Bibliographies thématiques / Restrictions de domaine

Littérature scientifique sur le sujet « Restrictions de domaine »

Auteur : Grafiati
Publié le 25 mai 2024

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Articles de revues sur le sujet "Restrictions de domaine"

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Gélinas, René. « Évolution des dépenses pour l’achat de livres de bibliothèque dans les écoles et collèges du Québec de 1978 à 1982 ». Documentation et bibliothèques 28, no 4 (9 novembre 2018) : 147–52. http://dx.doi.org/10.7202/1053652ar.

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L’auteur étudie l’évolution des dépenses pour l’achat de volumes par les bibliothèques des secteurs primaire, secondaire et collégial à la lumière des programmes pédagogiques, et les conséquences des restrictions budgétaires et de la Loi 51 (Développement des entreprises québécoises dans le domaine du livre) sur le développement des collections dans ces bibliothèques.
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Chayma, Zouaghi. « Les restrictions au domaine de l’arbitrage relatives au contrôle de l’Etat : question de souveraineté ou d’abus ? » Studia Universitatis Babeş-Bolyai Iurisprudentia 62, no 4 (22 décembre 2017) : 181–90. http://dx.doi.org/10.24193/subbiur.62(2017).4.8.

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Hulk, Aafke, et Els Verheugd. « Accord et opérateurs nuls dans les projections adjectivales ». Revue québécoise de linguistique 23, no 2 (29 avril 2009) : 17–45. http://dx.doi.org/10.7202/603091ar.

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RÉSUMÉ Dans cet article, nous admettons que de dans la configuration de AP est la tête d’une projection fonctionnelle dont le spécifieur vide lie une variable dans une position argumentale auprès de l’adjectif. Pour être légitime, ce spécifieur vide doit trouver un antécédent quantificationnel, ce qui peut se faire par prédication ou par composition d’une chaîne. Ainsi s’expliquent les restrictions sur la distribution de de AP. Nous montrons que le système de formes logiques proposé par Dobrovie-Sorin (1993) permet de rendre compte des différentes interprétations des NPs quantifiés auxquels de AP ajoute un domaine de référence.
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Zanon, Damien, et Karine Merceron. « Le fonctionnement cognitif et le travail chez les personnes souffrant de troubles du spectre schizophrénique : l’apport de la Classification internationale du fonctionnement ». Santé mentale au Québec 42, no 2 (16 novembre 2017) : 71–85. http://dx.doi.org/10.7202/1041915ar.

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Cet article dresse un état des lieux de l’implication du fonctionnement cognitif dans le champ de l’insertion professionnelle et du maintien en emploi des personnes qui souffrent de troubles du spectre schizophrénique (TSS). L’objectif est de visualiser comment les déficits cognitifs s’articulent avec les autres dimensions du handicap rapportées dans la Classification internationale du fonctionnement, du handicap et de la santé (CIF), dans le domaine du travail. Les données de la littérature vont dans le sens du modèle de la CIF, à savoir un plus fort impact du fonctionnement cognitif sur les limitations d’activités (LA) plutôt que sur les restrictions de participation (RP). Ce sont en effet davantage les facteurs environnementaux et personnels qui prédisent la participation au travail. En conclusion, ce cadre théorique offre de nouvelles perspectives, notamment que la prise en compte de l’interaction entre les déficits cognitifs et les limitations d’activités peut venir étayer l’accompagnement vers et dans l’emploi des personnes souffrant de TSS.
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Rosenthal, Carolyn J. « Joseph W. Lella, with J.Z. Czank, J. McKay, and J.R. Bayne, The Perils of Patient Government : Professionals and Patients in a Chronic Care Hospital, Waterloo, Ontario : Wilfrid Laurier University press, 1986, 232 pp., $CDN 11.95 ». Canadian Journal on Aging / La Revue canadienne du vieillissement 8, no 4 (1989) : 390–93. http://dx.doi.org/10.1017/s0714980800008643.

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RÉSUMÉCe livre décrit et éxamine une étude qui avait pour but de promouvoir l'autonomie des patients en instaurant un “gouvernement de patients” dans un hôpital d'anciens combattants. À un niveau plus abstrait, l'ouvrage représente l'étude sociologique de démarches prises dans le but d'introduire des changements au sein d'un centre de soins à long terme. En première partie les auteurs font la chronique de la vie quotidienne telle qu'elle se déroule dans les pavilions, avant l'étude. La deuxième partie rend compte du mûrissement du projet et des changements nécéssaires pour procéder à la phase de réalisation. En troisième partie, les auteurs réfléchissent au sort de l'étude. En dépit des multiples problèmes qui ont gêné la réussite de l'étude, la majorité des patients en out tiré profit.Cependant elle n'a pas réussi à changer “la texture de quotidien des patients” (p. 85).Le dernier chapitre soulève des questions qui continuent de causer des problèmes en soins chroniques, notamment comment réussir à offrir un traitement personnel tout en pratiquant à l'intérieur d'un modèle médical chargé de restrictions organisationnelles propres à la plupart des hôpitaux. Le livre est une étude qualitative facile à lire qui dépeint le monde hospitalier dans toute sa complexité son personnel et ses patients. Le lecteur comprendra plus profondément la nécéssité d'introduire des changements et les obstacles qui les bloquent. Ce livre s'adresse aux professionnels dans le domaine de la santé, particulièrement aux infirmières, aux sociologues oeuvrant dans le domaine de la santé et aux étudiants qui s'intéressent à ce sujet.
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Desjardins, Marie-Claude, et Finn Makela. « La computation des délais prévus par le Code du travail ». Les Cahiers de droit 58, no 3 (12 septembre 2017) : 457–515. http://dx.doi.org/10.7202/1041009ar.

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L’objectivation du temps est importante pour plusieurs domaines de droit, et cela est particulièrement vrai pour le droit du travail. Dans le domaine du droit des rapports collectifs du travail notamment, la question précise des délais et de leur computation joue un rôle crucial, à tout le moins en Amérique du Nord, où la législation, inspirée de la Wagner Act, impose des limites importantes, du point de vue du temps, à l’exercice des droits qu’elle confère. Ces restrictions temporelles ne sont pas que de mécanismes procéduraux nécessaires à la mise en oeuvre du système : elles en sont plutôt des éléments substantiels. Les acteurs du monde du travail sont aux prises quotidiennement avec les délais prévus dans le Code du travail du Québec. En effet, ce dernier prévoit des moments précis pour l’acquisition, l’exercice et l’extinction des droits des employeurs, des syndicats et des salariés. Les règles relatives à la computation des délais sont complexes et font fréquemment l’objet de controverses jurisprudentielles. Or, jusqu’à présent, la doctrine s’est peu intéressée à la computation des délais en droit du travail québécois, malgré son importance. L’article qui suit constitue une étude exhaustive des fondements des règles de computation des délais et de leur mise en oeuvre dans le contexte du Code du travail. La première partie permet d’exposer les sources des règles applicables à la computation des délais et les concepts clés qui facilitent leur mise en oeuvre. La seconde partie s’intéresse à l’application de ces règles à des situations concrètes, en particulier dans le contexte de l’accréditation, de l’acquisition du droit de grève ou de lock-out et de recours fondés sur le Code du travail ou sur une convention collective.
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Finn, Suki. « The Role of Existential Quantification in Scientific Realism ». Philosophy 92, no 3 (17 avril 2017) : 351–67. http://dx.doi.org/10.1017/s0031819117000031.

