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Sansur, Charles A., Nicholas M. Caffes, David M. Ibrahimi, Nathan L. Pratt, Evan M. Lewis, Ashley A. Murgatroyd e Bryan W. Cunningham. "Biomechanical fixation properties of cortical versus transpedicular screws in the osteoporotic lumbar spine: an in vitro human cadaveric model". Journal of Neurosurgery: Spine 25, n. 4 (ottobre 2016): 467–76. http://dx.doi.org/10.3171/2016.2.spine151046.
Testo completoAbstract (sommario):
OBJECTIVE Optimal strategies for fixation in the osteoporotic lumbar spine remain a clinical issue. Classic transpedicular fixation in the osteoporotic spine is frequently plagued with construct instability, often due to inadequate cortical screw–bone purchase. A cortical bone trajectory maximizes bony purchase and has been reported to provide increased screw pullout strength. The aim of the current investigation was to evaluate the biomechanical efficacy of cortical spinal fixation as a surgical alternative to transpedicular fixation in the osteoporotic lumbar spine under physiological loading. METHODS Eight fresh-frozen human spinopelvic specimens with low mean bone mineral densities (T score less than or equal to –2.5) underwent initial destabilization, consisting of laminectomy and bilateral facetectomies (L2–3 and L4–5), followed by pedicle or cortical reconstructions randomized between levels. The surgical constructs then underwent fatigue testing followed by tensile load to failure pullout testing to quantify screw pullout force. RESULTS When stratifying the pullout data with fixation technique and operative vertebral level, cortical screw fixation exhibited a marked increase in mean load at failure in the lower vertebral segments (p = 0.188, 625.6 ± 233.4 N vs 450.7 ± 204.3 N at L-4 and p = 0.219, 640.9 ± 207.4 N vs 519.3 ± 132.1 N at L-5) while transpedicular screw fixation demonstrated higher failure loads in the superior vertebral elements (p = 0.024, 783.0 ± 516.1 N vs 338.4 ± 168.2 N at L-2 and p = 0.220, 723.0 ± 492.9 N vs 469.8 ± 252.0 N at L-3). Although smaller in diameter and length, cortical fixation resulted in failures that were not significantly different from larger pedicle screws (p > 0.05, 449.4 ± 265.3 N and 541.2 ± 135.1 N vs 616.0 ± 384.5 N and 484.0 ± 137.1 N, respectively). CONCLUSIONS Cortical screw fixation exhibits a marked increase in mean load at failure in the lower vertebral segments and may offer a viable alternative to traditional pedicle screw fixation, particularly for stabilization of lower lumbar vertebral elements with definitive osteoporosis.
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Yan, Wei-Hong, e Wan-Yao Chen. "Crystal structure of 1,1′-(1,2-ethanediyl)bis(pyridin-1-ium) bis(1,2-dicyanoethene-1,2-dithiolato-κ2 S:S)nickel(II), C20H14N6NiS4". Zeitschrift für Kristallographie - New Crystal Structures 237, n. 2 (31 gennaio 2022): 235–36. http://dx.doi.org/10.1515/ncrs-2021-0433.
Testo completoAbstract (sommario):
Abstract C20H14N6NiS4, triclinic, P 1 ‾ $P\overline{1}$ (no. 2), a = 8.519(3) Å, b = 8.5956(16) Å, c = 8.6531(17) Å, α = 116.404(3)°, β = 94.574(4)°, γ = 103.031(4)°, V = 541.0(2) Å3, Z = 1, R gt (F) = 0.0445, wR ref(F 2) = 0.1147, T = 296.15 K.
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Silva, Evandro Manoel da, Reginaldo Gomes Nobre, Leandro De Pádua Souza, Francisco Wesley Alves Pinheiro, Geovani Soares de Lima, Hans Raj Gheyi e Luana Lucas de Sá Almeida. "Physiology of ‘Paluma’ guava under irrigation with saline water and nitrogen fertilization". Semina: Ciências Agrárias 38, n. 2 (2 maggio 2017): 623. http://dx.doi.org/10.5433/1679-0359.2017v38n2p623.
Testo completoAbstract (sommario):
The use of saline water in irrigation causes osmotic and toxic effects and nutritional imbalance in plants, leading to morphophysiological modifications in the leaves and compromising the production of photosynthetic pigments, which negatively reflects in the growth and development of the crops. Hence, this study aimed to evaluate the effect of irrigation water salinity on the content of photosynthetic pigments and leaf morphophysiology of guava seedlings cv. ‘Paluma’ under nitrogen (N) fertilization. A randomized block design was used, testing five levels of irrigation water electrical conductivity - ECw (0.3, 1.1, 1.9, 2.7, and 3.5 dS m-1) and four N doses (541.1, 773.0, 1,004.9, and 1,236.8 mg of N dm-3 of soil) in a 5 x 4 factorial scheme with three replicates and five plants per plot. The contents of photosynthetic pigments in the leaves of the guava seedlings cv. ‘Paluma’ were inhibited by the increase in irrigation water salinity at 190 days after emergence, and the salt stress was lessened with the N dose of 1,004.9 mg dm-3 up to an ECw level of 1.2 dS m-1. Leaf morphophysiology of guava seedlings was not compromised by irrigation water salinity up to 1.5 dS m-1, and the highest values were obtained in plants fertilized with 541.1 mg of N dm-3.
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Lu, Liping, e Xiyan Zhang. "Optimization of the low temperature combustion synthesis of Er3+ doped lead–natrium–yttrium–fluoride phosphor". Functional Materials Letters 07, n. 01 (febbraio 2014): 1450004. http://dx.doi.org/10.1142/s1793604714500040.
Testo completoAbstract (sommario):
The low-temperature combustion synthesis (LCS) method is the most popular method for the synthesis of ultrafine oxides and compound oxides. A kind of Er - Y - Pb - Na quaternary fluoride sensitive to 1.55 μm was synthesized by the LCS method and the synthesis conditions were optimized with orthogonal experiments. Intense upconversion emissions at 522 nm, 541.4 nm and 654.7 nm corresponding to the 2 H 11/2, 4 S 3/2 and 4 F 9/2 transitions to the 4 I 15/2 ground state were observed when excited by CW laser radiation at 1.55 μm. The effect of the carbamide amount on the phase formation and the luminescence intensity was analyzed. The product is of uniform particle size of ca. 40 nm, which is very outstanding for its reutilization in the infrared detection field.
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Fan, Xiao-Man, Jia-Ying Huang, Xiao-Min Ling, Wei Wei, Wen-Bin Su e Ye-Wang Zhang. "A Highly Active Chondroitin Sulfate Lyase ABC for Enzymatic Depolymerization of Chondroitin Sulfate". Polymers 14, n. 9 (27 aprile 2022): 1770. http://dx.doi.org/10.3390/polym14091770.
Testo completoAbstract (sommario):
Enzymatic preparation of low-molecular-weight chondroitin sulfate (LMWCS) has received increasing attention. In this work, a chondroitin sulfate lyase ABC (Chon-ABC) was successfully cloned, expressed, and characterized. The Km and Vmax of the Chon-ABC were 0.54 mM and 541.3 U mg−1, respectively. The maximal activity was assayed as 500.4 U mg−1 at 37 °C in pH 8.0 phosphate buffer saline. The half-lives of the Chon-ABC were 133 d and 127 min at 4 °C and 37 °C, respectively. Enzymatic preparation of LMWCS was performed at room temperature for 30 min. The changes between the substrate and product were analyzed with mass spectrometry (MS), high-performance liquid chromatography (HPLC), gel permeation chromatography (GPC), and nuclear magnetic resonance (NMR). Overall, the Chon-ABC from Bacteroides thetaiotaomicron is competitive in large-scale enzymatic preparation of LMWCS for its high activity, stability, and substrate specificity.
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Emmerling, Franziska, e Caroline Röhr. "Die neuen Oxoarsenate(III) AAsO2 (A = Na, K, Rb) und Cs3As5O9. Darstellung, Kristallstrukturen und Raman-Spektren / The New Oxoarsenates(III) AAsO2 (A = Na, K, Rb) and Cs3As5O9. Synthesis, Crystal Structures and Raman Spectra". Zeitschrift für Naturforschung B 58, n. 7 (1 luglio 2003): 620–26. http://dx.doi.org/10.1515/znb-2003-0704.
