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1

Sané, Babacar. « Ecophysiologie de l'arche (Senilia senilis), approche expérimentale pour une meilleure compréhension de ses traits d'histoires de vie dans l'estuaire inverse du Sine-Saloum ». Electronic Thesis or Diss., Brest, 2024. http://theses-scd.univ-brest.fr/2024/These-2024-SML-Biologie_marine-SANE_Babacar.pdf.

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Dans l’estuaire inverse du Sine-Saloum (Sénégal), l’arche (Senilia senilis) est une espèce de bivalve clé pour les communautés de femmes qui les exploitent depuis des millénaires. Or, le manque d’informations sur sa biologie ne nous permet pas de prédire la réponse de l’espèce aux variations de ses conditions de vie, en particulier dans un contexte de changement global. Pour répondre à cette problématique, trois questions de recherche ont été posées : (1) Quelles sont ses limites de tolérance physiologique à la température et à la salinité ? (2) Quelles sont les variations saisonnières de sa croissance et la phénologie de sa reproduction dans les principaux sites de pêche artisanale du Sine-Saloum ? (3) Comment la saisonnalité du gradient de salinité à l’échelle du delta influence-t-elle son écologie trophique et sa croissance ? Pour répondre à ces questions, une approche intégrative a été mise en œuvre, combinant des expérimentations en laboratoire, in-situ et des protocoles d’échantillonnage saisonnier. Les résultats de cette étude permettent de décrire l’effet majeur des gradients de salinité, pilotés par la mousson, dans la régulation des traits d’histoire de vie des arches du Sine-Saloum. Bien que l’on démontre que l’espèce supporte une large gamme de variations de salinité, comprise entre 12 à 60, et des températures élevées (seuil à 39°C), ses performances de croissance et la phénologie de sa reproduction suivent un schéma saisonnier et une hétérogénéité spatiale étroitement liés aux variations de salinité. Son écologie trophique apparaît également fortement structurée par le cycle saisonnier de mousson, avec des sources de nourriture variant conjointement en fonction de la saison et de la distance à l’embouchure. Ces résultats contribuent à faire progresser notre connaissance de la niche écologique de l’espèce. Ils constituent à ce titre des jalons indispensables pour contribuer à l'élaboration d'approches de modélisation, de l'échelle individuelle à l'échelle de la population. Ce sont des éléments fondamentaux pour soutenir la durabilité de l’activité de pêche artisanale
In the inverse estuary of the Sine-Saloum (Senegal), the bloody cockle (Senilia senilis) is a key bivalve species for the communities of women who have exploited it for thousands of years. Yet very little information is available about its biology. It is therefore impossible to predict the species'response to variations in its living conditions, particularly in the context of global change. To address this issue, three research questions were posed: (1) What are its physiological tolerance limits to temperature and salinity? (2) What are the seasonal variations in its growth and the phenology of its reproduction in the main artisanal fishing sites in the Sine-Saloum ? (3) How does the seasonality of the salinity gradient at estuary scale influence its trophic ecology and growth? To answer these questions, an integrative approach was implemented, combining laboratory and in situ experiments and seasonal sampling protocols Our results highlight the major effect of salinity gradients, driven by the monsoon, in regulating the life-history traits of S. senilis in the Sine-Saloum. Although the species has been shown to tolerate a wide range of salinity variations, from 12 to 60, and high temperatures (threshold at 39°C), its growth performance and reproductive phenology follow a seasonal pattern and spatial heterogeneity closely linked to salinity variations. Its trophic ecology also appears to be strongly structured by the seasonal monsoon cycle, with food sources varying according to season and distance from the estuary’mouth. These results help to advance our knowledge of the species' ecological niche. As such, they are essential milestones for contributing to the development of modelling approaches, from the individual to the population scale. These are fundamental elements in supporting the sustainability of small-scale fishing
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Maculevič, Tomaš. « Стихотворения в прозе» И. С. Тургенева и философские идеи А. Шопенгауэра : созвучия и параллели ». Master's thesis, Lithuanian Academic Libraries Network (LABT), 2011. http://vddb.laba.lt/obj/LT-eLABa-0001:E.02~2011~D_20110714_145103-25204.

