Articles de revues : « Valle at risk »

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Calvache, Sorany, Lizeth Chazatar, Eliana Jiménez, Rosario Quiñónes, Milena Galvis et Sandra Moreno. « Risk Factors associated to BURNOUT Sindrome in dentistry students from University of Valle ». Revista Estomatología 21, n^o 1 (29 septembre 2017) : 7–11. http://dx.doi.org/10.25100/re.v21i1.5752.

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SUMMARYObjective: To determine the risk factorspredisposing to burnout syndrome instudents from Dentistry Program at theUniversity of Valle.Materials and Methods: In this cross-sectional study were enrolled 90 studentsin the period from February to June 2012in the academic program of Dentistry fromthe Universidad del Valle, who attend third,fourth and fifth year. The test Maslach BurnoutInventory (MBI) was applied whichconsists of 22 items with 7 response optionscorresponding to three basic dimensions ofburnout syndrome, emotional exhaustion(AE), depersonalization (D) and reducedpersonal or professional accomplishment(BR). Chi2 test were run for each of thefactors and Kruscal Wallis and ANOVAwere also applied.Results: The fifth graders scored an averageof 5.60 on a scale of depersonalization(D), which was statistically significant,indicating that there is a risk factor presentin this group of students. In this dimensionof depersonalization, values were lowerfor levels 1, 2, 3 and 6 but there was nostatistically significant differences betweenthem. Given the sub-scale of emotionalexhaustion (AE) the highest values wereassociated with socio-economic levels 3,4 and 5.Conclusions: Our results show that the academicload can be a predisposing factor thatimpacts mainly on the depersonalizationand manifests itself at the end of college.Socioeconomic variables, family environment,age, or spend a certain semesterdo not constitute specific risk factors fordevelopment of the syndrome. Key words: Burnout syndrome, emotionalexhaustion, depersonalization, personalaccomplishment.

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Interdonato, Monica, Alessandra Bitto, Gabriele Pizzino, Natasha Irrera, Giovanni Pallio, Anna Mecchio, Antonino Cuspilici, Letteria Minutoli, Domenica Altavilla et Francesco Squadrito. « Levels of Heavy Metals in Adolescents Living in the Industrialised Area of Milazzo-Valle del Mela (Northern Sicily) ». Journal of Environmental and Public Health 2014 (2014) : 1–9. http://dx.doi.org/10.1155/2014/326845.

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In the Milazzo-Valle del Mela area, the presence of industrial plants and the oil refinery make local residents concerned for their health. For this reason, we evaluated the levels of heavy metals in 226 children aged 12–14 years, living in the 7 municipalities of the area. A control age-matched population(n=29)living 45 km far from the industrial site was also enrolled. Arsenic, cadmium, chromium, mercury, nickel, and vanadium were analysed in 24 h urine samples, while lead concentration was evaluated in blood samples. A questionnaire regarding life style and risk perception was also administered. Adolescents from Milazzo-Valle del Mela had cadmium levels significantly higher compared to either controls (P<0.0001)or the reference values of the European Germany Environmental Survey (GerES-IV) and the American National Health and Nutrition Examination Survey (NHANES). Furthermore, children had higher perception of living in a high-risk environment. The present data, for the first time, clearly indicate that adolescents living in Milazzo-Valle del Mela have increased body concentration of cadmium, which may be harmful to human health. These results deserve particular attention by the local and regional government to initiate prevention programmes in this susceptible population.

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Gorini, Francesca, Elisa Bustaffa, Davide Bolignano, Liliana Cori, Francesco Faita, Amalia Gastaldelli, Monica Interdonato et al. « Biomarkers of exposure and early effect in three contaminated sites of southern Italy : protocols for etiological epidemiological studies ». BMJ Open 10, n^o 5 (mai 2020) : e036160. http://dx.doi.org/10.1136/bmjopen-2019-036160.

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IntroductionEnvironmental pollution has been progressively becoming one of the main risk factors to human diseases. In particular, populations living in high-contaminated sites are particularly exposed to environmental toxicants, with consequent increased risks to human health. In Italy, there are currently ongoing three epidemiological etiological studies aimed at evaluating the association between exposure to inorganic and organic chemicals and presence of biological markers of early effects in population living in three National Priority Contaminated Sites (NPCSs). Specifically, the correlations concern preclinical indicators of liver disease in Priolo NPCS, thyroid diseases in Milazzo-Valle del Mela NPCS and cardiovascular risk and kidney damage in Crotone NPCS.Methods and analysisOverall, approximately 1300 subjects of both sexes will be enrolled in the three NPCSs according to specific inclusion criteria. For each subject, serum and urine specimens are collected, on which the determination of biological markers of exposure and early effects for the selected outcomes are performed. Individual information on environmental and occupational exposure, medical history, diet and life habits is obtained through questionnaires provided by web platform. In Milazzo-Valle del Mela and Crotone NPCSs, not invasive instrumental and imaging examinations are performed in order to evaluate further risk factors of thyroid carcinoma and cardiovascular disease, respectively.Ethics and disseminationThe protocol studies have been approved by the Ethics Committees responsible for the three involved NPCSs: the Ethics Committee ‘Catania 2’ for the NPCS of Priolo (21 July 2017, n. 500/2017/CECT2), the Ethics Committee of the University Hospitals of Messina for the NPCS of Milazzo-Valle del Mela (19 February 2018, n.2/2018); the Ethics Committee of the Region of Calabria for the NPCS of Crotone (20 July 2017, n. 174). Results will be disseminated among policy-makers, citizens, stakeholders and scientific community through the organisation of conferences and events, and the publication on international peer/reviewed journals.

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Ratto, Sara, Franco Bonetto et Claudio Comoglio. « The October 2000 flooding in Valle d'Aosta (Italy) : Event description and land planning measures for the risk mitigation ». International Journal of River Basin Management 1, n^o 2 (juin 2003) : 105–16. http://dx.doi.org/10.1080/15715124.2003.9635197.

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BERNALTE, M. JOSEFA, M. TERESA HERNÁNDEZ, M. CARMEN VIDAL-ARAGÓN et EDUARDO SABIO. « PHYSICAL, CHEMICAL, FLAVOR AND SENSORY CHARACTERISTICS OF TWO SWEET CHERRY VARIETIES GROWN IN 'VALLE DEL JERTE' (SPAIN) ». Journal of Food Quality 22, n^o 4 (octobre 1999) : 403–16. http://dx.doi.org/10.1111/j.1745-4557.1999.tb00173.x.

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Vicedo-Cabrera, Ana M., Dolores Catelan, Laura Grisotto, Franca Rusconi, Neil Pearce, Fabio Barbone et Annibale Biggeri. « Respiratory disorders and air pollution in children living in the High Risk Area of Milazzo – Valle del Mela (Sicily). » ISEE Conference Abstracts 2013, n^o 1 (19 septembre 2013) : 3903. http://dx.doi.org/10.1289/isee.2013.p-1-05-32.

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Peña-Quistial, Magda Gileydi, Javier Antonio Benavides-Montaño, Nestor Javier Roncancio Duque et Gerardo Alejandro Benavides-Montaño. « Prevalence and associated risk factors of Intestinal parasites in rural high-mountain communities of the Valle del Cauca—Colombia ». PLOS Neglected Tropical Diseases 14, n^o 10 (9 octobre 2020) : e0008734. http://dx.doi.org/10.1371/journal.pntd.0008734.

