Bibliographies thématiques / Saccharomyces cerevisiae, healthy aging

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Littérature scientifique sur le sujet « Saccharomyces cerevisiae, healthy aging »

Auteur : Grafiati
Publié le 9 mars 2023
Mis à jour le 31 juillet 2025

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Articles de revues sur le sujet "Saccharomyces cerevisiae, healthy aging"

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Alugoju, Phaniendra, Chella Perumal Palanisamy, Naga Venkata Anusha Anthikapalli, et al. "Exploring the anti-aging potential of natural products and plant extracts in budding yeast Saccharomyces cerevisiae: A review." F1000Research 12 (December 17, 2024): 1265. https://doi.org/10.12688/f1000research.141669.2.

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Historically, plant derived natural products and their crude extracts have been used to treat a wide range of ailments across the world. Biogerontology research aims to explore the molecular basis of aging and discover new anti-aging therapeutic compounds or formulations to combat the detrimental effects of aging and promote a healthy life span. The budding yeast Saccharomyces cerevisiae has been, and continues to be, an indispensable model organism in the field of biomedical research for discovering the molecular basis of aging S. cerevisiae has preserved nutritional signaling pathways (such
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Su, Wei-Hsuan, Omar Ocegueda, Catherine Choi, et al. "SPERMIDINE TOXICITY IN MITOCHONDRIAL DNA-DEFICIENT SACCHAROMYCES CEREVISIAE." Innovation in Aging 6, Supplement_1 (2022): 444–45. http://dx.doi.org/10.1093/geroni/igac059.1740.

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Abstract Mitochondrial dysfunction is thought to play a significant role in aging and in manyhuman diseases. Over the last 20 years or so, a number of drugs have been found toextend lifespan in model organisms. Using ethidium bromide to deplete the yeastSaccharomyces cerevisiae of its mitochondrial DNA (mtDNA), we evaluated thedependence on functional mitochondrial in the action of five of these lifespan-extending compounds; dinitrophenol, metformin, rapamycin, resveratrol, andspermidine. None of them extended lifespan in mtDNA-deficient cells, demonstratinga requirement for functional mitocho
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Begum, Farhana, Jaroslav Kristof, Md Jahangir Alam, et al. "Exploring the Role of Microplasma for Controlling Cellular Senescence in Saccharomyces cerevisiae." Molecules 30, no. 9 (2025): 1970. https://doi.org/10.3390/molecules30091970.

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Cellular senescence plays a pivotal role in aging and stress response mechanisms. Controlling cellular senescence is essential for developing novel techniques to prevent aging or aging-related diseases and promote a healthy lifespan. This study explores the efficiency of cold atmospheric microplasma (CAM) for controlling cellular senescence in yeast Saccharomyces cerevisiae. Reactive oxygen and nitrogen species (RONS) generated by CAM influence key processes, such as the regulation of oxidative stress, alterations in membrane potential, and senescence-related epigenetic modifications. As a mar
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Ogita, Akira, Wakae Murata, Marina Hasegawa, et al. "PROLONGATION OF HUMAN LIFESPAN BY IMMATURE PEAR EXTRACT MEDIATED SIRTUIN-RELATED GENE EXPRESSION." Innovation in Aging 3, Supplement_1 (2019): S97. http://dx.doi.org/10.1093/geroni/igz038.365.

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Abstract Demographics of the world are changing rapidly with older populations growing at an unprecedented rate. Cellular senescence, a decline of cellular function due to aging, causes gradual loss of physiological functions. Several cellular senescence-related chronic diseases, such as metabolic syndrome, cardiovascular disease, cancer, osteoporosis, diabetes, and hypertension, negatively affect the quality of human life. Intervention in the cellular senescence process may reduce these incidences and slow the progression of age-related diseases, while contributing to the longevity of healthy
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Su, Wei-Hsuan, Jessica Smith, Evien Cheng, and Samuel Schriner. "EXPRESSION OF THE TARDIGRADE DAMAGE SUPPRESSOR PROTEIN IN THE YEAST SACCHAROMYCES CEREVISIAE." Innovation in Aging 7, Supplement_1 (2023): 770. http://dx.doi.org/10.1093/geroni/igad104.2489.

