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Articles de revues sur le sujet "Pulmonary functional testing"

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Jeong, Yoon Jeong, Gyu Seong Kim, Yeon Gyu Jeong et Hyun Im Moon. « Can Pulmonary Function Testing Predict the Functional Outcomes of Poststroke Patients ? » American Journal of Physical Medicine & ; Rehabilitation 99, no 12 (23 juin 2020) : 1145–49. http://dx.doi.org/10.1097/phm.0000000000001507.

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Varon, Joseph, Sushen Bhalla et Daniel Martini. « Long-Haul COVID-19 : Imaging or Functional Testing ? » Current Respiratory Medicine Reviews 18, no 3 (août 2022) : 159–60. http://dx.doi.org/10.2174/1573398x1803220810153544.

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Yeh, Mei-Ling, Hsing-Hsia Chen, Yu-Chien Liao et Wei-Yu Liao. « Testing the functional status model in patients with chronic obstructive pulmonary disease ». Journal of Advanced Nursing 48, no 4 (novembre 2004) : 342–50. http://dx.doi.org/10.1111/j.1365-2648.2004.03203.x.

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Valieva, Z. S., Z. H. Dadacheva, T. V. Martynyuk, N. M. Danilov, M. A. Saidova et I. Ye Chazova. « CLINICAL CASE : THERAPY WITH SILDENAFIL IN THE TREATMENT OF IDIOPATHIC PULMONARY HYPERTENSION ». Eurasian heart journal, no 4 (30 décembre 2015) : 40–47. http://dx.doi.org/10.38109/2225-1685-2015-4-40-47.

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The patient with the verified diagnosis of idiopathic pulmonary hypertension, negative acute vasoreactivity testing by RHC, functional class III (WHO) was treated by phosphodiesterase type 5 inhibitor sildenafil. After one year there was achieved the significant improvement of the functional and hemodynamic status.
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Copelan., Edward A. « Predicitve Value of Pretransplant Testing. » Blood 104, no 11 (16 novembre 2004) : 1144. http://dx.doi.org/10.1182/blood.v104.11.1144.1144.

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Abstract Routine evaluation prior to stem cell transplantation generally includes assessment of left ventricular ejection fraction (EF), pulmonary function, renal function, liver function, and functional status. Patients in whom compromised organ function is detected, are often deemed ineligible for myeloablative transplantation. However, the predictive value of specific pretransplant tests is not well documented, and has not been critically analyzed in patients receiving busulfan-based preparative regimens. We analyzed the prognostic value of the pretransplant evaluation performed in 1035 consecutive patients who underwent autologous (n=444) or allogeneic (n=591) transplantation with busulfan-based regimens between 2/84 and 12/03 for acute (250) or chronic leukemia (198), myelodysplasia (50), multiple myeloma (88), or Hodgkin’s (139) or non-Hodgkin’s lymphoma (303). Ages ranged from 4–75 (median 41). BuCy was given to 477 and BuCyVP16 to 558 individuals. Ninety three patients had EF < 50%, 61 had DLCO < 65%, 103 had elevated creatine, 130 had elevated tranaminases or bilirubin, and 116 had Karnofsky scores < 80%. For the entire group, multivariable analysis demonstrated only Karnofsky score < 80% (P < .001) and elevated LFTs (P=.04) to have significant adverse prognostic influence on survival. Karnofsky score was significant in patients undergoing autologous (P <.001) or allogenic (P <.001) transplantation. Neither EF nor DLCO were predictive of poor outcome for the overall group (P >.2), nor for the autologous or allogeneic transplant groups. However in patients undergoing transplants from unrelated donors (n=119) DLCO < 65% was a significant adverse prognostic factor (P=.004). There was no association of compromised cardiac or pulmonary function with cardiac or pulmonary failure as a primary cause of death. This study suggests that moderately compromised organ function, particularly cardiopulmonary limitations which might not be clinically apparent, are of limited value in prediction of transplant outcome. Direct clinical assessment, including functional status are of much greater value in prediction of outcome. It is hoped that this investigation will stimulate larger studies of pretransplant predictors of outcome with attention to their relevance to specific preparative regimens, sources of stem cells, and other treatment variables.
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Pele, Irina, et Florin-Dumitru Mihălțan. « Cardiopulmonary exercise testing in thoracic surgery ». Pneumologia 69, no 1 (27 juillet 2020) : 3–10. http://dx.doi.org/10.2478/pneum-2020-0001.

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AbstractThe assessment of functional capacity is a significant part of the preoperative evaluation of patients proposed for both thoracic and abdominal surgery. The cardiopulmonary exercise test (CPET) is the most comprehensive exercise test currently used. It provides an objective assessment of the patient's training level and an individualised risk profile for complications and guides the perioperative care. This article provides a brief description of the roles of CPET in thoracic surgery. Guidelines recommend it for perioperative assessments because of its prognostic value, its utility in the postoperative period and in pulmonary rehabilitation programmes.
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Fogarty, Colin B., et Dylan S. Small. « Equivalence testing for functional data with an application to comparing pulmonary function devices ». Annals of Applied Statistics 8, no 4 (décembre 2014) : 2002–26. http://dx.doi.org/10.1214/14-aoas763.

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Day, Ronald W. « Acute vasodilator testing following Fontan palliation : an opportunity to guide precision care ? » Cardiology in the Young 30, no 6 (22 mai 2020) : 829–33. http://dx.doi.org/10.1017/s1047951120001110.

