Littérature scientifique sur le sujet « Theological Translation Fund (London, England) »

AbstractThis article examines three occurrences of the sacrifice of Isaac in relatively recent cultural and political histories: the case of Godden versus Hales (England, 1686); Erich Auerbach's 'Odysseus' Scar' in Mimesis (Istanbul [Marburg], 1943-1945); and the use of the akedah as a political figure for the modern Israeli nation state. In these three very different cases the biblical narrative undergoes a theological-political translation and the God who issues the exceptional command to sacrifice becomes a figure for the sovereign and/or the state. Each political translation also calls forth critical responses in which the core question becomes the relationship of divine monarchy/state authority to freedom, or, to put it another way, of democracy or would-be 'democracy' to 'theocracy' and its various modern political correlates. By analysing these translations and responses, this essay explores how the questions as it were forced on us by Genesis 22 are not just religious, though they can be understood through the idioms of the religious. It concludes by asking whether such theological-political translations could be relevant to 'Biblical Studies Proper' as a more expansive discipline looks outwards to questions of religion, politics and ethics.

Nikolai Velimirovich was one of the most influential bishops of the Serbian Orthodox Church in the twentieth century. His stay in Britain in 1908/9 influenced his theological views and made him a proponent of an Anglican-Orthodox church reunion. As a known proponent of close relations between different Christian churches, he was sent by the Serbian Prime Minister Pasic to the United States (1915) and Britain (1915-1919) to work on promoting Serbia and the cause of Yugoslav unity. His activities in both countries were very successful. In Britain he closely collaborated with the Serbian Relief Fund and ?British friends of Serbia? (R. W. Seton-Watson, Henry Wickham Steed and Sir Arthur Evans). Other Serbian intellectuals in London, particularly the brothers Bogdan and Pavle Popovic, were in occasional collision with the members of the Yugoslav Committee over the nature of the future Yugoslav state. In contrast, Velimirovich remained committed to the cause of Yugoslav unity throughout the war with only rare moments of doubt. Unlike most other Serbs and Yugoslavs in London Father Nikolai never grew unsympathetic to the Serbian Prime Minister Pasic, although he did not share all of his views. In London he befriended the churchmen of the Church of England who propagated ecclesiastical reunion and were active in the Anglican and Eastern Association. These contacts allowed him to preach at St. Margaret?s Church, Westminster and other prominent Anglican churches. He became such a well-known and respected preacher that, in July 1917, he had the honour of being the first Orthodox clergyman to preach at St. Paul?s Cathedral. He was given the same honour in December 1919. By the end of the war he had very close relations with the highest prelates of the Church of England, the Catholic cardinal of Westminster, and with prominent clergymen of the Church of Scotland and other Protestant churches in Britain. Based on Velimirovich?s correspondence preserved in Belgrade and London archives, and on very wide coverage of his activities in The Times, in local British newspapers, and particularly in the Anglican journal The Church Times, this paper describes and analyses his wide-ranging activities in Britain. The Church of England supported him wholeheartedly in most of his activities and made him a celebrity in Britain during the Great War. It was thanks to this Church that some dozen of his pamphlets and booklets were published in London during the Great War. What made his relations with the Church of England so close was his commitment to the question of reunion of Orthodox churches with the Anglican Church. He suggested the reunion for the first time in 1909 and remained committed to it throughout the Great War. Analysing the activities of Father Nikolai, the paper also offers a survey of the very wide-ranging forms of help that the Church of England provided both to the Serbian Orthodox Church and to Serbs in by the end of the Great War he became a symbol of Anglican-Orthodox rapprochement. general during the Great War. Most of these activities were channelled through him. Thus, by the end of the Great War he became a symbol of Anglican-Orthodox rapprochement.

The use of the term authenticity in the social science literature can be rather eclectic at best and unscrupulous at worst. (Vanini, 74)We live in an age of authenticity, according to Charles Taylor, an era which prizes the finding of one’s life “against the demands of external conformity” (67–68). Taylor’s argument is that, correctly practiced, authenticity need not result in individualism or tribalism but rather a generation of people “made more self-responsible” (77).Philip Vanini has surveyed the turn toward authenticity in sociology. He has parsed the word authenticity, and argued that it has been used in three ways—factual, original, and sincere. A failure to attend to these distinctives, mixed with a “paucity of systematic empirical research” has resulted in abstract speculation (75). This article responds to Taylor’s analysis and Vanini’s challenge.My argument utilises Vanini’s theoretical frame—authenticity as factual, original, and sincere—to analyse empirical data gathered in the study of recent religious innovation occurring amongst a set of (“alternative worship”) Christian communities in the United Kingdom. I am drawing upon longitudinal research I have conducted, including participant observation in digital forums from 1997 to the present, along with semi-structured interviews conducted in the United Kingdom in 2001 and 2012.A study of “alternative worship” was deemed significant given such communities’s interaction with contemporary culture, including their use of dance music, multi-media, and social media (Baker, Taylor). Such approaches contrast with other contemporary religious approaches to culture, including a fundamentalist retreat from culture or the maintenance of a “high” culture, and thus inherited patterns of religious expression (Roberts).I argue that the discourse of “alternative worship” deploy authenticity-as-originality as essential to their identity creation. This notion of authenticity is used by these communities to locate themselves culturally (as authentically-original in contemporary cultures), and thus simultaneously to define themselves as marginal from mainstream religious expression.Intriguingly, a decade later, “alternative worship” was appropriated by the mainstream. A new organisation—Fresh Expressions—emerged from within the Church of England, and the Methodist Church in Britain that, as it developed, drew on “alternative worship” for legitimation. A focus on authenticity provides a lens by which to pay particular attention to the narratives offered by social organisations in the processes of innovation. How did the discourse deployed by Fresh Expressions in creating innovation engage “alternative worship” as an existing innovation? How did these “alternative worship” groups, who had found generative energy in their location as an alternative—authentically-original—expression, respond to this appropriation by mainstream religious life?A helpful conversation partner in teasing out the complexity of these moves within contemporary religious innovation is Sarah Thornton. She researched trends in dance clubs, and rave music in Britain, during a similar time period. Thornton highlighted the value of authenticity, which she argued was deployed in club cultures to create “subcultural capital” (98-105). She further explored how the discourses around authenticity were appropriated over time through the complex networks within which popular culture flows (Bennett; Collins; Featherstone; McRobbie; Willis).This article will demonstrate that a similar pattern—using authenticity-as-originality to create “subcultural capital”—was at work in “alternative worship.” Further, the notions of authenticity as factual, original, and sincere are helpful in parsing the complex networks that exist within the domains of religious cultures. This analysis will be two-fold, first as the mainstream appropriates, and second as the “alternative” responds.Thornton emerged “post-Birmingham.” She drew on the scholarship associated with the Centre for Contemporary Cultural Studies, glad of their turn toward popular culture. Nevertheless she considered her work to be distinct. Thornton posited the construction of “taste cultures” through distinctions created by those inside a particular set of signs and symbols. She argued for a networked view of society, one that recognised the complex roles of media and commerce in constructing distinctions and sought a more multi-dimensional frame by which to analyse the interplay between mainstream and marginal.In order to structure my investigation, I am suggesting three stages of development capture the priority, yet complexity, of authenticity in contemporary religious innovation: generation, appropriation, complexification.Generation of Authenticity-as-OriginalityThornton (26, italics original) writes:authenticity is arguably the most important value ascribed to popular music … Music is perceived as authentic when it rings true or feels