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Articles de revues sur le sujet « Rest-activity circadian rhythm »

Auteur : Grafiati

Publié le 9 mars 2023

Mis à jour le 31 juillet 2025

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1

Calogiuri, Giovanna, Andi Weydahl, and Franca Carandente. "Methodological Issues for Studying the Rest–Activity Cycle and Sleep Disturbances." Biological Research For Nursing 15, no. 1 (2011): 5–12. http://dx.doi.org/10.1177/1099800411416224.

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Shift work schedules, intensive physical exercise late in the day, psychological stress, or a busy lifestyle might induce disorders of the circadian structure, which can affect health on both the physiological and neurobehavioral levels. Rest–activity rhythm is strongly connected with an organism’s circadian structure, and irregular sleep–wake patterns can lead to a disruption of entrainment, resulting in physiological and neurobehavioral dysfunction. Shift nurses are often subject to disturbances in the quality and duration of their sleep, raising the possibility of negative impacts on their

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Yeung, Chris Ho Ching, Cici Bauer, and Qian Xiao. "Associations between Rest–Activity Rhythms and Liver Function Tests: The US National Health and Nutrition Examination Survey, 2011–2014." Clocks & Sleep 5, no. 4 (2023): 667–85. http://dx.doi.org/10.3390/clockssleep5040045.

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Liver functions are regulated by the circadian rhythm; however, whether a weakened circadian rhythm is associated with impaired liver function is unclear. This study aims to investigate the association of characteristics of rest–activity rhythms with abnormal levels of biomarkers of liver function. Data were obtained from the National Health and Nutrition Examination Survey 2011–2014. Seven rest–activity rhythm parameters were derived from 24 h actigraphy data using the extended cosine model and non-parametric methods. Multiple logistic regression and multiple linear regression models were use

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Arzola-Rodríguez, Jesús José. "Sueño y ritmos circadianos en supervivientes de falla respiratoria aguda." Kompass Neumología 3, no. 1 (2021): 14–15. http://dx.doi.org/10.1159/000513799.

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<b>Background:</b> Little is known about sleep and circadian rhythms in survivors of acute respiratory failure (ARF) after hospital discharge. <b>Objectives:</b> To examine sleep and rest-activity circadian rhythms in ARF survivors 3 months after hospital discharge, and to compare them with a community-dwelling population. <b>Methods:</b> Sleep diary, actigraphy data, and insomnia symptoms were collected in a pilot study of 14 ARF survivors. Rest-activity circadian rhythms were assessed with wrist actigraphy and sleep diary for 9 days, and were analyzed by c

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Gander, P. H., R. Lydic, H. E. Albers, and M. C. Moore-Ede. "Forced internal desynchronization between circadian temperature and activity rhythms in squirrel monkeys." American Journal of Physiology-Regulatory, Integrative and Comparative Physiology 248, no. 5 (1985): R567—R572. http://dx.doi.org/10.1152/ajpregu.1985.248.5.r567.

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In an attempt to force internal desynchronization between the rest-activity rhythm and the body temperature rhythm of the squirrel monkey (Saimiri sciureus), five animals were studied in a 14:14 light-dark cycle. In four animals a 28-h spectral component was found to predominate in the rest-activity rhythm, whereas an unentrained circadian component (tau = 25.9 +/- 0.4 h) predominated in the body temperature rhythm. Plots of the cycle-by-cycle acrophases of the two rhythms confirm that they desynchronize, due to the failure of the temperature rhythm to entrain to the light-dark cycle. These da

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Slyepchenko, Anastasiya, Olivia R. Allega, Xiamin Leng, et al. "Association of functioning and quality of life with objective and subjective measures of sleep and biological rhythms in major depressive and bipolar disorder." Australian & New Zealand Journal of Psychiatry 53, no. 7 (2019): 683–96. http://dx.doi.org/10.1177/0004867419829228.

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Objective: Disruptions in biological rhythms and sleep are a core aspect of mood disorders, with sleep and rhythm changes frequently occurring prior to and during mood episodes. Wrist-worn actigraphs are increasingly utilized to measure ambulatory activity rhythm and sleep patterns. Methods: A comprehensive study using subjective and objective measures of sleep and biological rhythms was conducted in 111 participants (40 healthy volunteers [HC], 38 with major depressive disorder [MDD] and 33 with bipolar disorder [BD]). Participants completed 15-day actigraphy and first-morning urine samples t

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Kim, Minjee, Kathryn Reid, Matthew Maas, et al. "164 Greater Light Exposure Is Associated with More Robust Rest-Activity Rhythms in Community-Dwelling Older Adults." Sleep 44, Supplement_2 (2021): A67. http://dx.doi.org/10.1093/sleep/zsab072.163.