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Abstract Tardigrades are resilient organisms that can tolerate extremes in temperature, pH, pressure, and salinity. They are also exceptionally resistant to starvation, dehydration, and irradiation. The damage suppressor (Dsup) protein is thought to be unique to tardigrades and may act by coating and protecting nuclear DNA, particularly the nucleosomes. Nuclear DNA damage and mutation may be one of the driving forces of the aging process. In addition, there has been demonstrated a clear relationship between stress tolerance and aging. In this study, we are asking whether Dsup, when expressed i
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Kaya, Alaattin. "EVIDENCE THAT CONSERVED ESSENTIAL GENES ARE ENRICHED FOR PRO-LONGEVITY FACTORS." Innovation in Aging 7, Supplement_1 (2023): 769–70. http://dx.doi.org/10.1093/geroni/igad104.2487.

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Abstract At the cellular level, many aspects of aging are conserved across species. This has been demonstrated by numerous studies in simple model organisms like Saccharomyces cerevisiae, Caenorhabdits elegans, and Drosophila melanogaster. Functional genomic studies in these models have contributed enormously to our understanding of conserved genetic pathways influencing aging in evolutionarily divergent organisms. From this perspective, essential genes that are evolutionarily constrained and functionally conserved should be more relevant to the regulation and evolution of aging. However, beca
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Kitanovic, Ana, and Stefan Wölfl. "Fructose-1,6-bisphosphatase mediates cellular responses to DNA damage and aging in Saccharomyces cerevisiae." Mutation Research/Fundamental and Molecular Mechanisms of Mutagenesis 594, no. 1-2 (2006): 135–47. http://dx.doi.org/10.1016/j.mrfmmm.2005.08.005.

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Romano, Patrizia, Giacomo Braschi, Gabriella Siesto, Francesca Patrignani, and Rosalba Lanciotti. "Role of Yeasts on the Sensory Component of Wines." Foods 11, no. 13 (2022): 1921. http://dx.doi.org/10.3390/foods11131921.

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The aromatic complexity of a wine is mainly influenced by the interaction between grapes and fermentation agents. This interaction is very complex and affected by numerous factors, such as cultivars, degree of grape ripeness, climate, mashing techniques, must chemical–physical characteristics, yeasts used in the fermentation process and their interactions with the grape endogenous microbiota, process parameters (including new non-thermal technologies), malolactic fermentation (when desired), and phenomena occurring during aging. However, the role of yeasts in the formation of aroma compounds h
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Shalamitskiy, Maksim Yu, Tatiana N. Tanashchuk, Sofia N. Cherviak, Egor A. Vasyagin, Nikolai V. Ravin, and Andrey V. Mardanov. "Ethyl Carbamate in Fermented Food Products: Sources of Appearance, Hazards and Methods for Reducing Its Content." Foods 12, no. 20 (2023): 3816. http://dx.doi.org/10.3390/foods12203816.

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Ethyl carbamate, the ethyl ester of carbamic acid, has been identified in fermented foods and alcoholic beverages. Since ethyl carbamate is a probable human carcinogen, reduction of its content is important for food safety and human health. In alcoholic beverages, ethyl carbamate is mostly formed from the reaction of ethanol with urea, citrulline and carbamyl phosphate during fermentation and storage. These precursors are generated from arginine metabolism by wine yeasts and lactic acid bacteria. This review summarizes the mechanisms of ethyl carbamate formation, its impact on human health and
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Liu, Gang, Lei Yu, Yordan Martínez, et al. "Dietary Saccharomyces cerevisiae Cell Wall Extract Supplementation Alleviates Oxidative Stress and Modulates Serum Amino Acids Profiles in Weaned Piglets." Oxidative Medicine and Cellular Longevity 2017 (2017): 1–7. http://dx.doi.org/10.1155/2017/3967439.

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This research aims to evaluate the effects of dietary supplementation with Saccharomyces cerevisiae cell wall extract (SCCWE) on growth performance, oxidative stress, intestinal morphology, and serum amino acid concentration in weaned piglets. Utilizing a completely randomized design, 40 healthy piglets weaned at 21 d were grouped into 4 experimental treatments with 10 pigs per treatment group. Treatments consisted of a basal diet (T0), a basal diet with a 0.05% SCCWE (T1), a basal diet with a 0.10% SCCWE (T2), and a basal diet with a 0.15% SCCWE (T3). SCCWE supplementation increased the avera
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Thèses sur le sujet "Saccharomyces cerevisiae, healthy aging"

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RONZULLI, ROSSELLA. "The yeast Saccharomyces cerevisiae as a “road” from aging basic research to interventions for healthy aging." Doctoral thesis, Università degli Studi di Milano-Bicocca, 2016. http://hdl.handle.net/10281/102384.

