Articles de revues : « Salviati family »

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Li, Yunyun, Yunli Tong, Jun Ye, Caijuan Zhang, Bin Li, Suying Hu, Xiaoshan Xue et al. « Genome-Wide Characterization of B-Box Gene Family in Salvia miltiorrhiza ». International Journal of Molecular Sciences 24, n^o 3 (21 janvier 2023) : 2146. http://dx.doi.org/10.3390/ijms24032146.

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B-box (BBX) is a type of zinc finger transcription factor that contains a B-box domain. BBX transcription factors play important roles in plant photomorphogenesis, signal transduction, as well as abiotic and biological stress responses. However, the BBX gene family of Salvia miltiorrhiza has not been systematically investigated to date. For this study, based on the genomic data of Salvia miltiorrhiza, 27 SmBBXs genes were identified and clustered into five evolutionary branches according to phylogenetic analysis. The promoter analysis suggested that SmBBXs may be involved in the regulation of the light responses, hormones, stress signals, and tissue-specific development. Based on the transcriptome data, the expression patterns of SmBBXs under different abiotic stresses and plant hormones were analyzed. The results revealed that the expressions of the SmBBXs genes varied under different conditions and may play essential roles in growth and development. The transient expression analysis implied that SmBBX1, SmBBX4, SmBBX9, SmBBX20, and SmBBX27 were in the nucleus. A transcriptional activation assay showed SmBBX1, SmBBX4, SmBBX20, and SmBBX24 had transactivation activities, while SmBBX27 had none. These results provided a basis for further research on the role of SmBBXs in the development of Salvia miltiorrhiza.

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Popov, Ivan Viktorovich, Vera Vladimirovna Chumakova, Ol'ga Ivanovna Popova et Valeriy Fedorovich Chumakov. « BIOLOGICALLY ACTIVE SUBSTANCES EXHIBITING ANTIOXIDANT ACTIVITY, SOME REPRESENTATIVES OF THE LAMIACEAE FAMILY CULTIVATED IN THE STAVROPOL REGION ». chemistry of plant raw material, n^o 4 (27 décembre 2019) : 163–72. http://dx.doi.org/10.14258/jcprm.2019045200.

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The object of the study was the samples of raw materials of the family Lamiaceae plants created in FSBSI "North Caucasus Federal agricultural research center", using a variety of breeding methods: Salvia Officinalis Leaves (cultivar "Dobrynya"), Origanum Vulgare Herb (cultivar "Karamelka"), Salvia Sclarea Herb (cultivar "Salyut"), Satureja Hortensis Herb (cultivar "Karapuz"), Lophanthus Anisatus Herb (cultivar "Premier"), Hyssopus Officinalis Herb (cultivar "Rozovy flamingo"). As a result of the studies conducted by the method of high-performance liquid chromatography, the component composition of phenolic compounds (flavonoids and phenolcarbonic acids) was established. The quantitative content of essential oil, flavonoids and tannins was determined in the studied objects. In salvia officinalis leaves identified 11 phenolic compounds, 2.72% essential oil, 1.22% flavonoids, 12.20% tannins; in origanum vulgare herb – 9 compounds, 1.80% essential oil, 2.10% flavonoids, 8.64% tannins; in salvia sclarea herb – 11 compounds, 0.45% essential oil, 2.25% flavonoids, 10.51% tannins; in satureja hortensis herb – 11 compounds, 0.68% essential oil, 0.85% flavonoids, 9.37% tannins; in lophanthus anisatus herb – 11 compounds, 2.15% essential oil, 2.06% flavonoids, 8.30% tannins; in hyssopus officinalis herb – 9 compounds, 0.78% essential oil, 0.91% flavonoids, 9.55% tannins. Determination of antioxidant activity, conducted in two ways (amperometric and titrimetric) showed that water-alcohol extraction of plant raw materials of new varieties of representatives of the family Lamiaceae, created and maximally adapted to the conditions of Stavropol region can be the basis for the production of herbal remedies with antioxidant activity.

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SHAKOOR, Abdul, Fang ZHAO, Gul ZAIB, Wuyang LI, Xincan LAN et Somayeh ESFANDANI-BOZCHALOYI. « Morphometric analysis and sequence related amplified polymorphism determine genetic diversity in Salvia species ». Notulae Botanicae Horti Agrobotanici Cluj-Napoca 49, n^o 1 (14 janvier 2021) : 12153. http://dx.doi.org/10.15835/nbha49112153.

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Salvia species is a member of the Lamiaceae family, and it also possesses medicinal and horticulture values. The genetic diversity was assessed through sequence-related amplified polymorphism. To uncover genetic diversity and species characteristics in Salvia species were studied through a combination of morphological and molecular data. One hundred forty-five individuals related to 30 Salvia were collected in 18 provinces. A total of 157 (Number of total loci) (NTL) DNA bands were produced through polymerase chain reaction (PCR) from 30 Salvia species. These bands were produced with the combinations of 10 selective primers. The total number of amplified fragments ranged from 10 to 20. The predicted unbiased heterozygosity (H) varied between 0.11 (Salvia urmiensis) and 0.31 (Salvia limbata). High Shannon’s information index was detected in Salvia limbata. The genetic similarities between 30 species are estimated from 0.46 to 0.91. Clustering results showed two major clusters. According to the SRAP (Sequence-related amplified polymorphism) markers analysis, Salvia hydrangea and Salvia sharifii had the lowest similarity. Salvia bracteata and Salvia suffruticosa were genetically dissimilar to each other. This study also detected a significant signature of isolation by distance. Present results showed that sequence-related amplified polymorphism has the potential to decipher genetic affinity between Salvia species. Current results have implications in biodiversity and conservation programs. Besides this, present results could pave the way for selecting suitable ecotypes for forage and pasture purposes in Iran.

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Maynard, Rebekah C. I., et John M. Ruter. « DNA Content Estimation in the Genus Salvia ». Journal of the American Society for Horticultural Science 147, n^o 3 (mai 2022) : 123–34. http://dx.doi.org/10.21273/jashs05175-21.

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Salvia is a genetically diverse genus in the Lamiaceae family, with hundreds of species distributed globally. With base chromosome numbers ranging from 6 to 19 and ploidy levels ranging from diploid to octoploid, the genus has been proposed to be subdivided based on molecular data rather than morphology. However, little is known about total DNA content across the genus. The DNA content of 141 Salvia genotypes were analyzed using flow cytometry. Samples of Salvia were stained with propidium iodide and compared with the internal standards Pisum sativum ‘Ctirad’ and Solanum lycopersicum ‘Stupické’ to generate estimations of DNA content. Holoploid 2C genome sizes of the analyzed Salvia ranged from 0.63 pg to 6.12 pg. DNA content showed a wide distribution across chromosome number, ploidy, and clade. The wide distribution of DNA content across the genus further indicates the diversity of Salvia and may be useful for future breeding efforts.

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AFFENZELLER, SUSANNE, et GERHARD STEINER. « Catalog of taxa introduced by Luitfried Salvini-Plawen (1939–2014) ». Zootaxa 4337, n^o 1 (17 octobre 2017) : 73. http://dx.doi.org/10.11646/zootaxa.4337.1.3.

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Luitfried Salvini-Plawen was one of the most distinguished researchers for molluscan phylogenetic systematics of the last decades. In his publications he described a total of 193 species: 134 Solenogastres, 34 Caudofoveata, 14 interstitial Gastropoda, one polyplacophoran and the remaining comprising Cnidaria, Priapulida, Kamptozoa, and Echinodermata. In addition, he introduced 47 genus-group names and 54 names for family-level and higher taxa. This catalog comprises lists of all taxon names published by Luitfried Salvini-Plawen. The catalog entries contain taxonomic information, original citations, type localities and type collections. It aims to facilitate further research on these and related taxa.

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Protsenko, Mariya Anatol'yevna, Natal'ya Alekseyevna Mazurkova, Ekaterina Igorevna Filippova, Tat'yana Abdulkhailovna Kukushkina, Irina Evgen'yevna Lobanova, Yuliya Anatol'yevna Pshenichkina et Galina Ivanovna Vysochina. « ANTI-INFLUENZA ACTIVITY OF PLANT EXTRACTS OF THE LAMIACEAE FAMILY ». chemistry of plant raw material, n^o 2 (10 juin 2021) : 181–90. http://dx.doi.org/10.14258/jcprm.2021028744.