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Abstract Introduction Disrupted circadian rest-activity rhythms in older adults have been associated with an increased risk of cognitive decline and mortality. While light is one of the most potent synchronizing agents for the human circadian system, little is known about how light may influence rest-activity rhythms in older adults. We aimed to investigate the relationship between the amount of light exposure and rest-activity rhythm parameters using actigraphy data from a large cohort study. Methods 553 community-dwelling older adults (aged 72±5, 142 (25.5%) female) from the Chicago Healthy

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Fujioka, Haruna, Masato S. Abe, Taro Fuchikawa, Kazuki Tsuji, Masakazu Shimada, and Yasukazu Okada. "Ant circadian activity associated with brood care type." Biology Letters 13, no. 2 (2017): 20160743. http://dx.doi.org/10.1098/rsbl.2016.0743.

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In group-living animals, social interactions influence various traits including circadian activity. Maternal care, in particular, can have a strong effect on the circadian activity of parents or nurses across taxa. In social insects, nest-mates are known to have diverse activity rhythms; however, what kind of social environment is crucial in shaping an individual's rhythm is largely unknown. Here, we show that the focal brood types being taken care of (i.e. egg, larva and pupa) have significant effects on individual activity/rest rhythm, using the monomorphic ant Diacamma (putative species ind

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Dispersyn, Garance, Laure Pain, and Yvan Touitou. "Circadian Disruption of Body Core Temperature and Rest–Activity Rhythms after General (Propofol) Anesthesia in Rats." Anesthesiology 110, no. 6 (2009): 1305–15. http://dx.doi.org/10.1097/aln.0b013e3181a10225.

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Background General anesthesia is commonly associated with sleep disorders, fatigue, drowsiness, and mood alterations in patients. The authors examined whether general (propofol) anesthesia can impact the circadian temporal structure by disturbing circadian rest-activity and body temperature rhythms under normal light-dark conditions (light-dark 12:12 h) in rats. Methods A group of rats was anesthetized with propofol, and another was injected with 10% Intralipid, which was used as a control lipidic solution. The authors examined six groups of rats according to the Zeitgeber time of intraperiton

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Giannetto, C., F. Fazio, A. Assenza, G. Caola, P. Pennisi, and G. Piccione. "Circadian rhythms of redox states and total locomotor activity in dairy cattle." Czech Journal of Animal Science 55, No. 5 (2010): 183–89. http://dx.doi.org/10.17221/306/2009-cjas.

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We want to study the circadian rhythm of dROMs and anti-oxidative power in dairy cattle during dry period and the possible involvement of the circadian organization of rest/activity cycles in the fluctuation of redox state. For this purpose we recorded TLA in five clinically healthy Bruna Italian dairy cattle by means of an actigraphy-based data logger, Actiwatch-Mini<sup>&reg;</sup>. Blood samples were collected every 3 hours over a 48-hour period for the assessment of free radicals (dROMs) and the antioxidant power: antioxidant barrier (Oxy-ads) and thiol-antioxidant barrier

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Lee, Jung Hyun, Eunsoo Moon, Jeonghyun Park, Chi Eun Oh, Yoo Rha Hong, and Min Yoon. "Optimization of Analysis of Circadian Rest-Activity Rhythm Using Cosinor Analysis in Mice." Psychiatry Investigation 19, no. 5 (2022): 380–85. http://dx.doi.org/10.30773/pi.2021.0395.

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Objective Data processing in analysis of circadian rhythm was performed in various ways. However, there was a lack of evidence for the optimal analysis of circadian rest-activity rhythm. Therefore, we aimed to perform mathematical simulations of data processing to investigate proper evidence for the optimal analysis of circadian rest-activity rhythm.Methods Locomotor activities of 20 ICR male mice were measured by infrared motion detectors. The data of locomotor activities was processed using data summation, data average, and data moving average methods for cosinor analysis. Circadian indices

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Calogiuri, Giovanna, Andi Weydahl, and Eliana Roveda. "Effects of Sleep Loss and Strenuous Physical Activity on the Rest–Activity Circadian Rhythm." Biological Research For Nursing 13, no. 4 (2010): 409–18. http://dx.doi.org/10.1177/1099800410392021.

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Objective. Rest–activity circadian rhythm is strongly linked to an organism’s entrainment. Sleep loss and prolonged fatigue could affect the circadian system, inducing neurobehavioral deficits. The Finnmarksløpet is Europe’s longest dogsled race. In this competition, lasting up to 7 days, participants (mushers) are physically active most of the time, having little and fragmented rest. Therefore, the race provides an opportunity to investigate the effects of prolonged fatigue and sleep loss. Methods. Ten mushers, participating in the 500 km and 1,000 km categories, underwent continuous actigrap

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Fujioka, Haruna, Masato S. Abe, and Yasukazu Okada. "Individual Ants Do Not Show Activity-Rest Rhythms in Nest Conditions." Journal of Biological Rhythms 36, no. 3 (2021): 297–310. http://dx.doi.org/10.1177/07487304211002934.

