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Littérature scientifique sur le sujet « Protesi totali »

Auteur : Grafiati
Publié le 9 mars 2023
Mis à jour le 10 mars 2023

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Articles de revues sur le sujet "Protesi totali"

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Bistolfi, Alessandro, Ferdinando Tosto, Francesco Lagalla, Luigi Sabatini, Eugenio Graziano, Elvio Novarese et Alessandro Massè. « Protesi totali di ginocchio vincolate ». LO SCALPELLO-OTODI Educational 31, no 2 (juillet 2017) : 168–72. http://dx.doi.org/10.1007/s11639-017-0207-y.

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Mansat, P., et N. Bonnevialle. « Revisione delle protesi totali del gomito ». EMC - Tecniche Chirurgiche - Chirurgia Ortopedica 11, no 1 (2015) : 1–12. http://dx.doi.org/10.1016/s2211-0801(16)30002-4.

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Romagnoli, S., et F. Verde. « L’allineamento coronale nelle protesi totali di ginocchio ». LO SCALPELLO-OTODI Educational 27, no 3 (28 novembre 2013) : 126–31. http://dx.doi.org/10.1007/s11639-013-0036-6.

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Ursino, N., A. Dagnino, P. Giacomello et C. E. Fiorentini. « Il bilancio legamentoso nelle protesi totali di ginocchio ». LO SCALPELLO-OTODI Educational 27, no 3 (14 novembre 2013) : 106–10. http://dx.doi.org/10.1007/s11639-013-0043-7.

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Henry, J., et M. H. Fessy. « Revisione con protesi non cementata nelle mobilizzazioni asettiche del cotiloide nelle protesi totali d’anca ». EMC - Tecniche Chirurgiche - Chirurgia Ortopedica 7, no 2 (2011) : 1–10. http://dx.doi.org/10.1016/s2211-0801(11)70340-5.

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Bizot, P. « Tecnica di impianto delle protesi totali d'anca non cementate ». EMC - Tecniche Chirurgiche - Chirurgia Ortopedica 15, no 1 (janvier 2019) : 1–12. http://dx.doi.org/10.1016/s2211-0801(20)30003-0.

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Viganò, R., A. Fanelli, D. Ghisi, G. Danelli et S. E. De Martinis. « Il controllo del dolore nelle protesi totali di ginocchio ». LO SCALPELLO-OTODI Educational 27, no 3 (22 novembre 2013) : 147–52. http://dx.doi.org/10.1007/s11639-013-0033-9.

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Randelli, P., D. Cucchi, A. D’Anna, A. Menon, S. Grossi, S. Carminati, F. Randelli et P. Cabitza. « Il planning pre-operatorio nelle protesi totali di ginocchio ». LO SCALPELLO-OTODI Educational 27, no 3 (28 novembre 2013) : 82–87. http://dx.doi.org/10.1007/s11639-013-0045-5.

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Martinot, P., E. Disegni, A. Blairon, S. Putman, J. Girard et H. Migaud. « Trattamento chirurgico delle lussazioni delle protesi totali d'anca : diagnosi e trattamento ». EMC - Tecniche Chirurgiche - Chirurgia Ortopedica 15, no 2 (février 2019) : 1–14. http://dx.doi.org/10.1016/s2211-0801(20)30006-6.

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Adravanti, P., et A. Ampollini. « Il bilanciamento degli spazi e il ripristino della rima articolare nelle protesi totali di ginocchio ». LO SCALPELLO-OTODI Educational 27, no 3 (décembre 2013) : 111–15. http://dx.doi.org/10.1007/s11639-013-0037-5.

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Thèses sur le sujet "Protesi totali"

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BIGONI, MARCO. « Risultati clinici preliminari nela valutazione della massa ossea periprotesica in pazienti portatori di protesi totali di ginocchio ». Bachelor's thesis, Università degli studi di Milano-Bicocca, 1996. http://hdl.handle.net/10281/38076.

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De, Scrilli Maria. « Analisi videofluoroscopica sul posizionamento delle componenti protesiche nella sostituzione totale di ginocchio : confronto fra due diversi sistemi innovativi ». Bachelor's thesis, Alma Mater Studiorum - Università di Bologna, 2012. http://amslaurea.unibo.it/4254/.

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Marchezan, Walter. « Estudo comparativo de quatro materiais e de duas técnicas, simples e dupla, para moldagens funcionais em prótese total ». reponame:Biblioteca Digital de Teses e Dissertações da UFRGS, 2004. http://hdl.handle.net/10183/6765.

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Este trabalho avaliou comparativamente, em laboratório, a fidelidade dimensional de quatro materiais de moldagem usados nas moldagens finais em prótese total, um hidrocolóide irreversível (Hidrogum), um poliéter (Impregum) e dois silicones de adição (Honigum e Extrude), bem como a técnica de dupla moldagem, com ou sem alívio, usando o material Extrude de consistências média e leve. Para isto foi usado como corpo de prova um modelo metálico que simula um maxilar edêntulo, onde foram colocados quatro postes em forma do pirâmide, três truncadas, colocadas na crista do rebordo para medições horizontais, e uma inteira, que servia de referência para uma medição vertical. Com cada material ou técnica foram feitos dez moldes do modelo padrão, que foram vazados com gesso tipo IV. Os sessenta modelos obtidos, bem como o modelo-padrão, foram submetidos às medições das distâncias entre as referências situadas nas pirâmides, três medidas no sentido horizontal e uma no sentido vertical. Isto foi feito numa máquina para medição por coordenadas (tridimensionai), BRT-M507 fabricada pela Mitutoyo, com software Cosmos/Geopak-Win. Os resultados foram submetidos à analise de variância e testes complementares (Post Hoc Tests, de Duncan). A análise dos resultados mostra que quase todas as medidas no plano horizontal foram menores nas réplicas que no padrão, e que na medida vertical a discrepância entre os resultados foi maior, sendo umas medidas maiores e outras menores que no padrão. Estatisticamente, apenas numa das três distâncias avaliadas, Dist. 2, não houve diferença significativa entre os materiais. Concluiu-se que, com exceção do material Extrude em moldagem simples, os silicones e o poliéter tiveram desempenho semelhante, e que o hidrocolóide irreversível evidenciou os piores resultados. Outra conclusão foi que as duas técnicas de dupla moldagem usando materiais de consistências diferentes mostraram resultados semelhantes ao Honigum e Impregum, sendo mais precisas que estes na reprodução da altura, medida relacionada com a moldagem da zona de postdamming no paciente edêntulo.
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Cardoso, Luiz Antonio Morais 1963. « Programação de articuladores em protese total : comparação entre metodos ». [s.n.], 1997. http://repositorio.unicamp.br/jspui/handle/REPOSIP/289450.