real, when it has credibility and comes across as genuine. In an age of endless representations and global mediation, the experience of musical authenticity is perceived as a cure both for alienation … and dissimulation.Thornton is arguing that in this manifestation of youth culture, authenticity is valued. Further, authenticity is a perception, attached to phrases like “rings true” and “feels real.” Therefore, authenticity is hard to measure. Perhaps this move is deliberate, an attempt by those inside the “taste culture” to preserve their “subcultural capital,”—their particular sets of distinctions.Thornton’s use of authentic slides between authenticity-as-sincerity and authenticity-as-originality. For example, in the above quote, the language of “true” and “real” is a referencing of authenticity-as-sincerity. However, as Thornton analysed the appropriation of club culture by the mainstream, she is drawing, without stating it clearly, on both authenticity-as-sincerity and authenticity-as-originality.At around the time that Thornton was analysing club cultures, a number of Christian religious groups in the United Kingdom began to incorporate features of club culture into their worship services. Churches began to experiment with services beginning at club times (9.00 pm), the playing of dance music, and the use of “video-jockeying.” According to Roberts many of these worshipping communities “had close links to this movement in dance culture” (15).A discourse of authenticity was used to legitimise such innovation. Consider the description of one worship experience, located in Sheffield, England, known as Nine o’Clock Service (Fox 9-10, italics original).We enter a round, darkened room where there are forty-two television sets and twelve large video screens and projections around the walls—projections of dancing DNA, dancing planets and galaxies and atoms … this was a very friendly place for a generation raised on television and images … these people … are doing it themselves and in the center of the city and in the center of their society: at worship itself.This description makes a number of appeals to authenticity. The phrase “a generation raised on television and images” implies another generation not raised in digitally rich environments. A “subcultural” distinction has been created. The phrase “doing it themselves” suggests that this ‘digital generation’ creates something distinct, an authentic expression of their “taste culture.” The celebration of “doing it for themselves” resonates with Charles Taylor’s analysis of an age of authenticity in which self-discovery is connected with artistic creation (62).The Nine o’Clock Service gained nationwide attention, attracting attendances of over 600 young people. Rogerson described it as “a bold and imaginative attempt at contextual theology … people were attracted to it in the first instance for aesthetic and cultural reasons” (51). The priority on the aesthetic and the cultural, in contrast to the doctrinal, suggests a valuing of authenticity-as-originality.Reading Rogerson alongside Taylor teases out a further nuance in regard to the application of authenticity. Rogerson described the Nine o’Clock Service as offering “an alternative way of living in a materialist and acquisitive world” (50). This resonates with Charles Taylor’s argument that authenticity can be practiced in ways that make people “more self-responsible” (77). It suggests that the authenticity-as-originality expressed by the Nine o’Clock Service not only appealed culturally, but also offered an ethic of authenticity. We will return to this later in my argument.Inspired by the Nine o’Clock Service, other groups in the United Kingdom began to offer a similar experience. According to Adrian Riley (6):The Nine O’clock Service … was the first worshipping community to combine elements of club culture with passionate worship … It pioneered what is commonly known as “alternative worship” … Similar groups were established themselves albeit on a smaller scale.The very term “alternative worship” is significant. Sociologist of religion Abby Day argued that “boundary-marking [creates] an identity” (50). Applying Day, the term “alternative” is being used to create an identity in contrast to the existing, mainstream church. The “digitally rich” are indeed “doing it for themselves.” To be “alternative” is to be authentically-original: to be authentically-original means a participant cannot, by definition, be mainstream.Thornton argued that subcultures needed to define themselves against in order to maintain themselves as “hip” (119). This seems to describe the use of the term “alternative.” Ironically, the mainstream is needed, in order to define against, to create identity by being authentically-original (Kelly).Hence the following claim by an “alternative worship” organiser (Interview G, 2001):People were willing to play around and to say, well who knows what will happen if we run this video clip or commercial next to this sixteenth century religious painting and if we play, you know, Black Flag or some weird band underneath it … And what will it feel like? Well let’s try it and see.Note the link with music (Black Flag, an American hard core punk band formed in 1976), so central to Thornton’s understanding of authenticity in popular youth cultures. Note also the similarity between Thornton’s ascribing of value in words like “rings true” and “feels real,” with words like “feel like” and “try and see.” The word “weird” is also significant. It is deployed as a signifier of authenticity, a sign of “subcultural capital.” It positions them as “alternative,” defined in (musical) distinction from the mainstream.In sum, my argument is that authenticity-as-originality is present in “alternative worship”: in the name, in the ethos of “doing it themselves,” and in the deploying of “subcultural capital” in the legitimation of innovation. All of this has been clarified through conversation with Thornton’s empirical research regarding the value of authenticity in club culture. My analysis of “alternative worship” as a religious innovation is consistent with Taylor’s claim that we inhabit an age of authenticity, one that can be practiced by “people who are made more self-responsible” (77).Mainstream AppropriationIn 2004, the Church of England produced Mission Shaped Church (MSC), a report regarding its future. It included a chapter that described recent religious innovation in England, grouped under twelve headings (alternative worship and base ecclesial communities, café, cell, network and seeker church models, multiple and mid week congregations, new forms of traditional churches, school and community-based initiatives, traditional church plants, youth congregations). The first innovation listed is “alternative worship.”The incoming Archbishop, Rowan Williams, drew on MSC to launch a new organisation. Called Fresh Expressions, over five million pounds was provided by the Church of England to fund an organisation to support this religious innovation.Intriguingly, recognition of authenticity in these “alternative” innovations was evident in the institutional discourse being created. When I interviewed Williams, he spoke of his commitment as a Bishop (Interview 6, 2012):I decided to spend a certain amount of quality time with people on the edge. Consequently when I was asked initially what are my priorities [as Archbishop] I said, “Well, this is what I’ve been watching on the edge … I really want to see how that could impact on the Church of England as a whole.In other words, what was marginal, what had until then generated identity by being authentic in contrast to the mainstream, was now being appropriated by the mainstream “to impact on the Church of England as a whole.” MSC was aware of this complexity. “Alternative worship” was described as containing “a strong desire to be different and is most vocal in its repudiation of existing church” (45). Nevertheless, it was appropriated by the mainstream.My argument has been that “alternative worship” drew on a discourse of authenticity-as-originality. Yet when we turn to analyse mainstream appropriation, we find the definitions of authenticity begin to slide. Authenticity-as-originality is affirmed, while authenticity-as-sincerity is introduced. The MSC affirmed the “ways in which the Church of England has sought to engage with the diverse cultures and networks that are part of contemporary life” (80). It made explicit the connection between originality and authenticity. “Some pioneers and leaders have yearned for a more authentic way of living, being, doing church” (80). This can be read as an affirmation of authenticity-as-originality.Yet MSC also introduced authenticity-as-sincerity as a caution to authenticity-as-originality. “Fresh expressions should not be embraced simply because they are popular and new, but because they are a sign of the work of God and of the kingdom” (80). Thus Fresh Expressions introduced authenticity-as-sincerity (sign of the work of God) and placed it alongside authenticity-as-originality. In so doing, in the shift from “alternative worship” to Fresh Expressions, a space is both conflated (twelve expressions of church) and contested (two notions of authenticity). Conflated, because MSC places alternative worship as one innovation alongside eleven others. Contested because of the introduction of authenticity-as-sincerity alongside the affirming of authenticity-as-originality. What is intriguing is