Articles de revues : « Vcadg »

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Lin, Wei Min, Hitoshi Ohmori, T. Suzuki, Yoshihiro Uehara, Y. Watanabe et Shinya MORITA. « Characteristics of Free Form Finishing Applying V-CAM System ». Key Engineering Materials 329 (janvier 2007) : 273–78. http://dx.doi.org/10.4028/www.scientific.net/kem.329.273.

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A new CAD system, which is called Volume-CAD (VCAD) have been developed. We carried out research and development of VCAD fabrication process based on VCAD/CAM precision control. In this study, a developed V-CAM had been used for a polishing fundamental experiment of a free form surface. The relationship between NC resolution and form accuracy of polished surface are discussed.

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Bramstedt, Katrina A. « Increasing Donation Opportunities for Vascularized Composite Allografts ». Progress in Transplantation 26, n^o 4 (20 août 2016) : 372–77. http://dx.doi.org/10.1177/1526924816664080.

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There are 40 vascularized composite allotransplant programs across 5 continents served by 31 organ procurement organizations (or equivalent). The organizations’ websites inform about organ and tissue donation. This research explored worldwide educational efforts on vascularized composite allograft (VCAG) donation via their corporate websites as well as options within donor registries and donor card systems to indicate a VCAG donation preference. Of these, 13 (41.9%) of 31 had VCAG content and 7 (22.6%) of 31 offered a mechanism for individuals to voice a preference about VCAG donation through an opt in donor registry or card or an opt out registry. In North America, the only donor registration/card system that facilitated VCAG donation is in Mexico. The resistance to consent for VACG donation is likely due to poor public education and the personal nature of face, hand, uterus, and penile allografts. Efforts to reduce this resistance can begin with the assistance of website content, registries, and donor cards.

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Ross, Bryan A., Andrew R. Brotto, Desi P. Fuhr, Devin B. Phillips, Sean van Diepen, Tracey L. Bryan et Michael K. Stickland. « The supine position improves but does not normalize the blunted pulmonary capillary blood volume response to exercise in mild COPD ». Journal of Applied Physiology 128, n^o 4 (1 avril 2020) : 925–33. http://dx.doi.org/10.1152/japplphysiol.00890.2019.

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Patients with mild chronic obstructive pulmonary disease (COPD) demonstrate resting pulmonary vascular dysfunction as well as a blunted pulmonary diffusing capacity (DLCO) and pulmonary capillary blood volume (VC) response to exercise. The transition from the upright to supine position increases central blood volume and perfusion pressure, which may overcome microvascular dysfunction in an otherwise intact alveolar-capillary interface. The present study examined whether the supine position normalized DLCO and VC responses to exercise in mild COPD. Sixteen mild COPD participants and 13 age-, gender-, and height-matched controls completed DLCO maneuvers at rest and during exercise in the upright and supine position. The multiple [Formula: see text]-DLCO method was used to determine DLCO, VC, and membrane diffusion capacity (DM). All three variables were adjusted for alveolar volume (DLCOAdj, VCAdj, and DMAdj). The supine position reduced alveolar volume similarly in both groups, but oxygen consumption and cardiac output were unaffected. DLCOAdj, DMAdj, and VCAdj were all lower in COPD. These same variables all increased with upright and supine exercise in both groups. DLCOAdj was unaffected by the supine position. VCAdj increased in the supine position similarly in both groups. DMAdj was reduced in the supine position in both groups. While the supine position increased exercise VCAdj in COPD, the increase was of similar magnitude to healthy controls; therefore, exercise VC remained blunted in COPD. The persistent reduction in exercise DLCO and VC when supine suggests that pulmonary vascular destruction is a contributing factor to the blunted DLCO and VC response to exercise in mild COPD. NEW & NOTEWORTHY Patients with mild chronic obstructive pulmonary disease demonstrate a combination of reversible pulmonary microvascular dysfunction and irreversible pulmonary microvascular destruction.

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Pasha, Tayyab, Rafaqat Ahmed, Muhammad Amir, Amir Iqbal et Ayesha Siddiqa. « EARLY OUTCOMES ». Professional Medical Journal 23, n^o 05 (10 mai 2016) : 583–88. http://dx.doi.org/10.29309/tpmj/2016.23.05.1588.

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Objectives: Off pump TACR/MACR performed in experienced hands hascomparable results to on pump TACR/MACR. Period: January-2012 to December-2015.Material and method: 405 patients with two and three vessel coronary artery disease (two &three VCAD) underwent OPCAB at the department of cardiac surgery, Jinnah hospital, Lahore.73 of them got total or multiple arterial coronary revascularizations. 34 patients (41%) hadtwo VCAD and 47 (59%) had three VCAD. Total arterial revascularization was performed in 70(95.8%) patients using right internal mammary artery and left internal mammary artery and/orradial artery. 3 (4.10%) patients got multiple arterial grafts using BITA, RA and SVG. Results:There was no death reported in first 30 days post operatively. Deep sternal wound infectionoccurred in only one patient. The rate of perioperative stroke and renal failure was zero. Two(2.46%) patients had acute MI and 1 patient was reopened due to bleeding. Conclusion: Weconclude that early outcome of OPCAB total or multiple arterial coronary revascularizations, inexperienced hands, are as safe and effective as ONCAB.

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MASUDA, Takatoshi, et Toshio NAGASHIMA. « 165 Nonlinear stress analysis using VCAD Framework ». Proceedings of The Computational Mechanics Conference 2006.19 (2006) : 583–84. http://dx.doi.org/10.1299/jsmecmd.2006.19.583.

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YOKOTA, Hideo. « S203 Development of VCAD Tools for Biomedical Simulation ». Proceedings of the Bioengineering Conference Annual Meeting of BED/JSME 2008.21 (2009) : 341–42. http://dx.doi.org/10.1299/jsmebio.2008.21.341.

