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Littérature scientifique sur le sujet « Xenopus laevi »

Auteur : Grafiati

Publié le 9 mars 2023

Mis à jour le 10 mars 2023

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Articles de revues sur le sujet "Xenopus laevi"

Munck, B. G., and L. K. Munck. "Na+-independent transport of bipolar and cationic amino acids across the luminal membrane of the small intestine." American Journal of Physiology-Regulatory, Integrative and Comparative Physiology 272, no. 4 (1997): R1060—R1068. http://dx.doi.org/10.1152/ajpregu.1997.272.4.r1060.

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The role of sodium in transport of bipolar and cationic amino acids and their interactions were examined in vitro by measuring unidirectional influx across the brush-border membrane of intact rat jejunal and rabbit ileal epithelia. The chloride-dependent and beta-alanine inhibitable B(0,+) present in rabbit ileum was blocked by combining inhibition by beta-alanine with Na(+)- or Cl(-)-free conditions. Under these conditions, lysine influx across the brush-border membrane is Na+ independent. All Na+-independent influx of cationic and bipolar amino acids is by a system b(0,+) equivalent in the brush-border membrane of both species, where a system y+ is not present. System b(0,+) is shown to be a potent exchanger of intracellular leucine for extracellular lysine and of intracellular lysine for extracellular leucine. The model used to explain leucine stimulation of mucosa to serosa lysine transport can explain Na+ dependence of net lysine absorption. On the assumption that b(0,+) in situ, like the transporter induced by retroperitoneal brown adipose tissue in Xenopus laevi oocytes, acts as an obligatory exchanger, this model can also explain the effects of lysine on short-circuit current and net transport of sodium and the effect on transport capacity by preincubation at Na+-free conditions.

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Liu, Xia, Xue-mei Ji, Xi-ning Du, et al. "Molecular Cloning, Expression, Bioinformatics Analysis, and Bioactivity of TNFSF13 (APRIL) in the South African Clawed Frog (Xenopus laevi): A New Model to Study Immunological Diseases." OMICS: A Journal of Integrative Biology 17, no. 7 (2013): 384–92. http://dx.doi.org/10.1089/omi.2013.0004.

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de Koning, Harry P., Bruce G. Jenks, Wim J. J. M. Scheenen, Eveline P. C. T. de Rijk, Raymond T. J. M. Caris та Eric W. Roubos. "Indirect Action of Elevated Potassium and Neuropeptide Y on αMSH Secretion from the Pars Intermedia of Xenopus laevis: A Biochemical and Morphological Study". Neuroendocrinology 54, № 1 (1991): 68–76. http://dx.doi.org/10.1159/000125853.

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Dores, Robert M., Tami C. Steveson, and Kristin Lopez. "Differential Mechanisms for the N-Acetylation of Alpha-Melanocyte-Stimulating Hormone and Beta-Endorphin in the Intermediate Pituitary of the Frog, Xenopus laevis." Neuroendocrinology 53, no. 1 (1991): 54–62. http://dx.doi.org/10.1159/000125697.

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Saveliev, S. V., N. V. Besova, E. S. Savelieva, and V. I. Gulimova. "NEUROBLASTS MIGRATION AND PATTERN FORMATION DURING DEVELOPMENT OF THE XENOPUS LAEVIS." CLINICAL AND EXPERIMENTAL MORPHOLOGY 29, no. 1 (2019): 63–70. http://dx.doi.org/10.31088/2226-5988-2019-29-1-63-70.

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Sive, H. L., R. M. Grainger, and R. M. Harland. "Xenopus laevis Einstecks." Cold Spring Harbor Protocols 2007, no. 12 (2007): pdb.prot4750. http://dx.doi.org/10.1101/pdb.prot4750.

