Thèses sur le sujet « Q-bit »
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Pimentel, Sobrinho Alvaro Caetano. « A contribuição do conceito do bit quântico(q-bit) para os fundamentos teóricos da ciência da informação ». Universidade Federal do Rio de Janeiro / Instituto Brasileiro de Informação em Ciência e Tecnologia, 2013. http://ridi.ibict.br/handle/123456789/670.
Texte intégralStudy about contributions of the concept of quantum bit (q-bit) and analyze the possibilities in quantum computers processing and increase the data storage capacity for devices memory. From the analysis of the q-bit is possible to notice changing in mental and social structures beyond their direct interference in the process of memory as a way of preserving information in different formats. Observations in the contributions from Quantum Mechanics, by measuring process, for Information Science and theoretical-epistemic confluence between the two sciences complemented by some opinions around the issues that still needing answer. Insertion of terms entanglement and superposition that were identified as fundamental to understanding the concept of q-bit is the basis to accept the updates in the concepts, formulations and descriptions established in Information Science
Estudo das contribuições do conceito do bit quântico (q-bit) e suas possibilidades de processamento nos computadores quânticos e de aumento da capacidade de armazenamento dos dados em dispositivos de memória. A partir da análise do q-bit, é possível a percepção das alterações de estruturas mentais e sociais, além de sua interferência direta no processo de memória como meio de preservação de informações sob diversos formatos. Observações das contribuições a Mecânica Quântica para a Ciência da Informação e a confluência teórico epistêmica entre as duas ciências, complementadas por algumas ponderações em torno das questões que ainda necessitam de respostas. Inserção dos termos emaranhamento e superposição de estados identificados como fundamentais para o entendimento do conceito de q-bit. Tais termos são a base para dimensionar as alterações em conceitos, formulações e descrições consagrados na Ciência da Informação. Palavras-chave: Bit quântico
Healey, Joanne E. « Experiments to develop High Q and tunable superconducting coplanar resonators applicable for quantum bit technology ». Thesis, University of Birmingham, 2010. http://etheses.bham.ac.uk//id/eprint/1077/.
Texte intégralRaimondo, Gianluca. « Particle mixing, two level systems and gauge theory ». Doctoral thesis, Universita degli studi di Salerno, 2012. http://hdl.handle.net/10556/1304.
Texte intégralIn this thesis I will discuss the theory of two level systems and the theory of the oscillating particles in quantum eld theory. In the rst chapter I will consider the time evolution of a two level system, a qubit, to show that it has inside a local in time gauge invariant evolution equation. I construct the covariant derivative operator and show that it is related to the free energy. The gauge invariance of the time evolution of the two level system is analogous to the phenomenon of birefringence.I also show that the two level systems present a Berry-like and an Anandan-Aharonov phase. Finally, I discuss entropy environment e ects and the distance in projective Hilbert space between two level states to show that the last one is properly related to the Aharonov - Anandan phase. In the second chapter I review the result obtained in QFT for particle mix- ing, analyzing the theoretical construction and the oscillation formula in the fermion case.I will emphasize the di erences between the quantum mechan- ics formulas and the QFT formulas.The unitary inequivalence between the avor and the mass eigenstates is also shown and the structure of the current for charged elds is nally discussed. I found a non - perturbative vacuum structure for the mixing particles that, among the other things, will lead to a non zero contribution to the value of the cosmological constant (chapter 3). Several links between rst and second chapter will arise from this thesis and will shed the light on the fact that it is possible to construct a generic two level quantum eld theory, that is an extension of the quantum mechanics bit theory in a quantum eld theory framework. [edited by author]
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Neto, Domingos Soares. « Filtros para a busca e extração de padrões aproximados em cadeias biológicas ». Universidade de São Paulo, 2008. http://www.teses.usp.br/teses/disponiveis/45/45134/tde-19102009-002745/.
