Articles de revues : « Pregnancy Complications »

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Kochar Kaur, Kulvinder. « Endometriosis and Pregnancy - Associated Complications ». Open Access Journal of Gynecology 3, n^o 3 (2018) : 1–2. http://dx.doi.org/10.23880/oajg-16000164.

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Murugaboopathi, Sindhuja, et Hephzibah Kirubamani. « Awareness of Complications of First Trimester Pregnancy ». Indian Journal of Obstetrics and Gynecology 7, n^o 4 (P-2) (2019) : 627–31. http://dx.doi.org/10.21088/ijog.2321.1636.7419.9.

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Aslam Ahsan, Dr Muhammad, et Dr Muhammad Rafique Cheema. « PREGNANCY ; THROMBOEMBOLIC COMPLICATIONS ». PROFESSIONAL MEDICAL JOURNAL 23, n^o 03 (1 mars 2016) : 284–87. http://dx.doi.org/10.17957/tpmj/16.2952.

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NYBERG, DAVID A., LAURENCE A. MACK, FAYE C. LAlNG et R. BROOKE JEFFREY. « Early Pregnancy Complications ». Obstetrical & ; Gynecological Survey 44, n^o 2 (février 1989) : 108–11. http://dx.doi.org/10.1097/00006254-198902000-00005.

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Gnanasambanthan, Sai, et Shree Datta. « Early pregnancy complications ». Obstetrics, Gynaecology & ; Reproductive Medicine 29, n^o 2 (février 2019) : 29–35. http://dx.doi.org/10.1016/j.ogrm.2018.12.011.

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Taghiyeva, A., L. Kiliç, M. Cagan, E. C. Bolek, G. K. Yardimci, O. Karadag, O. Ozyuncu et Ş. A. Bilgen. « POS0813 FERTILITY AND PREGNANCY OUTCOMES IN TAKAYASU’S ARTERITIS ». Annals of the Rheumatic Diseases 80, Suppl 1 (19 mai 2021) : 659–60. http://dx.doi.org/10.1136/annrheumdis-2021-eular.3231.

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Background:Takayasu’s arteritis (TA) is commonly seen in women of childbearing ages; therefore, reproductive health of TA patients is an important issue.Objectives:We aimed to evaluate the fertility and pregnancy (PG) outcomes of TA patients before and after diagnosis.Methods:In the prospective database of the Hacettepe University Vasculitis Research Centre (HUVAC), 202 TA patients (female =184) meeting the 1990 ACR criteria were registered by the end of February 2020. 120 patients who could be reached out gynaecological records and marriage status, were included in the study. We identified 233 PG in 82 of included these 120 TA patients (Figure 1). Demographic and clinical features, comorbidities, distribution of vascular involvement, obstetrical histories and outcomes were retrospectively evaluated. Patients were classified according to a novel proposed disease clusters (C1: Abdominal Predominant, C2: Aortic Arch Predominant, C3: Focal Disease) using the defined decision tree.Results:12 of 96 (12.5%) married TA patients had infertility being defined as not being able to get pregnant after one year (or longer) of unprotected sex. 20 (16.7%) women had menopause before the age of 45, being defined as early menopause (EM). Compared to normal population, infertility (12.5% vs. 8.1%) and EM ratios (16.7% vs. 7.6%) seem to be increased in TA patients. (1, 2)200 PG had occurred before TA diagnosis (bTA) in 71 women, and 33 PG were observed after TA diagnosis (aTA) diagnosis in 19 women (two patients diagnosed during PG). According to novel disease subsets, aTA patients classified into C1 (n=3; 15.7%), C2 (n=9; 47.3%) and C3 (n=6; 31.5%). One patient could not be classified.GHT was seen in 4 (12.1%) patients being the most frequent maternal complication in aTA group. Most common fetal complications were prematurity, IUGR and LBW in both groups (Table 1). Even fetal complications were more frequent in aTA group, it was not statistically significant [11 (33.3%) vs. 43 (21.5%), p=0.18 respectively]. However, maternal complications were significantly more common in aTA group [22 (11.0%) vs. 8 (24.2%), p=0.048]. There was no difference for the obstetrical outcomes in terms of novel TA classification.Conclusion:This study showed increased infertility and EM ratios in TA patients. PG of aTA had more complications in terms of maternal complications. Fetal complications were more frequent in PG of aTA but not statistically significant. Larger cohort data is required.References:[1]doi:10.1017/s0021932017000244.[2]doi:10.1016/j.maturitas.2019.03.008.PregnanciespBefore TA (n=200)After TA (n=33)Number of Patients7119NPAge at TA diagnosis, years mean (SD)38.2 (13.1)24.0 (6.6)Age at first pregnancy21.7 (5.0)27.6 (5.0)Comorbidities/CV Risk factors n(%)n (%)p- Smoking22 (31)3 (15.8)>0.05- Dyslipidemia14 (19.7)1 (5.3)- Hypertension29 (40.8)9 (47.4)- Diabetes mellitus8 (11.3)0 (0)Maternal Complicationsn (%)Numbers of pregnancies with any maternal complications22 (11.0)8 (24.2)0.048- Gestational hypertension6 (3.0)4 (12,1)NP- PROM6 (3.0)1 (3.0)- GDM0 (0)0 (0)- Bleeding (Antepartum/postpatum)6 (3.0)2 (6.1)- Preeclampsia0 (0.0)0 (0.0)- İnfection5 (2.5)1 (3.0)- Placenta previa0 (0)1 (3.0)Fetal Complicationsn (%)pNumbers of pregnancies with any fetal complications43 (21.5)11 (33.3)0.180- LBW16 (8.0)6 (18.2)NP- IUGR20 (1.0)5 (15.2)- Preterm birth13 (6.5)7 (21.2)- CNS complications2 (1.0)1 (3.0)- Cardiovascular complications3 (1.5)0 (0)- RDS_BPD4 (2.0)0 (0)- NICU admission12 (6.0)1 (3.0)- Other5 (2.5)0 (0)- Neonatal death5 (2.5)0 (0)- Retinopathy of prematurity1 (0.5)0 (0)- Stillbirth7 (3.5)0 (0)Deliveryn (%)PVaginal delivery128 (64)6 (18.2)<0.001Cesarean24 (12)13 (39.4)<0.001Spontaneous abortus21 (10.5)7 (21.2)0.088Termination of pregnancy18 (9.0)7 (21.2)0.061Abbreviations: BPD: Bronchopulmonary dysplasia, CNS: Central nervous system, GDM: Gestational diabetes mellitus, IUGR: Intrauterin growth restriction, LBW: Low birth weight, NICU: Neonatal Intensive Care Unit, NP: Not performed PROM: Premature rupture of membranes, RDS: Respiratory distress syndromeDisclosure of Interests:None declared

