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1

Fujioka, Haruna, Masato S. Abe, and Yasukazu Okada. "Individual Ants Do Not Show Activity-Rest Rhythms in Nest Conditions." Journal of Biological Rhythms 36, no. 3 (2021): 297–310. http://dx.doi.org/10.1177/07487304211002934.

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Circadian rhythms, which respond to the day-night cycle on the earth, arise from the endogenous timekeeping system within organisms, called the “biological clock.” For accurate circadian rhythms, daily fluctuations in light and temperature are considered one of the important time cues. In social insects, both abiotic and biotic factors (i.e., social interactions) play a significant role in activity-rest rhythm regulation. However, it is challenging to monitor individual activity-rest rhythms in a colony because of the large group size and small body size. Therefore, it is unclear whether indiv
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Arzola-Rodríguez, Jesús José. "Sueño y ritmos circadianos en supervivientes de falla respiratoria aguda." Kompass Neumología 3, no. 1 (2021): 14–15. http://dx.doi.org/10.1159/000513799.

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<b>Background:</b> Little is known about sleep and circadian rhythms in survivors of acute respiratory failure (ARF) after hospital discharge. <b>Objectives:</b> To examine sleep and rest-activity circadian rhythms in ARF survivors 3 months after hospital discharge, and to compare them with a community-dwelling population. <b>Methods:</b> Sleep diary, actigraphy data, and insomnia symptoms were collected in a pilot study of 14 ARF survivors. Rest-activity circadian rhythms were assessed with wrist actigraphy and sleep diary for 9 days, and were analyzed by c
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Slyepchenko, Anastasiya, Olivia R. Allega, Xiamin Leng, et al. "Association of functioning and quality of life with objective and subjective measures of sleep and biological rhythms in major depressive and bipolar disorder." Australian & New Zealand Journal of Psychiatry 53, no. 7 (2019): 683–96. http://dx.doi.org/10.1177/0004867419829228.

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Objective: Disruptions in biological rhythms and sleep are a core aspect of mood disorders, with sleep and rhythm changes frequently occurring prior to and during mood episodes. Wrist-worn actigraphs are increasingly utilized to measure ambulatory activity rhythm and sleep patterns. Methods: A comprehensive study using subjective and objective measures of sleep and biological rhythms was conducted in 111 participants (40 healthy volunteers [HC], 38 with major depressive disorder [MDD] and 33 with bipolar disorder [BD]). Participants completed 15-day actigraphy and first-morning urine samples t
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Yeung, Chris Ho Ching, Cici Bauer, and Qian Xiao. "Associations between Rest–Activity Rhythms and Liver Function Tests: The US National Health and Nutrition Examination Survey, 2011–2014." Clocks & Sleep 5, no. 4 (2023): 667–85. http://dx.doi.org/10.3390/clockssleep5040045.

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Liver functions are regulated by the circadian rhythm; however, whether a weakened circadian rhythm is associated with impaired liver function is unclear. This study aims to investigate the association of characteristics of rest–activity rhythms with abnormal levels of biomarkers of liver function. Data were obtained from the National Health and Nutrition Examination Survey 2011–2014. Seven rest–activity rhythm parameters were derived from 24 h actigraphy data using the extended cosine model and non-parametric methods. Multiple logistic regression and multiple linear regression models were use
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Dispersyn, Garance, Laure Pain, and Yvan Touitou. "Circadian Disruption of Body Core Temperature and Rest–Activity Rhythms after General (Propofol) Anesthesia in Rats." Anesthesiology 110, no. 6 (2009): 1305–15. http://dx.doi.org/10.1097/aln.0b013e3181a10225.

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Background General anesthesia is commonly associated with sleep disorders, fatigue, drowsiness, and mood alterations in patients. The authors examined whether general (propofol) anesthesia can impact the circadian temporal structure by disturbing circadian rest-activity and body temperature rhythms under normal light-dark conditions (light-dark 12:12 h) in rats. Methods A group of rats was anesthetized with propofol, and another was injected with 10% Intralipid, which was used as a control lipidic solution. The authors examined six groups of rats according to the Zeitgeber time of intraperiton
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Giannetto, C., F. Fazio, A. Assenza, G. Caola, P. Pennisi, and G. Piccione. "Circadian rhythms of redox states and total locomotor activity in dairy cattle." Czech Journal of Animal Science 55, No. 5 (2010): 183–89. http://dx.doi.org/10.17221/306/2009-cjas.