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AbstractBackground:Pulmonary vasodilators improve the functional capacity of some patients with pulmonary arterial hypertension. However, pulmonary vasodilators frequently fail to improve unequivocal endpoints of efficacy in patients with lower pulmonary arterial pressures who have been palliated with a Fontan procedure.Objective:Haemodynamic measurements and the results of acute vasodilator testing in a subset of patients were reviewed to determine whether some patients acutely respond more favourably to sildenafil and might be candidates for precision care with a phosphodiesterase V inhibitor long term.Materials and Methods:Heart catheterisation was performed in 11 patients with a Fontan procedure. Haemodynamic measurements were performed before and after treatment with intravenous sildenafil (mean 0.14, range 0.05–0.20 mg/kg). Results (mean ± standard deviation) were compared by paired and unpaired t-tests to identify statistically significant changes.Results:Sildenafil was acutely associated with changes in mean pulmonary arterial pressure, transpulmonary gradient, indexed blood flow, and indexed vascular resistance. Changes in mean pulmonary arterial pressure were greater for patients with a mean pulmonary arterial pressure greater than 14 mmHg compared to patients with a lower mean pulmonary arterial pressure. Changes in transpulmonary gradient were greater for patients with a transpulmonary gradient greater than 5 mmHg compared to patients with a lower transpulmonary gradient.Conclusion:Sildenafil acutely decreases mean pulmonary arterial pressure and transpulmonary gradient and causes greater acute changes in patients with higher mean pulmonary arterial pressures and transpulmonary gradients. Haemodynamic measurements and vasodilator testing might help to guide precision care following Fontan palliation.
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Youssef, Amir A., Shereen A. Machaly, Mohammed E. El-Dosoky et Nermeen M. El-Maghraby. « Respiratory symptoms in rheumatoid arthritis : relation to pulmonary abnormalities detected by high-resolution CT and pulmonary functional testing ». Rheumatology International 32, no 7 (3 avril 2011) : 1985–95. http://dx.doi.org/10.1007/s00296-011-1905-z.

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Raheja, Suraj, Hassan Nemeh, Celeste Williams, Cristina Tita, Yelena Selektor, Themistokles Chamogeorgiakis et David Lanfear. « Pulmonary Function Testing and Outcomes after Left Ventricular Assist Device Implantation ». Heart Surgery Forum 22, no 3 (8 mai 2019) : E202—E206. http://dx.doi.org/10.1532/hsf.2299.

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Background: Pulmonary function testing (PFT) is often done during workup prior to left ventricular assist devices (LVAD), but its utility for predicting outcomes and changes in pulmonary function post-LVAD is not well established. We assessed the association of baseline PFT metrics with outcomes after LVAD, and quantified the changes in PFTs post-LVAD. Methods and results: A retrospective study of 178 patients receiving continuous flow LVADs was conducted. A total of 129 subjects had baseline PFT data and 54 of these had repeat tests after LVAD. We collected PFT data (FEV1, FVC, FEV1/FVC ratios, and DLCO) at baseline and post-LVAD, and tested the association with survival, right heart failure, quality of life (Kansas City Cardiomyopathy Questionnaire [KCCQ]) and functional capacity (six-minute walking distance [6MWD]). Proportional hazards and linear regressions determined relationships between baseline PFT data and survival time and functional outcomes, respectively. Paired t-tests compared pre- and post- LVAD PFT variables. There was no association of baseline PFT parameters with survival time post-LVAD (all P > .2), nor the incidence of perioperative RV failure (all P > .15). There were no significant associations of the baseline PFT metrics with the change in KCCQ or 6MWD. There were statistically significant declines in FEV1, FEV1/FVC ratio, and DLCO after LVAD (P < .05). Conclusion: In this single center study, there was no relationship between baseline PFTs and post-LVAD outcomes, and PFT parameters often worsened after LVAD. Further studies are needed to determine whether PFTs are useful in this setting, and what, if any, impact LVAD therapy has on pulmonary function.
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Thèses sur le sujet "Pulmonary functional testing"

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McHenry, Kristen L. « Pulmonary Function Testing : Know Your Numbers ». Digital Commons @ East Tennessee State University, 2016. https://dc.etsu.edu/etsu-works/2541.

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Soleimani, Vahid. « Remote depth-based photoplethysmography in pulmonary function testing ». Thesis, University of Bristol, 2018. http://hdl.handle.net/1983/f6a6f7b6-943f-43f7-b684-1612161aee1a.

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This thesis introduces several novel, noninvasive lung function assessment approaches in which we incorporate computer vision techniques to remotely compute standard clinical Pulmonary Function Testing (PFT) measures. Using a single depth sensor, a dynamic 3-D model of a subject's chest is reconstructed and used to generate chest volume-time data by estimating the chest volume variation throughout a sequence. Following computation of multiple keypoints and calibration of volume-time data to present real volume of exchanged air, 7 Forced Vital Capacity (FVC) measures and 4 Slow Vital Capacity (SVC) measures are computed. Evaluation on a dataset of 85 patients (529 sequences), attending a respiratory outpatient service for spirometry, shows a high correlation between the proposed depth-based PFT measures and the measures from a spirometer. Trunk motion during PFT affects the accuracy of these results, so the natural reaction of the subject's body to maximal inhalation and exhalation, must be decoupled from the chest-surface breathing motion. We present an automatic, open source data acquisition and calibration pipeline in which two opposing depth sensors are calibrated and used to reconstruct a well-defined dynamic 3-D model of the trunk during PFT performance. Our proposed method is able to reconstruct dynamic 3-D models with accurate temporal frame synchronisation and spatial registration. Then, we propose a whole body depth-based photoplethysmography (dPPG) approach which allows subjects to perform PFT, as in routine spirometry, without restraining their natural trunk reactions. By decoupling the trunk movement and the chest-surface respiratory motion, dPPG obtains more accurate respiratory volume-time data which improves the accuracy of the estimated PFT measures. A dataset spanning 35 subjects (298 sequences) was collected and used to illustrate the superiority of the proposed dPPG method by comparing its measures to those provided by a spirometer and the single Kinect approach. Although dPPG is able to improve the PFT measures accuracy to a significant extent, it is not able to filter complex trunk motions, particularly at the deep forced inhalation-exhalation stage. To effectively correct trunk motion artifacts further, we propose an active trunk shape modelling approach by which the respiratory volume-time data is computed by performing principal component analysis on temporal 3-D geometrical features, extracted from the chest and posterior shape models in R3 space. We validate the method's accuracy at the signal level by computing several comparative metrics between the depth-based and spirometer volume-time data. Evaluating on the dPPG PFT dataset (300 PFT sequences), our trunk shape modelling approach outperforms the single Kinect and dPPG methods.
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Barrau, Nathalie. « 3D MR Spirometry ». Electronic Thesis or Diss., université Paris-Saclay, 2024. http://www.theses.fr/2024UPAST077.