Testo completoAbstract (sommario):
The new alkaline metal arsenates(III) were synthesized at a temperature of 500 °C via reaction of stoichiometric mixtures of the elemental alkali metals A and As2O3. In the crystal structures of the four title compounds, which have been determined by single crystal x-ray diffraction, the As(III) atoms are in ψ-tetrahedral coordination by oxygen exclusively. In NaAsO2 (orthorhombic, space group Pbcm, a = 1429.6(9), b = 677.3(3), c = 509.1(2) pm, Z = 8) and the compounds AAsO2 (A = K/Rb, orthorhombic, space group Pbcm, a = 715.1(2)/729.7(5), b =748.0(1)/775.2(5), c = 539.20(17)/541.1(3) pm, Z = 4) the AsO3 ψ-tetrahedra are condensed to form zig-zag chains [AsOO2/2]−. In the Cs phase Cs3As5O9 with a lower alkaline metal content (trigonal, space group P31m, a = 845.5(3), c = 602.6(2) pm, Z = 1) the two crystallographically independent ψ-tetrahedra AsO3/2 and AsOO2/2 are connected in a 2:3 ratio to give polar sheets [As5O9]3−.
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Boalch, Gerald T. "MARY PARKE (1908–1989)". Phycologia 29, n. 4 (dicembre 1990): 541–42. http://dx.doi.org/10.2216/i0031-8884-29-4-541.1.
Testo completo
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Martinez, Maria, Monica Ausejo, J. Luis Miguel, M. Luisa Gonzalez, Gloria Balaguer, Pilar Catalan e Rafael Selgas. "Comparative Study between Intact PTH and Fragments of PTH in Patients on Hemodialysis and CAPD". Peritoneal Dialysis International: Journal of the International Society for Peritoneal Dialysis 11, n. 2 (aprile 1991): 137–40. http://dx.doi.org/10.1177/089686089101100207.
Testo completoAbstract (sommario):
Twenty-nine patients on hemodialysis (HO) and 29 patients on continuous ambulatory peritoneal dialysis (CAPO) were studied. Serum calcium and phosphorous levels were similar in the 2 groups. Serum parathyroid hormone (PTH) levels were determined by 4 different methods. Mid-molecule PTH levels were higher in HO (1099.5±876.8 pmol/L) than in CAPO patients (541.0±138.8 pmol/L), p<0.001, while intact PTH levels were similar. The ratio MM-PTHllntact PTH was higher in HO (55.2±29.0) than in CAPO patients (39.0±20.0), where p<0.01. In patients with similar C-PTH, those on CAPO had higher levels of intact PTH (46.0±27.0 pmollL) than those in HO (29.3±29.0 pmoIIL), p<0.01. The ratio C-PTHlintact PTH was higher in HO (104.9±39.6) than in CAPO patients (59.3±32.3), p<0.001. The Peritoneal Saturation Index (PSI) of MMPTH was 23.4±12%, and it showed a hyperbolic correlation in respect to MM-PTH serum levels. We concluded that CAPO can modify the plasma C-PTH and MM-PTH serum levels by peritoneallosses of these fragments.
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Zheng, Hao. "Analysis of Aroma Components of Enzymatic Hydrolysis Products of Oak Lignin from Different Producing Areas". International Journal of Natural Resources and Environmental Studies 2, n. 2 (25 aprile 2024): 12–23. http://dx.doi.org/10.62051/ijnres.v2n2.02.
Testo completoAbstract (sommario):
The morphology and structure of lignin in French oak, American oak and Chinese Mongolian oak were observed and compared by scanning electron microscopy (SEM). The results showed that the surface of lignin after enzymatic hydrolysis was more irregular and the contact area was obviously increased. GC-MS detected 3 kinds of lignin, 4 kinds of components and 30 kinds of volatile substances. The lignin content of French oak was the highest (8911.5 ± 512.2 μg/L, 29 kinds), followed by that of American oak (8071.7 ±541.9 μg/L, 26 kinds), and that of Mongolian oak was the least (7903.3 ± 492.5 μg/L, 26 kinds). The results of aroma characteristics analysis, principal component analysis and heat map analysis showed that the aroma components of the three kinds of oak lignin were significantly different. French oak lignin could provide more volatile phenols, with obvious smoky, woody and sweet flavor. Mongolian oak lignin carries more phenolic and ester compounds, providing a relatively soft floral, fruity flavor. American oak lignin has a relatively average aroma substance content, which can bring strong and complex complex aroma characteristics.
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Souza, Leandro de P., Reginaldo G. Nobre, Evandro M. da Silva, Geovani S. de Lima, Francisco W. A. Pinheiro e Luana L. de S. Almeida. "Formation of ‘Crioula’ guava rootstock under saline water irrigation and nitrogen doses". Revista Brasileira de Engenharia Agrícola e Ambiental 20, n. 8 (agosto 2016): 739–45. http://dx.doi.org/10.1590/1807-1929/agriambi.v20n8p739-745.
Testo completoAbstract (sommario):
ABSTRACT The objective of this research was to evaluate the growth and formation of fresh and dry weight of ‘Crioula’ guava rootstock irrigated with waters of different saline levels and nitrogen (N) doses, in an experiment conducted in plastic tubes under greenhouse conditions. The experimental design was randomized blocks, in a 5 x 4 factorial scheme with four replicates, and the treatments consisted of five levels of water electrical conductivity - ECw (0.3, 1.1, 1.9, 2.7 and 3.5 dS m-1) and four N doses (70, 100, 130 and 160% of the N dose recommended for the cultivation of guava seedlings, cv. ‘Paluma’). The dose referring to 100% corresponds to 773 mg of N dm-3. The highest growth of ‘Crioula’ guava rootstock was obtained with ECw of 0.3 dS m-1 and fertilization of 541.1 mg N dm-3 of soil; increasing N doses did not reduce the deleterious effect of the salt stress on the growth and phytomass formation of ‘Crioula’ guava rootstock; irrigation with water of up to 1.75 dS m-1, in the production of guava rootstocks, promotes acceptable reduction of 10% in growth and quality of the seedlings.
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Singh, Raj Gaurav, Kai Chun Li, Karl Michael Lyons e John Neil Waddell. "Effect of Two Brands of Glaze Material on the Flexural Strength and Probability of Failure of High Translucent Monolithic Zirconia". Materials 14, n. 22 (19 novembre 2021): 7022. http://dx.doi.org/10.3390/ma14227022.
Testo completoAbstract (sommario):
(1) Background: The effect of glazing on the mechanical properties of monolithic high translucent zirconia is not well reported. Therefore, the purpose of this study was to evaluate the effect of glazing on the flexural strength of high translucent zirconia; (2) Methods: Ninety specimens were prepared from second-generation 3Y-TZP high translucent blocks and divided into three groups. Glaze materials were applied on one surface of the specimen and subjected to a four-point bending test and flexural stress and flexural displacement values were derived. Descriptive fractographic analysis of surfaces was conducted to observe the point of failure and fracture pattern.; (3) Results: Control-nonglazed (647.17, 1σ = 74.71 MPa) presented higher flexural strength values compared to glaze I (541.20, 1σ = 82.91 MPa) and glaze II (581.10, 1σ = 59.41 MPa). Characteristic strength (σƟ) from Weibull analysis also observed higher (660.67 MPa) values for the control specimens. Confocal microscopy revealed that glazed surfaces were much rougher than control surfaces. Descriptive fractographic analysis revealed that there was no correlation between the point of failure initiation and flexural strength; (4) Conclusions: The test results demonstrated that glazing significantly decreased the flexural strength and flexural displacement of the zirconia specimens.
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Bezerra, Idelfonso L., Reginaldo G. Nobre, Hans R. Gheyi, Leandro de P. Souza, Francisco W. A. Pinheiro e Geovani S. de Lima. "Morphophysiology of guava under saline water irrigation and nitrogen fertilization". Revista Brasileira de Engenharia Agrícola e Ambiental 22, n. 1 (gennaio 2018): 32–37. http://dx.doi.org/10.1590/1807-1929/agriambi.v22n1p32-37.