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Imai, N., T. Nagashima et K. Kase. « Crack propagation simulator V-X3D based on VCAD framework ». IOP Conference Series : Materials Science and Engineering 10 (1 juin 2010) : 012053. http://dx.doi.org/10.1088/1757-899x/10/1/012053.

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NISHIMURA, Masaomi, Tetsuro MURAI, Masakatsu TSUNEKI, Yutaka OTAKE, Hideo YOKOTA, Kiwamu KASE, Ryutaro HIMENO et Akitake MAKINOUTI. « 523 Design of tailor made implants using VCAD system ». Proceedings of the JSME annual meeting 2006.5 (2006) : 101–2. http://dx.doi.org/10.1299/jsmemecjo.2006.5.0_101.

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Ohura, K., Z. Sun, Akitake Makinouchi et Cristian Teodosiu. « Volume-CAD : An Integrated Environment for Virtual Manufacturing and Structural Analysis ». Advanced Materials Research 23 (octobre 2007) : 17–24. http://dx.doi.org/10.4028/www.scientific.net/amr.23.17.

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The Volume-CAD System Research Program aims at developing a core technology for data integration of computerized design, analysis, manufacturing, and testing processes. The potential applications of the Volume-CAD environment cover a large area of engineering and biomedical design. In this paper, we shall mainly focus on the VCAD-based software for the structural analysis and the simulation of casting processes.

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Sun, Haoyue, Zhicheng Yu et Bining Zhang. « Research on short-term power load forecasting based on VMD and GRU ». PLOS ONE 19, n^o 7 (11 juillet 2024) : e0306566. http://dx.doi.org/10.1371/journal.pone.0306566.

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The traditional method for power load forecasting is susceptible to various factors, including holidays, seasonal variations, weather conditions, and more. These factors make it challenging to ensure the accuracy of forecasting results. Additionally, there is a limitation in extracting meaningful physical signs from power data, which ultimately reduces prediction accuracy. This paper aims to address these issues by introducing a novel approach called VCAG (Variable Mode Decomposition—Convolutional Neural Network—Attention Mechanism—Gated Recurrent Unit) for combined power load forecasting. In this approach, we integrate Variable Mode Decomposition (VMD) with Convolutional Neural Network (CNN). VMD is employed to decompose power load data, extracting valuable time-frequency features from each component. These features then serve as input for the CNN. Subsequently, an attention mechanism is applied to give importance to specific features generated by the CNN, enhancing the weight of crucial information. Finally, the weighted features are fed into a Gated Recurrent Unit (GRU) network for time series modeling, ultimately yielding accurate load forecasting results.To validate the effectiveness of our proposed model, we conducted experiments using two publicly available datasets. The results of these experiments demonstrate that our VCAG method achieves high accuracy and stability in power load forecasting, effectively overcoming the limitations associated with traditional forecasting techniques. As a result, this approach holds significant promise for broad applications in the field of power load forecasting.

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Simoni, Laura, Alessandra Scarton, Claudio Macchi, Federico Gori, Guido Pasquini et Silvia Pogliaghi. « Quantitative and Qualitative Running Gait Analysis through an Innovative Video-Based Approach ». Sensors 21, n^o 9 (23 avril 2021) : 2977. http://dx.doi.org/10.3390/s21092977.

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Quantitative and qualitative running gait analysis allows the early identification and the longitudinal monitoring of gait abnormalities linked to running-related injuries. A promising calibration- and marker-less video sensor-based technology (i.e., Graal), recently validated for walking gait, may also offer a time- and cost-efficient alternative to the gold-standard methods for running. This study aim was to ascertain the validity of an improved version of Graal for quantitative and qualitative analysis of running. In 33 healthy recreational runners (mean age 41 years), treadmill running at self-selected submaximal speed was simultaneously evaluated by a validated photosensor system (i.e., Optogait—the reference methodology) and by the video analysis of a posterior 30-fps video of the runner through the optimized version of Graal. Graal is video analysis software that provides a spectral analysis of the brightness over time for each pixel of the video, in order to identify its frequency contents. The two main frequencies of variation of the pixel’s brightness (i.e., F1 and F2) correspond to the two most important frequencies of gait (i.e., stride frequency and cadence). The Optogait system recorded step length, cadence, and its variability (vCAD, a traditional index of gait quality). Graal provided a direct measurement of F2 (reflecting cadence), an indirect measure of step length, and two indexes of global gait quality (harmony and synchrony index). The correspondence between quantitative indexes (Cadence vs. F2 and step length vs. Graal step length) was tested via paired t-test, correlations, and Bland–Altman plots. The relationship between qualitative indexes (vCAD vs. Harmony and Synchrony Index) was investigated by correlation analysis. Cadence and step length were, respectively, not significantly different from and highly correlated with F2 (1.41 Hz ± 0.09 Hz vs. 1.42 Hz ± 0.08 Hz, p = 0.25, r2 = 0.81) and Graal step length (104.70 cm ± 013.27 cm vs. 107.56 cm ± 13.67 cm, p = 0.55, r2 = 0.98). Bland–Altman tests confirmed a non-significant bias and small imprecision between methods for both parameters. The vCAD was 1.84% ± 0.66%, and it was significantly correlated with neither the Harmony nor the Synchrony Index (0.21 ± 0.03, p = 0.92, r2 = 0.00038; 0.21 ± 0.96, p = 0.87, r2 = 0.00122). These findings confirm the validity of the optimized version of Graal for the measurement of quantitative indexes of gait. Hence, Graal constitutes an extremely time- and cost-efficient tool suitable for quantitative analysis of running. However, its validity for qualitative running gait analysis remains inconclusive and will require further evaluation in a wider range of absolute and relative running intensities in different individuals.

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Michikawa, Takashi, Kiwamu Kase, Yutaka Ohtake, Zhigang Sun, Cristian Teodosiu et Akitake Makinouchi. « 3113 Hexahedral Mesh Generation by VCAD and Dual Meshes for Structural Analysis ». Proceedings of Design & ; Systems Conference 2006.16 (2006) : 282–83. http://dx.doi.org/10.1299/jsmedsd.2006.16.282.