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Orientador: Jose Roberto Lovadino
Tese (doutorado) - Universidade Estadual de Campinas, Faculdade de Odontologia de Piracicaba
Made available in DSpace on 2018-07-23T03:09:08Z (GMT). No. of bitstreams: 1 Cardoso_LuizAntonioMorais_D.pdf: 1865461 bytes, checksum: eae73caa17a06a50397f7619a4458242 (MD5) Previous issue date: 1997
Resumo: Neste estudo foram considerados dois valores de grande interesse protético: inclinação da trajetória condílica ântero-posterior (guia condilar) e ângulo de Bennett. Essas duas grandezas serviram para referência de comparação entre dois métodos de programação de articuladores empregados na confecção de próteses totais. O primeiro método foi o chamado desgaste de Paterson que utiliza arcos de orientação com mistura abrasiva, que atritados pelo próprio paciente, conforma individualmente cada conjunto, que por sua vez, serve para programar o articulador. O segundo método, chamado técnica de Nóbilo, emprega o registro intra oral modificado, permitindo que as posições de interesse para a programação do articulador sejam definidas e tranferidas com o auxílio de moldagens vestibulares das posturas. Os métodos foram aplicados em 27 pacientes desdentados totais. Para a inclinação da guia condilar, o método de Paterson obeve média de 26,10 graus e o de Nóbilo 30,87 graus. Para o ângulo de Bennnett, o método de Paterson conseguiu 13,14 graus e o de Nóbilo 16,34 graus. Para ambos os valores protéticos a análise de variância considerou haver diferença entre os resultados obtidos pelos métodos. No entanto, em relação ao lado das articulações, nenhum método detectou diferença
Abstract: In this study were considerate two values with big prosthetic interest: anterior-posterior trajectory inclination of condyle and Bennett angle. These two greatness were useful for reference to compare two methods of articulators programation employed in dentures construclion. The first method was called Paterson abrasion that wich utilize orientation arcs with abrasive misture, frictioned for the own patient conform individualy each conjunct; that which in this way serve to articulator shedule. The second method, called Nobilo's technique used the intra-oral register modifyed, allowing to be defined to the articulator sheduling to be able to be defined and transfered with the vestibular posture impression. The methods were apliyed in 27 patients. To the inclination of condylar guide, the Paterson method got 26.10 grades and Nobilo's one got 30.87 grades. To the Bennett angle, Paterson method got 13.14 grades and Nobilo's one got 16.34 grades. To both prosthetic values, the variance analysis considered to the difference between the results got for the two methods. Never the lless in articulations side relation, no one method detected differences
Doutorado
Protese
Doutor em Clínica Odontológica
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Cottam-Howarth, Barry. « Towards PNA directed chemical total protein synthesis ». Thesis, University of Leeds, 2007. http://etheses.whiterose.ac.uk/21098/.

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This thesis is concerned wi.th the development of a novel methodology for the chemical synthesis of proteins. The methodology is expected to overcome limitations of current techniques for chemical synthesis of proteins that restrict the size of the target molecule to less than 150 amino acids. It is intended that the use of a DNA analogue, PNA, as a directing group will allow different short polypeptides to self-assemble into a desired target protein. The first chapter is an overview of literature concerning templated synthesis and the applications of PNA. Examples of simple mctal-templated synthesis are discussed however there is a particular focus on the work of David Liu and his DNA-templated synthesis. The uses of PNA in a number of diverse applications are presented along with brief comparative descriptions of PNA and DNA. A brief discussion of current methodologies for protein synthesis is then used to set the context for the project aims and a description of the proposed methodology. The second chapter details the effort made in modifying literature procedures to successfully develop the robust and reproduCible cqemistry required for multi-gram synthesis ofPNA monomers. The third chapter briefly discusses the computer-aided design of a pair of linker molecules that act as a bridge between polypeptides and their PNA directing groups. The challenging synthesis of these linker molecules is detailed and synthetic routes for the multi-gram synthesis of both are given. The fourth chapter charts the development of the solid-supported chemistry used to construct PNA-peptide chimeras with close attention to the challenges encountered with incorporating the linker molecules. Of the two chimera targets required. to examine PNA-directcd ligation, a multi-gram preparative synthetic route is presented for one chimera. A route that provides analytical quantities of the complementary chimera is also discussed. The fifth chapter presents the experimental procedures used for the synthesis of the compounds involved in this project. Analytical data and the characterisation of compounds are detailed for each compound where possible.
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Atay, Tolga Baydar Metin Lütfi. « Gelişimsel kalça displazisi zemininde gelişen koksartrozlarda total kalça protezi uygulamalarımız / ». Isparta : SDÜ Tıp Fakültesi, 2004. http://tez.sdu.edu.tr/Tezler/TT00155.pdf.

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Jamieson, Craig. « Total synthesis, structure and function of protein analogues ». Thesis, University of Edinburgh, 1999. http://hdl.handle.net/1842/12283.

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A previously unknown protein produced by an mRNA mutation has recently been identified in Alzheimer's patients. The protein, designated UbN, is composed of the first 75 residues of ubiquitin followed by an unrelated sequence of 20 residues. The synthesis of this 10.7kDa entity was carried out, as well as its purification which was based on a novel affinity support in conjunction with the tetrabenzofluoroene moiety. In vitro testing established how the protein could compromise the ubiquitin-dependent proteolytic system, hence exerting a toxic effect in Alzheimer's patients. The synthesis of an analogue of ubiquitin (76 residues, 8.5kDa), which contained the unnatural amino acid 2S, 4S-5-fluoroleucine in place of leucine at the 50 and 67 positions, has been carried out. A short purification and folding protocol was developed, and comparison of the analogue with the native structure was undertaken. A possible application of the analogue in the study of protein folding using 19F nmr has been examined.
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Wang, Siyao. « Total Synthesis of Homogeneous Glycopeptides and Glycoproteins ». Thesis, The University of Sydney, 2018. http://hdl.handle.net/2123/18329.

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Glycosylation is a ubiquitous post-translational modification of proteins. Access to pure glycoproteins is extremely challenging owing to the enzymatic glycosylation process which is not templated and, as such, affords heterogeneous mixtures of glycoforms. Chemical synthesis provides an attractive avenue to access homogeneously glycosylated peptides and proteins, thus providing a means to elucidate the role of specific glycan modifications on structure and function. This thesis outlined the development of a number of novel synthetic methods to access biologically important glycopeptides and glycoproteins in pure form. Examples would include the synthesis of an unusual glycan modification of arginine which is present on key proteins from pathogenic bacteria and the synthesis of a library of homogenously glycosylated chemokines and cytokines. The results from these studies would inform new anti-infective and anti-inflammatory strategies in the future.
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Smith, Sandra Ellen. « Evaluation of nutritional needs in total parenteral nutrition based on non-protein calories versus total calories ». Thesis, This resource online, 1995. http://scholar.lib.vt.edu/theses/available/etd-03242009-040335/.

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Roche, Didier. « Synthese totale d'inhibiteurs de la protease du virus vih-1 ». Université Louis Pasteur (Strasbourg) (1971-2008), 1995. http://www.theses.fr/1995STR13057.

