Littérature scientifique sur le sujet « Produits biologiques – synthèse chimique »
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Articles de revues sur le sujet "Produits biologiques – synthèse chimique"
Mansour, Hedi Ben, Oualid Boughzala, dorra Dridi, Daniel Barillier, Leila Chekir-Ghedira et Ridha Mosrati. « Les colorants textiles sources de contamination de l’eau : CRIBLAGE de la toxicité et des méthodes de traitement ». Revue des sciences de l’eau 24, no 3 (28 novembre 2011) : 209–38. http://dx.doi.org/10.7202/1006453ar.
Texte intégralFassinou, Nonvignon Martial, Fadéby Modeste Gouissi, Souradjou Orou Goura, Wakili Bolatito Yessoufou et Tayéwo Sylvain Biaou. « Impact De La Contamination Agricole Sur La Qualité Physico-Chimique Et Biologique Des Eaux De Surface : Synthèse Bibliographique ». International Journal of Progressive Sciences and Technologies 39, no 1 (19 juin 2023) : 64. http://dx.doi.org/10.52155/ijpsat.v39.1.5289.
Texte intégralAgbodan, Kokou Agbékonyi, Oudjaniyobi Simalou, Gneiny Whad Tchani et Koffi Jondo. « Etude de l’influence de la basicité sur l’enthalpie de réaction des sels N-méthoxycarbonyl-(oxy)-pyridiniums ». International Journal of Biological and Chemical Sciences 14, no 4 (17 août 2020) : 1489–98. http://dx.doi.org/10.4314/ijbcs.v14i4.26.
Texte intégralBINI, Kouadio Kra Norbert, Malanno KOUAKOU, Mathias DANHO et Ochou Germain OCHOU. « Activité insecticide de Bacillus subtilis thurigiensis kurstaki sur les principaux insectes ravageurs du cotonnier ». Journal of Applied Biosciences 171 (31 mars 2022) : 17786–94. http://dx.doi.org/10.35759/jabs.171.2.
Texte intégralAkantetou, Pikassalé K., Nafadjara A. Nadio, Magnim E. Bokobana, Panawé Tozoou, Pali Kilimou, Koffi Koba, Wiyao Poutouli, Christine Raynaud et Komla Sanda. « Effet aphicide de l’huile essentielle de Ocimum basilicum L. et de son composé majoritaire sur le puceron du cotonnier Aphis gossypii Glover (Homoptera : Aphididae) au Togo ». International Journal of Biological and Chemical Sciences 14, no 1 (3 avril 2020) : 84–96. http://dx.doi.org/10.4314/ijbcs.v14i1.8.
Texte intégralKarila, L. « Les nouveaux produits de synthèse : données cliniques et pistes thérapeutiques ». European Psychiatry 30, S2 (novembre 2015) : S59. http://dx.doi.org/10.1016/j.eurpsy.2015.09.164.
Texte intégralDeguine, Jean-Philippe. « Lutte biologique et biocontrôle : un besoin de clarification ». Cahiers Agricultures 32 (2023) : 11. http://dx.doi.org/10.1051/cagri/2023004.
Texte intégralCloutier, Conrad, Jean-Marie Perron et Christine Jean. « Extraits de l'évolution de l'entomologie appliquée au Québec : emphase sur la phytoprotection ». Phytoprotection 89, no 2-3 (20 novembre 2009) : 79–97. http://dx.doi.org/10.7202/038236ar.
Texte intégralMaujean, Alain. « The chemistry of sulphur in musts and wines ». OENO One 35, no 4 (31 décembre 2001) : 171. http://dx.doi.org/10.20870/oeno-one.2001.35.4.1698.
Texte intégralAouadi, Nawel, Francis Macary et Adeline Alonso Ugaglia. « Évaluation multicritère des performances socio-économiques et environnementales de systèmes viticoles et de scénarios de transition agroécologique ». Cahiers Agricultures 29 (2020) : 19. http://dx.doi.org/10.1051/cagri/2020016.