Testo completoAbstract (sommario):
ABSTRACT The aim of this study was to evaluate the growth of grafted guava cv. ‘Paluma’ subjected to different concentrations of salts in irrigation water and nitrogen (N) fertilization. The plants were transplanted to 150 L lysimeters and under field conditions at the Science and Agri-food Technology Center of the Federal University of Campina Grande, in the municipality of Pombal - PB. The experiment was conducted in randomized block design in a 5 x 4 factorial scheme, with three replicates, and the treatments corresponded to five levels of electrical conductivity of irrigation water - ECw (0.3; 1.1; 1.9; 2.7 and 3.5 dS m-1) and four N doses (70, 100, 130 and 160% of the N dose recommended for the crop). The doses equivalent to 100% corresponded to 541.1 mg of N dm-3 of soil. Irrigation water salinity above 0.3 dS m-1 negatively affects the number of leaves, leaf area, stem diameter, dry phytomass of leaves, branches and shoots . A significant interaction between irrigation water salinity and N fertilization was observed only for the number of leaves and leaf area at 120 days after transplanting. N dose above 70% of the recommendation (378.7 mg N dm-3 soil) did not mitigate the deleterious effects caused by salt stress on plant growth.
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Batool-Anwar, Salma, Candace Mayer, Patricia Haynes, Yilin Liu, Cynthia Thomson e Stuart Quan. "Impact of Recent Job Loss on Sleep, Energy Consumption and Diet". Southwest Journal of Pulmonary and Critical Care 23, n. 5 (16 novembre 2021): 129–37. http://dx.doi.org/10.13175/swjpcc045-21.
Testo completoAbstract (sommario):
To examine how sleep quality and sleep duration affect caloric intake among those experiencing involuntary job loss. Methods Adequate sleep and self-reported dietary recall data from the Assessing Daily Activity Patterns through Occupational Transitions (ADAPT) study was analyzed. Primary sleep indices used were total sleep time, time spent in bed after final awakening, and sleep quality as measured by the Daily Sleep Diary (DSD). Mean Energy consumption (MEC) was the primary nutritional index. Secondary indices included diet quality using the Health Eating Index 2015 (HEI), and self-reported intake of protein, carbohydrates and fats. Results The study participants were comprised mainly of women (61%) and non-Hispanic white. The participants had at least 2 years of college education and mean body mass index of 30.2±8.08 (kg/m 2 (). The average time in bed was 541.8 (9 hrs) ±77.55 minutes and total sleep time was 461.1 (7.7 hrs) ±56.49 minutes. Mean sleep efficiency was 91±6%, self-reported sleep quality was 2.40±0.57 (0-4 scale, 4 = very good), and minutes earlier than planned morning awakening were 14.36±24.15. Mean HEI score was 47.41±10.92. Although the MEC was below national average for both men and women, male sex was associated with higher MEC. In a fully adjusted model sleep quality was positively associated with MEC. Conclusion Daily overall assessments of sleep quality among recently unemployed persons were positively associated with mean energy consumption. Additionally, the diet quality of unemployed persons was found to unhealthier than the average American and consistent with the relationship between poor socioeconomic status and lower diet quality.
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Darambazar, Enkhjargal, Kathy Larson, Daalkhaijav Damiran e Herbert A. Lardner. "Evaluation of New Fall Rye Cultivar ‘Bono’ in Single and Double Cropping Systems". Agronomy 12, n. 6 (8 giugno 2022): 1382. http://dx.doi.org/10.3390/agronomy12061382.
Testo completoAbstract (sommario):
A new fall rye (FR, Secale cereale L.) cv. Bono was investigated as a novel cropping option in Saskatchewan, Canada. In this study, the performance of Bono was compared to Hazlet FR, and both cultivars were compared to winter triticale (WT, Triticosecale Wittm.) cv. Pika in single cropping (SC) or in double cropping (DC) systems with spring barley (Hordeum vulgare L.) was evaluated in the Dark Brown soil zone, 2019–2021. Five replicated (n = 4) treatments were: (i) BonoFR; (ii) HazletFR; (iii) PikaWT; (iv) Barley–BonoFR; and (v) Barley–HazletFR. The first crop of barley was harvested at soft dough stage, followed by the second crop of FR seeded in the same year and harvested between flag leaf to heading emergence the following summer for greenfeed hay. Bono did not differ (p > 0.05) in DMY (1.2 Mg ha−1) or nutritive value from Hazlet, however, both FRs differed (p = 0.01) from WT by higher nitrogen use efficiency (NUE, 41.0 vs. 33.7) and NDF (541.8 vs. 479.3 g kg–1), but lower CP (155.3 vs. 187.1 g kg–1). Double cropping barley with fall ryes increased total DMY, nutrients yield per ha, and minerals uptake by up to 83% and NUE by 35.3%. In conclusion, Bono fall rye could be an equal quality alternative to Hazlet, although the current higher seed price may delay its adoption.
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Bezerra, Idelfonso Leandro, Hans Raj Gheyi, Reginaldo Gomes Nobre, Geovani Soares de Lima, João Batista dos Santos e Pedro Dantas Fernandes. "Interaction between soil salinity and nitrogen on growth and gaseous exchanges in guava". Ambiente e Agua - An Interdisciplinary Journal of Applied Science 13, n. 3 (6 giugno 2018): 1. http://dx.doi.org/10.4136/ambi-agua.2130.
Testo completoAbstract (sommario):
This study evaluated the growth and gas exchanges of guava, cv. ‘Paluma’ cultivated in salinized soil and subjected to different nitrogen (N) doses in a protected environment in the municipality of Campina Grande-PB. The experimental design was randomized blocks, in a 5 x 4 factorial arrangement with three replicates, and the treatments resulted from the combination of five salinity levels in the soil saturation extract - ECse (2.15, 3.15,4.15, 5.15 and 6.15 dS m-1) and four N doses (70, 100, 130 and 160% of the recommended N dose). The dose referring to 100% of N corresponded to 541.1 mg of N dm-3 of soil. At 120 and 180 days after (DAT), plant growth was evaluated based on stem diameter (SD), leaf area (LA) and number of leaves (NL). At 210 DAT, the following variables of leaf gas exchanges were evaluated: stomatal conductance (gs), internal CO2 concentration (Ci), transpiration (E) and CO2 assimilation rate (A). ECse above 2.15 dS m-1 reduced stem diameter, leaf area, number of leaves, stomatal conductance, internal CO2 concentration, transpiration and CO2 assimilation rate, in both evaluation periods. N dose above 70% of the recommendation (378.7 mg N dm-3 of soil) did not mitigate the deleterious effects caused by the salt stress on the growth and gas exchanges of guava plants.
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Bezerra, Idelfonso Leandro, Hans Raj Gheyi, Reginaldo Gomes Nobre, Joicy Lima Barbosa, Reynaldo Teodoro de Fátima, Jutahy Jorge Elias, Leandro De Pádua Souza e Felipe Luenio de Azevedo. "Physiological alterations and production of guava under water salinity and nitrogen fertilizer application". Semina: Ciências Agrárias 39, n. 5 (20 settembre 2018): 1945. http://dx.doi.org/10.5433/1679-0359.2018v39n5p1945.
Testo completoAbstract (sommario):
Adequate management of saline water irrigation and nitrogen (N) fertilizer application in agriculture can contribute substantially to expanding guava cultivation in the semi-arid region of Northeast Brazil. This study aimed to evaluate gas exchange and production of ‘Paluma’ guava cultivated with different levels of water salinity and N. The experiment was carried out in drainage lysimeters under field conditions in an experimental area of the Federal University of Campina Grande (UFCG), Campus of Pombal, PB, Brazil. The experimental design was randomized blocks, in a 5 × 4 factorial scheme, with five levels of water salinity – ECw (0.3, 1.1, 1.9, 2.7 and 3.5 dS m-1) and four doses of N (70, 100, 130 and 160% of the recommendation) with three replicates. The dose relative to 100% corresponded to 541.1 mg of N dm-3 of soil. The following production components were evaluated: number of fruits, mean fruit weight, polar and equatorial diameter of fruits, and polar diameter/equatorial diameter ratio. In addition, the following physiological variables were evaluated at 180 days after fruit pruning: stomatal conductance, CO2 assimilation rate, internal CO2 concentration and transpiration rate. CO2 assimilation and transpiration rate were used to calculate instantaneous water use efficiency. The interaction between water salinity and N doses did not cause significant effects on any variable studied. Irrigation water salinity above 0.3 dS m-1 hampered gas exchange at 180 days after fruit pruning and negatively affected production components.
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O'Kelly, JC, e WG Spiers. "Metabolic effects of safflower oil given as a supplement for steers fed roughage diets at restricted intake". Australian Journal of Experimental Agriculture 30, n. 5 (1990): 585. http://dx.doi.org/10.1071/ea9900585.