Texte intégralThis thesis deals with computational formulations and algorithms for the extraction and search of patterns from biological strings. In particular, the present text focuses on the following problems, both considered under Hamming and Levenshtein distances: 1. How to find the positions where a given pattern approximatelly occurs in a given string; 2. How to extract patterns which approximatelly occurs in a certain number of strings from a given set. The first problem, for which there are many polinomial time algorithms, has been receiving a lot of attention since the 60s and entered a new era of discoveries with the advent of computational biology, in the 80s, and the widespread of the Internet and its search engines: both events brought new challenges to be faced by virtue of the large volume of data usually held by such applications and its time constraints. The second problem, much younger, is very challenging due to its computational complexity, approximation hardness and the size of the input data usually held by the most common applications. This problem is also very interesting due to its potential of application. In this work we show computational formulations, algorithms and data structures for those problems. We cover the bit-parallel algorithms of Myers, Baeza-Yates-Gonnet and the Sagots algorithms for patterns extraction. We also cover here the oustanding versatile suffix tree, its generalised version, and a similar data structure: the suffix array. A significant part of the present work focuses on q-gram based filters designed to solve the approximate pattern search problem. More precisely, we cover the filter algorithms of Ukkonen, Jokinen-Ukkonen and Burkhardt-Kärkkäinen, among others.
Peloušek, Tomáš. « Simulace zkreslení zvukového signálu v percepčním zvukovém kodéru ». Master's thesis, Vysoké učení technické v Brně. Fakulta elektrotechniky a komunikačních technologií, 2021. http://www.nusl.cz/ntk/nusl-442567.
Texte intégralWang, Hanlin. « The Economic Phenomena of Net Games and of Bit Coins in China ». Master's thesis, Vysoká škola ekonomická v Praze, 2013. http://www.nusl.cz/ntk/nusl-193137.
Texte intégralLundin, Carl. « Rapid transit and property values ». Thesis, KTH, Fastigheter och byggande, 2014. http://urn.kb.se/resolve?urn=urn:nbn:se:kth:diva-146890.
Texte intégralThis thesis delves deeply into the expansion of the Stockholm subway to Nacka municipality. The purpose has been to investigate whether there is a change in the valuation of properties in close proximity to new or expanded subway. The theory chapter covers different theories on land use and bid rent curves. The theories are based on von Thünen’s way of describing land use. The thesis goes through how the willingness to pay for land on one hand differs between different property types and on another hand decreases with distance to Central Business District (CBD). Offices and retail have a relatively higher willingness to pay for land in the proximity of CBD than residential and residential have a higher willingness to pay than industrial. With increased availability thanks to subway come numerous unique areas (local CBD’s) where office and retail have a higher willingness to establish. The increased availability also heightens the Tobin’s Q, which means we can expect a higher degree of exploitation. 15 academic papers that cover the issue are analyzed. The articles which are the basis for the reasoning on value change have studied rapid transit systems and conducted analysis on sales data. The average increase in property value of 9,6 %. The articles also gives good input on negative externalities (which however never exceeds the benefits), for example increased criminality. The participants in the survey are expecting that all types of properties will increase in value within a radius of 1 kilometer from the stations. They consider that there is a potential market for private co-financing and that middle-class areas are the ones with highest willingness to pay for subway.
Amsanpally, Abhilash. « Linear properties of inhibited coupling hollow-core photonic crystal fibers ». Thesis, Limoges, 2017. http://www.theses.fr/2017LIMO0028/document.
Texte intégralThis thesis reported on guiding principles, linear properties and conceptual design tools of inhibited coupling (IC) guiding hollow-core photonic crystal fibers (HC-PCF). IC guidance was proved as photonic manifestation of Q-BiC (quasi bound-state-in-a-continuum) by investigating asymmetric and polarization dependent Fano profiles with bandwidth of 30 GHz in high resolution transmission spectra. By using IC design concept, we reported on linear characterization of state-of-the-art IC HC-PCFs. Based on core shaping optimization, a Kagome IC HC-PCF demonstrated ultra-low loss down to 8.5 km/km at 1030 nm associated with a 225 nm wide 3-dB bandwidth. Another Kagome design with thinner silica struts of 300 nm exhibited lowest loss of 30 dB/km at 780 nm along with record level fundamental bandwidth spreading down to 670 nm and able to cover the entire Ti:Sa, Yb and Er laser spectral ranges. We also reported on design and fabrication of single-ring tubular lattice IC HC-PCFs. One of these fibers demonstrated transmission down to 220 nm with a record transmission loss of 7.7 dB/km at ~750 nm, while the second one exhibited ultra-broad fundamental band with loss range of 10-20 dB/km over one octave spanning from 600 to 1200 nm. Finally, the second tubular fiber was further investigated for fundamental loss sources due to surface roughness around its core-contour
Fluckinger, Chris D. « Measurement of Big Five Personality via Q-Sort : Comparison with a Likert Measure and Test-Taker Perceptions and Reactions ». University of Akron / OhioLINK, 2010. http://rave.ohiolink.edu/etdc/view?acc_num=akron1279038683.
