Littérature scientifique sur le sujet « Urinary exosome »
Créez une référence correcte selon les styles APA, MLA, Chicago, Harvard et plusieurs autres
Consultez les listes thématiques d’articles de revues, de livres, de thèses, de rapports de conférences et d’autres sources académiques sur le sujet « Urinary exosome ».
À côté de chaque source dans la liste de références il y a un bouton « Ajouter à la bibliographie ». Cliquez sur ce bouton, et nous générerons automatiquement la référence bibliographique pour la source choisie selon votre style de citation préféré : APA, MLA, Harvard, Vancouver, Chicago, etc.
Vous pouvez aussi télécharger le texte intégral de la publication scolaire au format pdf et consulter son résumé en ligne lorsque ces informations sont inclues dans les métadonnées.
Articles de revues sur le sujet "Urinary exosome"
Huang, Kun, Sudha Garimella, Alyssa Clay-Gilmour, Lucia Vojtech, Bridget Armstrong, Madison Bessonny et Alexis Stamatikos. « Comparison of Human Urinary Exosomes Isolated via Ultracentrifugation Alone versus Ultracentrifugation Followed by SEC Column-Purification ». Journal of Personalized Medicine 12, no 3 (24 février 2022) : 340. http://dx.doi.org/10.3390/jpm12030340.
Texte intégralAbdeen, Ahmed, Hiroko Sonoda, Ragab El-Shawarby, Saki Takahashi et Masahiro Ikeda. « Urinary excretion pattern of exosomal aquaporin-2 in rats that received gentamicin ». American Journal of Physiology-Renal Physiology 307, no 11 (1 décembre 2014) : F1227—F1237. http://dx.doi.org/10.1152/ajprenal.00140.2014.
Texte intégralLiu, Yu-Ru, et Yi-Fen Lee. « Urinary exosome and beyond ». Translational Cancer Research 5, S2 (août 2016) : S321—S324. http://dx.doi.org/10.21037/tcr.2016.07.16.
Texte intégralXiang, Xiaochao, Fulin Guan, Fenglong Jiao, Hang Li, Wanjun Zhang, Yangjun Zhang et Weijie Qin. « A new urinary exosome enrichment method by a combination of ultrafiltration and TiO2 nanoparticles ». Analytical Methods 13, no 13 (2021) : 1591–600. http://dx.doi.org/10.1039/d1ay00102g.
Texte intégralLv, Lin-Li, Yu-Han Cao, Hai-Feng Ni, Min Xu, Dan Liu, Hong Liu, Ping-Sheng Chen et Bi-Cheng Liu. « MicroRNA-29c in urinary exosome/microvesicle as a biomarker of renal fibrosis ». American Journal of Physiology-Renal Physiology 305, no 8 (15 octobre 2013) : F1220—F1227. http://dx.doi.org/10.1152/ajprenal.00148.2013.
Texte intégralGarcia-Vives, Eloi, Cristina Solé, Teresa Moliné, Marta Vidal, Irene Agraz, Josep Ordi-Ros et Josefina Cortés-Hernández. « The Urinary Exosomal miRNA Expression Profile is Predictive of Clinical Response in Lupus Nephritis ». International Journal of Molecular Sciences 21, no 4 (18 février 2020) : 1372. http://dx.doi.org/10.3390/ijms21041372.
Texte intégralLedet, Elisa M., Patrick J. Miller, Ratish Gambhira, Aryeneesh Dotiwala et A. Oliver Sartor. « Characterization of plasma-derived and urinary exosomal microRNA from metastatic CRPC patients. » Journal of Clinical Oncology 34, no 2_suppl (10 janvier 2016) : 248. http://dx.doi.org/10.1200/jco.2016.34.2_suppl.248.
Texte intégralShirley, James Forrest, Joshua Drourr, W. Taylor Edwards, Kubra Tuna, Lisa K. Ryan, Abdel Alli, Ying Tang et Sarah C. Glover. « Mast Cells in Patients with Hereditary α-Tryptasemia Promote HLA-DR Expression and a Th2-Polarizing Microenvironment in the Gastrointestinal Tract ». Journal of Immunology 202, no 1_Supplement (1 mai 2019) : 192.13. http://dx.doi.org/10.4049/jimmunol.202.supp.192.13.