Testo completoAbstract (sommario):
Supplements of safflower oil (300 mL/day) were given to groups of steers fed 4 different diets. Hereford steers were fed 6 kg/day lucerne hay (LH) or LH + 33 mg/kg monensin (LHM). Brahman steers were fed 4 kg/day low quality hay (DA) or DA + 1 kg sucrose + 60 g urea + 2.7 g sulfur (DAS). Metabolic measurements were made when the animals were fed an equal portion of the daily ration at hourly intervals. On all diets, safflower oil had no affect on rumen temperature, pH or the concentrations of volatile fatty acids in ruminal fluid. Safflower oil increased concentrations (mg/L) of microbial lipid in ruminal fluid (LH, 160.4 v. 317.1; LHM, 266 v. 541.7; DA, 194.6 v. 321.8; DAS, 172.8 v. 440.5) and increased plasma concentrations (�g/mL) of non-esterified fatty acids (LH, 117.2 v. 180.1; LHM, 101.1 v. 189.5; DA, 218.2 v 325.4; DAS, 197.4 v 311.4), especially 18:1 trans- 11 and polyunsaturated acids. In steers fed DA and DAS, safflower oil reduced protozoal numbers and increased the bacterial mass in ruminal fluid, and increased water intake and the daily amounts of urinary allantoin excreted. The addition of safflower oil to all diets depressed plasma urea concentrations (mg/L) (LH, 233 v. 203; LHM, 236 v. 191; DA, 74.6 v. 47.6; DAS, 96.6 v. 54). The excretion of daily amounts (mg/kg liveweight) of urinary urea increased in animals fed DA (3.5 v. 10.0) and DAS (6.2 v. 13.6) but decreased in those fed LH (208.8 v. 187.9) and LHM (188.8 v. 158.1). Safflower oil supplementation conserved body protein, accelerated liveweight gains in animals fed LH and LHM diets and retarded liveweight loss in those fed DA and DAS diets.
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Higgins, Simon, Michael V. Fedewa, Elizabeth D. Hathaway, Michael D. Schmidt e Ellen M. Evans. "Sprint interval and moderate-intensity cycling training differentially affect adiposity and aerobic capacity in overweight young-adult women". Applied Physiology, Nutrition, and Metabolism 41, n. 11 (novembre 2016): 1177–83. http://dx.doi.org/10.1139/apnm-2016-0240.
Testo completoAbstract (sommario):
The purpose of the study was to examine the effects of sprint interval training (SIT) and moderate-intensity continuous cycle training (MICT), with equal estimated energy expenditure during training on body composition and aerobic capacity. Body composition measured via dual-energy X-ray absorptiometry and aerobic capacity were assessed following 6 weeks of training in previously inactive overweight/obese young women (n = 52; age, 20.4 ± 1.5 years; body mass index, 30.3 ± 4.5 kg·m−2, 67.3% white). Training was performed in a group-exercise format that mimicked cycling classes offered by commercial fitness facilities, and included 3 weekly sessions of either 30-s “all-out” sprints followed by 4 min of active recovery (SIT), or continuous cycling at 60%–70% heart rate reserve to expend a similar amount of energy. Participants were randomized to SIT or MICT, attended a similar number of sessions (15.0 ± 1.5 sessions vs. 15.8 ± 1.9 sessions, P = 0.097) and expended a similar amount of energy (541.8 ± 104.6 kJ·session−1 vs. 553.5 ± 138.1 kJ·session−1, P = 0.250). Without significant changes in body mass (P > 0.05), greater relative reductions occurred in SIT than in MICT in total fat mass (3.6% ± 5.6% vs. 0.6% ± 3.9%, P = 0.007), and android fat mass (6.6% ± 6.9% vs. 0.7% ± 6.5%, P = 0.002). Aerobic capacity (mL·kg−1·min−1) increased significantly following both interventions (P < 0.05), but the relative increase was 2-fold greater in SIT than in MICT (14.09% ± 10.31% vs. 7.06% ± 7.81%, P < 0.001). In conclusion, sprint-interval cycling reduces adiposity and increases aerobic capacity more than continuous moderate-intensity cycling of equal estimated energy expenditure in overweight/obese young women.
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Bezerra, Idelfonso Leandro, Reginaldo Gomes Nobre, Hans Raj Gheyi, Geovani Soares De Lima e Joicy Lima Barbosa. "PHYSIOLOGICAL INDICES AND GROWTH OF ‘PALUMA’ GUAVA UNDER SALINE WATER IRRIGATION AND NITROGEN FERTIGATION". Revista Caatinga 31, n. 4 (dicembre 2018): 808–16. http://dx.doi.org/10.1590/1983-21252018v31n402rc.
Testo completoAbstract (sommario):
ABSTRACT The cultivation of irrigated guava in semi-arid areas highlights the need for information regarding its responses to irrigation water quality and the fertilization management that enables its exploitation. Thus, this study aimed to evaluate the effect of water salinity and nitrogen (N) doses on the growth and physiology of the guava cv. ‘Paluma’. The experiments was conducted in drainage lysimeters under field conditions in an experimental area at the Center of Sciences and Agri-Food Technology of the Federal University of Campina Grande (CCTA/UFCG), Campus II, in Pombal, PB, Brazil. The experiment had a randomized block design, and treatments consisted of a 5 x 4 factorial arrangement corresponding to five levels of irrigation water electrical conductivity, ECw (0.3, 1.1, 1.9, 2.7, and 3.5 dS m-1), and four N doses (70, 100, 130, and 160% of the recommended N dose). The 100% dose corresponded to 541.1 mg of N dm-3 of soil. Increments in irrigation water salinity from 0.3 dS m-1 led to a reduction in stomatal conductance, internal CO2 concentration, CO2 assimilation rate, transpiration, instantaneous water use efficiency, the number of leaves and branches, stem diameter, and absolute and relative growth rates. Nitrogen doses ranging from 378.7 to 865.7 mg of N dm-3 of soil did not affect gas exchange and plant growth. Although ‘Paluma’ guava growth was affected by increases in water salinity, these plants can be irrigated using water of up to 1.42 dS m-1 with an acceptable reduction of 10% in growth variables. The interaction between irrigation water salinity and N fertilization had no significant effect on any of the variables studied.
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Chung, Chanjong, Jinyoung Choi, Taeyoung Lee e Sangyoong Park. "The Effects of Intraoperative Remifentanil Infusion on Postoperative Opioid Consumption in Patients Who Underwent Total Knee Arthroplasty with Femoral Nerve Block". Journal of Clinical Medicine 12, n. 15 (28 luglio 2023): 4975. http://dx.doi.org/10.3390/jcm12154975.
Testo completoAbstract (sommario):
(1) Background: Remifentanil is used for intraoperative pain control; however, it has several side effects, such as hypotension and opioid-induced hyperalgesia. We aimed to determine whether an intraoperative remifentanil infusion may increase postoperative opioid consumption in patients undergoing total knee arthroscopy (TKA) under femoral nerve block (FNB) in addition to general anesthesia. (2) Methods: We randomly assigned 66 patients who underwent total knee arthroplasty to the remifentanil (R) and control (C) groups. All patients underwent FNB and popliteal artery and posterior capsule of the knee (iPACK) block in addition to sevoflurane-based general anesthesia. Postoperative pain control was achieved using intravenous patient-controlled analgesia (IV-PCA) fentanyl. We recorded IV-PCA fentanyl consumption at various postoperative timepoints, numerical rating scale (NRS) scores, intraoperative changes in vital signs and index of nociception (qNOX), ephedrine consumption, postoperative side effects, satisfaction, and sleep quality. (3) Results: The primary outcome (the cumulative IV-PCA fentanyl usage within 48 h postoperatively) was significantly lower in the C group (541.1 ± 294.5 µg) than in the R group (717.5 ± 224.0 µg) (p < 0.001). The secondary outcome (the cumulative IV-PCA fentanyl usage within 12, 24, and 72 h) was lower in the C group than in the R group and the mean arterial pressure was lower in the R group than in the C group from immediately after tourniquet on to immediately after tourniquet off. The heart rate was lower in the R group from immediately after incision to immediately after irrigation. There was no significant between-group difference in the perioperative qNOX and NRS scores at rest and activity except for NRS scores at 72 h postoperatively. Ephedrine use was higher in the R group than in the C group (p = 0.003). There was no significant between-group difference in the incidence of postoperative nausea and vomiting, nor in the postoperative satisfaction and sleep quality. (4) Conclusions: Avoiding intraoperative remifentanil infusion may reduce total opioid consumption in patients undergoing FNB before TKA.