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Parain, Karine, Sophie Lourdel, Alicia Donval, et al. "CRISPR/Cas9-Mediated Models of Retinitis Pigmentosa Reveal Differential Proliferative Response of Müller Cells between Xenopus laevis and Xenopus tropicalis." Cells 11, no. 5 (2022): 807. http://dx.doi.org/10.3390/cells11050807.

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Retinitis pigmentosa is an inherited retinal dystrophy that ultimately leads to blindness due to the progressive degeneration of rod photoreceptors and the subsequent non-cell autonomous death of cones. Rhodopsin is the most frequently mutated gene in this disease. We here developed rhodopsin gene editing-based models of retinitis pigmentosa in two Xenopus species, Xenopus laevis and Xenopus tropicalis, by using CRISPR/Cas9 technology. In both of them, loss of rhodopsin function results in massive rod cell degeneration characterized by progressive shortening of outer segments and occasional cell death. This is followed by cone morphology deterioration. Despite these apparently similar degenerative environments, we found that Müller glial cells behave differently in Xenopus laevis and Xenopus tropicalis. While a significant proportion of Müller cells re-enter into the cell cycle in Xenopus laevis, their proliferation remains extremely limited in Xenopus tropicalis. This work thus reveals divergent responses to retinal injury in closely related species. These models should help in the future to deepen our understanding of the mechanisms that have shaped regeneration during evolution, with tremendous differences across vertebrates.

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Arystarhova, E. "Toxicological biotesting of waters of surface sources of water service and drinking water using larvas of Хenopus laevis". Visnyk agrarnoi nauky 96, № 2 (2018): 60–63. http://dx.doi.org/10.31073/agrovisnyk201802-10.

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Shrestha, Bindesh, Prabhakar Sripadi, Brent R. Reschke, et al. "Subcellular Metabolite and Lipid Analysis of Xenopus laevis Eggs by LAESI Mass Spectrometry." PLoS ONE 9, no. 12 (2014): e115173. http://dx.doi.org/10.1371/journal.pone.0115173.

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Shaidani, Nikko-Ideen, Sean McNamara, Marcin Wlizla, and Marko E. Horb. "Obtaining Xenopus laevis Embryos." Cold Spring Harbor Protocols 2021, no. 3 (2020): pdb.prot106211. http://dx.doi.org/10.1101/pdb.prot106211.

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Thèses sur le sujet "Xenopus laevi"

MANN, ANJALI. "UNDERSTANDING THE ROLE OF POLQ IN CHROMOSOMAL DNA REPLICATION UNDER STRESSFUL CONDITIONS." Doctoral thesis, Università degli Studi di Milano, 2022. http://hdl.handle.net/2434/909725.

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DNA polymerase-theta (Polq) is a class A family DNA polymerase comprising of a helicase-like domain on the N-terminus and a DNA polymerase domain on the C-terminus. Pol-theta overexpression in breast and ovarian cancer patients correlate with high tumor grade and poor response to chemotherapeutic drugs. Consistently, Pol-theta inhibition is synthetically lethal with inactivation of BRCA1/2 genes, which are often found mutated in these tumors. The ability of Pol-theta to sustain viability of BRCA1/2 defective cancer cells has been attributed to its role in alternative end-joining repair of double strand breaks (DSBs) resulting from collapsed replication forks. In addition to DSBs a major role in BRCA1/2 activity is the suppression of defects associated with faulty DNA replication. Indeed, the occurrence of extensive DNA replication defects ranging from single stranded DNA gap accumulation to nascent DNA degradation in the absence of BRCA1/2 and RAD51 has been previously demonstrated. However, the role of Pol-theta in counteracting defective DNA replication in the absence of functional BRCA1/2 and RAD51 is poorly understood. To address this question, we cloned and purified the full length and different domains of Xenopus laevis Pol-theta and generated antibody to study Pol-theta function in replicating Xenopus egg extracts. Our preliminary findings indicate that Pol-theta has replication dependent and independent functions. Significantly, although dispensable for normal chromosomal DNA replication, Pol-theta is strongly enriched at stalled forks upon replication stress conditions induced by aphidicolin. Using DNA electron microscopy, we discovered that Pol-theta overexpression suppresses ssDNA gaps at the replication fork and replication fork reversal triggered by aphidicolin-induced fork stalling. Therefore, our results suggest that Pol-theta not only repairs DSBs but also prevents the occurrence of potentially harmful DNA replication intermediates. We are currently investigating Pol-theta function in relation to replicative defects arising in the absence of BRCA1/2 and RAD51. Better understanding of Pol-theta function at stalled forks will help to target breast and ovarian cancers more effectively.