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VK, Sita, et N. Hephzibah Kirubamani. « Awareness on Complications of Fever in Early Pregnancy ». Indian Journal of Obstetrics and Gynecology 7, n^o 3 (P-2) (2019) : 487–93. http://dx.doi.org/10.21088/ijog.2321.1636.7319.20.

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Junagam, Sreeman N., et Balu Jatthavath. « EVALUATION OF LIVER ENZYMES IN PREGNANCY WITH COMPLICATIONS ». International Journal of Integrative Medical Sciences 5, n^o 6 (5 juillet 2018) : 659–62. http://dx.doi.org/10.16965/ijims.2018.119.

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Middeldorp, Saskia. « Anticoagulation in pregnancy complications ». Hematology 2014, n^o 1 (5 décembre 2014) : 393–99. http://dx.doi.org/10.1182/asheducation-2014.1.393.

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Abstract Women with acquired and inherited thrombophilia are thought to be at increased risk for pregnancy complications, including recurrent pregnancy loss and, depending on the type of thrombophilia, severe preeclampsia. This review discusses the associations between the types of thrombophilia and types of complications, as well as the currently available clinical trial evidence regarding the use of aspirin and heparin to prevent these pregnancy complications. In women with antiphospholipid syndrome, guidelines recommend prescribing aspirin and heparin to women with recurrent miscarriage. The same regimen is suggested for late pregnancy complications by some, but not all, experts. Aspirin or low-molecular-weight heparin to improve pregnancy outcome in women with unexplained recurrent miscarriage has no benefit and should not be prescribed. Whether anticoagulant therapy prevents recurrent miscarriage in women with inherited thrombophilia or in women with severe pregnancy complications remains controversial because of inconsistent results from trials. Aspirin modestly decreases the risk of severe preeclampsia in women at high risk.

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Kashif, Uzma, Nadia Riaz, Swapna Percholli Ramasubramanian et David Iles. « Urogynaecological complications in pregnancy ». Obstetrics, Gynaecology & ; Reproductive Medicine 31, n^o 2 (février 2021) : 42–47. http://dx.doi.org/10.1016/j.ogrm.2020.12.004.

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Gongora, Maria, et Nanette Wenger. « Cardiovascular Complications of Pregnancy ». International Journal of Molecular Sciences 16, n^o 10 (9 octobre 2015) : 23905–28. http://dx.doi.org/10.3390/ijms161023905.