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Byczkowska, Katarzyna. « Katz Frailty Syndrom has no Predictive Value in Low-Risk Patients Undergoing Transcatheter Aortic Valve Implantation ». Clinical Cardiology and Cardiovascular Interventions 04, n^o 16 (12 octobre 2021) : 01–08. http://dx.doi.org/10.31579/2641-0419/227.

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Background: Aortic stenosis is a disease of the elderly people, with multiple comorbidities and often with the frailty syndrome. Therefore, we decided that frailty as a clinical factor requires precise characterization as it is a valuable supplement to the risk stratification in transcatheter aortic Valve implantation (TAVI). Objective: The aim of our study was to evaluate the prognostic value of the Katz frailty scale in patients undergoing TAVI in relation to the risk of mortality assessed with the STS scale. Material and methods: The study included 105 patients with severe aortic stenosis (AS) treated with TAVI at the Department of Invasive Cardiology, Central Clinical Hospital of the Ministry of Interior. In our group, the Katz frailty syndrome confirmed in all patients, and 48% in the advanced stage. Results: Statistical analysis showed a significant difference between survival and Katz frailty score before TAVI. Analysis using Cox's model confirmed a significant prognostic value for the Katz frailty syndrome before TAVI. Patients with moderate to severe frailty on the Katz score (values ≤ 4) had a 13,68 times higher risk of death per year compared to the group with Katz frailty syndrome ≥ 5. Multivariate regression analysis indicated that Katz frailty score and STS score were prognostically significant factors of cardiovascular death in patients undergoing TAVI. Conclusion: The Katz frailty score had a significant prognostic value in the high- and intermediate risk patients. Katz frailty score and STS risk score significantly correlated with the risk of death from cardiovascular causes in frailty patients undergoing TAVI.

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Wilhelm, Bruno, Hendrik Vogel et Flavio S. Anselmetti. « A multi-centennial record of past floods and earthquakes in Valle d'Aosta, Mediterranean Italian Alps ». Natural Hazards and Earth System Sciences 17, n^o 5 (8 mai 2017) : 613–25. http://dx.doi.org/10.5194/nhess-17-613-2017.

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Abstract. Mediterranean Alpine populations are particularly exposed to natural hazards like floods and earthquakes because of both the close Mediterranean humidity source and the seismically active Alpine region. Knowledge of long-term variability in flood and earthquake occurrences is of high value since it can be useful to improve risk assessment and mitigation. In this context, we explore the potential of a lake-sediment sequence from Lago Inferiore de Laures in Valle d'Aosta (Northern Italy) as a long-term record of past floods and earthquakes. The high-resolution sedimentological study revealed 76 event layers over the last ca. 270 years; 8 are interpreted as most probably induced by earthquakes and 68 by flood events. Comparison to historical seismic data suggests that the recorded earthquakes are strong (epicentral Medvedev–Sponheuer–Kárník (MSK) intensity of VI–IX) and/or close to the lake (distance of 25–120 km). Compared to other lake-sediment sequences, Lago Inferiore de Laures sediments appear to be regionally the most sensitive to earthquake shaking, offering a great potential to reconstruct the past regional seismicity further back in time. Comparison to historical and palaeoflood records suggests that the flood signal reconstructed from Lago Inferiore de Laures sediments represents the regional and (multi-)decadal variability of summer–autumn floods well, in connection to Mediterranean mesoscale precipitation events. Overall, our results reveal the high potential of Lago Inferiore de Laures sediments to extend the regional earthquake and flood catalogues far back in time.

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Zelinková, Kateřina, et Aleš Kresta. « DETERMINATION OF VALUE AT RISK AND CONDITIONAL VALUE AT RISK BY ASSUMING ELLIPTICAL DISTRIBITION ». Acta academica karviniensia 16, n^o 2 (30 juin 2016) : 95–105. http://dx.doi.org/10.25142/aak.2016.017.

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Casteller, Alejandro, Thomas Häfelfinger, Erika Cortés Donoso, Karen Podvin, Dominik Kulakowski et Peter Bebi. « Assessing the interaction between mountain forests and snow avalanches at Nevados de Chillán, Chile and its implications for ecosystem-based disaster risk reduction ». Natural Hazards and Earth System Sciences 18, n^o 4 (18 avril 2018) : 1173–86. http://dx.doi.org/10.5194/nhess-18-1173-2018.

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Abstract. Gravitational natural hazards such as snow avalanches, rockfalls, shallow landslides and volcanic activity represent a risk to mountain communities around the world. In particular, where documentary records about these processes are rare, decisions on risk management and land-use planning have to be based on a variety of other sources including vegetation, tree-ring data and natural hazard process models. We used a combination of these methods in order to evaluate dynamics of natural hazards with a focus on snow avalanches at Valle Las Trancas, in the Biobío region in Chile. Along this valley, natural hazards threaten not only the local human population, but also the numerous tourists attracted by outdoor recreational activities. Given the regional scarcity of documentary records, tree-ring methods were applied in order to reconstruct the local history of snow avalanches and debris flow events, which are the most important weather-related processes at respective tracks. A recent version of the model Rapid Mass MovementS (RAMMS), which includes influences of forest structure, was used to calculate different avalanche parameters such as runout distances and maximum pressures, taking into consideration the presence or absence of forest along the tracks as well as different modeled return periods. Our results show that local Nothofagus broadleaf forests contribute to a reduction of avalanche runout distances as well as impact pressure on present infrastructure, thus constituting a valuable ecosystem disaster risk reduction measure that can substitute or complement other traditional measures such as snow sheds.

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Mendoza-Espinosa, L. G., A. Cabello-Pasini, V. Macias-Carranza, W. Daessle-Heuser, M. V. Orozco-Borbón et A. L. Quintanilla-Montoya. « The effect of reclaimed wastewater on the quality and growth of grapevines ». Water Science and Technology 57, n^o 9 (1 mai 2008) : 1445–50. http://dx.doi.org/10.2166/wst.2008.242.

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The effect of the use of treated wastewater on the growth of cabernet sauvignon and merlot grapes from the Guadalupe Valley, Mexico was evaluated. Secondary advanced effluent was used to irrigate the grapevines at a rate of 66 L/vine/week. Wastewater quality results confirmed that all parameters complied with Mexican legislation for crop irrigation as well as reuse in activities in which the public would be in direct or indirect contact with the reclaimed water. Results showed that the number of leaves per shoot and the overall biomass increased in plants irrigated with wastewater and grape production per plant was 20% higher. The concentration of carbohydrates, organic acids and pH were similar in grapes from vines irrigated with wastewater to those irrigated with groundwater. Throughout the experiment, no fecal coliform bacteria were detected in the cultivated grapes. The wastewater caused an increase in the biomass of the grapevines and there was no presence of microbial indicators in the final product so a higher wine production could be achieved without an increase in health risk related problems. If 200 L/s of reclaimed wastewater would be returned to be used for grapevine irrigation in Valle de Guadalupe (the same amount that is currently being sent as drinking water to Ensenada), assuming an irrigation application of 6,000–7.500 m3/ha/year, approximately 837–1046 hectares (ha) of grapevines could be irrigated. Part of ongoing research includes an economical analysis of the best options for Ensenada and the Valle de Guadalupe in order to establish the optimum volume of water to be returned, the cost of its transportation, as well as the cost of irrigation.

