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Littérature scientifique sur le sujet « Urinary bladder neoplasia »

Auteur : Grafiati
Publié le 9 mars 2023
Mis à jour le 10 mars 2023

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Articles de revues sur le sujet "Urinary bladder neoplasia"

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Shah, Anita, Manglesh Srivastava, Ashok Samdurkar et Ghanshyam Sigdel. « Spectrum of Lesions in Urinary Bladder- A Histopathological Study ». Journal of Universal College of Medical Sciences 6, no 2 (3 décembre 2018) : 24–27. http://dx.doi.org/10.3126/jucms.v6i2.22473.

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Introduction: The lesions of urinary bladder both non-neoplastic and neoplastic pose a common source of both morbidity and mortality. An accurate diagnosis of these lesions requires cystoscopy which allows a direct visualization of the bladder mucosa and biopsies of suspected lesions. Urinary bladder cancer is sixth most common cancer worldwide and represents a heterogeneous group of neoplasms. The current study aimed to study the different bladder lesions and its clinical features to detect it in early stage and as a mainstay option in the diagnosis and follow up. Materials and methods: This was a retrospective analysis of biopsies of urinary bladder submitted to the department of pathology over a period of 12 months. The study was approved by the institutional review board of the Universal College of Medical Sciences (UCMS-TH). All the urinary bladder biopsies received in the department were included in the study whereas autolysis of specimen and inadequate biopsies were excluded. Results: Among the 36 cases of urinary bladder lesions, the majority (35.36%) were in age group 61-70 years (22.33%). The patients had combination of lower urinary tract symptoms, the commonest being hematuria. 30.55% had non-neoplastic lesions and 69.55% had neoplastic lesion. Among non- neoplastic cases, 5.55% had chronic granulomatous inflammation. Most common neoplastic lesions was infiltrating urothelial carcinoma (n=6) followed by non- invasive urothelial neoplasia (n=5). Conclusion: A variety of lesions occur in urinary bladder and is commonly encountered by pathologist. Hematuria was commonest symptom and the clinicians investigated these patients further, which led to discovery of the urothelial tumors. Identification of these patients has an important impact on prognosis as well as on therapeutic approach.
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Griffin, Maureen, William Culp et Robert Rebhun. « Lower Urinary Tract Neoplasia ». Veterinary Sciences 5, no 4 (27 novembre 2018) : 96. http://dx.doi.org/10.3390/vetsci5040096.

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Lower urinary tract neoplasia in companion animals is a debilitating and often life-threatening disease. Tumors of the bladder, urethra, and prostate often occur independently, although extension of these tumors into adjacent regions of the lower urinary tract is documented frequently. The most common lower urinary tract tumor in dogs and cats is transitional cell carcinoma (TCC). In both dogs and cats, TCC affecting the urinary bladder is generally considered to be highly aggressive with both local and metastatic disease potential, and this disease poses unique treatment challenges. Whereas much literature exists regarding the TCC disease process, treatment options, and prognosis in dogs, relatively few studies on feline TCC have been published due to the lower incidence of TCC in this species. Prostate tumors, most commonly adenocarcinomas, occur less commonly in dogs and cats but serve an important role as a comparative model for prostate neoplasia in humans. This article serves as a review of the current information regarding canine and feline lower urinary tract neoplasia as well as the relevance of these diseases with respect to their human counterparts.
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Pini, Giacomo Maria, Silvia Uccella, Matteo Corinti, Maurizio Colecchia, Giuseppe Pelosi et Carlo Patriarca. « Primary MiNEN of the urinary bladder : an hitherto undescribed entity composed of large cell neuroendocrine carcinoma and adenocarcinoma with a distinct clinical behavior ». Virchows Archiv 479, no 1 (17 janvier 2021) : 69–78. http://dx.doi.org/10.1007/s00428-021-03023-7.

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AbstractNeuroendocrine carcinomas (NECs) of the urinary bladder are very rare and can be observed in the context of mixed neuroendocrine/non-neuroendocrine neoplasms (MiNENs), most frequently in association with urothelial carcinoma. Small cell NECs are far more common than large cell NECs (LCNECs), which are exceedingly rare. We describe a primary MiNEN of the urinary bladder, composed of a LCNEC and of an adenocarcinoma, in which the neuroendocrine component reached complete pathological regression after neoadjuvant M-VAC chemotherapy, whereas the non-neuroendocrine component of the tumor progressed to metastatic disease. Compared to mixed neuroendocrine/non-neuroendocrine neoplasms described in the literature until now, this appears to be a unique case that expands the spectrum of neuroendocrine neoplasia of the urinary bladder.
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HARTVEIT, FLORA, B. O. MAEHLE et S. THUNOLD. « Koilocytosis in Neoplasia of the Urinary Bladder ». British Journal of Urology 69, no 1 (janvier 1992) : 46–48. http://dx.doi.org/10.1111/j.1464-410x.1992.tb15457.x.