Texte intégralAlbuquerque, Rosângela Marques de. « Obtenção de portas lógicas quânticas em condensados de bose-einstein ». reponame:Repositório Institucional da UFC, 2017. http://www.repositorio.ufc.br/handle/riufc/27051.
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Bose-Einstein condensate (BEC) coupled is a promising candidate to quantum computing. Being a macroscopic quantum phenomenon, Being a strong quantum system (BÖIH et al., 2009), its assembly and experimental control inside an atomic chip (HÄNSEL et al.,2001), further the optical networks (GREINER OLAF MANDEL, 2001), where it is found and manipulated in different network sites, assuring implementation conditions of Quantum Information Protocol. The definition of a Qubit in BECs was proposed considering the couple of two BEC’s in different hyperfine states throught a two-photon transition. We have identified each one of the condensates in their respective hyperfine levels like the states and the Qubit. Experimentally, it is possible both the identification of atoms that ate in each one of the hyperfine levels and the measurement of the condensate phase. With these information is possible to determine the superposition coefficients . In this coursework, we have studied the dynamics of two Bose-Einstein condensate (BEC) on its fundamental state, trapped and coupled by a quantum tunneling. Because of this coupling, there is population transference between two condensed modes. The coupling is adjusted in a way we have probability of occupation in two levels. We have shown that this system can be considerate viable to a Qubit. So, we have simulated the quantum gates NOT and Hadamard.
Condensados de Bose-Einstein (CBE) acoplados é candidato promissor à computação quântica. Por ser um fenômeno quântico macroscópico, por ser um sistema quântico robusto (BÖHI et al., 2009), por sua montagem e controle experimental dentro de um chip atômico (HÄNSEL et al., 2001), além das construções em redes ópticas (GREINER OLAF MANDEL, 2001), onde são localizados e manipulados em diferentes sítios da rede, garantindo condições de implementação de protocolos de Informação Quântica. A definição de um q-bit em CBEs foi proposta considerando o acoplamento de dois CBEs em diferentes estados hiperfinos através de uma transição de dois fótons. Identificamos cada um dos condensados nos seus respectivos níveis hiperfinos como os estados j0i e j1i do q-bit. Experimentalmente, é possível tanto a identificação dos átomos que estão em cada um dos níveis hiperfinos quanto a medição da fase dos condensados. Com estas informações é possível determinar os coeficientes de superposição a j0i+b j1i. No presente trabalho, estudamos a dinâmica de dois condensados de Bose - Eisntein (CBE) no estado fundamental, armadilhados e acoplados por tunelamento quântico. Devido a esse acoplamento, há transferência de população entre os dois modos condensados. O acoplamento é ajustado de maneira que tenhamos probabilidade de ocupação em dois níveis. Demonstramos que este sistema pode ser considerado viável a um q-bit. Então, simulamos as portas quânticas NOT e Hadamard.
Brasil, Carlos Alexandre. « Tomografia de estados quânticos em sistemas de 3 q-bits : uma ferramenta da ressonância magnética nuclear para aplicações em computação quântica ». Universidade de São Paulo, 2008. http://www.teses.usp.br/teses/disponiveis/76/76131/tde-01042008-145626/.