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Hsu, Hsiao-Ching, e Wei-Ling Chen. "CPPU Improves Fruit Setting and Growth in Greenhouse-grown Oriental Melons (Cucumis melo L. var. makuwa Makino)". HortScience 59, n. 3 (marzo 2024): 340–47. http://dx.doi.org/10.21273/hortsci17594-23.
Testo completoAbstract (sommario):
The production of melons (Cucumis melo L.) in greenhouses relies on pollination. Extreme temperature and insufficient light reduce not only flower visitation by pollinators but also pollen viability, resulting in inefficient pollination. In this study, we investigated the effects of forchlorfenuron [(N-(2-chloro-4-pyridyl)-N′-phenylurea (CPPU)] on the fruit setting and growth of oriental melons (C. melo L. var. makuwa Makino). The primary objective was to devise a new strategy for the management of oriental melons. Treatment with 5 mg·L−1 CPPU a day before flowering (T1), on the day of flowering (T2), and a day after flowering (T3) increased the fruit setting rate (by 20.1% to 30%) in melons subjected to artificial pollination (AP) or no pollination (NP) compared with the rate in those subjected to only artificial pollination without CPPU (CK). CPPU treatment induced unfertilized seeds; in addition, a tendency toward parthenocarpy was noted. The highest fruit setting rate (∼95%) was noted in plants subjected to the following treatments: AP+T1 and NP+T3. The rates of abnormal fruit formation decreased from 45.2% of CK group to 9.4% in plants subjected to AP+T1 and to 19.4% in those subjected to NP+T3. Elevated exogenous concentrations of CPPU markedly increased fruit weight. Plants subjected to NP+10 mg·L−1 CPPU bore the heaviest fruits (541.0 g), which were heavier than those borne by plants subjected to AP+10 mg·L−1 CPPU. CPPU treatment reduced the fruit cavity ratio in a concentration-dependent manner from 47.3% to 33.6% and increased the pulp thickness from 1.5 to 2.5 cm. Notably, supplementary CPPU treatment exerted no significant effects on fruit traits. Regarding taste, inconsistent results were obtained for sugar accumulation. Although the content of cucurbitacin B increased immediately after the initial CPPU treatment, it markedly decreased after 15 days of CPPU treatment. Therefore, mature melons did not have a bitter taste.
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Gowd, Anirudh K., Joseph N. Liu, Brandon C. Cabarcas, Grant H. Garcia, Gregory L. Cvetanovich, Matthew T. Provencher e Nikhil N. Verma. "Management of Recurrent Anterior Shoulder Instability With Bipolar Bone Loss: A Systematic Review to Assess Critical Bone Loss Amounts". American Journal of Sports Medicine 47, n. 10 (27 agosto 2018): 2484–93. http://dx.doi.org/10.1177/0363546518791555.
Testo completoAbstract (sommario):
Background: There is increasing evidence to suggest that the amount of glenoid bone loss to indicate bone block procedures may be lower than previously thought, particularly in the presence of a Hill-Sachs defect. Purpose: To better establish treatment recommendations for anterior shoulder instability among patients with bipolar bone lesions. Study Design: Systematic review and meta-analysis; Level of evidence, 4. Methods: A systematic review of the literature was performed with PubMed, EMBASE, Cochrane Library, and Scopus databases according to PRISMA (Preferred Reporting Items for Systematic Reviews and Meta-analyses) guidelines. Studies evaluating outcomes of operative management in anterior shoulder instability that also reported glenoid bone loss in the presence of Hill-Sachs defects were included. Recurrence rates, glenoid bone loss, and humeral bone loss were pooled and analyzed with forest plots stratified by surgical procedure. Methods of quantification were analyzed for each article qualitatively. Results: Thirteen articles were included in the final analysis, with a total of 778 patients. The mean ± SD age was 24.9 ± 8.6 years. The mean follow-up was 30.1 months (range, 11-240 months). Only 13 of 408 (3.2%) reviewed bipolar bone loss articles quantified humeral and/or glenoid bone loss. Latarjet procedures had the greatest glenoid bone loss (21.7%; 95% CI, 14.8%-28.6%), followed by Bankart repairs (13.1%; 95% CI, 9.0%-17.2%), and remplissage (11.7%; 95% CI, 5.5%-18.0%). Humeral bone loss was primarily reported as percentage bone loss (22.2%; 95% CI, 13.1%-31.3% in Bankart repairs and 31.7%; 95% CI, 21.6%-41.1% in Latarjet) or as volumetric defects (439.1 mm3; 95% CI, 336.3-541.9 mm3 in Bankart repairs and 366.0 mm3; 95% CI, 258.4-475.4 mm3 in remplissage). Recurrence rates were as follows: Bankart repairs, 19.5% (95% CI, 14.5%-25.8%); remplissage, 4.4% (95% CI, 1.3%-14.0%); and Latarjet, 8.7% (95% CI, 5.0%-14.7%). Bankart repairs were associated with significantly greater recurrence of instability in included articles ( P = .013). Conclusion: There exists a need for universal and consistent preoperative measurement of humeral-sided bone loss. The presence of concomitant Hill-Sachs defects with glenoid pathology should warrant more aggressive operative management through use of bone block procedures. Previously established values of critical glenoid bone loss are not equally relevant in the presence of bipolar bone loss.
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Souza, Leandro de Pádua, Reginaldo Gomes Nobre, Evandro Manoel da Silva, Francisco Wesley Alves Pinheiro e Luana Lucas de Sá Almeida. "Crescimento de porta-enxerto de goiabeira sob águas salinizadas e doses de nitrogênio". Revista Verde de Agroecologia e Desenvolvimento Sustentável 10, n. 3 (29 settembre 2015): 53. http://dx.doi.org/10.18378/rvads.v10i3.3692.
Testo completoAbstract (sommario):
<p>A salinidade da água de irrigação pode afetar a exploração de cultivos principalmente nas regiões áridas e semiáridas, entretanto, algumas alternativas podem favorecer a exploração agrícola nestas condições. Desse modo, objetivou-se com este trabalho, avaliar a interação entre adubação nitrogenada e a salinidade da água de irrigação sob o crescimento de porta-enxerto de goiabeira ‘Crioula’ em condição de semiárido do nordeste do Brasil. O experimento foi conduzido em tubetes sob condições de ambiente protegido no CCTA/UFCG. Utilizou-se o delineamento experimental em blocos casualizados, com os tratamentos dispostos em esquema fatorial 5 x 4, correspondentes a cinco níveis de condutividade elétrica da água – CEa (0,3; 1,1; 1,9; 2,7 e 3,5 dS m<sup>-1</sup>) e quatro doses de nitrogênio (70, 100, 130 e 160% de N da dose recomendada para a cultura), com 4 repetições e 5 plantas por parcela. A dose de 70% de N (541,1 mg de N dm<sup>-1</sup> de solo) proporciona maior diâmetro de caule de porta-enxerto de goiabeira crioula aos 70 e 145 dias após a emergência (DAE), sobre a área foliar e altura de planta aos 145 DAE e na taxa de crescimento absoluto diâmetro do caule dos 25 a 145 DAE. A irrigação com água cuja salinidade era acima de 0,3 dS m<sup>-1</sup> afeta positivamente a razão de área foliar e de forma negativa, o número de folhas, a área foliar e o diâmetro do caule. Houve interação significativa entre os fatores adubação nitrogenada e salinidade da água de irrigação apenas para a variável número de folhas aos 145 DAE.</p><p><strong><em>Guava rootstocks growth in salted water and nitrogen levels</em></strong></p><pre><strong>Abstract: </strong>Salt stress suffered by plants due to concentration of irrigation water salts reduces the ability of exploitation of cultures especially in arid and semiarid regions. Thus, the aim of this study was to evaluate the effect of salinity of irrigation water on the growth of rootstock of guava 'Crioula' associated with increasing doses of nitrogen fertilizer. The experiment was conducted in plastic pots under greenhouse conditions in the CCTA / UFCG. We used the experimental randomized block design, with the treatments in a factorial 5 x 4, corresponding to five levels of electrical conductivity of the water - CEa (0.3; 1.1; 1.9; 2.7 and 3.5 dS m<span style="vertical-align: super;">-1</span>) and four nitrogen rates (70, 100, 130 and 160% of the recommended dose N for guava cultivation seedlings cv. Paluma) with 4 replications and 5 plants per plot. The dose of 70 % of N- ( 541.1 mg N dm<span style="vertical-align: super;">- 1</span> of soil ) provides greater production plant leaf area, height 145 DAE , but to stem diameter was significant in both periods studied the rootstock guava cv. Crioula. Irrigation CEa above 0.3 dS m<span style="vertical-align: super;">-1</span> negatively affect the number of leaves, leaf area, stem diameter, leaf area ratio and absolute growth rate of stem diameter. There was interaction between the factors salinity of irrigation water and nitrogen fertilization for variable number of leaves at 145 DAE rootstock of guava "Crioula".</pre>
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Ugurlu, S., B. H. Egeli, I. M. Bolayirli e H. Ozdogan. "AB0055 SOLUBLE TREM-1 LEVELS IN FAMILIAL MEDITERRANEAN FEVER RELATED AA-AMYLOIDOSIS". Annals of the Rheumatic Diseases 79, Suppl 1 (giugno 2020): 1329.2–1330. http://dx.doi.org/10.1136/annrheumdis-2020-eular.3426.