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Ferrante, Bruno, Carina Outi Baroni, Caterina Muramoto, Igor Almeida Dos Santos, Hock Gan Heng et Ana Carolina Brandão de Campos Fonseca Pinto. « Post Mortem Ultrasound and Computed Tomography Findings of an Extraluminal Urinary Bladder Leiomyoma in a Dog ». Acta Scientiae Veterinariae 45 (27 juin 2017) : 4. http://dx.doi.org/10.22456/1679-9216.86231.

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Background: Neoplasia of the urinary bladder is common in dogs, accounting approximately 0.5 to 1.0 percent of all neoplasms. Most of the neoplasia of the urinary bladder is epithelial in origin and only 10% of urinary bladder neoplasms in dogs are from mesenchymal origin, of which the most frequent types are leiomyoma / leiomyosarcoma, and hemangioma / hemangiosarcoma. Virtual autopsy refers to the postmortem use of radiology, ultrasound and cross-sectional imaging prior to conventional necropsy. This paper reports the detection of a rare extra-luminal urinary bladder mass diagnosed as leiomyoma with a virtual autopsy techniques.Case: A 16-year-old male Schnauzer had previous history of seizure and no complains related to the urinary system. The animal was treated symptomatically to the neurological signs and responded to medical treatment. Nine weeks later from the first visit to the hospital the dog was found dead at home. Then postmortem ultrasound and computed tomography of the abdomen were performed. Postmortem ultrasound revealed a homogenously hypoechoic, rounded and slightly irregularly marginated mass located externally but adjacent to the left cranial wall of the urinary bladder and appears to extend from its serosal margins. Postmortem computed tomography was performed after postmortem ultrasound. A pedunculated homogenous soft tissue attenuating mass was located at the left lateral aspect of the urinary bladder and extended cranially. It had a stalk that connected to the left lateral wall of the urinary bladder. A partial necropsy of the abdomen was done just to examine the mass. A round extraluminal, pedunculated mass was observed at the left lateral aspect of the urinary bladder wall. It was pale pink on the outside and white inside, with a soft to firm consistency. The lumen and mucosal surface of the urinary bladder was smooth and regular. The histology of the mass revealed a densely cellular neoplastic proliferation, expansive, composed of spindle-shaped cells with moderate to large eosinophilic cytoplasm, sometimes wavy and with indistinct edges. The nuclei were large, oval to flattened, with dense chromatin and inconspicuous nucleoli. Anisocytosis and anisokariosis were discrete and no mitotic figures were observed. The arrangement consisted of dense, irregular and multidirectional bundles and the stroma was scarce. The mass was histologically confirmed as leiomyoma.Discussion: In this case, we performed postmortem ultrasound and computed tomography as part of a virtual necropsy study and in both modalities the urinary bladder mass was able to be identified, followed by a partial necropsy to further investigate the nature of the mass and to collect a sample to obtain the histological diagnosis. A few of the disadvantages of the postmortem ultrasound and computed tomography specially in this case were the lack of color Doppler investigation on ultrasound and the lack of evaluation of the patter of contrast enhancement on computed tomography. These techniques could have added important information related to the vascularity characteristics of the mass in a live patient. This is the first case report in veterinary medicine that describes an extra-luminal pedunculated urinary bladder leiomyoma in a canine patient, and it is emphasized the approach by postmortem ultrasound, postmortem computed tomography and conventional necropsy findings to reach the definitive diagnosis.
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Damjanov, Ivan, et Mileta Golubovic. « Histopathology of urinary bladder carcinoma : Less common variants ». Srpski arhiv za celokupno lekarstvo 139, no 9-10 (2011) : 693–99. http://dx.doi.org/10.2298/sarh1110693d.