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Misankova, Maria, et Erika Spuchlakova. « Application of conditional value at risk for credit risk optimization ». New Trends and Issues Proceedings on Humanities and Social Sciences 3, n^o 4 (22 mars 2017) : 146–52. http://dx.doi.org/10.18844/gjhss.v3i4.1540.

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Duran, Carlos E., Alejandro Ramírez, Juan G. Posada, Johanna Schweineberg, Liliana Mesa, Harry Pachajoa, Mayra Estacio et al. « Prevalence of APOL1 Risk Variants in Afro-Descendant Patients with Chronic Kidney Disease in a Latin American Country ». International Journal of Nephrology 2019 (18 décembre 2019) : 1–5. http://dx.doi.org/10.1155/2019/7076326.

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Introduction. In Colombia, the genetic background of the populations was shaped by different levels of admixture between Natives, European, and Africans. Approximately 35.363 patients have diagnosed chronic kidney disease and according to population studies, 10.4% of these patients are Afro-descendant. We aim to assess the frequency of APOL1 variants G1 and G2 in Afro-descendant patients with ESRD treated at la Fundacion Valle del Lili University Hospital in Cali, Colombia. Methods. This is an observational cross-sectional study. Afro-descendant patients with ESRD in waitlist or recipients of kidney transplant were evaluated. Clinical data were collected from the electronic medical records. Genotyping was carried out by amplification of the exon 7 of the APOL1 gene. For the identification of risk genotypes, the bioinformatics tool BLAST was used. Results. We enrolled 102 participants. The frequency of APOL1 risk variants was 67.2%, in which 24.5% (n = 25) were G1 heterozygous and 5.8% (n = 6) were G2 heterozygous and 37% of the patients had high-risk status with two alleles in homozygous (G1/G1 = 21 and G2/G2 = 3) or compound heterozygote (G1/G2 = 14) form.

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Angelidis, Timotheos, et Alexandros Benos. « Value-at-Risk for Greek Stocks ». Multinational Finance Journal 12, n^o 1/2 (1 juin 2008) : 67–104. http://dx.doi.org/10.17578/12-1/2-4.

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Hwang, Jaehak. « Climate Value at Risk of Korean corporations ». Journal of Market Economy 51, n^o 3 (31 octobre 2022) : 57–84. http://dx.doi.org/10.38162/jome.51.3.3.

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Carlos, Marina Moraes, Carmencita Ignatti et Marcelo Ricardo Rosa. « Leishmaniose tegumentar americana : incidência no Vale do Ribeira/São Paulo, Brasil ». Revista Recien - Revista Científica de Enfermagem, n^o 15 (15 décembre 2015) : 3. http://dx.doi.org/10.24276/2358-3088.2015.5.15.3-10.

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A leishmaniose é considerada uma doença negligenciada e cerca de 400 milhões de pessoas estão sob risco de infectividade. O Vale do Ribeira, localizado no estado de São Paulo é um local que favorece a presença de flebotomíneos, vetores de Leishmania, razão pela qual a maioria dos municípios do Vale do Ribeira apresenta vetores para essa doença. Esse artigo objetiva revisar características epidemiológicas da doença e salientar alguns estudos de leishmaniose tegumentar americana na região do Vale do Ribeira. De acordo com os estudos, percebe-se que o combate a transmissão das leishmanioses tegumentares é difícil, já que a ocorrência da doença está relacionada a um baixo desenvolvimento humano, a fatores sociais, econômicos, políticos e culturais. E assim, a prevenção da doença envolve várias ações preventivas (efetivas), que devem ser flexíveis e específicas a cada região endêmica tendo em consideração particularidades de cada espaço físico.Descritores: Enfermagem, Leishmaniose Tegumentar, Protozoários. Leishmaniasis american: impact your in Ribeira Valley/Sao Paulo, Brazil Abstract: The leishmaniasis is considered a neglected disease and around 400 million people are at risk of infectivity. The Ribeira Valley, located in the state of Sao Paulo is a place that favors the presence of phlebotomines, vectors of Leishmania, why the majority of the municipalities of the Ribeira Valley presents vectors for this disease. This article aims to review the epidemiological characteristics of the disease and emphasize some studies of american tegumentary leishmaniasis in the region of the Ribeira Valley. According to the studies, it is perceived that the fight against the transmission of tegumentary leishmaniasis is difficult, since the occurrence of the disease is related to a low human development, social factors, economic, political and cultural rights. And thus the prevention of the disease involves various preventive actions (effective), which should be flexible and specific to each endemic region taking into account the particularities of each physical space.Descriptors: Nursing, Tegumentary Leishmaniasis, Protozoa.Tegumentaria americana leishamaniasis: impacto en el Valle de Ribeira/São Paulo, Brasil Resumen: La leishmaniasis es considerada una enfermedad desatendida y alrededor de 400 millones de personas están en riesgo de contagio. El Valle de Ribeira, situado en el estado de São Paulo es un lugar que favorece la presencia de phlebotomines, vectores de Leishmania, razón por la que la mayoría de los municipios del valle del Ribeira, presenta los vectores de esta enfermedad. Este artículo pretende revisar las características epidemiológicas de la enfermedad y resaltar algunos estudios de leishmaniasis tegumentaria americana en la región del Vale do Ribeira. Según los estudios, se considera que la lucha contra la transmisión de la leishmaniasis tegumentaria es difícil, desde la aparición de la enfermedad está relacionada con un bajo índice de desarrollo humano, los factores sociales, económicos, políticos y culturales. Y, por tanto, la prevención de la enfermedad involucra diversas acciones preventivas (efectiva), que deberían ser flexibles y específicas para cada región endémica teniendo en cuenta las particularidades de cada espacio físico.Descriptores: Enfermería, Leishmaniasis Tegumentaria, Protozoos.

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Carlos, Marina Moraes, Carmencita Ignatti et Marcelo Ricardo Rosa. « Leishmaniose tegumentar americana : incidência no Vale do Ribeira/São Paulo, Brasil ». Revista Recien - Revista Científica de Enfermagem 5, n^o 15 (15 décembre 2015) : 3. http://dx.doi.org/10.24276/rrecien2358-3088.2015.5.15.3-10.