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We want to study the circadian rhythm of dROMs and anti-oxidative power in dairy cattle during dry period and the possible involvement of the circadian organization of rest/activity cycles in the fluctuation of redox state. For this purpose we recorded TLA in five clinically healthy Bruna Italian dairy cattle by means of an actigraphy-based data logger, Actiwatch-Mini<sup>®</sup>. Blood samples were collected every 3 hours over a 48-hour period for the assessment of free radicals (dROMs) and the antioxidant power: antioxidant barrier (Oxy-ads) and thiol-antioxidant barrier
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Calogiuri, Giovanna, Andi Weydahl, and Franca Carandente. "Methodological Issues for Studying the Rest–Activity Cycle and Sleep Disturbances." Biological Research For Nursing 15, no. 1 (2011): 5–12. http://dx.doi.org/10.1177/1099800411416224.

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Shift work schedules, intensive physical exercise late in the day, psychological stress, or a busy lifestyle might induce disorders of the circadian structure, which can affect health on both the physiological and neurobehavioral levels. Rest–activity rhythm is strongly connected with an organism’s circadian structure, and irregular sleep–wake patterns can lead to a disruption of entrainment, resulting in physiological and neurobehavioral dysfunction. Shift nurses are often subject to disturbances in the quality and duration of their sleep, raising the possibility of negative impacts on their
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Gander, P. H., R. Lydic, H. E. Albers, and M. C. Moore-Ede. "Forced internal desynchronization between circadian temperature and activity rhythms in squirrel monkeys." American Journal of Physiology-Regulatory, Integrative and Comparative Physiology 248, no. 5 (1985): R567—R572. http://dx.doi.org/10.1152/ajpregu.1985.248.5.r567.

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In an attempt to force internal desynchronization between the rest-activity rhythm and the body temperature rhythm of the squirrel monkey (Saimiri sciureus), five animals were studied in a 14:14 light-dark cycle. In four animals a 28-h spectral component was found to predominate in the rest-activity rhythm, whereas an unentrained circadian component (tau = 25.9 +/- 0.4 h) predominated in the body temperature rhythm. Plots of the cycle-by-cycle acrophases of the two rhythms confirm that they desynchronize, due to the failure of the temperature rhythm to entrain to the light-dark cycle. These da
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Kim, Minjee, Kathryn Reid, Matthew Maas, et al. "164 Greater Light Exposure Is Associated with More Robust Rest-Activity Rhythms in Community-Dwelling Older Adults." Sleep 44, Supplement_2 (2021): A67. http://dx.doi.org/10.1093/sleep/zsab072.163.

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Abstract Introduction Disrupted circadian rest-activity rhythms in older adults have been associated with an increased risk of cognitive decline and mortality. While light is one of the most potent synchronizing agents for the human circadian system, little is known about how light may influence rest-activity rhythms in older adults. We aimed to investigate the relationship between the amount of light exposure and rest-activity rhythm parameters using actigraphy data from a large cohort study. Methods 553 community-dwelling older adults (aged 72±5, 142 (25.5%) female) from the Chicago Healthy
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Brown, Laurence, Angus Fisk, Carina Pothecary, and Stuart Peirson. "Telling the Time with a Broken Clock: Quantifying Circadian Disruption in Animal Models." Biology 8, no. 1 (2019): 18. http://dx.doi.org/10.3390/biology8010018.

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Circadian rhythms are approximately 24 h cycles in physiology and behaviour that enable organisms to anticipate predictable rhythmic changes in their environment. These rhythms are a hallmark of normal healthy physiology, and disruption of circadian rhythms has implications for cognitive, metabolic, cardiovascular and immune function. Circadian disruption is of increasing concern, and may occur as a result of the pressures of our modern 24/7 society—including artificial light exposure, shift-work and jet-lag. In addition, circadian disruption is a common comorbidity in many different condition
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Robinson, Edward L., and Charles A. Fuller. "Endogenous thermoregulatory rhythms of squirrel monkeys in thermoneutrality and cold." American Journal of Physiology-Regulatory, Integrative and Comparative Physiology 276, no. 5 (1999): R1397—R1407. http://dx.doi.org/10.1152/ajpregu.1999.276.5.r1397.

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Whole body heat production (HP) and heat loss (HL) were examined to determine if the free-running circadian rhythm in body temperature (Tb) results from coordinated changes in HP and HL rhythms in thermoneutrality (27°C) as well as mild cold (17°C). Squirrel monkey metabolism ( n = 6) was monitored by both indirect and direct calorimetry, with telemetered measurement of Tb and activity. Feeding was also measured. Rhythms of HP, HL, and conductance were tightly coupled with the circadian Tb rhythm at both ambient temperatures (TA). At 17°C, increased HP compensated for higher HL at all phases o
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Lee, Jung Hyun, Eunsoo Moon, Jeonghyun Park, Chi Eun Oh, Yoo Rha Hong, and Min Yoon. "Optimization of Analysis of Circadian Rest-Activity Rhythm Using Cosinor Analysis in Mice." Psychiatry Investigation 19, no. 5 (2022): 380–85. http://dx.doi.org/10.30773/pi.2021.0395.