Testo completoAbstract (sommario):
Background:Triggering Receptor Expressed on Myeloid cells-1 (TREM-1) is a monocyte and neutrophil receptor functioning in innate immunity. TREM-1 produces proinflammatory cytokines and serves for neutrophil degranulation. TREM-1 activity is well known in the pathogenesis of sepsis; hence it can be also present in autoinflammatory diseases such as the most common monogenic one, Familial Mediterranean Fever (FMF).Objectives:The objective of this study is to measure soluble TREM-1 (sTREM-1) activity in severe FMF cases complicated with systemic AA-Amyloidosis.Methods:The cohort of the study includes regularly followed FMF related AA-Amyloidosis patients in a tertiary center outpatient rheumatology clinic. Soluble TREM-1 levels were measured using enzyme-linked immunosorbent assay (ELISA). In addition, demographic data, renal function tests, acute phase reactants, and medical prescription history was also noted and analyzed. None of the FMF diagnosed patients had an attack during the collection of the blood samples.Results:The patients were categorized into 4 groups: FMF related AA-Amyloidosis patients (A(+) FMF(+)), FMF unrelated AA-Amyloidosis (FMF(-) A(+)), FMF patients without Amyloidosis diagnosis (FMF(+) A (-)), and healthy controls (HC). The mean ages, TREM-1, C - reactive protein (CRP), and Creatinine levels of each group are shown in Table 1. TREM-1 levels were found to be significantly higher in A(+) FMF(+) group than FMF(+) A (-), and healthy control groups (p= 0.001 and 0.002). Nevertheless, this difference was not found in between A(+) FMF(+) and FMF(-) A(+) (p= 0.447). In addition, the TREM-1 levels of FMF(+) A (-), and healthy control groups were not different (0.532). In A(+) FMF(+) group, 36 patients used colchicine with the mean dose of 1.9±0.8 mg/day, 14 patients used anakinra, and 9 patients used canakinumab. In FMF(+) A (-) group all 20 patients used colchicine with the mean dose of 2.8±0.9 mg/day, 1 patient used anakinra, and 2 patients used canakinumab.Table 1.Clinical Features of Patients and TREM-1 levelsA(+) FMF(+)(n= 42)FMF(-) A(+)(n=5)FMF(+) A(-)(n=20)HC(n=20)Age43.9±12.954.8±1935.3±9.6435.4±6.57TREM-1735.3±566.51247.1±1349.2414.3±142.3439.2±104.6CRP11.1±14.251.3±98.325.8±541.8±1.7Creatinine1.6±1.83.28±4.170.7±0.150.7±0.15Conclusion:In conclusion, TREM-1 is a proinflammatory marker found significantly high in AA-amyloidosis patients regardless of their FMF diagnosis. TREM-1 may be useful in AA-amyloidosis follow-up and early diagnosis since currently there is a deficit of an early diagnostic marker of amyloidosis. This study is a cross-sectional one so it is hard to reach a conclusion on the effectiveness of TREM-1 during regular FMF follow-up for the secondary prevention of amyloidosis. However, the sensitivity of TREM-1 as a marker cannot be denied in amyloidosis.Disclosure of Interests:None declared
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KLYMOV, Yulii. "STRENGTH OF BUTT WELDED BUTT JOINT OF REINFORCEMENT OF CLASS A500C". Building constructions. Theory and Practice, n. 11 (26 dicembre 2022): 4–17. http://dx.doi.org/10.32347/2522-4182.11.2022.4-17.
Testo completoAbstract (sommario):
The paper presents the results of experimental studies of the strength of cross-shaped welded joints of types К1-Кт and К3-Рр [1] of thermomechanically hardened reinforcement of class A500C [2] for hardening during welding of the main bar [3].
Experimental studies included testing three series of samples of welded joints and reinforcement samples in the initial state. The first series included testing welded joints of type К1-Кт to strengthen the main bar during welding. Reinforcement Ø14A500С was accepted as the main (working) bar, and reinforcement Ø12A500С and Ø8A240С were accepted as the transverse bar. For each joints, 6 samples were tested on the lower and upper limits of the carbon equivalent values of the grade steel class Ст3пс, 0.245% and 0.346%, respectively. The second series included testing of welded joints of the K3-Pp type to strengthen the main bar during welding. To directly compare the test results of different types of cross-shaped welded joints, the diameter of the main and transverse rods, the number of samples and the value of equivalent were the same as in the first series. The third series included testing welded joints of type К1-Кт for cutting. Reinforcement Ø14A500С was taken as a longitudinal bar, and reinforcement Ø12A500С and Ø8A500С was taken as a transverse rod. For each joints, 12 samples were tested at the lower and upper limits of the carbon equivalent values.
As a result of testing samples of welded joints of types К1-Кт and К3-Рр of reinforcement A500C for strengthening during welding, it was established that the destruction occurs along the main bar and in the zone of thermal exposure, the amount of hardening was up to 4% for the К1-Кт compound, and for the К3-Рр type connection - 4... 10%.
Failure of samples of welded joints of type К1-Кт reinforcement A500C with reinforcement Ø12A500C and Ø8A240C during the cut test usually occurred in the zone of thermal exposure, or in some cases, in the presence of both rods from reinforcement of class A500C - directly at the welding site. The average value of cut strength for a sample of 24 samples of reinforcement connections of class A500C with reinforcement A240C was 356.5 MPa, or 0.89 of the temporary resistance of the reinforcement in the initial state, with a coefficient of variation - 0.08 and a span of 107.4 MPa. The average cut strength for a sample of 24 samples of reinforcement connections of class A500C with reinforcement A500C was 541.1 MPa, or 0.80 of the temporary resistance of the reinforcement in the initial state, with a coefficient of variation – 0.152 and a span of 280.0 MPa.
The first series included fittings Ø12A500C, Ø14A500C, Ø16A500C from steel of the ST3ps brand and Ø18A500C, Ø20A500C, Ø22A500C from steel of the Ст3пс brand. A total of 278 samples of welded joints were tested. The second series included samples of C1-Co welded joints from the rest of the nomenclature of diameters and grades of steel reinforcement class A500C, namely Ø16A500C from steel grade St3ps, Ø20A500C, Ø22A500C from steel grade St3Gps and Ø25A500C, Ø32A500C, Ø32A500C, Ø32A500C. For each of the diameters, 6 samples were tested in the initial state and 6 samples of C1-Co welded joints.
It was found that the destruction of the butt contact connection type C1-Co thermomechanically reinforced reinforcement class A500C of all diameters, from 12 to 32 mm, and steel grades, takes place in the zone of thermal impact and is plastic.
Experimental data on the strength of the butt contact weld type C1-Кo reinforcement class A500C for the entire range of diameters and grades of steel produced in Ukraine. It is established that the greatest degree of hardening within 19-20% takes place at diameters of armature of 12… 16 mm from steel of the Ст3пс brand, at diameters of armature of 18… 22 mm from steel of the Ст3Гпс brand of marking made 15-17%, and at diameters of 25… 32 mm from steel of the 25Г2С brand - 2,5… 8%.
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Bodard, Sylvain, Sylvain Guinebert, Elena N. Petre, Erica Alexander, Brett Marinelli, Debkumar Sarkar e Francois H. Cornelis. "Percutaneous Lung Biopsies With Robotic Systems: A Systematic Review of Available Clinical Solutions". Canadian Association of Radiologists Journal, 6 aprile 2024. http://dx.doi.org/10.1177/08465371241242758.