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Объектом исследования данной магистерской работы являются "Стихотворения в прозе" Тургенева, иначе именуемые Senilia, и философские идеи А. Шопенгауэра. Цикл Senilia явился итогом долгих философских размышлений Тургенева над вопросами, которые интересовали его на протяжении всего творчества: это проблема поисков смысла жизни, тайна смерти, сущность веры, назначение любви и добра, эстетика красоты, соотношение природы и человека в ней. Проделанный анализ подтверждает, что философские идеи синтезируются в художественном сознании Тургенева в особые образы-понятия (философемы), в которых отражаются представления писателя о мире и человеке (авторская онтология). Итогом исследования является мысль о различии решения онтологических проблем человеческого бытия. Шопенгауэр выстраивает законченную философскую систему, в которой мир предстает проявлением бессмысленной воли. Человек при этом условии априори не имеет возможности стать счастливым, поэтому единственным его выходом является отказ от воли, смерть и уход в небытие. Тургенев же, несмотря на немногочисленные примеры оптимистического настроения в отдельных миниатюрах, в целом не видит никакого выхода перед лицом смерти и в этом смысле его пессимизм оказывается еще более глубоким, чем у Шопенгауэра.
Šio magistro darbo tyrimo objektas - Turgenevo „Eilėraščiai proza“, dar kitaip vadinami „Senilia“, ir A.Šopenhauerio filosofinės įdėjos. Ciklas „Senilia“ – tai ilgų, filosofinių Turgenevo apmąstymų rezultatas apie klausimus, kurie domino jį visu kūrybiniu laikotarpiu:gyvenimo prasmės pieškų problema, mirties paslaptis, tikėjimo esmė, meilės ir gėrio paskirtis, grožio estetika, gamtos ir žmogaus santykis joje. Atlikta išsami analizė patvirtina, kad Turgenevo kūrybinėje sąmonėje filosofinės įdėjos sintezuojasi į ypatingus vaizdus-suvokimus (filosofemas), kuriuose atsispindi rašytojo požiūris į pasaulį ir žmogų (autorinė antologija) .Tyrimo rezultatas-mintis apie žmogiškosios būties antologinių problemų sprendimų skirtumus. Šopenhaueris pristato išbaigtą filosofinę sistemą, kurioje pasaulis pavaizduotas, kaip beprasmės valios išraiška. Esant tokiai aplinkybei a priori žmogus neturi galimybės tapti laimingu, todėl vienintele išeitimi tampa valios atsisakymas, mirtis ir išėjimas į nebūtį. Turgenevas, nežiūrint į nedaugelį optimistinės nuotaikos apraiškų atskirose jo miniatiūrose, iš esmės nemato jokios išeities prieš akistatą su mirtimi, atsižvelgiant į tai, jo pesimizmas atrodo dar gilesnis, nei Šopenhauerio.
The object of researching in this master`s work are prosaic poems written by I.Turgevev - in other way they were called Senilia. The second object of researche are philosophical ideas of A.Schopenhouer. Senilia was written after long philosophical meaning of questions, which troubled Turgenev for the whole creative life: the problem of searching for the purpose of life, the mistery of death, religious truth, the place of goodness and evil in the world, estethic of beauty, relation of human and nature. The researches say that philosophical ideas in creative Turgenev`s thougths are collected to the special conceptions (philosophems), which reflect his notion of the world and a person in it (author`s onthology). As a result we have a meaning about different ways of solving ontological problems of existence. Schopenhouer makes the whole philosophical system, where the world is shown as a quintessense of an irrational will. A man in these conditions cannot be happy, it causes to refuse from will and escape from life. Turgenev, in spite of rare examples of optimistic mood in some miniatures, does not see any way of resisting the death. In this meaning his pessimism is deeper than Schopenhouer`s one.
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Ruel, Camille. « Effect of social factors on caste differentiation in the ant aphaenogaster senilis ». Doctoral thesis, Universitat Autònoma de Barcelona, 2013. http://hdl.handle.net/10803/123205.

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En los insectos sociales, solo uno o pocos individuos de una colonia se aparean y se reproducen. La producción de las reinas reproductoras y de las obreras no-reproductoras resulta de un cambio del desarrollo en el estadio larval que está, generalmente, regulado por factores ambientales. Sería de esperar que las obreras influyeran sobre la producción de ambas casta mediante el control del desarrollo de las larvas. La teoría de la selección de parentesco predice que la reina actual, las obreras y las larvas tienen un creciente interés en la producción de nuevas reinas, sugiriendo potenciales conflictos intracoloniales. Estos conflictos son resueltos, probablemente, señalizando la presencia de una reina apareada. Las feromonas están, por lo general, implicadas en la resolución del conflicto, pero su naturaleza química y sus efectos todavía permanecen difíciles de conocer. La presente tesis tiene objetivo de caracterizar los factores sociales que regulan la diferenciación de la casta en colonias de hormigas. Para ello, hemos investigado los mecanismos comportamentales, fisiológicos y feromonales que influyen sobre la producción de reinas. La hormiga monogínica Aphaenogaster senilis representa un modelo muy útil. En ella, la reina evita la producción de nuevas reinas mediante el uso de feromonas. Sin embargo, si la reina desaparece, algunas reinas sustitutas son producidas, en muy bajo número, a partir de las larvas diploides totipotentes. En conjunto, han confirmado que las obreras y la reina limitan las decisiones reproductivas de las colonia. En el capítulo dos, mostramos que la producción de reinas está correlacionada con el número de obreras. El destino de las larvas depende de la realización, a nivel de grupo, de las tareas de procesado del alimento realizado por las obreras. El tercer y cuarto capítulo confirman que la reina fecundada inhibe por completo el desarrollo de las larvas en reinas. La reina señala su casta y su estado de apareamiento. Los capítulos tres, cuatro y cinco apuntan a los dimetilalcanos, y especialmente a dos dimetilalcanos específicos de la reina, como buenos candidatos para la señal de reina. Estos resultados son una aportación a la considerable cantidad de trabajos que demuestran el importante papel de los hidrocarburos cuticulares en la comunicación reina-obrera. El tercer capítulo se pregunta por la transmisión de las feromonas reales. Hemos demostrado que los huevos puestos por la reina no transmiten las feromonas reales. En el capítulo cuatro investigamos el papel del comportamiento de la reina para mantener su monopolio reproductor. Concluimos que la toma de decisiones colectiva sobre la producción de sexuados es conformada, principalmente, por la presencia y el estado reproductor de un individuo (la reina).
In social insects, only one or a few individuals of a colony mate and reproduce. The production of reproductive queens and non-reproductive workers arises from a developmental switch at the larval stage, and is generally regulated by environmental factors. Workers are expected to influence the production of both caste through the control of larval development. Kin selection theory predicts that the current queen, the workers and the larvae have increasing interest in the production of new queens, suggesting potential intracolonial conflicts. These conflicts are likely resolved by signalling the presence of a mated queen. Pheromones are generally involved in conflict resolution, but their chemical nature and effects are largely elusive. The present thesis aims at characterizing the social factors regulating caste differentiation in ant colonies. We investigated behavioural, physiological and pheromonal mechanisms that influence the production of queens. The monogynous ant Aphaenogaster senilis provides a useful model. The queen prevents the production of new queens by mean of pheromonal communication. However, if she disappears, a few replacement queens are reared from the totipotent diploid larvae. Overall, our results confirmed that the workers and the queen constrain colonial reproductive decisions. In chapter two, we showed that the production of queens correlated with the number of workers. Larval fate depended on the realization of food processing tasks by the workers at the group level. The third and fourth chapters confirmed that the mated queen fully inhibit the development of larvae toward queens. She signals her caste and mating status. Chapters three, four and five pointed at cuticular dimethylalkanes, and especially two queen-specific dimethylalkanes, as good candidates for the queen signal. These results contribute to substantial amount of works showing the important role of cuticular hydrocarbons in queen-worker communication. The third chapter asked for the transmission of the queen pheromones. We showed that queen-laid eggs do not transmit queen primer pheromones. Chapter four investigated the role of queen’s behaviour to maintain their reproductive monopoly. We conclude that collective decision-making over the production of sexuals is mainly shaped by the presence and reproductive state of one individual (the queen).
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Frigo, Paolo <1986&gt. « EX MEMORIA ricordare oggi nella senilità ». Master's Degree Thesis, Università Ca' Foscari Venezia, 2015. http://hdl.handle.net/10579/6156.