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La protease aspartique codee par le virus de l'immunodeficience humaine (vih-1) est devenue une cible importante dans la lutte chimiotherapique contre le sida. Un blocage effectif de cette enzyme entraine l'arret de la post-transcription des genes viraux polyproteiniques gag et gag-pol, et produit des virions non infrectieux. Le travail decrit dans ce memoire porte sur la synthese asymetrique d'inhibiteurs dont l'affinite avecl'enzyme a ete prevue par modelisation moleculaire. Dans une premiere approche synthetique, nous avons etudie l'effet des bases dans les reactions d'addition des carbanions de sulfones sur des -alkoxyaldehydes. Nous avons obtenu des bons rendements et une bonne selectivite en utilisant la base de schwesinger tb1-p4. Nous avons montre que la reaction, qui est equilibree, pouvait etre controlee par un effet matrice de la base de schwesinger. Dans un deuxieme temps, nous avons realise la synthese des molecules cibles par l'ouverture regio et stereoselective d'un lactoepoxyde comportant tous les centres asymetriques dans leur configuration desiree. Cette synthese peut etre realisee sur des quantites importantes
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Livres sur le sujet "Protesi totali"

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Liu, Lei, dir. Protein Ligation and Total Synthesis I. Cham : Springer International Publishing, 2015. http://dx.doi.org/10.1007/978-3-319-19186-7.

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Liu, Lei, dir. Protein Ligation and Total Synthesis II. Cham : Springer International Publishing, 2015. http://dx.doi.org/10.1007/978-3-319-19189-8.

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A, Balderston Richard, et Rothman Richard H. 1936-, dir. Total hip arthroplasty. Philadelphia : Saunders, 1988.

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Ohsawa, Kosuke. Total Synthesis of Thielocin B1 as a Protein-Protein Interaction Inhibitor of PAC3 Homodimer. Tokyo : Springer Japan, 2015. http://dx.doi.org/10.1007/978-4-431-55447-9.

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Carroll, Stoianoff, dir. Ray Johnson's Total security : How you can protect yourself from crime. New York : New American Library, 1985.

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Carpender, Dana. Dana Carpender's new carb and calorie counter : Your complete guide to total carbs, net carbs, calories, and more. 4e éd. Beverly, MA : Fair Winds Press, 2009.

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Carpender, Dana. Dana Carpender's new carb and calorie counter : Your complete guide to total carbs, net carbs, calories, and more. 4e éd. Beverly, MA : Fair Winds Press, 2009.

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Dana Carpender's new carb and calorie counter : Your complete guide to total carbs, net carbs, calories, and more. Beverly, MA : Fair Winds Press, 2010.

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C, Atkins Robert. Dr. Atkins' New carbohydrate gram counter : More than 1,300 brand-name and generic foods listed with total carbohydrates, fiber, net carbohydrates, protein, and fat content, plus calories. New York : M. Evans and Co., 2002.

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Webs of resistance : Organizational transformation in a Polish factory. New York : Garland, 1999.

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Chapitres de livres sur le sujet "Protesi totali"

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Innocenti, M., R. Civinini et M. Villano. « La chirurgia mini-invasiva nelle protesi totali di ginocchio ». Dans La protesi di ginocchio di primo impianto, 109–21. Milano : Springer Milan, 2005. http://dx.doi.org/10.1007/88-470-0379-2_7.

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Baerlocher, Mark O. « Total Protein ». Dans Methods to Study Litter Decomposition, 107–14. Cham : Springer International Publishing, 2020. http://dx.doi.org/10.1007/978-3-030-30515-4_12.

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Castelli, C., F. Barbieri et V. Gotti. « La protesi totale di ginocchio ». Dans Osteoporosi : le nuove prospettive in ortopedia e traumatologia, 197–205. Milano : Springer Milan, 2006. http://dx.doi.org/10.1007/978-88-470-0546-4_16.

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Tumani, Hayrettin, et Harald Hegen. « CSF Total Protein ». Dans Cerebrospinal Fluid in Clinical Neurology, 107–9. Cham : Springer International Publishing, 2015. http://dx.doi.org/10.1007/978-3-319-01225-4_8.

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Causero, A., et A. Beltrame. « L’artroprotesi totale di ginocchio : indicazioni e alternative ». Dans La protesi di ginocchio di primo impianto, 1–22. Milano : Springer Milan, 2005. http://dx.doi.org/10.1007/88-470-0379-2_1.

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Fernández-Tejada, Alberto, John Brailsford, Qiang Zhang, Jae-Hung Shieh, Malcolm A. S. Moore et Samuel J. Danishefsky. « Total Synthesis of Glycosylated Proteins ». Dans Protein Ligation and Total Synthesis I, 1–26. Cham : Springer International Publishing, 2014. http://dx.doi.org/10.1007/128_2014_622.

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Spinelli, M., S. Crimaldi et G. Mintrone. « La protesi totale di ginocchio con conservazione del legamento crociato posteriore ». Dans La protesi di ginocchio di primo impianto, 221–27. Milano : Springer Milan, 2005. http://dx.doi.org/10.1007/88-470-0379-2_14.

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Taylor, Justine, Can Wang et D. Jed Harrison. « Multiplexed Protein Preparation Systems for Proteomics ». Dans Micro Total Analysis Systems 2002, 344–46. Dordrecht : Springer Netherlands, 2002. http://dx.doi.org/10.1007/978-94-010-0295-0_115.

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Inerowicz, H. D., F. E. Regnier, S. W. Howell et R. Reifenberger. « Protein Microarrays Fabricated by Microcontact Printing ». Dans Micro Total Analysis Systems 2001, 583–84. Dordrecht : Springer Netherlands, 2001. http://dx.doi.org/10.1007/978-94-010-1015-3_254.

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Yang, Renliang, et Chuan-Fa Liu. « Chemical Methods for Protein Ubiquitination ». Dans Protein Ligation and Total Synthesis I, 89–106. Cham : Springer International Publishing, 2014. http://dx.doi.org/10.1007/128_2014_613.

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Actes de conférences sur le sujet "Protesi totali"

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Daley, V. L., et M. D. Hanigan. « Prediction of total milk fat of dairy cows : a multi-model approach ». Dans 6th EAAP International Symposium on Energy and Protein Metabolism and Nutrition. The Netherlands : Wageningen Academic Publishers, 2019. http://dx.doi.org/10.3920/978-90-8686-891-9_126.

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Gadelha-Parente, T., M. Gouault-Heilmann, G. Rostoker, M. Levent, S. Rafowicz, L. Intrator et G. Lagrue. « TOTAL AND FREE PROTEIN S IN NEPHROTIC SYNDROME ». Dans XIth International Congress on Thrombosis and Haemostasis. Schattauer GmbH, 1987. http://dx.doi.org/10.1055/s-0038-1644296.