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AbstractScientific realism holds that the terms in our scientific theories refer and that we should believe in their existence. This presupposes a certain understanding of quantification, namely that it is ontologically committing, which I challenge in this paper. I argue that the ontological loading of the quantifiers is smuggled in through restricting the domains of quantification, without which it is clear to see that quantifiers are ontologically neutral. Once we remove domain restrictions, domains of quantification can include non-existent things, as they do in scientific theorizing. Scientific realism would therefore require redefining without presupposing a view of ontologically committing quantification.
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Savage, Larry, et Chantal Mancini. « Strategic Electoral Dilemmas and the Politics of Teachers’ Unions in Ontario ». Canadian Political Science Review 16, no 1 (6 avril 2022) : 1–21. http://dx.doi.org/10.24124/c677/20221832.

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AbstractThis article seeks to explain both convergence and divergence in Ontario teacher union electoral strategy. After coalescing around a strategy of anti-Progressive Conservative (PC) strategic voting beginning with the 1999 provincial election, Ontario’s major teachers’ unions developed an electoral alliance with the McGuinty Liberals designed to advance teacher union priorities and mitigate the possibility of a return to power for the PCs. The authors use campaign finance and interview data to demonstrate that this ad hoc partnership was strengthened over the course of several election campaigns before the Liberal government’s decision to legislate restrictions on teacher union collective bargaining rights in 2012 led to unprecedented tension in the union-party partnership. The authors adapt the concept of union-party loyalty dilemmas to explain why individual teachers’ unions responded differently to the Liberal government’s efforts to impose austerity measures in the education sector.RésuméCet article vise à expliquer les convergences et divergences au sein des stratégies électorales des syndicats enseignants en Ontario. Après s’être ralliés à une approche de vote stratégique contre le Parti progressiste-conservateur (PPC) à partir des élections provinciales de 1999, les principaux syndicats enseignants de l’Ontario ont par la suite développé une alliance électorale avec les Libéraux de McGuinty afin de faire avancer leurs revendications et éviter un retour au pouvoir du PPC. Les auteurs s’appuient sur des données de financement des campagnes électorales ainsi que des entrevues afin de démontrer que ce partenariat ponctuel a été renforcé au cours de plusieurs campagnes électorales jusqu’à la décision du gouvernement libéral de faire adopter, en 2012, des restrictions aux droits de négociation collective des syndicats enseignants, conduisant ainsi à des tensions inédites au sein de cette alliance syndicats-parti. Les auteurs adaptent le concept de dilemmes de loyauté syndicat-parti afin d’expliquer pourquoi des syndicats enseignants ont répondu différemment aux efforts du gouvernement libéral d’imposer des mesures d’austérité dans le domaine de l’éducation.Keywords: unions; education; elections; Ontario; strategic votingMot-clés : syndicats; éducation; élections; Ontario; vote stratégique
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Owens, Christopher M., Byeongwoon Song, Michel J. Perron, Peter C. Yang, Matthew Stremlau et Joseph Sodroski. « Binding and Susceptibility to Postentry Restriction Factors in Monkey Cells Are Specified by Distinct Regions of the Human Immunodeficiency Virus Type 1 Capsid ». Journal of Virology 78, no 10 (15 mai 2004) : 5423–37. http://dx.doi.org/10.1128/jvi.78.10.5423-5437.2004.

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ABSTRACT In cells of Old World and some New World monkeys, dominant factors restrict human immunodeficiency virus type 1 (HIV-1) infections after virus entry. The simian immunodeficiency virus SIVmac is less susceptible to these restrictions, a property that is determined largely by the viral capsid protein. For this study, we altered exposed amino acid residues on the surface of the HIV-1 capsid, changing them to the corresponding residues found on the SIVmac capsid. We identified two distinct pathways of escape from early, postentry restriction in monkey cells. One set of mutants that were altered near the base of the cyclophilin A-binding loop of the N-terminal capsid domain or in the interdomain linker exhibited a decreased ability to bind the restricting factor(s). Consistent with the location of this putative factor-binding site, cyclophilin A and the restricting factor(s) cooperated to achieve the postentry block. A second set of mutants that were altered in the ridge formed by helices 3 and 6 of the N-terminal capsid domain efficiently bound the restricting factor(s) but were resistant to the consequences of factor binding. These results imply that binding of the simian restricting factor(s) is not sufficient to mediate the postentry block to HIV-1 and that SIVmac capsids escape the block by decreases in both factor binding and susceptibility to the effects of the factor(s).
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Myers, Scott, et Jaye Padgett. « Domain generalisation in artificial language learning ». Phonology 31, no 3 (décembre 2014) : 399–433. http://dx.doi.org/10.1017/s0952675714000207.

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Many languages have restrictions on word-final segments, such as a requirement that any word-final obstruent be voiceless. There is a phonetic basis for such restrictions at the ends of utterances, but not the ends of words. Historical linguists have long noted this mismatch, and have attributed it to an analogical generalisation of such restrictions from utterance-final to word-final position. To test whether language learners actually generalise in this way, two artificial language learning experiments were conducted. Participants heard nonsense utterances in which there was a restriction on utterance-final obstruents, but in which no information was available about word-final utterance-medial obstruents. They were then tested on utterances that included obstruents in both positions. They learned the pattern and generalised it to word-final utterance-medial position, confirming that learners are biased toward word-based distributional patterns.
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Thèses sur le sujet "Restrictions de domaine"

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Tydrichová, Magdaléna. « Structural and algorithmic aspects of preference domain restrictions in collective decision making : contributions to the study of single-peaked and Euclidean preferences ». Electronic Thesis or Diss., Sorbonne université, 2023. http://www.theses.fr/2023SORUS048.

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Cette thèse étudie des aspects structurels et algorithmiques des restrictions de domaines de préférences, en se focalisant sur les préférences unimodales et les préférences Euclidiennes. Dans la première partie de la thèse, nous introduisons d'abord une généralisation des préférences unimodales sur des graphes quelconques, en se focalisant sur des aspects algorithmiques, notamment le problème de reconnaissance. Dans un deuxième temps, nous nous intéressons aux préférences presque unimodales. Plus précisément, nous proposons une nouvelle métrique d'unimodalité approchée et nous étudions ses propriétés théoriques et computationnelles. La deuxième partie de la thèse est consacrée à l'étude des préférences d-Euclidiennes (où d est la dimension) par rapport à différentes normes. Nous proposons d'abord une heuristique de reconnaissance des préférences 2-Euclidiennes par rapport à la norme l_2, et étudions son efficacité en pratique. Enfin, nous étudions des aspects structurels des préférences 2-Euclidiennes par rapport à la norme l_1
This thesis studies structural and algorithmic aspects of preference domain restrictions, namely single-peaked preferences and Euclidean preferences. In the first part of the thesis, we first introduce a generalization of the notion of single-peakedness on an arbitrary graph. We focus, in particular, on algorithmic aspects, namely the problem of recognition. The notion of nearly single-peakedness is then studied. More precisely, we introduce a new metric of nearly single-peakedness, and we study its theoretical and computational properties. The second part of the thesis is devoted to the study of d-Euclidean preferences (where d is the dimension of the real space) with respect to different norms. We first propose a heuristic algorithm for recognizing 2-Euclidean preferences with respect to the l_2 norm, and study its practical efficiency in practice. Finally, we focus on structural aspects of 2-Euclidean preferences with respect to the l_1 norm
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Pagin, Peter. « Vagueness and Domain Restriction ». Stockholms universitet, Filosofiska institutionen, 2011. http://urn.kb.se/resolve?urn=urn:nbn:se:su:diva-68416.