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Fornire una introduzione generale sulla memoria e porre il seguente quesito: cosa comporta oggi, da un punto di vista identitario, la perdita di memoria, in particolare della memoria a breve termine? Sarà quindi spiegata la memoria da un punto di vista scientifico-neurologico. Nello svolgimento ci si focalizzerà sulla memoria nell'anziano, sulla perdita della memoria a breve termine, sul ruolo della memoria dell'anziano oggi nella nostra società e non. Riporterò la mia esperienza personale con l'Associazione Pro Senectute e proverò ad argomentare una risposta alla domanda iniziale facendo le considerazioni finali per la conclusione.
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Orrell, Martin William. « Life events in senile dementia ». Thesis, King's College London (University of London), 1994. https://kclpure.kcl.ac.uk/portal/en/theses/life-events-in-senile-dementia(35b7b188-0dfc-4e09-b4cc-b3cf3ce82236).html.

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IVANCIC-RIBOU, CHRISTINE. « Devenir des dements seniles dans un service de long sejour ». Aix-Marseille 2, 1989. http://www.theses.fr/1989AIX20192.

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Chung-a-on, K. O. « Nutrition in senile demential and depression ». Thesis, University of Surrey, 1985. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.370691.

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Lenhart, Nikola. « Überprüfung der Risikofaktoren der postmenopausalen und senilen Osteoporose ». Diss., lmu, 2005. http://nbn-resolving.de/urn:nbn:de:bvb:19-39501.

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Magri, Micheli Patrícia de Fátima. « Avaliação da suspensão de cirurgia de catarata em idosos através de indicadores de qualidade e entrevistas ». Pontifícia Universidade Católica de São Paulo, 2011. https://tede2.pucsp.br/handle/handle/12388.

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Made available in DSpace on 2016-04-27T18:47:08Z (GMT). No. of bitstreams: 1 Micheli Patricia de Fatima Magri.pdf: 1102664 bytes, checksum: 874b54c39950a11c5274ec08e40f2f5b (MD5) Previous issue date: 2011-07-08
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This thesis is based on the theoretical and interdisciplinary issues surrounding eye health in the elderly and the socio-cultural barriers facilitators. The issue focuses on the elderly with visual impairment caused by cataract senile and needs to undergo an outpatient surgical procedure and, for reasons that are investigated here, can not or will delay the procedure. Research of the statements from the elderly, the reasons for the suspension of cataract surgery. The quantitative approach accounts for the collection and presentation of data obtained from documents and databases available, suitable for "translation" numeric (absolute and relative) in the period January to December 2009. The qualitative approach was conducted from interviews with older people who have benefited from cataract surgery. We used a "field journal" to record the situations that involve the suspension of cataract surgeries. We note that the results in the year 2009 had a total of 2,956 surgical schedule. Of these 78% (2306) were performed and 21% (650) were suspended. The clinical causes of hypertension and had the cough causes more prevalent. The rate of recovery varied between 73.2% to 84.7%. Indicators of surgery cancellation between 15.3% to 26.3%. We selected the stories that attracted the most attention by the content set out in its analysis. Seeking a deeper analysis of the data collected, other meanings were revealed regarding the issues considered as problems that caused the suspension of surgery in the lives of individuals and how they were treated in the health services at two levels: municipal and regional health. In assessing what caused the suspension of the surgery and cause the elderly to find that the financial and psychological impacts are most significant to the elderly respondents
Esta dissertação fundamenta-se na perspectiva teórica e interdisciplinar com questões que envolvem a saúde ocular em idosos e os entraves facilitadores sócio-cultural. O problema focaliza os idosos com dificuldade visual causada pela catarata senil e precisa se submeter a um procedimento cirúrgico ambulatorial e, por motivos que são aqui investigados, não conseguem ou protelam o procedimento. Investigam-se, a partir de falas dos idosos, as razões da suspensão de cirurgias de catarata. A abordagem quantitativa responde, pela coleta e apresentação de dados obtidos junto a documentos e bancos de dados disponíveis; passíveis de tradução numérica (absoluta e relativa), no período janeiro a dezembro de 2009. A abordagem qualitativa foi realizada a partir de entrevistas junto a idosos que não se beneficiaram da cirurgia de catarata. Foi utilizado um diário de campo para o registro das situações que, envolvem a suspensão das cirurgias de catarata. Verificamos nos resultados que, no ano de 2009 tivemos um agendamento cirúrgico total de 2.956. Destas 78% (2.306) foram realizadas e 21% (650) foram suspensas. As causas clínicas tiveram a Hipertensão arterial e a tosse as causas mais prevalente. A taxa de aproveitamento cirúrgico variou de 73,2% a 84,7%. Os indicadores de suspensão de cirurgia entre 15,3% a 26,3%. Foram selecionados os relatos que mais chamaram a atenção pelo conteúdo expostos na sua analise. Buscando uma maior profundidade na análise dos dados coletados, outros significados foram revelados relativos às questões consideradas como dificuldades que a suspensão da cirurgia causou nas vidas dos indivíduos e, como foram atendidos nos serviços de saúde nos dois níveis: municipal e regional de saúde. Ao avaliar o que a suspensão da cirurgia causou e causa para os idosos verificamos que os impactos psicológicos e financeiros são os mais significantes aos idosos entrevistados
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TAILLARD, PHILIPPE. « Strategie therapeutique institutionnelle de la demence senile ». Rennes 1, 1992. http://www.theses.fr/1992REN1M096.