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25 consecutive patients (15M, 10F ; mean age 30 years) with nephrotic syndrome (NS) of different grade were studied. Control group consisted in 18 healthy adult volunteers. Total protein S antigen (TPS:Ag) and free protein S antigen (FPS:Ag) after precipitation of C4-BP-bound protein S by PEG 3-5 % final concentration were measured by Laurell's technique. PS:Ag was also searched in concentrated urine of 9 patients by ELISA method, more sensitive than the Laurell's technique. In the same plasma samples we measured C4-BP, Protein C Ag and AT III biological activity (all reagents from D.Stago). Serum albumin level, proteinuria, proteinuria selectivity index, triglycerides, cholesterol levels were recorded. TPS:Ag was found elevated in NS (1.30±0.3 U/ml) in comparison with control group (1.09±0.32 U/ml) and the difference was statistically significant (p<0.05). The mean values of FPS:Ag observed in patients and controls were not statistically different, but if we consider 95 % confidence limits (0.99-1-35 U/ml), 16 pts had normal or elevated FPS:Ag level, whereas 9 had decreased FPS:Ag level. A positive correlation was found between TPS:Ag and FPS:Ag in control group (r=0.66 ; p< 0.001) and in patients with NS (r=0.4l, p<0.05). C4-BP was significantly (p<0.01) increased in nephrotic patients ( 1.37 ± 0.36 U/ml) in comparison with control group (1.04±0.27 U/ml). A negative correlation was found between FPS:Ag and C4-BP levels in control group (r = −0.57, P< 0.01) but not in nephrotic patients. A positive correlation was found between FPS:Ag and albumin level and between FPS:Ag and cholesterol level. No correlation was found between TPS:Ag or FPS:Ag and proteinuria, proteinuria selectivity index, AT III and protein C levels. Traces of PS were found in urine (0. to 2.5 U/day) in 9 patients tested. 2/25 pts suffered thromboembolic events : one had a very low level of FPS:Ag in addition to a decreased level of AT III. The other one had normal FPS:Ag and AT III level but a borderline Protein C level. In conclusion. An acquired FPS:Ag deficiency was observed in 9/25 pts with NS despite an increased level of TPS:Ag. In this small series of patients the acquired FPS deficiency does not seem to be related either to an urinary loss of FPS or to an increased binding to C4-BP, as suggested by some authors.
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Bordean, Despina-Maria, Aurica Breica Borozan, Gabriel Bujanca, Camelia Cioban et Delia Gabriela Dumbrava. « EFFECTS OF BOILING AND ROASTING ON CRUDE PROTEINS, TOTAL ANTIOXIDANT CAPACITY AND TOTAL POLYPHENOLS CONTENT OF POTATO TUBERS ». Dans GEOLINKS International Conference. SAIMA Consult Ltd, 2020. http://dx.doi.org/10.32008/geolinks2020/b1/v2/08.

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Compared with other sources, potato can bring multiple nutritional benefits because it’s naturally low energy food (0.7 kcal), having high water, fiber and starch content. Even if the consummation of potatoes is in decline, it is still considered a source of valuable nutrition. Depending on the method of preparation, potatoes contain significant level of proteins and antioxidants and can offer considerable protection against cardiovascular diseases and cancer. Natural antioxidants are present under different forms in all plants, being the base source of these compounds for humans. The objective of this study was to determine the moisture content, crude protein, total antioxidant capacity and phenolic content of three assortments of potatoes (Solanum tuberosum) available on the Romanian local market (Timis County). The study was carried out on raw, unpeeled, boiled and roasted potatoes. The moisture content was determinate thermogravimetrically using Sartorius thermo balance, crude protein quantified by using a rapid colorimetric method, total antioxidant capacity determinate using CUPRAC method and total polyphenols content using Folin-Ciocalteu assay. The experimental results show that blue roasted potatoes present the highest content of crude protein, total antioxidant capacity and total polyphenols content and the lowest water content. The obtained data are used to create a graphical fingerprint of raw and processed potatoes in order to identify the best options to mix different potatoes assortments and to create innovative nutritious food products
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Olekhnovich, N. I. « DYNAMICS OF TOTAL PROTEIN AND ITS FRACTIONS IN WHEY BLOOD OF PIGS PATIENTS WITH TRICHUROSIS ». Dans DIGEST OF ARTICLES ALL-RUSSIAN (NATIONAL) SCIENTIFIC AND PRACTICAL CONFERENCE "CURRENT ISSUES OF VETERINARY MEDICINE : EDUCATION, SCIENCE, PRACTICE", DEDICATED TO THE 190TH ANNIVERSARY FROM THE BIRTH OF A.P. Stepanova. Publishing house of RGAU - MSHA, 2021. http://dx.doi.org/10.26897/978-5-9675-1853-9-2021-19.

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Porcine trichurosis is a dangerous nematode disease caused by the Trichuris suis nematode of the Trichuridae family. Parasites are localized in the large intestines and cause digestive disorders, decreased appetite, emaciation, and pain in the abdominal wall. It is known that various diseases cause changes in the proteinogram and a shift in the protein composition of the blood correspond to the clinical manifestations of the disease. In this article, the authors present data on changes in blood proteins of healthy and sick piglets with trichurosis. In the first days after infection, the protein picture of the blood of piglets in the experimental and control groups was similar. Changes in the protein spectrum began to appear by 12 days after infection. The amount of total protein in the invasive animals increased in comparison with the control group by 5.4% (P<0.05), and on day 20 by 16.96%. The authors also established quantitative changes in protein fractions: albumin, a-globulin, L-globulin and gamma-globulin. Already from the first days after infection, there is a redistribution of fractions in the proteinogram. The content of albumin on the 5th day after infection of animals with trichocephalosis decreased in comparison with the control by 12.35% (P<0.1), and by 35 and 39 days after infection by 62.8 and 113.37%, respectively (P<0.001) ... Thus, the invasion of pigs with trichuroses leads to a decrease in albumin and an increase in globulin fractions. These changes in protein fractions can be used in the diagnosis of porcine trichurosis.
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5

Williams, Sophie, Zhongmin M. Jin, Martin H. Stone, Eileen Ingham et John Fisher. « The Effect of Different Lubrication Regimes and Lubricants on the Friction Hard-on-Hard Total Hip Replacements ». Dans World Tribology Congress III. ASMEDC, 2005. http://dx.doi.org/10.1115/wtc2005-63330.