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Objective Data processing in analysis of circadian rhythm was performed in various ways. However, there was a lack of evidence for the optimal analysis of circadian rest-activity rhythm. Therefore, we aimed to perform mathematical simulations of data processing to investigate proper evidence for the optimal analysis of circadian rest-activity rhythm.Methods Locomotor activities of 20 ICR male mice were measured by infrared motion detectors. The data of locomotor activities was processed using data summation, data average, and data moving average methods for cosinor analysis. Circadian indices
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Filipski, Elisabeth, Verdun M. King, Marie-Christine Etienne, et al. "Persistent twenty-four hour changes in liver and bone marrow despite suprachiasmatic nuclei ablation in mice." American Journal of Physiology-Regulatory, Integrative and Comparative Physiology 287, no. 4 (2004): R844—R851. http://dx.doi.org/10.1152/ajpregu.00085.2004.

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Rest-activity or cortisol rhythms can be altered in cancer patients, a condition that may impair the benefits from a timed delivery of anticancer treatments. In rodents, the circadian pattern in rest-activity is suppressed by the destruction of the suprachiasmatic nuclei (SCN) in the hypothalamus. We sought whether such ablation would result in a similar alteration of cellular rhythms known to be relevant for anticancer drug chronopharmacology. The SCN of 77 B6D2F1 mice synchronized with 12 h of light and 12 h of darkness were destroyed by electrocoagulation [SCN(−)], while 34 animals were sha
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Li, Xiao, Ka Sin Caroline Shea, Ching Kwong Dino Wong, et al. "624 The association of circadian rhythms with cognitive functioning in children with attention-deficit hyperactivity disorder." Sleep 44, Supplement_2 (2021): A245. http://dx.doi.org/10.1093/sleep/zsab072.622.

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Abstract Introduction Disrupted circadian rhythms is associated with impaired cognitive function. Although circadian rhythm disturbances are commonly seen in individuals with attention-deficit hyperactivity disorder (ADHD), whether their cognitive functioning is thus affected remains unclear. This study aimed to examine the associations of circadian-related parameters with different cognitive abilities in children with ADHD. Methods Fifty-seven children with ADHD were recruited into this study (age range: 6–12 years, 66.7% male). They were assessed by parent-report questionnaires on sleep prob
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Yang, Hui-Wen, Sarah Chellappa, Arlen Gaba, Christian Cajochen, and Kun Hu. "758 Circadian rest-activity signatures in women with major depressive disorder." Sleep 44, Supplement_2 (2021): A295—A296. http://dx.doi.org/10.1093/sleep/zsab072.755.

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Abstract Introduction Patients with major depressive disorder (MDD) show disrupted circadian rhythms and sleep, including reduced daytime physical activity and poor sleep quality. However, previous findings are masked by psychotropic medication intake, co-morbid diseases and years of chronic mental illness. Here, we aim at identifying circadian motor activity patterns in unmedicated women at the onset of MDD. Methods Twelve young unmedicated women with MDD (Mean+-SD: 24.9+-5.2y; range: 18-33y) and eight age-matched healthy women (Mean+-SD: 24.5+-3.2y; range: 20-31y) participated in our study.
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McKinnon, Leela, David R. Samson, Charles L. Nunn, Amanda Rowlands, Katrina G. Salvante, and Pablo A. Nepomnaschy. "Technological infrastructure, sleep, and rest-activity patterns in a Kaqchikel Maya community." PLOS ONE 17, no. 11 (2022): e0277416. http://dx.doi.org/10.1371/journal.pone.0277416.

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Sleep duration, quality, and rest-activity pattern—a measure for inferring circadian rhythm—are influenced by multiple factors including access to electricity. Recent findings suggest that the safety and comfort afforded by technology may improve sleep but negatively impact rest-activity stability. According to the circadian entrainment hypothesis, increased access to electric lighting should lead to weaker and less uniform circadian rhythms, measured by stability of rest-activity patterns. Here, we investigate sleep in a Maya community in Guatemala who are in a transitional stage of industria
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Stahl, Sarah. "DIGITAL MONITORING OF SLEEP, MEALS, AND EXERCISE AS A PREVENTIVE INTERVENTION FOR DEPRESSION IN BEREAVED SPOUSES." Innovation in Aging 3, Supplement_1 (2019): S604. http://dx.doi.org/10.1093/geroni/igz038.2249.

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Abstract The death of a spouse brings profound change to bereaved survivors’ lifestyle and daily routine. These changes disrupt circadian rhythms which, in turn, places individuals at high risk for depression. The purpose of this study is to examine the feasibility and acceptability of a 12-week behavioral intervention that targets the timing and regularity of sleep, meals, and physical activity via digital monitoring and motivational health coaching. Participants were 60+ years of age and assessed on intervention acceptability and adherence, depression symptoms (Hamilton Rating Scale for Depr
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18

Fujioka, Haruna, Masato S. Abe, Taro Fuchikawa, Kazuki Tsuji, Masakazu Shimada, and Yasukazu Okada. "Ant circadian activity associated with brood care type." Biology Letters 13, no. 2 (2017): 20160743. http://dx.doi.org/10.1098/rsbl.2016.0743.