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Duban, Ivan. « Analýza vhodných metod ocenění Mestskej plavárne v Senici ». Master's thesis, Vysoké učení technické v Brně. Ústav soudního inženýrství, 2017. http://www.nusl.cz/ntk/nusl-318572.

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The main goal of this thesis is to analyze appropriate methods and approaches that lead to valuation of a sports complex, specifically the public swimming pool complex in Senica before and after reconstruction. The aim is to estimate the expenses that are related to running the place and to analyze its possible revenue. The object´s price is based on the up-to-date valuation acts. To perform the valuation, it was necessary to acquire the corresponding technical and economic documentation. Based on these documents, there is a visible technical upgrade, which is due to a reconstruction. The object is owned and managed by the town of Senica.
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Fournier, Brigitte. « Denutrition, dysimmunite et demence senile de type alzheimer ». Angers, 1991. http://www.theses.fr/1991ANGE1100.

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La, Rosa Giulia. « Per un commento alle Senili di Petrarca : aspetti micro-testuali e macro-strutturali della raccolta ». Electronic Thesis or Diss., Paris 3, 2023. https://theses.hal.science/tel-04619703.

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Cette thèse porte sur le recueil des Res Seniles de Pétrarque, le dernier recueil épistolaire en latin commencé par l’auteur en 1361 et achevé in limine mortis en 1374. Ce travail de recherche se propose d’explorer l’espace macro-structurel des Senili de Pétrarque, en accordant une attention particulière aux paramètres de composition et aux stratégies de connexion interne qui sous-tendent la création du recueil de senilitate. Ma recherche se concentre précisément sur la relation réciproque qui existe entre les textes individuels et la collection conçue pour les accueillir. La thèse se compose de trois parties. La première est structurée en trois chapitres: le premier est consacré à la genèse du recueil des Senili; le deuxième se concentre sur la tradition du texte; le troisième chapitre de la première partie reconstruit l’histoire éditoriale de la syllogue. La section principale de la thèse propose un examen des dix-sept livres des Res Seniles. Pour chaque liber, a été défini une vue synthétique de son contenu, accompagné de données sur la cohérence textuelle, la datation et l’ordre des lettres, le nombre et l’identité des destinataires, et la présence éventuelle de liens intra- et intertextuelles qui permettent de démêler le réseau de renvois à d’autres écrits de Pétrarque.La troisième partie de la thèse rend compte de la solidité de la conception d’ensemble de l’ouvrage, en mettant en évidence la cohérence et la cohésion du macro-texte et en interprétant les logiques organisationnelles qui ont présidé à l’agencement des textes du recueil
This thesis focuses on the collection of Francesco Petrarca’s Res Seniles, the last latin epistolary started by the author in 1361 and concluded in limine mortis in 1374. This thesis intends to delve into the macro-structural space of Petrarca’s Senili, with specific attention toward the compositional parameters and the strategies of internal connection underlying the creation of the collection de senilitate. My research focuses precisely on the reciprocal relationship that exists between the individual texts and the collection designed to accommodate them. The thesis consists of three parts. The first is structured in three chapters; the first one is dedicated to the genesis of the Senili’s collection; the second one focuses on the tradition of the text; the third chapter of the first part reconstructs the editorial history of the sylloge. The main section of the thesis offers an examination of the Res Seniles seventeen books. For each liber, it has been defined a summary prospectus of its contents, accompanied by data on textual consistency, the dating and the ordering of the letters, the number and identity of the addressees, and the possible presence of intra- and intertextual references that allow unraveling the network of cross-references to other Petrarchan writings.The third part of the thesis gives an account of the solidity of the overall design of the work, highlighting the coherence and cohesion of the macro-text and interpreting the organizational logics that presided over the arrangement of the texts in the collection
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Andrews, Emily Stella. « Senility before Alzheimer : old Age in British psychiatry, c. 1835-1912 ». Thesis, University of Warwick, 2014. http://wrap.warwick.ac.uk/65690/.

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This thesis addresses the place of old age in British psychiatry, from 1835-1912. It asks: how were mental disorders in old age understood, categorised and responded to? It seeks answers to these questions in three sets of sources: theoretical published works written by professional psychiatrists, the official reports of the bodies charged with managing the asylum at a national and local level, and in the patient records of Hanwell County Lunatic Asylum. It argues that the ‘senile’ became more clearly defined in the latter nineteenth century, in politics and in medicine, as a residual category of person: too insane for the workhouse, too old for the asylum. It shows that, during this period, older people in the asylum were increasingly likely to be viewed as ‘old’. Through the increasing focus on internal pathology as an aetiological determinant of mental disorder, both engendered and reflected in changes to the asylum’s patient records, the inherent agedness of older people – with associations of inevitable decline, incurability and dependency – became central to the way that psychiatrists interpreted their mental disorders. The senile were a controversial group in nineteenth-century psychiatry. The administrators of Lunacy made attempts to exclude them from the asylum, but families and workhouse officials continued to send them there. The asylum played an important role in latter-nineteenth-century London as a pressure-valve for those whose behaviour made them unmanageable in other settings. Without more specialised provision, the asylum was often the only institution which could manage the elderly mentally disordered. Once there, aged patients worked and were cared for alongside the rest of the asylum population, usually until their death.
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Dehm-Gauwerky, Bärbel. « Inszenierungen des Sterbens : innere und äussere Wirklichkeiten im Übergang ; eine psychoanalytische Studie über den Prozeß des Sterbens anhand der musiktherapeutischen Praxis mit altersdementen Menschen / ». Marburg : Tectum-Verl, 2006. http://deposit.ddb.de/cgi-bin/dokserv?id=2790454&prov=M&dok_var=1&dok_ext=htm.