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In this work, it was revealed that water and ethanol extracts of the plants Nepeta cataria, Nepeta sibirica, Scutellaria baicalensis, Hyssopus officinalis, Betonica officinalis, and water extracts of Dracocephalum moldavica, Glechoma hederacea, Mentha arvensis, Prunella vulgaris, Melissa officinalis ethanol extracts of Mentha piperita, Mentha crispa, Origanum vulgare, Hyssopus officinalis, Salvia verticillata showed antiviral activity against the influenza virus subtype H5N1. Aqueous extracts of Nepeta cataria and Glechoma hederacea (NI 3.75) showed the highest antiviral effect against the H5N1 subtype. It was revealed the antiviral activity against influenza virus subtype H3N2 of aqueous and ethanol extracts of Scutellaria baicalensis, Mentha piperita, Mentha arvensis, Mentha crispa, aqueous extract of Dracocephalum moldavica and ethanol extracts of Glechoma hederacea, Origanum vulgare, Prunella vulgaris, Hyssopus officinalis, Betonica officinalis, Salvia verticillata. Ethanolic extract of Betonica officinalis (NI 4.25) showed the highest virus neutralizing activity against the H3N2 subtype. It was carried out chemical analysis of the aerial parts of plants of the Lamiaceae family. It was shown that the highest content of flavonols was observed in Dracocephalum nutans (4.47±0.04%), the highest content of tannins was found in Mentha arvensis (17.62 ± 0.78%), and the highest content catechins were found in Nepeta cataria (0.43 ± 0.007%). Thus, plant extracts of the Lamiaceae family are promising sources for further studies to develop new antiviral drugs.

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Ryazanov, Vitaliy, Galimzhan Duskaev et Konstantin Denisenko. « Dose-dependent effect of plants of the Lamiaceae family on the concentration of methane, fatty acids and nitrogen in the ecosystem in vitro ». BIO Web of Conferences 42 (2022) : 01016. http://dx.doi.org/10.1051/bioconf/20224201016.

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Fermentation processes in the rumen of ruminants determine how much final metabolites and their derivatives will be formed, which are necessary for the full development of the organism, the level of productivity, and also affect the level of formation of endogenous substances, namely, greenhouse gas emissions. These criteria lead us to the search for new feed products that improve the metabolic processes of the rumen and the digestive system as a whole, so phyto-substances can serve as an alternative. The article presents the results of in vitro study of the influence of Salviae folia, Scutellaria baicalensis, Oríganum vulgáre on formation of methane, synthesis of volatile fatty acids and nitrogen, as the main indicator parameters of the enzymatic activity of the rumen of ruminants. It was found that when using phyto- substances: Salviae folia and Scutellaria baicalensis, more acetic and propionic acid was formed, Oríganum vulgare in various dosages shifted towards propionic and valeric acid. Formation of a larger amount of microbial protein (P≤0.05) with use of Salviae folia, Scutellaria baicalensis, Oríganum vulgáre in various dosages was established. Methane production decreased with use of Oríganum vulgáre.

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GIL-MANSILLA, ESTHER, ÓSCAR GARCÍA-ÁLVAREZ et VICTORIANO URGORRI. « New Acanthomeniidae (Solenogastres, Cavibelonia) from the abyssal Angola Basin ». Zootaxa 1866, n^o 1 (3 septembre 2008) : 175. http://dx.doi.org/10.11646/zootaxa.1866.1.8.

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Solenogastres are a small class of vermiform Mollusca that present a mantle with calcareous sclerites and a ventral pedal groove. During the expedition Me48/1 DIVA 1, carried out in the abyssal Angola Basin between 5100-5500 m depth, several specimens of Solenogastres were collected. Their study has made possible to describe two new species and a new genus of the family Acanthomeniidae Salvini-Plawen, 1978, whose anatomical features have caused the modification of the family definition.

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Kassatkina, A. P. « New genus (Entokrohnia) and new species of family Tokiokaispadellidae Salvini-Plaven, 1986 (Сhaetognatha) from south-west Pacific Ocean ». Zoosystematica Rossica 21, n^o 2 (25 décembre 2012) : 318–22. http://dx.doi.org/10.31610/zsr/2012.21.2.318.

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A detailed description and figures of a new species Entokrohnia entiptera sp. nov. are presented. Diagnoses of the families Protoeukrohniidae fam. nov. and Tokiokaispadellidae Salvini-Plaven, 1986, and all the three genera of the latter family: Tokiokaispadella Kassatkina, 1980, Aberrospadella Kassatkina 1971, and Entokrohnia gen. nov. are given.

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Afonso, Andrea F., Olívia R. Pereira et Susana M. Cardoso. « Salvia Species as Nutraceuticals : Focus on Antioxidant, Antidiabetic and Anti-Obesity Properties ». Applied Sciences 11, n^o 20 (9 octobre 2021) : 9365. http://dx.doi.org/10.3390/app11209365.

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Salvia plants belong to the Lamiaceae family and are recognized as being strongly aromatic, being widely used for different purposes in culinary or traditional medicine. These plants are well recognized as being rich in phenolic acids, flavonoids and terpenic compounds, which exhibit health-beneficial activities, protecting against oxidative and inflammatory-related diseases, such as diabetes and obesity. Because of these properties, phytochemicals from Salvia species have been investigated as health promoting agents, for application in distinct fields. However, the growing demand for natural products with possible uses and applications in industry requires scientific validation studies. This review consists of a compilation of relevant studies with an emphasis on the antioxidant, antidiabetic and anti-obesity properties of phenolic-rich extracts from Salvia plants.

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Cherednichenko, Mikhail Yur, Oksana B. Polivanova, Daria An Khlebnikova, Anastasiya Vl Sosina, Mariia M. Belova et Elena An Kalashnikova. « Gene Engineering of Lamiaceae Family : Basic and Applied Research ». Revista Gestão Inovação e Tecnologias 11, n^o 2 (4 juin 2021) : 123–39. http://dx.doi.org/10.47059/revistageintec.v11i2.1648.

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Gene engineering is a convenient way of solving basic and applied tasks related to the system of secondary metabolism of medicinal and aromatic plants, such as a large and economically important plant family Lamiaceae Martinov (Labiatae Juss.) that includes such major species, as Agastache, Dracocephalum, Lavandula, Mentha, Ocimum, Salvia, Satureja, Thymus, etc. The basic value of this method consists in studying the genetic mechanism of secondary metabolism, which includes key enzyme genes, transcription factors, etc. Applied research consists in producing valuable secondary metabolites with biological activity, including active pharmaceutical ingredients in both, the familyʹs plants proper and the heterologous systems using relevant plant genes. This overview considers a set of diverse gene engineering studies.

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Ivanov, Dimitry L., Nina T. Mikkelsen et Christoffer Schander. « Falcidens sagittiferus Salvini-Plawen, 1968 : additional data on ». Fauna norvegica 29 (26 janvier 2010) : 3. http://dx.doi.org/10.5324/fn.v29i0.610.

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Ivanov DL, Mikkelsen NT, Schander C. 2009. Falcidens sagittiferus Salvini-Plawen, 1968: additional data on morphology and distribution (Mollusca, Aplacophora, Caudofoveata). Fauna Norvegica vol 29: 3-9. Falcidens sagittiferus Salvini-Plawen, 1968 is a species of caudofoveate (Chaetodermomorpha) not uncommon in southern Scandinavia. Previous descriptions have however been based mainly on fixed material, and illustrations of sclerites and radula have been incomplete. We here present data from an investigation based on over 70 specimens from Norway (including the type material). Radula, sclerites and living specimens are illustrated.

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Rubavathi, Subbaiyan, Ganesan Ayyappadasan, Nagarajan Sangeetha, Thangavel Harini, Dhanuskodi Saranya et Prakash Harshapradha. « Studies on Antioxidant and Anti-obesity Activity of Salvia hispanica (Chia) Seeds Extracts ». Journal of Drug Delivery and Therapeutics 10, n^o 3-s (15 juin 2020) : 98–106. http://dx.doi.org/10.22270/jddt.v10i3-s.4169.

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Obesity is a condition in which large amount of fat is stored in adipose tissue. Obesity is the greatest risk for many diseases like coronary heart disease, type 2 diabetes millions associated with insulin resistance, arthritis disorder, hypertension and cancers. Currently, the available drugs for obesity have been associated with number of side effects when compared with allopathic drugs. Salvia hispanica was one of the member of Lamiaceae family, collected to study the antiobesity activity. Extraction of Salvia hispanica using different solvents was done and tested for the presence of phytochemical constituents and the antimicrobial activity was monitored to evaluate the zone of inhibition. Further, antioxidant potential activity such as DPPH, FRAP and H2O2 assay was studied. Percentage of inhibition of Salvia hispanica was calculated and was observed as in capturing the free radicals present in the body. The surface and cross-sectional morphology Salvia hispanica extract nanoparticles was examined by using SEM. High ALA content make chia a perfect as it is associated with lower incidence of Cardiovascular diseases. This metabolic syndrome is mediated by inflammatory pathways. Hence, the in vitro activity of anti-inflammatory assay was performed by inhibition of albumin denaturation and anti-obesity activity was performed by lipase inhibition assay. Thus the result indicates that the seed extracts of Salvia hispanica possess antiobesity activity. Keywords: Salvia hispanica, anti-obesity, cholesterol, Antioxidant, lipase inhibition

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Su, Xiangdong, Yichuang Wu, Meifang Wu, Jielang Lu, Shujie Jia, Xin He, Shuna Liu, Yuyang Zhou, Hui Xing et Yongbo Xue. « Regioisomers Salviprolin A and B, Unprecedented Rosmarinic Acid Conjugated Dinorditerpenoids from Salvia przewalskii Maxim ». Molecules 26, n^o 22 (18 novembre 2021) : 6955. http://dx.doi.org/10.3390/molecules26226955.

