Thèses sur le sujet « Stabilità mediale »
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Sun, Ji. « Gangliosides mediate axon-myelin stability and inhibit neurite outgrowth ». Available to US Hopkins community, 2003. http://wwwlib.umi.com/dissertations/dlnow/3080774.
Texte intégralDrahos, Karen Elizabeth. « Sulfatides mediate Disabled-2 membrane localization and stability during platelet aggregation ». Thesis, Virginia Tech, 2009. http://hdl.handle.net/10919/31626.
Texte intégralMaster of Science
Herman, Allison. « RNA-binding proteins mediate anti-inflammatory regulation of vascular disease ». Diss., Temple University Libraries, 2019. http://cdm16002.contentdm.oclc.org/cdm/ref/collection/p245801coll10/id/554883.
Texte intégralPh.D.
This work identifies the Fragile X-related protein (FXR1) as a reciprocal regulator of HuR target transcripts in vascular smooth muscle cells (VSMC). FXR1 was identified as an HuR interacting protein by liquid chromatography-tandem mass spectrometry (LC-MS/MS). The-HuR-FXR1 interaction is abrogated in RNase-treated extracts, indicating that their association is tethered by mRNAs. FXR1 expression is induced in diseased, but not normal arteries. SiRNA knock down of FXR1 increases abundance and stability of inflammatory mRNAs, while overexpression of FXR1 reduces their abundance and stability. RNA-EMSA and RIP demonstrate that FXR1 directly interacts with an ARE and a previously uncharacterized element in the 3’UTR of TNFa. FXR1 expression is increased in VSMC challenged with the anti-inflammatory cytokine IL-19, and FXR1 is required for IL-19 reduction of HuR. This suggests FXR1 is an anti-inflammation responsive, HuR counter-regulatory protein that reduces abundance of pro-inflammatory transcripts. Additionally, we observed significantly increased poly-A-Binding protein (PABP) expression localizing to discrete punctate structures in both vascular smooth muscle (VSMC) and endothelial cells (EC) of the aortic arch of Ldlr-/- mice, as compared to WT controls. EIF2α phosphorylation, requisite for SG formation, was also induced by clotrimazole and oxLDL in these cells. Interestingly, VSMCs pre-treated with anti-inflammatory cytokine IL-19 followed by clotrimazole significantly reduced the formation of SGs and eIF2a phosphorylation, suggesting a relationship between inflammation and SG formation in vascular cells. Reduction of SG component G3BP1 by siRNA knockdown significantly reduced stress granule formation and inflammatory gene abundance in hVSMC. Microtubule inhibitors reduced SG formation in hVSMC. These results support the hypothesis that SG formation in atherosclerosis is driven by inflammation, SG may mediate the cellular response to inflammation, and that anti-inflammatory treatment may lessen atherosclerosis progression and plaque formation by reduction of SGs.
Temple University--Theses
Keshmiri, Armin [Verfasser], et Joachim [Akademischer Betreuer] Grifka. « Stability of capsule closure and postoperative anterior knee pain after medial parapatellar approach in TKA / Armin Keshmiri ; Betreuer : Joachim Grifka ». Regensburg : Universitätsbibliothek Regensburg, 2019. http://d-nb.info/1175625345/34.
Texte intégralKeene, Alex Carl. « Genetic Dissection of the Neural Circuitry Underlying Memory Stability in Drosophila : A Dissertation ». eScholarship@UMMS, 2006. https://escholarship.umassmed.edu/gsbs_diss/253.
Texte intégralLepareur, Nicolas. « VECTORISATIONS ACTIVE ET PASSIVE DE RADIOPHARMACEUTIQUES DU TECHNETIUM-99m ET DU RHENIUM-188 POUR L'IMAGERIE MEDICALE ET LA THERAPIE ». Phd thesis, Université Rennes 1, 2003. http://tel.archives-ouvertes.fr/tel-00128645.
Texte intégralDans la première partie de ce manuscrit, la synthèse de complexes du rhénium et du technétium-99, [M(RPhCS3)2(RPhCS2)] (M = Re, Tc), est décrite. La préparation de radiopharmaceutiques à base de technétium-99m, analogues des composés obtenus à l'échelle pondérale, est également décrite. La stabilité/réactivité de ces complexes a été étudiée, au moyen de réactions d'échange avec d'autres ligands potentiels, et notamment par des dithiocarbamates, ainsi que par spectrophotométrie d'absorption UV-visible et analyse thermogravimétrique.