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Bladder cancer is a common form of neoplasia which most often presents histologically as urothelial (transitional cell) carcinoma. In this article we review recent publications dealing with the less common variants of urothelial carcinoma such as tumours that show unusual forms of differentiation or the well know squamous, glandular, or sarcomatoid differentiation. Urothelial tumours may also show several distinct growth variants characterized by a nested, micropapillary, lymphoepithelioma-like, or plasmacytoid and giant cell growth pattern. The clinical course of bladder cancer varies depending on the histological type of neoplasia, grade and stage of the tumour. High-grade muscle-invasive urothelial cancers and tumours showing variant microscopic morphology have in general high mortality and poor prognosis.
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Jones, Emily, John Alawneh, Mary Thompson et Rachel Allavena. « Association between case signalment and disease diagnosis in urinary bladder disease in Australian cats and dogs ». Journal of Veterinary Diagnostic Investigation 33, no 3 (2 avril 2021) : 498–505. http://dx.doi.org/10.1177/10406387211004008.

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Urinary bladder diseases are common in dogs and cats; however, there is little published work on urinary bladder disease in Australian pets. We identified pathology records of Australian dogs and cats with urinary bladder tissue submitted to the University of Queensland Veterinary Laboratory Service during 1994–2016 ( n = 320). We described the proportion of bladder diseases in dogs and cats, and applied the less-commonly used logistic regression procedure to quantify associations between signalment variables and disease diagnosis that were evident using descriptive statistics alone. After preliminary analysis, both species were combined because of similar results. Spayed/castrated animals were 74% less likely to be diagnosed with cystitis compared with intact animals. Animals 4–11 y old were also at lower risk of being diagnosed with cystitis compared with younger or older animals. Male animals were at increased risk of neoplasia compared to females, which contrasts with reports from North America and Europe. There was increased risk for developing neoplasia with progressive age, with up to 20 times higher odds in the > 11-y age group. Logistic regression modeling provided unique insight into proportionate morbidity of urinary bladder diseases in Australian dogs and cats.
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Dalal, Niti, Sonia Chhabra, Gourav Tehri, Hemant Kamal, Monika Gupta et Rajeev Sen. « Evaluation of bladder washings cytology in diagnosis of neoplasms of urinary bladder ». IP Archives of Cytology and Histopathology Research 7, no 1 (15 mars 2022) : 20–25. http://dx.doi.org/10.18231/j.achr.2022.005.

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Urinary cytology functions as the primary screening and surveillance modality for the detection of urothelial neoplasia. To determine the significance of urinary bladder wash cytology in predicting various grades of urothelial carcinoma of urinary bladder along with their histological confirmation. The prospective study was conducted in Department of Pathology, PGIMS, Rohtak. A total of thirty-one urinary bladder washing samples (processed by Conventional method, Cytospin and Liquid based cytology) were taken prior to biopsy from clinically suspected patients of urinary bladder neoplasm. The cytological examination of bladder washings was reported according to The Paris System for Reporting Urinary Cytology and Bladder biopsies were reported according to WHO/ISUP grading of Urothelial Tumors 2004. All the data were statistically analysed using SPSS version 20.0 software. There was no significant difference in diagnostic accuracy among three techniques of processing bladder washings. Correlations of cytological diagnosis on bladder wash specimens with histopathological diagnosis were statistically significant and shared good agreement. A negative bladder wash cytology coupled with a negative cystoscopy is quite specific. A diagnosis of positive or suspicious bladder wash should be thoroughly investigated and followed closely. The Paris System is easy, reproducible, consistent ad has good histopathological correlation.
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da Luz Ferro, Sayonara, Ewerton Cardoso, Fernanda Jönck, Marta Cristina Thomas Heckler, Bruna Warmlin et Mateus Rychescki. « Urinary bladder rupture due to hemangioma in a dog – case report ». Clínica Veterinária XXIII, no 132 (1 janvier 2018) : 56–64. http://dx.doi.org/10.46958/rcv.2018.xxiii.n.132.p.56-64.

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Hemangioma is a benign, noninvasive and non-metastatic neoplasm originating from endothelial cells of the blood vessels. The involvement of the urinary vesicle with neoplasias occurs in less than 0.5% of dogs. The main clinical signs are hematuria, dysuria, pollakiuria, incontinence and urinary obstruction. The diagnosis is based on imaging tests and is confirmed by histopathological examination. The treatment of choice is surgical resection with safety margins. This paper reports the case of a twelve-year-old Poodle with a history of abdominal pain, which was attended at the Florianópolis Veterinary Hospital. Abdominal ultrasound showed the presence of free fluid. During exploratory laparotomy, the urinary vesicle was observed to be ruptured, presenting a thickened wall and small areas of necrosis. A sample was sent for histopathological analysis and the diagnosis was of benign vascular neoplasia compatible with hemangioma.
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Silver, Susan A., et Jonathan I. Epstein. « Adenocarcinoma of the Colon Simulating Primary Urinary Bladder Neoplasia ». American Journal of Surgical Pathology 17, no 2 (février 1993) : 171–78. http://dx.doi.org/10.1097/00000478-199302000-00008.