to return to Taylor’s argument for the possibility of an ethic of authenticity in which “people are made more self-responsible” (77). Perhaps the response in MSC arises from the concern described by Taylor, the risk in an age of authenticity of a society that is more individualised and tribal (55-6). To put it in distinctly ecclesiological terms, how can the church as one, holy, catholic and apostolic be carried forward if authenticity-as-originality is celebrated at, and by, the margins? Does innovation contribute to more atomised, self-absorbed and fragmented expressions of church?Yet Taylor is adamant that authenticity can be embraced without an inevitable slide in these directions. He argued that humans share a "horizon of significance" in common (52), in which one’s own "identity crucially depends on [one’s] dialogical relations with others" (48). We have already considered Rogerson’s claim that the Nine o’Clock Service offered “an alternative way of living in a materialist and acquisitive world” (50). It embraced a “strong political dimension, and a concern for justice at local and international level” (46). In other words, “alternative worship’s” authenticity-as-originality was surely already an expression of “the kingdom,” one in which “people [were] made more self-responsible” (77) in the sharing of (drawing on Taylor) a "horizon of significance" in the task of identity-formation-in-relationships (52).Yet the placing in MSC of authenticity-as-sincerity alongside authenticity-as-originality could easily have been read by those in “alternative worship” as a failure to recognise their existing practicing of the ethic of authenticity, their embodying of “the kingdom.”Consequent ComplexificationMy research into “alternative worship” is longitudinal. After the launch of Fresh Expressions, I included a new set of interview questions, which sought to clarify how these “alternative worship” communities were impacted upon by the appropriation of “alternative worship” by the mainstream. The responses can be grouped into three categories: minimal impact, a sense of affirmation and a contested complexity.With regard to minimal impact, some “alternative worship” communities perceived the arrival of Fresh Expressions had minimal impact on their shared expression of faith. The following quote was representative: “Has had no impact at all actually. Apart from to be slightly puzzled” (Interview 3, 2012).Others found the advent of Fresh Expressions provided a sense of affirmation. “Fresh expressions is … an enabling concept. It was very powerful” (Focus group 2, 2012). Respondents in this category felt that their innovations within alternative worship had contributed to, or been valued by, the innovation of Fresh Expressions. Interestingly, those whose comments could be grouped in this category had significant “subcultural capital” invested in this mainstream appropriation. Specifically, they now had a vocational role that in some way was connected to Fresh Expressions. In using the term “subcultural capital” I am again drawing on Thornton (98–105), who argued that in the complex networks through which culture flows, certain people, for example DJ’s, have more influence in the ascribing of authenticity. This suggests that “subcultural” capital is also present in religious innovation, with certain individuals finding ways to influence, from the “alternative worship” margin, the narratives of authenticity used in the complex interplay between alternative worship and Fresh Expressions.For others the arrival of Fresh Expressions had resulted in a contested complexity. The following quote was representative: “It’s a crap piece of establishment branding …but then we’re just snobs” (Focus group 3, 2012). This comment returns us to my initial framing of authenticity-as-originality. I would argue that “we’re just snobs” has a similar rhetorical effect as “Black Flag or some weird band.” It is an act of marginal self-location essential in the construction of innovation and identity.This argument is strengthened given the fact that the comment was coming from a community that itself had become perhaps the most recognizable “brand” among “alternative worship.” They have developed their own logo, website, and related online merchandising. This would suggest the concern is not the practice of marketing per se. Rather the concern is that it seems “crap” in relation to authenticity-as-originality, in a loss of aesthetic quality and a blurring of the values of innovation and identity as it related to bold, imaginative, aesthetic, and cultural attempts at contextual theology (Rogerson 51).Returning to Thornton, her research was also longitudinal in that she explored what happened when a song from a club, which had defined itself against the mainstream and as “hip,” suddenly experienced mainstream success (119). What is relevant to this investigation into religious innovation is her argument that in club culture, “selling out” is perceived to have happened only when the marginal community “loses its sense of possession, exclusive ownership and familiar belonging” (124–26).I would suggest that this is what is happening within “alternative worship” in response to the arrival of Fresh Expressions. Both “alternative worship” and Fresh Expressions are religious innovations. But Fresh Expressions defined itself in a way that conflated the space. It meant that the boundary marking so essential to “alternative worship” was lost. Some gained from this. Others struggled with a loss of imaginative and cultural creativity, a softening of authenticity-as-originality.More importantly, the discourse around Fresh Expressions also introduced authenticity-as-sincerity as a value that could be used to contest authenticity-as-originality. Whether intended or not, this also challenged the ethic of authenticity already created by these “alternative worship” communities. Their authenticity-as-originality was already a practicing of an ethic of authenticity. They were already sharing a "horizon of significance" with humanity, entering into “dialogical relations with others" that were a contemporary expression of the church as one, holy, catholic and apostolic (Taylor 52, 48). ConclusionIn this article I have analysed the discourse around authenticity as it is manifest within one strand of contemporary religious innovation. Drawing on Vanini, Taylor, and Thornton, I have explored the generative possibilities as media and culture are utilised in an “alternative worship” that is authentically-original. I have outlined the consequences when authenticity-as-originality is appropriated by the mainstream, specifically in the innovation known as Fresh Expressions and the complexity when authenticity-as-sincerity is introduced as a contested value.The value of authenticity has been found to exist in a complex relationship with the ethics of authenticity within one domain of contemporary religious innovation.ReferencesBaker, Jonny. “Alternative Worship and the Significance of Popular Culture.” Honours paper: U of London, 2000.Bennett, Andy. Popular Music and Youth Culture: Music, Identity, and Place. New York: Palgrave, 2000.Cronshaw, Darren, and Steve Taylor. “The Congregation in a Pluralist Society: Rereading Newbigin for Missional Churches Today.” Pacifica: Australasian Theological Studies 27.2 (2014): 1-24.Day, Abby. Believing in Belonging. Belief and Social Identity in the Modern World. Oxford: Oxford UP, 2011.Collins, Jim, ed. High-Pop. Making Culture into Popular Entertainment. Oxford: Blackwells, 2002.Cray, Graham. Mission-Shaped Church: Church Planting and Fresh Expressions of Church in a Changing Culture, London: Church House Publishing, 2004.Featherstone, Mike. Consumer Culture and Postmodernism. London: Sage, 1991.Fox, Matthew. Confessions: The Making of a Post-Denominational Priest. San Francisco: Harper San Francisco, 1996.Guest, Matthew, and Steve Taylor. “The Post-Evangelical Emerging Church: Innovations in New Zealand and the UK.” International Journal for the Study of the Christian Church 6.1 (2006): 49-64.Howard, Roland. The Rise and Fall of the Nine o’Clock Service. London: Continuum, 1996.Kelly, Gerard. Get a Grip on the Future without Losing Your Hold in the Past. Great Britain: Monarch, 1999.Kelly, Steven. “Book Review. Alt.Culture by Steven Daly and Nathaniel Wice.” 20 Aug. 2003. ‹http://www.richmondreview.co.uk/books/cult.html›.McRobbie, Angela. Postmodernism and Popular Culture. London: Routledge, 1994.Riley, Adrian. God in the House: UK Club Culture and Spirituality. 1999. 15 Oct. 2003 ‹http://www.btmc.org.auk/altworship/house/›.Roberts, Paul. Alternative Worship in the Church of England. Cambridge: Grove Books, 1999.Rogerson, J. W. “‘The Lord Is here’: The Nine o’Clock Service.” Why Liberal Churches Are Growing. Eds. Ian Markham and Martyn Percy. London: Bloomsbury T & T, 2006. 45-52.Taylor, Charles. The Ethics of Authenticity. Cambridge: Harvard UP, 1992.Taylor, Steve. “Baptist Worship and Contemporary Culture: A New Zealand Case Study.” Interfaces: Baptists and Others. Eds. David Bebbington and Martin Sutherland. Carlisle: Paternoster, 2013. 292-307.Thornton, Sarah. Club Cultures. Music, Media and Subcultural Capital. Hanover: UP New England, 1996.Vanini, Philip. “Authenticity.” Encyclopedia of Consumer Culture. Ed. Dale Southerton. Los Angeles: Sage, 2011. 74-76.Willis, Paul E., et al. Common Culture. Symbolic Work at Play in the Everyday Cultures of the Young. Milton Keynes: Open UP, 1990.