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La ventilation est une fonction complexe, avec des variabilités naturelles intra- et inter-individuelles imprévisibles, parfois inhomogènes dans le volume pulmonaire. La spirométrie standard est l'examen de référence pour évaluer la fonction ventilatoire à partir de courbes débit-volume mesurées à la bouche et en respiration forcée. Cette technique simple et fiable est limité par la nécessaire coopération du patient, ainsi que par la nature globale de sa mesure. Étant donné que la respiration est intrinsèquement un phénomène tridimensionnel et que les maladies pulmonaires sont généralement régionales, la ventilation devrait être sondée localement. Malgré les difficultés inhérentes à l'application de l'IRM au poumon, de récent progrès ont permis de révéler le potentiel de l'IRM fonctionnelle pulmonaire à partir d'acquisitions standards facilement transposables en clinique. Depuis une quinzaine d'années des développements évaluent la ventilation à partir de la variation du signal IRM au cours de la respiration. Ces techniques reposent sur une hypothèse forte de linéarité du signal IRM avec la densité de tissus pulmonaire. Une nouvelle méthode évaluant la ventilation localement et dynamiquement à partir des déformations a été développée : la spirométrie 3D par IRM. A partir d'un cycle respiratoire moyen, le Jacobien des déformations et sa dérivée temporelle permettent d'inférer les courbes débit-volume locales. Cette thèse s'attache à valider la spirométrie 3D par IRM, à l'amener à la recherche clinique, et à approfondir la compréhension de la mécanique ventilatoire. Le caractère multidimensionnel de la spirométrie 3D par IRM intègre la complexité de la fonction respiratoire mais la technique encore neuve doit être développée et éprouvée. Les évolutions méthodologiques entreprises durant cette thèse incluent une reconstruction optimisée de la dynamique pulmonaire, une segmentation précise des structures lobaires, la définition de biomarqueurs quantitatifs, ainsi qu'une normalisation des cartes fonctionnelles pour permettre des comparaison intra- et inter-sujets. Une étude prospective sur 25 volontaires (10 femmes, 45 ± 17 ans) respirant librement a été menée, avec des acquisitions répétées en position allongée. La fiabilité de la technique a été approchée selon deux critères : sa répétabilité et son exactitude. Les mesures de volumes courants locaux intégrés sur le volume pulmonaire correspondent à ce qui peut être mesuré par segmentation des volumes pulmonaires. Une excellente répétabilité globale a été trouvée, avec une variabilité résiduelle induite par celle intrinsèque à la respiration.La sensibilité de la spirométrie 3D par IRM a été d'abord étudiée sur 25 volontaires sains en position allongée sur le dos puis sur le ventre. Les cartes fonctionnelles mettent en évidence un gradient de ventilation vers les régions les plus dépendantes à la gravité, démontrant la sensibilité de la technique à la physiologie. Des atlas fonctionnels ont été établis à partir des cartes individuelles normalisées, révélant les motifs nominaux de la ventilation pulmonaire reproductibles sur la cohorte de volontaire. Les distributions spatiales mettent en évidence l'inhomogénéité de la ventilation en respiration libre.Enfin, la sensibilité de la spirométrie 3D aux pathologies obstructives et restrictives est évaluée à travers plusieurs études de cas de maladies neuromusculaires, COVID-19 longue durée, asthme et bronchopneumopathie chronique obstructive (BPCO). Ces recherches soulignent l'importance de caractériser les modes de respiration avec les contributions des muscles respiratoires. La réversibilité de l'asthme à l'administration d'un bronchodilatateur a été trouvé, avec une augmentation marquée des débits après bronchodilatateurs. Une étude longitudinale sur un cas d'asthme sévère a aussi mis en évidence l'efficacité de la biothérapie pour améliorer la fonction ventilatoire, réduisant le volume résiduel ainsi que l'obstruction
Ventilation is a complex function, with unpredictable natural intra- and inter-individual variabilities, sometimes heterogeneous in lung volume. Standard spirometry is the reference exam to assess the ventilatory function from flow-volume loops measured at the mouth during forced expiration. This simple and reliable technique is limited by the necessary cooperation of the patient, as well as by the global nature of its measurement. Since breathing is inherently a three-dimensional phenomenon and lung diseases are generally regional, ventilation should be probed locally.Despite the inherent difficulties in applying MRI to the lung, recent advancements have revealed the potential of functional pulmonary MRI from easily translatable standard acquisitions in clinical settings. Over the past fifteen years, developments have evaluated ventilation based on MRI signal variation during respiration. These techniques rely on a strong assumption of linearity of the MRI signal with lung tissue density. A new method evaluating ventilation locally and dynamically from deformations has been developed: 3D spirometry by MRI. From an average respiratory cycle, the deformation Jacobian and its temporal derivative allow inference of local flow-volume curves. This thesis aims to validate 3D spirometry by MRI, bring it into clinical research, and deepen the understanding of ventilatory mechanics.The multidimensional nature of 3D spirometry by MRI integrates the complexity of respiratory function, but the new technique must still be developed and tested. Methodological developments undertaken during this thesis include optimized reconstruction of pulmonary dynamics, precise segmentation of lobar structures, definition of quantitative biomarkers, as well as normalization of functional maps to enable intra- and inter-subject comparisons. A prospective study on 25 volunteers (10 females, 45 ± 17 years old) breathing freely was conducted, with repeated acquisitions in the supine position. The reliability of the technique was approached by two criteria: its repeatability and accuracy. Measures of local tidal volumes integrated over the lung volume agreed to the measured lung volumes from segmentation. Excellent overall repeatability was found, with residual variability induced by that intrinsic to respiration.The sensitivity of 3D MR spirometry was first studied in 25 healthy volunteers in lying supine and prone positions. Functional maps highlight a gradient of ventilation toward the more gravity-dependent regions, demonstrating the sensitivity of the technique to physiology. Functional atlases were established from normalized individual maps, revealing reproducible nominal patterns of pulmonary ventilation across the volunteer cohort. Spatial distributions highlight the heterogeneity of ventilation during free breathing.Finally, the sensitivity of 3D MR spirometry to obstructive and restrictive pathologies is evaluated through several case studies of neuromuscular diseases, long COVID-19, asthma, and chronic obstructive pulmonary disease (COPD). These studies emphasize the importance of characterizing breathing patterns with contributions from respiratory muscles. Reversibility of asthma with bronchodilator administration was found, with a marked increase in flow rates after bronchodilators. A longitudinal study on a case of severe asthma also demonstrated the effectiveness of biotherapy in improving ventilatory function and reducing residual volume and obstruction
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Morgan, Erin, et Janice Lazear. « Implementation of Pulmonary Function Testing in Rural Primary Care ». Digital Commons @ East Tennessee State University, 2019. https://dc.etsu.edu/etsu-works/7080.