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The wear of hip replacements can be dependent on serum protein levels and the swing-phase load during the gait cycle. We hypothesise that these effects may be associated with changes in the lubrication and friction of the joint. The aim of this study was to assess the effect of the lubrication regime and lubricant on the friction of metal-on-metal (MOM) and ceramic-on-ceramic (COC) THRs. Increasing the swing-phase load led to decreased fluid film thickness and an increase in friction, in both MOM and COC bearings. Increasing the protein concentration of the lubricant, decreased the friction of MOM THRs. Friction testing of COC bearings demonstrated an increase in friction as the protein concentration increased. The change in lubricating film thickness explains differences in friction and wear as the swing-phase load is changed for a given lubricant. However, when we change the lubricant composition, protein boundary lubrication effects dominate, this influences friction and wear differently in MOM and COC THRs.
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Lu, Mu, Yu Wang, Yuanyuan Yang, Yu Sun, Jiawei Liang, Ying Hu, Shoubin Liu et Lining Sun. « Prothesis sensor used for soft tissue balancing in total knee arthroplasty ». Dans 2019 IEEE International Conference on Cyborg and Bionic Systems (CBS). IEEE, 2019. http://dx.doi.org/10.1109/cbs46900.2019.9114427.

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Carvajal, J., et S. Kim. « Acute-Phase Protein Concentrations Following Uncomplicated Total Hip Arthroplasty in Dogs ». Dans Abstracts of the 6th World Veterinary Orthopedic Congress. Georg Thieme Verlag KG, 2022. http://dx.doi.org/10.1055/s-0042-1758237.

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Schwarz, H. P., et W. Muntean. « LOW TOTAL PROTEIN S ANTIGEN BUT HIGH PROTEIN S ACTIVITY DUE TO DECREASED C4b-BINDING PROTEIN (C4b-BP) LEVELS IN NEWBORNS ». Dans XIth International Congress on Thrombosis and Haemostasis. Schattauer GmbH, 1987. http://dx.doi.org/10.1055/s-0038-1643610.

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Vitamin K-dependent coagulation proteins are known to be decreased in the neonatal period. So far no data have been published on protein S (PS), the vitamin K-dependent cofactor for the antithrombotic enzyme, activated protein C (APC) in this period. We determined, therefore, PS antigen, PS activity and C4b-BP,a regulatory protein of the classical complement pathway to which PS is complexed, in 36 neonates. Total PS antigen in newborns was below the range associated with thromboembolism in patients congenitally deficient in this protein (22±9.6%, mean±SD). None of these infants had clinical or laboratory evidence of thromboembolism or DIC. In contrast to the PS antigen level PS activity measured by the ability of APC to prolong the clotting time of a modified APTT assay using PS-immunodep1eted plasma was significantly higher (77.6±14%, mean±SD, p< 0,001), suggesting a shift in PS to the free form. In fact two dimensional immunoe1ectrophoresis studies revealed the absence of protein S-C4b-BP complexes and only one precipitation indicating free PS was seen in 15 out of the 36 infants. In these 15 neonates C4b-BP was below the limit of detection by sensitive quantitative immunob1otting techniques using monoclonal or polyclonal antibodies. In the remaining 21 infants PS-C4b-BP complexes were detected, but in contrast to adult normal plasma approximately 80% of PS was found in the free form. Mixing experiments with normal human plasma and newborn’s plasma indicate that PS in neonate deficient of C4b-BP can bind normally to C4bp. Absence of C4b-BP did not correlate to gestational age. If an equilibrium distribution of PS between bound and free form regulates the cofactor activity of PS for the anticoagulant and profibrino 1ytic properties of APC in normal adults, our study demonstrates that the absence of PS-C4b-BP complexes in newborns and the presence of free PS only may contribute to the increased bleeding risk of premature infants.
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Ploos van Amstel, J. K., A. L. van der Zanden, P. H. Reitsma et R. M. Bertina. « RESTRICTION ANALYSIS AND SOUTHERN BLOTTING OF TOTAL HUMAN DNA REVEALS THE EXISTENCE OF MORE THAN ONE GENE HOMOLOGOUS WITH PROTEIN S cDNA ». Dans XIth International Congress on Thrombosis and Haemostasis. Schattauer GmbH, 1987. http://dx.doi.org/10.1055/s-0038-1644639.

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A deficiency in protein S, the cofactor of activated protein C, is associated with an increased risk for the development of venous thrombosis. It is inherited as an autosomal dominant disorder. To improve the detection of heterozygotes in affected families, we have started to search for restriction fragment length polymorphism (RFLP) in the protein S gene. This study revealed the existence of two genes containing sequences homologous to protein S cDNA.Three non-overlapping fragments of clone pSUL5, which codes for the carboxy-terminal part of protein S and contains the complete 3' untranslated region, were isolated and used as probes in search for RFLP of the protein S gene.Surprisingly the non-overlapping probes shared more than one hybridizing band. The hybridization took place under stringent assay conditions.This observation is contradictory to the intron-exon organization of a gene and suggests the existence of two genes, containing sequences homologous with pSUL5. Both genes could be assigned to chromosome 3 by mapping through somatic cell hybrids. Whether two functional protein S genes are present in the human genome remains to be established.
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Malm, J., R. Bennhagen, L. Holmberg et B. Dahlbäck. « LOW PLASMA CONCENTRATIONS OF C4b-BINDING PROTEIN AND VITAMIN K-DEPENDENT PROTEIN S IN PRETERM INFANTS WITH DECREASED FORMATION OF PROTEIN S-C4b-BINDING PROTEIN COMPLEXES ». Dans XIth International Congress on Thrombosis and Haemostasis. Schattauer GmbH, 1987. http://dx.doi.org/10.1055/s-0038-1644265.

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Protein S is a vitamin K-dependent plasmaprotein functioning as a non-enzymatic cofactor to the activated form of protein C in the degradation of coagulationfactors Va and VIIa. In the circulation approximately 60% of protein S is complexed to the complement protein C4b-binding protein (C4BP). Only the remaining, free fraction exhibits protein Ca cofactor activity.The plasma concentrations of protein S and C4BP were determined in 25 term and 26 preterm infants. Both proteins werequantified with radioimmunoassays. The free, functionally active form of proteinS and the total protein S concentration were determined separately. The level ofC4BP in preterm infants was found to be very low (mean 6% of the adult level). In term infants the level had increased to a mean of 18%. Also the total concentration of protein S was decreased in preterm as well as in term infants; 18% and 31% of the adult level, respectively. Free protein S was the predominant form in plasma representing 83 % of total protein S in preterm and 68 % in term infants. This was probably due to the very low C4BP levels. In adult controls the corresponding value was 34%. The plasma concentration of free protein S in preterm and term infants, when compared to the adult level, was 44% and 66%, respectively. These results demonstrate that although the total protein S concentration in preterm and term infants was very low when compared to adult levels, the difference in the concentration of free, functionally active protein S between infants and adults was less pronounced.
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Rapports d'organisations sur le sujet "Protesi totali"

1

Barash, Itamar, et Robert E. Rhoads. Translational Mechanisms that Govern Milk Protein Levels and Composition. United States Department of Agriculture, novembre 2004. http://dx.doi.org/10.32747/2004.7586474.bard.