Photo ID 158378414 © Eduard Muzhevskyi | Dreamstime.com ABSTRACT There is a debate about the ethical implications of using human embryos in stem cell research, which can be influenced by cultural, moral, and social values. This paper argues for an adaptable framework to accommodate diverse cultural and religious perspectives. By using an adaptive ethics model, research protections can reflect various populations and foster growth in stem cell research possibilities. INTRODUCTION Stem cell research combines biology, medicine, and technology, promising to alter health care and the understanding of human development. Yet, ethical contention exists because of individuals’ perceptions of using human embryos based on their various cultural, moral, and social values. While these disagreements concerning policy, use, and general acceptance have prompted the development of an international ethics policy, such a uniform approach can overlook the nuanced ethical landscapes between cultures. With diverse viewpoints in public health, a single global policy, especially one reflecting Western ethics or the ethics prevalent in high-income countries, is impractical. This paper argues for a culturally sensitive, adaptable framework for the use of embryonic stem cells. Stem cell policy should accommodate varying ethical viewpoints and promote an effective global dialogue. With an extension of an ethics model that can adapt to various cultures, we recommend localized guidelines that reflect the moral views of the people those guidelines serve. BACKGROUND Stem cells, characterized by their unique ability to differentiate into various cell types, enable the repair or replacement of damaged tissues. Two primary types of stem cells are somatic stem cells (adult stem cells) and embryonic stem cells. Adult stem cells exist in developed tissues and maintain the body’s repair processes.[1] Embryonic stem cells (ESC) are remarkably pluripotent or versatile, making them valuable in research.[2] However, the use of ESCs has sparked ethics debates. Considering the potential of embryonic stem cells, research guidelines are essential. The International Society for Stem Cell Research (ISSCR) provides international stem cell research guidelines. They call for “public conversations touching on the scientific significance as well as the societal and ethical issues raised by ESC research.”[3] The ISSCR also publishes updates about culturing human embryos 14 days post fertilization, suggesting local policies and regulations should continue to evolve as ESC research develops.[4] Like the ISSCR, which calls for local law and policy to adapt to developing stem cell research given cultural acceptance, this paper highlights the importance of local social factors such as religion and culture. I. Global Cultural Perspective of Embryonic Stem Cells Views on ESCs vary throughout the world. Some countries readily embrace stem cell research and therapies, while others have stricter regulations due to ethical concerns surrounding embryonic stem cells and when an embryo becomes entitled to moral consideration. The philosophical issue of when the “someone” begins to be a human after fertilization, in the morally relevant sense,[5] impacts when an embryo becomes not just worthy of protection but morally entitled to it. The process of creating embryonic stem cell lines involves the destruction of the embryos for research.[6] Consequently, global engagement in ESC research depends on social-cultural acceptability. a. US and Rights-Based Cultures In the United States, attitudes toward stem cell therapies are diverse. The ethics and social approaches, which value individualism,[7] trigger debates regarding the destruction of human embryos, creating a complex regulatory environment. For example, the 1996 Dickey-Wicker Amendment prohibited federal funding for the creation of embryos for research and the destruction of embryos for “more than allowed for research on fetuses in utero.”[8] Following suit, in 2001, the Bush Administration heavily restricted stem cell lines for research. However, the Stem Cell Research Enhancement Act of 2005 was proposed to help develop ESC research but was ultimately vetoed.[9] Under the Obama administration, in 2009, an executive order lifted restrictions allowing for more development in this field.[10] The flux of research capacity and funding parallels the different cultural perceptions of human dignity of the embryo and how it is socially presented within the country’s research culture.[11] b. Ubuntu and Collective Cultures African bioethics differs from Western individualism because of the different traditions and values. African traditions, as described by individuals from South Africa and supported by some studies in other African countries, including Ghana and Kenya, follow the African moral philosophies of Ubuntu or Botho and Ukama, which “advocates for a form of wholeness that comes through one’s relationship and connectedness with other people in the society,”[12] making autonomy a socially collective concept. In this context, for the community to act autonomously, individuals would come together to decide what is best for the collective. Thus, stem cell research would require examining the value of the research to society as a whole and the use of the embryos as a collective societal resource. If society views the source as part of the collective whole, and opposes using stem cells, compromising the cultural values to pursue research may cause social detachment and stunt research growth.[13] Based on local culture and moral philosophy, the permissibility of stem cell research depends on how embryo, stem cell, and cell line therapies relate to the community as a whole. Ubuntu is the expression of humanness, with the person’s identity drawn from the “’I am because we are’” value.[14] The decision in a collectivistic culture becomes one born of cultural context, and individual decisions give deference to others in the society. Consent differs in cultures where thought and moral philosophy are based on a collective paradigm. So, applying Western bioethical concepts is unrealistic. For one, Africa is a diverse continent with many countries with different belief systems, access to health care, and reliance on traditional or Western medicines. Where traditional medicine is the primary treatment, the “’restrictive focus on biomedically-related bioethics’” [is] problematic in African contexts because it neglects bioethical issues raised by traditional systems.”[15] No single approach applies in all areas or contexts. Rather than evaluating the permissibility of ESC research according to Western concepts such as the four principles approach, different ethics approaches should prevail. Another consideration is the socio-economic standing of countries. In parts of South Africa, researchers have not focused heavily on contributing to the stem cell discourse, either because it is not considered health care or a health science priority or because resources are unavailable.[16] Each country’s priorities differ given different social, political, and economic factors. In South Africa, for instance, areas such as maternal mortality, non-communicable diseases, telemedicine, and the strength of health systems need improvement and require more focus[17] Stem cell research could benefit the population, but it also could divert resources from basic medical care. Researchers in South Africa adhere to the National Health Act and Medicines Control Act in South Africa and international guidelines; however, the Act is not strictly enforced, and there is no clear legislation for research conduct or ethical guidelines.[18] Some parts of Africa condemn stem cell research. For example, 98.2 percent of the Tunisian population is Muslim.[19] Tunisia does not permit stem cell research because of moral conflict with a Fatwa. Religion heavily saturates the regulation and direction of research.[20] Stem cell use became permissible for reproductive purposes only recently, with tight restrictions preventing cells from being used in any research other than procedures concerning ART/IVF. Their use is conditioned on consent, and available only to married couples.[21] The community's receptiveness to stem cell research depends on including communitarian African ethics. c. Asia Some Asian countries also have a collective model of ethics and decision making.[22] In China, the ethics model promotes a sincere respect for life or human dignity,[23] based on protective medicine. This model, influenced by Traditional Chinese Medicine (TCM), [24] recognizes Qi as the vital energy delivered via the meridians of the body; it connects illness to body systems, the body’s entire constitution, and the universe for a holistic bond of nature, health, and quality of life.[25] Following a protective ethics model, and traditional customs of wholeness, investment in stem cell research is heavily desired for its applications in regenerative therapies, disease modeling, and protective medicines. In a survey of medical students and healthcare practitioners, 30.8 percent considered stem cell research morally unacceptable while 63.5 percent accepted medical research using human embryonic stem cells. Of these individuals, 89.9 percent supported increased funding for stem cell research.