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Salvia przewalskii Maxim is a perennial plant from the genus Salvia (family Lamiaceae). The roots of S. przewalskii were long used as a traditional herb to treat blood circulation related illnesses in China. As part of our continuing interest in polycyclic natural products from medicinal plants, two unprecedented adducts comprised of a dinor-diterpenoid and a 9′-nor-rosmarinic acid derivative, linked by a 1,4-benzodioxane motif (1 and 2), were isolated from the roots of S. przewalskii. Their structures were established by extensive spectroscopic approaches including 1D, 2D NMR, and HRFABMS. Their cytotoxic activities against five human tumor cell lines were evaluated.

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Zhang, Ji Hong, Meng Qiong Shi, Wen Yan Yang, Guang Yao Liu, Dan Dan Liu, Wei Deng, Hui Lin Qin et Zhi Feng Chen. « Cardioprotective Effects of Aqueous Extract of Salvia miltiorrhiza on Heart Failure is Related to SDF-1/CXCR4 Axis and Bcl-2 Family Expressions ». Advanced Materials Research 998-999 (juillet 2014) : 200–205. http://dx.doi.org/10.4028/www.scientific.net/amr.998-999.200.

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Salvia Miltiorrhizae Bge, a popular Chinese herb has been widely adopted for use in Chinese hospitals for both the prevention and the active management of cardiovascular disease. there is no study on its cardioprotective effects against HF and more importantly, the underlying mechanisms of its beneficial effects by SDF-1/CXCR4 axis remain poorly understood. This study was performed to investigate the protective effects and possible mechanism of aqueous extract of Salvia miltiorrhiza (AESM) on HF rats. In the study, cardioprotective effects of AESM on HF rats was evaluated by herat function, myocardial pathology, myocardial cell proliferation, SDF-1, CXCR4 and Bcl-2 family mRNA expressions. In the experiment, we found that AESM exerted beneficially protective effects on the HF rats, mainly recoverying normal heart function, myocardial pathology and myocardial cell proliferation. The underlying mechanism of these protective effects of AESM appeared to involve improving the SDF-1/CXCR4 axis and Bcl-2 family expressions.

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Trudel, Marie Claude G., et J. K. Morton. « Pollen morphology and taxonomy in North American Labiatae ». Canadian Journal of Botany 70, n^o 5 (1 mai 1992) : 975–95. http://dx.doi.org/10.1139/b92-122.

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Pollen morphology is described and illustrated based on SEM studies of 118 species of Labiatae (Lamiaceae) native to North America. These include representatives of all the 36 native genera. Pollen in this family is subspheroidal and either tricolpate (subfamily Lamioideae) or hexacolpate (subfamily Nepetoideae). In most of the genera and species, the tectum is conspicuously perforated with or without a supratectal reticulum. A key to facilitate identification of the pollen of the North American Labiatae is provided. The value of pollen as a taxonomic character in this family is discussed. Pollen provides the primary basis for recognition of subfamilies in the Labiatae, but at the tribal level only the Ajugeae has distinctive pollen. Several genera, notably Collinsonia, Salvia, Teucrium, and Trichostema, have pollen that is very different from other genera in this study. At the infrageneric level pollen provides valuable taxonomic characters in several genera, notably Hyptis, Monardella, Salvia, Stachys, Teucrium, and Trichostema. Key words: Labiatae, Lamiaceae, pollen, SEM, North America.

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Ahmad, V. U., M. Zahid, M. S. Ali, S. Ahmad, Z. Ali, M. Z. Iqbal et R. B. Tareen. « Buchariate : An Aromatic Ester from Salvia bucharica ». Scientia Pharmaceutica 68, n^o 4 (12 décembre 2000) : 429–33. http://dx.doi.org/10.3797/scipharm.aut-00-39.

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Salvia bucharica belonging to the family Lamiaceae (Labiatae), afforded a new aromatic ester named buchariate [1-(p-hydroxybenzoyloxy)-3-oxo-octane (1)] along with twelve known constituents for the first time from our investigated source. The structures of all the isolated constituents were determined through spectroscopic techniques and comparison with literature values. The structure of new constituent (1) was elucidated through extensive 2-D NMR experiments.

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Lu, Tsuo-Cheng, Yi-Hsiu Wu, Wei-Yu Chen et Yu-Chiang Hung. « Targeting Oxidative Stress and Endothelial Dysfunction Using Tanshinone IIA for the Treatment of Tissue Inflammation and Fibrosis ». Oxidative Medicine and Cellular Longevity 2022 (7 avril 2022) : 1–20. http://dx.doi.org/10.1155/2022/2811789.

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Salvia miltiorrhiza Burge (Danshen), a member of the Lamiaceae family, has been used in traditional Chinese medicine for many centuries as a valuable medicinal herb with antioxidative, anti-inflammatory, and antifibrotic potential. Several evidence-based reports have suggested that Salvia miltiorrhiza and its components prevent vascular diseases, including myocardial infarction, myocardial ischemia/reperfusion injury, arrhythmia, cardiac hypertrophy, and cardiac fibrosis. Tanshinone IIA (TanIIA), a lipophilic component of Salvia miltiorrhiza, has gained attention because of its possible preventive and curative activity against cardiovascular disorders. TanIIA, which possesses antioxidative, anti-inflammatory, and antifibrotic properties, could be a key component in the therapeutic potential of Salvia miltiorrhiza. Vascular diseases are often initiated by endothelial dysfunction, which is accompanied by vascular inflammation and fibrosis. In this review, we summarize how TanIIA suppresses tissue inflammation and fibrosis through signaling pathways such as PI3K/Akt/mTOR/eNOS, TGF-β1/Smad2/3, NF-κB, JNK/SAPK (stress-activated protein kinase)/MAPK, and ERK/Nrf2 pathways. In brief, this review illustrates the therapeutic value of TanIIA in the alleviation of oxidative stress, inflammation, and fibrosis, which are critical components of cardiovascular disorders.

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Y. Muttalib, Lana, et Alaadin M. Naqishbandi. « Antibacterial and Phytochemical Study of Iraqi Salvia officinalis Leave Extracts ». Iraqi Journal of Pharmaceutical Sciences ( P-ISSN 1683 - 3597 E-ISSN 2521 - 3512) 21, n^o 1 (28 mars 2017) : 93–97. http://dx.doi.org/10.31351/vol21iss1pp93-97.

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Sage (Salvia officinalis), belong to Labiatae family is indigenous to Iraq and other Mediterranean areas but now cultivated world- wide, principally for its use as culinary herb. In the present study preliminary screening for the important phytochemical natural product groups indicated the presence of flavonoid, saponin, hyrolysable and condensed tannin groups. The antibacterial activity of two concentrations 10 mg/ml and 100 mg/ml of chloroform and hydroalcoholic extracts from Salvia officinalis leaves was evaluated against four strains of gram negative bacteria (Escherichia coli, Pseudomonas arigenossa, Klebsiella pneumonia, and Proteus spp) and two strains of gram positive bacteria (Staphylococcus aureus, Bacillus cerus) using agar well diffusion method. Chloroform extract 100mg/ml was found active against two types of bacteria, Staphylococcus aureus with MIC of 90 mg/ml and Proteus spp with MIC of 80 mg/ml. Bioassay guided separation using TLC led to the separation of 6 constituents from the active extract, one of them was identified as thujone. Key words: Salvia officinalis, Antibacterial, TLC, Thujone.

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Alijanpoor, Behnaz, et Masoumeh Safaeishakib. « CYTOMIXIS AND MEIOTIC ABNORMAL BEHAVIOR RELATED IN SOME SELECTED SPECIES OF THE GENUS Salvia L. (Lamiaceae) FROM IRAN ». Acta Scientifica Malaysia 6, n^o 2 (2022) : 34–37. http://dx.doi.org/10.26480/asm.02.2022.34.37.