Texte intégralThis work describes a quantum state tomography method in nuclear magnetic resonance using nonselective radiofrequency pulses that cause global rotations of spin 7/2 systems. This method was applied to tomograph states related to quantum computation. Numerically optimized modulated pulses allowed building the initial states and the logical operations involved in the quantum operations; particularly, the optimization process was not treated in this work. Several programs were constructed that simulate: o the construction of the quantum states and the logical operations by means of the modulated pulses parameters; o the application of the tomography pulses and the generation of the necessary data for tomography (spectral amplitudes); o the construction of the states using simple pulses for experimental condition tests; o the effects of possible problems related to the samples or equipments. Finally, a quantum state tomography program was elaborated to read the spectral amplitudes, which can be obtained from the programs related to the second item, or experimentally. The experimental implementations were performed measuring the NMR signals from spin 7/2 133Cs nuclei located in a liquid crystal under Zeeman and quadrupolar electric interactions. The NMR spectrum of these nuclei, under these interactions and located in an oriented sample, present 7 spectral lines for transitions between adjacent energetic levels; with this, it is possible to treat it like a 3 q-bits system. Pseudo-pure states were constructed and one Toffoli gate was applied. Furthermore, a discussion about the Grover\'s quantum search algorithm in the nuclear magnetic resonance context was presented for future implementation.
Jonsson, Emma, et Marja-Lena Nieminen. « Killar och tjejers faktorstruktur i personlighetsformuläret Pers Q ». Thesis, Örebro University, Department of Behavioural, Social and Legal Sciences, 2006. http://urn.kb.se/resolve?urn=urn:nbn:se:oru:diva-590.
Texte intégralSyftet med studien är att undersöka om det nya personlighetsformuläret Pers Q fungerar på ungdomar samt studera eventuella könsskillnader i personlighet. Vidare undersöks om bakgrundsvariablerna årskurs, syskonplacering, sociokulturell bakgrund samt självuppskattad skolprestation har samband med personligheten. Studien är ett led i utprövningen av Pers Q som mäter verifierade personlighetsfaktorer med validitet för arbetskriterier. Respondenterna består av 138 killar och 233 tjejer från gymnasiet (n=371). En explorativ principalkomponentanalys verifierade en tidigare faktorstruktur med sju personlighetsfaktorer: Omtanke om andra (alfa ,87), Noggrannhet (,84), Social förmåga (,84), Kreativitet (,82), Humörinstabilitet (,77), Stresstålighet (,76) samt Självförtroende (,72). Resultatet visar signifikanta könsskillnader i fem av sju faktorindex. Slutresultatet visar att Pers Q är ett snabbt och lätthanterligt personlighetsformulär som fungerar väl på ungdomar.
Wikby, Pierre, et Ragnar Andersson. « Strukturgeologisk karaktärisering av Getåravinen : En visualisering av lineamentsstudie med prediktioner och modellering inför Ostlänken ». Thesis, KTH, Hållbar utveckling, miljövetenskap och teknik, 2018. http://urn.kb.se/resolve?urn=urn:nbn:se:kth:diva-230782.
Texte intégralThe East Link is a planned high-speed rail link between Järna and Linköping with a gradual construction start in 2017, a comprehensive project covering a total of approximately 20 kilometers of tunnel, of which one tunnel is planned to cross the Getå ravine. Subsurface construction is complicated, and contact with weak zones in the rock implies increased risks for the tunnel construction, the environment and the surrounding real estates. In order to accomplish a risk assessment, dimensioning and economic calculation, geological engineering investigations of the rock’s quality and geological structure are carried out. Studies have shown a relationship between natural lineaments and weaknesses in the rock. Therefore, the purpose of this thesis was to assess geological constructability factors in the Getå ravine by using a characterization of structural geology. The focus was within a demarcated area where the consulting firm Sweco, on behalf of the Swedish Transport Administration, had performed engineering geological surveys for the planned construction of the East link.The thesis was based on a study of lineament in geological maps, core drill samples and bedrock mapping in the surroundings of the Getå ravine, which were later analysed to identify structural geological relations. The methods Inverse Distance Weighted and Kriging were used to predict the rock ambient to the core kernels based on the quality ratings Rock Mass Rating, Q System and Rock Quality Designation. In order to visualize the results pedagogically and enhance the basis for technical discussion regarding civil engineering, the results were visualized in a Building Information Model in the software AutoCAD Civil 3D. The result showed approximately 20° deviation between the lineament and the primary joint strike in the Getå ravine, it confirmed a joint pattern that can be generally assumed for natural lineaments which is useful information in subsurface construction. The predictions showed a spatial distribution of the rock's different quality ratings and relationship with the lineament. The utility of the predictive methods was therefore certain because of efficient quantification of the rock quality was made possible, which can be implemented when characterizing the rock into quality domains prior subsurface construction.