[26] The scientific community might not reflect the overall population. From 1997 to 2019, China spent a total of $576 million (USD) on stem cell research at 8,050 stem cell programs, increased published presence from 0.6 percent to 14.01 percent of total global stem cell publications as of 2014, and made significant strides in cell-based therapies for various medical conditions.[27] However, while China has made substantial investments in stem cell research and achieved notable progress in clinical applications, concerns linger regarding ethical oversight and transparency.[28] For example, the China Biosecurity Law, promoted by the National Health Commission and China Hospital Association, attempted to mitigate risks by introducing an institutional review board (IRB) in the regulatory bodies. 5800 IRBs registered with the Chinese Clinical Trial Registry since 2021.[29] However, issues still need to be addressed in implementing effective IRB review and approval procedures. The substantial government funding and focus on scientific advancement have sometimes overshadowed considerations of regional cultures, ethnic minorities, and individual perspectives, particularly evident during the one-child policy era. As government policy adapts to promote public stability, such as the change from the one-child to the two-child policy,[30] research ethics should also adapt to ensure respect for the values of its represented peoples. Japan is also relatively supportive of stem cell research and therapies. Japan has a more transparent regulatory framework, allowing for faster approval of regenerative medicine products, which has led to several advanced clinical trials and therapies.[31] South Korea is also actively engaged in stem cell research and has a history of breakthroughs in cloning and embryonic stem cells.[32] However, the field is controversial, and there are issues of scientific integrity. For example, the Korean FDA fast-tracked products for approval,[33] and in another instance, the oocyte source was unclear and possibly violated ethical standards.[34] Trust is important in research, as it builds collaborative foundations between colleagues, trial participant comfort, open-mindedness for complicated and sensitive discussions, and supports regulatory procedures for stakeholders. There is a need to respect the culture’s interest, engagement, and for research and clinical trials to be transparent and have ethical oversight to promote global research discourse and trust. d. Middle East Countries in the Middle East have varying degrees of acceptance of or restrictions to policies related to using embryonic stem cells due to cultural and religious influences. Saudi Arabia has made significant contributions to stem cell research, and conducts research based on international guidelines for ethical conduct and under strict adherence to guidelines in accordance with Islamic principles. Specifically, the Saudi government and people require ESC research to adhere to Sharia law. In addition to umbilical and placental stem cells,[35] Saudi Arabia permits the use of embryonic stem cells as long as they come from miscarriages, therapeutic abortions permissible by Sharia law, or are left over from in vitro fertilization and donated to research.[36] Laws and ethical guidelines for stem cell research allow the development of research institutions such as the King Abdullah International Medical Research Center, which has a cord blood bank and a stem cell registry with nearly 10,000 donors.[37] Such volume and acceptance are due to the ethical ‘permissibility’ of the donor sources, which do not conflict with religious pillars. However, some researchers err on the side of caution, choosing not to use embryos or fetal tissue as they feel it is unethical to do so.[38] Jordan has a positive research ethics culture.[39] However, there is a significant issue of lack of trust in researchers, with 45.23 percent (38.66 percent agreeing and 6.57 percent strongly agreeing) of Jordanians holding a low level of trust in researchers, compared to 81.34 percent of Jordanians agreeing that they feel safe to participate in a research trial.[40] Safety testifies to the feeling of confidence that adequate measures are in place to protect participants from harm, whereas trust in researchers could represent the confidence in researchers to act in the participants’ best interests, adhere to ethical guidelines, provide accurate information, and respect participants’ rights and dignity. One method to improve trust would be to address communication issues relevant to ESC. Legislation surrounding stem cell research has adopted specific language, especially concerning clarification “between ‘stem cells’ and ‘embryonic stem cells’” in translation.[41] Furthermore, legislation “mandates the creation of a national committee… laying out specific regulations for stem-cell banking in accordance with international standards.”[42] This broad regulation opens the door for future global engagement and maintains transparency. However, these regulations may also constrain the influence of research direction, pace, and accessibility of research outcomes. e. Europe In the European Union (EU), ethics is also principle-based, but the principles of autonomy, dignity, integrity, and vulnerability are interconnected.[43] As such, the opportunity for cohesion and concessions between individuals’ thoughts and ideals allows for a more adaptable ethics model due to the flexible principles that relate to the human experience The EU has put forth a framework in its Convention for the Protection of Human Rights and Dignity of the Human Being allowing member states to take different approaches. Each European state applies these principles to its specific conventions, leading to or reflecting different acceptance levels of stem cell research. [44] For example, in Germany, Lebenzusammenhang, or the coherence of life, references integrity in the unity of human culture. Namely, the personal sphere “should not be subject to external intervention.”[45] Stem cell interventions could affect this concept of bodily completeness, leading to heavy restrictions. Under the Grundgesetz, human dignity and the right to life with physical integrity are paramount.[46] The Embryo Protection Act of 1991 made producing cell lines illegal. Cell lines can be imported if approved by the Central Ethics Commission for Stem Cell Research only if they were derived before May 2007.[47] Stem cell research respects the integrity of life for the embryo with heavy specifications and intense oversight. This is vastly different in Finland, where the regulatory bodies find research more permissible in IVF excess, but only up to 14 days after fertilization.[48] Spain’s approach differs still, with a comprehensive regulatory framework.[49] Thus, research regulation can be culture-specific due to variations in applied principles. Diverse cultures call for various approaches to ethical permissibility.[50] Only an adaptive-deliberative model can address the cultural constructions of self and achieve positive, culturally sensitive stem cell research practices.[51] II. Religious Perspectives on ESC Embryonic stem cell sources are the main consideration within religious contexts. While individuals may not regard their own religious texts as authoritative or factual, religion can shape their foundations or perspectives. The Qur'an states: “And indeed We created man from a quintessence of clay. Then We placed within him a small quantity of nutfa (sperm to fertilize) in a safe place. Then We have fashioned the nutfa into an ‘alaqa (clinging clot or cell cluster), then We developed the ‘alaqa into mudgha (a lump of flesh), and We made mudgha into bones, and clothed the bones with flesh, then We brought it into being as a new creation. So Blessed is Allah, the Best of Creators.”[52] Many scholars of Islam estimate the time of soul installment, marked by the angel breathing in the soul to bring the individual into creation, as 120 days from conception.[53] Personhood begins at this point, and the value of life would prohibit research or experimentation that could harm the individual. If the fetus is more than 120 days old, the time ensoulment is interpreted to occur according to Islamic law, abortion is no longer permissible.[54] There are a few opposing opinions about early embryos in Islamic traditions. According to some Islamic theologians, there is no ensoulment of the early embryo, which is the source of stem cells for ESC research.[55] In Buddhism, the stance on stem cell research is not settled. The main tenets, the prohibition against harming or destroying others (ahimsa) and the pursuit of knowledge (prajña) and compassion (karuna), leave Buddhist scholars and communities divided.[56] Some scholars argue stem cell research is in accordance with the Buddhist tenet of seeking knowledge and ending human suffering. Others feel it violates the principle of not harming others. Finding the balance between these two points relies on the karmic burden of Buddhist morality. In trying to prevent ahimsa towards the embryo, Buddhist scholars suggest that to comply with Buddhist tenets, research cannot be done as the embryo has personhood at the moment of conception and would reincarnate immediately, harming the individual's ability to build their karmic burden.