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This paper develops an idea of saving ordinary uses of vague predicates from the Sorites by means of domain restriction. A tolerance level for a pred- icate, along a dimension, is a difference with respect to which the predicate is semantically insensitive. A central gap for the predicate+dimension in a domain is a segment of an associated scale, larger than this difference, where no object in the domain has a measure, and such that the extension of the predicate has measures on one side of the gap and the anti-extension on the other. The domain restriction imposes a central gap.

Author count: 1;


Vagueness and Context Factors
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Gann, Alexander Anthony Frank. « Recognition domains of type I restriction enzymes ». Thesis, University of Edinburgh, 1988. http://hdl.handle.net/1842/13875.

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Kelleher, Julia E. « Defining domains of the EcoK methylase by mutational analyses and DNA sequence comparisons ». Thesis, University of Edinburgh, 1990. http://hdl.handle.net/1842/12342.

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Chung, Ho Ryun. « The zinc finger associated domain of Drosophila melanogaster, its evolution and phylogenetic restriction ». [S.l. : s.n.], 2005. http://deposit.ddb.de/cgi-bin/dokserv?idn=974179248.

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Endriss, Cornelia, et Stefan Hinterwimmer. « The influence of tense in adverbial quantification ». Universität Potsdam, 2004. http://opus.kobv.de/ubp/volltexte/2006/840/.

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We argue that there is a crucial difference between determiner and adverbial quantification. Following Herburger [2000] and von Fintel [1994], we assume that determiner quantifiers quantify over individuals and adverbial quantifiers over eventualities. While it is usually assumed that the semantics of sentences with determiner quantifiers and those with adverbial quantifiers basically come out the same, we will show by way of new data that quantification over events is more restricted than quantification over individuals. This is because eventualities in contrast to individuals have to be located in time which is done using contextual information according to a pragmatic resolution strategy. If the contextual information and the tense information given in the respective sentence contradict each other, the sentence is uninterpretable. We conclude that this is the reason why in these cases adverbial quantification, i.e. quantification over eventualities, is impossible whereas quantification over individuals is fine.
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Martinat, Charlotte. « Rôle de la sumoylation dans les activités de SAMHD1, un facteur de restriction du VIH-1 dans les cellules non cyclantes ». Thesis, Sorbonne Paris Cité, 2018. http://www.theses.fr/2018USPCC246.

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Depuis sa découverte il y a sept ans, les recherches intensives sur SAMHD1 en ont fait un facteur cellulaire important qui limite la réplication du virus de l’immunodéficience humaine de type 1 (VIH-1) à l’étape de transcription inverse dans les cellules immunitaires non-cyclantes. Le VIH-2 et certains virus de l’immunodéficience simienne (VIS) surmontent cette restriction en exprimant la protéine Vpx, qui conduit SAMHD1 à sa dégradation protéasomique. De nombreuses données expérimentales indiquent que l’activité triphosphohydrolase (dNTPase) de SAMHD1, qui diminue les niveaux cellulaires de dNTP, est responsable de la restriction. Cependant, la seule expression de SAMHD1 ne suffit pas à rendre les cellules résistantes à l’infection par le VIH-1 et ce quel que soit le type cellulaire. De plus, il n’existe pas de corrélation stricte entre la fonction neutralisante de SAMHD1 et sa capacité à dégrader les dNTP. Il a été suggéré que la phosphorylation du résidu T592 puisse inhiber les fonctions antivirales de SAMHD1 dans les cellules en division. Cependant, l’étude de mutants phospho-mimétiques ou phospho-ablatifs mène à des résultats contradictoires. Ces données permettent d’envisager que l’activité antivirale de SAMHD1 ne repose pas exclusivement sur son activité dNTPase et que sa régulation ne peut pas être expliquée que par la phosphorylation. Nous avons démontré que SAMHD1 est modifiée par la SUMOylation, i.e. une modification post-traductionnelle consistant en la conjugaison réversible des protéines SUMO ; et avons identifié les sites principaux modifiés. Nos résultats indiquent que les mutations empêchant la SUMOylation de SAMHD1, particulièrement celle du résidu K595 adjacent au résidu phosphorylable T592, invalident sa fonction antivirale sans affecter son activité dNTPase. Un phénotype similaire est observé après suppression de la région C-terminale de SAMHD1 (résidus 595-626). Nous suggérons donc que les résidus K595 SUMOylé et T592 phosphorylé font partie d’une interface responsable du recrutement d’un co-facteur méconnu, dépendant du type cellulaire, et pouvant jouer un rôle dans le mécanisme de restriction de l’infection par le VIH-1. Notre travail permet d’entrevoir un nouvel aspect de la régulation de SAMHD1 et contribue à la caractérisation des mécanismes moléculaires sous-jacents à son pouvoir antiviral. L’identification d’un ou plusieurs partenaires cellulaires de SAMHD1 permettra de mieux comprendre le mécanisme de restriction et pourra servir de cible thérapeutique pour combattre l’infection par le VIH-1
Since its discovery seven years ago, SAMHD1 has emerged as an important cellular factor that limits the replication of the Human immunodeficiency virus type 1 (HIV-1) at the reverse transcription step in non-cycling immune cells. HIV-2 and some SIV overcome this restriction by encoding the Vpx protein, which bridges SAMHD1 to the proteasomal degradation pathway. A wealth of experimental evidence indicates that SAMHD1 triphosphohydrolase (dNTPAse) activity, which is responsible for cellular dNTP pools depletion, accounts for the premature termination of viral replication. Notably, SAMHD1 expression is not sufficient to render any tested cell type resistant to HIV-1. Besides, there is no strict link between SAMHD1 capacity to deplete dNTP pools and its neutralizing function. Phosphorylation of residue T592 is proposed to downregulate the antiviral function of SAMHD1 in cycling cells. However, the analysis of phosphomimetic or unphosphorytable mutants of SAMHD1 leads to contradictory results. Altogether, these data suggest that SAMHD1-mediated restriction may neither exclusively rely on its dNTPase activity, nor solely depend on the phosphorylation status of T592.We have demonstrated that SAMHD1 undergoes SUMOylation, i.e. a post-translational modification consisting in the reversible conjugation of SUMO on a target protein; and have identified the major sites of modification. Our results show that mutations preventing SAMHD1 SUMOylation, in particular at residue K595 that lies close to the phosphorytable T592 site, inhibit its antiviral properties without impairing its dNTPase activity. Notably, an analogous phenotype is observed upon deletion of SAMHD1 C-terminus (Δ595-626). Based on these data, we speculate that phosphorytable T592 and SUMOylated K595 residues are part of an interface in SAMHD1 C-terminal tail that is responsible for the recruitment of still unknown cofactor(s) involved in the mechanism of HIV-1 infection restriction. Our work highlights a novel aspect of SAMHD1 regulation and participates to the characterization of molecular basis underlying its antiviral function. The identification of one or several cellular partners will allow a better understanding of retroviral restriction mechanism and could serve as new therapeutic targets to fight HIV-1 infection
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Pignolet-Geslin, Stéphanie. « Contributions à l'analyse de l'agrégation de préférences floues sur des domaines économiques ». Caen, 2003. http://www.theses.fr/2003CAEN0610.