Carlesi, Lorenzo. « Socio-Economic Analysis of Mediterranean Deep-Sea Ecosystem Goods and Services ». Doctoral thesis, Università Politecnica delle Marche, 2016. http://hdl.handle.net/11566/243090.
Texte intégralThe deep sea represents the largest (but the least explored) biome on Earth. It is increasingly affected by anthropogenic stressors and climate changes, threatening the provision of crucial ecosystem services in the future. The monetary value of those benefits remains scarcely assessed. The deep sea and, more generally, oceans host a high biodiversity. A great variability in the people’s willingness to pay (WTP) for marine biodiversity emerges from the literature. Price vector, investigated species and location of studies represent the variables that most influence such WTP. Non-linear relationships between the WTP and most of the explaining variables are observed. A better understanding of people’s perception of deep sea may support its (non-market) valuation. Applying Q methodology, different perspectives on Mediterranean deep sea are revealed. The importance attributed to species and habitats vary between the points of view. The use of different conditions of instruction and the respondents’ expertise are important factors in determining the perception of Mediterranean deep sea, even if they cannot completely explain the participants’ subjectivity. A great heterogeneity in the preference of Italian citizens for preserving the Mediterranean deep sea emerges from a discrete choice experiment. Many respondents refuse to pay for supporting the protection of biodiversity and the scientific research on that remote and unfamiliar environment. By contrast, participants with a high awareness of the importance of natural resources are willing to pay for protecting, in particular, deep-water corals. High income and past donations for environmental protection positively influence the respondents’ willingness to fund further scientific researches on the Mediterranean deep sea. Overall, the global warming is of little concern for the participants, who are not willing to pay for limiting the temperature rise.
Urbani, Andrea. « Mechanisms of induction and propagation of cortical spreading depression in mouse brain slices ». Doctoral thesis, Università degli studi di Padova, 2012. http://hdl.handle.net/11577/3422971.
Texte intégralL’emicrania è un disturbo neurologico comune ed altamente invalidante che colpisce più del 10% della popolazione in generale; nel 30% dei pazienti affetti da emicrania, la fase del dolore è preceduta da sintomi neurologici transienti definiti nel complesso “aura emicranica”. L’emicrania emiplegica familiare di tipo 1 (FHM1) è una forma autosomica dominante di emicrania con aura rara ma molto grave; l’FHM1 è considerata un buon modello per lo studio dell’emicrania: gli attacchi tipici di FHM1, infatti, ricapitolano molto quelli della normale emicrania con aura, tuttavia durante l’aura si presentano sintomi come debolezza motoria o paralisi, spesso ma non sempre unilaterale. L’FHM1 è dovuta a mutazioni nel gene CACNA1A che codifica la subunità α1 formante il poro dei canali Ca2+ neuronali voltaggio dipendenti CaV2.1, chiamati anche canali per il calcio di tipo P/Q. Le mutazioni FHM1 producono un guadagno di funzione dei canali ricombinanti umani CaV2.1; tale guadagno di funzione è principalmente dovuto allo spostamento della curva di attivazione del canale verso valori di potenziale più negativi e all’aumento della probabilità di apertura e dell’influsso di Ca2+ a livello di singolo canale in un ampio intervallo di potenziali vicini alla soglia di attivazione del canale (Hans et al., 1999; Tottene et al., 2002, 2005). Studi in vivo (van den Maagdenberg et al., 2004) ed in vitro (Tottene et al., 2009) hanno dimostrato come topi knock-in (KI) per la mutazione umana FHM1 R192Q presentino una facilitazione nell’induzione sperimentale della cortical spreading depression, il fenomeno neurologico alla base dell’aura emicranica e possibile evento innescante il tipico mal di testa caratterizzante l’emicrania. Dal punto di vista elettrico la CSD è un’onda di forte depolarizzazione