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Pulmonary function testing (PFT) is recommended by guidelines for the diagnosis of chronic obstructive pulmonary disease and the diagnosis and monitoring of asthma. Portable in-office tests offer rural patients and providers information previously more difficult to obtain because of hospital closures, transportation barriers, and cost. This article describes the successful implementation and measurement of in-office PFT in 3 rural primary care offices. Providers were more likely to order a PFT for patients with asthma (33%) than a patient with chronic obstructive pulmonary disease (9.7%). Recommendations include increased staff involvement and repeat education midimplementation.
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Ghali, Maged. « Implications of preoperative pulmonary function testing for post liver transplant outcomes ». Thesis, McGill University, 2008. http://digitool.Library.McGill.CA:80/R/?func=dbin-jump-full&object_id=18802.

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ABSTRACT Pulmonary complications are common post-transplant and may lead to increased mortality. Pulmonary function tests (PFTs) are routinely obtained preoperatively, but their usefulness in liver transplantation is unknown. The objective of this study was to assess the impact of preoperative PFTs on postoperative pulmonary complications (PPCs), ICU stay, and death post-liver transplant. This single site historical cohort study encompassed all 531 liver transplants performed in 462 patients at the Royal Victoria Hospital through June 30, 2006. Outcomes included death, PPCs, and length of intubation and ICU stay. Independent variables including PFTs, age, gender, race, smoking history, etiology of liver disease, MELD score, and ischemia time were used in logistic regression and Cox proportional hazards models to assess their impact on the outcomes listed above. 205 patients had complete PFT data. Decreased total lung capacity (TLC) was a predictor of increased length of ICU stay, duration of intubation, and mortality. A 10% decrease in TLC increased the mortality risk by 43%. Increased residual volume (RV), cold ischemia time, and age were predictors of mortality. Predictors of prolonged ICU stay or intubation were TLC, MELD score, male gender and cold ischemia time. PFTs were not significant predictors of PPCs. PFTs do not predict pulmonary complications but predict length of ICU stay and intubation, as well as mortality. PFTs may reflect the severity of underlying liver disease as well as intrinsic lung disease.
RÉSUMÉ Les complications respiratoires sont fréquentes après les greffes et peuvent amener un taux accru de mortalité. Les tests de fonction pulmonaire sont maintenant obtenus régulièrement en phase pré-opératoire. Cependant, leur pertinence dans les cas de greffes hépatique est inconnue. Le but de cette étude est d'évaluer la capacité de prédiction des tests de fonction pulmonaire pré-opératoires sur les complications post-opératoires, la durée de séjour aux soins intensifs et les risques de mortalité post-greffe hépatique. Cette étude rétrospective fut menée à un site de référence pour les greffes hépatiques, soit l'Hôpital Royal Victoria. Nous avons révisé toutes les opérations (531) qui furent effectués chez 462 patients jusqu'au 30 juin 2006. Nous avons considéré les décès, les complications pulmonaires, ainsi que la durée d'intubation et la durée de séjour aux soins intensifs en tant que variables dépendants. Les facteurs prédictives étaient des tests de fonction pulmonaire, l'âge, le sexe, l'origine ethnique, l'histoire de tabagisme, le type de maladie hépatique sous-jacent, le score MELD et le temps ischémique de la greffe. Nous avons utilisé des modèles de régression logistique et de Cox afin d'évaluer la capacité prédictive indépendante des tests de fonction pulmonaire ainsi que des autres variables. 205 patients avaient des données complètes de leurs tests de fonction respiratoire en pré-opératoire. Une réduction dans la capacité pulmonaire totale étant associée de façon significative à la durée de séjour aux soins intensifs, ainsi qu'une durée accrue d'intubation et à un taux accru de mortalité. Ainsi, une diminution de 10% dans la capacité pulmonaire totale respiratoire en pré-opératoire était associée de façon indépendante à une augmentation de 43% du risque de mortalité. Une augmentation du volume résiduel, ainsi qu'une augmentation du temps ischémique et
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Shawcross, Anna. « Infant multiple breath washout using a novel open-closed circuit system ». Thesis, University of Manchester, 2018. https://www.research.manchester.ac.uk/portal/en/theses/infant-multiple-breath-washout-using-a-novel-openclosed-circuit-system(06f61a8a-f731-4a60-b0fe-ad330582d7bd).html.