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A leishmaniose é considerada uma doença negligenciada e cerca de 400 milhões de pessoas estão sob risco de infectividade. O Vale do Ribeira, localizado no estado de São Paulo é um local que favorece a presença de flebotomíneos, vetores de Leishmania, razão pela qual a maioria dos municípios do Vale do Ribeira apresenta vetores para essa doença. Esse artigo objetiva revisar características epidemiológicas da doença e salientar alguns estudos de leishmaniose tegumentar americana na região do Vale do Ribeira. De acordo com os estudos, percebe-se que o combate a transmissão das leishmanioses tegumentares é difícil, já que a ocorrência da doença está relacionada a um baixo desenvolvimento humano, a fatores sociais, econômicos, políticos e culturais. E assim, a prevenção da doença envolve várias ações preventivas (efetivas), que devem ser flexíveis e específicas a cada região endêmica tendo em consideração particularidades de cada espaço físico.Descritores: Enfermagem, Leishmaniose Tegumentar, Protozoários. Leishmaniasis american: impact your in Ribeira Valley/Sao Paulo, Brazil Abstract: The leishmaniasis is considered a neglected disease and around 400 million people are at risk of infectivity. The Ribeira Valley, located in the state of Sao Paulo is a place that favors the presence of phlebotomines, vectors of Leishmania, why the majority of the municipalities of the Ribeira Valley presents vectors for this disease. This article aims to review the epidemiological characteristics of the disease and emphasize some studies of american tegumentary leishmaniasis in the region of the Ribeira Valley. According to the studies, it is perceived that the fight against the transmission of tegumentary leishmaniasis is difficult, since the occurrence of the disease is related to a low human development, social factors, economic, political and cultural rights. And thus the prevention of the disease involves various preventive actions (effective), which should be flexible and specific to each endemic region taking into account the particularities of each physical space.Descriptors: Nursing, Tegumentary Leishmaniasis, Protozoa.Tegumentaria americana leishamaniasis: impacto en el Valle de Ribeira/São Paulo, Brasil Resumen: La leishmaniasis es considerada una enfermedad desatendida y alrededor de 400 millones de personas están en riesgo de contagio. El Valle de Ribeira, situado en el estado de São Paulo es un lugar que favorece la presencia de phlebotomines, vectores de Leishmania, razón por la que la mayoría de los municipios del valle del Ribeira, presenta los vectores de esta enfermedad. Este artículo pretende revisar las características epidemiológicas de la enfermedad y resaltar algunos estudios de leishmaniasis tegumentaria americana en la región del Vale do Ribeira. Según los estudios, se considera que la lucha contra la transmisión de la leishmaniasis tegumentaria es difícil, desde la aparición de la enfermedad está relacionada con un bajo índice de desarrollo humano, los factores sociales, económicos, políticos y culturales. Y, por tanto, la prevención de la enfermedad involucra diversas acciones preventivas (efectiva), que deberían ser flexibles y específicas para cada región endémica teniendo en cuenta las particularidades de cada espacio físico.Descriptores: Enfermería, Leishmaniasis Tegumentaria, Protozoos.

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Biggeri, Annibale, Dolores Catelan, Gaetano Dongarrà, Daniela Varrica, Daniele Grechi, Franca Rusconi, Riccardo Pistelli, Fabio Barbone et Neil Pearce. « ASTHMA SYMPTOMS AND METAL COMPOSITION OF FINE PARTICLE AIR POLLUTION. PANEL STUDY IN CHILDREN LIVING IN THE MILAZZO–VALLE DEL MELA (ITALY) HIGH-RISK AREA ». ISEE Conference Abstracts 2013, n^o 1 (19 septembre 2013) : 5320. http://dx.doi.org/10.1289/isee.2013.o-4-14-03.

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Lamouroux-López, Sandra, Merling López et Hector Ricardo Flores Gatica. « Parámetros biológicos básicos para la conservación de Pseudocurimata lineopunctata (Characiformes, Curimatidae) en el Río Anchicayá, Valle del Cauca, Colombia ». Revista de Biología Tropical 65, n^o 1 (3 novembre 2016) : 239. http://dx.doi.org/10.15517/rbt.v65i1.22817.

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Pseudocurimata lineopunctata represents an important nutritional source for local human communities in Colombia and Ecuador. Although the yearly catch of this fish is low (590 kg/year), there are no restrictions on minimum size, and this species is categorized as vulnerable with moderate extinction risk by the Regional Autonomous Corporation of the Cauca Valley (Colombia). To support conservation programs, biological data of the target species are required. Therefore, the aims of this study were to describe the sex ratio, distribution, size to weight ratio, macroscopic stages of reproductive maturity, fecundity, and size at first sexual maturity for P. lineopunctata. For this, fish samples were captured with nets over nine months (February-October) in 2007. The total length (Lt) of the captured fish ranged between 10.7 and 16.5 cm, with total weight (Pt) between 25.0 and 67.5 g. Females represented 52.6 % of the sample group while males represented 47.4 %, and differences in sex ratio were observed in relation to fish size. For all sampled months, the fish captured showed an advanced maturity state. Based on analyses of the gonadosomatic index (IGS), gonadic index (IG), and Fulton’s condition factor (K), and two spawning peaks were determined, one in June-July, and the other in September-October. The size at first sexual maturity was 9.2 cm for females and 10.1 cm for males. Absolute fecundity was estimated as 3 598 oocytes/g♀. It is necessary to carry out additional investigations on the reproduction of this species, to support future repopulation programs.

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Stuchlíková, Zuzana. « Value-at-Risk and Dynamic Risk Measures ». Acta Oeconomica Pragensia 13, n^o 1 (1 mars 2005) : 63–68. http://dx.doi.org/10.18267/j.aop.137.

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von Balduin, Alexander. « Was ist der„Value at Risk” ? » RISKNEWS 1, n^o 2 (avril 2004) : 50–51. http://dx.doi.org/10.1002/risk.200490034.

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Ghizzoni, T., M. Lomazzi, G. Roth et R. Rudari. « Regional scale analysis of the altimetric stream network evolution ». Advances in Geosciences 7 (25 janvier 2006) : 79–83. http://dx.doi.org/10.5194/adgeo-7-79-2006.

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Abstract. Floods result from the limited carrying capacity of stream channels when compared to the discharge peak value. The transit of flood waves - with the associated erosion and sedimentation processes - often modifies local stream geometry. In some cases this results in a reduction of the stream carrying capacity, and consequently in an enhancement of the flooding risk. A mathematical model for the prediction of potential altimetric stream network evolution due to erosion and sedimentation processes is here formalized. It works at the regional scale, identifying the tendency of river segments to sedimentation, stability, or erosion. The model builds on geomorphologic concepts, and derives its parameters from extensive surveys. As a case study, tendencies of rivers pertaining to the Valle d'Aosta region are analyzed. Some validation is provided both at regional and local scales of analysis. Local validation is performed both through a mathematical model able to simulate the temporal evolution of the stream profile, and through comparison of the prediction with ante and post-event river surveys, where available. Overall results are strongly encouraging. Possible use of the information derived from the model in the context of flood and landslide hazard mitigation is briefly discussed.

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Cante, Domenico, Edoardo Petrucci, Cristina Piva, Valeria Casanova Borca, Piera Sciacero, Maurizio Bertodatto, Caterina Marta et al. « Delineation of the larynx as organ at risk in radiotherapy : a contouring course within “Rete Oncologica Piemonte-Valle d’Aosta” network to reduce inter- and intraobserver variability ». La radiologia medica 121, n^o 11 (15 juillet 2016) : 867–72. http://dx.doi.org/10.1007/s11547-016-0668-8.

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Guzmán, Guillermo E., Angela M. Victoria, Isabella Ramos, Alejandro Maldonado, Eliana Manzi, Juan F. Contreras-Valero, Liliana Mesa et al. « Risk Factors Related to New-Onset Diabetes after Renal Transplantation in Patients of a High Complexity University Hospital in Colombia, 20 Years of Experience ». International Journal of Endocrinology 2020 (30 août 2020) : 1–5. http://dx.doi.org/10.1155/2020/8297192.