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MAKINOUCHI, Akitake. « S201 VCAD system : a base for integrating modeling and simulation of multiple processes ». Proceedings of the Bioengineering Conference Annual Meeting of BED/JSME 2008.21 (2009) : 337–38. http://dx.doi.org/10.1299/jsmebio.2008.21.337.

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IMAI, Noboru, Toshio NAGASHIMA et Kiwamu KASE. « 1306 Implementation of crack propagation simulation to VCAD based analysis software V-X3D ». Proceedings of The Computational Mechanics Conference 2009.22 (2009) : 364–65. http://dx.doi.org/10.1299/jsmecmd.2009.22.364.

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MAKINOUCHI, Akitake. « W03(1) Integration of modeling and simulation processes based on VCAD system environment ». Reference Collection of Annual Meeting 2006.8 (2006) : 273–74. http://dx.doi.org/10.1299/jsmemecjsm.2006.8.0_273.

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Itani, Norihiko, Y. Watanabe, W. Lin, Y. Uehara, Shinya MORITA, T. Mishima, Hitoshi Ohmori et Akitake Makinouchi. « R&D of Ray Tracing Simulation Software and Fabrication Technologies Based on VCAD (Volume-CAD) Concept for GRIN Lens ». Key Engineering Materials 381-382 (juin 2008) : 109–12. http://dx.doi.org/10.4028/www.scientific.net/kem.381-382.109.

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We have been developing an intellectual manufacturing process applying IT (V-Cam system fabrication processes) based on Volume-CAD (VCAD) system which can express internal information of materials. This paper introduces the ultra-precision grinding, ray tracing (optical path) simulation software ‘V-Opt’ and the measurement of actual optical functions in the development of optical element taking gradient refractive index (GRIN) lens with functionally graded material properties as a model. In finish ground GRIN lens using SD#8000 wheel, the P-V (Peek to Value) of 27.07 nm, surface roughness (Ra) of 1.83 nm is obtained. ‘V-Opt’ developed for GRIN lens have two main functions; one is the visualizations of ray tracing and the other is the evaluation of spot diagram and focal length.

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KASE, Kiwamu, Takashi KANAI et Yutaka OHTAKE. « WS4-3 The outline of Volume-CAD and implicit surfaces on VCAD modeling(2) ». Proceedings of the Fluids engineering conference 2006 (2006) : _WS4–3–1_—_WS4–3–4_. http://dx.doi.org/10.1299/jsmefed.2006._ws4-3-1_.

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KASE, Kiwamu, Takashi KANAI et Yutaka OHTAKE. « WS4-3 The outline of Volume-CAD and implicit surfaces on VCAD modeling(1) ». Proceedings of the Fluids engineering conference 2006 (2006) : _WS4–3—a_. http://dx.doi.org/10.1299/jsmefed.2006._ws4-3-a_.

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Ohmori, H., Y. Uehara, W. Lin, Y. Watanabe, K. Katahira, T. Naruse, N. Mitsuishi et S. Ishikawa. « New ELID Grinding Technique for Desk-top Grinding System Based on VCAD Concept(Nanoprecision Elid-grinding (continued)) ». Proceedings of International Conference on Leading Edge Manufacturing in 21st century : LEM21 2005.2 (2005) : 703–8. http://dx.doi.org/10.1299/jsmelem.2005.2.703.

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Fukasaku, K., M. Negoro, H. Iwase, K. Yokoi et R. Himeno. « Computational Fluid Dynamics for Brain Circulation and Aneurysm with Therapeutic Devices ». Interventional Neuroradiology 10, n^o 2_suppl (décembre 2004) : 108–12. http://dx.doi.org/10.1177/15910199040100s220.

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We analysed fluid dynamics at brain arteries having multiple inflow and out flow like Willis ring based on clinical imaging modalities. In addition, we analysed fluid dynamics with therapeutic devices like coils and stents to simulate their influences to blood flow. 3D CTA and MRA obtained three-dimensional structures of the brain vessels. The centreline was obtained from the three dimensional structure. Diameter of the blood vessels was measured by 3D CTA/MRA then smooth surfaced blood vessel models were created. For the fluid analysis, we developed a home brew software which can display parameters such as streamline, etc. In addition, our CFD (computational fluid dynamics) software can work in collaboration with a CAD (computer aided design) software which we also developed (VCAD: Volume CAD). So, therapeutic devices such as coils, balloons and stents could be placed in the models and CFD analysis could be performed placing devices in the models. The flow pattern in the complicated vascular structure could be calculated such as Willis ring which has multiple inputs like ICA, VA and multiple outlets like MCA and PCA with communicating arteries. CFD with therapeutic devices could also analysed with our system.

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Watanabe, Yutaka, Hitoshi Ohmori, Weimin Lin, Yoshihiro Uehara, Toru Suzuki, Shin-ya Morita, Nobuhide Mitsuishi et Akitake Makinouchi. « Development of Aspherical Gradient Index (GRIN) Lens Fabrication System based on VCAD Concept and ELID Grinding(Nanoprecision Elid-grinding (continued)) ». Proceedings of International Conference on Leading Edge Manufacturing in 21st century : LEM21 2005.2 (2005) : 697–702. http://dx.doi.org/10.1299/jsmelem.2005.2.697.

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Usman, Hafiz Tahir, Kashif Ali Hashmi, Mohammad Sohail Saleemi et Ammar Akhtar. « ASSOCIATION OF ST ELEVATION IN LEAD AVR WITH LEFT MAIN STEM AND TRIPLE VESSEL DISEASES IN PATIENTS WITH NON-ST ELEVATION MYOCARDIAL INFARCTION ». Pakistan Heart Journal 54, n^o 4 (8 janvier 2022) : 348–51. http://dx.doi.org/10.47144/phj.v54i4.2128.