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Background: Lung clearance index (LCI), obtained by multiple breath washout testing (MBW), is a sensitive measure of lung disease in infants. It has been identified as a particularly suitable endpoint for clinical trials in cystic fibrosis (CF), but has potential applications in many other conditions. However, MBW in infants presents a number of technical challenges. Conventional MBW is based on simultaneous measurement of flow and gas. These two signals are then aligned and combined to derive expired gas volumes and measures of ventilation inhomogeneity: this process becomes increasingly vulnerable to errors in gas signal alignment at rapid respiratory rates. At present, no existing system for infant MBW meets all the criteria set out in international guidelines, and there is no simple method of assessing lung function outside research laboratories in this population. This thesis describes an alternative method of performing MBW in infants. In this method, expired gas is collected and analysed to derive functional residual capacity (FRC) and LCI. There is no need to simultaneously measure flow, and therefore no need for the complicated step of integrating flow and gas signals. Dead space is also significantly reduced by removing the flowmeter. Methods: In the first phase of testing, an existing lung model was modified to generate realistic infant breathing parameters with high accuracy. The prototype system was modified to improve accuracy and subsequently tested at FRC of 100-250mls with respiratory rates of 20-60min-1. In the second phase, testing proceeded to an in vivo pilot study of the novel method in children with cystic fibrosis and healthy controls. Practical applicability of the system was determined by the number of successful duplicate tests, and within-subject repeatability. Comparison was made with LCI measurements obtained using a respiratory mass spectrometer, currently considered the gold standard for infant LCI. Results: In a total of 103 tests performed in the lung model, overall mean error (standard deviation) of FRC measurement was -1.0(3.3)%, with 90% of tests falling within +/-5%. 13 patients were excluded from the clinical study due to being unsedated or inadequately sedated and therefore failing to tolerate the test. A total of 25 patients (7 children with CF, 18 healthy control children) were deemed to be adequately sedated at the start of the test, of these 20 patients (7 with CF) successfully underwent duplicate testing (80% success rate). Mean FRC for healthy controls was 19.5ml/kg, and mean LCI 6.45. For children with CF, mean FRC was 21.8ml/kg and mean LCI 6.98. Mean within-subject coefficient of variation for FRC was 7.18% and for LCI 5.94%. Of 4 infants assessed with both the novel method and the respiratory mass spectrometer, there was good correlation in FRC measurement (mean difference -8.1%). Comparison of LCI with the mass spectrometer was affected by technical difficulties with the test; in those patients who underwent technically adequate tests with both methods, mean difference in LCI between the two methods was 1.65%. Discussion: FRC measurement using the novel method has superior accuracy in vitro than previously described systems. Data from the pilot study suggest that this is a feasible and reproducible method of performing LCI in infants and young children, as long as they are adequately sedated. Results in both children with CF and controls fall within the expected range, and well within accuracy limits set by international guidelines. However, the system and testing protocol could be further improved to reduce the number of technically inadequate tests having to be excluded. This could provide a more accessible alternative to previously described systems for infant MBW.
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Cullimore, Annemarie. « Inflammatory airway disease in horses : The association between bronchoalveolar lavage cytology and pulmonary function testing ». Thesis, Cullimore, Annemarie (2015) Inflammatory airway disease in horses : The association between bronchoalveolar lavage cytology and pulmonary function testing. Masters by Research thesis, Murdoch University, 2015. https://researchrepository.murdoch.edu.au/id/eprint/30299/.

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Inflammatory airway disease (IAD) describes a condition of non-septic inflammation of the lower airways in horses. The disease occurs principally in adult horses and has an apparent worldwide distribution. The most common clinical signs of IAD include poor athletic performance, cough, and/or increased tracheobronchial secretions. Inconsistencies in disease definition, sampling methods and laboratory techniques have limited comparisons between studies. Essential criteria for diagnosis of IAD, as stated by the 2007 ACVIM consensus statement, include documentation of non-septic inflammation or pulmonary dysfunction based on evidence of lower airway obstruction, airway hyperresponsiveness, or impaired blood gas exchange at rest or during exercise. A definitive diagnosis is currently based on bronchoalveolar lavage fluid (BALF) cytology and/or pulmonary function testing (PFT). The correlation between BALF cytology and pulmonary function testing (PFT) has been poorly defined. The primary aim of this study was to characterise the relationship between BALF cytology and PFT with histamine bronchoprovocation methods in a population of sedentary asymptomatic horses. The principal hypothesis was that a strong association exists between these two diagnostic methods. On the basis of BALF cytology the majority of horses in this study had lower airway inflammation as defined by published criteria. The study thus highlights that normal values for cell proportions in BALF might vary between populations of horses. Despite an obvious overlap between inflammatory BALF cytological profiles and airway hyperresponsiveness, no statistical association between these two diagnostic methods was found in this population of horses. The secondary aim was to assess the reliability of the Open Pleth™ PFT system Acceptable reliability {ICC: 0.655 (95% CI: 0.098, 0.952; significance: 0.011)}) was demonstrated using the Flowmetrics Plethysmography™ system with histamine bronchoprovocation. In conclusion, airway inflammation and airway hyperreactivity are loosely related to each other in this population of horses. The presence of inflammatory cells does not necessarily predict airway hyperresponsiveness on the basis of histamine bronchoprovocation. Likewise, airway hyperresponsiveness can occur in the absence of a BALF inflammatory profile. Further investigation of other potential factors such as inherited abnormalities of smooth muscle contractility, airway wall remodelling, autonomic dysfunction, and the presence of inflammatory cell mediators in bronchoalveolar lavage fluid are warranted.
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Steffen, Priscilla. « Clinical Practice Guideline Implementation for Alpha-1 Antitrypsin Deficiency Testing : Evaluation of an Innovative Method ». Diss., The University of Arizona, 2010. http://hdl.handle.net/10150/194842.