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LEJARD, ERIC. « Incidence de la demence dans la pratique psychiatrique hospitaliere ». Angers, 1989. http://www.theses.fr/1989ANGE1064.

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Netten, Ann Penelope. « Residential care and senile dementia : the effect of the physical and social environment of homes for elderly people on residents suffering from senile dementia ». Thesis, University of Kent, 1989. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.236247.

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Jones, Shirley A. « Tetrahydrobiopterin metabolism in depression and senile dementia of Alzheimer type ». Thesis, Aston University, 1988. http://publications.aston.ac.uk/12519/.

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Excretion of biopterin and the related pteridines neo-pterin and pterin was measured in urine samples from a group of 25 male and 51 female depressed outpatients receiving lithium therapy, and compared to 61 male and female control subjects. The ratio of neopterin to biopterin excreted (N/B) was significantly higher in the patients than controls (p< 0.01), and the significant (p< 0.01) positive correlation between urinary neopterin and biopterin shown by the controls was absent in the patients, indicating disrupted biosynthesis of BH4. Urinary cortisol excretion was similar in all groups, but creatinine excretion was diminished in the patients, suggesting a nephrogenic effect of lithium. Serum folate was shown to correlate with urinary biopterin in female unipolar patients. Two groups of elderly females with senile dementia of Alzheimer type (SDAT) were examined for urinary pteridine excretion. In group I (n= 10), N/B was significantly higher than in 24 controls (p< 0.05) and the ratio B/B+ N significantly lower, indicating diminished tetrahydrobiopterin biosynthesis. A second study on 30 patients and 24 age-matched controls confirmed these findings. However, as N correlated with B in both patients and controls, the alteration in BH4 metabolism in SDAT is possibly different to that shown in depression. Lithium had no effect in vivo or in vitro on wistar rat brain or liver BH4 biosynthesis or salvage enzyme dihydropteridine reductase at a range of concentrations and duration of dosing period. In general, no significant effects were shown by the tricyclic antidepressant imipramine, the anticonvulsant sodium valproate, the vitamin folic acid or the anticholinergic agent methylparatyrosine, indicating that BH_4 may differ in man and rat. The synthetic corticosteroid dexamethasone had no effect on rat brain metabolism, nor did stimulation of natural cortisol by stress-immobilisation, although hypothalamic-pituitary-adrenal axis disturbances are know in depression.
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LAURENT-LASSEGNORE, CHANTAL. « L'etat nutritionnel dans les etats dementiels : etude prospective et controlee sur 45 personnes agees hospitalisees a l'hopital psychiatrique charles perrens ». Bordeaux 2, 1988. http://www.theses.fr/1988BOR25308.

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BARBOLOSI, PIERRE. « Recherche d'une strategie diagnostique dans les etats dementiels ». Aix-Marseille 2, 1989. http://www.theses.fr/1989AIX20404.

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DUCHEMIN, MARIE-HELENE. « Amenagement d'un lieu de vie pour personnes agees valides en perte d'autonomie mentale ». Angers, 1991. http://www.theses.fr/1991ANGE1098.

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Glöckner, Frauke. « Zur Bedeutung der Apolipoproteinexpression für die Entwicklung einer senilen Demenz vom Alzheimer-Typ ». Doctoral thesis, Humboldt-Universität zu Berlin, Medizinische Fakultät - Universitätsklinikum Charité, 2006. http://dx.doi.org/10.18452/15437.

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Der bedeutendste Risikofaktor für die Demenz vom Azheimer Typ (DAT) ist, neben dem Alter, der Besitz des e4-Allels des Lipidtransportmoleküls Apolipoprotein E (APOE, Gen; ApoE, Protein). Neben funktionellen Unterschieden der Isoformen könnte auch die quantitative Verfügbarkeit des Proteins bei der Pathogenese der DAT eine Rolle spielen. Da ApoE als Lipidtransporter insbesondere bei plastischen Umbauprozessen in Gehirn wichtig sein könnte, wurde der Proteingehalt in Bezug auf die Schwere der DAT-assoziierten Veränderungen entsprechend der neuropathologischen Stadieneinteilung nach Braak untersucht. Neben ApoE wurde auch Apolipoprotein D (ApoD) in der Pathogenese der DAT diskutiert. Um herauszufinden, ob es hier eine Beziehung zur Schwere der neuropathologischen Veränderungen und/oder dem APOE-Polymorphismus gibt, wurde auch der ApoD-Gehalt untersucht. Bestimmt wurde der Apolipoproteingehalt in 104 nach Alter, Geschlecht, Braak-Stadium und APOE-Genotyp abgeglichenen Hippokampusproben, da diese Hirnregion im Verlauf einer Demenz früh und nachhaltig betroffen ist. Die Daten zeigen einen Anstieg von ApoE in den frühen Stadien der Erkrankung, in denen neuroplastische Reparationsvorgänge nachweisbar sind, und eine kontinuierliche Zunahme des ApoD-Gehalts mit der Schwere der neurofibrillären Veränderungen in den APOE e3/3-Proben. In den Proben, die das Risikoallel APOE e4 trugen, waren keine statistisch signifikanten Veränderungen nachweisbar.
The most important risk factor for Alzheimer´s disease (AD), besides age, is the inheritance of the e4-allele of the lipid transporting apolipoprotein E (APOE, gen; apoE, protein). Apart from functional differences of the apoE isoforms, the quantitative availability of the protein might be important in AD pathogenesis. As a lipidtransporter, apoE should be relevant especially during plastic response of neuronal structures. Hence, apoE levels were investigated in correlation to the severity of pathological changes as staged according to the neuropathological Braak classification of AD. Besides apoE, apolipoprotein D (apoD) is discussed in AD pathogenesis. To clarify whether there is a correlation to AD related neuropathological changes, apoD levels were also determined. The apolipoproteins were determined in 104 age-, gender-, Braak stage- and APOE genotype-matched samples of hippocampal protein extracts because this brain region is early and enduring affected by the disease. The data show an increase in apoE in the early stages of the disease where plastic remodelling occurs and a continuous increase in apoD with the severity of neurofibrillary changes in the APOE e3/3-group only. No statistically relevant changes were observed in samples carrying the AD-risk allele e4.
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LOUET, BRIGITTE. « La demence senile : sa prise en charge au chs de quimper ». Rennes 1, 1992. http://www.theses.fr/1992REN1M034.