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Original objectives: The long term objective of the project is to achieve higher content of protein in the milk of ruminants by modulating the translational machinery in the mammary gland. The first specific aim of the BARD proposal was to characterize responsiveness of various experimental systems to combination of lactogenic hormones and amino acids with particular emphasis on discrimination between the control of total protein synthesis and milk protein synthesis. Based on the results, we planned to proceed by characterizing the stage of protein synthesis in which the stimulation by lactogenic hormones and amino acid occur and finally we proposed to identify which components of the translation machinery are modified. Background to the topic: Milk protein is the most valuable component in milk, both for direct human consumption and for manufacturing cheese and other protein-based products. Attempts to augment protein content by the traditional methods of genetic selection and improved nutritional regimes have failed. The proposal was based on recent results suggesting that the limiting factor for augmenting protein synthesis in the bovine mammary gland is the efficiency of converting amino acids to milk proteins. Major conclusions, solutions, achievements: Insulin and prolactin synergistically stimulate â-casein mRNA translation by cytoplasmatic polyadenylation. The interaction between insulin and prolactin was demonstrated two decades ago as crucial for milk-protein synthesis, but the molecular mechanisms involved were not elucidated. We found in differentiated CID 9 mouse mammary epithelial cells line that insulin and prolactin synergistically increases the rate of milk protein mRNA translation. We focused on â-casein, the major milk protein, and found that the increase in â-casein mRNA translation was reflected in a shift to larger polysomes, indicating an effect on translational initiation. Inhibitors of the PI3K, mTOR, and MAPK pathways blocked insulin-stimulated total protein and â-casein synthesis but not the synergistic stimulation. Conversely, cordycepin, a polyadenylation inhibitor, abolished synergistic stimulation of protein synthesis without affecting insulin-stimulated translation. The poly(A) tract of â-casein mRNA progressively increased over 30 min of treatment with insulin plus prolactin. The 3’-untranslated region of â-casein mRNA was found to contain a cytoplasmic polyadenylation element (CPE), and in reporter constructs, this was sufficient for the translational enhancement and mRNA-specific polyadenylation. Furthermore, insulin and prolactin stimulated phosphorylation of cytoplasmic polyadenylation element binding protein (CPEB) but did not increase cytoplasmic polyadenylation.
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Varga, Gabriella A., Amichai Arieli, Lawrence D. Muller, Haim Tagari, Israel Bruckental et Yair Aharoni. Effect of Rumen Available Protein, Amimo Acids and Carbohydrates on Microbial Protein Synthesis, Amino Acid Flow and Performance of High Yielding Cows. United States Department of Agriculture, août 1993. http://dx.doi.org/10.32747/1993.7568103.bard.

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The effect of rumen available protein amino acids and carbohydrates on microbial protein synthesis, amino acid flow and performance of high yielding dairy cows was studied. A significant relationship between the effective degradabilities of OM in feedstuffs and the in vivo ruminal OM degradation of diets of dairy cows was found. The in situ method enabled the prediction of ruminal nutrients degradability response to processing of energy and nitragenous supplements. The AA profile of the rumen undegradable protein was modified by the processing method. In a continuous culture study total N and postruminal AA flows, and bacterial efficiency, is maximal at rumen degradable levels of 65% of the CP. Responses to rumen degradable non carbohydrate (NSC) were linear up to at least 27% of DM. Higher CP flow in the abomasum was found for cows fed high ruminally degradable OM and low ruminally degradable CP diet. It appeared that in dairy cows diets, the ratio of rumen degradable OM to rumenally degradable CP should be at least 5:1 in order to maximize postruminal CP flow. The efficiency of microbial CP synthesis was higher for diets supplemented with 33% of rumen undegradable protein, with greater amounts of bacterial AA reaching the abomasum. Increase in ruminal carbohydrate availability by using high moisture corn increased proportions of propionate, postruminal nutrients flow, postruminal starch digestibility, ruminal availability of NSC, uptake of energy substrates by the mammory gland. These modifications resulted with improvement in the utilization of nonessential AA for milk protein synthesis, in higher milk protein yield. Higher postruminal NSC digestibility and higher efficiency of milk protein production were recorded in cows fed extruded corn. Increasing feeding frequency increased flow of N from the rumen to the blood, reduced diurnal variation in ruminal and ammonia, and of plasma urea and improved postruminal NSC and CIP digestibility and total tract digestibilities. Milk and constituent yield increased with more frequent feeding. In a study performed in a commercial dairy herd, changes in energy and nitrogenous substrates level suggested that increasing feeding frequency may improve dietary nitrogen utilization and may shift metabolism toward more glucogenesis. It was concluded that efficiency of milk protein yield in high producing cows might be improved by an optimization of ruminal and post-ruminal supplies of energy and nitrogenous substrates. Such an optimization can be achieved by processing of energy and nitrogenous feedstuffs, and by increasing feeding frequency. In situ data may provide means for elucidation of the optimal processing conditions.
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Barash, Itamar, et Robert Rhoads. Translational Mechanisms Governing Milk Protein Levels and Composition. United States Department of Agriculture, 2006. http://dx.doi.org/10.32747/2006.7696526.bard.

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Original objectives: The long-term goal of the research is to achieve higher protein content in the milk of ruminants by modulating the translational apparatus of the mammary gland genetically, nutritionally, or pharmacologically. The short-term objectives are to obtain a better understanding of 1) the role of amino acids (AA) as regulators of translation in bovine and mouse mammary epithelial cells and 2) the mechanism responsible for the synergistic enhancement of milk-protein mRNA polyadenylation by insulin and prolactin. Background of the topic: In many cell types and tissues, individual AA affect a signaling pathway which parallels the insulin pathway to modulate rates and levels of protein synthesis. Diverse nutritional and hormonal conditions are funneled to mTOR, a multidomain serine/threonine kinase that regulates a number of components in the initiation and elongation stages of translation. The mechanism by which AA signal mTOR is largely unknown. During the current grant period, we have studied the effect of essential AA on mechanisms involved in protein synthesis in differentiated mammary epithelial cells cultured under lactogenic conditions. We also studied lactogenic hormone regulation of milk protein synthesis in differentiated mammary epithelial cells. In the first BARD grant (2000-03), we discovered a novel mechanism for mRNA-specific hormone-regulated translation, namely, that the combination of insulin plus prolactin causes cytoplasmic polyadenylation of milk protein mRNAs, which leads to their efficient translation. In the current BARD grant, we have pursued the signaling pathways of this novel hormone action. Major conclusions/solutions/achievements: The positive and negative signaling from AA to the mTOR pathway, combined with modulation of insulin sensitization, mediates the synthesis rates of total and specific milk proteins in mammary epithelial cells. The current in vitro study revealed cryptic negative effects of Lys, His, and Thr on cellular mechanisms regulating translation initiation and protein synthesis in mammary epithelial cells that could not be detected by conventional in vivo analyses. We also showed that a signaling pathway involving Jak2 and Stat5, previously shown to lead from the prolactin receptor to transcription of milk protein genes, is also used for cytoplasmic polyadenylation of milk protein mRNAs, thereby stabilizing these mRNAs and activating them for translation. Implications: In vivo, plasma AA levels are affected by nutritional and hormonal effects as well as by conditions of exercise and stress. The amplitude in plasma AA levels resembles that applied in the current in vitro study. Thus, by changing plasma AA levels in the epithelial cell microenvironment or by sensitizing the mTOR pathway to their presence, it should be possible to modulate the rate of milk protein synthesis. Furthermore, knowledge that phosphorylation of Stat5 is required for enhanced milk protein synthesis in response to lactogenic opens the possibility for pharmacologic approaches to increase the phosphorylation of Stat5 and, thereby, milk protein production.
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Huber, John Tal, Joshuah Miron, Brent Theurer, Israel Bruckental et Spencer Swingle. Influence of Ruminal Starch Degradability on Performance of High Producing Dairy Cows. United States Department of Agriculture, janvier 1994. http://dx.doi.org/10.32747/1994.7568748.bard.