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Tutti gli organismi viventi col passare del tempo invecchiano, ossia vanno incontro ad un progressivo ed irreversibile declino funzionale/fisiologico, accompagnato da un aumentato rischio di contrarre malattie. Tra i diversi fattori coinvolti nell’invecchiamento, i nutrient-sensing pathway di TORC1/Sch9 e Ras/PKA e le Sirtuine, una famiglia di deacetilasi NAD+-dipendenti, svolgono un ruolo prioritario. Essi sono evolutivamente conservati dal lievito all’uomo, e risultano, inoltre, mediare alcuni degli effetti della Calorie Restriction (CR), un intervento che consiste nel limitare l’apporto di
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STAMERRA, GIULIA. "Nutraceutical approaches to promote healthy aging: the yeast Saccharomyces cerevisiae for the discovery of anti-aging interventions." Doctoral thesis, Università degli Studi di Milano-Bicocca, 2019. http://hdl.handle.net/10281/241137.

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L’aumento dell’aspettativa di vita non è associato con un altrettanto aumento delle condizioni di salute nella popolazione anziana. Oggigiorno, un’ampia parte di popolazione al di sopra dei 65 anni soffre di molteplici malattie, molte delle quali debilitanti, come le malattie cardiovascolari, i tumori o i disordini neurodegenerativi. Questo aspetto ha aumentato l’interesse per le tematiche legate all’invecchiamento, enfatizzando l’importanza di ridurre il gap tra longevità salute durante l’invecchiamento. A questo proposito, gli sforzi di molte linee di ricerca sono focalizzati nel tentati
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Falcon, Alaric Antonio. "Building an episomal model of aging in saccharomyces cerevesiae." [Gainesville, Fla.] : University of Florida, 2004. http://wwwlib.umi.com/cr/ufl/fullcit?p3136937.

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Thesis (Ph.D.)--University of Florida, 2004.<br>Typescript. Title from title page of source document. Document formatted into pages; contains 117 pages. Includes Vita. Includes bibliographical references.
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Butler, Barbara L. "Separation of a brewing yeast strain of Saccharomyces cerevisiae based on cellular age." Thesis, McGill University, 2002. http://digitool.Library.McGill.CA:80/R/?func=dbin-jump-full&object_id=78334.

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In yeast, aging appears to be marked by a progressive impairment in cellular mechanisms, resulting in irreversible changes in physiology and morphology. To date, very little has been reported about the biochemical changes that occur in yeast as a function of individual cell aging. To investigate this further, six generations of a brewing yeast strain of Saccharomyces cerevisiae (NCYC 1239) were separated according to cellular age using continuous phased culturing and biotin-streptavidin magnetic cell sorting.<br>To obtain cells with no bud scars (virgin cells), a concentrated yeast slur
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Basa, Ranor C. B. "ERC Accumulation and Premature Aging: An Investigation of the Deletion of ASH1 in the Budding Yeast Saccharomyces cerevisiae." Scholarship @ Claremont, 2006. http://scholarship.claremont.edu/pomona_theses/119.

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This thesis concerns the asymmetric mechanism by which the "molecular aging clock" is reset in the budding yeast Saccharomyces cerevisiae, which is of great interest considering that many organisms' cells--including human stem cells--undergo this process. When yeast divides, it ages a generation, while daughter cells begin life at generation zero. One theory surrounding this process in yeast is the extrachromosomal rDNA circle (ERC) aging theory. ERCs are generated spontaneously in mother cells as they age, and thus accumulate exponentially in older cells. Daughter cells from young mothers ben
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Managbanag, JR. "Application of Shortest-Path Network Analysis to Identify Genes that Modulate Longevity in Saccharomyces cerevisiae." VCU Scholars Compass, 2008. http://scholarscompass.vcu.edu/etd/1613.