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Prévot, Michel. « Le vieillissement cutane : proposition d'une methode d'evaluation de la xerose senile ». Toulouse 3, 1990. http://www.theses.fr/1990TOU31225.

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Czasch, Stephanie Dominique. « Untersuchungen über das Auftreten seniler Plaques und einer assoziierten Gliazellaktivierung im Gehirn alter Hunde ». [S.l.] : [s.n.], 2001. http://deposit.ddb.de/cgi-bin/dokserv?idn=962833428.

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Schubert, Kerstin. « Intravitreales Triamcinolonacetonid und Photodynamische Therapie (ITAP) zur Behandlung der choroidalen Neovaskularisation bei altersabhängiger Makuladegeneration : 12-Monatsergebnisse einer randomisierten, prospektiven, multicenter Phase III-Studie ». kostenfrei, 2009. http://epub.uni-regensburg.de/14787/.

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Gosselin, Olivier. « Les demences de type alzheimer : theories, modeles etiologiques et etude pharmacologique experimentale ». Nancy 1, 1993. http://www.theses.fr/1993NAN11091.

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DECHATRE, MARIN MARIE-CHRISTINE. « Devenir des personnes agees dementes ». Nantes, 1990. http://www.theses.fr/1990NANT129M.

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DELBOS, BERNARD. « Maladie d'alzheimer : le defi et l'aide ». Toulouse 3, 1988. http://www.theses.fr/1988TOU31040.

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Holt, Vance Edward Troupe III. « Characterization of the Developmentally Regulated Osteoclast Support Potential of In Vitro Medullary Adipocytes ». Case Western Reserve University School of Graduate Studies / OhioLINK, 2013. http://rave.ohiolink.edu/etdc/view?acc_num=case1364400382.

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DRAGUTINI, SIGAUD CATHERINE. « Approche diagnostique des demences dans un service de court sejour en geriatrie ». Aix-Marseille 2, 1990. http://www.theses.fr/1990AIX20310.

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Motay, Paramasiven. « Troubles psychocomportementaux chez les déments âgés : étude dans un service de long séjour ». Université Louis Pasteur (Strasbourg) (1971-2008), 1988. http://www.theses.fr/1988STR1M238.

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LACROIX, MICHEL. « Maladie d'alzheimer et demence senile type alzheimer en institution dans le departement du gers ». Toulouse 3, 1992. http://www.theses.fr/1992TOU31079.

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David, Philippe. « Démences du sujet âgé : données actuelles : études de trente cas cliniques observés en secteurs gériatriques ». Toulouse 3, 1990. http://www.theses.fr/1990TOU31003.

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BUTON, LUCHMUN. « Contribution a l'etude de l'evolution clinique et biologique des patients atteints de syndrome dementiel ». Aix-Marseille 2, 1989. http://www.theses.fr/1989AIX20306.

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DENIS, BERTRAND. « Analyse de l'architecture et du fonctionnement des unites specifiques de l'accueil des dements seniles : a propos de 30 etablissements en france ». Angers, 1991. http://www.theses.fr/1991ANGE1094.

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Fleury, Véronique. « Aspects actuels de la détérioration mentale du sujet âgé ». Montpellier 1, 1988. http://www.theses.fr/1988MON11276.

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Kixmiller, Jeffrey S. « Subtyping patients with Senile Dementia of the Alzheimer type using cluster analysis ». Virtual Press, 1992. http://liblink.bsu.edu/uhtbin/catkey/833474.

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The purpose of this study was to determine if distinct subgroups of patients with Senile Dementia of the Alzheimer Type (SDAT) could be identified using seven scales of the Cognitive Behavior Rating Scale (CBRS). Ward's method of cluster analysis was used to group 104 patients with a probable diagnosis of SDAT into subtypes.The following three clusters were identified: (a) Moderately Impaired, (b) Severely Impaired, and (c) Emotionally Intact which displayed differences in symptom severity. Clusters could be partially defined by the amount of time they had been diagnosed with the disease. Differences in the cluster's configuration of scores had little/no descriptive utility. Subsequent discrimination analyses indicated that patient demographics were not as useful as the CBRS in classification of patients.This study provided evidence for the CBRS's ability to differentially portray SDAT patients' profiles. Results provide partial support for a stage model of SDAT. Implications of existing subgroups in SDAT are discussed as they pertain to patient management issues.
Department of Counseling Psychology and Guidance Services
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39

Bergamin, Marco. « Attività motoria in piscina termale come prevenzione e cura della sarcopenia senile ». Doctoral thesis, Università degli studi di Padova, 2012. http://hdl.handle.net/11577/3422470.