La réactivité des complexes vis-à-vis des dithiocarbamates conduit à la possibilité du greffage de biomolécules sur le cœur métallique, via le fragment dithiocarbamate. Cette méthode constitue une alternative potentielle aux procédures actuelles utilisant l'approche bifonctionnelle.
Dans la seconde partie de ce manuscrit, la mise au point d'un kit pour le marquage du lipiodol par le rhénium-188 est décrite, à partir du complexe analogue des complexes décrits dans la première partie. L'huile radiomarquée ainsi obtenue est potentiellement utilisable pour le traitement de l'hépatocarcinome. La stabilité in vitro et in vivo du complexe rhénié 188Re-SSS lipiodol et de son analogue technétié 99mTc-SSS lipiodol a été étudiée, ainsi que leur comportement in vivo sur un modèle de porc sain.
Cette étude a permis de montrer la fixation quasi-exclusive du radiopharmaceutique au niveau du foie, ainsi que la stabilité de ce composé. Sa sélectivité pour les tumeurs reste à démontrer avant de passer aux premiers essais chez l'homme.
Krase, Volker. « Stability of municipal solid waste landfills ». Braunschweig : Inst. für Statik, 2008. http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&doc_number=016739347&line_number=0001&func_code=DB_RECORDS&service_type=MEDIA.
Texte intégralSchleer, Matthias. « Flow structure and stability of a turbocharger centrifugal compressor / ». Düsseldorf : VDI-Verl, 2006. http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&doc_number=015054634&line_number=0001&func_code=DB_RECORDS&service_type=MEDIA.
Texte intégralMatiakis, Tilemachos. « Stability and performance of networked control systems with a distributed controller approach / ». München : Hieronymus, 2009. http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&doc_number=018709040&line_number=0001&func_code=DB_RECORDS&service_type=MEDIA.
Texte intégralMohan, Sumitha. « Stability and disturbance compensation using digital control for grid connected voltage source converters / ». Dresden : TUDpress, 2007. http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&doc_number=016239313&line_number=0001&func_code=DB_RECORDS&service_type=MEDIA.
Texte intégralIsaksson, Anders. « Essays on financial liberalisation in developing countries : capital mobility, price stability, and savings / ». Göteborg : Nationalekonomiska institutionen, Handelshögsk, 1997. http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&doc_number=008008121&line_number=0001&func_code=DB_RECORDS&service_type=MEDIA.
Texte intégralJung, Alexander Christian. « Foreign exchange market efficiency and stability of the European Monetary System in consideration of the Swiss franc / ». Chur [u.a.] : Rüegger, 1992. http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&doc_number=002967885&line_number=0001&func_code=DB_RECORDS&service_type=MEDIA.
Texte intégralRist, Armin. « Hydrothermal processes within the active layer above alpine permafrost in steep scree slopes and their influence on slope stability / ». Zürich : Geographisches Institut der Universität Zürich, 2008. http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&doc_number=016771587&line_number=0001&func_code=DB_RECORDS&service_type=MEDIA.
Texte intégralKrümmelbein, Julia. « Influence of various grazing intensities on soil stability and water balance of a steppe soil in Inner Mongolia, P.R. China / ». Kiel : Inst. für Pflanzenernährung und Bodenkunde, 2007. http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&doc_number=016796677&line_number=0001&func_code=DB_RECORDS&service_type=MEDIA.
Texte intégralSchröder, Hinrich. « Die völkerrechtliche Verantwortlichkeit im Zusammenhang mit failed und failing States / ». Baden-Baden : Nomos, 2007. http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&doc_number=015477608&line_number=0001&func_code=DB_RECORDS&service_type=MEDIA.
Texte intégralOsei-Bonsu, Kofi. « Foam-facilitated oil displacement in porous media ». Thesis, University of Manchester, 2017. https://www.research.manchester.ac.uk/portal/en/theses/foamfacilitated-oil-displacement-in-porous-media(f2b2e93b-3a9b-41fa-a841-f81b271e8fad).html.