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In group-living animals, social interactions influence various traits including circadian activity. Maternal care, in particular, can have a strong effect on the circadian activity of parents or nurses across taxa. In social insects, nest-mates are known to have diverse activity rhythms; however, what kind of social environment is crucial in shaping an individual's rhythm is largely unknown. Here, we show that the focal brood types being taken care of (i.e. egg, larva and pupa) have significant effects on individual activity/rest rhythm, using the monomorphic ant Diacamma (putative species ind
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Sommer, Rosa, Lei Yu, Julie A. Schneider, David A. Bennett, Aron S. Buchman, and Andrew S. P. Lim. "Disrupted Rest-Activity Rhythms and Cerebral Small Vessel Disease Pathology in Older Adults." Stroke 52, no. 7 (2021): 2427–31. http://dx.doi.org/10.1161/strokeaha.120.030870.

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Background and Purpose: The pathogenesis of cerebral small vessel disease remains incompletely understood. The relationship between circadian rhythm disturbances and histopathologic measures of cerebral small vessel disease has not been studied. We hypothesized that disrupted circadian rest-activity rhythms would be associated with a higher burden of cerebral small vessel disease pathology. Methods: We studied 561 community-dwelling older adults (mean age at death, 91.2, 27.4% male) from the Rush Memory and Aging Project. We used actigraphy to quantify several measures of 24-hour rest-activity
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Erickson, Melissa, Terri Blackwell, Theresa Mau, et al. "CARDIORESPIRATORY FITNESS IS ASSOCIATED WITH CIRCADIAN BEHAVIORAL PARAMETERS OF PHYSICAL ACTIVITY IN OLDER ADULTS." Innovation in Aging 7, Supplement_1 (2023): 379. http://dx.doi.org/10.1093/geroni/igad104.1257.

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Abstract Cardiorespiratory fitness (VO2peak) declines with age, and this may be due in part to weakened circadian functions. Rhythmic patterns of rest-activity behavior over 24h represents a novel feature of physical activity, indicative of circadian behavior. Whether VO2peak relates to rest-activity rhythms (RAR) is unknown. We determined cross-sectional associations between VO2peak and RAR in SOMMA (N=714, Age: ≥70 yrs). Activity data from wrist-worn accelerometry (ActiGraph GT9X) were collected in one-minute epochs, over 8, 24h periods. An extension to the traditional cosine model was used
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Sultan, Armiya, Vivek Choudhary, and Arti Parganiha. "Characteristics of circadian rhythms in rest-activity and energy expendi-ture in cancer in-patients." South Asian Journal of Experimental Biology 4, no. 6 (2015): 327–35. http://dx.doi.org/10.38150/sajeb.4(6).p327-335.

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The objective of the current study was to assess the rest-activity (RA) and energy expenditure (EE) rhythms in cancer in-patients. Twenty chemothera-py receiving cancer in-patients (10 males and 10 females) and ten apparently healthy human subjects (5 males and 5 females) wore a non-invasive elec-tronic device – the Actical on their non dominant wrist. Data were recorded at 1-minute epoch for at least 3-4 consecutive days. Significant differences in RA and EE patterns were observed between cancer in-patients and control subjects, irrespective of gender. Control subjects showed absolute rhythm
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Silva, Eryck Holmes A., Nelyane Nayara M. Santana, Narita Renata M. Seixas, et al. "Blue light exposure-dependent improvement in robustness of circadian rest-activity rhythm in aged rats." PLOS ONE 18, no. 10 (2023): e0292342. http://dx.doi.org/10.1371/journal.pone.0292342.

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The aging effects on circadian rhythms have diverse implications including changes in the pattern of rhythmic expressions, such as a wide fragmentation of the rhythm of rest-activity and decrease in amplitude of activity regulated by the suprachiasmatic nucleus (SCN). The study of blue light on biological aspects has received great current interest due, among some aspects, to its positive effects on psychiatric disorders in humans. This study aims to evaluate the effect of blue light therapy on the SCN functional aspects, through the evaluation of the rest-activity rhythm, in aging rats. For t
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Bliwise, Donald L. "Circadian Rhythms and Agitation." International Psychogeriatrics 12, S1 (2000): 143–46. http://dx.doi.org/10.1017/s1041610200006931.