[57] On the other hand, the Bodhisattvas, those considered to be on the path to enlightenment or Nirvana, have given organs and flesh to others to help alleviate grieving and to benefit all.[58] Acceptance varies on applied beliefs and interpretations. Catholicism does not support embryonic stem cell research, as it entails creation or destruction of human embryos. This destruction conflicts with the belief in the sanctity of life. For example, in the Old Testament, Genesis describes humanity as being created in God’s image and multiplying on the Earth, referencing the sacred rights to human conception and the purpose of development and life. In the Ten Commandments, the tenet that one should not kill has numerous interpretations where killing could mean murder or shedding of the sanctity of life, demonstrating the high value of human personhood. In other books, the theological conception of when life begins is interpreted as in utero,[59] highlighting the inviolability of life and its formation in vivo to make a religious point for accepting such research as relatively limited, if at all.[60] The Vatican has released ethical directives to help apply a theological basis to modern-day conflicts. The Magisterium of the Church states that “unless there is a moral certainty of not causing harm,” experimentation on fetuses, fertilized cells, stem cells, or embryos constitutes a crime.[61] Such procedures would not respect the human person who exists at these stages, according to Catholicism. Damages to the embryo are considered gravely immoral and illicit.[62] Although the Catholic Church officially opposes abortion, surveys demonstrate that many Catholic people hold pro-choice views, whether due to the context of conception, stage of pregnancy, threat to the mother’s life, or for other reasons, demonstrating that practicing members can also accept some but not all tenets.[63] Some major Jewish denominations, such as the Reform, Conservative, and Reconstructionist movements, are open to supporting ESC use or research as long as it is for saving a life.[64] Within Judaism, the Talmud, or study, gives personhood to the child at birth and emphasizes that life does not begin at conception:[65] “If she is found pregnant, until the fortieth day it is mere fluid,”[66] Whereas most religions prioritize the status of human embryos, the Halakah (Jewish religious law) states that to save one life, most other religious laws can be ignored because it is in pursuit of preservation.[67] Stem cell research is accepted due to application of these religious laws. We recognize that all religions contain subsets and sects. The variety of environmental and cultural differences within religious groups requires further analysis to respect the flexibility of religious thoughts and practices. We make no presumptions that all cultures require notions of autonomy or morality as under the common morality theory, which asserts a set of universal moral norms that all individuals share provides moral reasoning and guides ethical decisions.[68] We only wish to show that the interaction with morality varies between cultures and countries. III. A Flexible Ethical Approach The plurality of different moral approaches described above demonstrates that there can be no universally acceptable uniform law for ESC on a global scale. Instead of developing one standard, flexible ethical applications must be continued. We recommend local guidelines that incorporate important cultural and ethical priorities. While the Declaration of Helsinki is more relevant to people in clinical trials receiving ESC products, in keeping with the tradition of protections for research subjects, consent of the donor is an ethical requirement for ESC donation in many jurisdictions including the US, Canada, and Europe.[69] The Declaration of Helsinki provides a reference point for regulatory standards and could potentially be used as a universal baseline for obtaining consent prior to gamete or embryo donation. For instance, in Columbia University’s egg donor program for stem cell research, donors followed standard screening protocols and “underwent counseling sessions that included information as to the purpose of oocyte donation for research, what the oocytes would be used for, the risks and benefits of donation, and process of oocyte stimulation” to ensure transparency for consent.[70] The program helped advance stem cell research and provided clear and safe research methods with paid participants. Though paid participation or covering costs of incidental expenses may not be socially acceptable in every culture or context,[71] and creating embryos for ESC research is illegal in many jurisdictions, Columbia’s program was effective because of the clear and honest communications with donors, IRBs, and related stakeholders. This example demonstrates that cultural acceptance of scientific research and of the idea that an egg or embryo does not have personhood is likely behind societal acceptance of donating eggs for ESC research. As noted, many countries do not permit the creation of embryos for research. Proper communication and education regarding the process and purpose of stem cell research may bolster comprehension and garner more acceptance. “Given the sensitive subject material, a complete consent process can support voluntary participation through trust, understanding, and ethical norms from the cultures and morals participants value. This can be hard for researchers entering countries of different socioeconomic stability, with different languages and different societal values.[72] An adequate moral foundation in medical ethics is derived from the cultural and religious basis that informs knowledge and actions.[73] Understanding local cultural and religious values and their impact on research could help researchers develop humility and promote inclusion. IV. Concerns Some may argue that if researchers all adhere to one ethics standard, protection will be satisfied across all borders, and the global public will trust researchers. However, defining what needs to be protected and how to define such research standards is very specific to the people to which standards are applied. We suggest that applying one uniform guide cannot accurately protect each individual because we all possess our own perceptions and interpretations of social values.[74] Therefore, the issue of not adjusting to the moral pluralism between peoples in applying one standard of ethics can be resolved by building out ethics models that can be adapted to different cultures and religions. Other concerns include medical tourism, which may promote health inequities.[75] Some countries may develop and approve products derived from ESC research before others, compromising research ethics or drug approval processes. There are also concerns about the sale of unauthorized stem cell treatments, for example, those without FDA approval in the United States. Countries with robust research infrastructures may be tempted to attract medical tourists, and some customers will have false hopes based on aggressive publicity of unproven treatments.[76] For example, in China, stem cell clinics can market to foreign clients who are not protected under the regulatory regimes. Companies employ a marketing strategy of “ethically friendly” therapies. Specifically, in the case of Beike, China’s leading stem cell tourism company and sprouting network, ethical oversight of administrators or health bureaus at one site has “the unintended consequence of shifting questionable activities to another node in Beike's diffuse network.”[77] In contrast, Jordan is aware of stem cell research’s potential abuse and its own status as a “health-care hub.” Jordan’s expanded regulations include preserving the interests of individuals in clinical trials and banning private companies from ESC research to preserve transparency and the integrity of research practices.[78] The social priorities of the community are also a concern. The ISSCR explicitly states that guidelines “should be periodically revised to accommodate scientific advances, new challenges, and evolving social priorities.”[79] The adaptable ethics model extends this consideration further by addressing whether research is warranted given the varying degrees of socioeconomic conditions, political stability, and healthcare accessibilities and limitations. An ethical approach would require discussion about resource allocation and appropriate distribution of funds.