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Suite au théorème d'Arrow (1963), l'une des voies de recherche envisagées a été de modifier les conditions posées : remise en cause de la condition de domaine universel par exemple (Black (1948), Kalai, Muller et Satterthwaite (1979), Bordes et Le Breton (1989) ou encore Le Breton et Weymark (1996, 2002)), ou modification des hypothèses faites sur les préférences par la prise en compte de préférences floues (Barret, Pattanaik et Salles (1986, 1992), Banerjee (1994), Dutta (1994), Richardson (1998) entres autres). Néanmoins, aucun résultat positif satisfaisant n'émerge de ces voies de recherche. Cette thèse présente ces différents travaux et étudie l'agrégation de ces préférences floues lorsque le domaine est restreint à des domaines économiques
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Wu, Cheng-Yu. « HOST RESTRICTION FACTORS IN THE REPLICATION OF TOMBUSVIRUSES : FROM RNA HELICASES TO NUCLEOCYTOPLASMIC SHUTTLING ». UKnowledge, 2019. https://uknowledge.uky.edu/plantpath_etds/26.

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Positive-stranded (+)RNA viruses replicate inside cells and depend on many cellular factors to complete their infection cycle. In the meanwhile, (+)RNA viruses face the host innate immunity, such as cell-intrinsic restriction factors that could block virus replication. Firstly, I have established that the plant DDX17-like RH30 DEAD-box helicase conducts strong inhibitory function on tombusvirus replication when expressed in plants and yeast surrogate host. This study demonstrates that RH30 blocks the assembly of viral replicase complex, the activation of RNA-dependent RNA polymerase function of p92pol and viral RNA template recruitment. In addition, the features rendering the abundant plant DEAD-box helicases either antiviral or pro-viral functions in tombusvirus replication are intriguing. I found the reversion of the antiviral function of DDX17-like RH30 DEAD-box helicase and the coopted pro-viral DDX3-like RH20 helicase due to deletion of unique N-terminal domains. The discovery of the sequence plasticity of DEAD-box helicases that can alter recognition of different cis-acting elements in the viral genome illustrates the evolutionary potential of RNA helicases in the arms race between viruses and their hosts. Moreover, I discovered that Xpo1 possesses an anti-viral function and exports previously characterized cell-intrinsic restriction factors (CIRFs) from the nucleus to the replication compartment of tombusviruses. Altogether, in my PhD studies, I found plant RH30 DEAD-box helicase is a potent host restriction factor inhibiting multiple steps of the tombusvirus replication. In addition, I provided the evidence supporting that the Nterminal domain determines the functions of antiviral DDX17-like RH30 DEAD-box helicase and pro-viral DDX3-like RH20 DEAD-box helicase in tombusvirus replication. Moreover, I discovered the emerging significance of the Xpo1-dependent nuclear export pathway in tombusvirus replication.
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Navarro, Michel Platiny Assis. « Restrição de domínio, distributividade e a expressão kar em um dialeto de língua Kaingang ». Universidade de São Paulo, 2012. http://www.teses.usp.br/teses/disponiveis/8/8139/tde-13092012-095450/.

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Esta dissertação apresenta uma análise semântica, no paradigma da Semântica Formal, da (i) restrição de domínio no DP e da (ii) expressão kar, que veicula a ideia de totalidade, no dialeto paranaense da língua Kaingang, do tronco Macro-Jê, família Jê, falada nas regiões sul e sudeste do Brasil. Num primeiro momento, o artigo definido parece ter, no Kaingang Paranaense, uma distribuição não trivial: aplica-se primeiro a um determinante quantificacional e restringe, via essa combinação, o domínio do quantificador, tal como no Basco, Grego e Státimcets (Giannakidou 2003, Etxeberria 2005 e Etxeberria & Giannakidou 2009), línguas muito parecidas com o Kaingang no domínio nominal. Alguns dados, contudo, apontaram a análise em outra direção. Entendemos que certos padrões de comportamento semântico e sintático apresentado por kar nas sentenças, tal como sua neutralidade quanto à propriedade de distributividade e a possibilidade da conjunção de duas sequências de [NP+kar] sob um mesmo artigo definido (ao contrário do Basco, no qual a mesma estrutura é agramatical, sugerindo que os quantificadores universais em Basco criam um QP), são algumas das evidências que, no conjunto, dão suporte para a hipótese, defendida nesta dissertação, de que kar, no Kaingang Paranaense, parece ser um modificador - à la Lasersohn (1999) -, não tendo, por isso, uma força quantificacional própria. A função semântica de kar seria de controlar o quanto de desvio da verdade é pragmaticamente permissível. Como consequência desta análise, no Kaingang Paranaense o artigo definido não operaria sobre um determinante quantificacional, mas sim sobre um NP. O que aponta no sentido de que os artigos definidos ag/fag (os/as) no Kaingang Paranaense, em contextos em que eles co-ocorrem com kar, não perderiam a sua função max, i.e., de formadores de indivíduo a partir de um conjunto, para funcionar meramente como um operador preservador de tipo e restritor de domínio adjungido ao determinante quantificacional, como proposto por Giannakidou 2003, Etxeberria (2005) e Etxeberria & Giannakidou (2009) para o Basco e o Grego. Ag/fag continuariam sendo artigos definidos clássicos ocupando o núcleo de uma projeção DP e kar um modificador. Também discutimos brevemente algumas das vantagens e problemas de se tentar estender esta análise para o Basco, Grego e Státimcets. E, por último, investigamos o comportamento de kar na sentença, as possíveis leituras quando da sua interação com indefinidos, numerais, tipos de predicados e o operador distributivo introduzido via reduplicação verbal. Com base nos dados, nossa proposta é de que - em função de a leitura distributiva, na maioria dos exemplos, ser permitida pelos informantes somente quando houve reduplicação verbal - kar é neutro quanto à propriedade da distributividade e que o operador distributivo introduzido por reduplicação verbal tem escopo sobre todo o VP.
This dissertation presents, in the paradigm of formal semantics, a semantic analysis of both (i) the phenomenon of domain restriction in the DP and (ii) the expression kar, which conveys the idea of totality, in a dialect of the Kaingang language, a Brazilian language from the Macro-Jê Stock, Jê family, spoken in southern and southeastern Brazil. Although, at first, the definite article in Kaingang seems to have a non-trivial distribution: it applies first to a quantificational expression, and via such combination restricts the domain of quantifier, such as in Basque, Greek and Státimcets (Giannakidou 2003, Etxeberria 2005 and Etxeberria & Giannakidou 2009), some data pointed the analysis in another direction. Patterns of semantic and syntactic bevavior presented by kar in some sentences, such as its neutralite regarding the property of distributivity and the possibility of conjoining two [NP + kar] sequences under the same definite article (unlike Basque, which does not allow such structure, suggesting that in Basque the universal quantifier creats a QP), seem to be as a whole evidences for the hypothesis, advocated in this thesis, that the expression kar may be a modifier - à la Lasersohn (1999) - and as such would not have a quantificational force of its own. The semantic function of kar would be to control how much deviation from the truth conditions of the sentences is pragmatically allowed. As a result of this analysis, the definite articles ag/fag in Kaingang do not operate on a quantificational expression, as in Basque and Greek, but on the NP. Such fact suggests that the definite articles in Kaingang, in contexts they co-occur with kar, do not lose their max function in order to work merely as a type preserver and a domain restrictor combined with a quantificational expression, as proposed by Giannakidou 2003, Etxeberria (2005) e Etxeberria & Giannakidou (2009) for Basque and Greek. Ag/fag would still be a classical definite article occupying the head of a DP projection and kar a modifier, instead of a universal quantifier. We also discuss briefly some of the advantages and problems of trying to extend this analysis to the Basque, Greek and Státimcets languages. And lastly, we investigated the behavior of kar in the sentence, its interaction with indefinites, numerals, types of predicates and the distributive operator introduced via verbal reduplication. Based on such data, once distributive readings were permitted by the informants only via verbal reduplication, our proposal is that kar is neutral regarding the property of distributivity and that the distributive operator introduced via verbal reduplication has scope over the VP.
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Livres sur le sujet "Restrictions de domaine"