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In mammals, many aspects of physiology vary over the 24-hour day in a predictable, periodic manner. Hormones, such as thyroid-stimulating hormone and melatonin, as well as cardiovascular and autonomic measures such as heart rate, blood pressure, and body temperature all have a predictable diurnal pattern. It is important to understand that such variation is generated internally; that is, such variation represents a fundamental, endogenous circadian variation. Circadian variability is typically distinguished from the numerous exogenous factors that can influence the physiologic parameters in qu
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Gehrman, Phil, Matthew Marler, Jennifer L. Martin, Tamar Shochat, Jody Corey-Bloom, and Sonia Ancoli-Israel. "The relationship between dementia severity and rest/activity circadian rhythms." Neuropsychiatric Disease and Treatment 1, no. 2 (2005): 155–63. http://dx.doi.org/10.2147/nedt.1.2.155.61043.

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Leng, Y., T. Blackwell, P. M. Cawthon, S. Ancoli-Israel, K. Stone, and K. Yaffe. "1145 Longitudinal Association Between Circadian Activity Rhythms And Risk Of Incident Parkinson’s Disease In Older Men." Sleep 43, Supplement_1 (2020): A436. http://dx.doi.org/10.1093/sleep/zsaa056.1139.

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Abstract Introduction Disruption in circadian activity rhythms are very common in older adults, particularly among those with neurodegenerative diseases. However, the longitudinal association between circadian disruption and subsequent risk of developing neurodegenerative diseases, including Parkinson’s disease (PD), is unclear. Methods We examined rest-activity rhythms in 2930 community-dwelling older men (mean age 76.3 ± 5.5 years) without PD and followed them for incident PD over the next 11 years. 24-h rest-activity rhythm parameters (amplitude, mesor, robustness, acrophase) were generated
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Bulthuis, Nicholas, Katrina R. Spontak, Benjamin Kleeman, and Daniel J. Cavanaugh. "Neuronal Activity in Non-LNv Clock Cells Is Required to Produce Free-Running Rest:Activity Rhythms in Drosophila." Journal of Biological Rhythms 34, no. 3 (2019): 249–71. http://dx.doi.org/10.1177/0748730419841468.

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Circadian rhythms in behavior and physiology are produced by central brain clock neurons that can be divided into subpopulations based on molecular and functional characteristics. It has become clear that coherent behavioral rhythms result from the coordinated action of these clock neuron populations, but many questions remain regarding the organizational logic of the clock network. Here we used targeted genetic tools in Drosophila to eliminate either molecular clock function or neuronal activity in discrete clock neuron subsets. We find that neuronal firing is necessary across multiple clock
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Li, Xiao, Ka Sin Caroline Shea, Lok Fan Lau, et al. "625 The association between circadian rhythms and psychosocial functioning in children with attention deficit hyperactivity disorder." Sleep 44, Supplement_2 (2021): A245. http://dx.doi.org/10.1093/sleep/zsab072.623.

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Abstract Introduction Circadian rhythm disturbances, including delayed circadian rhythm and increased motor activity, are commonly seen in attention-deficit hyperactivity disorder (ADHD). Previous research suggested a link between circadian rhythm disturbances and poor psychosocial functioning in children, but such a relationship has not been examined in children with ADHD. This study aimed at examining the association between circadian-related parameters and psychosocial functioning in children with ADHD. Methods Seventy-nine children with ADHD were recruited into this study (age range: 6–12
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Dudek, Michal, and Qing-Jun Meng. "Running on time: the role of circadian clocks in the musculoskeletal system." Biochemical Journal 463, no. 1 (2014): 1–8. http://dx.doi.org/10.1042/bj20140700.

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The night and day cycle governs the circadian (24 hourly) rhythm of activity and rest in animals and humans. This is reflected in daily changes of the global gene expression pattern and metabolism, but also in the local physiology of various tissues. A central clock in the brain co-ordinates the rhythmic locomotion behaviour, as well as synchronizing various local oscillators, such as those found in the musculoskeletal system. It has become increasingly recognized that the internal molecular clocks in cells allow a tissue to anticipate the rhythmic changes in their local environment and the sp
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Brown, Laurence A., Sibah Hasan, Russell G. Foster, and Stuart N. Peirson. "COMPASS: Continuous Open Mouse Phenotyping of Activity and Sleep Status." Wellcome Open Research 1 (November 15, 2016): 2. http://dx.doi.org/10.12688/wellcomeopenres.9892.1.

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Background: Disruption of rhythms in activity and rest occur in many diseases, and provide an important indicator of healthy physiology and behaviour. However, outside the field of sleep and circadian rhythm research, these rhythmic processes are rarely measured due to the requirement for specialised resources and expertise. Until recently, the primary approach to measuring activity in laboratory rodents has been based on voluntary running wheel activity. By contrast, measuring sleep requires the use of electroencephalography (EEG), which involves invasive surgical procedures and time-consumin
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Brown, Laurence A., Sibah Hasan, Russell G. Foster, and Stuart N. Peirson. "COMPASS: Continuous Open Mouse Phenotyping of Activity and Sleep Status." Wellcome Open Research 1 (April 24, 2017): 2. http://dx.doi.org/10.12688/wellcomeopenres.9892.2.