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Objectives: To determine frequency of left main stem (LMS) and triple vessel coronary artery disease (3VCAD) in patients of Non-ST-elevation myocardial infarction (NSTEMI) and to compare the frequency of LMS and 3VCAD in patients with NSTEMI with or without ST elevation in lead aVR. Methodology: Total 346 patients with NSTEMI having age 30-70 years were included in this descriptive cross-sectional study. The data on demographic details was collected. All patients underwent electrocardiography (ECG) and cardiac specific troponin-I assessment. Patients were categorized as NSTEMI with or without ST-elevation in lead aVR. Coronary angiography was performed in all patients and angiographic findings were noted. Results: Mean age of patients was 51.87±10.03 years. There were 218 (63.01%) males and 128 (36.99%) female patients. 182 (52.60%) patients of NSTEMI had ST elevation in aVR. LMS disease was found in 53 (29.10%) patients with ST elevation in aVR. Sensitivity, specificity, positive predive value and negative predictive value of ST elevation in aVR for LMS disease was 62.35%, 50.57%, 29.12% and 80.49% respectively. 3 VCAD was found in 54 (29.70%) with ST elevation in aVR. Sensitivity, specificity, positive predive value and negative predictive value of ST elevation in aVR for 3VCAD was 77.14%, 53.52%, 29.67% and 90.24% respectively. Conclusion: NSTEMI patients with ST elevation in aVR may have higher chances of having LMS disease or 3VCAD. There is high negative predictive value for ST elevation in aVR to predict LMS disease or 3VCAD.

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Shin, Sungho, Seongju Lee, Changhyun Jun et Kyoobin Lee. « BattleSound : A Game Sound Benchmark for the Sound-Specific Feedback Generation in a Battle Game ». Sensors 23, n^o 2 (10 janvier 2023) : 770. http://dx.doi.org/10.3390/s23020770.

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A haptic sensor coupled to a gamepad or headset is frequently used to enhance the sense of immersion for game players. However, providing haptic feedback for appropriate sound effects involves specialized audio engineering techniques to identify target sounds that vary according to the game. We propose a deep learning-based method for sound event detection (SED) to determine the optimal timing of haptic feedback in extremely noisy environments. To accomplish this, we introduce the BattleSound dataset, which contains a large volume of game sound recordings of game effects and other distracting sounds, including voice chats from a PlayerUnknown’s Battlegrounds (PUBG) game. Given the highly noisy and distracting nature of war-game environments, we set the annotation interval to 0.5 s, which is significantly shorter than the existing benchmarks for SED, to increase the likelihood that the annotated label contains sound from a single source. As a baseline, we adopt mobile-sized deep learning models to perform two tasks: weapon sound event detection (WSED) and voice chat activity detection (VCAD). The accuracy of the models trained on BattleSound was greater than 90% for both tasks; thus, BattleSound enables real-time game sound recognition in noisy environments via deep learning. In addition, we demonstrated that performance degraded significantly when the annotation interval was greater than 0.5 s, indicating that the BattleSound with short annotation intervals is advantageous for SED applications that demand real-time inferences.

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Karan, Radmila, Suzana Cvjeticanin, Natasa Kovacevic-Kostic, Dejan Nikolic, Milos Velinovic, Vladimir Milicevic et Biljana Obrenovic-Kircanski. « Genetic and Environmental Dispositions for Cardiovascular Variability : A Pilot Study ». Journal of Clinical Medicine 7, n^o 9 (23 août 2018) : 232. http://dx.doi.org/10.3390/jcm7090232.

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Background: The aim of our study was to evaluate the degree of genetic homozygosity in the group of patients with coronary artery disease (CAD), as well as to evaluate morphogenetic variability in CAD patients regarding the presence of investigated risk factors (RF) compared to a control sample of individuals. Additionally, we aimed to evaluate the distribution of ABO blood type frequencies between tested samples of individuals. Methods: This study analyzed individual phenotype and morphogenetic variability of 17 homozygously-recessive characteristics (HRC), by using HRC test in a sample of 148 individuals in CAD patients group and 156 individuals in the control group. The following RF were analyzed: hypertension, diabetes mellitus, hyperlipidemia, and smoking. Results: The mean value of HRC in CAD patients is significantly higher, while variability decreases compared to the control sample (CAD patients: 4.24 ± 1.59, control sample: 3.75 ± 1.69; VCAD-patients = 37.50%, VC = 45.07%). There is a significant difference in individual variations of 17 HRC between control sample and CAD patients (χ2 = 169.144; p < 0.01), which points out to different variability for tested genes. Mean values of HRC significantly differed in CAD patients in regard to the number of RF present. A blood type (OR = 1.75) is significant predictor for CAD, while O blood type (OR = 0.43) was significantly associated with controls. Conclusion: There is a higher degree of recessive homozygosity in CAD patients versus individuals in the control sample, and the presence of significant variations in the degree of recessive homozygosity as the number of tested RF increases.

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Rivier, Pierre-Adrien, Dorina Jamniczky, Attila Nemes, András Makó, Gyöngyi Barna, Nikolett Uzinger, Márk Rékási et Csilla Farkas. « Short-term effects of compost amendments to soil on soil structure, hydraulic properties, and water regime ». Journal of Hydrology and Hydromechanics 70, n^o 1 (12 février 2022) : 74–88. http://dx.doi.org/10.2478/johh-2022-0004.