neuronale e gliale, che si propaga lentamente attraverso la corteccia cerebrale ed è seguita da una lunga fase di soppressione neurale. Recentemente Tottene e colleghi (2009) hanno dimostrato un aumento nella trasmissione sinaptica eccitatatoria corticale dei topi FHM1 R192Q; tale aumento è dovuto all’aumentato influsso di Ca2+ evocato da potenziali d’azione attraverso i canali CaV2.1 ed al conseguente aumento nella probabilità di rilascio del neurotrasmettitore glutammato alle sinapsi piramidali di questi topi. Attraverso l’impiego di un modello in vitro, Tottene e colleghi hanno, inoltre, dimostrato il rapporto di causalità tra l’aumentato rilascio di glutammato dai neuroni piramidali e la facilitazione nell’induzione della CSD tramite brevi applicazioni pressorie di KCl a concentrazioni elevate in fettine di cervello da questi topi. Tali evidenze supportano l’ipotesi di un ruolo chiave dei canali CaV2.1 nei meccanismi di induzione e propagazione della CSD. La prima parte del mio progetto di dottorato ha avuto come scopo fondamentale l’approfondimento delle conoscenze riguardo i meccanismi che sottendono induzione e la propagazione della CSD; in particolare il mio interesse si è principalmente soffermato sul ruolo dei canali del calcio voltaggio-dipendenti e dei recettori NMDA. I risultati ottenuti sono stati pubblicati (Tottene et al., 2001, pdf allegato nel capitolo 3). Per conseguire gli scopi prefissi abbiamo impiegato il modello in vitro già in precedenza adottato da Tottene e colleghi (2009) ed abbiamo misurato la soglia di induzione della CSD e la velocità di propagazione della stessa in fettine corticali di topo wild-type (WT) prima e dopo l’applicazione di vari inibitori selettivi dei canali d’interesse. La durata del primo impulso in grado di indurre una CSD veniva considerata la soglia di induzione della stessa, mentre la velocità di propagazione della CSD coincideva con la velocità di propagazione dei cambiamenti nel segnale ottico intrinseco (IOS) associati ad essa. Il ruolo dei recettori NMDA è stato indagato mediante l’impiego di un inibitore selettivo in concentrazione saturante: D-AP5, 50 µM. In presenza di D-AP5 stimoli fino a 30 volte la soglia controllo non erano in grado di indurre una CSD. Abbiamo inoltre indagato il ruolo dei canali per il Ca2+ voltaggio-dipendenti di tipo P/Q, N, R ed L, usando i rispettivi inibitori specifici: ω-agatossina IVA (300 nM), ω-conotossina GVIA (1 μM), SNX-482 (250 nM) e nimodipina (50 μM). Similmente a quanto osservato in presenza di D-AP5, in presenza di ω-AgaIVA, stimoli fino a 30 volte la soglia controllo non erano in grado di indurre una CSD. Diversamente, l’applicazione di ω-CgTxGVIA o di SNX-482 provocava un lieve innalzamento della soglia (di circa il 10%) e una leggera diminuzione della velocità (di circa il 15%), suggerendo un ruolo modulatore dei canali per il calcio voltaggio-dipendenti di tipo N ed R nell’induzione e nella propagazione della CSD. Al contrario l’applicazione di nimodipina non aveva alcun effetto sulla soglia o sulla velocità della CSD. La dimostrazione che D-AP5 e ω-AgaIVA sono in grado di inibire totalmente l'induzione e la propagazione della CSD, mentre CgTxGVIA, SNX-482 e nimodipina presentano solo un lieve effetto, o nessun effetto, sono consistenti con ed avvalorano un modello di induzione e propagazione della CSD nel quale l’attivazione dei canali CaV2.1 presinaptici (e forse anche di quelli postsinaptici) e dei recettori NMDA ha un ruolo essenziale (Tottene et al., 2011). Il ruolo dei recettori NMDA è stato ulteriormente indagato, sfruttando i topi KI FKM1 R192Q, che presentano un incrementato rilascio di glutammato da parte dei neuroni piramidali. Contrariamente a quanto riscontrato nei WT, in questi topi l’applicazione di D-PA5 non era in grado di bloccare l’induzione della CSD, ma aumentava invece significativamente la soglia (90 ± 9%) e diminuiva significativamente la velocità (47 ± 1%) rispetto al controllo. Il diverso effetto del D-AP5 riscontrato nei topi WT ed in quelli KI potrebbe suggerire che altri elementi (oltre ai recettori NMDA) potrebbero essere coinvolti nell’induzione e nella