Texte intégralEl Fekih, Rania, James Hurley, Vasisht Tadigotla, Areej Alghamdi, Anand Srivastava, Christine Coticchia, John Choi et al. « Discovery and Validation of a Urinary Exosome mRNA Signature for the Diagnosis of Human Kidney Transplant Rejection ». Journal of the American Society of Nephrology 32, no 4 (3 mars 2021) : 994–1004. http://dx.doi.org/10.1681/asn.2020060850.
Texte intégralCao, Yuhan, Yuanhui Shi, Yuwei Wang, Yanlang Yang, Wenjun Guo, Cuifeng Zhang, Wenjun Pei et Cong Fu. « Exosomal hsa_circ_0008925 from Urine Is Related to Chronic Renal Fibrosis ». Disease Markers 2022 (18 février 2022) : 1–10. http://dx.doi.org/10.1155/2022/1899282.
Texte intégralThèses sur le sujet "Urinary exosome"
Hiemstra, Thomas Francois. « Investigating the biology of urinary exosomes ». Thesis, University of Cambridge, 2012. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.610116.
Texte intégralBurballa, Tàrrega Carla 1988. « Discovery of putative prognostic and therapeutic miRNA in uEVs of Dent's Disease 1 patients and characterisation of cellular models of the disease ». Doctoral thesis, TDX (Tesis Doctorals en Xarxa), 2021. http://hdl.handle.net/10803/671807.
Texte intégralLa malaltia de Dent 1 (DD1) és una tubulopatia renal rara causada per mutacions en el gen CLCN5 i caracteritzada per proteinuria de baix pes molecular, hipercalciuria, nefrocalcinosi i/o litiasis renals així com progrés a insuficiència renal. Els mecanismes que causen la pèrdua de funció de ClC-5 i el defecte en l’endocitosi en el túbul proximal (entre d’altres fenotips de DD1) no es coneixen. En aquesta Tesi hem desenvolupat tres aproximacions per identificar vies alterades per mutacions en ClC-5. (1) hem fet una enquesta europea per analitzar la prevalença i les característiques clíniques de DD1, (2) hem estudiat l’expressió de miRNA en vesícules exosome-like urinàries (uEVs) per entendre els mecanismes fisiopatològics de la malaltia i (3) hem caracteritzat un model cel·lular de DD1. L’enquesta europea mostrà que DD1 té una presentació variable. El nostre estudi de miRNA en uEVs va permetre identificar nous mecanismes fisiopatològics que poden ser potencials biomarcadors diagnòstics i pronòstics de DD1. Finalment, el nostre model cel·lular amb diferents mutacions provà representar un prototip vàlid per investigacions addicionals del mecanismes desregulats.
CORBETTA, SAMUELE. « Proteomica degli exosomi urinari per la ricerca di biomarcatori nella nefropatia diabetica e nelle tubulopatie ereditarie ». Doctoral thesis, Università degli Studi di Milano-Bicocca, 2015. http://hdl.handle.net/10281/76004.
Texte intégralMiao, Yuxuan. « Mechanisms of Bacterial Expulsion as a Cell Autonomous Defense Strategy In the Bladder Epithelium ». Diss., 2015. http://hdl.handle.net/10161/9862.
Texte intégralDue to its close proximity to the gastrointestinal tract, the human urinary tract is
subjected to constant barrage by gut-associated bacteria. However, for the most part, this tract has resisted infection by various microbes. The impregnability of the urinary tract to microbial colonization is attributable to the ability of the bladder to promptly sense and mount robust responses to microbial challenge. A powerful mechanism for the elimination of invading bacteria was recently described in bladder epithelial cells, involving non-lytic ejection of intracellular bacteria back into the extracellular milieu. In spite of the effectiveness of this defense strategy, much of the underlying mechanisms surrounding how this powerful cellular defense activity detects intracellular UPEC and shuttles them from their intracellular location to the plasma membrane of BECs to be exported remains largely a mystery.
Here, we describe uropathogenic E.coli (UPEC) expelled from infected bladder
epithelium cells (BECs) within membrane-bound vesicles as a distinct cellular defense
response. Examination of the intracellular UPEC revealed that intracellular bacteria were
initially processed via autophagy, the conventional degradative pathway, then delivered
into multivesicular bodies (MVBs) and encapsulated in nascent intraluminal vesicle membrane. We further show the bacterial expulsion is triggered when intracellular UPEC follow the natural degradative trafficking pathway and reach lysosomes and attempt to neutralize its pH to avoid degradation. This pathogen-mediated activity is detected by mucolipin TRP channel 3 (TRPML3), a transient receptor potential cation channel localized on lysosomes, which spontaneously initiates lysosome exocytosis resulting in expulsion of exosome-encased bacteria. These studies reveal a cellular default system for lysosome homeostasis and also, how it is coopted by the autonomous defense program to clear recalcitrant pathogens.
