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Letteratura scientifica selezionata sul tema "2003 i-838"

Autore: Grafiati

Pubblicato: 26 luglio 2024

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Articoli di riviste sul tema "2003 i-838"

1

Pich Mitjana, Josep, and David Martínez Fiol. "Manuel Brabo Portillo. Policía, espía y pistolero (1876-1919)." Vínculos de Historia. Revista del Departamento de Historia de la Universidad de Castilla-La Mancha, no. 8 (June 20, 2019): 387. http://dx.doi.org/10.18239/vdh_2019.08.20.

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RESUMEN:El objetivo del artículo es aproximarnos a la controvertida biografía del comisario Manuel Brabo Portillo. El trabajo está basado en fuentes primarias y secundarias. El método utilizado es empírico. En el imaginario del mundo sindicalista revolucionario, Brabo Portillo era el policía más odiado, la reencarnación de la cara más turbia del Estado. Fue, así mismo, un espía alemán relacionado con el hundimiento de barcos españoles, el asesinato del empresario e ingeniero Barret y el primer jefe de los terroristas vinculados a la patronal barcelonesa. La conflictividad que afectó a España e

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2

Li, Yinkui, Xiaoxiao Qin, Wen Li, Xiaoling Wang, and Haicheng Ma. "Connected even factors in k-tree." Open Mathematics 18, no. 1 (2020): 1601–5. http://dx.doi.org/10.1515/math-2020-0106.

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Abstract (sommario):

Abstract A connected even {[}2,2s] -factor of a graph G is a connected factor with all vertices of degree i(i=2,4,\ldots ,2s) , where s\ge 1 is an integer. In this paper, we show that a \tfrac{k+1}{s+2} -tough k-tree has a connected even {[}2,2s] -factor and thereby generalize the result that a \tfrac{k+1}{3} -tough k-tree is Hamiltonian in [Hajo Broersma, Liming Xiong, and Kiyoshi Yoshimoto, Toughness and hamiltonicity in k-trees, Discrete Math. 307 (2007), 832–838].

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3

Li, Yinkui, Xiaoxiao Qin, Wen Li, Xiaoling Wang, and Haicheng Ma. "Connected even factors in k-tree." Open Mathematics 18, no. 1 (2020): 1601–5. http://dx.doi.org/10.1515/math-2020-0106.

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Abstract (sommario):

Abstract A connected even [ 2 , 2 s ] {[}2,2s] -factor of a graph G is a connected factor with all vertices of degree i ( i = 2 , 4 , … , 2 s ) i(i=2,4,\ldots ,2s) , where s ≥ 1 s\ge 1 is an integer. In this paper, we show that a k + 1 s + 2 \tfrac{k+1}{s+2} -tough k-tree has a connected even [ 2 , 2 s ] {[}2,2s] -factor and thereby generalize the result that a k + 1 3 \tfrac{k+1}{3} -tough k-tree is Hamiltonian in [Hajo Broersma, Liming Xiong, and Kiyoshi Yoshimoto, Toughness and hamiltonicity in k-trees, Discrete Math. 307 (2007), 832–838].

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4

Stock, Wendy, Ben Sanford, Gerard Lozanski, et al. "Alemtuzumab can be Incorporated Into Front-Line Therapy of Adult Acute Lymphoblastic Leukemia (ALL): Final Phase I Results of a Cancer and Leukemia Group B Study (CALGB 10102)." Blood 114, no. 22 (2009): 838. http://dx.doi.org/10.1182/blood.v114.22.838.838.

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Abstract Abstract 838 Eradication of minimal residual disease (MRD) during the first months of ALL treatment is associated with improved disease-free survival (DFS). We hypothesized that alemtuzumab, a humanized anti-CD52 monoclonal antibody, might be an effective, novel agent for eradication of MRD. In CALGB 10102, we tested dose escalation of alemtuzumab in sequential cohorts of CD52+ cases to a target dose of 30 mg administered SC 3 times/week for 4 weeks (12 doses) during post-remission therapy. Dose limiting toxicity (DLT) was defined as the inability to proceed with protocol treatment wi

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5

Kushner, James P., Michael R. Franklin, Christopher P. Reilly, Hector A. Bergonia, and John D. Phillips. "An Inhibitor of Uroporphyrinogen Decarboxylase (URO-D) Causes Porphyria Cutanea Tarda (PCT)." Blood 108, no. 11 (2006): 270. http://dx.doi.org/10.1182/blood.v108.11.270.270.

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Abstract Hepatic iron content is increased in patients with PCT and phlebotomy-induced iron depletion corrects the clinical and biochemical phenotype. Approximately 20 percent of patients with PCT are homozygous for mutations of the hemochromatosis gene (HFE) but the cause of iron overload in most patients is unknown. Hepatic URO-D activity is markedly reduced when PCT is manifest and URO-D activity improves following iron depletion. Most patients with PCT have no mutations of the URO-D gene (sporadic PCT) but approximately 1/3 of cases are heterozygous for URO-D mutations (familial PCT) (BLOO

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6

De Los Ríos, José F., Juan D. Castañeda, Gustavo A. Calle, et al. "Histerectomía laparoscópica total en la unidad de endoscopia ginecológica de la Clínica del prado, Medellín (Colombia) 2002 - 2008." Revista Colombiana de Obstetricia y Ginecología 60, no. 4 (2009): 320–27. http://dx.doi.org/10.18597/rcog.314.