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Pan, Tien-Chien Burggren Warren W. "Metabolic, cardiac and ventilatory regulation in early larvae of the South African clawed frog, Xenopus laevis." [Denton, Tex.] : University of North Texas, 2009. http://digital.library.unt.edu/ark:/67531/metadc12175.

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Minshull, Jeremy Stephen. "Cynlins in Xenopus laevis." Thesis, University of Cambridge, 1988. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.293835.

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Pan, Tien-Chien. "Metabolic, cardiac and ventilatory regulation in early larvae of the South African clawed frog, Xenopus laevis." Thesis, University of North Texas, 2009. https://digital.library.unt.edu/ark:/67531/metadc12175/.

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Early development of O2 chemoreception and hypoxic responses under normoxic (150 mmHg) and chronically hypoxic (110 mmHg) conditions were investigated in Xenopus laevis from hatching to 3 weeks post fertilization. Development, growth, O2 consumption, ventilatory and cardiac performance, and branchial neuroepithelial cells (NEC) density and size were determined. At 3 days post fertilization (dpf), larvae started gill ventilation at a rate of 28 ± 4 beats/min and showed increased frequency to 60 ± 2 beats/min at a PO2 of 30 mmHg. Also at 3 dpf, NECs were identified in the gill filament buds using immunohistochemical methods. Lung ventilation began at 5 dpf and exhibited a 3-fold increase in frequency from normoxia to a PO2 of 30 mmHg. Hypoxic tachycardia developed at 5 dpf, causing an increase of 20 beats/min in heart rate, which led to a 2-fold increase in mass-specific cardiac output at a PO2 of 70 mmHg. At 10 dpf, gill ventilatory sensitivity to hypoxia increased, which was associated with the increase in NEC density, from 15 ± 1 to 29 ± 2 cells/mm of filament at 5 and 10 dpf, respectively. Unlike the elevated rate, cardiac and ventilatory volumes were independent of acute hypoxia. Despite increased cardioventilatory frequency, larvae experienced an average of 80% depression in during acute hypoxia. Chronic hypoxia (PO2 of 110 mmHg) decreased mass-specific cardiac performance before 10 dpf. In older larvae (10 to 21 dpf), chronic hypoxia decreased acute branchial and pulmonary hypoxic hyperventilation and increased NEC size. Collectively, these data suggest that larvae exhibit strong O2-driven acute hypoxic responses post-hatching, yet are still O2 conformers. All acute hypoxic responses developed before 5 dpf, and then the effects of chronic hypoxia started to show between 7 and 21 dpf. Thus, the early formation of acute hypoxic responses is susceptible to the environment and can be shaped by the ambient PO2.

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Tucker, Abigail Saffron. "Tail development in Xenopus laevis." Thesis, University of Oxford, 1995. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.297296.

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Costa, R. "Endoderm patterning in Xenopus laevis." Thesis, University of Cambridge, 2004. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.598012.