Testo completoAbstract (sommario):
Objectives: This systematic review aims to assess existing research concerning the use of robotic systems to execute percutaneous lung biopsy. Methods: A systematic review was performed and identified 4 studies involving robotic systems used for lung biopsy. Outcomes assessed were operation time, radiation dose to patients and operators, technical success rate, diagnostic yield, and complication rate. Results: One hundred and thirteen robot-guided percutaneous lung biopsies were included. Technical success and diagnostic yield were close to 100%, comparable to manual procedures. Technical accuracy, illustrated by needle positioning, showed less frequent needle adjustments in robotic guidance than in manual guidance ( P < .001): 2.7 ± 2.6 (range 1-4) versus 6 ± 4 (range 2-12). Procedure time ranged from comparable to reduced by 35% on average (20.1 ± 11.3 minutes vs 31.4 ± 10.2 minutes, P = .001) compared to manual procedures. Patient irradiation ranged from comparable to reduced by an average of 40% (324 ± 114.5 mGy vs 541.2 ± 446.8 mGy, P = .001). There was no significant difference in reported complications between manual biopsy and biopsies that utilized robotic guidance. Conclusion: Robotic systems demonstrate promising results for percutaneous lung biopsy. These devices provide adequate accuracy in probe placement and could both reduce procedural duration and mitigate radiation exposure to patients and practitioners. However, this review underscores the need for larger, controlled trials to validate and extend these findings.
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Rodrigues-Filho, R. A., R. G. Nobre, A. S. Santos, A. D. S. Teixeira, A. P. N. Ferreira, L. A. A. Soares, G. S. Lima et al. "Morphology of ‘Crioula’ guava seedlings under irrigation with increasing salinity water and nitrogen/potassium fertilization". Brazilian Journal of Biology 83 (2023). http://dx.doi.org/10.1590/1519-6984.275322.
Testo completoAbstract (sommario):
Abstract Several studies have been conducted evaluating the management of fertilizers as strategies to mitigate the deleterious effects of salt stress, so the objective of this work was to evaluate the quality of ‘Crioula’ guava seedlings under irrigation with water of different salinity levels and fertilized with combinations of nitrogen and potassium. The experiment was performed in a protected (screened) environment using a randomized block design and analyzed in a 5 × 4 factorial scheme, with four replicates, with the plot formed by two plants. The treatments were formed from the combination of the factor electrical conductivity of irrigation water (ECw 0.3, 1.1, 1.9, 2.7 and 3.5 dS m-1), with the factor combinations (C) of nitrogen (N) and potassium (K2O) doses, being C1 = 70% N + 50% K2O, C2 = 100% N + 75% K2O, C3= 130% N + 100% K2O and C4= 160% N + 125% K2O. The recommended dose of 100% N and K, respectively, was 541.1 mg N dm-3 soil and 798.6 mg K dm-3 soil. The combinations of N and K fertilization corresponding to 70% N + 50% K2O and 100% N + 75% K2O of the recommended doses promoted greater growth of ‘Crioula’ guava seedlings. Water with ECw of 2.1 dS m-1 promotes the formation of quality ‘Crioula’ guava seedlings.
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Rahman, Aminur, Muhammad Jamil Ahmed, Abul Hasnat Russel, Mohammed Nazmul Huq e Zahed Ali. "The Role of Plasma D-dimer As An Initial Diagnostic Biomarker of Cerebral Venous Sinus Thrombosis In A Tertiary Level Hospital, Bangladesh – Case Control Study". Bangladesh Journal of Medicine, 24 maggio 2023, 202–3. http://dx.doi.org/10.3329/bjm.v34i20.66158.
Testo completoAbstract (sommario):
Background: Cerebral venous sinus thrombosis (CVST) are an uncommon cause of stroke and is often more difficult to diagnose than usual causes of stroke.A number of studies have confirmed the usefulness of Ddimer level in CVST. The aim of the current study to evaluate the correlation of plasma D-dimer levels in diagnosis of CVST. Methods: This case-control study was conducted on 50 stroke patients and 50 healthy individuals as the control group who will attend in the Department of Neurology of Sir Salimullah Medical College & Mitford Hospital, Dhaka Bangladesh during one year (2021-2022) with new onset headache and presentations suggestive of CSVT will be included in the study. Every medical or surgical condition which causes an increase in D-dimer level was considered as exclusion criteria. Results: Among patient group, 28(56%) patients were females, while 22(44%) patients were males, and the mean of age was 37.7±11.8 years. Headache was the most frequent presentation that observed in 90% of the patients. The patient with focal neurological signs, papilloedema and seizures came next in 52%, 44% and 30% respectively. The average duration of the symptoms was 6.9 ±3.2 days. Overall, the mean plasma level of D-dimer in CVST patients and controls were 526.7± 97.34 ng/mL and 332.3± 53.71 ng/mL respectively (Table: 3). Independent t-test revealed a significant difference (t= 2.167, p= 0.029). According to cut-off value of the assay (400 ng/mL) there were 44 CVST patients (88%) who were positive for the test compared with 7 (14%) among controls (p< 0.001). Stratification of the study population according to male revealed a wide gap between patient and control males (541.7± 114.9 ng/mL and 320.2±71.13 ng/mL respectively) with a significant difference (p= 0.017) (Table: 4). However, in females, this gap was narrower (530.4± 100.9 ng/mL in females with CVST and 349.7±92.5 ng/ mL in healthy females) but still significant (p= 0.032). The test revealed that the area under the curve (AUC) was 0.879, 95%CI=0.807-0.95, p<0.001. The sensitivity and specificity of the test at cut off value of 400ng/ mL were 0.88 and 0.86 respectively, indicating a very good discrimination value. The positive and negative predictive values of D-dimer in diagnosis of CVST were 86.27 % and 87.76% respectively. Conclusion: Our study suggests that measurement of D-dimer can be a reliable tool for diagnosis of CVST, especially in patients with acute and subacute disease. Bangladesh J Medicine 2023; Vol. 34, No. 2(1) Supplement: 202-203
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David, Karel, Nick Narinx, Jetty De Loor, Leen Antonio, Dirk Vanderschueren, Frank Claessens, Brigitte Decallonne e Pieter Evenepoel. "#4184 MALE CHRONIC KIDNEY DISEASE IS A STATE OF PREMATURE TESTICULAR AGING". Nephrology Dialysis Transplantation 38, Supplement_1 (giugno 2023). http://dx.doi.org/10.1093/ndt/gfad063c_4184.
Testo completoAbstract (sommario):
Abstract Background and Aims Sex steroid levels have been reported to be decreased in male patients with chronic kidney disease (CKD), parallel to the severity of the kidney dysfunction. These studies, at large, used immuno-assays, a method that is inferior to gold standard chromatography measurements and, in addition, failed to give insights into the underlying pathophysiology as they lacked data on gonadotropin levels. The aim of this study was to comprehensively map the gonadal status in male CKD patients not yet on dialysis and age- and BMI-matched controls, using gold standard techniques. Method We performed a case-control study in 120 male CKD patients (age 65.0 y, BMI 26.8 kg/m2), matched (1:1) with non-CKD controls for age and BMI. We divided CKD patients into 3 categories based on KDIGO classification: CKD 1–2 (n = 24), CKD 3 (n = 42) and CKD 4–5 (n = 54). We measured total testosterone (T) and estradiol (E2) using liquid chromatography tandem mass-spectrometry. Sex hormone binding globulin (SHBG), prolactin, luteinizing hormone (LH) and follicle stimulating hormone (FSH) were measured on the Roche Cobas 8000 platform. Free T levels were calculated via Vermeulen formula. Inhibin B (a readout for testicular Sertoli cell function) was measured by ELISA. Results CKD patients showed lower total T (426.0 ng/dL [297.5-516.5] vs. 541.0 ng/dL [452.0-647.8]; p<0.0001) and free T levels (7.4 ng/dL ±3.2 vs. 9.4 ng/dL +/-2.2; p<0.0001) as compared to non-CKD counterparts. SHBG and E2 levels, conversely, were comparable in cases and controls. Inhibin B levels were lower in CKD patients as well (112.7 pg/mL [38.1-189.0] vs. 181.1 [122.2-236.4]; p<0.0001). LH and FSH levels were higher in CKD patients (9.1 IU/L [5.4-16.2] vs. 5.4 IU/L [3.6-8.1]; p<0.0001 and 7.8 IU/L [5.0-20.2] vs. 5.6 IU/L [4.0-9.7]; p<0.0001 respectively). Consequently, the T/LH ratio and inhibin B/FSH ratio, respectively reflecting Leydig and Sertoli cell function, were markedly depressed in CKD (1.8 nmol/IU [0.7-3.0] vs. 4.0 nmol/IU [2.4-5.2]; p<0.0001 and 14.4 ng/IU [1.2-33.6] vs. 32.2 ng/IU [32.2 [16.3-56.7]; p<0.0001). In the CKD cohort, regression analysis identified eGFR and age as independent determinants of T/LH ratio (R2 0.29). According to the T/LH ratio a male CKD patient of 45y old has a testicular age of an 81y old control. Conclusion Male patients with CKD not yet on dialysis show low total and free T levels, confirming CKD as a risk factor for male hypogonadism. The low T/LH and inhibin B/FSH ratio point to testicular failure as the underlying pathophysiological mechanism.