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This research project entitled "Influence of Ruminal Starch Degradability on Performance of High Producing Dairy Cows" had the following objectives: a) Determine effects of feeding varying amounts of ruminally degradable starch (RDS) on efficiency of milk and milk protein production; and 2) Investigate digestive and metabolic mechanisms relating to lactation responses to diets varying in ruminal and total starch degradability. Four lactation studies with high producing cows were conducted in which steam-flaked (~ 75% RDS) was compared with dry-rolled sorghum (~ 50% RDS) grain. All studies demonstrated increased efficiency of conversion of feed to milk (FCM/DMI) and milk protein as amount of RDS in the diet increased by feeding steam-flaked sorghum. As RDS in diets increased, either by increased steam-flaked sorghum, grinding of sorghum, or increasing the proportion of wheat to sorghum, so also did ruminal and total tract digestibilities of starch and neutral-detergent soluble (NDS) carbohydrate. Despite other research by these two groups of workers showing increased non-ammonia N (NAN) flowing from the rumen to the duodenum with higher RDS, only one of the present studies showed such an effect. Post-absorptive studies showed that higher dietary RDS resulted in greater urea recycling, more propionate absorption, a tendency for greater output of glucose by the liver, and increased uptake of alpha-amino nitrogen by the mammary gland. These studies have shown that processing sorghum grain through steam-flaking increases RDS and results in greater yields and efficiency of production of milk and milk protein in high producing dairy cows.
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Erdman, Richard, Geoffrey Dahl, Hanina Barash, Israel Bruckental, Avi Shamay et Anthony Capuco. Management Strategies to Maximize Skeletal Growth Rate in Dairy Heifers. United States Department of Agriculture, juillet 2002. http://dx.doi.org/10.32747/2002.7695848.bard.

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The objectives of this study were to determine the effects of recombinant bovine somatotropin (bST) and added dietary rumen undegradable protein (RUP) on organ and tissue weights and body composition in growing dairy heifers. A total of 32 Holstein heifers, 3 months of age at the beginning of the study were used in the experiment. Eight heifers were slaughtered at 3 mo of age to determine pre- treatment body composition. The remaining heifers were randomly assigned to treatments (n=6) consisting of 0.1 mg/kg body weight per day of bST and 2% added dietary RUP (dry matter basis) applied in a 2X2 factorial design. A total of six heifers per treatment group (3 each at 5 and 10 mo of age), were slaughtered to determine body composition an organ masses. There was a trend for increased live and empty body weights (EB:W), carcass and non-carcass components for heifers treated with bST or fed RUP. Added RUP increased rumen and reticulum weights whereas administration of bST tended to increase the weights of small and large intestine at 10 months of age by 22 % and 26%, respectively. Spleen, heart, and kidney weights at 10 months of age were increased 36%, 28% and 23% for bST treatments respectively, compared with controls. Rates of ash and protein deposition between 3 and 10 months of age were increased by bST by 7.2 g/d and 28.9 g/d, respectively, while no treatment differences were observed for rates of fat and energy deposition. Bovine somatotropin significantly altered the metabolism of growing heifers in a manner that led to increased protein and ash deposition, and tended to reduce fat percentage, and there was a similar tendency observed with added RUP. This suggests that nutritional and endocrine manipulations could increase growth rates of skeletal and lean tissues without increasing fat deposition in prepubertal dairy heifers.
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Dolja, Valerian V., Amit Gal-On et Victor Gaba. Suppression of Potyvirus Infection by a Closterovirus Protein. United States Department of Agriculture, mars 2002. http://dx.doi.org/10.32747/2002.7580682.bard.

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The plant virus family Polyviridae is the largest and most destructive of all plant viruses. Despite the continuous effort to develop resistant plant varieties, there is a desperate need for novel approaches conferring wide-range potyvirus resistance. Based on experiments with the tobacco etch potyvirus (TEV)-derived gene expression vector, we suggested approach for screening of the candidate resistance genes. This approach relies on insertion of the genes into a virus vector and evaluation of the phenotypes of the resulting recombinant viruses. The genes which suppress infection by the recombinant virus are selected as candidates for engineering transgenic resistance. Our analysis of the TEV variants expressing proteins of the beet yellows closterovirus (BYV) revealed that one of those, the leader proteinase (L-Pro), strongly and specifically interfered with the hybrid TEV infection. Since closterovirus L-Pro is evolutionary related to potyviral helper component-proteinase (HC-Pro), we suggested that the L-Pro interfered with HC-Pro function via a trans-dominant inhibitory effect. Based on these findings, we proposed to test two major hypotheses. First, we suggested that L-Pro-mediated suppression of potyvirus infection is a general phenomenon effective against a range of potyviruses. The second hypothesis stated that the suppression effect can be reproduced in transgenic plants expressing L-Pro, and can be utilized for generation of resistance to potyviruses. In accord with these hypotheses, we developed two original objectives of our proposal: A) to determine the range of the closterovirus-derived suppression of potyviral infection, and B) to try and utilize the L-Pro-mediated suppression for the development of transgenic resistance to potyviruses. In the first phase of the project, we have developed all major tools and technologies required for successful completion of the proposed research. These included TEV and ZYMV vectors engineered to express several closteroviral L-Pro variants, and generation of the large collection of transgenic plants. To our satisfaction, characterization of the infection phenotypes exhibited by chimeric TEV and ZYMV variants confirmed our first hypothesis. For instance, similar to TEV-L- Pro(BYV) chimera, ZYMV-L-Pro(LIYV) chimera was debilitated in its systemic spread. In contrast, ZYMV-GUS chimera (positive control) was competent in establishing vigorous systemic infection. These and other results with chimeric viruses indicated that several closteroviral proteinases inhibit long-distance movement of the potyviruses upon co-expression in infected plants. In order to complete the second objective, we have generated ~90 tobacco lines transformed with closteroviral L-Pro variants, as well as ~100 lines transformed with BYV Hsp70-homolog (Hsp70h; a negative control). The presence and expression of the trans gene in each line was initially confirmed using RT-PCR and RNA preparations isolated from plants. However, since detection of the trans gene-specific RNA can not guarantee production of the corresponding protein, we have also generated L-Pro- and Hsp70h-specific antisera using corresponding synthetic peptides. These antisera allowed us to confirm that the transgenic plant lines produced detectable, although highly variable levels of the closterovirus antigens. In a final phase of the project, we tested susceptibility of the transgenic lines to TEV infection. To this end, we determined that the minimal dilution of the TEV inoculum that is still capable of infecting 100% of nontransgenic plants was 1:20, and used 10 plants per line (in total, ~2,000 plants). Unfortunately, none of the lines exhibited statistically significant reduction in susceptibility. Although discouraging, this outcome prompted us to expand our experimental plan and conduct additional experiments. Our aim was to test if closteroviral proteinases are capable of functioning in trans. We have developed agroinfection protocol for BYV, and tested if co- expression of the L-Pro is capable of rescuing corresponding null-mutant. The clear-cut, negative results of these experiments demonstrated that L-Pro acts only in cis, thus explaining the lack of resistance in our transgenic plants. We have also characterized a collection of the L-Pro alanine- scanning mutants and found direct genetic evidence of the requirement for L-Pro in virus systemic spread. To conclude, our research supported by BARD confirmed one but not another of our original hypotheses. Moreover, it provided an important insight into functional specialization of the viral proteinases and generated set of tools and data with which we will be able to address the molecular mechanisms by which these proteins provide a variety of critical functions during virus life cycle.
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Wicker, Louise, et Nissim Garti. Entrapment and controlled release of nutraceuticals from double emulsions stabilized by pectin-protein hybrids. United States Department of Agriculture, octobre 2004. http://dx.doi.org/10.32747/2004.7695864.bard.