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Introduction. New-onset diabetes after transplantation (NODAT) is associated with immunosuppression. Its complications can negatively influence patients’ quality of life, which is why it is important to study the associated risk factors and expand the possible therapies in this particular group of patients. Materials and methods. Case-control study nested in a retrospective cohort. It included patients who received kidney transplantation at the high complexity University Hospital Fundación Valle del Lili in Cali, Colombia, between 1995 and 2014. Two controls were assigned for each case, depending on the type of donor and the date of the surgery. Information was collected from clinical records and the institutional TRENAL registry. We carried out a descriptive analysis of the selected variables and identified the risk factors with conditional logistic regression. Results. 122 cases were identified to which 224 controls were assigned. The median age was 44 years (IQR: 34–55), and 54% were men. Having >50 years of age at the time of transplantation (OR: 3.18, 95% CI: 1.6−6.3, p = 0.001), body mass index >30 kg/m2 (OR: 3.6, 95% CI: 1.3−9.7, p = 0.010) and being afro-descendant (OR: 2.74, 95% CI: 1.1−6.5, p = 0.023) were identified as risk factors for the development of NODAT. Pretransplant fasting plasma glucose >100 mg/dl (OR: 2.9, 95% CI: 1.4−6.4, p = 0.005) and serum triglycerides >200 mg/dl (OR: 2.5, 95% CI: 1.4−4.4, p = 0.002) were also reported as independent risk factors. Conclusion. We ratify some risk factors for the development of this important disease, which include certain modifiable characteristics. Interventions aimed at changes in lifestyle could be established in a timely manner before transplant surgery.

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Kountur, Ronny. « The likelihood value of residual risk estimation in the management of enterprise risk ». Investment Management and Financial Innovations 15, n^o 3 (13 juillet 2018) : 49–55. http://dx.doi.org/10.21511/imfi.15(3).2018.04.

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A model for estimating the likelihood value of residual risk (Y) is introduced. The model consists of three independent variables: the likelihood value of risk before risk treatment (X1), the quality of risk treatment (X2), and the appropriateness of risk treatment (X3). An experimental research design with a multiple linear regression analysis was used in the estimation. All independent variables, the likelihood value of risk before treatment, the quality of risk treatment, and the appropriateness of risk treatment, can be significantly used to estimate the likelihood value of residual risk. Since no model of estimating residual risk of likelihood had been introduced yet, the findings of this study provide significant contribution to firms or organizations that need to assess the likelihood value of residual risks.

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Mangiero, Susan M. « Risk2 : Measuring the Risk in Value at Risk ». CFA Digest 27, n^o 3 (août 1997) : 68–69. http://dx.doi.org/10.2469/dig.v27.n3.125.

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Jorion, Philippe. « Risk2 : Measuring the Risk in Value at Risk ». Financial Analysts Journal 52, n^o 6 (novembre 1996) : 47–56. http://dx.doi.org/10.2469/faj.v52.n6.2039.

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Bolaños Portilla, Isabel Cristina, Isabel Cristina Hurtado Sánchez et Inés Restrepo Tarquino. « Diffuse cognitive maps for analysis of vulnerability to climate variability in Andean rural micro-watersheds ». DYNA 87, n^o 212 (1 janvier 2020) : 38–46. http://dx.doi.org/10.15446/dyna.v87n212.79943.

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Diffuse cognitive map was applied to analyse factors of vulnerability to climate variability in rural Andean micro-watershed. The iModeler software was used as a tool that allows the modelling of these maps. As input information, the results of the socioecological dynamics analysis previously implemented in the case study were taken, and weights were assigned to each input factor in relation to a central factor in a time scale. The model applied in the El Chocho micro-watershed - Department of Valle del Cauca in Colombia, can be validated in similar contexts of the Andean Colombian area. A high degree of water shortage and increased pressure on the associated ecosystems was evidenced, which puts at risk the resilience of the socio-ecosystem to face climate variability. The results of this type of models are tools for decision making in adaptation at rural level.

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García Torres, Adrián. « La inundación de 1714 de la Ciudad de México : impacto, consecuencias y dicotomía entre riesgos naturales e intereses económicos ». Cuadernos de Estudios del Siglo XVIII, n^o 29 (17 décembre 2019) : 153–79. http://dx.doi.org/10.17811/cesxviii.29.2019.153-179.

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RESUMENLa Ciudad de México es un ejemplo paradigmático de un asentamiento en un territorio en riesgo. Durante el periodo colonial, los cambios ecológicos que en el valle de México se produjeron tuvieron como consecuencia un aumento en la frecuencia e intensidad de las inundaciones. En nuestra contribución analizamos el impacto que tuvo el evento de inundación de 1714, sus causas y las decisiones que se tomaron por las autoridades civiles para la reconstrucción y la prevención. Especialmente dedicamos un importante interés al conflicto que hubo en Nuestra Señora de Guadalupe debido a las modificaciones del cauce del río Guadalupe por la Hacienda de Santa Ana Aragón, que provocaron el anegamiento de la población.PALABRAS CLAVECiudad de México, inundaciones, desastre, siglo XVIII, ciencia y técnica. TITLEThe fl ood of 1714 in Mexico City: a paradigmatic example of the dichotomy between natural risks and economic interestsABSTRACTMexico City is a paradigmatic example of a settlement in a territory at risk. During the colonial period, the ecological changes that occurred in the Valley of Mexico resulted in an increase in the frequency and intensity of floods. In our contribution we analyze the impact that the flood event of 1714 had, its causes and the decisions that were made bythe civil authorities for the reconstruction and the prevention. Especially we dedicate an important interest to the conflict that there was in Nuestra Señora of Guadalupe due to the modifications of the course of the Guadalupe River by the Hacienda of Santa Ana Aragón, that caused the flood of the village.KEY WORDSMexico City, floods, disaster, 18th century, science and technology.

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Stefaniak, Radosław. « REVIEW OF VALUE AT RISK ESTIMATION METHODS ». PRACE NAUKOWE UNIWERSYTETU EKONOMICZNEGO WE WROCŁAWIU, n^o 519 (2018) : 173–83. http://dx.doi.org/10.15611/pn.2018.519.14.

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Fusco, V., C. Ortega, F. Goia, L. Ciuffreda, M. Ardine, P. Falco, G. Gorzeglio, A. Baraldi, M. Airoldi et O. Bertetto. « Bisphosphonates (BP)-related osteonecrosis of the jaw (ONJ) : Clinical experience of the “Rete Oncologica di Piemonte e Valle d’Aosta” network ». Journal of Clinical Oncology 24, n^o 18_suppl (20 juin 2006) : 18584. http://dx.doi.org/10.1200/jco.2006.24.18_suppl.18584.

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18584 Background: ONJ have been recently reported in patients (pts) treated with BP, especially Pamidronate (P) and Zoledronic Acid (Z). Measures of screening, treatment, and prevention have been planned in our regional oncology network. Methods: We evaluated dental history of pts previously treated with BP and/or under treatment in 2005, finding 60 cases of ONJ, but a large number of suspected cases are under investigation/observation. Full details of oncologic and dental history have been collected so far of 43 pts. Results: Pts characteristics: sex: 14/29 M/F; median age 66 years (range 45–81); tumour: 24 breast cancer, 7 prostate cancer; 12 myeloma. BP treatment: 5 P, 14 P changed to Z, 24 Z; median number of infusions: 22 of P (range 12–52), 18 of Z (range 7–43). Site of ONJ: 33 (77%) in mandible, 9 (21%) in maxilla, 1 (2%) in both. Presenting findings included exposed bone or infections (95%), pain, mobile teeth, soft-tissue swelling, nonhealing fistulas . Dental comorbidities were present in all pts and 92 % had precipitating events, as teeth extraction, periodontal surgery, dental implants, or traumatic use of dentures. Conclusions: Our oncology network planned: a) review of all pts treated with BP since 2000, to obtain real estimates of frequency and of possible risk factors; b) screening of all pts under treatment with BP, with panoramic X-rays and maxillofacial surgeon visit (w/o CT or MR scan in selected cases); c) careful evaluation of pts candidate to be treated with BP (as above), with pretherapy dental care if necessary; d) prospective evaluation of incidence in future, after pretherapy dental care policy and avoiding (as possible) surgical dental procedures during BP treatment; e) prospective trials of evaluation of palliative treatment of ONJ and related complications in affected pts (chlorohexidine mouthwashes, antibiotics, metronidazole, hyperbaric oxygen, etc.). No significant financial relationships to disclose.