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Asaad MA Abdallah. « Thalassemia and pregnancy complications ». World Journal of Advanced Research and Reviews 14, n^o 1 (30 avril 2022) : 363–67. http://dx.doi.org/10.30574/wjarr.2022.14.1.0284.

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Thalassemia is a blood disorder passed down through families (inherited) in which the body makes an abnormal form or inadequate amount of hemoglobin. Hemoglobin is the protein in red blood cells that carries oxygen. The disorder results in large numbers of red blood cells being destroyed, which leads to anemia. This abnormal alpha- to beta-chain ratio causes the unpaired chains to precipitate and causes destruction of red blood cell precursors in the bone marrow (ineffective erythropoiesis) and circulation (hemolysis). Affected individuals with thalassemia have variable degrees of anemia and extramedullary hematopoiesis, which in turn can cause bone changes, impaired growth, and iron overload. Recurrent pregnancy loss (RPL), also known as recurrent miscarriages, is defined by the consecutive loss of two or more pregnancies with the same partner and having no more than one living child. Objective of the current review was to determine the maternal and fetal outcomes of women complicated with thalassemia .Conclusion: There are many changes as complications of thalassemia and the stress of pregnancy can make the symptoms of thalassemia worse . pregnancy in thalassemia should be considered high risk and should always be preceded by a complete preconception assessment.

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Maestas, R. R. « Medical Complications During Pregnancy ». Journal of the American Board of Family Medicine 13, n^o 3 (1 mai 2000) : 231. http://dx.doi.org/10.3122/15572625-13-3-231b.

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Ray, Joel G. « Medical Complications during Pregnancy ». Annals of Internal Medicine 132, n^o 6 (21 mars 2000) : 512. http://dx.doi.org/10.7326/0003-4819-132-6-200003210-00025.

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Simcox, Louise, Laura Ormesher, Clare Tower et Ian Greer. « Thrombophilia and Pregnancy Complications ». International Journal of Molecular Sciences 16, n^o 12 (30 novembre 2015) : 28418–28. http://dx.doi.org/10.3390/ijms161226104.

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PERRY, KENNETH G. « HEMATOLOGIC COMPLICATIONS OF PREGNANCY ». Clinical Obstetrics and Gynecology 38, n^o 3 (septembre 1995) : 441. http://dx.doi.org/10.1097/00003081-199509000-00003.

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&NA;. « Hematologic Complications of Pregnancy ». Clinical Obstetrics and Gynecology 38, n^o 3 (septembre 1995) : 573–74. http://dx.doi.org/10.1097/00003081-199509000-00015.

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Vormittag, R., et I. Pabinger. « Thrombophilia and pregnancy complications ». Hämostaseologie 26, n^o 01 (2006) : 59–62. http://dx.doi.org/10.1055/s-0037-1616879.

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ZusammenfassungVenöse Thrombosen und Lungenembolien sind die führende Ursache schwangerschaftsbedingter Morbidität und Mortalität. Frauen mit Thrombophilie haben ein erhöhtes Thromboserisiko während der Schwangerschaft und des Puerperiums. Bei Frauen mit hereditärem Thromboserisikofaktor wurde ein relatives Risiko von 3,4 bis 15,2 für eine schwangerschaftsassoziierte Thrombose festgestellt. Frauen mit vorangegangener Thrombose haben während der Schwangerschaft ein 3,5-mal höheres Rezidivrisiko als sonst.Die Daten über eine Assoziation zwischen Thrombophilie und Aborten oder Präeklampsie sind widersprüchlich. Abgesehen von einer etablierten Risikoerhöhung für Aborte durch Antiphospholipid-Antikörper gibt es Hinweise für eine Bedeutung des Antithrombinmangels, der Hyperhomozysteinämie, des Faktor V Leiden, der Prothrombin- G20210A-Variation und des Protein-S-Mangels. Ein Zusammenhang zwischen Thrombophilie und Präeklampsie ist weniger gut belegt. Die Zahl verfügbarer, prospektiver Studien ist begrenzt, und diese fanden keine Risikoerhöhung in einem unselektionierten Patientengut mit Thromboserisikofaktor. Verfügbar sind Daten einer kontrollierten Studie über die Prävention eines Schwangerschaftsverlusts mittels niedermolekularem Heparin (NMH), welches eine starke positive Wirkung zeigte. Thrombophilie-Screening mag bei Frauen mit Aborten, insbesondere ab der 10 Schwangerschaftswoche, angezeigt sein und eine Prophylaxe mit NMH sollte bei jenen Frauen überlegt werden, bei denen eine Thrombophilie festgestellt wird. Weitere prospektive Studien und kontrollierte Interventionsstudien werden dringend benötigt.