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The endoderm is the inner germ layer of the vertebrate embryo from which the respiratory and digestive systems are derived. These include organs such as the liver, pancreas, stomach, lungs and intestine. Recent research has helped our understanding of early vertebrate endoderm specification and terminal differentiation of specific endodermal lineages. However, very little is known about the molecular mechanisms that control endoderm patterning and morphogenesis during vertebrate development. As a way to identify genes involved in these elusive steps of development, I performed a differential hybridisation screen in a macroarray tailbud ventral foregut cDNA library coupled with <i>in situ</i> hybridisation analysis. My aim was to identify and characterise new regionally expressed endodermal genes in <i>Xenopus laevis</i>, a classical embryologic model organism. Here, I report the identification and characterisation of a dozen novel regionally expressed endoderm genes. At tailbud stages their expression patterns fall into three re-occurring domains; anterior ventral midgut endoderm, posterior endoderm and dorsal endoderm. In addition, regional expression of some of these genes is observable at gastrula stages, endoderm specification. These are the first early stable endodermal markers for different regions of the gastrula endoderm. This suggests that the earliest steps in endoderm patterning are concurrent with endoderm specification. Furthermore I describe the identification of a mesodermal transcription factor, which appears to be expressed in ‘early embryonic macrophages’ - and a poorly characterised embryonic cell population. I present an overview of endoderm development together with the results from my screen. Overall, these results reveal an unexpected degree of early endodermal patterning and assist our understanding of the link between early and late events of vertebrate endoderm development. In addition, this work provides us with new and very useful markers for endodermal patterning, and potentially some key developmental regulators of endodermal formation.

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Marklew, Sarah. "Retinoid receptors in Xenopus laevis." Thesis, University of Warwick, 1994. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.283494.

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Benites, da Costa Ricardo Manuel. "Endodermal patterning in Xenopus laevis." Thesis, University of Cambridge, 2004. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.616152.

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Smith, Darrin Paul. "Xenopus laevis octamer-binding proteins." Thesis, University of Warwick, 1990. http://wrap.warwick.ac.uk/108633/.

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The ubiquitous human octamer-binding transcription factor, Oct-1, is believed to regulate the expression of a number of ubiquitously expressed genes. These include genes which are expressed throughout the cell-cycle (eg. snRNA genes) and histone H2B genes, whose expression is tightly coupled to nuclear DNA synthesis at S-phase of the cell-cycle. I have isolated and completely sequenced two X. laevis homologues of Oct-1. The high degree of relatedness of the two homologues indicates that these are likely to be copies of the same gene, which arose during the theoretical genome duplication event in X. laevis evolution. X. laevis and human Oct-1 display strong evolutionary conservation (85% Identity over a stretch of 750 amino acids), which presumably means that X. laevis has a similar, if not identical function to human Oct-1. Homology between human and X. laevis does, however, break down shortly before the N terminal end, at a point where alternate splicing is known to occur in hunan Oct-1 (W. Herr, pers. comn.). The full length X. laevis cDNA clone which I have isolated may represent a novel alternately spliced form of Oct-1. Two octamer-binding proteins have been identified (in band shift assays) in X. laevis oocyte, embryo and tissue extract. Oct-1, and a second, previously unidentified octamer-binding protein which has been termed Oct-R, for octamer-related. Oct-1 does not bind to a degenerate octamer motif most often seen in X. laevis H2B promoters. Oct-R binds more strongly to this degenerate motif than the consensus motif, but only in the context of the H2B promoter, and does not bind either motif in another sequence context. This suggests that Oct-R may have a role in regulation of H2B transcription, although no direct evidence has been obtained. Since Oct-1 is believed to stimulate the S-phase specific induction of histone H2B gene transcription the possibility that Oct-1 binding activity is cell-cycle regulated is of interest. X. laevis Oct-1 (and Oct-R) binding activity does not appear to be cell-cycle regulated. Oct-1 and Oct-R are stored in the oocyte (partly in the cytoplasm), in an amount equivalent to at least 80 000 somatic cells. Histone protein and message are stored in the oocyte as part of the mechanism to provide enough histones to keep-up with the high rate of DNA synthesis in early Xenopus development. It is possible that histone gene transcription factors are stored for the same purpose. By mutation of the octamer motif in the promoter of X. laevis histone H2B gene promoter I have tentatively concluded that the octamer motif is required for the expression of a H2B gene (independently of DNA synthesis) in the oocyte. The H2B gene occurs in association with a H2A gene, as part of a divergently expressed gene pair. The octamer motif may be required for the expression of both H2B and H2A genes. The degenerate octamer motif contained in this H2B promoter does not bind efficiently to Oct-1 in vitro, but binds well to Oct-R, indirectly suggesting that Oct-R is required for the expression of the H2B gene. A polyclonal antiserum raised against the N terminal domain of X. laevis Oct-1 reacts to proteins other than Oct-1 on Western blots of oocyte and embryo extract. These proteins, which are antigenically related to the N terminal domain of Oct-1, are entirely located in the cytoplasm of the oocyte, and entirely located in the nucleus of somatic cells. These proteins are synthesised during oogenesis, and stored in the oocyte in an amount equivalent to at least 100 000 somatic cells.