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Thèses sur le sujet "Urinary bladder neoplasia"

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Bryant, Philip. « Malignant potential of the papillomavirus and its role in the pathogenesis of human urinary bladder neoplasia ». Thesis, Open University, 1992. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.303367.

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SPEDIACCI, CARLOTTA. « INNOVATIVE IMAGING OF URINARY SYSTEM IN CANINE AND FELINE PATIENTS ». Doctoral thesis, Università degli Studi di Milano, 2023. https://hdl.handle.net/2434/951201.

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Diseases of the urinary system are regularly encountered in daily veterinary practice. The development of increasingly efficient diagnostic tools is crucial to meet the high-quality requirements of contemporary professional standards. This project had many purposes, aiming to describe pioneering methods, protocols and diagnosis related to imaging of ureters and urinary bladder, chosen as they represent daily diagnostic challenges in daily routine practice. This project consisted of three papers: the first paper is a prospective pilot project concerning quantitative CEUS exam applied to distinguish neoplastic and non-neoplastic lesions of the urinary bladder in small animals; the second paper is a multicentric retrospective observational project describing the CT appearance of a novel CVC congenital malformation; the third paper is a retrospective study conducted on canine healthy patients, aimed at assessing the visibility of the ureters on high field MR on T1 and T2 sequences avoiding the use of paramagnetic contrast agents. The results of this project allowed to obtain objectifiable parameters for the distinction of neoplastic and non-neoplastic lesions of urinary bladder using quantitative CEUS; we also described the CT appearance of the transcaval ureter, a malfomaration of the CVC never described in veterinary medicine; finally, we described the feasibility of evaluation of normal ureters through high-field MR on T2-weighted sequences, in healthy canine patients. In conclusion, this project allowed to describe new diseases that could affect urinary tract function and contributes to the development of new methods and protocols with the potential to reduce the invasiveness of certain diagnostic procedures related to the urinary tract.
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Guimarães, Pedro Edson Moreira. « Estudo molecular de genes envolvidos com adesão celular em câncer de bexiga ». Universidade de São Paulo, 2007. http://www.teses.usp.br/teses/disponiveis/5/5153/tde-04062008-104314/.