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Purpose/Aims: The American Thoracic Society (ATS) published recommendations for alpha-1 antitrypsin deficiency (AATD) testing in 2003. This descriptive project evaluates the outcomes of ATS AATD guideline use in the setting of the pulmonary function testing (PFT) lab.The specific aims met by this descriptive project describe the prevalence of AATD cases and carriers in the sample, examine to what degree the established clinical guideline promoted accurate patient selection for the alpha-1 test in the sample, and aimed to determine whether alpha-1 antitrypsin blood levels are reduced in current smokers compared to former or never smokers.Background: Alpha-1 antitrypsin prevents lung tissue breakdown by attenuating excess elastase released from neutrophils during the inflammatory response. Smoking impairs alpha-1 antitrypsin protection at the site of lung inflammation promoting emphysema development. In the case of genetic mutation, protective alpha-1 antitrypsin levels are reduced, causing emphysema even in non-smokers. Significantly reduced protective levels of alpha-1 antitrypsin increase the odds for morbidity and early mortality from emphysema. The literature provides support for targeted testing in the population most affected.Sample/Methods: The sample population included adults 21 through 79 years completing pulmonary function testing over 18 months in a metropolitan pulmonary medicine practice and was retrospectively reviewed.Of the 521 in the sample, 190 were tested for AATD, and 24 were found to carry an abnormal genotype. However, using Table 11 from the ATS CPG failed to provide structured, consistent guidance in selecting patients for AATD testing. Still, the prevalence of the abnormal genotypes MS, MZ, SZ, and ZZ was increased in this pulmonary population compared to the published estimated prevalence for the general population.A structured decision-tree, developed from the original guideline for diagnostic testing, may provide superior guidance for AATD test patient selection in this setting. Increased case finding by targeted testing of patients in the setting of the pulmonary function lab can serve to integrate this clinical practice guideline in a consistent streamlined fashion.In this sample, no difference between AAT blood levels among ever, never, and current tobacco smokers was detected. A more powerful sample is needed.
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Maduko, Elizabeth. « Development and testing of a neuro-fuzzy classification system for IOS data in asthmatic children ». To access this resource online via ProQuest Dissertations and Theses @ UTEP, 2007. http://0-proquest.umi.com.lib.utep.edu/login?COPT=REJTPTU0YmImSU5UPTAmVkVSPTI=&clientId=2515.

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Ambrozin, Alexandre Ricardo Pepe [UNESP]. « Complicações pós-operatórias em cirurgia torácica relacionadas aos índices e testes preditores de risco cirúrgico pré-operatórios ». Universidade Estadual Paulista (UNESP), 2009. http://hdl.handle.net/11449/86296.

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Made available in DSpace on 2014-06-11T19:22:12Z (GMT). No. of bitstreams: 0 Previous issue date: 2009-12-15Bitstream added on 2014-06-13T19:48:21Z : No. of bitstreams: 1 ambrozin_arp_dr_botfm.pdf: 169682 bytes, checksum: e35521aad39da34ec6c55a5da6cd12ad (MD5)
Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)
Algumas variáveis propostas para predizer o risco de complicação pósoperatória (CPO) são a altura no teste da escada (TE) e a distância do teste de caminhada de seis minutos (TC6) e acreditamos que o tempo no teste da escada (tTE) também pode ser utilizado para este fim. Além disso, são utilizados a prova de função pulmonar e os índices pré-operatórios. Objetivo: Determinar se os índices de Torrington e Henderson, American Society of Anesthesiologists, Goldman, Detsky e Charlson, a variável VEF1 da espirometria e as variáveis obtidas nos testes de esforço (TC6 e TE) podem ser preditivos das complicações pós-toracotomia e qual deles seria o melhor preditor dessas complicações. Método: Foram avaliados pacientes com indicação de toracotomia para ressecção pulmonar ou não, maiores de 18 anos. As comorbidades foram obtidas e traçados os índices de Comorbidade de Charlson, de risco de Torrington e Henderson, de Goldman, de Detsky e o ASA. A espirometria foi realizada de acordo com a ATS, em espirômetro Medgraphics Pulmonary Function System 1070. O TC6 foi realizado segundo os critérios da ATS e a distância prevista calculada. O TE foi realizado numa escada à sombra, composta por seis lances, num total de 12,16m de altura. O tTE em segundos percorrido na subida da altura total foi obtido e a partir deste a Potência (P) foi calculada utilizando a fórmula clássica. Também foi estimado o VO2 a partir do tTE (VO2 t) e da P (VO2 P). No intra-operatório foram registradas as complicações e o tempo cirúrgico. E no pós-operatório foram registradas as CPOs. Para análise estatística os pacientes foram divididos em grupos sem e com CPO. Foi aplicado o teste de acurácia para obtenção dos valores preditivos para o TC6 e para o tTE, a curva ROC e dessa o ponto de corte. As variáveis foram testadas para uma possível associação com as CPO pelo teste t de...
Some varieties purposed to predict the postoperative complication (POC) risk are the height in the stair-climbing test (SCT) and the distance in the six minute walk test (6MWT), we also believe that the time on the stair-climbing test can also be used for this purpose. Besides, the pulmonary function test and the preoperative index are also used. Objectives: We aim to determine if the Charlson, Torrington and Henderson, Goldman, Detsky and American Society of Anesthesiologists indexes, the variable FEV1 obtained on the Spirometry and on the Cardiopulmonary Exercise Testing (6MWT, SCT) can be predictive of the complication after thoracic surgery and which one of them would be the best. Method: Patients with indication to thoracic surgery, for resection or not, and older than 18 years old were evaluated. The comorbidities were obtained and the Comorbidity Charlson, Torrington and Henderson risk, Goldman, the Detsky and ASA indexes were calculated. The spirometry was performed according to ATS in Medgraphics Pulmonary Function System 1070. The 6MWT was performed according to the ATS criteria and the predicted distance was calculated. The SCT was performed indoor, on six flights of stairs, which results as a 12,16m climb. The time on the SCT was obtained after finished the stair height total in seconds and the Power (P) was calculated using the class formula. The maximum oxygen uptake (VO2) was estimated from the time of SCT (VO2 t) and the P (VO2 P). In the intraoperative was registered the complication and the surgery time. And in the postoperative was registered the POC. In the statistics analysis, the patients were divided in groups with and without POC. It was applied the accuracy test for the distance 6MWT and for the time in the SCT. We have found the cutoff from the ROC curve. The correlation between the variables and POC were tested using the t test for independent population ... (Complete abstract click electronic access below)
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Livres sur le sujet "Pulmonary functional testing"