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Original Objectives Specific objectives are to: (1) modify charge and hydrophobicity of pectins to improve emulsion stabilizing properties (2) develop emulsions that can be sterically stabilized using modified pectins and/or pectin/protein hybrids (3) obtain submicronal inner emulsion droplets (10-50 nanometers) with small and monodispersed double emulsion (1-2 μm) droplets with long-term stability (possibly by emulsified microemulsions) and (4) trigger and control the release at will. Background Methodology for encapsulation and controlled release of selected addenda, e.g. drugs, vitamins, phytochemicals, flavors, is of major impact in the food industries. Stable double emulsions with desired solubilization and release properties of selected addenda are formed using charge modified pectin or pectin-protein hybrids. Major conclusions, solutions, achievements * We developed methodology to isolate PME isozymes and prepared modified pectins in sufficient quantity to characterize, form single and double emulsions and test stability. *Amino acid sequence of PME isozymes was estimated and will facilitate cloning of PME for commercial application * The contribution of total charge and distribution of charge of modified pectin was determined *Soluble complexes or modified pectins and whey isolates are formed * Stable W/O/W double emulsions were formed that did not cream, had small particle size * Inner phase of double emulsions are nano-sized and stable. These new structures were termed emulsified microemulsions (EME) * Release of bioactives were controlled between a few days to months depending on layering on droplets by hybrids * Commercial testing by Israeli company of stability and release of Vitamin C showed good chemical stability Implications Resolved the major stability limitation of W/O/W emulsions. Resolved the questions regarding citrus PMEs and tailored pilot scale modification of pectins.
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Rocheford, Torbert, Yaakov Tadmor, Robert Lambert et Nurit Katzir. Molecular Marker Mapping of Genes Enhancing Tocol and Carotenoid Composition of Maize Grain. United States Department of Agriculture, décembre 1995. http://dx.doi.org/10.32747/1995.7571352.bard.

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The overall objective of this research was to identify chromosomal regions and candidate genes associated with control of concentration and forms of carotenoids (includes pro-Vitamin A) and tocopherols (Vitamin E), which are both antioxidants and are associated with health advantages. Vitamin A and E are included in animal feeding supplements and the eventual goal is to increase levels of these compounds in maize grain so that the cost of these supplements can be reduced or eliminated. Moreover, both compounds are antioxidants that protect unsaturated fatty acids from oxidation and thus maintaining maize oil quality for longer periods. We identified three SSR markers that are associated with 38% of the variation for total carotenoids and three SSR markers associated with 44% of the variation for total tocopherols in the cross W64a x A632. We identified two candidate genes associated with levels of carotenoids: phytoene synthase and zeta carotene desaturase. Evaluation of (Illinois High Oil x B73) B73 BC 1S1 population for tocopherols detected additional chromosomal regions influencing the level of total tocopherols, and detected a common region on chromosome 5 associated with ratio of the more desirable alpha from to the gamma form of tocopherol. The results suggest molecular marker assisted selection for higher levels of these antioxidants in corn grain should be feasible.
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Terzyan, Aram. Belarus in the Wake of a Revolution : Domestic and International Factors. Eurasia Institutes, décembre 2020. http://dx.doi.org/10.47669/eea-3-2020.

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This paper explores the political landscape of Belarus in the aftermath of the 2020 presidential elections, with a focus on both domestic and international factors behind the ongoing crisis. Lukashenko’s regime has a long record of sustaining its power by preserving elite unity, controlling elections, and/or using force against opponents. Therefore, massive fraud characterizing the 2020 presidential elections and brutal suppression of peaceful protests in its aftermath came as no surprise. Against this backdrop, the anti-government protests following the presidential elections raised a series of unanswered questions regarding both their domestic and foreign policy implications. The biggest question is whether the Belarusian civil society and opposition will prove powerful enough to overcome state repression and change the status quo in Europe’s “last dictatorship”. Worries remain about the Belarusian opposition’s emphasis on foreign policy continuity, meaning that Belarus is bound to remain in the orbit of the Russian authoritarian influence. The total fiasco of post-Velvet Revolution Armenian government both in terms of domestic and foreign policies, among others, further reveals the excruciating difficulties of a democratic state-building within the Russia-led socio-political order.
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Ham, Andrés, Angela Guarin et Juanita Ruiz. How Accurately are Household Surveys Measuring the Size and Inequalities for the LGBT Population in Bogota, Colombia ? Evidence from a List Experiment. Inter-American Development Bank, février 2023. http://dx.doi.org/10.18235/0004721.

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This paper studies whether household surveys precisely identify the LGBT population and are suitable to measure labor market discrimination in Colombia. We first quantify the size of the LGBT population and estimate labor market inequalities from these data, highlighting potential pitfalls from using this approach. We then present findings from a list experiment in Bogotá, Colombia. Results show that household surveys underestimate the size of the LGBT population and may yield biased estimates of labor market inequalities. While survey estimates range between 1-4%, we find that LGBT people constitutes around 12-22% of the total population. We find heterogeneous reporting by sex, age groups, educational attainment, and marital status. Our findings suggest that while current measurement practices are a step forward for the LGBT populations statistical visibility, additional steps are required before household surveys may be used to consistently estimate discrimination and guide policy responses to protect this population.
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