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United States. Congress. House. Committee on Resources. Trends in federal landownership and management : Hearing before the Committee on Resources, House of Representatives, One Hundred Fourth Congress, first session, on the effect that federal ownership and management of public lands and the condemnation and restriction of private property has on local areas, March 2, 1995--Washington, DC. Washington : U.S. G.P.O., 1995.

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United States. Congress. House. Committee on Resources. Trends in federal landownership and management : Hearing before the Committee on Resources, House of Representatives, One Hundred Fourth Congress, first session, on the effect that federal ownership and management of public lands and the condemnation and restriction of private property has on local areas, March 2, 1995--Washington, DC. Washington : U.S. G.P.O., 1995.

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Breckenridge, Wylie. Implicit Domain Restriction. Oxford University Press, 2018. http://dx.doi.org/10.1093/oso/9780199600465.003.0006.

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According to the proposal made in Chapter 4, we use ‘grey’ in ‘The patch looks grey to you’ to refer to a way of looking by quantifying over events. When we quantify it is very common for us to implicitly restrict the domain of things over which we do so. The author proposes that, as an instance of this general phenomenon, we employ implicit domain restriction when we use ‘grey’ to quantify over events in ‘The patch looks grey to you’. The author uses this to explain various phenomena to do with our use of ‘grey’ and other adjectives in ‘look’ sentences.
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Jónsson, Jóhannes Gísli, et Thórhallur Eythórsson, dir. Syntactic Features and the Limits of Syntactic Change. Oxford University Press, 2021. http://dx.doi.org/10.1093/oso/9780198832584.001.0001.

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This volume brings together the latest diachronic research on syntactic features and their role in restricting syntactic change. The chapters address a central theoretical issue in diachronic syntax: whether syntactic variation can always be attributed to differences in the features of items in the lexicon, as the Borer-Chomsky conjecture proposes. In answering this question, all the chapters develop analyses of syntactic change couched within a formalist framework in which rich hierarchical structures and abstract features of various kinds play an important role. The first three parts of the volume explore the different domains of the clause, namely the C-domain, the T-domain and the ν‎P/VP-domain respectively, while chapters in the final part are concerned with establishing methodology in diachronic syntax and modelling linguistic correspondences. The contributors draw on extensive data from a large number of languages and dialects, including several that have received little attention in the literature on diachronic syntax, such as Romeyka, a Greek variety spoken in Turkey, and Middle Low German, previously spoken in northern Germany. Other languages are explored from a fresh theoretical perspective, including Hungarian, Icelandic, and Austronesian languages. The volume sheds light not only on specific syntactic changes from a cross-linguistic perspective but also on broader issues in language change and linguistic theory.
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Linnebo, Øystein. Dynamic Abstraction. Oxford University Press, 2018. http://dx.doi.org/10.1093/oso/9780199641314.003.0003.

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Any abstractionist approach to thin objects faces the threat of paradox, as illustrated by Frege’s inconsistent Basic Law V. The neo-Fregeans Hale and Wright respond by severely restricting the class of acceptable abstraction principles. Their approach is static in the sense that they hold the domain fixed. This approach to abstraction is criticized, and an alternative approach is developed which permits abstraction on a vast class of equivalence relations. This alternative approach is dynamic in the sense that abstraction on an extensionally specified domain (i.e. a domain specified by means of a plurality of objects) may result in a larger such domain. A form of absolute generality is nevertheless possible, provided that the associated domain is understood in an intensional sense (i.e. it cannot be specified by means of a plurality).
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Sekaran, Nishant K., et Theodore J. Iwashyna. Patterns of Recovery after Critical Illness. Oxford University Press, 2014. http://dx.doi.org/10.1093/med/9780199653461.003.0006.

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There are at least as many ways to recover from critical illness as there are to become critically ill. This chapter argues that, to understand recovery, we need to understand both its trajectory and the different domains in which recovery occurs. An adequate description of recovery should include pre-illness characteristics, depth of problems during the acute illness, the rate and duration of recovery, the extent of peak recovery, and long-term differences in post-illness trajectory. It should also take seriously the distinct domains mapped out in the World Health Organization’s International Classification of Functioning (ICF): tissue impairment, activity limitations, participation restriction, and health-related quality of life. These domains each represent distinct and important facets, and separately assessing each leads to deeper understanding and opportunities for intervention.
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Ferstman, Carla. Challenging the Conduct of International Organizations before Domestic Courts. Oxford University Press, 2017. http://dx.doi.org/10.1093/oso/9780198808442.003.0006.

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This chapter is about domestic courts. Victims often have no other option than to seek a remedy against an international organization before domestic courts. This is so even though the domestic character of such courts does not lend well to them playing this particular adjudicative role with regard to disputes concerning international organizations and organizational immunities from the jurisdiction of domestic courts are near absolute. Unlike the progressive recognition of restrictions to the immunity of States and their agents, there have been only limited parallel developments in the domain of organizational immunity. The chapter considers the extent of immunities and other jurisdictional bars before domestic courts and considers the practice of international organizations to waive immunity.
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Hanson, Ardis, Carol A. Ott et Bruce Lubotsky Levin. Behavioral Health. Oxford University Press, 2018. http://dx.doi.org/10.1093/med/9780190238308.003.0008.

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Seven of the top 20 disorders affecting morbidity are mental illnesses: major depressive disorders, drug use disorders, anxiety disorders, alcohol use disorders, schizophrenia, bipolar disorder, and dysthymia. Behavioral health disorders are important determinants of work role disability and quality of life. Behavioral health disorders also have generally stronger “cross-domain” effects, exacerbating the diagnosis and treatment of many physical disorders and chronic medical conditions. In addition to the persistent stigma surrounding behavioral health disorders, there are issues of reimbursement, costs of care, availability of care based on provider and/or geographic availability, policy limitations, formulary restrictions, transportation, provider knowledge, patient knowledge, attitudinal/evaluative barriers, medication compliance, family support (or lack of it), inconvenience or inability to obtain an appointment, and refusal of treatment. This chapter provides an overview of the issues surrounding behavioral health care from a population health perspective, including pharmaceutical treatment and competencies for community-based pharmacists.
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Mahajan, Anoop. Accusative and Ergative in Hindi. Sous la direction de Jessica Coon, Diane Massam et Lisa Demena Travis. Oxford University Press, 2017. http://dx.doi.org/10.1093/oxfordhb/9780198739371.013.4.