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Circadian rhythms, which respond to the day-night cycle on the earth, arise from the endogenous timekeeping system within organisms, called the “biological clock.” For accurate circadian rhythms, daily fluctuations in light and temperature are considered one of the important time cues. In social insects, both abiotic and biotic factors (i.e., social interactions) play a significant role in activity-rest rhythm regulation. However, it is challenging to monitor individual activity-rest rhythms in a colony because of the large group size and small body size. Therefore, it is unclear whether indiv

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van Someren, Eus J. W., Eveline E. O. Hagebeuk, Cees Lijzenga, et al. "Circadian rest—activity rhythm disturbances in alzheimer's disease." Biological Psychiatry 40, no. 4 (1996): 259–70. http://dx.doi.org/10.1016/0006-3223(95)00370-3.

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Domínguez-Valdés, Teresa, Cristina Bonnin-Arias, Cristina Alvarez-Peregrina, et al. "Violet Light Effects on the Circadian Rest–Activity Rhythm and the Visual System." Clocks & Sleep 6, no. 3 (2024): 433–45. http://dx.doi.org/10.3390/clockssleep6030029.

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Background: Rooms illuminated by “black light” (<400 nm wavelength) has become popular, but there is not enough scientific evidence to support its implementation. This study aims to assess the effects of violet light (392 nm) on the circadian rest–activity rhythm and the visual system through animal experimentation. Materials and results: Five groups of four mice were exposed to different white light, violet light, and dark periods, and their circadian rhythm was analyzed by measuring the circadian period using rest–activity cycles. Electroretinographic recordings and structural analysis of

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Minaeva, O., E. Schat, E. Ceulemans, et al. "Individual-specific changes in circadian rest-activity rhythm and sleep in symptom-free patients tapering their antidepressant medication." European Psychiatry 65, S1 (2022): S679. http://dx.doi.org/10.1192/j.eurpsy.2022.1747.

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Introduction Group-level studies showed cross-sectional and prospective between-person associations between circadian rest-activity rhythms (RAR), physical activity (PA), sleep, and depressive symptoms. However, whether these associations replicate at the within-person level remains unclear. Therefore, it is clinically relevant to investigate these associations within persons and study whether changes in depressive symptoms are related to changes in circadian rhythm and sleep variables. Objectives To identify changes in circadian rhythm elements in proximity to a transition in depressive sympt

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McKinnon, Leela, David R. Samson, Charles L. Nunn, Amanda Rowlands, Katrina G. Salvante, and Pablo A. Nepomnaschy. "Technological infrastructure, sleep, and rest-activity patterns in a Kaqchikel Maya community." PLOS ONE 17, no. 11 (2022): e0277416. http://dx.doi.org/10.1371/journal.pone.0277416.

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Sleep duration, quality, and rest-activity pattern—a measure for inferring circadian rhythm—are influenced by multiple factors including access to electricity. Recent findings suggest that the safety and comfort afforded by technology may improve sleep but negatively impact rest-activity stability. According to the circadian entrainment hypothesis, increased access to electric lighting should lead to weaker and less uniform circadian rhythms, measured by stability of rest-activity patterns. Here, we investigate sleep in a Maya community in Guatemala who are in a transitional stage of industria

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Jean-Louis, Girardin, Ferdinand Zizi, Hans Von Gizycki, and Harvey Taub. "Effects of Melatonin in Two Individuals with Alzheimer's Disease." Perceptual and Motor Skills 87, no. 1 (1998): 331–39. http://dx.doi.org/10.2466/pms.1998.87.1.331.

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Dementia has been associated with circadian rhythm disturbances expressed in several dimensions including body temperature, hormonal concentrations, sleep and wakefulness patterns, and rest-activity cycles. These disturbances may be the result of a dampening in the amplitude of the circadian rhythm. One of the symptoms associated with the aging process has been a decline in the amplitude of the melatonin rhythm. Here, the results of melatonin administration to two patients with Alzheimer's disease are presented. Melatonin administration enhanced and stabilized the circadian rest-activity rhyth

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Yesavage, Jerome A., Leah Friedman, Helena C. Kraemer, et al. "A Follow-Up Study of Actigraphic Measures in Home-Residing Alzheimer's Disease Patients." Journal of Geriatric Psychiatry and Neurology 11, no. 1 (1998): 7–10. http://dx.doi.org/10.1177/089198879801100103.

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This article reports cross-sectional and follow-up data with actigraphic measures of nocturnal sleep and rest/activity in 61 Alzheimer's disease (AD) patients as well as the relation of actigraphic measures to levels of behavioral disturbance across different stages of the disease. Over the course of approximately 1.5 years' follow-up, patients showed significant deterioration of nocturnal sleep parameters, but no significant change in rest/activity circadian rhythm parameters. There were also significant correlations among nocturnal sleep, rest/activity circadian rhythm, and behavioral distur

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Nishihara, Kyoko, Shigeko Horiuchi, Hiromi Eto, and Sunao Uchida. "The development of infants' circadian rest–activity rhythm and mothers' rhythm." Physiology & Behavior 77, no. 1 (2002): 91–98. http://dx.doi.org/10.1016/s0031-9384(02)00846-6.

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Robinson, Edward L., and Charles A. Fuller. "Endogenous thermoregulatory rhythms of squirrel monkeys in thermoneutrality and cold." American Journal of Physiology-Regulatory, Integrative and Comparative Physiology 276, no. 5 (1999): R1397—R1407. http://dx.doi.org/10.1152/ajpregu.1999.276.5.r1397.