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Lysaniuk, Benjamin, María Fernanda Cely-García, Margarita Giraldo, Joan M. Larrahondo, Laura Marcela Serrano-Calderón, Juan Carlos Guerrero-Bernal, Leonardo Briceno-Ayala, Esteban Cruz Rodriguez et Juan Pablo Ramos-Bonilla. « Using GIS to Estimate Population at Risk Because of Residence Proximity to Asbestos Processing Facilities in Colombia ». International Journal of Environmental Research and Public Health 18, n^o 24 (17 décembre 2021) : 13297. http://dx.doi.org/10.3390/ijerph182413297.

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The recent enactment of the law banning asbestos in Colombia raises a significant number of challenges. The largest factories that have historically processed asbestos include five asbestos-cement facilities located in the cities of Sibaté (Cundinamarca), Cali (Valle del Cauca), and Barranquilla (Atlántico), and Manizales (Caldas), which has two, as well as a friction products facility in Bogotá D.C. An asbestos chrysotile mine has also operated in Colombia since 1980 in Campamento (Antioquia). In the framework of developing the National Asbestos Profile for Colombia, in this study, we estimated the population residing in the vicinity of asbestos processing plants or the mine and, therefore, potentially at risk of disease. Using a geographic information system, demographic data obtained from the last two general population censuses were processed to determine the number of people living within the concentric circles surrounding the asbestos facilities and the mine. In previous studies conducted in different countries of the world, an increased risk of asbestos-related diseases has been reported for people living at different distance bands from asbestos processing facilities. Based on these studies, circles of 500, 1000, 2000, 5000, and 10,000 m radii, centered on the asbestos processing facilities and the mine that operated in Colombia, were combined with the census data to estimate the number of people living within these radii. Large numbers of people were identified. It is estimated that in 2005, at the country level, 10,489 people lived within 500 m of an asbestos processing facility or mine. In 2018, and within a distance of 10,000 m, the number of people was 6,724,677. This information can aid public health surveillance strategies.

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Tumino, Serena, Marco Tolone, Paola Galluzzo, Sergio Migliore, Tiziana Sechi, Salvatore Bordonaro, Roberto Puleio, Antonello Carta et Guido Ruggero Loria. « Alternative Molecular Tools for the Fight against Infectious Diseases of Small Ruminants : Native Sicilian Sheep Breeds and Maedi-Visna Genetic Susceptibility ». Animals 12, n^o 13 (24 juin 2022) : 1630. http://dx.doi.org/10.3390/ani12131630.

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Maedi-visna (MV) is a disease caused by small ruminant lentiviruses. It is included in the list of notifiable terrestrial animal diseases due to economic losses and animal welfare harm in the sheep sector. To date, control programs remain the onliest approach to avoiding infection. The allelic variant p.Glu35Lys (E35K) of the TMEM154 gene has been strongly associated with host vulnerability to MV illness. The present study aimed to investigate the association of TMEM154 E35K allele frequencies with MV susceptibility in native Sicilian sheep breeds. More than 400 animals from 14 local sheep were serologically tested and genotyped for the TMEM154 E35K polymorphism. The local breeds displayed different values of MV seroprevalence, with the lowest antibody prevalence in Barbaresca and Pinzirita breeds. TMEM154 protective allele (K35) was less frequent than the risk allele (E35) in Valle del Belìce breed, whereas the other three breeds showed a more balanced alleles distribution. A positive association between seroprevalence and genotype was found in the entire sample set. The risk of infection resulted in more than 3-fold times as high in sheep with EK and EE genotype compared to the KK genotype. Our data could be helpful in establishing selection breeding programs aimed at reducing MV infection in Sicilian sheep farming and encouraging the breeding of native breeds.

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Iovine, G., S. Di Gregorio et V. Lupiano. « Debris-flow susceptibility assessment through cellular automata modeling : an example from 15–16 December 1999 disaster at Cervinara and San Martino Valle Caudina (Campania, southern Italy) ». Natural Hazards and Earth System Sciences 3, n^o 5 (31 octobre 2003) : 457–68. http://dx.doi.org/10.5194/nhess-3-457-2003.

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Abstract. On 15–16 December 1999, heavy rainfall severely stroke Campania region (southern Italy), triggering numerous debris flows on the slopes of the San Martino Valle Caudina-Cervinara area. Soil slips originated within the weathered volcaniclastic mantle of soil cover overlying the carbonate skeleton of the massif. Debris slides turned into fast flowing mixtures of matrix and large blocks, downslope eroding the soil cover and increasing their original volume. At the base of the slopes, debris flows impacted on the urban areas, causing victims and severe destruction (Vittori et al., 2000). Starting from a recent study on landslide risk conditions in Campania, carried out by the Regional Authority (PAI –Hydrogeological setting plan, in press), an evaluation of the debris-flow susceptibility has been performed for selected areas of the above mentioned villages. According to that study, such zones would be in fact characterised by the highest risk levels within the administrative boundaries of the same villages ("HR-zones"). Our susceptibility analysis has been performed by applying SCIDDICA S3–hex – a hexagonal Cellular Automata model (von Neumann, 1966), specifically developed for simulating the spatial evolution of debris flows (Iovine et al., 2002). In order to apply the model to a given study area, detailed topographic data and a map of the erodable soil cover overlying the bedrock of the massif must be provided (as input matrices); moreover, extent and location of landslide source must also be given. Real landslides, selected among those triggered on winter 1999, have first been utilised for calibrating SCIDDICA S3–hex and for defining "optimal" values for parameters. Calibration has been carried out with a GIS tool, by quantitatively comparing simulations with actual cases: optimal values correspond to best simulations. Through geological evaluations, source locations of new phenomena have then been hypothesised within the HR-zones. Initial volume for these new cases has been estimated by considering the actual statistics of the 1999 landslides. Finally, by merging the results of simulations, a deterministic susceptibility zonation of the considered area has been obtained. In this paper, aiming at illustrating the potential for debris-flow hazard analyses of the model SCIDDICA S3–hex, a methodological example of susceptibility zonation of the Vallicelle HR-zone is presented.

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Enciso, Karen, Mauricio Sotelo, Michael Peters et Stefan Burkart. « The inclusion of Leucaena diversifolia in a Colombian beef cattle production system : An economic perspective ». Tropical Grasslands-Forrajes Tropicales 7, n^o 4 (3 septembre 2019) : 359–69. http://dx.doi.org/10.17138/tgft(7)359-369.