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This chapter examines the nature of case licensing of the direct object in ergative constructions in Hindi, a split ergative language. Split ergativity in Hindi is conditioned by aspect – perfective transitive constructions display ergative case marking while non-perfective clauses do not. The chapter argues that in Hindi the morphologically bare direct object in an ergative construction is case licensed by T(ense) and not by little v as argued recently by Legate (2008) and others. The evidence for this proposal comes from examining the syntax of perfective and imperfective prenominal relative clauses, an empirical domain in Hindi that has not been previously examined from the perspective of case licensing. The restrictions found on what arguments can be relativized in prenominal relative clauses provide crucial evidence for the nature of case licensing in Hindi participial clauses and that evidence in turn bears upon the nature of object case licensing in ergative constructions.
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Marano, Christopher M. Driving Considerations in Cognitive Impairment and Depression in Older Patients. Oxford University Press, 2017. http://dx.doi.org/10.1093/med/9780199959549.003.0008.

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Cognitive impairment can impair driving skills and safety, and given the fact that persons with MCI can develop cognitive deficits in several cognitive domains it is important to address driving safety. The goal of the clinician is to identify potentially unsafe drivers without unnecessarily restricting safe drivers, and this chapter focuses on evaluating patients in this gray area. The office exam can be be broadened to address cognitive and functional assessments that may reflect on driving safety, and the clinician may advise the patient and family to have a comprehensive driving assessment by a driving rehabilitation specialist. Clinicians need to be well informed about state law regarding the evaluation of driving safety in order to maintain privacy while adhering to highest standards of public safety.
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Chapitres de livres sur le sujet "Restrictions de domaine"

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Mayer, Rolf. « Anaphora and domain restriction ». Dans Text Understanding in LILOG, 297–312. Berlin, Heidelberg : Springer Berlin Heidelberg, 1991. http://dx.doi.org/10.1007/3-540-54594-8_66.

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Pagin, Peter. « Vagueness and Domain Restriction ». Dans Vagueness and Language Use, 283–307. London : Palgrave Macmillan UK, 2011. http://dx.doi.org/10.1057/9780230299313_13.

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Roberts, Craige. « Domain Restriction in Dynamic Semantics ». Dans Quantification in Natural Languages, 661–700. Dordrecht : Springer Netherlands, 1995. http://dx.doi.org/10.1007/978-94-011-0321-3_20.

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Roberts, Craige. « Domain Restriction in Dynamic Semantics ». Dans Quantification in Natural Languages, 661–700. Dordrecht : Springer Netherlands, 1995. http://dx.doi.org/10.1007/978-94-017-2817-1_20.

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Plump, Christina, Bernhard J. Berger et Rolf Drechsler. « Choosing the Right Technique for the Right Restriction – A Domain-Specific Approach for Enforcing Search-Space Restrictions in Evolutionary Algorithms ». Dans Dynamics in Logistics, 349–59. Cham : Springer International Publishing, 2022. http://dx.doi.org/10.1007/978-3-031-05359-7_28.

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Barberà, Salvador, Dolors Berga et Bernardo Moreno. « Some New Domain Restrictions in Social Choice, and Their Consequences ». Dans Modeling Decisions for Artificial Intelligence, 11–24. Berlin, Heidelberg : Springer Berlin Heidelberg, 2013. http://dx.doi.org/10.1007/978-3-642-41550-0_2.

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Schwarz, Florian. « Definites, Domain Restriction, and Discourse Structure in Online Processing ». Dans Grammatical Approaches to Language Processing, 187–208. Cham : Springer International Publishing, 2019. http://dx.doi.org/10.1007/978-3-030-01563-3_10.

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É. Kiss, Katalin, et Tamás Zétényi. « Scalar Implicature or Domain Restriction : How Children Determine the Domain of Numerical Quantifiers ». Dans Linguistic and Cognitive Aspects of Quantification, 83–114. Cham : Springer International Publishing, 2018. http://dx.doi.org/10.1007/978-3-319-91566-1_5.

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Efthymiou, Angeliki. « Chapter 6. Diminutive formation in Modern Greek ». Dans Linguistik Aktuell/Linguistics Today, 176–205. Amsterdam : John Benjamins Publishing Company, 2024. http://dx.doi.org/10.1075/la.284.06eft.

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The aim of this chapter is to investigate variation in Modern Greek diminutive derivational means (affixes and affixoids) by focusing on their selectional restrictions (e.g. phonological, morphological, semantic) and their competition (e.g. psilo.xondrós ‘dim.fat’ vs. xondr.oúlis ‘fat.dim’). Given that the use of all Greek diminutive morphemes (affixes or affixoids) is subject to selectional restrictions, it is shown that the variation found in diminutive derivational morphemes can be explained with reference to their particular restrictions and their multifunctional character. Furthermore, it is demonstrated that the domain of Modern Greek diminutive morphemes can be thought of as a complex ecosystem structured around a fairly complementary distribution (rather than competition).
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Ell, Basil, Sherzod Hakimov et Philipp Cimiano. « Statistical Induction of Coupled Domain/Range Restrictions from RDF Knowledge Bases ». Dans Lecture Notes in Computer Science, 27–40. Cham : Springer International Publishing, 2017. http://dx.doi.org/10.1007/978-3-319-68723-0_3.

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Actes de conférences sur le sujet "Restrictions de domaine"

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Eiben, Eduard, Robert Ganian, Dušan Knop et Sebastian Ordyniak. « Unary Integer Linear Programming with Structural Restrictions ». Dans Twenty-Seventh International Joint Conference on Artificial Intelligence {IJCAI-18}. California : International Joint Conferences on Artificial Intelligence Organization, 2018. http://dx.doi.org/10.24963/ijcai.2018/179.

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Recently a number of algorithmic results have appeared which show the tractability of Integer Linear Programming (ILP) instances under strong restrictions on variable domains and/or coefficients (AAAI 2016, AAAI 2017, IJCAI 2017). In this paper, we target ILPs where neither the variable domains nor the coefficients are restricted by a fixed constant or parameter; instead, we only require that our instances can be encoded in unary. We provide new algorithms and lower bounds for such ILPs by exploiting the structure of their variable interactions, represented as a graph. Our first set of results focuses on solving ILP instances through the use of a graph parameter called clique-width, which can be seen as an extension of treewidth which also captures well-structured dense graphs. In particular, we obtain a polynomial-time algorithm for instances of bounded clique-width whose domain and coefficients are polynomially bounded by the input size, and we complement this positive result by a number of algorithmic lower bounds. Afterwards, we turn our attention to ILPs with acyclic variable interactions. In this setting, we obtain a complexity map for the problem with respect to the graph representation used and restrictions on the encoding.
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Fu, Yaosheng, Tri M. Nguyen et David Wentzlaff. « Coherence domain restriction on large scale systems ». Dans MICRO-48 : The 48th Annual IEEE/ACM International Symposium of Microarchitecture. New York, NY, USA : ACM, 2015. http://dx.doi.org/10.1145/2830772.2830832.