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Whole body heat production (HP) and heat loss (HL) were examined to determine if the free-running circadian rhythm in body temperature (Tb) results from coordinated changes in HP and HL rhythms in thermoneutrality (27°C) as well as mild cold (17°C). Squirrel monkey metabolism ( n = 6) was monitored by both indirect and direct calorimetry, with telemetered measurement of Tb and activity. Feeding was also measured. Rhythms of HP, HL, and conductance were tightly coupled with the circadian Tb rhythm at both ambient temperatures (TA). At 17°C, increased HP compensated for higher HL at all phases o

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Roh, Hyun Woong, and Sang Joon Son. "Rest-Activity Pattern and Circadian Phase Alterations Across the Alzheimer’s Disease Clinical Spectrum." Chronobiology in Medicine 3, no. 4 (2021): 137–41. http://dx.doi.org/10.33069/cim.2021.0029.

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Actigraphy-derived locomotor activity recordings are novel and critical tools for evaluating rest-activity pattern and circadian phase in humans. We conducted a narrative review assessing rest-activity pattern and circadian phase alterations within various stages of Alzheimer’s disease, in consideration of the reciprocal associations between neurodegeneration and circadian rhythm disruption in patients with Alzheimer’s disease. The goal of this review was to characterize possible associations between circadian rhythm disruption and neurodegeneration in Alzheimer’s disease. To the best of our k

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Chin, Wei-Chih, Pao-Hsien Chu, Lung-Sheng Wu, et al. "The Prognostic Significance of Sleep and Circadian Rhythm for Myocardial Infarction Outcomes: Case-Control Study." Journal of Medical Internet Research 27 (February 4, 2025): e63897. https://doi.org/10.2196/63897.

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Background Myocardial infarction (MI) is a medical emergency resulting from coronary artery occlusion. Patients with acute MI often experience disturbed sleep and circadian rhythm. Most previous studies assessed the premorbid sleep and circadian rhythm of patients with MI and their correlations with cardiovascular disease. However, little is known about post-MI sleep and circadian rhythm and their impacts on prognosis. The use of actigraphy with different algorithms to evaluate sleep and circadian rhythm after acute MI has the potential for predicting outcomes and preventing future disease pro

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Erickson, Melissa, Terri Blackwell, Theresa Mau, et al. "CARDIORESPIRATORY FITNESS IS ASSOCIATED WITH CIRCADIAN BEHAVIORAL PARAMETERS OF PHYSICAL ACTIVITY IN OLDER ADULTS." Innovation in Aging 7, Supplement_1 (2023): 379. http://dx.doi.org/10.1093/geroni/igad104.1257.

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Abstract Cardiorespiratory fitness (VO2peak) declines with age, and this may be due in part to weakened circadian functions. Rhythmic patterns of rest-activity behavior over 24h represents a novel feature of physical activity, indicative of circadian behavior. Whether VO2peak relates to rest-activity rhythms (RAR) is unknown. We determined cross-sectional associations between VO2peak and RAR in SOMMA (N=714, Age: ≥70 yrs). Activity data from wrist-worn accelerometry (ActiGraph GT9X) were collected in one-minute epochs, over 8, 24h periods. An extension to the traditional cosine model was used

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Akaarir, Mourad, José Manuel Pujol, Margalida Suau, et al. "Activity–Rest Circadian Rhythm of the Pearly Razorfish in Its Natural Habitat, before and during Its Mating." Biology 12, no. 6 (2023): 810. http://dx.doi.org/10.3390/biology12060810.

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Recent technological advances in marine biotelemetry have demonstrated that marine fish species perform activity–rest rhythms that have relevant ecological and evolutionary consequences. The main objective of the present report is to study the circadian rhythm of activity–rest of the pearly razorfish, Xyrichtys novacula in its own habitat, before and during the reproduction season using a novel biotelemetry system. This fish species is a small-bodied marine species that inhabits most shallow soft habitats of temperate areas and has a high interest for commercial and recreational fisheries. The

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Henríquez-Beltrán, Mario, Iván Benítez, Thalía Belmonte, et al. "Association between Acute Respiratory Distress Syndrome Due to COVID-19 and Long-Term Sleep and Circadian Sleep–Wake Disorders." Journal of Clinical Medicine 12, no. 20 (2023): 6639. http://dx.doi.org/10.3390/jcm12206639.

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Current studies agree on the impact of sleep and circadian rest–activity rhythm alterations in acute respiratory distress syndrome (ARDS) survivors. However, research on the duration of this impact is scarce. In this study, we evaluate the impact of ARDS on the sleep and circadian rest–activity rhythm of COVID-19 survivors twelve months after hospital discharge. This is a prospective study including COVID-19 survivors with and without ARDS during hospitalization. Data was collected four and twelve months after hospital discharge. The interventions included one-week wrist actigraphy and a home

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Silva, Eryck Holmes A., Nelyane Nayara M. Santana, Narita Renata M. Seixas, et al. "Blue light exposure-dependent improvement in robustness of circadian rest-activity rhythm in aged rats." PLOS ONE 18, no. 10 (2023): e0292342. http://dx.doi.org/10.1371/journal.pone.0292342.