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Kaminsky, David A., et Charles G. Irvin, dir. Pulmonary Function Testing. Cham : Springer International Publishing, 2018. http://dx.doi.org/10.1007/978-3-319-94159-2.

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Cherniack, Reuben M. Pulmonary function testing. 2e éd. Philadelphia : Saunders, 1992.

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Cherniack, Reuben Mitchell. Pulmonary function testing. 2e éd. Philadelphia : W. B. Saunders, 1992.

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L, Chupp Geoffrey, dir. Pulmonary function testing. Philadelphia : Saunders, 2001.

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A, Mahler Donald, dir. Pulmonary function testing. Philadelphia : W. B. Saunders, 1989.

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Chupp, Geoffrey L. Pulmonary function testing. Philadelphia, PA : W.B. Saunders Co., 2001.

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Jürg, Hammer, et Eber Ernst, dir. Paediatric pulmonary function testing. Basel : Karger, 2005.

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E, Hansen James. Pulmonary function testing & interpretation. New Delhi : Jaypee Brothers Medical Publishers, 2011.

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Manual of pulmonary function testing. 4e éd. St. Louis : Mosby, 1986.

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Ruppel, Gregg. Manual of pulmonary function testing. 7e éd. St. Louis, Mo : Mosby, 1998.

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Chapitres de livres sur le sujet "Pulmonary functional testing"

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Gustafsson, P. M., et H. Ljungberg. « Measurement of Functional Residual Capacity and Ventilation Inhomogeneity by Gas Dilution Techniques ». Dans Paediatric Pulmonary Function Testing, 54–65. Basel : KARGER, 2005. http://dx.doi.org/10.1159/000083521.

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Thiboutot, Jeff, Bruce R. Thompson et Robert H. Brown. « Introduction to the Structure and Function of the Lung ». Dans Pulmonary Function Testing, 1–13. Cham : Springer International Publishing, 2018. http://dx.doi.org/10.1007/978-3-319-94159-2_1.

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Lee, Annemarie L., Theresa Harvey-Dunstan, Sally Singh et Anne E. Holland. « Field Exercise Testing : 6-Minute Walk and Shuttle Walk Tests ». Dans Pulmonary Function Testing, 197–217. Cham : Springer International Publishing, 2018. http://dx.doi.org/10.1007/978-3-319-94159-2_10.

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Neder, J. Alberto, Andrew R. Tomlinson, Tony G. Babb et Denis E. O’Donnell. « Integrating the Whole : Cardiopulmonary Exercise Testing ». Dans Pulmonary Function Testing, 219–48. Cham : Springer International Publishing, 2018. http://dx.doi.org/10.1007/978-3-319-94159-2_11.

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Hall, Graham L., et Daniel J. Weiner. « Special Considerations for Pediatric Patients ». Dans Pulmonary Function Testing, 249–69. Cham : Springer International Publishing, 2018. http://dx.doi.org/10.1007/978-3-319-94159-2_12.

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Culver, Bruce H., et Sanja Stanojevic. « Reference Equations for Pulmonary Function Tests ». Dans Pulmonary Function Testing, 271–89. Cham : Springer International Publishing, 2018. http://dx.doi.org/10.1007/978-3-319-94159-2_13.

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Blonshine, Susan, Jeffrey Haynes et Katrina Hynes. « Management of and Quality Control in the Pulmonary Function Laboratory ». Dans Pulmonary Function Testing, 291–311. Cham : Springer International Publishing, 2018. http://dx.doi.org/10.1007/978-3-319-94159-2_14.

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Wu, Tianshi David, Meredith C. McCormack et Wayne Mitzner. « The History of Pulmonary Function Testing ». Dans Pulmonary Function Testing, 15–42. Cham : Springer International Publishing, 2018. http://dx.doi.org/10.1007/978-3-319-94159-2_2.

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Irvin, Charles G., et Jack Wanger. « Breathing In : The Determinants of Lung Volume ». Dans Pulmonary Function Testing, 43–60. Cham : Springer International Publishing, 2018. http://dx.doi.org/10.1007/978-3-319-94159-2_3.

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King, Gregory, et Sylvia Verbanck. « Distribution of Air : Ventilation Distribution and Heterogeneity ». Dans Pulmonary Function Testing, 61–76. Cham : Springer International Publishing, 2018. http://dx.doi.org/10.1007/978-3-319-94159-2_4.