[80] CONCLUSION While some religions emphasize the sanctity of life from conception, which may lead to public opposition to ESC research, others encourage ESC research due to its potential for healing and alleviating human pain. Many countries have special regulations that balance local views on embryonic personhood, the benefits of research as individual or societal goods, and the protection of human research subjects. To foster understanding and constructive dialogue, global policy frameworks should prioritize the protection of universal human rights, transparency, and informed consent. In addition to these foundational global policies, we recommend tailoring local guidelines to reflect the diverse cultural and religious perspectives of the populations they govern. Ethics models should be adapted to local populations to effectively establish research protections, growth, and possibilities of stem cell research. For example, in countries with strong beliefs in the moral sanctity of embryos or heavy religious restrictions, an adaptive model can allow for discussion instead of immediate rejection. In countries with limited individual rights and voice in science policy, an adaptive model ensures cultural, moral, and religious views are taken into consideration, thereby building social inclusion. While this ethical consideration by the government may not give a complete voice to every individual, it will help balance policies and maintain the diverse perspectives of those it affects. Embracing an adaptive ethics model of ESC research promotes open-minded dialogue and respect for the importance of human belief and tradition. By actively engaging with cultural and religious values, researchers can better handle disagreements and promote ethical research practices that benefit each society. This brief exploration of the religious and cultural differences that impact ESC research reveals the nuances of relative ethics and highlights a need for local policymakers to apply a more intense adaptive model. - [1] Poliwoda, S., Noor, N., Downs, E., Schaaf, A., Cantwell, A., Ganti, L., Kaye, A. D., Mosel, L. I., Carroll, C. B., Viswanath, O., & Urits, I. (2022). Stem cells: a comprehensive review of origins and emerging clinical roles in medical practice. 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Accountability in research, 13(1), 101–109. https://doi.org/10.1080/08989620600634193. [35] Alahmad, G., Aljohani, S., & Najjar, M. F. (2020). Ethical challenges regarding the use of stem cells: interviews with researchers from Saudi Arabia. BMC medical ethics, 21(1), 35. https://doi.org/10.1186/s12910-020-00482-6 [36]Association for the Advancement of Blood and Biotherapies. https://www.aabb.org/regulatory-and-advocacy/regulatory-affairs/regulatory-for-cellular-therapies/international-competent-authorities/saudi-arabia [37] Alahmad, G., Aljohani, S., & Najjar, M. F. (2020). Ethical challenges regarding the use of stem cells: Interviews with researchers from Saudi Arabia. BMC medical ethics, 21(1), 35. https://doi.org/10.1186/s12910-020-00482-6 [38] Alahmad, G., Aljohani, S., & Najjar, M. F. (2020). Ethical challenges regarding the use of stem cells: Interviews with researchers from Saudi Arabia. BMC medical ethics, 21(1), 35. https://doi.org/10.1186/s12910-020-00482-6 Culturally, autonomy practices follow a relational autonomy approach based on a paternalistic deontological health care model. The adherence to strict international research policies and religious pillars within the regulatory environment is a great foundation for research ethics. However, there is a need to develop locally targeted ethics approaches for research (as called for in Alahmad, G., Aljohani, S., & Najjar, M. F. (2020). Ethical challenges regarding the use of stem cells: interviews with researchers from Saudi Arabia. BMC medical ethics, 21(1), 35. https://doi.org/10.1186/s12910-020-00482-6), this decision-making approach may help advise a research decision model. For more on the clinical cultural autonomy approaches, see: Alabdullah, Y. Y., Alzaid, E., Alsaad, S., Alamri, T., Alolayan, S. W., Bah, S., & Aljoudi, A. S. (2022). Autonomy and paternalism in Shared decision‐making in a Saudi Arabian tertiary hospital: A cross‐sectional study. Developing World Bioethics, 23(3), 260–268. https://doi.org/10.1111/dewb.12355; Bukhari, A. A. (2017). Universal Principles of Bioethics and Patient Rights in Saudi Arabia (Doctoral dissertation, Duquesne University). https://dsc.duq.edu/etd/124; Ladha, S., Nakshawani, S. A., Alzaidy, A., & Tarab, B. (2023, October 26). Islam and Bioethics: What We All Need to Know. Columbia University School of Professional Studies. https://sps.columbia.edu/events/islam-and-bioethics-what-we-all-need-know [39] Ababneh, M. A., Al-Azzam, S. I., Alzoubi, K., Rababa’h, A., & Al Demour, S. (2021). Understanding and attitudes of the Jordanian public about clinical research ethics. Research Ethics, 17(2), 228-241. https://doi.org/10.1177/1747016120966779 [40] Ababneh, M. A., Al-Azzam, S. I., Alzoubi, K., Rababa’h, A., & Al Demour, S. (2021). Understanding and attitudes of the Jordanian public about clinical research ethics. Research Ethics, 17(2), 228-241. https://doi.org/10.1177/1747016120966779 [41] Dajani, R. (2014). Jordan’s stem-cell law can guide the Middle East. Nature 510, 189. https://doi.org/10.1038/510189a [42] Dajani, R. (2014). Jordan’s stem-cell law can guide the Middle East. Nature 510, 189. https://doi.org/10.1038/510189a [43] The EU’s definition of autonomy relates to the capacity for creating ideas, moral insight, decisions, and actions without constraint, personal responsibility, and informed consent. However, the EU views autonomy as not completely able to protect individuals and depends on other principles, such as dignity, which “expresses the intrinsic worth and fundamental equality of all human beings.” Rendtorff, J.D., Kemp, P. (2019). Four Ethical Principles in European Bioethics and Biolaw: Autonomy, Dignity, Integrity and Vulnerability. In: Valdés, E., Lecaros, J. (eds) Biolaw and Policy in the Twenty-First Century. International Library of Ethics, Law, and the New Medicine, vol 78. Springer, Cham. https://doi.org/10.1007/978-3-030-05903-3_3 [44] Council of Europe. Convention for the protection of Human Rights and Dignity of the Human Being with regard to the Application of Biology and Medicine: Convention on Human Rights and Biomedicine (ETS No. 164) https://www.coe.int/en/web/conventions/full-list?module=treaty-detail&treatynum=164 (forbidding the creation of embryos for research purposes only, and suggests embryos in vitro have protections.); Also see Drabiak-Syed B. K. (2013). New President, New Human Embryonic Stem Cell Research Policy: Comparative International Perspectives and Embryonic Stem Cell Research Laws in France. Biotechnology Law Report, 32(6), 349–356. https://doi.org/10.1089/blr.2013.9865 [45] Rendtorff, J.D., Kemp, P. (2019). Four Ethical Principles in European Bioethics and Biolaw: Autonomy, Dignity, Integrity and Vulnerability. In: Valdés, E., Lecaros, J. (eds) Biolaw and Policy in the Twenty-First Century. International Library of Ethics, Law, and the New Medicine, vol 78. Springer, Cham. https://doi.org/10.1007/978-3-030-05903-3_3 [46] Tomuschat, C., Currie, D. P., Kommers, D. P., & Kerr, R. (Trans.). (1949, May 23). Basic law for the Federal Republic of Germany. https://www.btg-bestellservice.de/pdf/80201000.pdf [47] Regulation of Stem Cell Research in Germany. Eurostemcell. (2017, April 26). https://www.eurostemcell.org/regulation-stem-cell-research-germany [48] Regulation of Stem Cell Research in Finland. Eurostemcell. (2017, April 26). https://www.eurostemcell.org/regulation-stem-cell-research-finland [49] Regulation of Stem Cell Research in Spain. Eurostemcell. (2017, April 26). https://www.eurostemcell.org/regulation-stem-cell-research-spain [50] Some sources to consider regarding ethics models or regulatory oversights of other cultures not covered: Kara MA. Applicability of the principle of respect for autonomy: the perspective of Turkey. J Med Ethics. 2007 Nov;33(11):627-30. doi: 10.1136/jme.2006.017400. PMID: 17971462; PMCID: PMC2598110. Ugarte, O. N., & Acioly, M. A. (2014). The principle of autonomy in Brazil: one needs to discuss it ... Revista do Colegio Brasileiro de Cirurgioes, 41(5), 374–377. https://doi.org/10.1590/0100-69912014005013 Bharadwaj, A., & Glasner, P. E. (2012). Local cells, global science: The rise of embryonic stem cell research in India. Routledge. For further research on specific European countries regarding ethical and regulatory framework, we recommend this database: Regulation of Stem Cell Research in Europe. Eurostemcell. (2017, April 26). https://www.eurostemcell.org/regulation-stem-cell-research-europe [51] Klitzman, R. (2006). Complications of culture in obtaining informed consent. The American Journal of Bioethics, 6(1), 20–21. https://doi.org/10.1080/15265160500394671 see also: Ekmekci, P. E., & Arda, B. (2017). Interculturalism and Informed Consent: Respecting Cultural Differences without Breaching Human Rights. Cultura (Iasi, Romania), 14(2), 159–172.; For why trust is important in research, see also: Gray, B., Hilder, J., Macdonald, L., Tester, R., Dowell, A., & Stubbe, M. (2017). Are research ethics guidelines culturally competent? Research Ethics, 13(1), 23-41. https://doi.org/10.1177/1747016116650235 [52] The Qur'an (M. Khattab, Trans.). (1965). Al-Mu’minun, 23: 12-14. https://quran.com/23 [53] Lenfest, Y. (2017, December 8). Islam and the beginning of human life. Bill of Health. https://blog.petrieflom.law.harvard.edu/2017/12/08/islam-and-the-beginning-of-human-life/ [54] Aksoy, S. (2005). Making regulations and drawing up legislation in Islamic countries under conditions of uncertainty, with special reference to embryonic stem cell research. Journal of Medical Ethics, 31:399-403.; see also: Mahmoud, Azza. "Islamic Bioethics: National Regulations and Guidelines of Human Stem Cell Research in the Muslim World." Master's thesis, Chapman University, 2022. https://doi.org/10.36837/ chapman.000386 [55] Rashid, R. (2022). When does Ensoulment occur in the Human Foetus. Journal of the British Islamic Medical Association, 12(4). ISSN 2634 8071. https://www.jbima.com/wp-content/uploads/2023/01/2-Ethics-3_-Ensoulment_Rafaqat.pdf. [56] Sivaraman, M. & Noor, S. (2017). Ethics of embryonic stem cell research according to Buddhist, Hindu, Catholic, and Islamic religions: perspective from Malaysia. Asian Biomedicine,8(1) 43-52. https://doi.org/10.5372/1905-7415.0801.260 [57] Jafari, M., Elahi, F., Ozyurt, S. & Wrigley, T. (2007). 