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Keynote paper presented at the International Leucaena Conference, 1‒3 November 2018, Brisbane, Queensland, Australia.Despite the great potential of legumes in cattle production, their adoption and use throughout the tropical world remain limited. While this is largely attributed to factors such as limited knowledge or access to credit, lack of information on the viability and profitability of the technology can influence the adoption decision. The objective of this study is to evaluate the profitability of including Leucaena diversifolia, accession ILRI 15551 in a Colombian beef cattle production system. For this purpose, we use data from a grazing experiment comparing a grass-legume association (Brachiaria hybrid cv. Cayman and L. diversifolia) with a grass monoculture (cv. Cayman) in the Valle del Cauca department, both with the purpose of beef production. We use a discounted cash flow model, developed with the simulation software @Risk, which considers inherent risk and uncertainty factors in these types of rural investment projects, under three different pasture degradation scenarios. The results indicate that the inclusion of L. diversifolia is financially profitable and substantially improves the associated risk and performance indicators. Profitability indicators increased in a range of 15‒110%, and the probability of suffering economic losses decreased from 72% to 0%. The results were directly related to the increases in animal productivity (49%) and efficiency resulting from including the legume. This work shows that L. diversifolia has significant potential to increase both animal production and profitability, which is conducive to the sustainable intensification of beef production in grazing systems.

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Kim, Gyuyeon, et Taewook Lee. « Bootstrap Value-at-Risk estimation based on CCC-GARCH models ». Journal of the Korean Data And Information Science Sociaty 29, n^o 3 (31 mai 2018) : 747–67. http://dx.doi.org/10.7465/jkdi.2018.29.3.747.

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Mistrangelo, M., C. Galassi, M. Ceccarelli, C. Monagheddu, E. Pagano, R. Rosato, P. Ivaldi et al. « START (Active Surveillance or Radical Treatment for newly diagnosed patients with a localized, low risk, prostate cancer) : an epidemiological study of the Oncology Network of Piemonte and Valle d'Aosta ». Annals of Oncology 27 (septembre 2016) : iv32. http://dx.doi.org/10.1093/annonc/mdw334.12.

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El Khatib, Dr Mounir M. « Integrating Project Risk Management and Value Engineering in Tendering Processes ». International Journal of Engineering Research 4, n^o 8 (1 août 2015) : 442–45. http://dx.doi.org/10.17950/ijer/v4s8/808.

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Kang, Minjung, Jiyeon Kim, Jongwoo Song et Seongjoo Song. « Value at Risk with Peaks over Threshold : Comparison Study of Parameter Estimation ». Korean Journal of Applied Statistics 26, n^o 3 (30 juin 2013) : 483–94. http://dx.doi.org/10.5351/kjas.2013.26.3.483.

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Romeike, Frank. « Buchbesprechung : Corporate Risk Management— Cash Flow at Risk und Value at Risk von Peter Hager ». RISKNEWS 1, n^o 3 (juin 2004) : 71–72. http://dx.doi.org/10.1002/risk.200490065.

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Echeverry-Cárdenas, Emmanuel, Carolina López-Castañeda, Juan D. Carvajal-Castro et Oscar Alexander Aguirre-Obando. « Potential geographic distribution of the tiger mosquito Aedes albopictus (Skuse, 1894) (Diptera : Culicidae) in current and future conditions for Colombia ». PLOS Neglected Tropical Diseases 15, n^o 5 (11 mai 2021) : e0008212. http://dx.doi.org/10.1371/journal.pntd.0008212.

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In Colombia, little is known on the distribution of the Asian mosquito Aedes albopictus, main vector of dengue, chikungunya, and Zika in Asia and Oceania. Therefore, this work sought to estimate its current and future potential geographic distribution under the Representative Concentration Paths (RCP) 2.6 and 8.5 emission scenarios by 2050 and 2070, using ecological niche models. For this, predictions were made in MaxEnt, employing occurrences of A. albopictus from their native area and South America and bioclimatic variables of these places. We found that, from their invasion of Colombia to the most recent years, A. albopictus is present in 47% of the country, in peri-urban (20%), rural (23%), and urban (57%) areas between 0 and 1800 m, with Antioquia and Valle del Cauca being the departments with most of the records. Our ecological niche modelling for the currently suggests that A. albopictus is distributed in 96% of the Colombian continental surface up to 3000 m (p < 0.001) putting at risk at least 48 million of people that could be infected by the arboviruses that this species transmits. Additionally, by 2050 and 2070, under RCP 2.6 scenario, its distribution could cover to nearly 90% of continental extension up to 3100 m (≈55 million of people at risk), while under RCP 8.5 scenario, it could decrease below 60% of continental extension, but expand upward to 3200 m (< 38 million of people at risk). These results suggest that, currently in Colombia, A. albopictus is found throughout the country and climate change could diminish eventually its area of distribution, but increase its altitudinal range. In Colombia, surveillance and vector control programs must focus their attention on this vector to avoid complications in the national public health setting.

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Romeike, Frank. « Buchbesprechung : Allokation von Risikokapital in Banken - Value at Risk, asymmetrische Information und rationales Herdenverhalten von Tanja Dresel ». RISKNEWS 1, n^o 5 (septembre 2004) : 76. http://dx.doi.org/10.1002/risk.200490119.

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Galassi, C., M. Ceccarelli, C. Monagheddu, E. Pagano, R. Rosato, P. Ivaldi, E. Bollito et al. « Start (active surveillance or radical treatment for newly diagnosed patients with a localized, low risk, prostate cancer) : an epidemiological study of the Oncology Network of Piemonte and Valle d’Aosta. Update 2017 ». Annals of Oncology 28 (octobre 2017) : vi20—vi21. http://dx.doi.org/10.1093/annonc/mdx423.012.

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Strnad, Petr. « Market liquidity risk and its incorporation into value at risk ». Acta Oeconomica Pragensia 17, n^o 2 (1 avril 2009) : 21–37. http://dx.doi.org/10.18267/j.aop.11.

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Burdorf, Tom, et Gary van Vuuren. « An evaluation and comparison of Value at Risk and Expected Shortfall ». Investment Management and Financial Innovations 15, n^o 4 (12 octobre 2018) : 17–34. http://dx.doi.org/10.21511/imfi.15(4).2018.02.

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As a risk measure, Value at Risk (VaR) is neither sub-additive nor coherent. These drawbacks have coerced regulatory authorities to introduce and mandate Expected Shortfall (ES) as a mainstream regulatory risk management metric. VaR is, however, still needed to estimate the tail conditional expectation (the ES): the average of losses that are greater than the VaR at a significance level These two risk measures behave quite differently during growth and recession periods in developed and emerging economies. Using equity portfolios assembled from securities of the banking and retail sectors in the UK and South Africa, historical, variance-covariance and Monte Carlo approaches are used to determine VaR (and hence ES). The results are back-tested and compared, and normality assumptions are tested. Key findings are that the results of the variance covariance and the Monte Carlo approach are more consistent in all environments in comparison to the historical outcomes regardless of the equity portfolio regarded. The industries and periods analysed influenced the accuracy of the risk measures; the different economies did not.

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Chambers, Donald R., Michael A. Kelly et Qin Lu. « Understanding the Estimation Risks of Value at Risk ». Journal of Alternative Investments 16, n^o 3 (31 décembre 2013) : 64–85. http://dx.doi.org/10.3905/jai.2013.16.3.064.