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In this research, the cytogenetic characteristics, phases of meiosis, abnormality during meiosis, variety of pollen grains, and cytomixis phenomenon have been studied. Populations of 10 species belonging to Salvia L. have been collected from different geographical regions of Iran. Cytomixis was recorded during meiosis I in three species of Salvia (S. nemorosa, S. staminea, S. verticellata) of the Lamiaceae family. Cytomixis and other associated meiotic abnormalities such as chromatin stickiness, clumping of metaphase -1, laggards, bridges, aberrations anaphase I, II, and micronuclei in the species reported into pollen sterility and some variable sizes. It can be said all of these are dependent on each other to create some abnormalities. Cytomixis and chromosome migration occurre in diploid and polyploid meiocytes.

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Zerova, M., L. Seryogina et Yu Karimpour. « New Species of the Chalcidoid Wasps of the Families Eurytomidae and Torymidae (Hymenoptera, Chalcidoidea) from Iran ». Vestnik Zoologii 42, n^o 6 (1 janvier 2008) : e101-e108. http://dx.doi.org/10.2478/v10058-008-0016-0.

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New Species of the Chalcidoid Wasps of the Families Eurytomidae and Torymidae (Hymenoptera, Chalcidoidea) from Iran Three new species of the Family Eurytomidae (Eurytoma lactucae Zerova, sp. n.; Bruchophagus trjapitzini Zerova, sp. n.; Nikanoria shohadae Zerova, sp. n.) and two species of Family Torymidae (Glyphomerus flavabdomen Zerova, sp. n.; Cryptopristus salviae Zerova, sp. n.) are described from Iran; ten palearctic species from the same Families are indicated for Iranian fauna for the first time (Eurytoma abdita Zerova, E. calicotomae Zerova, Eurytoma robusta Mayr, Bruchophagus astragali Fedoseeva, Adontomerus impolitus Askew et Nieves, Exopristoides hypecoi Zerova et Stojanova, Exopristus trigonomerus Ruschka, Idiomacromerus papaveris (Förster), Glyphomerus aylax Stojanova, Pseudotorymus militarsis (Boheman).

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Çardaklı, Ebru, Adem Bardak et Muzaffer Özdemir. « Doğu Akdeniz Bölgesinden Toplanan Bazı Adaçayı Türlerinin Genetik Farklılıklarının Belirlenmesi ». Turkish Journal of Agriculture - Food Science and Technology 5, n^o 6 (14 juillet 2017) : 695. http://dx.doi.org/10.24925/turjaf.v5i6.695-700.1183.

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Sage (Salvia spp.) is the most important and largest genus of the Lamiaceae family, and the popularity among medical plants is increasing. Sage plant is widely used in pharmaceutical, food and spice industries and as tea by many people. The fact that the plant may be marketed after being collected uncontrollably from the nature threatens its future. Therefore, it is necessary to put these species under protection and to start breeding projects as well to do genetic characterization of them. For this purpose, in the study, 11 different sage species from the Eastern Mediterranean region were collected and genetic differences among species were determined using SRAP (Sequence dependent replicated polymorphism) markers. As the result of our experiments, average polymorphism content, allele number and polymorphism information content (PIC) of the species were calculated as 90.91%, 4.2 and 0.91, respectively. The PIC values ranged from 0.04 to 0.99. While the average genetic difference among species was determined as 43.15%, the highest genetic difference, which was between Salvia aucheri spp. aucheri and Salvia aramiensis, was found to be 61.46%. The least genetic difference, on the other hand, was detected between Salvia tomentosa and Salvia hypergeia species with 22.62% similarity. Additionally, according to the observations made through the study, the SRAP markers we used were thought to be reliable for the genetic characterization of sage species. In breeding programs where interspecies dissimilarities are considered, selecting parental species with high genetic differences will increase the success.

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Aghaei, Zahra, Majid Talebi et Mehdi Rahimmalek. « Assessment of genetic diversity within and among sage (Salvia) species using SRAP markers ». Plant Genetic Resources 15, n^o 3 (1 décembre 2015) : 279–82. http://dx.doi.org/10.1017/s1479262115000593.

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Salvia (sage) is the most important and largest genus of the Lamiaceae family. High similarities among species in this genus lead to difficulty in its systematic identification. Despite its economic importance, limited molecular studies have been conducted to evaluate the genetic diversity among and within Salvia species. In this study, SRAP (sequence-related amplified polymorphism) markers, which targeted ORFs (open reading frames) as functional regions in the genome, were used to detect the genetic diversity of five Salvia species (S. virgata Jacq., S. nemorosa L., S. officinalis L., S. cereal L. and S. sclarea L.). Fourteen primer combinations (PCs) were amplified by 265 fragments on 54 genotypes, in which 255 (96%) were polymorphic. The average polymorphism information content (PIC) value was 0.308 over all PCs. The genetic distance among species ranged from 0.126 (between S. virgata Jacq. and S. nemorosa L.) to 0.568 (between S. nemorosa L. and S. sclarea L.). Based on Jaccard's similarity coefficient and UPGMA algorithm, cluster analysis separated different species (r= 0.920). The results showed high genetic differentiation (Fst= 0.337) and negligible gene flow (Nm= 0.750) among species. Owing to the high genetic variation among and within Salvia species, it serves as a rich source of germplasm with potential for use in breeding programmes.

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Dossymbetova, Symbat, Aigul Amirova, Taira Kurbangaliyeva, Khalima Abdresh et Gulzhan Kurtibayeva. « Germination of seeds of medicinal plants Origanum vulgare L. and Salvia officinalis L. in vitro ». Bulletin of the Karaganda University. “Biology, medicine, geography Series” 102, n^o 2 (30 juin 2021) : 23–29. http://dx.doi.org/10.31489/2021bmg2/23-29.

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The problem of biodiversity conservation and rational use of natural resources remains one of the most pressing problems for countries around the world. To maintain the stability of biological resources a sufficiently developed basis for their reproduction is required, which, in turn requires a preliminary study of the developmental features of individual organisms both in the natural environment and during their introduction into the cultural environment. A special place among the spice plants is occupied by the Lamiaceae Lindl. family. It is rich in medicinal and essential oil plants, which are widely used in family medicine, as well as in folk medicine and food industry, perfumery and cosmetic industries. Such plants include Origanum vulgare and Salvia officinalis. In addition, both plant species are added as phytobiotics to animal feed. The article deals with sterilization of seeds of medicinal plants Origanum vulgare L. and Salvia officinalis L. and the effect of sterilization methods on seed germination. For in vitro cultivation an aseptic, undamaged pure culture was obtained from the original plant material, and the most optimal method for sterilizing the seeds of these medicinal plants was chosen.

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Sajewicz, Mieczysław, Dorota Staszek, Łukasz Wojtal, Teresa Kowalska, Michał Ł. Hajnos et Monika Waksmundzka-Hajnos. « Binary HPLC-Diode Array Detector and HPLC-Evaporative Light-Scattering Detector Fingerprints of Methanol Extracts from the Selected Sage (Salvia) Species ». Journal of AOAC INTERNATIONAL 94, n^o 1 (1 janvier 2011) : 71–76. http://dx.doi.org/10.1093/jaoac/94.1.71.

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Abstract This study is focused on an important family of the sage (Salvia) species, with Salvia officinalis L. having a long-established position in European traditional medicine. Binary fingerprints (chromatographic profiles) of six different sage species were compared using HPLC coupled with two different detectors: the diode-array detector and the evaporative light-scattering detector. Advantages of using binary fingerprinting over single-detector fingerprinting are demonstrated and discussed, with selected examples. Experimental data are provided for a comparison of the chemical composition of sage samples originating from two harvesting seasons (2007 and 2008). A number of phytochemical standards (i.e., certain phenolic acids, flavonoids, and coumarin) were used that allowed identification and semiquantitative estimation of these particular compounds in the analyzed methanol extracts.

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Özcan, İmge İhsane, Olcay Arabacı et Neval Gül Öğretmen. « Farklı Çimlendirme Uygulamalarının Adaçayı Türlerine (Salvia fruticosa, S. officinalis, S. pomifera ve S. tomentosa) Etkisi ». Turkish Journal of Agriculture - Food Science and Technology 2, n^o 5 (27 mai 2014) : 203. http://dx.doi.org/10.24925/turjaf.v2i5.203-207.58.

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Sage, which belongs to Labiatae family and contains essential oils, is a typical Mediterranean plant. Being an important and one of the biggest species of this family, sage is said to be named being inspired by the word "Salveo" which means “saver” or “healer” in Latin. Salvia genus is represented by about 900 species on earth. There are 97 natural species of this genus in Turkey’s flora. There is dormancy in seeds of Salvia genus and having mucilage-like seed-coats is an inhibiting factor for germination. Seed germination studies of these species are of great importance in determining production strategies. This research is carried out at 25/15°C, 12 hours in light and 12 hours in dark environment to determine the effects of various germination applications (ethylene, gibberellin, PEG 8000, salicylic acid and seaweed) and pre-treatments (pre-drying, pre-cooling and untreated) in four species (S. fruticosa, S. officinalis, S. pomifera, S. tomentosa). These trials were conducted at the Department of Field Crops Laboratory of Adnan Menderes University according to completely randomized design with three factors with three replications. Important differences were observed about the germination rate and germination power among the species.