4. Religious Perspectives on Embryonic Stem Cell Research. In K. Monroe, R. Miller & J. Tobis (Ed.), Fundamentals of the Stem Cell Debate: The Scientific, Religious, Ethical, and Political Issues (pp. 79-94). Berkeley: University of California Press. https://escholarship.org/content/qt9rj0k7s3/qt9rj0k7s3_noSplash_f9aca2e02c3777c7fb76ea768ba458f0.pdf https://doi.org/10.1525/9780520940994-005 [58] Lecso, P. A. (1991). The Bodhisattva Ideal and Organ Transplantation. Journal of Religion and Health, 30(1), 35–41. http://www.jstor.org/stable/27510629; Bodhisattva, S. (n.d.). The Key of Becoming a Bodhisattva. A Guide to the Bodhisattva Way of Life. http://www.buddhism.org/Sutras/2/BodhisattvaWay.htm [59] There is no explicit religious reference to when life begins or how to conduct research that interacts with the concept of life. However, these are relevant verses pertaining to how the fetus is viewed. ((King James Bible. (1999). Oxford University Press. (original work published 1769)) Jerimiah 1: 5 “Before I formed thee in the belly I knew thee; and before thou camest forth out of the womb I sanctified thee…” In prophet Jerimiah’s insight, God set him apart as a person known before childbirth, a theme carried within the Psalm of David. Psalm 139: 13-14 “…Thou hast covered me in my mother's womb. I will praise thee; for I am fearfully and wonderfully made…” These verses demonstrate David’s respect for God as an entity that would know of all man’s thoughts and doings even before birth. [60] It should be noted that abortion is not supported as well. [61] The Vatican. (1987, February 22). Instruction on Respect for Human Life in Its Origin and on the Dignity of Procreation Replies to Certain Questions of the Day. Congregation For the Doctrine of the Faith. https://www.vatican.va/roman_curia/congregations/cfaith/documents/rc_con_cfaith_doc_19870222_respect-for-human-life_en.html [62] The Vatican. (2000, August 25). Declaration On the Production and the Scientific and Therapeutic Use of Human Embryonic Stem Cells. Pontifical Academy for Life. https://www.vatican.va/roman_curia/pontifical_academies/acdlife/documents/rc_pa_acdlife_doc_20000824_cellule-staminali_en.html; Ohara, N. (2003). Ethical Consideration of Experimentation Using Living Human Embryos: The Catholic Church’s Position on Human Embryonic Stem Cell Research and Human Cloning. Department of Obstetrics and Gynecology. Retrieved from https://article.imrpress.com/journal/CEOG/30/2-3/pii/2003018/77-81.pdf. [63] Smith, G. A. (2022, May 23). Like Americans overall, Catholics vary in their abortion views, with regular mass attenders most opposed. Pew Research Center. https://www.pewresearch.org/short-reads/2022/05/23/like-americans-overall-catholics-vary-in-their-abortion-views-with-regular-mass-attenders-most-opposed/ [64] Rosner, F., & Reichman, E. (2002). Embryonic stem cell research in Jewish law. Journal of halacha and contemporary society, (43), 49–68.; Jafari, M., Elahi, F., Ozyurt, S. & Wrigley, T. (2007). 4. Religious Perspectives on Embryonic Stem Cell Research. In K. Monroe, R. Miller & J. Tobis (Ed.), Fundamentals of the Stem Cell Debate: The Scientific, Religious, Ethical, and Political Issues (pp. 79-94). Berkeley: University of California Press. https://escholarship.org/content/qt9rj0k7s3/qt9rj0k7s3_noSplash_f9aca2e02c3777c7fb76ea768ba458f0.pdf https://doi.org/10.1525/9780520940994-005 [65] Schenker J. G. (2008). The beginning of human life: status of embryo. Perspectives in Halakha (Jewish Religious Law). Journal of assisted reproduction and genetics, 25(6), 271–276. https://doi.org/10.1007/s10815-008-9221-6 [66] Ruttenberg, D. (2020, May 5). The Torah of Abortion Justice (annotated source sheet). Sefaria. https://www.sefaria.org/sheets/234926.7?lang=bi&with=all&lang2=en [67] Jafari, M., Elahi, F., Ozyurt, S. & Wrigley, T. (2007). 4. Religious Perspectives on Embryonic Stem Cell Research. In K. Monroe, R. Miller & J. Tobis (Ed.), Fundamentals of the Stem Cell Debate: The Scientific, Religious, Ethical, and Political Issues (pp. 79-94). Berkeley: University of California Press. https://escholarship.org/content/qt9rj0k7s3/qt9rj0k7s3_noSplash_f9aca2e02c3777c7fb76ea768ba458f0.pdf https://doi.org/10.1525/9780520940994-005 [68] Gert, B. (2007). Common morality: Deciding what to do. Oxford Univ. Press. [69] World Medical Association (2013). World Medical Association Declaration of Helsinki: ethical principles for medical research involving human subjects. JAMA, 310(20), 2191–2194. https://doi.org/10.1001/jama.2013.281053 Declaration of Helsinki – WMA – The World Medical Association.; see also: National Commission for the Protection of Human Subjects of Biomedical and Behavioral Research. (1979). The Belmont report: Ethical principles and guidelines for the protection of human subjects of research. U.S. Department of Health and Human Services. https://www.hhs.gov/ohrp/regulations-and-policy/belmont-report/read-the-belmont-report/index.html [70] Zakarin Safier, L., Gumer, A., Kline, M., Egli, D., & Sauer, M. V. (2018). Compensating human subjects providing oocytes for stem cell research: 9-year experience and outcomes. Journal of assisted reproduction and genetics, 35(7), 1219–1225. https://doi.org/10.1007/s10815-018-1171-z https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6063839/ see also: Riordan, N. H., & Paz Rodríguez, J. (2021). Addressing concerns regarding associated costs, transparency, and integrity of research in recent stem cell trial. Stem Cells Translational Medicine, 10(12), 1715–1716. https://doi.org/10.1002/sctm.21-0234 [71] Klitzman, R., & Sauer, M. V. (2009). Payment of egg donors in stem cell research in the USA. Reproductive biomedicine online, 18(5), 603–608. https://doi.org/10.1016/s1472-6483(10)60002-8 [72] Krosin, M. T., Klitzman, R., Levin, B., Cheng, J., & Ranney, M. L. (2006). Problems in comprehension of informed consent in rural and peri-urban Mali, West Africa. Clinical trials (London, England), 3(3), 306–313. https://doi.org/10.1191/1740774506cn150oa [73] Veatch, Robert M. Hippocratic, Religious, and Secular Medical Ethics: The Points of Conflict. Georgetown University Press, 2012. [74] Msoroka, M. S., & Amundsen, D. (2018). One size fits not quite all: Universal research ethics with diversity. Research Ethics, 14(3), 1-17. https://doi.org/10.1177/1747016117739939 [75] Pirzada, N. (2022). The Expansion of Turkey’s Medical Tourism Industry. Voices in Bioethics, 8. https://doi.org/10.52214/vib.v8i.9894 [76] Stem Cell Tourism: False Hope for Real Money. Harvard Stem Cell Institute (HSCI). (2023). https://hsci.harvard.edu/stem-cell-tourism, See also: Bissassar, M. (2017). Transnational Stem Cell Tourism: An ethical analysis. Voices in Bioethics, 3. https://doi.org/10.7916/vib.v3i.6027 [77]Song, P. (2011) The proliferation of stem cell therapies in post-Mao China: problematizing ethical regulation, New Genetics and Society, 30:2, 141-153, DOI: 10.1080/14636778.2011.574375 [78] Dajani, R. (2014). Jordan’s stem-cell law can guide the Middle East. Nature 510, 189. https://doi.org/10.1038/510189a [79] International Society for Stem Cell Research. (2024). Standards in stem cell research. International Society for Stem Cell Research. https://www.isscr.org/guidelines/5-standards-in-stem-cell-research [80] Benjamin, R. (2013). People’s science bodies and rights on the Stem Cell Frontier. Stanford University Press.

Abstract This paper is one in a series written to lay the groundwork for a book which has the working title ‘Balaam’s Ass: Vernacular Theology in Medieval England’. In particular, it forms half of a diptych of papers whose joint theme is the theological meanings of the vernacular; the other is ‘Visions of lnclusion: Universal Salvation in Pre Reformation England’, Journal of Medieval and Early Modern Studies 27 (1997), 145-87. Other papers whose concerns overlap with this one are The English Mystics’, in David Wallace (ed.), The Cambridge History of Medieval English Literature: Writing in Britain, Io66-I547 (Cambridge, forthcoming); and ‘Censorship and Cultural Change in Late-Medieval England: Vernacular Theology, the Oxford Translation Debate, and Arundel’s Constitutions of 1409’, Speculum, 70 (1995), 822-64. Early versions of parts of the paper were read at ‘The Cultural Work of Ritual, Symbol, and the Other’, University of Western Ontario (London, Ontario, Canada) in February 1995; at ‘Women in the Christian Tradition’, European Science Foundation Conference (Strasbourg, France), October 1995; and to the medieval seminar at Berkeley, California, in March 1996.