Dissertation
Lai, Yue Fan, et 賴岳汎. « Searching Potential Protein Biomarkers of Bladder Cancer from Urinary Exosomes ». Thesis, 2011. http://ndltd.ncl.edu.tw/handle/58768233351293356294.
Texte intégral長庚大學
生物醫學研究所
99
Bladder cancer mortality increases annually in Taiwan. The main detection tool for bladder cancer is cystoscopy. However, this method is an invasive and costly procedure. Urine is stored in bladder for hours and can be collected non-invasively. Therefore, urine can be a good material for discovery of bladder cancer biomarkers. Multivesicular body derived exosomes present in saliva, plasma, and urine. Previous studies pointed out that exosomes correlate with diseases, and can be a material for biomarker searching. In this work, we compared the proteomic profiles of urinary exosomes between controls and bladder cancer patients using isotopic dimethyl labelling and two-dimensional LC/MS/MS. The differentially-expressed exosomal proteins will be potential non-invasive biomarkers for detection of bladder cancer. Exosomes extracted from 9 hernia and 9 bladder cancer patients were pooled as a control and a bladder cancer samples, respectively. After digestion of exosomal proteins, peptides of hernia and bladder cancer samples were labelled with light and heavy dimethylation reagents, respectively. The labelled peptides were analyzed by on-line SCX/RP LC/MS/MS. The quantification of proteins were performed by MaxQuant software. We further used the dimethylation platform to compare the exosome proteins expressions of 9 hernia and 9 bladder cancer individuals without pooling samples. We have indentified total 3873 exosomal proteins in two comparisons, and 107 proteins show higher different concentration levels between bladder cancer and hernia patients. 29 of 107 proteins in urinary exosomes could directly quantified by multiple-reaction-monitoring (MRM)-MS. MRM-MS validated 29 proteins expression levels between 5 hernia and 5 bladder cancer patients’ exosomes, and most results were consistent with that we have seen in discovery phase. Then we validated more clinical sample. We quantified 29 proteins expression levels in 12 hernia, 28 bladder cancer, 5 hematuria and 3 urinary tract infection patients’ exosomes. 22 of 29 proteins had significant differentially expressed level between hernia and bladder cancer patient, and higher expressed level of 3 proteins in bladder cancer patients were not due to hematuria or urinary tract infection. In this work, we implemented two comparisons to searching differentially-expressed exosomal proteins, and we validated these proteins by MRM-MS. The validation results are consistent with prediction. In the future, we will increase the sample number to raise the reliability of these potential bladder cancer biomarkers.
Lin, Shih-Yi, et 林詩怡. « Investigate the proteomics of urinary exosomes for biomarkers of urothelial carcinoma ». Thesis, 2016. http://ndltd.ncl.edu.tw/handle/59sj6j.
Texte intégral中國醫藥大學
臨床醫學研究所博士班
105
Purpose: Studies have focused on establishing noninvasive, rapid methods for discovering urothelial carcinoma (UC) biomarkers. The urinary exosome proteome is believed to directly reflect the proteome of UC, providing a suitable investigation resource. Increasingly applied matrix-assisted laser desorption/ionization time-of-flight (MALDI-TOF) spectrometry facilitates reliable clinical diagnosis of bacteria. MALDI-TOF spectrometry, a rapid analytical platform, has not been used for urinary exosome analysis. Therefore, we used it for determining UC biomarkers. Experimental Design: From 2012 to 2015, we enrolled 129 consecutive patients with UC and 62 participants without UC. Exosomes from their urine were isolated, and the protein extracts of these exosomes were analyzed through MALDI-TOF spectrometry. Moreover, immunohistochemical (IHC) analysis of another 122 UC and 26 non-UC tissues was conducted to verify the discovered biomarkers. Results: Two peaks at m/z 5593 (fragmented peptide of alpha-1-antitrypsin; sensitivity, 50.4%; specificity, 96.9%) and m/z 5947 (fragmented peptide of histone H2B1K sensitivity, 62.0%; specificity, 92.3%) were identified as UC diagnosis exosome biomarkers. UC patients with detectable histone H2B1K showed 2.29- and 3.11-fold increased risks of recurrence and progression, respectively, compared with those with nondetectable histone H2B1K. Verification results of IHC staining revealed significantly higher expression of alpha 1-antitrypsin (p = 0.038) and H2B1K (p = 0.005) in UC tissues than in normal tissues. The expression of alpha 1-antitrypsin and H2B1K in UC tissues was significantly correlated with UC grades (p < 0.05). Conclusion: Urinary exosome proteins alpha 1-antitrypsin and histone H2B1K, which are identified through MALDI-TOF analysis, could facilitate rapid diagnosis and prognosis of UC.