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Shortest-path network analysis was employed to identify novel genes that modulate longevity in the baker’s yeast Saccharomyces cerevisiae. Based upon a set of previously reported genes associated with increased life span, a shortest path network algorithm was applied to a pre-existing protein-protein interaction dataset in order to construct a shortest-path longevity network. To validate this network, the replicative aging potential of 88 single gene deletion strains corresponding to predicted components of the shortest path longevity network was determined. The 88 single-gene deletion str
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Shamalnasab, Mehrnaz. "Conserved Role of Acyl-CoA Binding Proteins in Life Span Regulation." Thesis, Lyon, École normale supérieure, 2012. http://www.theses.fr/2012ENSL0790.

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Depuis une vingtaine d’années, il est possible d’allonger la durée de vie génétiquement. Nombre d’études réalisées sur des espèces allant de la levure aux primates, ont permis d’identifier des cascades de signaux intracellulaires ayant un impact sur la longévité et la qualité du vieillissement. Il est important de noter que certaines de ces interventions réduisent considérablement l’incidence de cancers et de maladies liées au vieillissement chez les mammifères. Ceci témoigne des liens existant entre vieillissement et carcinogénèse et il probable que le développement de stratégies pharmacologi
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Anjos, Rafaela Maria Rios dos. "Mapeamento dos determinantes estruturais da proteína Rtg2p, envolvidos na sinalização retrógrada e no envelhecimento de Saccharomyces cerevisiae." Universidade de São Paulo, 2016. http://www.teses.usp.br/teses/disponiveis/87/87131/tde-26092016-110727/.

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Rtg2p é uma proteína que participa da sinalização retrógrada, uma via de comunicação da mitocôndria para o núcleo; também tem sido associada com a longevidade em S. cerevisiae. O objetivo deste trabalho foi identificar os determinantes estruturais de Rtg2p, envolvidos na sinalização retrógrada e no envelhecimento. Para isto foram produzidos treze mutantes pontuais a partir do desenho racional por decomposição de redes de correlação de aminoácidos (DRCN). Analisaram-se as cepas mutantes por ensaio de auxotrofia para glutamato, expressão do gene CIT2 e ensaio de longevidade replicativa. Em sua g
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Tahara, Erich Birelli. "Influência da restrição calórica no metabolismo bioenergético e estado redox de Saccharomyces cerevisiae e Kluyveromyces lactis." Universidade de São Paulo, 2012. http://www.teses.usp.br/teses/disponiveis/46/46131/tde-15052012-085726/.

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O envelhecimento envolve um progressivo declínio na eficiência metabólica dos sistemas biológicos ao longo do tempo. Embora não possa ser evitado, o envelhecimento pode ter seus fenótipos típicos mitigados em organismos submetidos à restrição calórica, um regime dietético que consiste em uma oferta diminuída de calorias. Ao longo do tempo, a levedura Saccharomyces cerevisiae mostrou-se um importante organismo modelo para o estudo de importantes marcas relacionadas ao envelhecimento, sobretudo por ser responsiva à restrição calórica. Através de uma abordagem do metabolismo energético e do estad
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Lesur, Kupin Isabelle. "Study of the transcriptome of the prematurely aging dna2-1 yeast mutant using a new system allowing comparative DNA microarray analysis." Bordeaux 1, 2005. http://www.theses.fr/2005BOR12976.

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Cette these decrit une methode originale de comparaison automatique d'experiences de transcriptome appliquee a la determination des causes du vieillissement de l'organisme eucaryote modele: Saccharomyces cerevisiae. Les experiences de transcriptome, qui peuvent etre realisees a l'aide de microarrays, permettent au biologiste d'etudier simultanement les variations globales d'expression de milliers de genes dans de nombreuses conditions experimentales. Ces experiences a grande echelle realisees a haut-debit generent une quantite importante de donnees. En consequence, les biologistes ont besoin d
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Livres sur le sujet "Saccharomyces cerevisiae, healthy aging"

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Sing, Cierra Nicole. Aging Actin' Up: A novel aging determinant regulates the actin cytoskeleton, nutrient sensing, and lifespan in Saccharomyces cerevisiae. [publisher not identified], 2021.

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Chapitres de livres sur le sujet "Saccharomyces cerevisiae, healthy aging"

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Longo, Valter D., and Paola Fabrizio. "Chronological Aging in Saccharomyces cerevisiae." In Aging Research in Yeast. Springer Netherlands, 2011. http://dx.doi.org/10.1007/978-94-007-2561-4_5.