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Klaus, Anita, Damir Beatovic, Miomir Niksic, Slavica Jelacic, Viktor Nedovic et Tanja Petrovic. « Influence of ethereal oils extracted from Lamiaceae family plants on some pathogen microorganisms ». Zbornik Matice srpske za prirodne nauke, n^o 115 (2008) : 65–74. http://dx.doi.org/10.2298/zmspn0815065k.

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As pathogen microorganisms can be found in different kinds of food, using of natural antimicrobial compounds, like ethereal oils, could be important in the preservation of different groceries. To evaluate antimicrobial activity of ethereal oils extracted from Lamiaceae family plants - Rosmarinus officinalis L., Thymus vulgaris L., Majorana hortensis M o e n c h, and Salvia officinalis L screening of their effects against food borne bacteria Staphylococcus aureus, Enterococcus faecalis, Proteus mirabilis, Salmonella enteritidis, Pseudomonas aeruginosa, Bacillus cereus, Bacillus subtilis, Escherichia coli, Escherichia coli O157:H7, Listeria monocytogenes and yeasts Candida albicans and Saccharomyces cerevisiae were applied. All investigated concentrations and pure Majorana hortensis and Thymus vulgaris ethereal oils showed microbicidal effect on majority of tested microorganisms.

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Abd Rashed, Aswir, et Devi-Nair Gunasegavan Rathi. « Bioactive Components of Salvia and Their Potential Antidiabetic Properties : A Review ». Molecules 26, n^o 10 (20 mai 2021) : 3042. http://dx.doi.org/10.3390/molecules26103042.

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The utilization of therapeutic plants is expanding around the globe, coupled with the tremendous expansion of alternative medicine and growing demand in health treatment. Plants are applied in pharmaceuticals to preserve and expand health—physically, mentally and as well as to treat particular health conditions and afflictions. There are more than 600 families of plants identified so far. Among the plants that are often studied for their health benefit include the genus of Salvia in the mint family, Lamiaceae. This review aims to determine the bioactive components of Salvia and their potential as antidiabetic agents. The search was conducted using three databases (PubMed, EMBASE and Scopus), and all relevant articles that are freely available in the English language were extracted within 10 years (2011–2021). Salvia spp. comprises many biologically active components that can be divided into monoterpenes, diterpenes, triterpenes, and phenolic components, but only a few of these have been studied in-depth for their health benefit claims. The most commonly studied bioactive component was salvianolic acids. Interestingly, S. miltiorrhiza is undoubtedly the most widely studied Salvia species in terms of its effectiveness as an antidiabetic agent. In conclusion, we hope that this review stimulates more studies on bioactive components from medicinal plants, not only on their potential as antidiabetic agents but also for other possible health benefits.

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Guliyeva, S. « Properties of Essential Oils of Annual Species of the Lamiaceae Family ». Bulletin of Science and Practice, n^o 11 (15 novembre 2022) : 42–47. http://dx.doi.org/10.33619/2414-2948/84/05.

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Data of the study and analysis of the essential oil properties of 5 species of Lamiaceae family (Salvia viridis L., Ocimum basilicum L., Satureja hortensis L., Ziziphora tenuior L., Clinopodium acinos (L.) Kuntze) common in the Lesser Caucasus botanical-geographical region is devoted in the paper. Essential oils were obtained from plants in different phases (0.12-3.06%), their physical and chemical constant features, qualitative and quantitative composition were determined depending on the effects of environmental conditions. Quantitative and, to some extent, qualitative changes occur in the composition of essential oils in various organs has been established. The essential oils of the studied species have an odor reminiscent of lemon and mint. The essential oil of these plants is a transparent substance that is lighter than water. To clarify the physicochemical properties of substances, their specific gravity (D2020), refractive index (n20D), acid number, ether number, and ether number after acetylation were determined.

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P, Sunojkumar, et Pradeep A K. « Salvia misella (Lamiaceae)—A new record for Asia from the southern Western Ghats of India ». Phytotaxa 230, n^o 3 (13 octobre 2015) : 281. http://dx.doi.org/10.11646/phytotaxa.230.3.7.

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The mint family, Lamiaceae is generally regarded as being one of the most highly derived plant families from the viewpoint of floral structures (Hedge 1992). The family is best known for their essential oils common to many members of the family and are a major source of culinary herbs. Within the subfamily Nepetoideae tribe Mentheae, the subtribe Salviineae includes 8 genera with about 954 species in the world (Harley et al. 2004). The genus Salvia L. (1753: 23) alone account for over 900 species in the subtribe and is the largest genera in Labiatae (Mabberley 2008). It is a tropical and subtropical genus mostly found in montane areas with the major diversity in Mediterranean, Central Asia, the highlands of Mexico and the Andes in South America (Rodrigues-Hahn et al. 1992).

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Liu, Rui, Peijin Zou, Zhu-Yun Yan et Xin Chen. « Identification, classification, and expression profile analysis of heat shock transcription factor gene family in Salvia miltiorrhiza ». PeerJ 10 (5 décembre 2022) : e14464. http://dx.doi.org/10.7717/peerj.14464.

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In response to abiotic stresses, transcription factors are essential. Heat shock transcription factors (HSFs), which control gene expression, serve as essential regulators of plant growth, development, and stress response. As a model medicinal plant, Salvia miltiorrhiza is a crucial component in the treatment of cardiovascular illnesses. But throughout its growth cycle, S.miltiorrhiza is exposed to a series of abiotic challenges, including heat and drought. In this study, 35 HSF genes were identified based on genome sequencing of Salvia miltiorrhiza utilizing bioinformatics techniques. Additionally, 35 genes were classified into three groups by phylogeny and gene structural analysis, comprising 22 HSFA, 11 HSFB, and two HSFC. The distribution and sequence analysis of motif showed that SmHSFs were relatively conservative. In SmHSF genes, analysis of the promoter region revealed the presence of many cis-acting elements linked to stress, hormones, and growth and development, suggesting that these factors have regulatory roles. The majority of SmHSFs were expressed in response to heat and drought stress, according to combined transcriptome and real-time quantitative PCR (qRT-PCR) analyses. In conclusion, this study looked at the SmHSF gene family using genome-wide identification, evolutionary analysis, sequence characterization, and expression analysis. This research serves as a foundation for further investigations into the role of HSF genes and their molecular mechanisms in plant stress responses.

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Madeddu, Silvia, Alessandra Marongiu, Giuseppina Sanna, Carla Zannella, Danilo Falconieri, Silvia Porcedda, Aldo Manzin et Alessandra Piras. « Bovine Viral Diarrhea Virus (BVDV) : A Preliminary Study on Antiviral Properties of Some Aromatic and Medicinal Plants ». Pathogens 10, n^o 4 (29 mars 2021) : 403. http://dx.doi.org/10.3390/pathogens10040403.

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Plant products provide an alternative and successful source of lead compounds for the pharmaceutical industry. The present study was aimed to evaluate, in cell-based assays, the antiviral properties of essential oils obtained from plants that commonly grow in Sardinia, Italy, against a broad spectrum of RNA/DNA viruses. The essential oils of Helichrisumitalicum (Roth) G. Don ssp. microphyllum (Willd.) Nyman, Laurus nobilis L., Mirtuscommunis L., Pistacia lentiscus L., Salvia officinalis L., Saturejathymbra L., Lavandula angustifolia Mill., Foeniculum vulgare Mill., and Eucalyptus globulus Labill. were extracted by hydrodistillation and analyzed by gas chromatography mass spectrometry (GC–MS). Interestingly, the essential oil of Salvia officinalis showed moderate activity against bovine viral diarrhea virus (BVDV), an enveloped RNA virus belonging to the Flaviviridae family. BVDV is responsible for several clinical manifestations in bovines, including respiratory, gastroenteric, and reproductive diseases, with a significant economic impact. With the aim to individuate the constituent of the Salvia officinalis responsible for the biological activity, we tested the major components of the oil: camphene, β-pinene, limonene, 1,8-cineole, cis-thujone, camphor, (E)-caryophyllene, and α-humulene. Here, we describe α-humulene as an active component that is non-cytotoxic and active against BVDV (EC50 = 36 µM). Its antiviral effects were evaluated using virucidal cytopathic effect inhibition and viral yield reduction assays. This is the first scientific report showing the anti BVDV effects of Salvia officinalis essential oil and α-humulene as the main active component.

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Rastakhiz, N., P. Aberoomand Azar, M. Saber Tehrani, M. Moradalizadeh et K. Larijani. « Comparison of the chemical components of essential oil extracted by MAHD and SPME methods from two species of Salvia from Iran ». International Journal of Life Sciences 9, n^o 2 (10 février 2015) : 61–64. http://dx.doi.org/10.3126/ijls.v9i2.12051.