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Introdução: O câncer de bexiga é a quinta neoplasia mais comumente diagnosticada no Ocidente, acometendo cerca de 336.000 novos indivíduos anualmente e levando a morte 132.000 pacientes em todo o mundo. No Brasil, a incidência de tumores vesicais para o ano de 1999 foi de 7.550, representando 2,8% do total de casos novos de câncer diagnosticados em ambos os sexos. Um dos grandes desafios terapêuticos para o câncer de bexiga é a identificação dos pacientes que inicialmente apresentam carcinoma papilífero de baixo grau, mas que irão recorrer ou progredir. Métodos: Neste estudo retrospectivo 64 pacientes foram avaliados por imunohistoquímica para a análise da expressão de E-caderina e β-catenina. As marcações foram classificadas como focal ou difusa e categorizadas em negativo, fraco, moderado e forte. Os resultados foram correlacionados com grau histológico, estadiamento clínico, sobrevida livre de progressão e sobrevida livre de recidiva. O polimorfismo de ninjurin 1 foi genotipado por PCR-RFLP em 66 pacientes e 108 controles. Os genótipos foram correlacionados com grau histológico, estadiamento clínico, sobrevida livre de progressão e sobrevida livre de recidiva. Resultados: Em nossa casuística padrões mais intensos de imuno-expressão de Ecaderina foram estatisticamente associados a estádios clínicos mais avançados para carcinomas uroteliais da bexiga (p=0,005), além de menores tempos de recidiva (0,025) e progressão (0,049). O padrão de marcação difuso foi associado de forma estatisticamente significativa a estádios clínicos mais avançados (p=0,010). Não foram encontradas associações significativas entre os padrões de imuno-expressão de β-catenina com grau histológico, estádio tumoral, recidiva ou progressão dos carcinomas uroteliais da bexiga. O alelo C do polimorfismo D110A de ninjurin 1 foi associado de forma estatisticamente significativa, em nossa amostra, com o aumento do grau histológico (p=0,041). Pacientes portadores do alelo C de ninjurin 1 apresentaram menores períodos para progressão tumoral quando comparados aos homozigotos AA (p=0,010). Conclusão: Nossos resultados sugerem que a expressão de E-caderina está envolvida nos processos tumorigênese do carcinoma urotelial de bexiga e que o polimorfismo D110A de ninjurin 1 pode participar da modulação desta patologia.
Introduction: Bladder cancer is the fifth neoplasm in Western countries, whose occurrence is 336,000 new cases annually, and also being responsible for 132,000 deaths in the worldwide. The incidence of bladder tumors in Brazil were 7,550 cases in 1999, representing 2,8% of overall diagnosed cancer in both gender. One of the main therapeutic challenges is identify which patients that present low grades neoplasms will present recurrence and/or progression. Methods: Sixty four patients were evaluated for E-cadherin e β-catenin immunoexpression in a retrospective study. The staining patterns were classified as focal or difuse and categorized as negative, weak, moderate or strong. Results were correlated with tumor grade, clinical stage, progression and recurrence free survival. Ninjurin 1 polymorphism was evaluated by PCR-RFLP in 66 patients and 108 controls. Genotypes were correlated with tumor grade, clinical stage, progression and recurrence free survival. Results: E-cadherin moderate and strong staining patterns were significantly associated with high clinical stages of urothelial carcinoma of bladder (p=0.005), and short recurrence (p=0.025) and progression (p=0.049). Difuse staining pattern were significantly associated with high clinical stages (p=0.010). Neither histological grade, clinical stages, recurrence and progression free survival were associated with β-catenin staining patters in our samples of urothelial carcinoma of bladder. The allele C of D110A ninjurin 1 polymorphism was significantly associated with high grade tumors (p=0.041). C carries patients compared with AA homozygous presented short disease progression (p=0.010). Conclusion: Our results suggest that E-cadherin expression is involved in urothelial carcinoma of bladder tumorigenesis and that D110A ninjurin 1 polymorphism may contribute to modulate this pathology.
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Sanyal, Somali. « Effect of genetic polymorphisms on urinary bladder neoplasms / ». Stockholm, 2007. http://diss.kib.ki.se/2007/978-91-7357-081-7/.

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Juveniz, João Alexandre Queiroz. « A importância da biópsia de congelação como método complementar à ressecção endoscópica em câncer de bexiga : um estudo prospectivo randomizado ». Universidade de São Paulo, 2016. http://www.teses.usp.br/teses/disponiveis/5/5153/tde-18012017-153659/.