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Background: Disruption of rhythms in activity and rest occur in many diseases, and provide an important indicator of healthy physiology and behaviour. However, outside the field of sleep and circadian rhythm research, these rhythmic processes are rarely measured due to the requirement for specialised resources and expertise. Until recently, the primary approach to measuring activity in laboratory rodents has been based on voluntary running wheel activity. By contrast, measuring sleep requires the use of electroencephalography (EEG), which involves invasive surgical procedures and time-consumin
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31

Hammad, Grégory, Mathilde Reyt, Nikita Beliy, et al. "pyActigraphy: Open-source python package for actigraphy data visualization and analysis." PLOS Computational Biology 17, no. 10 (2021): e1009514. http://dx.doi.org/10.1371/journal.pcbi.1009514.

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Over the past 40 years, actigraphy has been used to study rest-activity patterns in circadian rhythm and sleep research. Furthermore, considering its simplicity of use, there is a growing interest in the analysis of large population-based samples, using actigraphy. Here, we introduce pyActigraphy, a comprehensive toolbox for data visualization and analysis including multiple sleep detection algorithms and rest-activity rhythm variables. This open-source python package implements methods to read multiple data formats, quantify various properties of rest-activity rhythms, visualize sleep agendas
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Minaeva, O., E. Schat, E. Ceulemans, et al. "Individual-specific changes in circadian rest-activity rhythm and sleep in symptom-free patients tapering their antidepressant medication." European Psychiatry 65, S1 (2022): S679. http://dx.doi.org/10.1192/j.eurpsy.2022.1747.

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Introduction Group-level studies showed cross-sectional and prospective between-person associations between circadian rest-activity rhythms (RAR), physical activity (PA), sleep, and depressive symptoms. However, whether these associations replicate at the within-person level remains unclear. Therefore, it is clinically relevant to investigate these associations within persons and study whether changes in depressive symptoms are related to changes in circadian rhythm and sleep variables. Objectives To identify changes in circadian rhythm elements in proximity to a transition in depressive sympt
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Li, Xiao-Mei, Xu-Hui Liu, Elisabeth Filipski, et al. "Relationship of atypical melatonin rhythm with two circadian clock outputs in B6D2F1 mice." American Journal of Physiology-Regulatory, Integrative and Comparative Physiology 278, no. 4 (2000): R924—R930. http://dx.doi.org/10.1152/ajpregu.2000.278.4.r924.

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Circadian rhythms in body temperature, locomotor activity, and the circadian changes of plasma and pineal melatonin content were investigated in B6D2F1mice synchronized by 12 h of light and 12 h of darkness. During 8 wk continuous recording, activity and temperature displayed a marked stable and reproducible circadian rhythm, with both peaks occurring near the middle of darkness. Both 24- and 12-h rhythmic components were also significantly detected. Mean plasma melatonin concentration rose steadily during the light span and reached a maximum (30.6 ± 10.0 pg/ml) at 11 h after light onset (HALO
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Hoopes, Elissa, Michele D'Agata, Talia Brookstein-Burke, et al. "0003 On the Same Wavelength? Quantifying the Associations between Eating Timing and Rest-Activity Rhythms in Free-Living Adults." Sleep 45, Supplement_1 (2022): A1—A2. http://dx.doi.org/10.1093/sleep/zsac079.002.

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Abstract Introduction Misalignment between the central circadian clock and daily behaviors increases cardiometabolic morbidity and mortality risk, likely due to internal misalignment between central and peripheral circadian rhythms. Experimental studies suggest food intake may act as a time cue (‘zeitgeber’) for resetting circadian rhythms, representing a potential behavioral target to ameliorate circadian misalignment and associated health consequences. However, the extent to which eating timing relates to circadian rhythms in free-living adults is unclear. Therefore, we tested the associatio
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Fitzgerald, Emily S. "54 Sleep and Circadian Rhythms in Premanifest Huntington’s disease: Relationship with Cognition." Journal of the International Neuropsychological Society 29, s1 (2023): 565–66. http://dx.doi.org/10.1017/s1355617723007257.

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Objective:Huntington’s disease (HD) is a neurodegenerative disease characterised by motor, psychiatric and cognitive decline. Currently, no treatments have been identified in HD for slowing down cognitive decline or improving cognitive function. We are interested in identifying potentially modifiable factors in HD that can be targeted to improve or maintain cognitive function. Sleep and circadian disruption stand out as possible modifiable targets because sleep and circadian symptoms are common in HD, and such disruptions are known to impact cognition in the general population. Despite some em
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Perrier, Joy, Melvin Galin, Pierre Denise, Bénédicte Giffard, and Gaëlle Quarck. "Tackling Insomnia Symptoms through Vestibular Stimulation in Patients with Breast Cancer: A Perspective Paper." Cancers 15, no. 11 (2023): 2904. http://dx.doi.org/10.3390/cancers15112904.