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Cleaver, Ondine Beatrice. "Neovascularization of the Xenopus embryo /." Digital version accessible at:, 1998. http://wwwlib.umi.com/cr/utexas/main.

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Livres sur le sujet "Xenopus laevi"

Smith, Darrin P. "Xenopus laevis" octamer-binding proteins. typescript, 1990.

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Marklew, Sarah. Retinoid receptors in xenopus laevis. typescript, 1994.

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Wiechmann, Allan F., and Celeste R. Wirsig-Wiechmann. Color Atlas of Xenopus laevis Histology. Springer US, 2003. http://dx.doi.org/10.1007/978-1-4419-9286-4.

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Lametschwandtner, Alois, and Bernd Minnich. Color Atlas of Adult Xenopus laevis. Springer International Publishing, 2022. http://dx.doi.org/10.1007/978-3-031-05110-4.

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Wiechmann, Allan F. Color atlas of Xenopus laevis histology. Kluwer Academic Publishers, 2003.

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Chong, James Paul Jonathon. Control of DNA replication in Xenopus laevis. University of Manchester, 1996.

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D, Nieuwkoop Pieter, and Faber Jacob 1926-, eds. Normal table of Xenopus laevis (Daudin): A systematical and chronological survey of the development from the fertilized egg till the end of metamorphosis. Garland Pub., 1994.

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Sive, Hazel L. Early development of Xenopus laevis: A laboratory manual. Cold Spring Harbor Laboratory Press, 2000.

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Peter, Hausen. The early development of Xenopus laevis: An atlas of the histology. Verlag der Zeitschrift für Naturforschung, 1991.

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Mason, Clive S. Transcriptional effects of retinoic acid in Xenopus laevis embryos. typescript, 1995.

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Chapitres de livres sur le sujet "Xenopus laevi"

Muñoz, William A., Amy K. Sater, and Pierre D. McCrea. "Development of Neural Tissues inXenopus laevis." In Xenopus Development. John Wiley & Sons, Inc, 2014. http://dx.doi.org/10.1002/9781118492833.ch13.

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Deshler, James O. "RNA Localization during Oogenesis inXenopus laevis." In Xenopus Development. John Wiley & Sons, Inc, 2014. http://dx.doi.org/10.1002/9781118492833.ch2.

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Rasar, Melissa A., and Stephen R. Hammes. "The Physiology of the Xenopus laevis Ovary." In Xenopus Protocols. Humana Press, 2006. http://dx.doi.org/10.1007/978-1-59745-000-3_2.

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Bröer, Stefan. "Xenopus laevis Oocytes." In Methods in Molecular Biology. Humana Press, 2010. http://dx.doi.org/10.1007/978-1-60761-700-6_16.

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Gradl, Dietmar. "Xenopus laevis (Südafrikanischer Krallenfrosch)." In Modellorganismen. Springer Berlin Heidelberg, 2019. http://dx.doi.org/10.1007/978-3-662-54868-4_7.