Chapitres de livres sur le sujet "Urinary exosome"
Salvi, Samanta, Erika Bandini et Francesco Fabbri. « Urinary Exosomes in Prostate Cancer ». Dans Urinary Biomarkers, 115–20. New York, NY : Springer US, 2021. http://dx.doi.org/10.1007/978-1-0716-1354-2_10.
Texte intégralAlvarez-Llamas, Gloria, et Irene Zubiri. « Proteome of Human Urinary Exosomes in Diabetic Nephropathy ». Dans Biomarkers in Kidney Disease, 347–67. Dordrecht : Springer Netherlands, 2016. http://dx.doi.org/10.1007/978-94-007-7699-9_22.
Texte intégralAlvarez-Llamas, Gloria, et Irene Zubiri. « Proteome of Human Urinary Exosomes in Diabetic Nephropathy ». Dans Biomarkers in Kidney Disease, 1–21. Dordrecht : Springer Netherlands, 2015. http://dx.doi.org/10.1007/978-94-007-7743-9_22-1.
Texte intégralAbdeen, Ahmed, Hiroko Sonoda, Ayae Tanaka et Masahiro Ikeda. « Urinary Exosomes as a Possible Source of Kidney Disease Biomarkers ». Dans Role of Exosomes in Biological Communication Systems, 221–44. Singapore : Springer Singapore, 2020. http://dx.doi.org/10.1007/978-981-15-6599-1_10.
Texte intégralPitto, Marina, Samuele Corbetta et Francesca Raimondo. « Preparation of Urinary Exosomes : Methodological Issues for Clinical Proteomics ». Dans Methods in Molecular Biology, 43–53. New York, NY : Springer New York, 2014. http://dx.doi.org/10.1007/978-1-4939-1872-0_3.
Texte intégralBarigazzi, Elisa, Lucia Santorelli, W. Morello, F. Raimondo, B. Crapella, L. Ghio, C. Tamburello, G. Montini et M. Pitto. « New Insight into Idiopathic Nephrotic Syndrome : Strategy Based on Urinary Exosomes ». Dans Toxic Chemical and Biological Agents, 217–18. Dordrecht : Springer Netherlands, 2020. http://dx.doi.org/10.1007/978-94-024-2041-8_13.
Texte intégralSantorelli, Lucia, Elisa Barigazzi, M. Pitto et F. Raimondo. « Investigation of the N-Glycoproteome in the Urinary Exosomes : Technical Challenges ». Dans Toxic Chemical and Biological Agents, 257–58. Dordrecht : Springer Netherlands, 2020. http://dx.doi.org/10.1007/978-94-024-2041-8_26.
Texte intégralConde-Vancells, Javier, et Juan M. Falcon-Perez. « Isolation of Urinary Exosomes from Animal Models to Unravel Noninvasive Disease Biomarkers ». Dans Liver Proteomics, 321–40. Totowa, NJ : Humana Press, 2012. http://dx.doi.org/10.1007/978-1-61779-959-4_21.
Texte intégralDiStefano, Johanna K., Rupesh Kanchi Ravi et Mahdieh Khosroheidari. « Urinary Exosomes as Potential Source for Identification of Biomarkers for Kidney Damage : Comparing Methodologies ». Dans Biomarkers in Disease : Methods, Discoveries and Applications, 939–54. Dordrecht : Springer Netherlands, 2015. http://dx.doi.org/10.1007/978-94-007-7696-8_47.
Texte intégralAlvarez, M. Lucrecia. « Isolation of Urinary Exosomes for RNA Biomarker Discovery Using a Simple, Fast, and Highly Scalable Method ». Dans RNA Mapping, 145–70. New York, NY : Springer New York, 2014. http://dx.doi.org/10.1007/978-1-4939-1062-5_13.
