-1161.
Abstract (sommario):
Abstract The engineering of living tissue, i.e. tissue engineering, involves the use of living cells, manipulated through their extracellular environment or even genetically, to develop biological substitutes for implantation into the body and/or to foster the remodeling of tissue in some other active manner (1). The purpose is to either repair, replace, maintain, or enhance the function of a particular tissue or organ. For some organs, the first step will be extracorporeal devices; however, the long term goal of tissue engineering should be either implantable systems or the in vivo remodeling of tissue. Because there are not enough organs available for transplantation to meet the needs of the individuals on waiting lists, there is a real need for tissue-engineered biological substitutes.
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Ramos-Homs, Amy. "Synthesis of Bone Scaffold for Pediatric Bone Defects Using 3D Printing". In MME Undergraduate Research Symposium. Florida International University, 2022. http://dx.doi.org/10.25148/mmeurs.010560.
Abstract (sommario):
Pediatric bone defects, requiring surgical interventions and implants, include malignant and nonmalignant bone tumors and trauma fractures. Malignant bone tumors (MBT), such as Osteosarcoma and Ewing sarcoma, are aggressive primary cancers that affect growing adolescent bones (10- to 19-year-olds) and require complex reconstruction due to large bone excision during surgical interventions. Pediatric bone fractures requiring surgical interventions peak in 10- to 14-year-olds and are a major public health concern in the US with an impact on patients, parents, and healthcare costs of approx. 350 billion. These diseases require bone tissue replacement in changing bones. Bone reconstruction and medical implant design for growing pediatric bones have unique challenges due to active growth and there is a greater need for active, resorbable, and patient-specific implants to prevent growth impediments. The current available pediatric implant is limited in addressing these needs and is primarily addressed by static metallic implants designed for adults. We plan to work towards the design and synthesis of a bone scaffold by modifying a CAD model considering the size of the porosity in the structure of the pediatric bone. This modified model will be 3D printed and subjected to tests to evaluate the strength and composition of the scaffold. Afterwards, the scaffold is used for cell culture in hopes of eliciting cellular response for bone formation and cell regeneration, since a key factor to assess is whether the scaffold will grow with the bone, or the bone will grow with the scaffold. This is done to support the attachment of cells on the surface of the bone to actively support bone modeling processes under structural changes of growing bones.
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Zimmer, Lukas, Rouven Britz, Yannik Goergen, Gianluca Rizzello, Tim Pohlemann, Marcel Orth, Bergita Ganse, Stefan Seelecke e Paul Motzki. "An SMA-Based Multifunctional Implant for Improved Bone Fracture Healing". In ASME 2021 Conference on Smart Materials, Adaptive Structures and Intelligent Systems. American Society of Mechanical Engineers, 2021. http://dx.doi.org/10.1115/smasis2021-67261.
Abstract (sommario):
Abstract In this paper, a shape memory alloy (SMA) based, multifunctional smart implant for improved bone fracture healing is presented. In contrast to conventionally used medical implants such as intramedullary nails or bone plates supporting a fractured bone in a passive way, the developed smart implant has on the one hand the ability to work as a common stabilizing implant. On the other hand, the smart implant has the property to stimulate the fracture to improve the bone healing process by controlled contracting micro movements. The smart implant consists of one mechanism to change the stiffness of the implant and one mechanism for the active stimulation purpose. Both actuator mechanisms are realized with the help of Nitinol SMA actuator wires, that are suitable for medical applications because of their biocompatibility. In addition to their actuator property the smart “self-sensing” ability of the SMA wires is used to control the actuator movements. This work focuses mainly on the development and the design of the smart implant prototype and the parts are produced via 3D rapid prototyping.
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Zhao, Jianming, e Yuan Gao. "A 13.56 MHz Active Rectifier with PMOS AC-DC Interface for Wireless Powered Medical Implants". In 2021 IFIP/IEEE 29th International Conference on Very Large Scale Integration (VLSI-SoC). IEEE, 2021. http://dx.doi.org/10.1109/vlsi-soc53125.2021.9606992.
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Nanbakhsh, Kambiz, Marta Kluba, Barbara Pahl, Florian Bourgeois, Ronald Dekker, Wouter Serdijn e Vasiliki Giagka. "Effect of Signals on the Encapsulation Performance of Parylene Coated Platinum Tracks for Active Medical Implants". In 2019 41st Annual International Conference of the IEEE Engineering in Medicine & Biology Society (EMBC). IEEE, 2019. http://dx.doi.org/10.1109/embc.2019.8857702.
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Yang, Lijian, Mir Khadiza Akter, Ran Guo, Jianfeng Zheng e Ji Chen. "Evaluation of MRI RF-induced for Active Implantable Medical Implants in the vicinity of other implantable devices". In 2023 IEEE/MTT-S International Microwave Symposium - IMS 2023. IEEE, 2023. http://dx.doi.org/10.1109/ims37964.2023.10188203.