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Schleicher, Daniel, Christoph Fehling, Stefan Grohe, Frank Leymann, Alexander Nowak, Patrick Schneider et David Schumm. « Compliance Domains : A Means to Model Data-Restrictions in Cloud Environments ». Dans 2011 15th IEEE International Enterprise Distributed Object Computing Conference (EDOC 2011). IEEE, 2011. http://dx.doi.org/10.1109/edoc.2011.22.

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Riahi, Reza, Farshid Bagheri et Bijan Farhanieh. « Experimental and Numerical Investigation of Fluid Dynamics of the Bounded and Unbounded Triangular Jets ». Dans ASME Turbo Expo 2008 : Power for Land, Sea, and Air. ASMEDC, 2008. http://dx.doi.org/10.1115/gt2008-50407.

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In the present study, the fluid characteristics of triangular turbulent jet flow are considered experimentally and numerically. The results of spatially developed three-dimensional jet, issued from an equilateral triangular nozzle are presented. The jet is discharged to both bounded and unbounded domains. Because of the wind tunnel set up restrictions, the experimental study has done just for the bounded domain. The hot-wire anemometry is used for experimental study. A numerical method employing control volume approach with collocated grid arrangement which couples the velocity and pressure fields with SIMPLEC algorithm is introduced to discrete the governing equations of fluid flow. The turbulent stresses are approximated using k-ε model. Both bounded and unbounded domains have been studied using a numerical code. The velocity field is presented using profiles and contours. Comparison of numerical and experimental results for the bounded domain shows a good agreement. The flow pattern results show that the strong mixing and flow entrainment from free boundaries into the jet takes place and eventuates to expand the jet highly at the unbounded domain.
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Aras, Eyyup. « Investigating the Effects of Branching on the Constraint-Embedded Swept Profile Calculations ». Dans ASME 2021 International Mechanical Engineering Congress and Exposition. American Society of Mechanical Engineers, 2021. http://dx.doi.org/10.1115/imece2021-70210.

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Abstract One of the most significant issues investigated in the CAD/CAM developments is the swept envelope formation by a moving tool. There is many attempts to get envelopes, based on the evaluation of tangency constraint. The core operation of this method is to pick the input values one at a time and consider the solutions of constraint for various dependent values at a particular time instance. Such a pathway causes excessive computational effort and time that must be spent to implement the tangency constraint. Recently some research [15,17] has been conducted to completely eliminate the need for evaluating tangency-constraint. In these techniques in order to obtain a closed-form representation of the envelope, the tangency constraint is written explicitly in terms of the dependent variable then it is embedded into the tool surface equation. While these sound straight forward, there are some important inevitable consequences of these restructurings. In the new form, there are no restrictions on the domains of the input variables. On the other hand, for the form-cutting tools the whole set of input values need to be partitioned into a number of disjoint ordered-subsets for which correspondence check between domain and eliminated variables must be performed. The computational cost associated with this type of calculation can become impractical when looking at all the benefits we get from eliminating the tangency-constraint evaluation. To overcome this issue, in this paper first, we introduce a powerful test that takes the domain restrictions into account. Later, using this test we will systematically investigate the distribution patterns of swept profiles. Finally, we present algorithms for forming the domains of closed forms under different motion kinematics.
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Kimura, Fuminori, Akira Maeda, Kenji Hatano, Jun Miyazaki et Shunsuke Uemura. « Cross-Language Information Retrieval by Domain Restriction Using Web Directory Structure ». Dans 2008 41st Annual Hawaii International Conference on System Sciences. IEEE, 2008. http://dx.doi.org/10.1109/hicss.2008.108.

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AIMI, A., M. DILIGENTI et A. SALVADORI. « RESTRICTION MATRICES AND SYMMETRIC PANEL CLUSTERING METHOD FOR MULTI-DOMAIN SGBEM ». Dans Proceedings of the 7th Conference. WORLD SCIENTIFIC, 2005. http://dx.doi.org/10.1142/9789812701817_0001.

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Baader, Franz, Stefan Borgwardt et Marcel Lippmann. « Query Rewriting for DL-Lite with n-ary Concrete Domains ». Dans Twenty-Sixth International Joint Conference on Artificial Intelligence. California : International Joint Conferences on Artificial Intelligence Organization, 2017. http://dx.doi.org/10.24963/ijcai.2017/109.

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We investigate ontology-based query answering (OBQA) in a setting where both the ontology and the query can refer to concrete values such as numbers and strings. In contrast to previous work on this topic, the built-in predicates used to compare values are not restricted to being unary. We introduce restrictions on these predicates and on the ontology language that allow us to reduce OBQA to query answering in databases using the so-called combined rewriting approach. Though at first sight our restrictions are different from the ones used in previous work, we show that our results strictly subsume some of the existing first-order rewritability results for unary predicates.
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Zhou, Heyu, Weizhi Nie, Wenhui Li, Dan Song et An-An Liu. « Hierarchical Instance Feature Alignment for 2D Image-Based 3D Shape Retrieval ». Dans Twenty-Ninth International Joint Conference on Artificial Intelligence and Seventeenth Pacific Rim International Conference on Artificial Intelligence {IJCAI-PRICAI-20}. California : International Joint Conferences on Artificial Intelligence Organization, 2020. http://dx.doi.org/10.24963/ijcai.2020/117.

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2D image-based 3D shape retrieval has become a hot research topic since its wide industrial applications and academic significance. However, existing view-based 3D shape retrieval methods are restricted by two settings, 1) learn the common-class features while neglecting the instance visual characteristics, 2) narrow the global domain variations while ignoring the local semantic variations in each category. To overcome these problems, we propose a novel hierarchical instance feature alignment (HIFA) method for this task. HIFA consists of two modules, cross-modal instance feature learning and hierarchical instance feature alignment. Specifically, we first use CNN to extract both 2D image and multi-view features. Then, we maximize the mutual information between the input data and the high-level feature to preserve as much as visual characteristics of an individual instance. To mix up the features in two domains, we enforce feature alignment considering both global domain and local semantic levels. By narrowing the global domain variations we impose the identical large norm restriction on both 2D and 3D feature-norm expectations to facilitate more transferable possibility. By narrowing the local variations we propose to minimize the distance between two centroids of the same class from different domains to obtain semantic consistency. Extensive experiments on two popular and novel datasets, MI3DOR and MI3DOR-2, validate the superiority of HIFA for 2D image-based 3D shape retrieval task.
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Erickson, L. A., P. W. Bergum, E. V. Hubert, N. Y. Theriault, E. F. Rehberg, D. P. Palermo, G. A. W. deMunk, J. H. Verheijen et K. R. Marotti. « ENHANCEMENT AND INHIBITION OF THE ACTIVITY OF RECOMBINANT ANALOGS OF TISSUE PLASMINOGEN ACTIVATOR ». Dans XIth International Congress on Thrombosis and Haemostasis. Schattauer GmbH, 1987. http://dx.doi.org/10.1055/s-0038-1643844.

