Littérature scientifique sur le sujet « SYNTHESIS, BIOMATERIAL, PEPTIDE, CARBOHYDRATE »

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Articles de revues sur le sujet "SYNTHESIS, BIOMATERIAL, PEPTIDE, CARBOHYDRATE"

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Wartchow, Charles A., Peng Wang, Mark D. Bednarski, and Matthew R. Callstrom. "Carbohydrate Protease Conjugates: Stabilized Proteases for Peptide Synthesis." Journal of Organic Chemistry 60, no. 7 (1995): 2216–26. http://dx.doi.org/10.1021/jo00112a049.

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Hossain, Farzana, Shruthi Kandalai, Xiaozhuang Zhou, Nan Zhang, and Qingfei Zheng. "Chemical and Synthetic Biology Approaches for Cancer Vaccine Development." Molecules 27, no. 20 (2022): 6933. http://dx.doi.org/10.3390/molecules27206933.

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Cancer vaccines have been considered promising therapeutic strategies and are often constructed from whole cells, attenuated pathogens, carbohydrates, peptides, nucleic acids, etc. However, the use of whole organisms or pathogens can elicit unwanted immune responses arising from unforeseen reactions to the vaccine components. On the other hand, synthetic vaccines, which contain antigens that are conjugated, often with carrier proteins, can overcome these issues. Therefore, in this review we have highlighted the synthetic approaches and discussed several bioconjugation strategies for developing
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Herzner, Holger, Tanja Reipen, Michael Schultz, and Horst Kunz. "Synthesis of Glycopeptides Containing Carbohydrate and Peptide Recognition Motifs." Chemical Reviews 100, no. 12 (2000): 4495–538. http://dx.doi.org/10.1021/cr990308c.

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Badhe, Ravindra, Pradeep Kumar, Yahya Choonara, et al. "Customized Peptide Biomaterial Synthesis via an Environment-Reliant Auto-Programmer Stigmergic Approach." Materials 11, no. 4 (2018): 609. http://dx.doi.org/10.3390/ma11040609.

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Bini, Davide, Laura Russo, Chiara Battocchio, et al. "Dendron Synthesis and Carbohydrate Immobilization on a Biomaterial Surface by a Double-Click Reaction." Organic Letters 16, no. 5 (2014): 1298–301. http://dx.doi.org/10.1021/ol403476z.

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Matsubara, Teruhiko. "Potential of Peptides as Inhibitors and Mimotopes: Selection of Carbohydrate-Mimetic Peptides from Phage Display Libraries." Journal of Nucleic Acids 2012 (2012): 1–15. http://dx.doi.org/10.1155/2012/740982.

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Glycoconjugates play various roles in biological processes. In particular, oligosaccharides on the surface of animal cells are involved in virus infection and cell-cell communication. Inhibitors of carbohydrate-protein interactions are potential antiviral drugs. Several anti-influenza drugs such as oseltamivir and zanamivir are derivatives of sialic acid, which inhibits neuraminidase. However, it is very difficult to prepare a diverse range of sugar derivatives by chemical synthesis or by the isolation of natural products. In addition, the pathogenic capsular polysaccharides of bacteria are ca
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Racheva, M., O. Romero, K. K. Julich-Gruner, A. S. Ulrich, C. Wischke, and A. Lendlein. "Purity of mushroom tyrosinase as a biocatalyst for biomaterial synthesis affects the stability of therapeutic peptides." MRS Proceedings 1718 (2015): 85–90. http://dx.doi.org/10.1557/opl.2015.260.

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ABSTRACTThe formation of injectable implants in the presence of cells or solutes has previously been conceptualized to be based on the selectivity of bioorthogonal chemical reactions. As an alternative approach, hydrogel network synthesis by enzymatic reactions with a typically high inherent substrate specificity and low toxicity have been repeatedly proposed, e.g. using commercial mushroom tyrosinase (MTyr), which specifically catalyzes phenol oxidation. In this study, it should be explored whether MTyr is compatible with therapeutic peptides that may be delivered from such hydrogels in the f
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Zhong, Wei, Mariusz Skwarczynski, Yoshio Fujita, Pavla Simerska, Michael F. Good, and Istvan Toth. "Design and Synthesis of Lipopeptide - Carbohydrate Assembled Multivalent Vaccine Candidates Using Native Chemical Ligation." Australian Journal of Chemistry 62, no. 9 (2009): 993. http://dx.doi.org/10.1071/ch09065.