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Objetivo: describir la experiencia en la práctica de Histerectomía Laparoscópica Total (HLT) con énfasis en las complicaciones presentadas.Metodología: el presente es un estudio de cohorte histórica en el cual se incluyeron las pacientes que fueron intervenidas entre diciembre de 2002 y abril de 2008 y en quienes, además, se completó al menos 90% de la información requerida en un formulario prediseñado. Durante la investigación, se evaluaron las características sociodemográficas, las indicaciones de cirugía, el porcentaje de laparoconversión y las causas de la misma, el tiempo quirúrgico, la p

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7

Marinkovic, Smiljana, Svetlana Bukarica, Mihajlo Jeckovic, Svetlana Skoric, Jelena Antic, and Zvezdana Starcevic. "Ultrasound-guided water enema for reduction of childhood intussusception." Medical review 60, no. 11-12 (2007): 605–9. http://dx.doi.org/10.2298/mpns0712605m.

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Abstract (sommario):

Introduction. Intussusception is a common abdominal emergency in infants and children. Ultrasonography and barium enema are very useful in diagnosis and treatment of this condition. The aim of the study was to assess the accuracy of ultrasound-guided saline enema for intussusception and to determine if some factors may improve the outcome of this technique. Material and methods. Intussusception was diagnosed in 63 patients at the Clinic of Pediatric Surgery in Novi Sad. The study period was divided into two 2-year phases: phase I, from 2001 through 2002, and phase II, from 2003 through 2004. D

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8

Vergote, Ignace B., Florence Joly, Dionyssios Katsaros, et al. "Randomized phase III study of erlotinib versus observation in patients with no evidence of disease progression after first-line platin-based chemotherapy for ovarian carcinoma: A GCIG and EORTC-GCG study." Journal of Clinical Oncology 30, no. 18_suppl (2012): LBA5000. http://dx.doi.org/10.1200/jco.2012.30.18_suppl.lba5000.

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Abstract (sommario):

LBA5000 Background: The epidermal growth factor receptor (EGFR) has been found to be overexpressed in 55-98% of advanced epithelial ovarian cancer. This trial evaluated the efficacy of maintenance erlotinib, an EGFR tyrosine kinase inhibitor, after first-line chemotherapy. Methods: Eligible patients (pts) had high-risk FIGO stage I or stage II-IV epithelial ovarian, peritoneal or fallopian tube cancer and were not selected for EGFR expression. All patients underwent first line therapy (6-9 cycles of 3-weekly platinum-based chemotherapy (CT)) and showed no signs of progression at the end of CT.

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9

Peelen, E., A. Muehler, D. Vitt, and H. Kohlhof. "P064 IMU-838, a Small Molecule DHODH Inhibitor in Phase 2 Clinical Trial for Ulcerative Colitis, Shows Potent Anti-inflammatory Activity in Cell-Culture-Based and In Vivo Systems." Journal of Crohn's and Colitis 16, Supplement_1 (2022): i172—i173. http://dx.doi.org/10.1093/ecco-jcc/jjab232.193.

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Abstract Background IMU-838 (vidofludimus calcium) is a well-tolerated and orally available small molecule inhibitor of dihydroorotate dehydrogenase (DHODH) and is currently in phase 2 clinical development for ulcerative colitis (UC). Here, we investigated the effect of IMU-838 on different immune cell subsets and analysed the mechanism of action in more detail in T cells. Methods The effect of IMU-838 on regulatory macrophages (Mregs) was investigated by adding IMU-838 or anti-TNFα antibodies (infliximab, adalimumab), alone or in combination, in a mixed lymphocyte reaction assay, determining

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10

Olivier, C. Y., G. Séguin-Swartz, D. Hegedus, and T. Barasubiye. "First Report of “Candidatus Phytoplasma asteris”-Related Strains in Brassica rapa in Saskatchewan, Canada." Plant Disease 90, no. 6 (2006): 832. http://dx.doi.org/10.1094/pd-90-0832c.

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“Candidatus phytoplasma asteris” and related strains (i.e., aster yellows group 16SrI) have been associated with diseases of numerous plant species worldwide. Symptoms of aster yellows (AY) have been reported on rapeseed/canola (Brassica napus and B. rapa) crops in Saskatchewan (SK) and Manitoba, Canada since 1953 (2). Symptoms generally include stunting, virescence, leaf yellowing or purpling, phyllody, and formation of bladder-like siliques. A total of 120 mature B. rapa cv. AC Sunbeam plants exhibiting AY symptoms were collected in commercial fields near Medstead, SK during 2003 and 2004 (o

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