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The aging effects on circadian rhythms have diverse implications including changes in the pattern of rhythmic expressions, such as a wide fragmentation of the rhythm of rest-activity and decrease in amplitude of activity regulated by the suprachiasmatic nucleus (SCN). The study of blue light on biological aspects has received great current interest due, among some aspects, to its positive effects on psychiatric disorders in humans. This study aims to evaluate the effect of blue light therapy on the SCN functional aspects, through the evaluation of the rest-activity rhythm, in aging rats. For t

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Nunes, Deuzilane Muniz, Bruno S. B. Gonçalves, Carina Aparecida Tardelli Peixoto, Veralice Meireles Sales De Bruin, Fernando Mazzilli Louzada, and Pedro Felipe Carvalhedo De Bruin. "Circadian rest-activity rhythm in chronic obstructive pulmonary disease." Chronobiology International 34, no. 9 (2017): 1315–19. http://dx.doi.org/10.1080/07420528.2017.1352594.

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Filardi, Marco, Fabio Pizza, Oliviero Bruni, Vincenzo Natale, and Giuseppe Plazzi. "Circadian Rest-Activity Rhythm in Pediatric Type 1 Narcolepsy." Sleep 39, no. 6 (2016): 1241–47. http://dx.doi.org/10.5665/sleep.5842.

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Zhang, Rui, Peter Manza, Dardo Tomasi, et al. "0693 Rest-activity rhythm in Methadone and Buprenorphine-maintained patients." SLEEP 46, Supplement_1 (2023): A304—A305. http://dx.doi.org/10.1093/sleep/zsad077.0693.

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Abstract Introduction Opioid use disorder (OUD) is a chronic relapsing disorder with a high overdose death rate. In OUD, sleep and circadian disruptions are highly prevalent, interfere with retention in opioid maintenance treatment (OMT) and increase relapse. Growing evidence suggests a link between sleep/circadian disruptions and dopaminergic (DA) signaling which accounts for addictive properties of drugs of abuse. The current study investigated rest-activity rhythm in Methadone and Buprenorphine-maintained patients and how it relates to DA changes in patients. Methods To access rest-activity

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Li, Xiao, Ka Sin Caroline Shea, Lok Fan Lau, et al. "625 The association between circadian rhythms and psychosocial functioning in children with attention deficit hyperactivity disorder." Sleep 44, Supplement_2 (2021): A245. http://dx.doi.org/10.1093/sleep/zsab072.623.

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Abstract Introduction Circadian rhythm disturbances, including delayed circadian rhythm and increased motor activity, are commonly seen in attention-deficit hyperactivity disorder (ADHD). Previous research suggested a link between circadian rhythm disturbances and poor psychosocial functioning in children, but such a relationship has not been examined in children with ADHD. This study aimed at examining the association between circadian-related parameters and psychosocial functioning in children with ADHD. Methods Seventy-nine children with ADHD were recruited into this study (age range: 6–12

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Gao, Qian, Juan Sheng, Song Qin, and Luoying Zhang. "Chronotypes and affective disorders: A clock for mood?" Brain Science Advances 5, no. 3 (2019): 145–60. http://dx.doi.org/10.26599/bsa.2019.9050018.

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Affective disorders are often accompanied by circadian rhythm disruption and the major symptoms of mental illness occur in a rhythmic manner. Chronotype, also known as circadian preference for rest or activity, is believed to exert a substantial influence on mental health. Here, we review the connection between chronotypes and affective disorders, and discuss the potential underlying mechanisms between these two phenomena.

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Hammad, Grégory, Mathilde Reyt, Nikita Beliy, et al. "pyActigraphy: Open-source python package for actigraphy data visualization and analysis." PLOS Computational Biology 17, no. 10 (2021): e1009514. http://dx.doi.org/10.1371/journal.pcbi.1009514.

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Over the past 40 years, actigraphy has been used to study rest-activity patterns in circadian rhythm and sleep research. Furthermore, considering its simplicity of use, there is a growing interest in the analysis of large population-based samples, using actigraphy. Here, we introduce pyActigraphy, a comprehensive toolbox for data visualization and analysis including multiple sleep detection algorithms and rest-activity rhythm variables. This open-source python package implements methods to read multiple data formats, quantify various properties of rest-activity rhythms, visualize sleep agendas

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Xu, Yanyan, Shaoyong Su, William V. McCall, Carlos Isales, Harold Snieder, and Xiaoling Wang. "Rest-activity circadian rhythm and impaired glucose tolerance in adults: an analysis of NHANES 2011–2014." BMJ Open Diabetes Research & Care 10, no. 2 (2022): e002632. http://dx.doi.org/10.1136/bmjdrc-2021-002632.