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Introdução: Apesar de recentes inovações e aprimoramentos no tratamento do Câncer de Bexiga (CaB) não músculo invasivo, o índice de progressão e recorrência continuam altos possivelmente devido a tumores residuais ou não evidenciados na ressecção transuretral de bexiga (RTU), o que profundamente afeta o prognóstico desta doença e evidencia a importância da qualidade desse procedimento padrão não só para o diagnóstico, mas também para o estadiamento e tratamento do tumor de bexiga. A presença de muscular própria no espécime é essencial para conduzir o tratamento, embora esta esteja presente apenas em cerca de 36-51% dos casos. Na sua ausência muitas vezes torna-se necessário um novo procedimento, vindo com isso a morbidade e os gastos de uma nova cirurgia. Dessa forma várias técnicas têm sido propostas com o intuito de melhorar a acurácia da RTUb, o que pode reduzir as ressecções incompletas e o subestadiamento. Objetivo: Avaliar a importância da biópsia de congelação do leito da lesão ressecada no que diz respeito ao estadiamento inicial e controle local da doença. Materiais e Métodos: Estudo prospectivo e randomizado dos pacientes com tumor de bexiga sem tratamento prévio que foram submetidos à RTUb no período de 09/2011 a 08/2013 em uma única instituição (Instituto do Câncer do Estado de São Paulo - ICESP). Esses pacientes foram submetidos à RTUb convencional, conforme o Guideline Europeu (EAU, 2011). No grupo 1, foi realizada biópsia de congelação do leito da lesão após a RTU, onde o cirurgião julgou esta ser possivelmente invasiva, aguardando análise do patologista quanto a presença de muscular própria, se caso esta não estivesse representada, era feita nova biópsia até sua representatividade. O grupo 2 são os controles não sendo submetidos à biópsia de congelação. Foram incluídos apenas os pacientes que tiveram critério e foram submetidos à re-RTUb. Um total de 150 pacientes foram randomizados, tornando-se elegíveis 131, sendo 64 no grupo 1 e 67 no grupo 2. Resultados: Comparando-se os grupos, não houve diferença em relação ao sexo, idade, quantidade e tamanho do tumor. No estudo anatomo-patológico da RTUb houve representatividade muscular em 100% x 58,5%, entre os grupos 1 e 2, respectivamente, com p < 0,001. Na Re-RTUb o índice de tumor residual foi 10,4% x 35,2%, entre os grupos 1 e 2, respectivamente, com p = 0,005. No grupo 1, 15 pacientes foram diagnosticados como pT2 com 100% do diagnóstico na primeira RTUb; no grupo 2, 6 pacientes tiveram diagnóstico de pT2 com apenas 33,3% na primeira RTUb, p=0,003. O tempo cirúrgico médio foi de 50 min no grupo 1 e 42min no grupo 2 (p= 0,037). Não houve diferença em relação à complicações (transfusão e perfuração vesical). Conclusão: A biópsia de congelação melhorou o correto estadiamento e controle local do câncer de bexiga, além de aumentar a acurácia do diagnóstico de doença pT2, podendo permitir o planejamento precoce do tratamento definitivo sem aumentar as complicações
Background and Purpose: Despite recent improvements of bladder cancer treatment, recurrence and progression rates are still high, possibly related to residual or overlooked tumors at the first transurethral resection (TUR), which strongly emphasizes the importance of the quality of this method. In order to improve the effectiveness of the procedure, we sought to evaluate the impact of frozen section during TUR, aiming on increasing muscular layer sample in the specimen, which may minimize incomplete resections and understaging. Patients and Methods: We prospectively included 150 consecutive patients assigned to TUR which were randomized to undergo either frozen section biopsy of the tumor bed during the TUR procedure until muscle was obtained or standard resection procedure (no frozen section). Nineteen patients were excluded after randomization, leaving 131 for analysis. All patients underwent a second TUR performed 4-6 weeks later. Frozen sections and final pathology reports were centralized and all performed by pathologists, the doubtful cases were reviewed by one uropathologist. Exclusion criteria: incomplete resection at first TUR, no criteria for second TUR according to EUA Guideline Update 2011 and previous bladder cancer treatment. (Group w/ biopsy, n = 64; Group control, n=67). Results: Both groups were comparable regarding age, gender, size and number of lesions. The majority of patients had high grade tumor in both groups. In the group where frozen section was obtained, muscle-invasive disease was higher (23% x 3%, p < 0,001). All patients in this group had muscle layer represented in the final pathology at the first TUR, while only 60% of patients in the control group (p < 0.001), including 40,5% of patients with pTa, 81,5% with pT1 e 100% with pT2 and Cis. Ninety percent of patients in the biopsy group had no residual tumor compared to 65% of the control group at second TUR (p=0,002). While all 15 patients in the frozen section group with T2 disease were diagnosed at first TUR, only 2 of 6 patients (33%) in the control group were diagnosed initially. The surgery duration was longer in the study group with mean of 50 min x 42 min (p=0,037) and there were no significant differences regarding complications (perforation and transfusion rates). Conclusion: Our results support the prove of principal that standard TUR with frozen section biopsy of bladder tumor bed increase the disease control and improve the diagnosis of T2 tumors, which may lead to reduced the number of patients in need a second TUR and avoid pT2 disease diagnosis delay, with no more complications
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Louhelainen, Jari. « Molecular progression and clonality or urinary bladder cancer / ». Stockholm, 2000.

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Karlsson, Mona. « Sentinel node based immunotherapy of cancer / ». Stockholm, 2007. http://diss.kib.ki.se/2007/978-91-7357-203-3/.

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Sjöström, Anna. « Radionuclide targeting with particular empahsis on urinary bladder carcinoma / ». Uppsala : Acta Universitatis Upsaliensis : Univ.-bibl. [distributör], 2001. http://publications.uu.se/theses/91-554-5035-0/.

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Pan, Yi. « Molecular cytogenetic investigations of chromosomal abnormalities in prostate and urinary bladder cancers / ». Stockholm, 2000. http://kib.ki.se/2000/91-628-4296-X/.

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Saowarin, Meechusupaya Sudarat Manochiopinij. « Urinary enzymes and carcinoembryonic antigen in patients with carcinoma of the bladder / ». Abstract, 1986. http://mulinet3.li.mahidol.ac.th/thesis/2529/29E-Saowarin-M.pdf.

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Livres sur le sujet "Urinary bladder neoplasia"

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Antonio, Lopez-Beltran, et Bostwick David G, dir. Bladder pathology. Hoboken, N.J : Wiley-Blackwell, 2012.