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Development of a synthetic vaccine against group A streptococcal infection is increasingly paramount due to the induction of autoimmunity by the main virulent factor – M protein. Peptide vaccines, however, are generally poorly immunogenic, necessitating administration with carriers and adjuvants. One of the promising approaches to deliver antigenic peptides is to assemble peptides on a suitable template which directs the attached peptides to form a well defined tertiary structure. For self-adjuvanting human vaccines, the conjugation of immunostimulatory lipids has been demonstrated as a potent
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Fernandes, Rafaella F., Giordano T. Paganoto, and Marcia L. A. Temperini. "Non-traditional intrinsic luminescence from non-conjugated polymer dots: designing a hybrid biomaterial." Polymer Chemistry 12, no. 43 (2021): 6319–28. http://dx.doi.org/10.1039/d1py01104a.

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Herein, an eco-friendly and facile synthesis of nitrogen-containing non-conjugated polymer dots (NCPD) with optimal blue emission is reported from the biopolymer β-glucan with a peptide–polysaccharide linkage (namely NH2-β-glucan).
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Herzner, Holger, Tanja Reipen, Michael Schultz, and Horst Kunz. "ChemInform Abstract: Synthesis of Glycopeptides Containing Carbohydrate and Peptide Recognition Motifs." ChemInform 32, no. 9 (2001): no. http://dx.doi.org/10.1002/chin.200109270.

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Thèses sur le sujet "SYNTHESIS, BIOMATERIAL, PEPTIDE, CARBOHYDRATE"

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SHAIKH, NASRIN ISMAIL. ""Design and synthesis of relevant biomolecules for functionalization of biomaterial in tissue engineering"." Doctoral thesis, Università degli Studi di Milano-Bicocca, 2011. http://hdl.handle.net/10281/19453.

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Carbohydrates, glycoconjugates, and oligosaccharides are critical components of living systems and mediate a vast number of fundamental biological processes from complex cellular operations required to initiate and sustain life, to recognition events that are responsible for autoimmune diseases, organ rejection, and inflammation. This functional diversity is reflected in the diversity of carbohydrate structures. There is an increasing demand for efficient access to oligosaccharides and glycoconjugates to deepen our understanding of glycobiology and to expedite the development of therape
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Wartchow, Charles Aaron. "Carbohydrate protease conjugates (CPC) : stabilized proteases for peptide synthesis /." The Ohio State University, 1993. http://rave.ohiolink.edu/etdc/view?acc_num=osu1487847309050511.

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GABRIELLI, LUCA. "Glycomimetics: design, synthesis and biological activity studies." Doctoral thesis, Università degli Studi di Milano-Bicocca, 2013. http://hdl.handle.net/10281/41953.

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My PhD project has been focused on the design, synthesis and biological activity studies of glicomimetics. During these three years I have been mainly interested in three different arguments (three proteins: API, Akt, CIM6Pr) that I will elucidate in detail in this thesis. Even if the target proteins (enzymes and receptors) are very different, these three arguments have a common element. In all cases, starting from the known mechanistic, structural and biological information of the single protein, I have designed glycomimetics that are potentially able to interact with the target protein. Al
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Vartak, Abhishek R. "Synthesis and Evaluation of Multi-component Immuno-therapeutics Containing Peptide and Carbohydrate-based Antigens." University of Toledo / OhioLINK, 2019. http://rave.ohiolink.edu/etdc/view?acc_num=toledo1560356357892348.

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Voglmeir, Josef. "Expression of Peptide- and Glycopeptide Modifying Glycosyltransferases for Applications in Liquid- and Solid Phase Carbohydrate Synthesis." Thesis, University of Manchester, 2009. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.508597.

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Jiménez-Castells, Carmen 1982. "Capture and identification of carbohydrate-binding proteins by SPR and CREDEX-MS." Doctoral thesis, Universitat Pompeu Fabra, 2010. http://hdl.handle.net/10803/7237.