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Background: The development and progression of sarcopenia is a complex and multi-factorial process. A growing body of evidence indicates that physical activity in elderly can slow the loss of skeletal muscle and function. Among exercise modalities, water-based protocols are suggested for subjects in whom a lower joint stress is recommended, however, limited data are available about their actual effects in maintaining muscle mass and physical fitness. The novelty of this paper consists in the comparison of two physical activity protocols performed at the same exercise perceived of exertion of which one group underwent a water-based exercise while the other trained on land-based. Objective: determine the effect of a 24-week structured physical activity protocol carried out in thermal water, in order to improve physical function in a group of healthy elderly and comparing with a land-based protocol exercising with the same rate of perceived exertion (RPE) Methods: 59 subjects were recruited, and randomly allocated to three groups: Aquatic Group (AG), Land Group (LG) and Control Group (CG). During the 6 months, subjects followed a twice-a-week exercise intervention. Exercise intensity was monitored using Borg’s Scale and heart rate. Functional evaluation was performed before (T0) and after the exercise period (T1). Results: Because of healthy reasons or lack of interest in participation, 6 subjects dropped out from the study; the average adherence in the 48 sessions was 81.25%. AG showed a non-statistically significant but positive trend in upper- and lower-body strength. LG increased grip strength by 26.1%. Decreases in isotonic (KEM) and isometric knee extension (KET) strengths have been detected in CG. Sum of right and left Back Scratch test values (BS) tests revealed a significant improvement in AG (25.8%; P < 0.05), while Sit & Reach test (SR) improved in all groups. Time Up & Go (TUG) time resulted reduced in AG (-19.3%; P < 0.01) and LG (-12.6%; P < 0.05). Conclusion: Both land- and water-based activities seemed beneficial in maintaining strength and improve lower-body flexibility; moreover aquatic activity appeared the best activity to enhance dynamic balance and upper-body flexibility.
Lo sviluppo della sarcopenia rappresenta un processo complesso e multifattoriale. Un numero crescente di studi indica che l'attività fisica può rallentare la perdita di massa e di funzione muscolo-scheletrica nel soggetto anziano. Tra le diverse modalità di esercizio, l'attività in acqua è particolarmente consigliata, per il minore stress articolare a cui è sottoposto l'organismo durante questo tipo di attività. Tuttavia, gli studi su soggetti anziani, che osservano gli effetti di un protocollo di attività motoria svolto in acqua, per il mantenimento della massa muscolare e dell'efficienza fisica, sono limitati. SCOPO: determinare l'effetto di un protocollo di esercizio in piscina termale, della durata di 24 settimane, sulle variabili di efficienza fisica, in un gruppo di anziani sani. METODO: sono stati reclutati 59 soggetti (N=29 Maschi, N=30 Femmine, età media = 71.2 anni), assegnati casualmente ai seguenti gruppi: gruppo di attività motoria in acqua (AG), gruppo di attività motoria a secco (LG) e gruppo di controllo (CG). Durante i 6 mesi di attività i soggetti hanno effettuato l'attività prevista dal protocollo con frequenza bisettimanale. L'intensità di esercizio è stata monitorata rilevando la frequenza cardiaca ed utilizzando la scala di Borg. La valutazione funzionale è stata realizzata prima e dopo il protocollo di esercizio. La composizione corporea è stata misurata tramite bioimpedenziometria elettrica, la forza isometrica degli arti superiori utilizzando un dinamometro (handgrip), la forza isotonica degli arti inferiori attraverso il test di estensione degli arti inferiori, sempre tramite un dinamometro. RISULTATI: in AG ed in LG sono stati osservati miglioramenti nel test "8-foot up & go". La forza di prensione dell’arto dominante è migliorata nel gruppo LG. La flessibilità della schiena e degli ischio-crurali è aumentata in tutti i gruppi. Il test “Back scratch” ha rivelato miglioramenti della flessibilità nella spalla sinistra, anche se lievi, solo nel gruppo AG. Per entrambi gli arti inferiori l'espressione della forza di estensione del ginocchio è risultata ridotta nel gruppo di controllo nell'analisi tra gruppi (AG vs. LG vs. CG). CONCLUSIONE: i risultati dello studio suggeriscono che il protocollo di attività fisica applicato al gruppo di soggetti anziani si è dimostrato utile poiché ha migliorato l'equilibrio dinamico e la flessibilità. I valori di forza sembrano mantenersi inalterati in entrambi i gruppi sperimentali, suggerendo che anche l’attività fisica in acqua può essere un utile complemento a quella svolta "a secco" per contrastare il decadimento della forza muscolare che si realizza nel soggetto anziano.
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Cañabate, González Mª del Pilar. « La demencia senil, el Alzheimer y el demente. Nuevas categorías para antiguos significados ». Doctoral thesis, Universitat de Barcelona, 2014. http://hdl.handle.net/10803/285003.

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La senilidad no es un fenómeno nuevo. El cambio es la conceptualización de este estado de pérdida cognitiva como situación morbosa. El deterioro senil aparece, desde hace cuatro décadas, como un concepto nuevo, presente en la mirada médica y, por extensión, en la mirada social. Pero hasta hace unas décadas, la senilidad no era objeto de estudio de la medicina. Actualmente, sin embargo, goza de una gestión técnica, farmacológica y médica y su lugar natural es la clínica. El objetivo de este estudio es descubrir qué «condiciones de posibilidad» se están dando en este momento histórico para que la categoría demencia senil se esté elevando al rango de patología; para que se esté reemplazando la categoría senilidad por la de demencia senil como nuevo concepto, y para que los ancianos seniles se conviertan en enfermos. En definitiva hemos examinado cómo se ha pasado de la senilidad a la construcción de la demencia senil y del anciano demente, explorando la construcción histórica de esta nueva subjetividad vinculada a la vejez. Se ha considerado que el deterioro senil, caracterizado en tanto que síndrome patológico, es una invención que resulta de la estructura axiológica de la sociedad. El esquema de valores que conforman el marco de interacción social en el que nos movemos dificultan un encaje no problemático de la vejez en general y de la demencia en particular. La hipótesis de partida ha sido que la medicalización de la demencia senil legitima la exclusión social de los ancianos.
The aim of the present study was to determine which possibility conditions are currently taking place to uplift the category of senile dementia to the realm pathologies; and to point out why the category senility is being replaced by senile dementia as a new concept, altogether allowing the conversion from elders to patients. Briefly, we have investigated the conceptual transition from senility to senile dementia, and how this term and also the term demented have both been historically constructed, yielding, as a result of this process, a new subjectivity linked to the old age.
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CARTRY, GUILHEM. « Evolution spontanee a 10 ans du trou maculaire senile et de l'oeil adelphe ». Lyon 1, 1992. http://www.theses.fr/1992LYO1M169.