Texte intégralPANTINI, SARA. « Analysis and modelling of leachate and gas generation at landfill sites focused on mechanically-biologically treated waste ». Doctoral thesis, Università degli Studi di Roma "Tor Vergata", 2013. http://hdl.handle.net/2108/203393.
Texte intégralEsposito, Francesco. « Biomechanical Analysis on Total Knee Replacement patients during Activities of Daily Living : Medial Pivot or Posterior Stabilized design ? » Doctoral thesis, 2019. http://hdl.handle.net/2158/1152927.
Texte intégralVaisica, Jessica Anne. « Mms1 & ; Mms22 Mediate Genome Stability in Saccharomyces cerevisiae ». Thesis, 2012. http://hdl.handle.net/1807/34951.
Texte intégralWu, Ruo-Yan, et 吳若嫣. « Neuromuscular training increased knee stability in individuals with medial knee osteoarthritis ». Thesis, 2015. http://ndltd.ncl.edu.tw/handle/72005738400278014036.
Texte intégral國立陽明大學
物理治療暨輔助科技學系
103
Background: Joint instability is a risk factor for knee osteoarthritis (KOA). The presence of self-reported knee instability is commonly associated with impaired proprioceptive accuracy, poor sensorimotor control, muscle weakness and high laxity that frequently results in biomechanical aberrations during functional activities. Recent studies found that visualized varus thrust which occurred suddenly during the early stance phase of gait in KOA suffers would be a suitable index for knee instability, which may further result in increased joint translation during movement, especially in the mediolateral direction. Exercise is the first-line treatment for KOA. However, the effect of exercise intervention for knee joint arthro-kinematics in individuals with KOA remains unclear. Purpose: To investigate 1) whether varus thrust would be associated with arthrokinematic alterations, as detected by a 3-dimension (3D) motion tracking system; and 2) whether neuromuscular training could improve knee stability and other clinical outcomes in individuals with medial KOA and varus thrust. Methods: We recruited 24 subjects with medial KOA and visualized varus thrust and 12 healthy volunteers matched with age, gender and body mass index (BMI). The KOA group received 6-week neuromuscular training emphasizing specific muscle strengthening and functional re-training. The VICON motion system was used to capture arthrokinematic data including translation, velocity and acceleration of the tibiofemoral joint during level walking. Clinical outcomes including muscle strength, functional performance and pain were also assessed. Multivariate analyses of variance (MANOVA) were used to analyze the differences between subjects with the KOA and healthy control volunteers. Repeated measures MANOVA were used to determine the statistically significant differences between pre and post-test of the KOA group for arthrokinematic data and muscle strength. Improvement in functional performance and pain were analyzed with Paired t test. Level of significance was set at p < 0.05. Results: Subjects with KOA and varus thrust walked with significantly greater and faster mediolateral translation and had weaker hip/knee strength as compared with the matched controls. After 6-week neuromuscular training, these KOA subjects demonstrated significantly decreased mediolateral/posterioanterior translation, better hip/knee strength, and other clinical outcomes. Discussion and conclusion: Through 3D motion tracking, varus thrust in knee OA subjects was found to be associated with increased mediolateral translation and velocity of tibiofemoral joint. Moreover, 6-week neuromuscular training could decrease translations of the tibiofemoral joint to enhance knee stability that was parallel to other clinical outcomes. Clinical relevance: 3D motion tracking was a feasible tool with discriminant validity and clinical responsiveness to detect knee stability. 6-week neuromuscular exercise was beneficial on knee stability and other clinical performance in individuals with medial KOA.
Leddon, Charles. « Contributions of selected muscles to the dynamic stability of the medial aspect of the elbow ». Thesis, 2003. http://hdl.handle.net/1957/30905.
Texte intégralGraduation date: 2004
Leddon, Charles. « Contributions of selected muscles to the dynamic stability of the medial aspect of the elbow ». 2004. http://www.oregonpdf.org.
Texte intégralCorbavia-Perisić, Ana De. « The implications of bank capital requirements for the financial system stability / ». 2007. http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&doc_number=015624652&line_number=0001&func_code=DB_RECORDS&service_type=MEDIA.
Texte intégral