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Lapinsky, Stephen E. « Cardiopulmonary complications of pregnancy ». Critical Care Medicine 33, n^o 7 (juillet 2005) : 1616–22. http://dx.doi.org/10.1097/01.ccm.0000170189.72840.14.

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Sheth, Bhavna P., et William F. Mieler. « Ocular complications of pregnancy ». Current Opinion in Ophthalmology 12, n^o 6 (décembre 2001) : 455–63. http://dx.doi.org/10.1097/00055735-200112000-00011.

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Graves, Cornelia R., et Stacy F. Davis. « Cardiovascular Complications in Pregnancy ». Circulation 137, n^o 12 (20 mars 2018) : 1213–15. http://dx.doi.org/10.1161/circulationaha.117.031592.

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COOPER, JOHN K. « First Trimester Pregnancy Complications ». Clinical Obstetrics and Gynecology 50, n^o 1 (mars 2007) : 1. http://dx.doi.org/10.1097/grf.0b013e318032ff14.

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Townsley, Danielle M. « Hematologic Complications of Pregnancy ». Seminars in Hematology 50, n^o 3 (juillet 2013) : 222–31. http://dx.doi.org/10.1053/j.seminhematol.2013.06.004.

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Aharon, Anat, et Benjamin Brenner. « Microparticles and pregnancy complications ». Thrombosis Research 127 (février 2011) : S67—S71. http://dx.doi.org/10.1016/s0049-3848(11)70019-6.

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Newfield, Emily. « Third-Trimester Pregnancy Complications ». Primary Care : Clinics in Office Practice 39, n^o 1 (mars 2012) : 95–113. http://dx.doi.org/10.1016/j.pop.2011.11.005.

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Taylor-Robinson, David. « Non-Pregnancy Complications Introduction ». International Journal of STD & ; AIDS 8, n^o 1_suppl (décembre 1997) : 17–19. http://dx.doi.org/10.1258/0956462971919291.

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Brenner, B. « Thrombophilia and Pregnancy Complications ». Pathophysiology of Haemostasis and Thrombosis 35, n^o 1-2 (2006) : 28–35. http://dx.doi.org/10.1159/000093540.

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Graham, Anna, Sangeetha Devarajan et Shreelata Datta. « Complications in early pregnancy ». Obstetrics, Gynaecology & ; Reproductive Medicine 25, n^o 1 (janvier 2015) : 1–5. http://dx.doi.org/10.1016/j.ogrm.2014.10.009.

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Meguerdichian, David. « Complications in Late Pregnancy ». Emergency Medicine Clinics of North America 30, n^o 4 (novembre 2012) : 919–36. http://dx.doi.org/10.1016/j.emc.2012.08.002.

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Pontius, Elizabeth, et Julie T. Vieth. « Complications in Early Pregnancy ». Emergency Medicine Clinics of North America 37, n^o 2 (mai 2019) : 219–37. http://dx.doi.org/10.1016/j.emc.2019.01.004.

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Bódis, L., Z. Szupera, M. Pierantozzi, F. Bandini, K. Sas, L. Kovács, L. Vécsei et I. Bódis. « Neurological complications of pregnancy ». Journal of the Neurological Sciences 153, n^o 2 (janvier 1998) : 279–93. http://dx.doi.org/10.1016/s0022-510x(97)00297-9.

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Mighty, Hugh E., et Jenifer O. Fahey. « Obesity and pregnancy complications ». Current Diabetes Reports 7, n^o 4 (11 juillet 2007) : 289–94. http://dx.doi.org/10.1007/s11892-007-0046-y.

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Yassin, Ahmed S., Effi Eyong et P. Turner. « Orthopaedic complications of pregnancy ». Obstetrician & ; Gynaecologist 2, n^o 2 (avril 2000) : 41–44. http://dx.doi.org/10.1576/toag.2000.2.2.41.

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Devinsky, Orrin, Edward Feldmann et Brian Hainline. « Neurologic Complications of Pregnancy ». Journal of Neuro-Ophthalmology 16, n^o 1 (mars 1996) : 76. http://dx.doi.org/10.1097/00041327-199603000-00097.

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Ie, Susanti, Edmundo R. Rubio, Brent Alper et Harold M. Szerlip. « Respiratory Complications of Pregnancy ». Obstetrical and Gynecological Survey 57, n^o 1 (janvier 2002) : 39–46. http://dx.doi.org/10.1097/00006254-200201000-00022.