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Salvia macrosiphon Boiss. and Salvia rhytidea Benth. species of the genus Salvia which are belong to the Lamiaceae family. At the Present report deals with the analysis comparison of the essential oils from aerial parts of S. macrosiphon and S. rhytidea growing wild in Iran obtained by hydrodistillation (HD) , microware assisted hydrodistillation (MAHD) and solid phase micro extraction (SPME) procedures and the collected essential oils was investigated by GC and GC-MS. The major compounds of essential oil of S. macrosiphon extracted by hydrodistillation were: Linalool(12.6%),Caryophyllene oxide(11.9%) , Octane(8.5%) and β-Eudesmol(7.1%). Also the main compounds of essential oil from S. macrosiphon extracted by microwave assisted hydrodistillation were: Caryophyllene oxide(21.8%) ,Linalool(18.8%) and β-Eudesmol (6.1%). In this study,the gas chromatogram was obtained of injection the essential oil from aerial parts of S.macrosiphon extracted by solid phase micro extraction ,was not helpful. Chemical composition of volatile compounds from dried aerial parts of Salvia rhytidea Benth. was extracted, by hydrodistillation and solid phase micro extraction methods but microwave assisted hydrodistillation method was not helpful . The major compounds of essential oil of S.rhytidea extracted by hydrodistillation were:Sabinene(12.8%),Spathulenol(12.4%),Germacren-D (6.7%) , β-Eudesmol (6.3%) and α - Cubebene(5.4%). Also the main compounds of essential oil from S. rhytidea extracted by solid phase micro extraction were: Sabinene (38.5%), Limonene(11.6%) , Myrcene (7.2%) and β-Pinene(5.5%).DOI: http://dx.doi.org/10.3126/ijls.v9i2.12051 International Journal of Life Sciences 9 (2) : 2015; 61-64

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Khohklova, K. O., L. I. Vyshnevska et O. A. Zdoryk. « Comparison of chromatographic profiles of essential oils in extracts of 13 species from Lamiaceae family ». Farmatsevtychnyi zhurnal, n^o 3 (9 juillet 2020) : 86–94. http://dx.doi.org/10.32352/0367-3057.3.20.09.

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The TLC essential oils profiles were being used conventionally for identification of herbal raw materials (HRM) of Lamiaceae family. Despite this, in recent years the European Pharmacopoeia to call in question the appropriateness of TLC on essential oils determination of Thyme and Wild Thyme, as well as Peppermint and Peppermint dry extract; these methods were replaced by HPTLC using ﬂavonoid proﬁle. This work aimed to establish the possibility of conducting HPTLC identification of methanolic extracts of 13 members of the Lamiaceae family in harmonized chromatographic conditions using chromatographic profiles on essential oils. The objects were methanolic extracts of HRM of Ukraine flora – Salvia officinalis, Salvia aethiopis, Thymus serpyllum, Thymus vulgaris, Origanum vulgare, Rosmarinus officinalis, Ocimum tenuiflorum (foreign origin), Mentha × piperita, Melissa officinalis, Orthosiphon stamineus, Agastache foeniculum, Leonurus cardiaca, Hyssopus officinalis, Marrubium vulgare, prepared from HRM that were purchased in Ukraine. The study wоas done by standardized HPTLC procedure using automatic HPTLC herbal system of CAMAG, Switzerland, at the base of CAMAG laboratory, Muttenz, Switzerland, and laboratory of ESTCCTI ESIPP, NUPh, Ukraine. Chromatography conditions: stationary phase – HPTLC plates Si 60 F254; mobile phase – toluene-ethylacetate (95:5); reference standards – borneol, bornyl acetate, cineole; derivatization – anisaldehyde reagent; detection: WRT, 254, 366 nm – before derivatization; WRT, 366 nm – after derivatization; sample preparation – methanolic extracts (100 mg/ml), extracted by shaking technique. In unified chromatographic conditions the HPTLC chromatographic fingerprints of essential oils of 13 Lamiaceae family species were established and evaluated. The most specific, intensive and reproducible HPTLC fingerprints were for Sage and Rosemary extracts. Moreover, fingerprints of Sage, Thyme, Rosemary, Origanum, Ocimum and Peppermint shown specific zones useful for differentiation of different genera of Lamiaceae family. For setting relative acceptance criteria for each of the species the validation for specific zones that were detected should be done.

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Li, Heqin, Caili Li, Yuxing Deng, Xuwen Jiang et Shanfa Lu. « The Pentatricopeptide Repeat Gene Family in Salvia miltiorrhiza : Genome-Wide Characterization and Expression Analysis ». Molecules 23, n^o 6 (6 juin 2018) : 1364. http://dx.doi.org/10.3390/molecules23061364.

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Kolumbayeva, S. Zh, A. V. Lovinskaya, N. T. Bekmagambetova et S. K. Abilev. « Antimutagenic activity of medicinal plants Salvia officinalis L. and Origanum vulgare L. (family Lamiaceae) ». International Journal of Biology and Chemistry 12, n^o 2 (2019) : 40–48. http://dx.doi.org/10.26577/ijbch-2019-i2-5.

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Li, Jiang, Caili Li et Shanfa Lu. « Identification and characterization of the cytosine-5 DNA methyltransferase gene family in Salvia miltiorrhiza ». PeerJ 6 (5 mars 2018) : e4461. http://dx.doi.org/10.7717/peerj.4461.

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Cytosine DNA methylation is highly conserved epigenetic modification involved in a wide range of biological processes in eukaryotes. It was established and maintained by cytosine-5 DNA methyltransferases (C5-MTases) in plants. Through genome-wide identification, eight putative SmC5-MTase genes were identified from the genome of Salvia miltiorrhiza, a well-known traditional Chinese medicine material and an emerging model medicinal plant. Based on conserved domains and phylogenetic analysis, eight SmC5-MTase genes were divided into four subfamilies, including MET, CMT, DRM and DNMT2. Genome-wide comparative analysis of the C5-MTase gene family in S. miltiorrhiza and Arabidopsis thaliana, including gene structure, sequence features, sequence alignment and conserved motifs, was carried out. The results showed conservation and divergence of the members of each subfamily in plants. The length of SmC5-MTase open reading frames ranges widely from 1,152 (SmDNMT2) to 5,034 bp (SmMET1). The intron number of SmC5-MTases varies between 7 (SmDRM1) and 20 (SmCMT1 and SmCMT2b). These features were similar to their counterparts from Arabidopsis. Sequence alignment and conserved motif analysis showed the existence of highly conserved and subfamily-specific motifs in the C5-MTases analyzed. Differential transcript abundance was detected for SmC5-MTases, implying genome-wide variance of DNA methylation in different organs and tissues. Transcriptome-wide analysis showed that the transcript levels of all SmC5-MTase genes was slightly changed under yeast extract and methyl jasmonate treatments. Six SmC5-MTases, including SmMET1, SmCMT1, SmCMT2a, SmCMT2b, SmCMT3 and SmDRM1, were salicylic acid-responsive, suggesting the involvement of SmC5-MTases in salicylic acid-dependent immunity. These results provide useful information for demonstrating the role of DNA methylation in bioactive compound biosynthesis and Dao-di herb formation in medicinal plants.

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Zhang, Linsu, Bin Wu, Degang Zhao, Caili Li, Fenjuan Shao et Shanfa Lu. « Genome-wide analysis and molecular dissection of the SPL gene family in Salvia miltiorrhiza ». Journal of Integrative Plant Biology 56, n^o 1 (20 novembre 2013) : 38–50. http://dx.doi.org/10.1111/jipb.12111.

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Pieracci, Ylenia, Daniela Ciccarelli, Silvia Giovanelli, Luisa Pistelli, Guido Flamini, Claudio Cervelli, Francesca Mancianti, Simona Nardoni, Fabrizio Bertelloni et Valentina Virginia Ebani. « Antimicrobial Activity and Composition of Five Rosmarinus (Now Salvia spp. and Varieties) Essential Oils ». Antibiotics 10, n^o 9 (9 septembre 2021) : 1090. http://dx.doi.org/10.3390/antibiotics10091090.