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Abstract Despite the increasing interest in applying composts as soil amendments worldwide, there is a lack of knowledge on short-term effects of compost amendments on soil structural and hydraulic properties. Our goal was to study the effect of compost and vermicompost-based soil amendments on soil structure, soil water retention characteristics, aggregate stability and plant water use efficiency compared to that of mineral fertilizers and food-waste digestate and examine if these effects are evident within a short time after application. We set up a pot experiment with spring wheat using a sandy and a loamy soil receiving either mineral fertilizer (MF); dewatered digestate from anaerobic digestion of food waste (DG), vermicomposted digestate (VC_DG); sewage sludge-based compost (C_SS) and sewage sludge-based vermicompost (VC_SS). We then monitored and calculated the soil water balance components (irrigation, outflow, evaporation, transpiration, and soil water content). At harvest, we measured shoot biomass, soil texture, bulk density, water retention characteristics and aggregate stability. The irrigation use efficiency (IE) and the plant water use efficiency (WUE) were calculated for each treatment by dividing the transpiration and the dry shoot biomass with the amount of water used for irrigation, respectively. For the sandy soil, we used X-Ray computed tomography to visualise the pore system after applying organic amendments and to derive metrics of the pore-network such as its fractal dimension, imaged macroporosity and critical pore diameter. X-Ray tomography indicated that composting and vermicomposting resulted in more complex and diverse porous system and increased soil macroporosity. The increased fractal dimensions also indicated that compost and vermicompost can contribute to structure formation and stabilization within a short time after their application. Despite the small application rate and short incubation time, the application of organic amendments to the two different soil types resulted in improved soil water holding capacity and water use efficiency. Composting and vermicomposting appeared to have the best effect at reducing the irrigation demand and evaporation losses and increasing the water use efficiency of the plant, likely through their effect on soil structure and the pore-size distribution.

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Aponte-Daza, Vaneska Cindy, Freddy Ponce Valdivia, Bismarck Pinto Tapia et Felipe Garcia. « Duelo anticipado y afrontamiento al estrés en cuidadores informales de personas de la tercera edad ». LIBERABIT. Revista Peruana de Psicología 28, n^o 2 (31 décembre 2022) : e621. http://dx.doi.org/10.24265/liberabit.2022.v28n2.621.

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Antecedentes: el duelo anticipado es el proceso por el que pasan algunas personas antes del fallecimiento de un ser querido o de que se confirme su muerte. Ocurre cuando varias circunstancias hacen prever que tarde o temprano un ser querido, como un familiar, una pareja o un amigo, va a morir. Objetivo: el objetivo de estudio fue conocer cuáles son las estrategias de afrontamiento al estrés y factores personales del cuidado y del cuidador que benefician o ponen en riesgo el duelo anticipado en cuidadores informales de personas de la tercera edad. Método: participaron 272 cuidadores informales. Se utilizó la Escala del Duelo en el Cuidador de Meichsner et al. (2016) y la Escala Breve de Afrontamiento al Estrés (COPE 28) de Carver (1997). Resultados: los resultados evidencian que el duelo anticipado es influenciado por el afrontamiento: el dolor emocional por el afrontamiento basado en apoyo (OR = .236), afrontamiento evasión a la emoción (OR = 3.751) y estar todo el día de cuidado (OR = 3.061). La pérdida emocional es estimada por el afrontamiento focalizado en el problema (OR = .201), cuando el cuidador es un adulto mayor (OR = .303) y por el medio tiempo de cuidado (OR = 2.029). La aceptación de la pérdida es influenciada por el afrontamiento focalizado al problema (OR = .172), afrontamiento evasión a la emoción (OR = 4.409), cuidador es adulto joven (OR = 2.361) y por el cuidado durante casi todo el día (OR = .536). Además, la pérdida absoluta se asoció con el afrontamiento focalizado en el problema (r = .249) y el afrontamiento de evasión con sustancias (r = .216). Conclusiones: este estudio logra identificar factores personales y tipos de afrontamiento al estrés que favorecen o disminuyen el duelo anticipado en el cuidador primario informal. Particularmente, la probabilidad de presentar dolor emocional aumenta de acuerdo al afrontamiento basado en el apoyo o el espiritual, pero disminuye con el afrontamiento basado en la evasión emocional y la mayor convivencia con el enfermo. Contribución de autoría VCAD: revisión bibliográfica, elaboración de la introducción, de la justificación, del planteamiento del problema, del marco teórico, selección de la población, toma de pruebas, y elaboración de resultados y conclusiones. FPV: vaciado de datos, elaboración de base de datos, análisis de datos, creación de tablas, elaboración del método, elaboración de resultados y conclusiones. BPT: profesor guía. FG: revisión del artículo y sugerencias de correcciones.

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Lee, Elizabeth, Liqi Shu, Setareh Salehi Omran, Eric D. Goldstein, Thanh N. Nguyen, James E. Siegler, Farhan Khan, Christoph Stretz, Karen L. Furie et Shadi Yaghi. « Abstract TP173 : Differential Outcomes and Treatment in Vertebral versus Carotid Artery Dissections : A National Inpatient Sample Study ». Stroke 55, Suppl_1 (février 2024). http://dx.doi.org/10.1161/str.55.suppl_1.tp173.

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Introduction: Cervical artery dissection (CAD) involves the carotid (CCAD) or vertebral artery (VCAD). However, limited studies have compared their clinical features and outcomes. Our study utilized a comprehensive nationwide database to discern these differences. Method: We examined non-traumatic CAD-diagnosed patients from the U.S. National Inpatient Sample (2005-2019) using ICD-9 and ICD-10 codes. The evaluation included patient demographics, comorbidities, in-hospital complications, treatment, and costs. Differences between CCAD and VCAD were assessed using survey-weighted stepwise backward logistic regression, followed by propensity score matched adjusted regressions for outcomes. Result: From 2005 to 2019, we identified 157,086 CAD admissions, of which 79.9% (125,477) were spontaneous CADs, with CCAD outnumbering VCAD (67,671 vs. 57,806). Compared to VCAD, CCAD was significantly associated with older age (54 [44-66] vs. 49 [37-62]), Black race (12.6% vs. 8.7%), atrial fibrillation (6.1% vs. 3.7%), hypertension (58.0% vs. 53.9%), fewer concurrent acute ischemic strokes (AIS) (22.1% vs. 24.7%), higher NIHSS (mean NIHSS 7 [2-16] vs. 2 [0-5]), extended stays (4 days [2-8] vs. 4 days [2-7]) and increased hospitalization charges ($52,005 [$25,759-$118,806] vs. $43,199 [$24,116-$85,701]); all P<0.05. Within the concurrent AIS group, the CCAD group also exhibited an increased likelihood for IV thrombolysis (10.7% vs. 5.7%) and mechanical thrombectomy (14.9% vs. 3.7%). After propensity score matching for NIHSS and age, the CCAD group was associated with less death (adjusted odds ratio [aOR] 0.41, 95% CI 0.26-0.65, P<0.001) but a similar home discharge rate (aOR 1.15, 95% CI 0.78-1.69, P=0.480) (Figure). Conclusion: Our study underscores distinct comorbidity profiles and treatment patterns between CCAD and VCAD groups. These findings advocate for tailored treatment strategies based on dissection type to optimize patient outcomes.