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Pomerening, Joseph R. "Xenopus laevis Egg Extract." In Encyclopedia of Systems Biology. Springer New York, 2013. http://dx.doi.org/10.1007/978-1-4419-9863-7_1331.

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Peters, Reiner. "Use of Xenopus laevis Oocyte Nuclei and Nuclear Envelopes in Nucleocytoplasmic Transport Studies." In Xenopus Protocols. Humana Press, 2006. http://dx.doi.org/10.1007/978-1-59745-000-3_18.

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Sims, Christopher E., Veronica Luzzi, and Nancy L. Allbritton. "Localized Sampling, Electrophoresis, and Biosensor Analysis of Xenopus laevis Cytoplasm for Subcellular Biochemical Assays." In Xenopus Protocols. Humana Press, 2006. http://dx.doi.org/10.1007/978-1-59745-000-3_29.

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Lametschwandtner, Alois, and Bernd Minnich. "Materials and Methods." In Color Atlas of Adult Xenopus laevis. Springer International Publishing, 2022. http://dx.doi.org/10.1007/978-3-031-05110-4_2.

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Lametschwandtner, Alois, and Bernd Minnich. "Microvasculature of Xenopus Tissues and Organs." In Color Atlas of Adult Xenopus laevis. Springer International Publishing, 2022. http://dx.doi.org/10.1007/978-3-031-05110-4_3.

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Actes de conférences sur le sujet "Xenopus laevi"

Fogliano, Chiara, Bice Avallone, Chiara Maria Motta, and Rosa Carotenuto. "Influence of Benzodiazepine Delorazepam on Xenopus laevis Embryogenesis." In The 7th World Congress on Civil, Structural, and Environmental Engineering. Avestia Publishing, 2022. http://dx.doi.org/10.11159/iceptp22.194.

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Serlin, Zachary, Jason Rife, and Michael Levin. "A Level Set Approach to Simulating Xenopus laevis Tail Regeneration." In Proceedings of the Artificial Life Conference 2016. MIT Press, 2016. http://dx.doi.org/10.7551/978-0-262-33936-0-ch085.

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POLLET, N., H. A. SCHMIDT, V. GAWANTKA, C. NIEHRS, and M. VINGRON. "IN SILICO ANALYSIS OF GENE EXPRESSION PATTERNS DURING EARLY DEVELOPMENT OF XENOPUS LAEVIS." In Proceedings of the Pacific Symposium. WORLD SCIENTIFIC, 1999. http://dx.doi.org/10.1142/9789814447331_0042.

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Troiani, Francesca, Konstantin Nikolic, and Timothy G. Constandinou. "Optical coherence tomography for detection of compound action potential in Xenopus Laevis sciatic nerve." In SPIE BiOS, edited by Steen J. Madsen, Victor X. D. Yang, E. Duco Jansen, Qingming Luo, Samarendra K. Mohanty, and Nitish V. Thakor. SPIE, 2016. http://dx.doi.org/10.1117/12.2209335.

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Yang, Hyunmo, Sanzhar Askaruly, Seongmin Yun, Geoseong Na, Taejoon Kwon, and Woonggyu Jung. "High-throughput screening platform for quantitative phenotype analysis of Xenopus laevis with deep learning." In SPIE Advanced Biophotonics Conference (SPIE ABC 2021), edited by Chulmin Joo, Hongki Yoo, Euiheon Chung, et al. SPIE, 2022. http://dx.doi.org/10.1117/12.2624884.

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Boppart, Stephen A., Gary J. Tearney, Brett E. Bouma, James G. Fujimoto, and Mark E. Brezinski. "Optical Coherence Tomography of Embryonic Morphology During Cellular Differentiation." In Advances in Optical Imaging and Photon Migration. Optica Publishing Group, 1996. http://dx.doi.org/10.1364/aoipm.1996.cit231.