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Salvia rosmarinus Spenn. and Salvia jordanii J.B.Walker are aromatic evergreen shrubs belonging to the Lamiaceae family. Their aerial parts have been used since ancient times as natural preservatives. The present study reported the investigation of the chemical profile and the extraction yield of the essential oils (EOs) obtained from the dried aerial parts of four cultivars of Salvia rosmarinus (‘Boule’; ‘Vicomte de Noailles’; ‘Gorizia’; ‘Joyce de Baggio’) and the species S. jordanii, together with their antibacterial and antifungal activities. The phytochemical investigation evidenced a predominance of oxygenated monoterpenes in all the samples (57.5–77.1%), except in ‘Boule’, in which the hydrocarbon form prevailed (50.2%). Principal Component Analysis (PCA) of the matrix taxa × compounds showed that nine compounds have a significant discriminating function between the samples. ‘Vicomte de Noailles’ was characterized by high amounts of camphor and 14-hydroxy-9-epi-(E)-caryophyllene, while ‘Gorizia’ and Jord differed in their predominance of camphene, borneol, bornyl acetate, and α-humulene. Lastly, ‘Boule’ and ‘Joyce de Baggio’ segregated separately and were characterized by high amounts of α-pinene, myrcene, and verbenone. The selected EOs presented a moderate antibacterial activity on the tested bacterial strains and resulted not active on the tested yeast species.

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Zare, Habibeh. « Effects of Salvia Officinalis Extract on the Breast Cancer Cell Line ». SciMedicine Journal 1, n^o 1 (1 mars 2019) : 25–29. http://dx.doi.org/10.28991/scimedj-2019-0101-4.

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Background: Common sage (Salvia officinalis L., Lamiaceae) is an aromatic and medicinal plant well known for its antioxidant properties. This plant belongs to Lamiaceae family and has many pharmaceutical properties. Some in vivo studies have shown the biological antioxidant effects of sage. As a member of Salvia officinalis Labiatae, sage is also known as “Maryam flower” in Iran. Sage importance lies in its therapeutic potential. It has been exploited as an anti-spasmodic, astringent, sedative, anti-hyperglycemic, and anti-inflammatory agent in Iranian medicine. Objective: Studying the anticancer effects of the compounds in Salvia officinalis extracts, such as cineol and camphor. Methods: Cancer was induced by DMBA (dimethyl-benzantheracene) dissolved in sunflower oil for 4 weeks. The case group was treated with sage leaf hydroalcoholic extract for 4 weeks; while the controls received distilled water. Result: Angiogenesis is a key process in cancer spread and metastasis. The hydroalcoholic extract of garden sage halted angiogenesis in the breast cell line of both human and mouse models; the highest impact was observed in hexane extract. Findings indicated the therapeutic effects of garden sage (i.e. its in vitro anti-angiogenesis activity and anti-migratory properties). Conclusion: Saliva officinalis can potentially prevent breast cancer.

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COBO, M. CARMEN, et KEVIN M. KOCOT. « On the diversity of abyssal Dondersiidae (Mollusca : Aplacophora) with the description of a new genus, six new species, and a review of the family ». Zootaxa 4933, n^o 1 (18 février 2021) : 63–97. http://dx.doi.org/10.11646/zootaxa.4933.1.3.

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So far, of the 292 known species of solenogasters (Mollusca, Aplacophora), 62 belong to the clade Pholidoskepia Salvini-Plawen, 1978. Of these, only two have an abyssal distribution (3500–6000 m depth). Among Pholidoskepia, Dondersiidae Simroth, 1893 is the most diverse family. This study contributes to the knowledge of this family with the description of one new genus and six new species from the abyssal South Atlantic Ocean: Dondersia ? foraminosa sp. n., Nematomenia divae sp. n., Nematomenia brasiliensis sp. n., Nematomenia ? guineana sp. n., Helluoherpia vieiralaneroi sp. n. and Inopinatamenia (gen. n.) calamitosa sp. n. Specimens were collected during DIVA (Latitudinal Gradients of Deep-Sea BioDIVersity in the Atlantic Ocean) expeditions in the Guinea (DIVA 2 Me 63/2, 2005) and Brazil (DIVA 3 Me 79/1, 2008) Basins. Specimens were characterized based primarily on the sclerites and internal anatomy, which was studied using histology. The importance of the radula and mantle sclerites for taxonomy is emphasized. Amended diagnoses for the family and some genera within this family are provided. This contribution increases the described diversity of Dondersiidae to ten genera and 38 species and highlights the need for more study of solenogasters in the deep sea.

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Spiridon, Iuliana, Ruxanda Bodirlau et Carmen-Alice Teaca. « Total phenolic content and antioxidant activity of plants used in traditional Romanian herbal medicine ». Open Life Sciences 6, n^o 3 (1 juin 2011) : 388–96. http://dx.doi.org/10.2478/s11535-011-0028-6.

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AbstractA number of herbal plants from Romania widely used as natural food additives or for health promotion in traditional medicine were investigated for their antioxidant activity. Methanol extracts were obtained from plants belonging to the Lamiaceae family (lavender Lavandula angustifolia L.; lemon balm Melissa officinalis; sage Salvia officinalis; oregano Origanum vulgare L.; rosemary Rosmarinus officinalis L.; thyme Thymus vulgaris L.; mullein Verbascum phlomoides; mint Mentha longifolia), Clusiaceae family (St John’s wort Hypericum perforatum L.), and Compositae family (elecampane Inula helenium). Total phenolic concentration was determined using the Folin-Ciocalteu phenol reagent method, while total flavonoids were measured using the aluminium chloride colorimetric method. Relationships between total antioxidant activity and composition of plant extracts were evaluated. Origanum vulgare extract showed the highest antioxidant activity and total phenolic content compared to the other plants extracts. A positive correlation was observed between total antioxidant activity and total phenolic content of the analyzed extracts.

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Sucur, Jovana, Dejan Prvulovic, Goran Anackov et Djordje Malencic. « Antioxidant potential of Clinopodium menthifolium, Satureja montana and Salvia sclarea (Lamiaceae) extracts ». Zbornik Matice srpske za prirodne nauke, n^o 134 (2018) : 9–18. http://dx.doi.org/10.2298/zmspn1834009s.

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Plants which belong to Lamiaceae family are good potential sources of natural antioxidants useful for preventing oxidative stress-related diseases. The food industry is becoming increasingly interested in aromatic herbs, including plants from Lamiaceae family, because of their anti-inflammatory properties and antioxidant activities, due to growing consumer demands for healthy foods of natural origin. In the present investigation, the comparative antioxidant potential of aqueous and acetone extracts of three Lamiaceae species are described: Clinopodium menthifolium (Host), Satureja montana L., and Salvia sclarea L., using three methods: 2,2-azinobis (3-ethyl-benzothiazoline-6-sulfonic acid) radical (ABTS) scavenging, 1,1-Diphenyl-2-picrylhydrazyl radical (DPPH) scavenging, and ferric reducing antioxidant power (FRAP) assay and their correlations with total phenolic and flavonoid contents. Antioxidant capacity showed a positive relationship comparing three above mentioned tests. Antioxidant capacity detected by antioxidant ABTS, DPPH, and FRAP assays was positively correlated with total phenolics content. Aqueous extract of C. menthifolium showed greater antioxidant potential.

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Ydyrys, Alibek, Nazgul Zhaparkulova, Arailym Aralbaeva, Aigul Mamataeva, Ainur Seilkhan, Sayagul Syraiyl et Maіra Murzakhmetova. « Systematic Analysis of Combined Antioxidant and Membrane-Stabilizing Properties of Several Lamiaceae Family Kazakhstani Plants for Potential Production of Tea Beverages ». Plants 10, n^o 4 (30 mars 2021) : 666. http://dx.doi.org/10.3390/plants10040666.

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One of the most important compounds that exhibit a wide range of biological activities with especially strong antioxidant action are plant polyphenols. In the course of the experiment, the dose-dependent effects of polyphenols-rich extracts isolated from the Lamiaceae family Kazakhstani plants were studied on the processes of lipid peroxidation and on the degree of erythrocytes hemolysis. The activity of aqueous-ethanolic extracts from dried parts of plants, such as Origanum vulgare, Ziziphora bungeana, Dracocephalum integrifolium, Mentha piperita, Leonurus turkestanicus, Thymus serpyllum, and Salvia officinalis, was studied in a Wistar rat model. Lipid peroxidation (LPO) in liver microsomes was assessed by measuring malondialdehyde content in the form of thiobarbituric acid-reacting substances (TBARS). Estimation of osmotic resistance of isolated erythrocytes was evaluated based on hemoglobin absorbance. The amount of total phenolics in the extracts was measured using the Folin-Ciocalteu reagent method. Based on the results, Thymus serpyllum extract exhibited a significantly higher antioxidant activity (IC50 = 3.3 ± 0.7) compared to other plant extracts. Accordingly, among the extracts studied, those from Salvia officinalis, Thymus serpyllum, and Origanum vulgare show the most pronounced membrane-stabilizing activity. Antioxidant and antihemolytic properties of green tea and Origanum vulgare extract mixtures were similar to that of each individual plant extract. Similar results were obtained when the green tea extract was mixed with Mentha piperita, Ziziphora bungeana, and Dracocephalum integrifolium extracts, indicating no discernible synergistic interaction.