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Muraru, Denisa, Marco Previtero, Roberto C. Ochoa-Jimenez, Andrada C. Guta, Stefano Figliozzi, Dario Gregori, Daniele Bottigliengo, Gianfranco Parati et Luigi P. Badano. « Prognostic validation of partition values for quantitative parameters to grade functional tricuspid regurgitation severity by conventional echocardiography ». European Heart Journal - Cardiovascular Imaging, 28 novembre 2020. http://dx.doi.org/10.1093/ehjci/jeaa282.

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Abstract Aims Quantitative echocardiography parameters are seldom used to grade tricuspid regurgitation (TR) severity due to relative paucity of validation studies and lack of prognostic data. To assess the relationship between TR severity and the composite endpoint of death and hospitalization for congestive heart failure (CHF); and to identify the threshold values of vena contracta width (VCavg), effective regurgitant orifice area (EROA), regurgitant volume (RegVol), and regurgitant fraction (RegFr) to define low, intermediate, and high-risk TR based on patients’ outcome data. Methods and results A cohort of 296 patients with at least mild TR underwent 2D, 3D, and Doppler echocardiography. We built statistical models (adjusted for age, NYHA class, left ventricular ejection fraction, and pulmonary artery systolic pressure) for VCavg, EROA, RegVol, and RegFr to study their relationships with the hazard of outcome. The tertiles of the derived hazard values defined the threshold values of the quantitative parameters for TR severity grading. During 47-month follow-up, 32 deaths and 72 CHF occurred. Event-free rate was 14%, 48%, and 93% in patients with severe, moderate, and mild TR, respectively. Severe TR was graded as VCavg > 6 mm, EROA > 0.30 cm2, RegVol > 30 mL, and RegF > 45%. Conclusion This outcome study demonstrates the prognostic value of quantitative parameters of TR severity and provides prognostically meaningful threshold values to grade TR severity in low, intermediate, and high risk.

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Jing, Zongxu, Changming Zhang, Xiangtao LI, Huan Zhang, Luyuan Niu, Yaping Feng, Yong Liu, Yunlong Yue, Xuemei Du et Xiaoyun Luo. « Cystic Adventitial Disease of the Popliteal Vein : A Case Report ». Vascular and Endovascular Surgery, 27 septembre 2022, 153857442211308. http://dx.doi.org/10.1177/15385744221130842.

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Venous cystic adventitial disease (VCAD) is a rare vascular anomaly located in the common femoral vein in most cases. We describe the case of a 59-year-old female patient with right leg edema who was misdiagnosed with deep vein thrombosis of the lower extremity at another hospital. Magnetic resonance angiography revealed a round mass in the popliteal vein, with a narrow lumen. Considering the location of the lesion, absence of a history of deep venous thrombosis and trauma, and clinical manifestations, the diagnosis is likely a popliteal vein adventitial cyst. Segmental popliteal vein resection and reconstruction were performed using a cylindrical great saphenous vein graft. No joint connection was found during the operation, and the postoperative pathology confirmed VCAD.

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Nguyen, Chau Thi Thu, Seung-Ok Yang et Won-Sil Choi. « Changes in sucrose and the VcADR gene induced sugar accumulation in blueberries during ripening and after chitosan treatment ». Journal of Berry Research, 2 juillet 2022, 1–14. http://dx.doi.org/10.3233/jbr-220016.

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BACKGROUND: The sweetness of highbush blueberries (Vaccinium corymbosum L.) is related to changes in sucrose and other primary sugar metabolites. OBJECTIVE: This study compared the fruit quality and sugar metabolism in the blueberry cultivars Brigitta and Elizabeth at three ripening stages and with a postharvest chitosan treatment to determine which factors are important in sugar metabolism in the two cultivars. METHODS: Blueberries were harvested at three ripening stages. Fully ripe fruit was treated with chitosan and kept at room temperature for 5 and 10 days. GC-MS was used to measure organic acids, individual sugars, and sugar derivatives. Gene expression was analysed using qPCR. RESULTS: Elizabeth fruit was less firm than Brigitta fruit, but contained more soluble solids. The sweeter taste of Elizabeth versus Brigitta was due to down-regulated VcINV, VcSPS, and VcADR transcription and increased sucrose concentration. Chitosan inhibited VcADR and VcINV transcription in Elizabeth, but activated these genes in Brigitta after 5 days of storage. CONCLUSIONS: Aldose reductase might be an essential enzyme in blueberry sugar metabolism. These findings support research on the mechanism of sugar accumulation in fruit during maturation and after postharvest treatments in blueberries.

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« 3D and 4D US for Congenital Defects ». Donald School Journal of Ultrasound in Obstetrics and Gynecology 4, n^o 4 (2010) : 349–60. http://dx.doi.org/10.5005/jp-journals-10009-1155.

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ABSTRACT Invent of 3D and 4D ultrasound has made a dramatic improvement in fetal imaging. Various viewing directions and rendering modes help better demonstration of pathologies suspected on 2D US. Multiplanar mode is the key of the 3D US imaging. Software like magicut and TUI help to understand the anatomy better. Volume ultrasound is an excellent tool for diagnosis of facial defects, spinal abnormalities, limb abnormalities, etc. 4D US shows fetal movements and expressions that are basis for the neurodevelopment of the fetus. STIC and VCAD are the tools that have made detection of fetal cardiac anomalies more precise.