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1950-, Young Robert H., dir. Pathology of the urinary bladder. New York : Churchill Livingstone, 1989.

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Armed forces Institute of Pathology (U.S.), dir. Tumors of the urinary bladder. Washington, D.C : Armed Forces Institute of Pathology, 1985.

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Christopher, Foster, et Ross Jeffrey S. 1945-, dir. Pathology of the urinary bladder. Philadelphia : Saunders, 2004.

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J, Zingg Ernst, et Wallace, D. M. A. 1946-, dir. Bladder cancer. Berlin : Springer-Verlag, 1985.

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J, Manyak Michael, et Kahn Leonard B, dir. Bladder biopsy interpretation. New York : Raven Press, 1992.

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Pierfrancesco, Bassi, Fair William R et Pagano Francesco, dir. Superficial bladder cancer. Oxford : Isis Medical Media, 1997.

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1930-, Mackay Bruce, dir. Atlas of bladder pathology. New York : Igaku-Shoin, 1991.

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Derek, Raghavan, dir. The Management of bladder cancer. London : Edward Arnold, 1988.

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National Cancer Institute (U.S.), dir. What you need to know about bladder cancer. 2e éd. [Bethesda, Md.?] : National Institutes of Health, National Cancer Institute, 2001.

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Chapitres de livres sur le sujet "Urinary bladder neoplasia"

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Squire, Robert A. « Classification and Differential Diagnosis of Neoplasms, Urinary Bladder, Rat ». Dans Urinary System, 369–75. Berlin, Heidelberg : Springer Berlin Heidelberg, 1998. http://dx.doi.org/10.1007/978-3-642-80335-2_35.

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Squire, Robert A. « Classification and Differential Diagnosis of Neoplasms, Urinary Bladder, Rat ». Dans Urinary System, 311–17. Berlin, Heidelberg : Springer Berlin Heidelberg, 1986. http://dx.doi.org/10.1007/978-3-642-96956-0_38.

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Anderson, Christopher B., John E. Musser, John P. Sfakianos et Harry W. Herr. « Bladder Tumors : Association with Upper Tract Neoplasms ». Dans Upper Urinary Tract Urothelial Carcinoma, 91–107. Cham : Springer International Publishing, 2015. http://dx.doi.org/10.1007/978-3-319-13869-5_10.

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Bigongiari, Lawrence R., et Hilary Zarnow. « Traumatic, Inflammatory, Neoplastic, and Miscellaneous Lesions of the Bladder ». Dans Radiology of the Lower Urinary Tract, 69–147. Berlin, Heidelberg : Springer Berlin Heidelberg, 1994. http://dx.doi.org/10.1007/978-3-642-84431-7_6.

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Neuerburg, J. M., K. Bohndorf, M. Sohn, F. Teufl, R. W. Guenther et H. J. Daus. « Contrast-Enhanced MR Imaging of Urinary Bladder Neoplasms ». Dans Tissue Characterization in MR Imaging, 242–49. Berlin, Heidelberg : Springer Berlin Heidelberg, 1990. http://dx.doi.org/10.1007/978-3-642-74993-3_38.

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Dulewicz, Annamonika, Adam Jóźwik, Paweł Jaszczak et Bogusław D. Piȩtka. « Recognition of Neoplastic Changes in Digital Images of Exfoliated Nuclei of Urinary Bladder – A New Approach to Classification Method ». Dans Advances in Intelligent and Soft Computing, 479–87. Berlin, Heidelberg : Springer Berlin Heidelberg, 2009. http://dx.doi.org/10.1007/978-3-540-93905-4_57.

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Bebchuk, Trevor N. « URINARY BLADDER CALCULI AND NEOPLASIA ». Dans Small Animal Surgery Secrets, 206–11. Elsevier, 2004. http://dx.doi.org/10.1016/b978-1-56053-579-9.50059-7.

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Magi-Galluzzi, Cristina, Ming Zhou et Jonathan I. Epstein. « Neoplasms of the Urinary Bladder ». Dans Genitourinary Pathology, 154–224. Elsevier, 2007. http://dx.doi.org/10.1016/b978-0-443-06677-1.50009-0.

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Cheng, Liang, Antonio Lopez-Beltran, Gregory T. MacLennan, Rodolfo Montironi et David G. Bostwick. « Neoplasms of the urinary bladder ». Dans Urologic Surgical Pathology, 258–351. Elsevier, 2008. http://dx.doi.org/10.1016/b978-0-323-01970-5.50008-7.