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Carbohydrate-binding proteins of non-immunological origin -lectins- have been recognized over the last decades as decisive players in numerous biological processes, ranging from cellcell communication, fertilization, pathogen-cell adhesion to metastasis. Consequently, there is an increasing interest in finding powerful and nanosized tools to screen for these molecules and to study their carbohydrate interactions in detail. Here, two complementary approaches are described to characterize lectin-carbohydrate interactions with high sensitivity, low sample consumption, and without the need for sam
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Huang, Shun-Chiang, and 黃舜強. "Synthesis and analysis of self-assembly peptide supramolecular hydrogel biomaterial conjugated with gold nanoparticles." Thesis, 2013. http://ndltd.ncl.edu.tw/handle/34199658716970636965.

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碩士<br>國立交通大學<br>材料科學與工程學系奈米科技碩博士班<br>101<br>Recently, development of hydrogel nanocomposites offered tremendous scope for future biomaterial applications, including bioanalysis, chemical sensing, and drug delivery. Smart combinations of different nanostructured materials supported the development of multifunctional nanomaterials. In this study, synthesizing self-assembly peptide supramolecular hydrogel 2-Naphthylacetic acid- L-Phenylalanine- L-Phenylalanine- L-Cysteine (NapFFC) has been done and conjugated with gold nanoparticles (AuNPs) as a new and potential composite material. Finding stimu
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Chapitres de livres sur le sujet "SYNTHESIS, BIOMATERIAL, PEPTIDE, CARBOHYDRATE"

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Kihlberg, Jan, Mikael Elofsson, and Lourdes A. Salvador. "[11] Direct synthesis of glycosylated amino acids from carbohydrate peracetates and Fmoc amino acids: Solid-phase synthesis of biomedicinally interesting glycopeptides." In Solid-Phase Peptide Synthesis. Elsevier, 1997. http://dx.doi.org/10.1016/s0076-6879(97)89050-7.

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Jones, John. "Residue-specific considerations." In Amino Acid and Peptide Synthesis. Oxford University Press, 2002. http://dx.doi.org/10.1093/hesc/9780199257386.003.0006.

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This chapter highlights a peptide bond formation with the α-amino group of lysine that requires prior blockade of the ε-amino group. It explains that the required differentiation can be achieved by using the fact that the side-chain amino group is the more basic and nucleophilic because there is an electron-withdrawing group next to the α-amino group. It also considers cyclic, branched, and conjugated structures, which involve cyclization, that is, is the attachment of other peptides and the conjugation of carbohydrate or other moieties through specific side-chains. The construction of these a
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Fields, Gregg B., and Janelle L. Lauer-Fields. "Principles and Practice of Solid-Phase Peptide Synthesis." In Synthetic Peptides. Oxford University Press, 2002. http://dx.doi.org/10.1093/oso/9780195132618.003.0006.

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Peptides play key structural and functional roles in biochemistry, pharmacology, and neurobiology, and are important probes for research in enzymology, immunology, and molecular biology. The amino acid building blocks can be among the 20 genetically encoded L-residues, or else unusual ones, and the sequences can be linear, cyclic, or branched. It follows that rapid, efficient, and reliable methodology for the chemical synthesis of these molecules is of utmost interest. A number of synthetic peptides are significant commercial or pharmaceutical products, ranging from the sweet dipeptide L-Asp-L
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Actes de conférences sur le sujet "SYNTHESIS, BIOMATERIAL, PEPTIDE, CARBOHYDRATE"

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Ajisaka, Katsumi, Chikako Ito, and Syuichi Oka. "CHEMOENZYMATIC SYNTHESIS OF SIALYL T-ANTIGEN-LINKED PENTADECA-PEPTIDE AND ITS CHARACTERIZATION." In XXIst International Carbohydrate Symposium 2002. TheScientificWorld Ltd, 2002. http://dx.doi.org/10.1100/tsw.2002.423.

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Kajimoto, Tetsuya, Toru Tanaka, Chihiro Tsuda, Tsuyoshi Miura, Toshiyuki Inazu, and Shuichi Tsuji. "SYNTHESIS OF PEPTIDE MIMICS OF SUGAR NUCLEOTIDES AS THE INHIBITORS OF GLYCOSYLTRANSFERASES." In XXIst International Carbohydrate Symposium 2002. TheScientificWorld Ltd, 2002. http://dx.doi.org/10.1100/tsw.2002.599.

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