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Ambroziak, M., J. Franke, A. Wojcicka, M. Kolanowska et A. Budaj. « SYNE1 gene novel variant is associated with myocardial infarction in young people with a family history of premature atherosclerosis ». European Heart Journal 44, Supplement_2 (novembre 2023). http://dx.doi.org/10.1093/eurheartj/ehad655.3263.

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Abstract Introduction Genetic background is thought to be responsible for a family occurred premature atherosclerosis, including myocardial infarction (MI). Purpose The aim of the study was to investigate the role of genetic variants in young patients (aged <50 years) with MI and family history of premature atherosclerosis. Methods The studied group consisted of 70 patients aged 26-49 (mean 43.1, SD ±4.3), 17 women and 53 men, with MI and with family history of premature atherosclerosis, defined as MI or ischaemic stroke in first-degree relatives at age <65 years in women or <55 years in men. The mean BMI in the studied group was 28.8 kg/m2 (SD ±3.5), total cholesterol level 202.3 mg/dl (SD ±3.5), HDL 40.6 mg/dl (SD ±9.6), LDL 124.0 mg/dl (SD ±28.9), triglycerides 164.4 mg/dl (SD ±63.5), glucose 108.3 mg/dl (SD ±19.9) and creatinine 0.9 mg/dl (SD ±0.2). Regarding other risk factors 63 patients (90%) were smokers (mean 24.1 pack-years, SD ±13.0), 44 (62.8%) had hypertension, 11 (15.7%) had diabetes mellitus, and 8 (11.4%) had depression. All patients had diagnosed MI including MI with ST elevation (STEMI) in 18 cases (25.7%) and MI without ST elevation (NSTEMI) in 52 cases (74.3%). All patients, except 2 (no consent), had performed coronary angiography revealing 1-vessel coronary artery disease (VCAD) in 33 patients (47.1%), 2-VCAD in 17 patients (24.3%), and 3-VCAD in 20 patients (28.6%). The mean left ventricular ejection fraction (LVEF) was 51.8% (SD ±8.0). The total DNA has been extracted from whole peripheral blood samples. The targeted enrichment library was prepared and analyzed using New Generation Sequencing method on Hiseq4000, 2x150 cycles. Statistical analyses were performed using the R software package (www.r-project.org/). The results of sequencing were compared to data from the reference control population consisting of 597 healthy people (418 women, 179 men) aged 18-83 (mean 40.5, SD ± 12,4) as a whole and after matching with a studied group by age and gender in a proportion 1:3 (210 people, 51 women and 159 men, aged 18-77, mean 42.1, SD ±10.6) using Propensity Score Matching. Risks associated with detected variants were evaluated using Fisher’s exact test based on the allelic frequencies of variants in both groups. Results SYNE1 gene variant rs36215567 (NM_182961.4: c.20396+22A>G) has been detected in statistically significant higher incidence in the studied group in comparison to the control population (p=0.005) with OR=4,80 (95%CI 1,43-14,45) as well as when compared to the control population matched by age and gender (p=0.004) OR=9,31 (95%CI 1,64-95,41). There were no statistically significant differences in the incidence of familial hypercholesterolemia related gene variants: LDLR c.667G>A, PCSK9 c.658-36G>A, PCSK9 c.996+55C>A and APOB c.12382G>A between both cohorts. Conclusion A novel variant of SYNE1 gene is associated with myocardial infarction in young age patients with a family history of premature atherosclerosis.

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Previtero, M., A. C. Guta, R. C. Ochoa-Jimenez, S. Figliozzi, C. Palermo, A. Baritussio, A. Cecchetto et al. « 38 Prognostic validation of partition values obtained with conventional two-dimensional and doppler echocardiography to grade tricuspid regurgitation severity ». European Heart Journal - Cardiovascular Imaging 21, Supplement_1 (1 janvier 2020). http://dx.doi.org/10.1093/ehjci/jez319.

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Abstract Background Morbidity and mortality associated with severe tricuspid regurgitation (TR) have prompted interest in new corrective transcatheter procedures. However, to properly select patients for interventional procedures, and to assess their effectiveness, a reliable and reproducible grading system of TR severity is mandatory. However, the cut-off values used by current guidelines to differentiate among mild, moderate and severe TR lack clinical validation. Purpose We aimed to obtain the threshold values of the currently recommended quantitative echocardiographic parameters used to grade TR severity using pts’ outcome as a reference. Methods 296 pts, with at least mild TR and complete 2D, 3D and Doppler echocardiographic study, were enrolled and assessed for potential confounders: age, NYHA class, left ventricular ejection fraction, coexistent valvular heart disease and right ventricular (RV) systolic pressure. Average diameter of the vena contracta (VCavg), effective regurgitant orifice area (EROA), regurgitant volume (RVol) and regurgitant fraction (RF) were obtained to grade TR severity. Median follow-up was 47 (17-80) months. The primary composite endpoint was the occurrence of death of any cause or hospitalization for right heart failure (RHF). Survival curves for the composite endpoint were divided in quartiles at median follow-up. Cut-off values for the echo parameters were derived to grade mild (below the 1st quartile), moderate (between 1st and 3rd quartiles), and severe (above the 3r quartile) TR. Results 33 deaths and 72 hospitalizations for RHF occurred. Event-free rate from death or RHF at the end of follow-up was 14%, 46% and 93% in pts with severe, moderate, and mild TR, respectively. Differences reached statistical significance early (at 1 month), and lasted during the whole follow-up period (Figure). The new threshold values for mild, moderate and severe TR are summarized in Table. Conclusions Partition values of quantitative echo-Doppler parameters used to grade mild, moderate and severe TR according to pts’ clinical outcome are significantly lower than those currently reported in guidelines. Further studies are needed to test if these new threshold values for severe TR will translate in earlier referral of pts to valve repair and improved prognosis. Mild Moderate Severe VCavg <3 mm 3-6 mm >6 mm EROA <0.15 cm² 0.15-0.30 cm² >0.30 cm² R Vol <15 ml 15-30 ml >30 ml RF <25% 25-45% >45% Abstract 38 Figure.