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Henschel, Peter W. (Peter William). « Distress and Causal Attributions Associated with Caring for Family Members with Senile Dementia ». Thesis, University of North Texas, 1993. https://digital.library.unt.edu/ark:/67531/metadc501261/.

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A sample of 22 persons who care for relatives exhibiting initial symptoms of senile dementia were administered paper-and- pencil questionnaires to determine their level of subjective burden and psychological symptomatology. Each participant's attributional style was measured on an internal-external dimension, and their causal attributions regarding their relative's symptomatic behaviors were assessed. Results indicated that attributional style did not predict specific attributions about illness-related behaviors, but the tendency to not blame an afflicted relative for their behavior was predictive of subjective burden and symptoms of depression and anxiety. Subjective burden was found to predict feelings of hostility in caregivers.
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43

Mosquera, Oswaldo Gonzalez. « An Engineering Approach to Understand Senile Coconut Palms as Foundation for Biomimetic Applications ». Thesis, Griffith University, 2015. http://hdl.handle.net/10072/367602.

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The present study “is based not on what we can extract from nature, but on what we can learn from her, to strive innovation inspired by nature” (Benyus, 2002). Specifically, the research that constitutes this thesis aims at understanding, from an engineering perspective, the form-structure-function relationship of one monocot plant species, the coconut palm (Cocos nucifera L). Superior to woody plants (i.e. hardwoods and softwoods), coconut palms are able to withstand extreme conditions (e.g. hurricanes, tornadoes) without significant failure. Previous studies have shown that the internal structure of coconut palm stems significantly differs from hardwoods and softwoods, and even other palm species, likely influencing the mechanical performance of the palm. Yet, there is currently an absence of fundamental knowledge about the underlying principles and effects produced by the form and structure on the mechanical function of the palm (i.e. functional design). The present investigation contributes to partially address this issue by investigating the biomaterial form-structure-function relationship at the integral and macroscopic levels of hierarchical structure.
Thesis (PhD Doctorate)
Doctor of Philosophy (PhD)
Griffith School of Engineering
Science, Environment, Engineering and Technology
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44

Hilder, Lisa. « The emotional and instrumental experiences of caregivers of senile dementia/Alzheimer type patients ». CSUSB ScholarWorks, 1993. https://scholarworks.lib.csusb.edu/etd-project/720.

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JAWAHEER, SAUMTALLY BIBI SEHNAAZ. « L'hypothese nutritionnelle dans la demence senile de type alzheimer (dsta) : essai d'un traitement nutritionnel ». Bordeaux 2, 1988. http://www.theses.fr/1988BOR25359.

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46

Miranda, Martínez Dulce María. « ESTUDIO DOCUMENTAL BIOPSICOSOCIAL DEL TRASTORNO DE DEMENCIA SENIL TIPO ALZHEIMER ». Tesis de Licenciatura, Universidad Autónoma del Estado de México, 2015. http://hdl.handle.net/20.500.11799/65946.

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La metodología de análisis desarrollada a lo largo del estudio fue ubicada en el ámbito de lo descriptivo, permitiendo descubrir los componentes básicos del fenómeno determinado extrayéndolo de un amplio acervo bibliográfico de forma objetiva, replicable y válida, así como en una minuciosa búsqueda de servicios socio-sanitarios en el distrito federal y la ciudad de Toluca relacionados con la enfermedad de Alzheimer, la cual aportó de forma clara, precisa y concreta para la consecución de los objetivos propuestos y la integración de un manual práctico para la ejecución de acciones en el afrontamiento de la enfermedad Alzheimer.
Se realizó un estudio documental cualitativo sustentado por la metodología de análisis de contenido, como procedimiento se codificaron sistemáticamente las unidades de estudio en categorías, describiendo de forma precisa el contenido y se agruparon en temas derivados del eje temático siendo la enfermedad de Alzheimer, dicho procedimiento permitió procesar y organizar los datos con la finalidad de obtener una información más completa y generar un mayor entendimiento del material analizado.
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Fritsche, Lars. « Untersuchungen zu den genetischen Ursachen der altersabhängigen Makuladegeneration (AMD) ». kostenfrei, 2009. http://www.opus-bayern.de/uni-regensburg/volltexte/2009/1392/.

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48

Bischof, Kurt. « Erfolgsbedingungen in der Betreuung Demenzerkrankter eine Untersuchung zu kritischen Erfolgsfaktoren in stationären Pflegeeinrichtungen ». Kassel Kassel Univ. Press, 2006. http://www.upress.uni-kassel.de/publi/abstract.php?3-89958-228-4.

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Dehm-Gauwerky, Bärbel. « Inszenierungen des Sterbens innere und äussere Wirklichkeiten im Übergang ; eine psychoanalytische Studie über den Prozess des Sterbens anhand der musiktherapeutischen Praxis mit altersdementen Menschen ». Marburg Tectum, 2005. http://deposit.ddb.de/cgi-bin/dokserv?id=2790454&prov=M&dok_var=1&dok_ext=htm.

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Marquardt, Gesine. « Kriterienkatalog demenzfreundliche Architektur Möglichkeiten der Unterstüzung der räumlichen Orientierung in stationären Altenpflegeeinrichtungen ». Berlin Logos-Verl, 2006. http://deposit.d-nb.de/cgi-bin/dokserv?id=3018827&prov=M&dok_var=1&dok_ext=htm.

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