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Both the affinity of tissue plasminogen activator (tPA) for fibrin, which is associated with enhancement of its activity, and its susceptibility to inhibition contribute to the ability of this molecule to initiate vascular fibrinolysis. Full-length tPA is thought to consist of five structural regions designated the finger (F), growth factor-like (G), kringle 1 (K1), kringle 2 (K2), and protease (P) domains. Previous studies have suggested that the interaction of tPA with fibrin is primarily dependent upon the presence of the F and K2 domains, with its inhibition minimally requiring an intact active site. We have generated analogs of tPA with which to study further the relationship between the structure and the function of these domains. Synthetic DNA molecules, encoding specific tPA analogs and containing unique restriction sites in the interdomain regions, were expressed in Chinese hamster ovary cells. Serum-free media conditioned by transfected cells were then analyzed for both tPA antigen and activity. Analogs studied thus far include the full-length molecule FGK1K2P, GK1K2P, FK1K2P, FGK2P, FGK1P, FGK2K1P, and FK2P. In each case, samples of conditioned medium contained from 100 to 200 ng of tPA-like material per ml. Based on active-site titration of immunopurified analogs with 3H-DFP and assessment of tPA activity in the presence of CNBr-digested fibrinogen, the specific activities of analogs containing the K2 domain adjacent to the P domain were similar to that of native full-length tPA. In contrast, the specific activities of analogs with the K2 domain deleted (FGK1P) or transposed (FGK2K1P) were significantly reduced, indicative of the decreased ability of the fibrinogen fragments to enhance their respective activities. The extent of neutralization of the activity of each analog by platelet-derived PA inhibitor appeared to be similar to that of full-length tPA, confirming that the P domain contains the primary site of interaction between tPA and inhibitor. These data suggest that not only the presence of but also the position of the K2 domain are important for proper expression of tPA's activity.
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Rapports d'organisations sur le sujet "Restrictions de domaine"

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Carvajal, Andrés. Testable restrictions of Nash equilibrium in games with continuous domains. Bogotá, Colombia : Banco de la República, janvier 2003. http://dx.doi.org/10.32468/be.229.

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2

Pensel, Maximilian, et Anni-Yasmin Turhan. Making Quantification Relevant Again —the Case of Defeasible EL⊥. Technische Universität Dresden, 2017. http://dx.doi.org/10.25368/2022.231.

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Defeasible Description Logics (DDLs) extend Description Logics with defeasible concept inclusions. Reasoning in DDLs often employs rational or relevant closure according to the (propositional) KLM postulates. If in DDLs with quantification a defeasible subsumption relationship holds between concepts, this relationship might also hold if these concepts appear in existential restrictions. Such nested defeasible subsumption relationships were not detected by earlier reasoning algorithms—neither for rational nor relevant closure. In this report, we present a new approach for EL ⊥ that alleviates this problem for relevant closure (the strongest form of preferential reasoning currently investigated) by the use of typicality models that extend classical canonical models by domain elements that individually satisfy any amount of consistent defeasible knowledge. We also show that a certain restriction on the domain of the typicality models in this approach yields inference results that correspond to the (weaker) more commonly known rational closure.
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3

Baader, Franz, Stefan Borgwardt et Marcel Lippmann. Query Rewriting for DL-Lite with n-ary Concrete Domains (Extended Version). Technische Universität Dresden, 2017. http://dx.doi.org/10.25368/2022.234.

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We investigate ontology-based query answering (OBQA) in a setting where both the ontology and the query can refer to concrete values such as numbers and strings. In contrast to previous work on this topic, the built-in predicates used to compare values are not restricted to being unary. We introduce restrictions on these predicates and on the ontology language that allow us to reduce OBQA to query answering in databases using the so-called combined rewriting approach. Though at first sight our restrictions are different from the ones used in previous work, we show that our results strictly subsume some of the existing first-order rewritability results for unary predicates.
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4

Anderson, Olin, et Gad Galili. Development of Assay Systems for Bioengineering Proteins that Affect Dough Quality and Wheat Utilization. United States Department of Agriculture, 1994. http://dx.doi.org/10.32747/1994.7568781.bard.

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The quality and utilization of wheat is largely dependent upon the exact physical/chemical properties of the doughs made from flour/water mixtures. Among the wheat seed components most correlated with dough visoelastic parameters are the high-molecular-weight (HMW) glutenin subunits whose disulfide cross-linked macropolymer is critical for dough functionality. We have used the tools of molecular biology, wheat transformation, heterologous expression of HMW-glutenin subunits in bacteria, and dough micro-mixing experiments to examine some of the molecular basis of HMW-glutenin functionality. In addition, we have developed sets of modified and synthetic gene constructs and transgenic wheat lines that will allow further examination of the role of the HMW-glutenins. Among the results from this work is evidence that the HMW-glutenin repeat domain is directly related to dough properties, the demonstration that interaction between subunits is dependent upon domain presence but not order, a novel understanding of the restrictions on intra-vs inter-chain disulfide bonds, the demonstration that HMW-glutenin genes can be transformed into wheat for simultaneously high expression of the transgene and suppression of the endogenous genes, and the construction of a set of modified HMW-glutenins capable of being epitope tagged for studying polypeptide subcellular processing and the fate of HMW-glutenins in dough mixing experiments.
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5

Giles Álvarez, Laura, Juan Carlos Vargas-Moreno, Alejandra Mejía, Aastha Patel et Nerlyne Jean-Baptiste. Une approche spatiale pour analyser l’insécurité alimentaire dans le département du Nord-Ouest d’Haïti. Inter-American Development Bank, décembre 2022. http://dx.doi.org/10.18235/0004589.

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Cette étude présente une analyse de l’insécurité alimentaire et de ses facteurs sous-jacents dans le département du Nord-Ouest en Haïti. Ce département est l’un des plus vulnérable et le plus touché par l’insécurité alimentaire en Haïti, avec 55 % de la population ayant besoin d’une assistance urgente (IPC 2022). L’aide du Cadre intégré des phases de la sécurité alimentaire (IPC) et du Cadre de sécurité alimentaire (BID 2018) de la Banque Interaméricaine de développement (BID), cet article présente une analyse géo-spatiale, complétée par un examen d’autres facteurs socioéconomiques, pour donner un aperçu de ce qui aggrave cette crise alimentaire et des domaines les plus urgents à traiter. Les résultats montrent que le déclin de la production nationale - qui a été entravée par des infrastructures et des financements inadéquats, l’insécurité et les catastrophes naturelles - s’est produit parallèlement aux perturbations de la chane d’approvisionnement internationale, affectant les importations conjointement avec les recettes provenant de laide. L’ensemble de ces facteurs a un effet négatif sur la disponibilité de la nourriture. Les contraintes d’approvisionnement, les restrictions de mobilité, les chocs de prix et les risques pour les revenus durables ont également un impact négatif sur l’accès à la nourriture. Les difficultés d’accès à l’eau potable et aux infrastructures sanitaires, ainsi que le manque de diversité au niveau des régimes alimentaires, entravent également l’utilisation de la nourriture, décrite comme la disponibilité d’aliments de qualité nécessaires pour atteindre un statut nutritionnel adéquat. En outre, la stabilité alimentaire n’est pas garantie en raison des problèmes liés aux dotations naturelles de la région, au manque ou à la faible capacité des infrastructures d’irrigation, à la vulnérabilité aux chocs climatiques, aux fluctuations des prix et à l’insécurité. Sur la base de ces résultats, ce document recommande 23 actions visant à augmenter l’accès aux services de base, à promouvoir une nutrition adéquate, à soutenir une agriculture productive et durable et à accroître la résilience aux chocs et aux fluctuations inhérentes à l’écosystème alimentaire. Plus important encore, le déploiement efficace de ces mesures nécessitera une approche coordonnée à tous les niveaux administratifs de ltatocal et national, en collaboration avec le secteur privé et la communauté des donateurs.
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