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Costa, Claudia, Nadiesda Peres, Carolina Branco, Bernardo Silva, José Agapito Fonseca, Cristina Outerelo, Cristina Resina, José António Lopes e Joana Gameiro. "#6242 CLINICAL CHARACTERISTICS OF HEMODIALYSIS PATIENTS FROM AFRICAN COUNTRIES OF PORTUGUESE OFFICIAL LANGUAGE: A PORTUGUESE COHORT". Nephrology Dialysis Transplantation 38, Supplement_1 (giugno 2023). http://dx.doi.org/10.1093/ndt/gfad063c_6242.
Testo completoAbstract (sommario):
Abstract Background and Aims Chronic kidney disease (CKD) is a leading cause of morbidity and mortality worldwide, with African descendants being at increased risk of occurrence and progression to end-stage renal disease (ESRD). However, the burden of CKD and ESRD in African continent is still largely conjectural and access to treatment of CKD is restricted in those countries. Africa contributes to <10% of the total renal replacement therapy (RRT) patients worldwide, mainly due to the high costs associated. The purpose of this analysis was to describe the clinical characteristics and outcomes of patients from African Countries of Portuguese Official Language (ACPOL) who integrated the HD program of a tertiary hospital in Portugal. Method Retrospective analysis of 126 African patients who integrated the HD program of a tertiary hospital in Portugal, between January 2015 and December 2019. Last follow-up was ascertained in January 2021. Results Mean age was 49.9 ± 14.1 years, and 53.6% were male (n = 71). Hypertension was a comorbidity in 96.0% (n = 121). Twenty-one patients came from Angola (16.7%), 53 from Cape Verde (42.1%), 23 from Guinea-Bissau (18.3%), 20 from Saint Thomas and Prince (15.9%), and 9 from Mozambique (7.1%). Motive for referral to Portugal was RRT requirement in 93.7% of the cases (n = 118) and vascular access (VA) dysfunction in 6.3% (n = 8); these 8 patients with VA dysfunction were already on hemodialysis program before their evacuation to Portugal and they were mainly from Cape Verde (n = 4), Angola (n = 3), and one patient from Guinea-Bissau. At arrival, patients who initiated HD in our unit had mean serum creatinine 9.4 ± 4.4 mg/dL, urea 182.5 ± 109.1 mg/dL, Hb 9.6 ± 1.7 g/dL, serum albumin 3.6 ± 0.6 g/dL, PTH 491.7 ± 392.6 pg/mL. Patients referred due to VA dysfunction had mean Hb 10.1 ± 1.8 g/dL, serum albumin 3.7 ± 1.0 g/dL, PTH 918.9 ± 541.6 pg/mL. There were no statistically significant differences in both groups concerning country of origin, although hypoalbuminemia was more frequent in patients from Saint Thomas and Prince (50%) and Angola (42.9%). All patients started HD with a central venous catheter (CVC). During follow-up, CVC remained the vascular access in 51.6% (n = 65), arteriovenous fistula in 42.9% (n = 54), and arteriovenous graft in 5.6% patients (n = 7). Nine patients had exhaustion of VA for HD. Mean follow-up time was 70.5 ± 41.3 months, 1.6% of the patients transitioned to peritoneal dialysis (n = 2) and 15.1% were submitted to renal transplantation (n = 18). The mortality rate during follow-up was 14.3% (n = 18). Conclusion There are few studies about African patients undergoing HD and this is the first study presenting the clinical characteristics and outcomes of hemodialysis patients from ACPOL. These are young patients, almost all with hypertension, with a high prevalence of anemia, malnutrition, and secondary hyperparathyroidism. All patients started HD with CVC and several presented multiple access dysfunction. These data reinforce the urgent need of improvement and investment in African countries’ healthcare, especially on what concerns the ESRD, as it contributes to serious consequences in these patients’ survival and quality of life. With the cooperation protocol, Portugal provides these patients with RRT, treatment of the CKD complications, VA care, possibility of peritoneal dialysis and renal transplantation, ultimately improving their chance of survival and quality of life.
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Bai, Jennifer, Sarah Ferenz, Megan Fracol e John Y. S. Kim. "A Comparison of Capsular Contracture Rates after Implant-Based Breast Reconstruction Using ADM Versus Synthetic Mesh". Aesthetic Surgery Journal Open Forum 6, Supplement_1 (12 aprile 2024). http://dx.doi.org/10.1093/asjof/ojae007.018.
Testo completoAbstract (sommario):
Abstract Goals/Purpose Capsular contracture is a local complication in which there is tightening of the capsule around the implant. This complication has been shown to occur in 15-30% of implant-based breast reconstruction patients and often requires revision surgery for correction. Prior investigations have suggested that the use of ADM can reduce the risk for development of capsular contracture, with more recent research suggesting that synthetic mesh may provide the same benefit. Several meta-analyses have attempted to compare ADM and mesh use for the prevention of capsular contracture, but they all emphasize the continued need for clinical investigation with direct comparisons. The goal of this study is to assess our own reconstruction patient population to compare capsular contracture rates between ADM and mesh cohorts, as well as to assess for other potential risks that may increase the rate of capsular contracture in these patients. Methods/Technique A 15-year retrospective review of all implant-based breast reconstructions performed by the senior author was performed. All operations occurred between 2008 and 2023 in a hospital setting. Patient demographics were assessed including age, BMI, implant size, radiation history, location of malposition, and use of either ADM or mesh. Post-operative complications including incidence of capsular contracture were recorded. Patients who had documented capsular contracture prior to scaffold insertion were excluded from the study. Wilcoxon signed rank test, 2-sided t-test, and Fischer’s Exact test were used to compare baseline demographics and capsular contracture rates between the two groups, along with a multivariate logistic regression analysis to control for potential confounders. Results/Complications Fifty-two breasts underwent capsulorraphy, of which 25 (48.1%) used ADM and 27 (51.9%) used mesh. Average age was 50.6 years, average BMI was 27.7, average implant size was 541.8 cc, and eight breasts (15.4%) had been irradiated. Average follow-up time was seven years (mean = 85.4 months, range 22 – 149 months, SD = 35.9). Fourteen (26.9%) capsulorraphies were for inferior malposition, 13 (25.0%) for lateral malposition, and 25 (48.1%) were for inferolateral malposition. Patients in the ADM group had significantly more lateral malposition prior to insertion as compared to the mesh group which had more inferior malposition (p=0.0246). There was no significant difference between the two groups for any other recorded baseline demographic; these demographics included age, BMI, hypertension, diabetes, history of tobacco use, radiation, chemotherapy, implant volume, and implant surface texture. Capsular contracture occurred in 2 ADM breasts (8.0%) and 4 mesh breasts (14.8%) with no significant difference between the two groups (p=0.6695). Five of these capsular contractures had documented Baker grades with three grade II, one grade III, and one grade IV. None of the recorded baseline demographics significantly increased the risk for capsular contracture development. Conclusion ADM and synthetic mesh both function as effective tools for reducing the risk of developing capsular contracture after prosthetic breast reconstruction. The rate of capsular contracture with ADM was only 8.0% and the rate with mesh was only 14.8%. Both rates are lower than the 15-30% incidence that has been found in breast reconstruction patients without mesh. None of the patient demographics were significant risk factors for capsular contracture development, so these are unlikely to be confounders. There was no significant difference in rate of capsular contracture between the two groups, suggesting that ADM and mesh are similarly efficacious at preventing capsular contracture in reconstruction patients.