Texte intégralThèses sur le sujet "Produits biologiques – synthèse chimique"
Decret, Laurent. « Synthèse de sondes biologiques marquées par des émetteurs [gamma] ». Université Joseph Fourier (Grenoble), 2000. http://www.theses.fr/2000GRE10047.
Texte intégralDao, Vi Thuy. « Le gossypol et ses nouveaux dérivés : synthèse et étude d'activités biologiques ». Paris 11, 2002. http://www.theses.fr/2002PA112286.
Texte intégralNew Schiff bases of racemic gossypol and gossypolone and of (+)- or (-)-gossypol enantiomers are described. Schiff bases obtained from gossypol enantiomers are optically stable at room temperature whereas gossypolone Schiff bases racemize quickly and may be observed only at lower temperatures. Their cytotoxic activities on KB human cancer cells were determined : the methylimine and ethylimine derivatives of racemic gossypolone were the most active compounds, and the cytotoxicity of racemic gossypol and gossypolone was increased when the tests were performed in the absence of serum and decreased when catalase as well as mannitol were added to the culture medium. (+)-gossypol and (-)-gossypol derivatives displayed higher toxicities on KS and MCF7 cells than the corresponding (+) isomers. New derivatives of gossypol and gossypolone: dithianes or dithiolanes, were synthesized using dithioethane or dithiopropane in the presence of BF3. Et2O. Furthermore, the same reaction conditions with tetramethyl or hexamethyl ethers of gossypol lead to cyclic thioderivatives. These thioderivatives exhibited very low toxicity in KB cells. This masking of the aldehyde groups may be reverted by the use of electrophiles such as nitroxide ions, nitrosonium tetrafluoroborate which regenerate gossypolone or transform thiogossypols in new compounds, more toxic. Since toxicities of the derivatives issued from nitrosonium tetraf luoroborate action or nitric oxide plus ferric ion are increased, these results support the hypothesis that gossypol and gossypolone dithiane and dithiolanes could be proposed as prodrugs targeted against cells that express or are surrounded by high concentrations of nitric oxide, for instance, tumor cells
Pérusse, Dimitri. « Synthèse et évaluation physico-chimique de tensioactifs biosourcés pour l’industrie cosmétique ». Rennes, Ecole nationale supérieure de chimie, 2013. http://www.theses.fr/2013ENCR0017.
Texte intégralNeuberg, Patrick. « Isolement de substances antimicrobiennes d'insectes : Synthèse chimique et préparation d'analogues structuraux ». Université Louis Pasteur (Strasbourg) (1971-2008), 2002. https://publication-theses.unistra.fr/public/theses_doctorat/2002/Neuberg_Patrick_2002_ED222.pdf.
Texte intégralInsects are famous for their strong resistance against invading microorganisms. Their immune response is based on a diverse set of inducible antimicrobial peptides. We addressed the question of whether there are other non-peptidic antimicrobial molecules reinforcing the immune response of the insects. In this work we describe the characterization of an antimicrobial diamine, which was isolated using a bioassay guide, from the coccinellid species Harmonia axyridis. This beetle biosynthesises the Z-1,17-diaminooctadec-9-ene, also called ‘harmonine’. It is the first time that the antimicrobial activities of this substance have been described. The chemical synthesis of diverse α,ω-diamines allowed for a detailed analysis of the structure-activity relationship of this family of compounds. This study showed which structural elements are essential for their biological activity. We showed that the active molecules could be diversely substituted at their central part; leading from this, novel polyamines, based on a branched hydrocarbon skeleton, were designed. These have an increased activity compared to the isolated natural diamine. We also describe the novel construction and synthesis of rigidified analogues of the polyamines, which are based on a tetrahydrofuran heterocycle. These THF-amines are endowed with the same activities as the most potent polyamines of these series. Unlike the polyamines based on a branched hydrocarbon part, the THF-amines show no cytotoxic properties as proved by hemolytic tests. The therapeutic index of the polyamines is increased as compared to harmonine
Belalia, Rachid. « Synthèse d'un biocide par modification chimique de chitosanePréservation du bois , préservation des aliments ». Bordeaux 1, 2006. http://www.theses.fr/2006BOR13142.