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Insomnia symptoms are common among patients with breast cancer (BC; 20–70%) and are predictors of cancer progression and quality of life. Studies have highlighted sleep structure modifications, including increased awakenings and reduced sleep efficiency and total sleep time. Such modifications may result from circadian rhythm alterations consistently reported in this pathology and known as carcinogenic factors, including lower melatonin levels, a flattened diurnal cortisol pattern, and lower rest-activity rhythm amplitude and robustness. Cognitive behavioral therapy and physical activity are t
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Huang, Yong-Lu, Rong-Yu Liu, Qing-Song Wang, Eus J. W. Van Someren, Hao Xu, and Jiang-Ning Zhou. "Age-associated difference in circadian sleep–wake and rest–activity rhythms." Physiology & Behavior 76, no. 4-5 (2002): 597–603. http://dx.doi.org/10.1016/s0031-9384(02)00733-3.

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Pollak, C. P., P. E. Stokes, and P. R. Mourilhe. "Circadian rest-activity rhythms in demented nondemented elders and their caregivers." Biological Psychiatry 39, no. 7 (1996): 661. http://dx.doi.org/10.1016/0006-3223(96)84486-6.

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Rogers, Tara S., Stephanie Harrison, Christine Swanson, et al. "Rest-activity circadian rhythms and bone mineral density in elderly men." Bone Reports 7 (December 2017): 156–63. http://dx.doi.org/10.1016/j.bonr.2017.11.001.

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Wu, JQ, K. Hu, K. Stavitsky Gilbert, and A. Cronin-Golomb. "1142 CIRCADIAN REST-ACTIVITY RHYTHMS AND COGNITIVE FUNCTION IN PARKINSON’S DISEASE." Sleep 40, suppl_1 (2017): A426. http://dx.doi.org/10.1093/sleepj/zsx050.1141.

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Wang, Joshua L., Andrew S. Lim, Wei-Yin Chiang, et al. "Suprachiasmatic neuron numbers and rest-activity circadian rhythms in older humans." Annals of Neurology 78, no. 2 (2015): 317–22. http://dx.doi.org/10.1002/ana.24432.

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42

Chaix, Amandine, Emily N. C. Manoogian, Girish C. Melkani, and Satchidananda Panda. "Time-Restricted Eating to Prevent and Manage Chronic Metabolic Diseases." Annual Review of Nutrition 39, no. 1 (2019): 291–315. http://dx.doi.org/10.1146/annurev-nutr-082018-124320.

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Molecular clocks are present in almost every cell to anticipate daily recurring and predictable changes, such as rhythmic nutrient availability, and to adapt cellular functions accordingly. At the same time, nutrient-sensing pathways can respond to acute nutrient imbalance and modulate and orient metabolism so cells can adapt optimally to a declining or increasing availability of nutrients. Organismal circadian rhythms are coordinated by behavioral rhythms such as activity–rest and feeding–fasting cycles to temporally orchestrate a sequence of physiological processes to optimize metabolism. Ba
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Yue, Yiwei, Jill Rabinowitz, Yang An, et al. "ASSOCIATIONS OF CIRCADIAN REST/ACTIVITY RHYTHMS WITH METABOLIC SYNDROME IN MIDDLE-AGED AND OLDER ADULTS." Innovation in Aging 8, Supplement_1 (2024): 81. https://doi.org/10.1093/geroni/igae098.0252.

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Abstract Circadian rhythm disturbances often co-occur with adverse cardiometabolic outcomes, including high blood pressure, obesity, and diabetes. However, the links between disrupted circadian rhythms and metabolic syndrome (MetS) are understudied in later life. This study examined associations between actigraphic circadian rest/activity rhythm (CRAR) metrics and MetS in 388 Baltimore Longitudinal Study of Aging participants who completed 6.6±1.0 nights of wrist actigraphy (Mean age=72.6±10.1, 20.6% Black adults, 54.1% women) and measures of MetS. Predictors were relative amplitude (RA), inte
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Yevtushenko, Iryna, Olena Butok, Olena Otroshko, and Andriy Storozhenko. "Accounting for an individual approach to training of athletes in playing sports (on the example of basketball, volleyball and futsal)." Human and nation's health 1, no. 1 (2023): 21–36. http://dx.doi.org/10.31548/humanhealth.1.2023.21.

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The article is devoted to the study of ways to optimize the training process for student basketball, volleyball and futsal teams, taking into account the individual biorhythmic properties of female athletes. The study determines the importance of individualizing training and preparation, in particular, taking into account circadian rhythms and other biorhythmic aspects that determine physiological and psychological changes in female athletes during the day. The tasks of the study included testing the biological rhythms of female athletes to improve the training process. 36 sportswomen (14 bask
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Tsai, Shao-Yu, Kathryn E. Barnard, Martha J. Lentz, and Karen A. Thomas. "Mother-Infant Activity Synchrony as a Correlate of the Emergence of Circadian Rhythm." Biological Research For Nursing 13, no. 1 (2010): 80–88. http://dx.doi.org/10.1177/1099800410378889.