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Lupia, Tommaso, Silvia Corcione, Nour Shbaklo, Giorgia Montrucchio, Ilaria De Benedetto, Valentina Fornari, Roberta Bosio et al. « Meropenem/Vaborbactam and Cefiderocol as Combination or Monotherapy to Treat Multi-Drug Resistant Gram-Negative Infections : A Regional Cross-Sectional Survey from Piedmont Infectious Disease Unit Network (PIDUN) ». Journal of Functional Biomaterials 13, n^o 4 (3 octobre 2022) : 174. http://dx.doi.org/10.3390/jfb13040174.

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Meropenem/vaborbactam (MV) and cefiderocol were recently approved by the Food and Drug Administration and European Medicines Agency and are among the most promising antibacterial in treatment regimens against multi-drug resistant (MDR) gram-negative bacilli. A survey with close-ended questions was proposed to infectious disease (ID) and intensive care unit (ICU) physicians of Piedmont and Valle d’Aosta Region’s hospitals. The aim was to collect data about habits and prescriptions of cefiderocol and MV. Twenty-three physicians (11 ID specialists and 12 anesthesiologists) in 13 Italian hospitals took part in the survey. Both cefiderocol and MV were mostly used as target therapy after a previous treatment failure and after ID specialist consult. The most frequent MDR pathogen in hospitals was Klebsiella pneumoniae carbapenemase-producing bacteria (KPC), followed by P. aeruginosa and A. baumannii. MDRs were more frequently isolated in ICU. In conclusion, cefiderocol was used in empiric regimens when A.baumannii was suspected, while MV was more used in suspect of KPC. MV and cefiderocol can be the first option in empiric treatment for critically ill patients in settings with high risk of MDR. The treatment should then be followed by rapid de-escalation when microbiological results are available.

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Vennila, M., et C. Murthy. « Trend analysis of area, production and productivity in pigeonpea ». INTERNATIONAL JOURNAL OF AGRICULTURAL SCIENCES 17, n^o 2 (15 juin 2021) : 476–85. http://dx.doi.org/10.15740/has/ijas/17.2/476-485.

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The present study has been analysed the trend in area, production and productivity of pigeon pea and the instability by Cuddy Della Valle index. The study has been carried out based on secondary data and the data was collected for the periods from 2007-08 to 2018-19. Compound annual growth rate, co-efficient of variation and instability index was computed. The growth rate of area and production of pigeonpea in India showed and significant positive at 1 per cent and 5 per cent level, respectively and productivity showed insignificant positive growth rate. The growth rate of area and production of pigeonpea of Karnataka showed significant positive trend at 5 per cent level and productivity showed insignificant positive growth rate. The increase in production occurs due to increase in area as well as interactions of area and productivity of pigeonpea in the study period. Thus, there is a need to take up productivity enhancing measures in pigeonpea like varietal improvement, improved cultural practices, disease control measures and irrigation facilities. The instability indices for area, production and productivity for pigeonpea is positive which indicates less risk in growing pigeonpea in future.

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Sciacca, S., C. Rotondo, A. Corrado, D. Cici et F. P. Cantatore. « POS0927 CORONARY ARTERY CALCIFCATION IN SYSTEMIC SCLEROSIS : EVALUATION OF CARDIOVASCULAR RISK AND CLINICAL OUTCOME ». Annals of the Rheumatic Diseases 81, Suppl 1 (23 mai 2022) : 763.1–763. http://dx.doi.org/10.1136/annrheumdis-2022-eular.5269.

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BackgroundThe primary prevention of cardiovascular disease (CVD) is a priority element of the worldwide health care agenda. An increased risk of CVD and CV mortality has been shown in lots of studies conducted on patients affected by inflammatory and autoimmune diseases. A routine evaluation of CV risk in these patients should be encouraged and in particular cases is recommended.ObjectivesThe aim of this study is to evaluate the presence of subclinical atheromatosis, the CV risk and its performance in a cohort of patients affected by Systemic Sclerosis (SSc) from a single reference tertiary care hospital.MethodsSixty-seven patients with SSc according to the ACR/EULAR 2013 criteria were included. Traditional CV risk factors and SSc related factors were analyzed. Thoracic high resolution computed tomography (CT) was performed, using the quantification of coronary calcium for the study. Furthermore, a doppler ultrasonography of the carotids and the lower extremity arteries was conducted for the detection of subclinical atheromatosis. The CV risk has been calculated through different CV risk scales including the MESA CAC, the Italian Progetto Cuore, the Framingham score, the Score2 and the QRISK3. After conducting a 5-year follow up, CV outcome and electrocardiography abnormalities were examined.ResultsCalcium artery coronary score > 0 was reported in twenty-eight SSc patients (41,8%). Considering traditional CV risk factors, the multivariate regression analysis showed a correlation with age (OR 1.151 [95% CI 1.06–1.25], P = 0.001) and systemic arterial hypertension (OR 5 [95% CI 1.148–22.357], P = 0.032). Instead, the presence of anti-CENP-B (OR 3.47 [95% CI 1.09–11.06], P = 0.035) and late-onset disease (OR 1.062 [95% CI 1.007–1.119], P = 0.026) were identified as potential specific disease risk factors. The prevalence of ultrasonography atherosclerosis was high: peripheral artery disease (PAD) and carotid plaque were respectively 43% and 41%, and the presence of coronary calcifications was a risk factor for their detection with a OR respectively of 20.39 and 20.49 (p=0.0001). All CV risk scores considered SSc patients in a low risk, except for the QRISK3, whose values were higher in patients with coronary calcifications (18.4±12.6 vs 5.1±4.9, p=0.0001). In 5-years follow up only 1 patient died for CVD and 2 CV events occurred. Electrocardiography anomalies were found in 28.35% of patients, and in particular in 43% of patients with coronary calcifications (OR 3.321 [95% CI 1.094-10.08], P = 0.03).ConclusionSubclinical coronary atherosclerosis seems to be largely observed in SSc patients and may represent an additional risk factor for electrocardiography anomalies and subclinical atheromatosis in other anatomical districts, with no impact on CVD mortality. In our study coronary calcifications well correlated with CV risk score, especially the novel QRISK3 by classifying these patients between low and moderate CV risk. Other studies are needed to support the hypothesis that subclinical coronary atherosclerosis, occasionally detected in thoracic CT, may represent a clinical alert to establish timing and weight of diagnostic and specific treatment protocols for the CV prevention in SSc patients.References[1]Agca R, Heslinga SC, Rollefstad S, et al. EULAR recommendations for cardiovasculardisease risk management in patients with rheumatoidarthritis and otherforms of inflammatory joint disorders: 2015/2016 update. Ann RheumDis 2017; 76(1):17–28.[2]Ungprasert P, Charoenpong P. Risk of coronary artery disease in patients with systemic sclerosis: a systematic review and meta-analysis. ClinRheumatol. 2014;33(8):1099-1104[3]Sanz Pérez I, Martínez Valle F. Subclinical cardiovascular disease and Systemic Sclerosis: A comparison between risk charts, quantification of coronary calcium and carotid ultrasonography. Autoimmun Rev. 2018;17(9):900-905[4]Di Battista M, Barsotti S, Della Rossa A, Mosca M. Cardiovascular burden in systemic sclerosis: QRISK3 versus Framingham for risk estimation. ModRheumatol. 2021; roab011.Disclosure of InterestsNone declared

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