Texte intégralRuggieri, Francesca. « Putting nature back into drug discovery : selection, design and synthesis of bioinspired chemical libraries for the discovery of new antibacterials ». Electronic Thesis or Diss., Université de Lille (2022-....), 2024. http://www.theses.fr/2024ULILS013.
Texte intégralNatural products (NPs) have declined in popularity since the introduction of synthetic small molecules several years ago. Many are the reasons behind this choice, such as difficulties in access and supply, complexities of NP chemistry and the advent of combinatorial chemistry. However, NPs offer many interesting properties compared to conventional synthetic molecules, which confer both advantages and challenges for the drug discovery process. Usually, NPs are characterized by a higher number of sp3 carbons and stereogenic centres, large scaffold diversity and structural complexity. With half of the drugs approved by the FDA since 1994 being NPs or hemisynthetic derivatives and the recent stagnation in new drug research and development, it is becoming more and more evident that NPs should be reintroduced in the drug discovery process as a source of inspiration.Therefore, many strategies are now emerging for the construction of nature-inspired chemical libraries, such as “top-down” and “bottom-up” strategies. In “bottom-up” approaches, complexity is created starting from simple building blocks. On the other hand, “top-down” approaches are assumed to make structural modifications to an already complex NP.Our presented work describes two different approaches to enrich the chemical library of our research unit with NP-derived compounds. A “top-down” semisynthetic strategy was planned to obtain derivatives of lactucin and 11β,13-dihydrolactucin, two sesquiterpene lactones extracted from chicory roots. Thirty-six ester derivatives were synthesized in three steps (classical synthesis), together with two amine derivative libraries (using parallel synthesis). All the compounds were then tested against Mycobacterium tuberculosis and some promising hits were found (MICGFP < 1.2 μM). On the other hand, a “bottom-up” strategy allowed the synthesis of two analogues of the known natural antibiotic hygromycin A. This approach started from simple commercially available building blocks and employed a dearomatization strategy in the synthetic process.Together, we explored a broader chemical space, increased the structural diversity of our chemical library and discovered new potential antibacterial hits. Moreover, this work paves the way for the discovery of new antibacterial targets
Vives, Eric. « Synthèse chimique et études biologiques de la protéine transactivatrice Tat du virus de l'immunodéficience humaine (VIH) ». Aix-Marseille 3, 1992. http://www.theses.fr/1992AIX30090.
Texte intégralChaouni-Benabdallah, Aziz. « Synthèse et étude physico-chimique de nouveaux aminoxyles hydroxyméthylés et méthoxyméthylés dérivés du doxyl ». Montpellier 1, 1993. http://www.theses.fr/1993MON13502.
Texte intégralRenault, Benjamin. « Nouveaux tensioactifs dérivés des polyglycosides d'alkyle. Synthèse et évaluation physico-chimique ». Reims, 2009. http://theses.univ-reims.fr/sciences/2009REIMS002.pdf.