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Objective: Entrainment to the day—night cycle is critical for infant sleep and social development. Synchronization of infant circadian systems with the social 24-hr day may require maternal activity signals as an entraining cue. This descriptive and exploratory research examines the activity level and circadian pattern in mothers and infants. Method: Twenty-two healthy mothers and their infants (postnatal age 49.8 ± 17.1 days) wore actigraph monitors for seven days. Daytime (06:00—21:59) and nighttime (22:00—05:59) activity levels and circadian parameters of rest—activity patterns (i.e., mesor
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Lukas, Molly, Margaret Doyle, Taylor Intihar, et al. "0841 Feasibility of Actigraphy during a Daytime Bright Pilot Study in the Medical ICU." SLEEP 46, Supplement_1 (2023): A370—A371. http://dx.doi.org/10.1093/sleep/zsad077.0841.

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Abstract Introduction Medical intensive care unit (MICU) light patterns are inadequate for proper circadian alignment. Sleep disruption and circadian misalignment are observed in MICU patients and adversely impact patient outcomes. We sought to establish the feasibility of using longitudinal actigraphy to measure diurnal rest-activity patterns, as a in the context of a pilot study evaluating daytime bright light (DBL). In an exploratory manner, we analyzed diurnal rest-activity characteristics. Methods Patients >50 years admitted to the MICU without pre-existing circadian disruption wer
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Akaarir, Mourad, José Manuel Pujol, Margalida Suau, et al. "Activity–Rest Circadian Rhythm of the Pearly Razorfish in Its Natural Habitat, before and during Its Mating." Biology 12, no. 6 (2023): 810. http://dx.doi.org/10.3390/biology12060810.

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Recent technological advances in marine biotelemetry have demonstrated that marine fish species perform activity–rest rhythms that have relevant ecological and evolutionary consequences. The main objective of the present report is to study the circadian rhythm of activity–rest of the pearly razorfish, Xyrichtys novacula in its own habitat, before and during the reproduction season using a novel biotelemetry system. This fish species is a small-bodied marine species that inhabits most shallow soft habitats of temperate areas and has a high interest for commercial and recreational fisheries. The
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Pfaeffle, Claire, Kristine Wilkens, Zhiwei Zhao, et al. "0681 Circadian Rest/activity Rhythms Are Associated with Cognitive Flexibility Among Older Adults with Insomnia." SLEEP 47, Supplement_1 (2024): A291. http://dx.doi.org/10.1093/sleep/zsae067.0681.

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Abstract Introduction Circadian rest/activity rhythms (RARs) are associated with cognitive function among older adults. Reports of poor cognitive function are common among individuals with insomnia. We examined the association of circadian RARs with performance in multiple cognitive domains among older adults with insomnia. Methods Older adults with insomnia were recruited from a tertiary academic medical center. Participants wore an actigraph and completed concurrent sleep diaries for up to 14 days. We derived nonparametric circadian RARs including relative amplitude (RA), interdaily stabilit
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Helfrich-Förster, Charlotte, Michael N. Nitabach, and Todd C. Holmes. "Insect circadian clock outputs." Essays in Biochemistry 49 (June 30, 2011): 87–101. http://dx.doi.org/10.1042/bse0490087.

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Insects display an impressive variety of daily rhythms, which are most evident in their behaviour. Circadian timekeeping systems that generate these daily rhythms of physiology and behaviour all involve three interacting elements: the timekeeper itself (i.e. the clock), inputs to the clock through which it entrains and otherwise responds to environmental cues such as light and temperature, and outputs from the clock through which it imposes daily rhythms on various physiological and behavioural parameters. In insects, as in other animals, cellular clocks are embodied in clock neurons capable o
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Alfini, Alfonso, Marilyn Albert, Andreia Faria, et al. "045 Associations of Actigraphic Sleep and Circadian Rest/Activity Rhythms with Cognition in the Early Phase of Alzheimer’s Disease." Sleep 44, Supplement_2 (2021): A19—A20. http://dx.doi.org/10.1093/sleep/zsab072.044.

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Abstract Introduction Alterations in sleep and circadian rhythms are common in persons with Alzheimer’s disease (AD) dementia, but the nature of such changes in the early phases of AD remains unclear. This study compared sleep and circadian rest/activity rhythms (RARs), measured by standard and novel actigraphic indices, between participants with normal cognition or mild cognitive impairment (MCI), and examined cross-sectional associations between these measures and cognition. Methods Actigraphy data were collected in 179 individuals (mean age=72.6 years, gender=64.8% female) with normal cogni
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