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Hu, Jia, Min Wei, Mario G. Mirisola, and Valter D. Longo. "Assessing Chronological Aging in Saccharomyces cerevisiae." In Methods in Molecular Biology. Humana Press, 2012. http://dx.doi.org/10.1007/978-1-62703-239-1_30.

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Yu, Ruofan, Myeong Chan Jo, and Weiwei Dang. "Measuring the Replicative Lifespan of Saccharomyces cerevisiae Using the HYAA Microfluidic Platform." In Aging. Springer US, 2020. http://dx.doi.org/10.1007/978-1-0716-0592-9_1.

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Aris, John P., Laura K. Fishwick, Michelle L. Marraffini, Arnold Y. Seo, Christiaan Leeuwenburgh, and William A. Dunn. "Amino Acid Homeostasis and Chronological Longevity in Saccharomyces cerevisiae." In Aging Research in Yeast. Springer Netherlands, 2011. http://dx.doi.org/10.1007/978-94-007-2561-4_8.

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Jazwinski, S. Michal. "The genetics of aging in the yeast Saccharomyces cerevisiae." In Genetics and Evolution of Aging. Springer Netherlands, 1994. http://dx.doi.org/10.1007/978-94-017-1671-0_6.

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Gonidakis, Stavros, and Valter D. Longo. "Oxidative Stress and Aging in the Budding Yeast Saccharomyces cerevisiae." In Oxidative Stress in Aging. Humana Press, 2008. http://dx.doi.org/10.1007/978-1-59745-420-9_5.

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Sudiyani, Yanni, Muhammad Eka Prastya, Roni Maryana, Eka Triwahyuni, and Muryanto. "The Budding Yeast Saccharomyces cerevisiae as a Valuable Model Organism for Investigating Anti-Aging Compounds." In Saccharomyces. IntechOpen, 2021. http://dx.doi.org/10.5772/intechopen.96662.

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Saccharomyces cerevisiae, the budding yeast was long history as industrial baker’s yeast due to its ability to produce numerous product such as ethanol, acetate, industrial bakers etc. Interestingly, this yeast was also important tools for studying biological mechanism in eukaryotic cells including aging, autophagy, mitochondrial response etc. S. cerevisiae has arisen as a powerful chemical and genetic screening platform, due to a rapid workflow with experimental amenability and the availability of a wide range of genetic mutant libraries. Calorie restriction (CR) as the reduction of nutrients
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Schulze, Adina, Andreas Zimmermann, Katharina Kainz, et al. "Assessing chronological aging in Saccharomyces cerevisiae." In Methods in Cell Biology. Elsevier, 2023. http://dx.doi.org/10.1016/bs.mcb.2022.09.006.

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Cadou, Angela, and Andreas Mayer. "The Nucleus-Vacuole Junction in Saccharomyces cerevisiae." In Autophagy: Cancer, Other Pathologies, Inflammation, Immunity, Infection, and Aging. Elsevier, 2015. http://dx.doi.org/10.1016/b978-0-12-801043-3.00003-0.

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Lin, Stephen S., Jill K. Manchester, and Jeffrey I. Gordon. "Cellular glucose sensing, energy metabolism, and aging in Saccharomyces cerevisiae." In Advances in Cell Aging and Gerontology. Elsevier, 2003. http://dx.doi.org/10.1016/s1566-3124(03)14010-2.

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Actes de conférences sur le sujet "Saccharomyces cerevisiae, healthy aging"

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Babarykin, Dmitry, Gaļina Smirnova, Svetlana Vasiļjeva, Anna Fedotova, Andrey Fedotov, and Natālija Basova. "Evaluation of the biological activity of sugar-free fractionated red beetroot juice." In 80th International Scientific Conference of the University of Latvia. University of Latvia, 2023. http://dx.doi.org/10.22364/iarb.2022.05.

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In the case of type II diabetes, the most important preventive and therapeutic effect gives a diet with a minimal amount of easily digestible carbohydrates. Vegetable juices are posi-tioned as healthy food, because of the high content of phenolic and other biologically active compounds. However, due to the high glycemic index, juices are contraindicated in obesity, and diabetes, while juices with a reduced glycemic index, are not available on the market. We have developed a technology for the fractionation of red beetroot juice based on molecular mass using ultrafiltration. The resulting fract
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