Texte intégralActes de conférences sur le sujet "Urinary exosome"
Blondal, Thorarinn, Anne I. Rasmussen, Anni R. Thomsen, Michael Borre, Jacob Fredsøe, Ditte Andreasen, Torben Falck Ørntoft, Karina D. Sørensen et Peter Mouritzen. « Abstract 1943 : A microRNA signature in urinary exosomes for diagnosis of prostate cancer ». Dans Proceedings : AACR 107th Annual Meeting 2016 ; April 16-20, 2016 ; New Orleans, LA. American Association for Cancer Research, 2016. http://dx.doi.org/10.1158/1538-7445.am2016-1943.
Texte intégralMouritzen, Peter, Jacob Christian Fredsøe, Thorarinn Blondal, Anne Karin Rasmussen, Michael Borre, Christa Haldrup, Ditte Andreasen, Niels Tolstrup, Torben Falck Ørntoft et Karina Dalsgaard Sørensen. « Abstract B40 : A two-microRNA signature in urinary exosomes for diagnosis of prostate cancer ». Dans Abstracts : AACR Special Conference on Noncoding RNAs and Cancer : Mechanisms to Medicines ; December 4-7, 2015 ; Boston, MA. American Association for Cancer Research, 2016. http://dx.doi.org/10.1158/1538-7445.nonrna15-b40.
Texte intégralBerner, K., M. Hirschfeld, G. Rücker, D. Weiß, A. Ritter, M. Jäger, I. Juhasz-Böss et T. Erbes. « Urinary exosomal microRNAs as potential non-invasive biomarkers in breast cancer detection ». Dans 40. Jahrestagung der Deutschen Gesellschaft für Senologie e.V. © Georg Thieme Verlag KG, 2020. http://dx.doi.org/10.1055/s-0040-1710603.
Texte intégralBerner, K., M. Hirschfeld, G. Rücker, D. Weiß, A. Ritter, I. Juhasz-Böss et T. Erbes. « Urinary exosomal microRNAs as potential non-invasive biomarkers in breast cancer detection ». Dans Kongressabstracts zur Tagung 2020 der Deutschen Gesellschaft für Gynäkologie und Geburtshilfe (DGGG). © 2020. Thieme. All rights reserved., 2020. http://dx.doi.org/10.1055/s-0040-1717838.
Texte intégralBaumgart, Sophie, Joana Heinzelmann, Michael Stoeckle, Marie Stampe Ostenfeld et Kerstin Junker. « Abstract 5182 : Characterization of miRNA expression pattern fromin-vitroobtained exosomes of different urinary bladder cancer cell lines ». Dans Proceedings : AACR 106th Annual Meeting 2015 ; April 18-22, 2015 ; Philadelphia, PA. American Association for Cancer Research, 2015. http://dx.doi.org/10.1158/1538-7445.am2015-5182.
Texte intégralWilson, Brittany, Rebekah Betar, Alexander Martin, Zackaria Niazi, Michael Boyer, Lori Winter, Victor Babich, Francesca Di Sole et Elitsa Ananieva. « Abstract 2377 : microRNA expression profile in urinary exosomes is dependent on non-invasive lymphoma induction in mice ». Dans Proceedings : AACR Annual Meeting 2021 ; April 10-15, 2021 and May 17-21, 2021 ; Philadelphia, PA. American Association for Cancer Research, 2021. http://dx.doi.org/10.1158/1538-7445.am2021-2377.
Texte intégralBerrondo, Claudia, Jonathan Flax, Aisha Siebert, Victor Kucherov, Alex Rosenberg, Christopher Fucile et Carla Beckham. « Abstract B31 : Bladder cancer patient urinary exosomes and tumors contain long noncoding RNA that may serve as therapeutic targets and biomarkers ». Dans Abstracts : AACR Special Conference on Noncoding RNAs and Cancer : Mechanisms to Medicines ; December 4-7, 2015 ; Boston, MA. American Association for Cancer Research, 2016. http://dx.doi.org/10.1158/1538-7445.nonrna15-b31.
Texte intégralSolé-Marcé, Cristina, Eloi Garcia-Vives, Irene Agraz, Josep Ordi-Ros et Josefina Cortés-Hernández. « THU0236 URINARY EXOSOMAL MIR-31, MIR-107 AND MIR-135B-5P FROM TUBULAR RENAL CELLS AS RESPONDER BIOMARKER IN LUPUS NEPHRITIS ». Dans Annual European Congress of Rheumatology, EULAR 2019, Madrid, 12–15 June 2019. BMJ Publishing Group Ltd and European League Against Rheumatism, 2019. http://dx.doi.org/10.1136/annrheumdis-2019-eular.5346.
Texte intégral