Texte intégralThis work deals with the synthesis, the physical and chemical evaluation of new surfactants derived from sugars and succinic acid in the fields of cosmetics and detergents. We start presenting Alkyl PolyGlycosides of 1st, 2nd and 3rd generation and the targeted molecules. At the end of our research, we succeeded in optimizing synthesis conditions (solvent-free reaction by heat activation) from succinic anhydride and acid to obtain mixture of polydisperse O-Succinyl Alkyl PolyGlycosides more or less substituted. We synthesized a complete range of O-Succinyl Alkyl PolyGlycosides by varying their sugar head nature (Arabinose, Xylose and Glucose) and size (DP=Degree of Polymerisation between 1,1 and 2,2), their alkyl chain length (8, 8/10, 10, 12, 12/14 carbone atoms) and Substitution Degree (DS=number of unit esters between 0 and 2,9). The second part concerns the physical and chemical evaluation and the toxicity profile of these surfactants. They was evaluated through several parameters : solubility, Krafft point, Critical Micellar Concentration, static and dynamic surface tension, foaming power, wetting time and zeta potential; and compared to the predictive models : Hydrophilic/Lipophilic Balance (HLB) and partition coefficient octanol/water (log P). The toxicity of these new surfactants was measured through in vitro ocular irritation (Red Blood Cell test) and the ultimate biodegradation
Gilles, Laure. « Découverte et synthèse chimique d'odorants par des technologies innovantes ». Electronic Thesis or Diss., Université Côte d'Azur, 2022. http://www.theses.fr/2022COAZ4100.
Texte intégralThe perfumery industry in under constant pressure from national and international regulatory bodies as well and the demands of consumers to produce novel and safe organoleptic molecules via methods which are both durable and innovative. This constant drive for innovation pushes researchers towards diverse domains of the plant kingdom which contains numerous complex natural substances (CNS). At present these natural products are a source of ingredients, however, they are equally a source of inspiration for the chemist who may identify structures of interest to be synthesised with a high degree of control (chirality, quantity, quality, consistency), as well as structural analogues to provide an improvement of the olfactory properties (notes, intensity).This manuscript presents an extended analysis of the distillate of a concrete of the plant Ocimum gratissimum via GC-O complemented with GC-MS analysis. This study has also enlighted the chemical composition of the extract, characterisation of the poorly described (E)-methyl cinnamate chemotype, olfactory evaluation by a master perfumer and the identification of the principal olfactive compounds. This work simultaneously explores multistep asymmetric synthetic strategies in the aim of obtaining the different enantiomers of vetispira-2(11),6-dien-14-al. This compound is known to be an important component of agar wood essential oil and largely responsible for its particular odour. Currently no syntheses of this compound have been published. An FeCl3 catalysed acetylation of α,β-unsaturated compounds was optimised and applied to the synthesis of 24 different heterocyclic spirocycles, which are to be submitted to a master perfumer for the evaluation of their notes and olfactory interest
Livres sur le sujet "Produits biologiques – synthèse chimique"
Carbohydrates-Synthetic Methods and Applications in Medicinal Chemistry. VCH Publishing, 1993.
Trouver le texte intégralScheuer, Paul J. Bioorganic Marine Chemistry. Springer, 1991.
Trouver le texte intégralScheuer, Paul J. Bioorganic Marine Chemistry. Springer, 1988.
Trouver le texte intégralScheuer, Paul J. Bioorganic Marine Chemistry. Springer, 1987.
Trouver le texte intégralScheuer, Paul J. Bioorganic Marine Chemistry. Springer, 1989.
Trouver le texte intégralChapitres de livres sur le sujet "Produits biologiques – synthèse chimique"
FAGES, François, et Franck MOLINA. « La cellule, un calculateur analogique chimique ». Dans Approches symboliques de la modélisation et de l’analyse des systèmes biologiques, 255–74. ISTE Group, 2022. http://dx.doi.org/10.51926/iste.9029.ch7.
Texte intégralActes de conférences sur le sujet "Produits biologiques – synthèse chimique"
Magnaudeix, Amandine, et Eric Champion. « Développement de céramiques pour l'ingénierie tissulaire osseuse : de la synthèse de matériaux à l’évaluation biologique ». Dans Les journées de l'interdisciplinarité 2022. Limoges : Université de Limoges, 2022. http://dx.doi.org/10.25965/lji.301.
Texte intégralRapports d'organisations sur le sujet "Produits biologiques – synthèse chimique"
Campbell, Bryan, et Michel Magnan. Vers la nouvelle bioéconomie : La biofabrication comme initiative stratégique de développement économique pour le Québec. CIRANO, septembre 2022. http://dx.doi.org/10.54932/jqgh2110.
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