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Improved imaging of morphological changes has the potential of offering new insight into the complex process of embryonic development. Optical coherence tomography (OCT), is a new imaging technique for performing in vivo cross-sectional imaging of architectural morphology by measuring backscattered infrared light. This study investigates the application of OCT for imaging developing structure in Xenopus laevis (African frog) and Brachydanio rerio (zebra fish), two developmental biology animal models. Images are compared to corresponding histological preparations. Cross sectional imaging can be performed and structural morphology identified at greater imaging depths than possible with confocal and light microscopy. Repeated OCT imaging may be performed in vivo in order to track structural changes throughout development. Imaging in vivo microscopic embryonic morphology with OCT is a fundamental biological research application for the study of genetic disease.

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Longo, D., S. Peirce, T. Skalak, et al. "Computational automata simulation of blastocoel roof thinning in the Xenopu laevis embryo." In Proceedings of the 2003 IEEE Systems and Information Engineering Design Symposium. IEEE, 2003. http://dx.doi.org/10.1109/sieds.2003.158015.

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Martus, Kevin, and Jashri Menon. "Charaterization Of A Plasma Source Used To Accelerate Wound Healing Of The Tadpole Xenopus Laevis*." In 2017 IEEE International Conference on Plasma Science (ICOPS). IEEE, 2017. http://dx.doi.org/10.1109/plasma.2017.8496133.

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Kim, YongTae, Sagar D. Joshi, Philip R. LeDuc, Lance A. Davidson, and William C. Messner. "Probing Multicellular Dynamics in Xenopus Laevis Embryonic Development Using a Mechanical Engineering Based Microfluidic Feedback Approach." In ASME 2010 Summer Bioengineering Conference. American Society of Mechanical Engineers, 2010. http://dx.doi.org/10.1115/sbc2010-19319.

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Spatial and temporal regulation of chemical environments in and around cells or tissues for long time periods is important to understand multicellular signaling since the responses to chemical factors control the resulting coordinated events in development. Although progress has been made in command of single cell environments, both long-term and high-speed control of multicellular chemical environments in development is still challenging. We have developed a mechanical engineering based microfluidic feedback approach that allows long-term and high-speed manipulation of a laminar flow interface in a microfluidic channel. This approach enabled long-term spatiotemporal control of chemical conditions over Animal Cap (AC) explants during the gastrulation stage in Xenopus laevis embryonic development. We present the responses of the explants to periodic stimulation of steroid hormone dexamethasone (DEX) by tracking a hormone-activated nuclear-localizing green fluorescent protein tagged glucocorticoid receptor (nuc-GR-GFP). We believe that our approach will be useful in diverse areas including dynamic system and control in microfluidics, embryonic development, and spatiotemporally integrated biological responses.

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Chanda, Diptiman, Anandi Sawant, Jonathan Adam Hensel, et al. "Abstract 5173: The human homologue of frog (Xenopus laevis) anterior gradient protein promotes metastasis via regulation of cellular adhesion." In Proceedings: AACR 103rd Annual Meeting 2012‐‐ Mar 31‐Apr 4, 2012; Chicago, IL. American Association for Cancer Research, 2012. http://dx.doi.org/10.1158/1538-7445.am2012-5173.

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Rapports d'organisations sur le sujet "Xenopus laevi"

Cline, Hollis T. Developing Xenopus Laevis as a Model to Screen Drugs for Fragile X Syndrome. Defense Technical Information Center, 2014. http://dx.doi.org/10.21236/ada608963.

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Cline, Hollis T. Developing Xenopus Laevis as a Model to Screen Drugs for Fragile X Syndrome. Defense Technical Information Center, 2013. http://dx.doi.org/10.21236/ada598718.

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Hensey, Carmel E. Cloning and Biochemical Analysis of the Ataxia-Telangiectasia (A-T) Gene in Xenopus Laevis. Defense Technical Information Center, 1999. http://dx.doi.org/10.21236/ada391306.

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