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IntroductionCircadian rhythm disturbance occurs in type 2 diabetes, yet it is unknown whether it also exists in the prediagnostic phase of the disease. Thus, we examined the association of rest-activity circadian rhythm with 2-hour glucose levels and the risk of impaired glucose tolerance (IGT) in a nationally representative sample of adults without diabetes using a cross-sectional design.Research design and methodsWe analyzed data from 2760 adults without diabetes (age ≥20) with at least 4 days of validated accelerometer recordings and a valid oral glucose tolerance test from the National Hea

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Li, Xiao-Mei, Xu-Hui Liu, Elisabeth Filipski, et al. "Relationship of atypical melatonin rhythm with two circadian clock outputs in B6D2F1 mice." American Journal of Physiology-Regulatory, Integrative and Comparative Physiology 278, no. 4 (2000): R924—R930. http://dx.doi.org/10.1152/ajpregu.2000.278.4.r924.

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Circadian rhythms in body temperature, locomotor activity, and the circadian changes of plasma and pineal melatonin content were investigated in B6D2F1mice synchronized by 12 h of light and 12 h of darkness. During 8 wk continuous recording, activity and temperature displayed a marked stable and reproducible circadian rhythm, with both peaks occurring near the middle of darkness. Both 24- and 12-h rhythmic components were also significantly detected. Mean plasma melatonin concentration rose steadily during the light span and reached a maximum (30.6 ± 10.0 pg/ml) at 11 h after light onset (HALO

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Stahl, Sarah. "DIGITAL MONITORING OF SLEEP, MEALS, AND EXERCISE AS A PREVENTIVE INTERVENTION FOR DEPRESSION IN BEREAVED SPOUSES." Innovation in Aging 3, Supplement_1 (2019): S604. http://dx.doi.org/10.1093/geroni/igz038.2249.

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Abstract The death of a spouse brings profound change to bereaved survivors’ lifestyle and daily routine. These changes disrupt circadian rhythms which, in turn, places individuals at high risk for depression. The purpose of this study is to examine the feasibility and acceptability of a 12-week behavioral intervention that targets the timing and regularity of sleep, meals, and physical activity via digital monitoring and motivational health coaching. Participants were 60+ years of age and assessed on intervention acceptability and adherence, depression symptoms (Hamilton Rating Scale for Depr

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Davis, Fred C., and N. Viswanathan. "Stability of circadian timing with age in Syrian hamsters." American Journal of Physiology-Regulatory, Integrative and Comparative Physiology 275, no. 4 (1998): R960—R968. http://dx.doi.org/10.1152/ajpregu.1998.275.4.r960.

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The causes of age-related disruptions in the timing of human sleep and wakefulness are not known but may include changes in both the homeostatic and circadian regulation of sleep. In Syrian hamsters the free running period of the circadian activity/rest rhythm has been reported to shorten with age. Although this has been observed under a variety of experimental conditions, the changes have been small and their consistency uncertain. In the present study, the wheel running activity/rest rhythm was continuously measured in male Syrian hamsters ( Mesocricetus auratus) in dim constant light (<1

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Li, Xiao, Ka Sin Caroline Shea, Ching Kwong Dino Wong, et al. "624 The association of circadian rhythms with cognitive functioning in children with attention-deficit hyperactivity disorder." Sleep 44, Supplement_2 (2021): A245. http://dx.doi.org/10.1093/sleep/zsab072.622.

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Abstract Introduction Disrupted circadian rhythms is associated with impaired cognitive function. Although circadian rhythm disturbances are commonly seen in individuals with attention-deficit hyperactivity disorder (ADHD), whether their cognitive functioning is thus affected remains unclear. This study aimed to examine the associations of circadian-related parameters with different cognitive abilities in children with ADHD. Methods Fifty-seven children with ADHD were recruited into this study (age range: 6–12 years, 66.7% male). They were assessed by parent-report questionnaires on sleep prob

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Sultan, Armiya, Vivek Choudhary, and Arti Parganiha. "Characteristics of circadian rhythms in rest-activity and energy expendi-ture in cancer in-patients." South Asian Journal of Experimental Biology 4, no. 6 (2015): 327–35. http://dx.doi.org/10.38150/sajeb.4(6).p327-335.

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The objective of the current study was to assess the rest-activity (RA) and energy expenditure (EE) rhythms in cancer in-patients. Twenty chemothera-py receiving cancer in-patients (10 males and 10 females) and ten apparently healthy human subjects (5 males and 5 females) wore a non-invasive elec-tronic device – the Actical on their non dominant wrist. Data were recorded at 1-minute epoch for at least 3-4 consecutive days. Significant differences in RA and EE patterns were observed between cancer in-patients and control subjects, irrespective of gender. Control subjects showed absolute rhythm

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Yang, Hui-Wen, Sarah Chellappa, Arlen Gaba, Christian Cajochen, and Kun Hu. "758 Circadian rest-activity signatures in women with major depressive disorder." Sleep 44, Supplement_2 (2021): A295—A296. http://dx.doi.org/10.1093/sleep/zsab072.755.