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Van Hulle, Suzanne, Issaka Sagara, Momar Mbodji, Ghislain Ismael Nana, Mamadou Coulibaly, Alassane Dicko, Mamady Kone et al. « Evaluation of the protective efficacy of a spatial repellent to reduce malaria incidence in children in Mali compared to placebo : study protocol for a cluster-randomized double-blinded control trial (the AEGIS program) ». Trials 23, n^o 1 (5 avril 2022). http://dx.doi.org/10.1186/s13063-022-06197-w.

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Abstract Background Spatial repellents have been widely used for the prevention of mosquito bites but their efficacy in reducing mosquito-borne diseases has never been evaluated in Africa. Additionally, spatial repellents have the potential of being critical tools in the prevention of mosquito-borne diseases in contexts where typical vectors control efforts such as insecticide-treated nets (ITNs) and indoor residual spray (IRS) are inaccessible or underutilized such as among displaced populations or in emergency relief settings. To address this knowledge gap, Kolondieba District, Sikasso Region, Mali was selected as a site to estimate the impact of the Mosquito Shield™, a spatial repellent that incorporates transfluthrin on a plastic sheet, on malaria-related outcomes. Over the past decade, the Region of Sikasso, Health districts of Kadiolo, Yorosso, and Kolondieba have remained among the most afflicted, characterized by an annual parasite incidence of more than 116 cases per 1000 population [1] and a Plasmodium falciparum prevalence rate of 29.7% [2]. Methods Cluster-randomized, placebo-controlled, double-blinded clinical trial, whereby children ≥ 6 months to < 10 years old will be enrolled and followed to determine the time to malaria infection with monthly blood samples for microscopic diagnosis. A total of 1920 subjects (HHs) will be enrolled in 60 clusters (30 spatial repellent, 30 placebo). Malaria incidence will be estimated and compared to demonstrate and quantify the protective efficacy (PE) of a spatial repellent, in reducing malaria infection. Monthly mosquito collections using CDC light traps will be conducted to determine if there are entomological correlates of spatial repellent efficacy that may be useful for the evaluation of new spatial repellents. Quarterly human landing catches (HLC) will assess the behavioral effects of the intervention. Discussion Findings will serve as an efficacy trial of spatial repellent products for sub-Saharan Africa. Findings will be submitted to the World Health Organization Vector Control Advisory Group (WHO VCAG) for assessment of whether spatial repellents have “public health value.” Entomological outcomes will also be measured as proxies of malaria transmission to help develop guidelines for the evaluation of future spatial repellent products. Trial registration ClinicalTrials.govNCT04795648. Registered on March 12, 2021.

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Reference Collection of Annual Meeting 2009.9 (2009) : 167–68. http://dx.doi.org/10.1299/jsmemecjsm.2009.9.0_167.

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Journal of the Japan Society for Precision Engineering 75, n^o 2 (2009) : 249–50. http://dx.doi.org/10.2493/jjspe.75.249.

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N’Guessan, Raphael, Serge-Brice Assi, Alphonsine Koffi, Phamien Ludovic Ahoua Alou, Anatole Mian, Nicole L. Achee, Benedicte Fustec et al. « EaveTubes for control of vector-borne diseases in Côte d’Ivoire : study protocol for a cluster randomized controlled trial ». Trials 24, n^o 1 (2 novembre 2023). http://dx.doi.org/10.1186/s13063-023-07639-9.

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Abstract Background Vector control tools, long-lasting insecticidal nets (LLINs) and indoor residual spraying (IRS), have significantly contributed to malaria prevention efforts in sub-Saharan Africa. However, insecticide resistance has seriously hampered their efficacy in recent years and new tools are essential to further progress. In2Care® EaveTubes (ETs) are an inexpensive, new resistance-breaking vector control product under World Health Organization (WHO) evaluation informed by mosquito ecology to efficiently target malaria vectors. By installing ETs in the walls of the house at the eave level that funnel the natural airflow, mosquitoes are drawn in by the same heat and odor cues that typically attract them through open eaves. Once inside an ET, mosquitoes are exposed to insecticide-treated netting placed inside the ET. The aim of this study is to test whether ETs as stand-alone tool have an effect on the epidemiology of malaria in villages where houses have been modified with the ET intervention. Methods A two-armed, cluster randomized controlled trial will be conducted to evaluate the effect of ETs on clinical malaria incidence in children living in Côte d’Ivoire. Thirty-four villages will be selected based on population size and the proportion of houses suitable for modification with ETs (17 treatment arms (ETs + LLINs, 17 control arms (LLINs only)). Based on the population census, 55 households per cluster with eligible children (i.e., between the ages of 6 months to 8 years old at the start of the study) will be randomly selected for recruitment into the active detection cohorts. In the treatment arm, we will enroll eligible children who reside in ET-treated houses. The intervention and control cohorts will be followed for 4 months for baseline covariate measurements and 24 months with intervention. During case detection visits, blood samples will be taken from all febrile children and tested for malaria infection with rapid diagnostic tests (RDTs). All positive clinical malaria infections will be treated. To estimate the impact of the ET on malaria vector densities, entomological measurements (indoor sampling with CDC traps) will be conducted monthly in 20 clusters (10 ET, 10 Control) in 10 randomly selected households per cluster. To estimate the infectiousness of malaria vectors, sporozoite rates will be measured in subsets of the collected mosquito samples. Discussion Findings will serve as an efficacy trial of ETs and will be submitted to the WHO Vector Control Advisory Group (VCAG) for assessment of public health value. Entomological outcomes will also be measured as proxies of malaria transmission to help develop guidelines for the evaluation of future In2Care® ETs products. Trial registration ClinicalTrials.gov NCT05736679. Registered on 10 February 2023.

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