propagazione della CSD. Registrazioni in current-clamp in prossimità del sito di eiezione del KCl, alle distanze fisse di 100 e 200 µm, hanno permesso di osservare e distinguere diverse fasi nei cambiamenti di voltaggio indotti dall’applicazione di stimoli di KCl sottosoglia e a soglia; è stato infatti possibile osservare la presenza di tre diversi picchi. Mentre i primi due picchi erano condivisi dalle depolarizzazioni sottosoglia e dalla CSD, la comparsa del terzo picco era specificamente legata all’induzione della CSD. La tecnica del patch-clamp ha permesso di descrivere nel dettaglio le diverse fasi di depolarizzazione, mostrando tuttavia l’ovvia restrizione di limitare l’osservazione ad una sola cellula per volta. Il Ca2+ imaging di fettine caricate con l’indicatore Ca2+ sensibile OGB1-AM ha invece permesso di monitorare allo stesso tempo diversi neuroni a diverse distanze dalla pipetta iniettante KCl dopo lo stesso stimolo. L’esecuzione simultanea di patch clamp e Ca2+ imaging nella stessa fettina ha dimostrato una generale correlazione tra le diverse fasi dei cambiamento di voltaggio registrate in current-clamp ed i picchi nelle tracce di fluorescenza. I possibili significati fisiologici e gli eventuali ruoli nell’induzione e nella propagazione della CSD di queste diverse fasi non sono ancora chiari e sono al momento attuale oggetto di studio nel laboratorio dove ho svolto la mia attività di ricerca. Gli esperimenti di Ca2+ imaging hanno permesso, oltre a quanto già descritto, di osservare incrementi nella concentrazione intracellulare di Ca2+ degli astrociti in risposta agli stimoli di KCl. Gli astrociti possono sostenere ed amplificare la trasmissione eccitatoria glutamatergica tramite rilascio di glutammato che agisce specificamente sui recettori NMDA; il rilascio di glutammato e di altre sostanze da parte degli astrociti è indotto da innalzamenti nella [Ca2+]int, causati a loro volta dal rilascio di diversi neurotrasmettitori (tra cui il glutammato) da parte dei neuroni. Per verificare se la comunicazione reciproca tra neuroni ed astrociti possa essere coinvolta nell’induzione e nella propagazione della CSD, la soglia e la velocità della CSD sono state misurate prima e dopo l’inibizione degli aumenti di Ca2+ intracellulare tramite applicazione di acido ciclopiazonico (CPA, 50 µM), in grado di svuotare gli stores di Ca2+ intracellulari senza influenzare la risposta dei neuroni al KCl. L’applicazione di CPA non influenzava né la soglia di induzione della CSD, né la velocità di propagazione sia nei topi WT che nei topi KI. Questi risultati suggeriscono che l’intercomunicazione tra neuroni ed astrociti non sia rilevante per l’induzione e la propagazione della CSD. La combinazione di Ca2+ imaging e patch clamp ha permesso l’osservazione, in assenza di stimolazione esterna, di attività spontanea che avviene normalmente nei networks neurali della neocorteccia; tale attività si presenta come oscillazioni lente tra periodi di depolarizzazioni indotte da attività sinaptica associate all’insorgenza di potenziali d’azione (up-states) e tra altri periodi in cui l’attività sinaptica diminuisce ed il firing scompare (down-states). Allo stesso tempo è stato possibile osservare la presenza di intense oscillazioni spontanee nella [Ca2+]int degli astrociti. Per verificare se la comunicazione reciproca tra neuroni ed astrociti potesse essere coinvolta nella generazione o nella modulazione dell’attività spontanea neuronale di network, tali oscillazioni spontanee degli astrociti sono state soppresse tramite l’applicazione di CPA. In presenza di CPA gli up-states neuronali erano ancora presenti sia nei topi WT, che nei KI, tuttavia nel primo caso si assisteva ad una riduzione significativa nella frequenza degli up-states (41 ± 3%, p = 0.0001), non riscontrabile nel caso dei topi KI (11 ± 6%, p = 0.12). Questi risultai preliminari sono in accordo con un possibile ruolo dell’intercomunicazione tra neuroni ed astrociti nell’attività spontanea dei network neuronali
Agyo, Sanfo David. « Bi-fractional transforms in phase space ». Thesis, University of Bradford, 2016. http://hdl.handle.net/10454/14522.