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Abstract Introduction Patients with major depressive disorder (MDD) show disrupted circadian rhythms and sleep, including reduced daytime physical activity and poor sleep quality. However, previous findings are masked by psychotropic medication intake, co-morbid diseases and years of chronic mental illness. Here, we aim at identifying circadian motor activity patterns in unmedicated women at the onset of MDD. Methods Twelve young unmedicated women with MDD (Mean+-SD: 24.9+-5.2y; range: 18-33y) and eight age-matched healthy women (Mean+-SD: 24.5+-3.2y; range: 20-31y) participated in our study.

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Dowling, Glenna A., Erin M. Hubbard, Judy Mastick, Jay S. Luxenberg, Robert L. Burr, and Eus J. W. Van Someren. "Effect of morning bright light treatment for rest–activity disruption in institutionalized patients with severe Alzheimer's disease." International Psychogeriatrics 17, no. 2 (2005): 221–36. http://dx.doi.org/10.1017/s1041610205001584.

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Background: Disturbances in rest–activity rhythm are prominent and disabling symptoms in Alzheimer's disease (AD). Nighttime sleep is severely fragmented and daytime activity is disrupted by multiple napping episodes. In most institutional environments, light levels are very low and may not be sufficient to enable the circadian clock to entrain to the 24-hour day. The purpose of this randomized, placebo-controlled, clinical trial was to test the effectiveness of morning bright light therapy in reducing rest–activity (circadian) disruption in institutionalized patients with severe AD.Method: Su

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Innominato, Pasquale F., Oxana Palesh, Georg A. Bjarnason, Ayhan Ulusakarya, David Spiegel, and Francis Levi. "Symptoms associated with circadian rest-activity rhythm disruption in 237 patients with metastatic colorectal cancer." Journal of Clinical Oncology 33, no. 29_suppl (2015): 1. http://dx.doi.org/10.1200/jco.2015.33.29_suppl.1.

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1 Background: The circadian timing system exerts temporal control over physiology, generating rhythms of about 24 hours. Its alteration in benign conditions has been associated with several systemic symptoms, including fatigue, appetite loss and poor sleep. However, the clinical impact of circadian disruption in cancer patients remains overlooked. We hypothesized that patients with circadian disruption would report more severe symptoms than those with robust circadian function. Methods: Data were available for 237 patients with metastatic colorectal cancer: M/F ratio: 1.66; median age: 60.4 ye

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Liang, Huey-Wen, Chueh-Hung Wu, Chen Lin, et al. "Rest-Activity Rhythm Differences in Acute Rehabilitation Between Poststroke Patients and Non–Brain Disease Controls: Comparative Study." Journal of Medical Internet Research 26 (July 4, 2024): e49530. http://dx.doi.org/10.2196/49530.

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Background Circadian rhythm disruptions are a common concern for poststroke patients undergoing rehabilitation and might negatively impact their functional outcomes. Objective Our research aimed to uncover unique patterns and disruptions specific to poststroke rehabilitation patients and identify potential differences in specific rest-activity rhythm indicators when compared to inpatient controls with non–brain-related lesions, such as patients with spinal cord injuries. Methods We obtained a 7-day recording with a wearable actigraphy device from 25 poststroke patients (n=9, 36% women; median

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Levi, Francis, Sandra Komarzynski, Qi Huang, et al. "Relevance of real-time teletransmission of physical activity, sleep, and circadian rhythms from gastrointestinal cancer (GIC) patients (pts) during daily routine (IDEAs, IRAS 233972)." Journal of Clinical Oncology 38, no. 4_suppl (2020): 801. http://dx.doi.org/10.1200/jco.2020.38.4_suppl.801.

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801 Background: The relative amount of activity and rest over the 24-hours, as measured by the dichotomy index I < O from actimetry records, is an independent predictor of overall survival and quality of life, and an early warning signal for emergency hospitalisation. The IDEAs study aimed to determine the sleep, physical and circadian pathologies in pts during their daily routine at home, which could lower I < O and be modifiable through personalised interventions. Methods: The rest-activity and surface temperature patterns were monitored in real time using a tele-transmitting chest sen

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Leng, Y., T. Blackwell, P. M. Cawthon, S. Ancoli-Israel, K. Stone, and K. Yaffe. "1145 Longitudinal Association Between Circadian Activity Rhythms And Risk Of Incident Parkinson’s Disease In Older Men." Sleep 43, Supplement_1 (2020): A436. http://dx.doi.org/10.1093/sleep/zsaa056.1139.

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Abstract Introduction Disruption in circadian activity rhythms are very common in older adults, particularly among those with neurodegenerative diseases. However, the longitudinal association between circadian disruption and subsequent risk of developing neurodegenerative diseases, including Parkinson’s disease (PD), is unclear. Methods We examined rest-activity rhythms in 2930 community-dwelling older men (mean age 76.3 ± 5.5 years) without PD and followed them for incident PD over the next 11 years. 24-h rest-activity rhythm parameters (amplitude, mesor, robustness, acrophase) were generated

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Mesquita, Maria Eugênia, Maria Eliza Finazzi, Bruno Gonçalves, et al. "Activity/rest rhythm of depressed adolescents undergoing therapy: case studies." Trends in Psychiatry and Psychotherapy 38, no. 4 (2016): 216–20. http://dx.doi.org/10.1590/2237-6089-2015-0053.