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« Overview of Urinary Bladder Neoplasms ». Dans Diagnostic Pathology : Genitourinary, 328–31. Elsevier, 2016. http://dx.doi.org/10.1016/b978-0-323-37714-0.50071-7.

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Actes de conférences sur le sujet "Urinary bladder neoplasia"

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Piao, Daqing, Carole A. Davis, Robert E. Hurst et Joel W. Slaton. « In vivo fluorescence imaging of an orthotopic rat bladder tumor model indicates differential uptake of intravesically instilled near-infrared labeled 2-deoxyglucose analog by neoplastic urinary bladder tissues ». Dans SPIE BiOS, sous la direction de Hyun Wook Kang et Kin Foong Chan. SPIE, 2017. http://dx.doi.org/10.1117/12.2248358.

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Dias Filho, Marcelo Torres, Guilherme Eugenio Gil, João Victor Pereira Rocha, João Pedro Zanatto et Márcia Rocha Gabaldi Silva. « AVANÇOS DO TRATAMENTO DO CARCINOMA UROTELIAL NÃO-MÚSCULO INVASIVO : REVISÃO NARRATIVA ». Dans I SIMPÓSIO MARANHENSE DE GENÉTICA E GENÔMICA EM SAÚDE. Doity - Plataforma de Eventos, 2022. http://dx.doi.org/10.55664/simaggens2022.023.

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Résumé :
INTRODUÇÃO: O Carcinoma Urotelial, também conhecido como câncer de bexiga, é o décimo primeiro câncer mais comum em todo o mundo. O câncer de bexiga não-músculo invasivo (CBNMI) é um dos tipos que ocorre apenas no tecido fino da parede interna da bexiga, sem envolvimento do músculo e sem desenvolvimento para a parte externa da bexiga. O tratamento primário consiste na administração intravesical de Bacille Calmette Guérin (BCG), além de outros tratamentos baseados em anticorpos monoclonais direcionados e imunoterapia com células CAR-T. OBJETIVO: Revisar na literatura artigos científicos que apresentam estudos sobre os avanços em relação ao câncer de bexiga, observando-se o atual estágio das pesquisas e os obstáculos encontrados para o aprimoramento do tratamento, dando ênfase ao CBNMI. MÉTODOS: Foi realizada uma pesquisa bibliográfica entre 2020 e 2022 nas bases de dados PubMed e SciELLO usando na seleção as palavras-chave: “bladder cancer non muscle invasive”, “BCG”, “immunotherapy” e “urinary bladder neoplasms”. Na pesquisa foram encontrados 15 artigos científicos, os artigos foram analisados pelos seus títulos, seguida da leitura dos seus resumos e textos completos, para assim confirmar a relação dos artigos selecionados e o tema abordado neste trabalho. Foram selecionados 8 artigos neste trabalho. RESULTADOS E DISCUSSÃO: Observou-se que o tratamento com (BCG) intravesical foi a primeira terapia a ajudar a reduzir a progressão e os riscos de reincidência em câncer de bexiga não-músculo invasivo (CBNMI) de alto risco. Seu uso pode determinar uma resposta completa em aproximadamente 70% dos casos, com 60% dos pacientes podendo relatar uma nova recorrência em um ano. O BCG apresenta uma atual escassez mundial que vem resultando em esquema de priorização nas clínicas, concomitante a essa escassez, há outros obstáculos a serem superados, tais como os mecanismos de resistência da célula tumoral para escapar da resposta imune induzida pelo BCG. Tendo em vista esses mecanismos, avanços no uso da imunoterapia antiproteína de morte celular programada 1 (PD-1), vem se mostrando cada vez mais promissor, principalmente com a recente aprovação do Pembrolizumabe pela Food and Drug Administration (FDA), dos quais proporcionam uma diminuição nas doses de BCG, além de diminuírem eventos que levem a intolerância ao bacilo. Os esforços para evitar a falta de resposta do BCG vem do objetivo de atrasar ou até mesmo evitar a realização da cistectomia radical, que apresenta impacto na qualidade de vida, do qual é responsável pela morte de 10,6% dos pacientes em 90 dias. CONCLUSÃO: O tratamento do carcinoma urotelial não-músculo invasivo apresenta avanços com redução da progressão e diminuição dos riscos de recidiva, por meio do uso da BCG intravesical. Porém, a escassez de BCG e a necessidade de superar os mecanismos de resistência da célula tumoral. Torna necessário mais estudos para um tratamento eficaz e para se chagar a cura.
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