Texte intégralAgyo, Sanfo D. « Bi-fractional transforms in phase space ». Thesis, University of Bradford, 2016. http://hdl.handle.net/10454/14522.
Texte intégralSabra, Mostafa. « Développement de lasers à fibres thulium bi-fréquences à impulsions synchrones pour la réalisation de sources Térahertz ». Thesis, Limoges, 2019. http://www.theses.fr/2019LIMO0118.
Texte intégralAs part of a collaborative project between the XLIM laboratory (UMR 7252 of the CNRS and the University of Limoges) and the IPHT research laboratory located in Jena, Germany, my thesis project consists in the development of a widely tunable dual-wavelength synchronous pulsed thulium doped fiber laser for the realization of an efficient and tunable terahertz source. Based on the use of two volume Bragg gratings (VBGs) and a double-clad, polarization-maintaining thulium doped fiber (core diameter = 20 μm) manufactured by the REPUSIL method, a widely tunable single-wavelength laser and dual-wavelength laser has been realized and studied in continuous regime. A tunability of 1 nm to 144 nm was obtained with a power more than 4.5 W and a good signal-to-noise contrast (~ 45 dB) and a spectral linewidth less than 0.1 nm. In pulse regime, an acousto-optic modulator (AOM) was used in free space in the laser cavity to generate the pulses. The double-clad fiber has been replaced by a large-core thulium doped fiber (40 μm) called FA-LPF to to fend off the threshold of non-linear effects and work with a short fiber to decrease the pulse duration and increase the peak power of the obtained pulses. A widely tunable (from 3.8 nm to 120 nm) Q-switched dual-wavelength synchronous-pulsed thulium-doped fiber laser was developed with a peak power more than 8 kW and a pulse duration around 26 ns obtained independently of the value of Δλ at 1 kHz of repetition rate. A contrast higher than 20 dB was obtained limited by the FWM peaks generated for Δλ values below 45 nm. The spectral linewidth of the laser measured at 3 dB of the maximum was less than 0.3 nm
Cheng, Tsai-Wen, et 鄭採文. « A Low-power High-speed 8-bit Pipelining CLA Design Using Dual Threshold Voltage Domino Logic and Low-cost Digital I/Q Separator for DVB-T ». Thesis, 2006. http://ndltd.ncl.edu.tw/handle/15732239599200597417.
Texte intégral國立中山大學
電機工程學系研究所
94
This thesis includes two topics. One is a low-power high-speed 8-bit pipelining CLA design using dual threshold voltage (dual- Vth) domino logic. The other is a low-cost digital I/Q separator for DVB-T receivers. A high speed and low power 8-bit CLA using dual- Vth domino logic blocks arranged in a PLA-like style with pipelining is presented. According to parallely precharge and sequentially evaluate in a cascaded set of domino logic blocks, transistors in the precharge part and the evaluation part of dual- Vth domino logic are, respectively, replaced by high Vth transistors to reduce subthreshold leakage current through OFF transistors, and low Vth transistors. Moreover, an nMOS transistor is inserted in the precharge phase of the output inverter such that the two-phase dual- Vth domino logic can be properly applied in a pipeline structure. Consequently, the proposed design keeps the advantage of high speed while attaining the effect of low power dissipation. A low-cost digital I/Q separator is presented in the second part of this thesis. Using digital I/Q separator in place of the traditional analog I/Q separator guarantees the design conquer gain and phase mismatch problems between the I and Q channels. The proposed design can berealized by inverters and shifters such that the goal of low cost can be achieved.
Klöckl, Ingo [Verfasser]. « Messung von Qβ-Werten [Q-beta-Werten] neutronenreicher Tc- bis Pd-Isotope im Massenbereich A=110 bis A=117 / Ingo Klöckl ». 2008. http://d-nb.info/990694798/34.
Texte intégral« Built-in-Self Test of Transmitter I/Q Mismatch and Nonlinearities Using Self-Mixing Envelope Detector ». Master's thesis, 2012. http://hdl.handle.net/2286/R.I.15094.
Texte intégralDissertation/Thesis
M.S. Electrical Engineering 2012