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Abstract Introduction: Disorders of circadian rhythms have been reported in studies of both depressed children and of depressed adolescents. The aim of this study was to evaluate whether there is a relationship between the 24-hour spectral power (24h SP) of the activity/rest rhythm and the clinical course of depression in adolescents. Methods: Six 14 to 17-year-old adolescents were recruited for the study. They were all suffering from major depressive disorder, according to the Diagnostic and Statistical Manual of Mental Disorders, 4th edition (DSM-IV) criteria, as identified by the Schedule f

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Lévi, Francis, Sandra Komarzynski, Qi Huang, et al. "Tele-Monitoring of Cancer Patients’ Rhythms during Daily Life Identifies Actionable Determinants of Circadian and Sleep Disruption." Cancers 12, no. 7 (2020): 1938. http://dx.doi.org/10.3390/cancers12071938.

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The dichotomy index (I < O), a quantitative estimate of the circadian regulation of daytime activity and sleep, predicted overall cancer survival and emergency hospitalization, supporting its integration in a mHealth platform. Modifiable causes of I < O deterioration below 97.5%—(I < O)low—were sought in 25 gastrointestinal cancer patients and 33 age- and sex-stratified controls. Rest-activity and temperature were tele-monitored with a wireless chest sensor, while daily activities, meals, and sleep were self-reported for one week. Salivary cortisol rhythm and dim light melatonin onset

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Stefani, A. "0813 Circadian Rest-activity Rhythm In Isolated Rem Sleep Behavior Disorder." Sleep 43, Supplement_1 (2020): A309. http://dx.doi.org/10.1093/sleep/zsaa056.809.

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Abstract Introduction Isolated REM sleep behavior disorder (iRBD) is a parasomnia characterized by abnormal behaviours occurring during REM sleep. Several studies showed that iRBD is a prodromal stage of synucleinopathies. Therefore identifying iRBD in the general population is of utmost importance. Aim of this study was to explore whether the assessment of circadian rest-activity rhythm features, measured by actigraphy, can distinguish iRBD patients from patients suffering from disorders characterized by other pathological motor activity during sleep and healthy controls. Methods Nineteen sub

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Perrier, Joy, Melvin Galin, Pierre Denise, Bénédicte Giffard, and Gaëlle Quarck. "Tackling Insomnia Symptoms through Vestibular Stimulation in Patients with Breast Cancer: A Perspective Paper." Cancers 15, no. 11 (2023): 2904. http://dx.doi.org/10.3390/cancers15112904.

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Insomnia symptoms are common among patients with breast cancer (BC; 20–70%) and are predictors of cancer progression and quality of life. Studies have highlighted sleep structure modifications, including increased awakenings and reduced sleep efficiency and total sleep time. Such modifications may result from circadian rhythm alterations consistently reported in this pathology and known as carcinogenic factors, including lower melatonin levels, a flattened diurnal cortisol pattern, and lower rest-activity rhythm amplitude and robustness. Cognitive behavioral therapy and physical activity are t

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Sommer, Rosa, Lei Yu, Julie A. Schneider, David A. Bennett, Aron S. Buchman, and Andrew S. P. Lim. "Disrupted Rest-Activity Rhythms and Cerebral Small Vessel Disease Pathology in Older Adults." Stroke 52, no. 7 (2021): 2427–31. http://dx.doi.org/10.1161/strokeaha.120.030870.

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Background and Purpose: The pathogenesis of cerebral small vessel disease remains incompletely understood. The relationship between circadian rhythm disturbances and histopathologic measures of cerebral small vessel disease has not been studied. We hypothesized that disrupted circadian rest-activity rhythms would be associated with a higher burden of cerebral small vessel disease pathology. Methods: We studied 561 community-dwelling older adults (mean age at death, 91.2, 27.4% male) from the Rush Memory and Aging Project. We used actigraphy to quantify several measures of 24-hour rest-activity

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Alfini, Alfonso, Marilyn Albert, Andreia Faria, et al. "045 Associations of Actigraphic Sleep and Circadian Rest/Activity Rhythms with Cognition in the Early Phase of Alzheimer’s Disease." Sleep 44, Supplement_2 (2021): A19—A20. http://dx.doi.org/10.1093/sleep/zsab072.044.

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Abstract Introduction Alterations in sleep and circadian rhythms are common in persons with Alzheimer’s disease (AD) dementia, but the nature of such changes in the early phases of AD remains unclear. This study compared sleep and circadian rest/activity rhythms (RARs), measured by standard and novel actigraphic indices, between participants with normal cognition or mild cognitive impairment (MCI), and examined cross-sectional associations between these measures and cognition. Methods Actigraphy data were collected in 179 individuals (mean age=72.6 years, gender=64.8% female) with normal cogni

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