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Actes de conférences sur le sujet "Pulmonary functional testing"

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Kronberger, Christina, Roya Mousavi, Begüm Öztürk, Robin Willixhofer, Brigitte Litschauer et Roza Badr Eslam. « Functional capacity testing in patients with pulmonary hypertension (PH) using the one-minute sit-to-stand test (1-min STST) ». Dans ERS International Congress 2023 abstracts. European Respiratory Society, 2023. http://dx.doi.org/10.1183/13993003.congress-2023.oa4220.

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DeGan, Jonathan, Jeffrey Kennington, Kameswararao Anupindi, Dinesh Shetty, Jun Chen, Mark Rodefeld et Steven Frankel. « Modeling of Patient-Specific Fontan Physiology From MRI Images for CFD Testing of a Cavopulmonary Assist Device ». Dans ASME 2011 Summer Bioengineering Conference. American Society of Mechanical Engineers, 2011. http://dx.doi.org/10.1115/sbc2011-53339.

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Single ventricle heart disease is a congenital condition characterized by the inoperability of one ventricle of an infant’s heart. Those suffering from this condition face a series of palliative surgeries called the Fontan procedure, which bypasses the non-functional ventricle by creating a total cavopulmonary connection, or TCPC. This TCPC forms from the anastomosis of the superior and inferior vena cavae (SVC, IVC) to the left and right pulmonary arteries (LPA, RPA), thus allowing systemic blood flow to bypass the heart and flow passively to the lungs. The Fontan procedure creates this junction with three surgeries separated by months or years.
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Shandurkova, Silvia, Martin Stoychevski et Stefaniya Belomazheva-Dimitrova. « IMPROVING AEROBIC CAPACITY AND SPINE FLEXIBILITY THROUGH ADAPTED SWIMMING EXERCISES FOR PUPILS IN PRIMARY SCHOOL ». Dans INTERNATIONAL SCIENTIFIC CONGRESS “APPLIED SPORTS SCIENCES”. Scientific Publishing House NSA Press, 2022. http://dx.doi.org/10.37393/icass2022/153.

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ABSTRACT Proper motor development in primary school children is the main goal of physical education. The most common medical problems for pupils are spinal deformities. Our focus was on correcting different types of spinal deformities through an adapted swimming methodology. This paper discusses the use of specific swimming exercises to improve the aerobic capacity and spinal flexibility in order to acquire good body posture and to prevent further deformities. The contingent of the study were 21 boys and 19 girls, ages 7 - 10, with a medical diagnosis of spinal deformities, which were included in experimental and control groups, doing adapted swimming exercises from our experimental methodology and routine swimming exercises. The research methods were functional tests for assessing the aerobic capacity – spirometry, Hirz in inhale and exhale and spinal flexibility tests – bending left, right, and forwards. They were conducted in March and September 2020. Descriptive statistics, hypothesis testing, and correlation analysis were used for data analysis. The research results revealed that the pupils improved their chest mobility, pulmonary function, aerobic capacity, and spine flexibility. Statistically significant differences appeared between the groups in favor of the experimental methodology. The adapted swimming exercises should be used in future practice.
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Guy, Harold J. B., G. K. Prisk et J. B. West. « Testing Pulmonary Function in SpaceLab ». Dans International Conference On Environmental Systems. 400 Commonwealth Drive, Warrendale, PA, United States : SAE International, 1991. http://dx.doi.org/10.4271/911565.

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Stalica, Jennifer, Leway Chen, Patricia Sime et R. Matthew Kottmann. « Pulmonary Function Testing And Heart Transplantation ». Dans American Thoracic Society 2011 International Conference, May 13-18, 2011 • Denver Colorado. American Thoracic Society, 2011. http://dx.doi.org/10.1164/ajrccm-conference.2011.183.1_meetingabstracts.a4659.

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Pittman, Jessica E., Robin C. Johnson et Stephanie D. Davis. « Bronchodilator Responsiveness By Infant Pulmonary Function Testing ». Dans American Thoracic Society 2010 International Conference, May 14-19, 2010 • New Orleans. American Thoracic Society, 2010. http://dx.doi.org/10.1164/ajrccm-conference.2010.181.1_meetingabstracts.a3916.

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Ahmad, Jahanzeb, Jiuai Sun, Lyndon Smith, Melvyn Smith, John Henderson et Anirban Majumdar. « Novel Photometric Stereo Based Pulmonary Function Testing ». Dans 3rd International Conference on 3D Body Scanning Technologies, Lugano, Switzerland, 16-17 October 2012. Ascona, Switzerland : Hometrica Consulting - Dr. Nicola D'Apuzzo, 2012. http://dx.doi.org/10.15221/12.091.

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Sidhu, Baljinder, Nastran Hashemi, Ali Rashidian, Sharad Sharma, Narinder Gill, Paul Mills et Vijay Balasubramanian. « Utility Of Pulmonary Function Testing In Detection Of Pulmonary Arterial Hypertension ». Dans American Thoracic Society 2012 International Conference, May 18-23, 2012 • San Francisco, California. American Thoracic Society, 2012. http://dx.doi.org/10.1164/ajrccm-conference.2012.185.1_meetingabstracts.a1875.

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Soleimani, Vahid, Majid Mirmehdi, Dima Damen, Sion Hannuna, Massimo Camplani, Jason Viner et James Dodd. « Remote pulmonary function testing using a depth sensor ». Dans 2015 IEEE Biomedical Circuits and Systems Conference (BioCAS). IEEE, 2015. http://dx.doi.org/10.1109/biocas.2015.7348445.

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Tsirilakis, K., et E. Sather. « Pulmonary Function Testing in Vaping Associated Lung Injury ». Dans American Thoracic Society 2020 International Conference, May 15-20, 2020 - Philadelphia, PA. American Thoracic Society, 2020. http://dx.doi.org/10.1164/ajrccm-conference.2020.201.1_meetingabstracts.a7684.

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