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Moghaddam, Masumeh, et Mamud Alikhani. « Two new species of mealybugs (Hemiptera, Coccoidea, Pseudococcidae) from Iran ». Journal of Entomological and Acarological Research 42, n^o 1 (23 avril 2010) : 11. http://dx.doi.org/10.4081/jear.2010.11.

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Polystomophora arakensis Moghaddam and Phenacoccus salviacus Moghaddam are described and illustrated in detail from Iran. The species P. arakensis was collected from the roots of Atraphaxis sp. (Family: Polygonaceae) and P. salviacus was collected from the leaves of Salvia bracteata (Family: Labiatae). The genera Phenacoccus and Polystomophora are briefly reviewed and a key to the Iranian species of Phenacoccus is provided.

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Picos-Salas, Manuel Adrian, José Basilio Heredia, Nayely Leyva-López, Dulce Libna Ambriz-Pérez et Erick Paul Gutiérrez-Grijalva. « Extraction Processes Affect the Composition and Bioavailability of Flavones from Lamiaceae Plants : A Comprehensive Review ». Processes 9, n^o 9 (18 septembre 2021) : 1675. http://dx.doi.org/10.3390/pr9091675.

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Lamiaceae plants are a widespread family of herbaceous plants with around 245 plant genera and nearly 22,576 species distributed in the world. Some of the most representative and widely studied Lamiaceae plants belong to the Ocimum, Origanum, Salvia, and Thymus genera. These plants are a rich source of bioactive molecules such as terpenes, flavonoids, and phenolic acids. In this sense, there is a subgroup of flavonoids classified as flavones. Flavones have antioxidant, anti-inflammatory, anti-cancer, and anti-diabetic potential; thus, efficient extraction techniques from their original plant matrixes have been developed. Currently, conventional extraction methods involving organic solvents are no longer recommended due to their environmental consequences, and new environmentally friendly techniques have been developed. Moreover, once extracted, the bioactivity of flavones is highly linked to their bioavailability, which is often neglected. This review aims to comprehensively gather recent information (2011–2021) regarding extraction techniques and their important relationship with the bioavailability of flavones from Lamiaceae plants including Salvia, Ocimum, Thymus, and Origanum.

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Esmaeili, Ghasem, Hamideh Fatemi, Mahnaz Baghani Baghani avval, Majid Azizi, Hossein Arouiee, Jamil Vaezi et Yashiharu Fujii. « Diversity of Chemical Composition and Morphological Traits of Eight Iranian Wild Salvia Species during the First Step of Domestication ». Agronomy 12, n^o 10 (10 octobre 2022) : 2455. http://dx.doi.org/10.3390/agronomy12102455.

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As one of the largest genera of the Lamiaceae family, Salvia has a wide distribution worldwide. Despite their great importance and medicinal use, most Salvia species are collected from their natural habitats, and some of them are endangered and vulnerable. This study aimed to evaluate the domestication process of eight Iranian native Salvia species. The studied species were cultivated and adapted to the cultivation area after two years, and then some of their important biochemical properties were investigated. According to some significant results, the root architecture was closely correlated with the climatic conditions of the species origins. The distribution of total dry matter varied widely among species; accordingly, S. sclarea and S. officinalis had 65.6% and 55.9% dry weights in their leaves, respectively. Moreover, S. nemorosa had a 24.3% dry weight in its flowers, while S. frigida (Jahrom), S. frigida (Targavar), S. virgata (Eghled), and S. macrosiphon had 44.6%, 43.3%, 46.0%, and 44.3% dry weights in their roots. The most potent antioxidant activity (IC50) was observed in the roots of S. macrosiphon (10.9 μg/mL) and S. sclarea (14.9 μg/mL), the stem of S. nemorosa (14.3 μg/mL), and the leaves of S. atropatana (14.0 μg/mL). Rosmarinic acid, a key phenolic substance in Salvia species, was present in the range of 0.24–0.47 mg/g dry weight. The essential oil content ranged from 0.35% in S. atropatana to 1.45% (w/w) in S. officinalis. β-caryophyllene, caryophyllene oxide, and germacrene D were the major ingredients of the essential oils. The cluster analysis based on the essential oil data revealed the most similarities between S. sclarea and S. macrosiphon, and a clear separation of S. virgate, S. syriaca, and S. officinalis from other species. Salvia spp. contain a wide variety of compounds of interest under cultivation, with S. sclarea having the greatest potential to profit from the production of medicinal compounds, such as phenolic compounds, flavonoids, and essential oils. Furthermore, S. officinalis, S. nemorosa, and S. sclarea are the best species for producing raw medicinal materials.

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Guarnaccia, Gilardi, Martino, Garibaldi et Gullino. « Species Diversity in Colletotrichum Causing Anthracnose of Aromatic and Ornamental Lamiaceae in Italy ». Agronomy 9, n^o 10 (5 octobre 2019) : 613. http://dx.doi.org/10.3390/agronomy9100613.

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Species of Colletotrichum are considered important plant pathogens, saprobes, and endophytes on a wide range of host plants. In Italy, several Colletotrichum species have been reported in glasshouse environments. In this study, we have explored the occurrence, diversity, and pathogenicity of Colletotrichum spp. associated with aromatic and ornamental plants belonging to the Lamiaceae family. Surveys were carried out during the 2011–2018 period in Liguria and Piedmont, Italy. A total of 19 Colletotrichum isolates were collected from symptomatic leaves and seeds of Ocimum basilicum (basil), Origanum vulgare (oregano) and different Salvia spp. A multi-locus phylogeny was established based on the basis of four genomic loci (ITS, GAPDH, ACT and TUB2). The aggressiveness of selected, representative isolates were tested. Colletotrichum isolates were identified as being members of three major species complexes: C. acutatum, C. destructivum, and C. gloeosporioides. Colletotrichum fioriniae, C. bryonicola, and C. fructicola were found in association with leaf lesions on Salvia leucantha, S. nemorosa, and S. greggii, respectively. Colletotrichum nigrum was isolated from twig lesions of S. greggii. Moreover, C. fioriniae and C. ocimi were found to be responsible for causing leaf anthracnose of oregano and basil, respectively. All the tested isolates were pathogenic and reproduced identical symptoms to those observed in commercial glasshouses. The present study improves our understanding of Colletotrichum species associated with several hosts belonging to the Lamiaceae family, which are cultivated extensively throughout Italy for different purpose, and provides information that may be useful for an effective disease management program.

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Li, Caili, Dongqiao Li, Hong Zhou, Jiang Li et Shanfa Lu. « Analysis of the laccase gene family and miR397-/miR408-mediated posttranscriptional regulation in Salvia miltiorrhiza ». PeerJ 7 (29 août 2019) : e7605. http://dx.doi.org/10.7717/peerj.7605.

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Salvia miltiorrhiza is one of the most commonly used traditional Chinese medicine materials. It contains important bioactive phenolic compounds, such as salvianolic acids, flavonoids and anthocyanins. Elucidation of phenolic compound biosynthesis and its regulatory mechanism is of great significance for S. miltiorrhiza quality improvement. Laccases (LACs) are multicopper-containing enzymes potentially involved in the polymerization of phenolic compounds. So far, little has been known about LAC genes in S. miltiorrhiza. Through systematic investigation of the whole genome sequence and transcriptomes of S. miltiorrhiza, we identified 65 full-length SmLAC genes (SmLAC1–SmLAC65). Phylogenetic analysis showed that 62 of the identified SmLACs clustered with LACs from Arabidopsis and Populus trichocarpa in seven clades (C1–C7), whereas the other three fell into one S. miltiorrhiza-specific clade (C8). All of the deduced SmLAC proteins contain four conserved signature sequences and three typical Cu-oxidase domains, and gene structures of most LACs from S. miltiorrhiza, Arabidopsis and P. trichocarpa were highly conserved, however SmLACs encoding C8 proteins showed distinct intron-exon structures. It suggests the conservation and diversity of plant LACs in gene structures. The majority of SmLACs exhibited tissue-specific expression patterns, indicates manifold functions of SmLACs played in S. miltiorrhiza. Analysis of high-throughput small RNA sequences and degradome data and experimental validation using the 5′ RACE method showed that 23 SmLACs were targets of Smi-miR397. Among them, three were also targeted by Smi-miR408. It suggests the significance of miR397 and miR408 in posttranscriptional regulation of SmLAC genes. Our results provide a foundation for further demonstrating the functions of SmLACs in the production of bioactive phenolic compounds in S. miltiorrhiza.

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GOH, C. J., et Y. HAHN. « Identification of a novel member of the family Betaflexiviridae from the hallucinogenic plant Salvia divinorum ». Acta virologica 63, n^o 04 (2019) : 373–79. http://dx.doi.org/10.4149/av_2019_401.

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