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Frye, Donna, Steven L. Clark, Dawn Piacenza et Gina Shay-Zapien. « Pulmonary Complications in Pregnancy ». Journal of Perinatal & ; Neonatal Nursing 25, n^o 3 (2011) : 235–44. http://dx.doi.org/10.1097/jpn.0b013e3182230e25.

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Grabowski, Eric, Margaretta Hellgren, Gili Kenet, Patricia Massicotte, Marilyn Manco-Johnson, Prasad Mathew, Wolfgang Muntean, Nicole Schlegel, Ulrike Nowak-Göttl et Benjamin Brenner. « Thrombophilia and pregnancy complications ». Thrombosis and Haemostasis 92, n^o 10 (2004) : 678–81. http://dx.doi.org/10.1160/th04-02-0096.

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SummaryThe implications of currently available data on the association of gestational vascular complications with thrombophilia are presented in this consensus report. Screening is recommended for women with the following previous complications: fetal loss including three or more first trimester loss, two or more second trimester loss, or any stillbirth; early, severe or recurrent preeclampsia and severe intrauterine growth restriction. Maternal antithrombotic therapy is currently evaluated in women with thrombophilia and previous complications.On behalf of the Scientific Subcommittee on Perinatal and Pediatric Hemostasis and Working Group on Women’s health Issues and Standardization Committee of the International Society of Thrombosis and Hemostasis.

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Homburg, Roy. « Pregnancy complications in PCOS ». Best Practice & ; Research Clinical Endocrinology & ; Metabolism 20, n^o 2 (juin 2006) : 281–92. http://dx.doi.org/10.1016/j.beem.2006.03.009.

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Kujovich, Jody L. « Thrombophilia and pregnancy complications ». American Journal of Obstetrics and Gynecology 191, n^o 2 (août 2004) : 412–24. http://dx.doi.org/10.1016/j.ajog.2004.03.001.

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Doherty, Anne, Kelsey McLaughlin et John C. Kingdom. « Hemodynamic Complications in Pregnancy ». Clinics in Perinatology 47, n^o 3 (septembre 2020) : 653–70. http://dx.doi.org/10.1016/j.clp.2020.05.014.

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Pereira, Adriana, et Bruce P. Krieger. « Pulmonary complications of pregnancy ». Clinics in Chest Medicine 25, n^o 2 (juin 2004) : 299–310. http://dx.doi.org/10.1016/j.ccm.2004.01.010.

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Cuero, Mauricio Ruiz, et Panayiotis N. Varelas. « Neurologic Complications in Pregnancy ». Critical Care Clinics 32, n^o 1 (janvier 2016) : 43–59. http://dx.doi.org/10.1016/j.ccc.2015.08.002.

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Hoefnagel, Amie, Albert Yu et Anna Kaminski. « Anesthetic Complications in Pregnancy ». Critical Care Clinics 32, n^o 1 (janvier 2016) : 1–28. http://dx.doi.org/10.1016/j.ccc.2015.08.009.

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Carr, Stephen R. « Medical Complications During Pregnancy ». JAMA : The Journal of the American Medical Association 274, n^o 15 (18 octobre 1995) : 1247. http://dx.doi.org/10.1001/jama.1995.03530150071041.

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Burger, JoAnne, Sarah McCue Horwitz, Brian W. C. Forsyth, John M. Leventhal et Philip J. Leaf. « Psychological Sequelae of Medical Complications During Pregnancy ». Pediatrics 91, n^o 3 (1 mars 1993) : 566–71. http://dx.doi.org/10.1542/peds.91.3.566.

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To determine whether mothers with complicated pregnancies are at increased risk of postpartum depression and whether their children are at increased risk of being perceived as vulnerable, the investigators conducted an interview survey of mothers of 1095 children aged 4 to 8 in a community-based sample of primary care pediatric practices. The offspring were viewed as vulnerable by 17% of the women with severe pregnancy complications and 9% of the women without pregnancy complications (relative risk = 1.88; 95% confidence interval = 1.11, 2.63). Women with a severe complication of pregnancy were significantly more likely to report postpartum depression than those without a complication (27% vs 11%; relative risk = 2.45; 95% confidence interval = 1.55, 3.01). These relationships persisted after adjustment for prematurity, neonatal hospitalization, and demographic factors. It is concluded that pregnancy complications may place a woman at increased risk of postpartum depression and may have important effects on a mother's long-term perceptions of her child's vulnerability to illness.

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., Akansha, et Nagajan Bhadarka. « Incidence of early pregnancy complications, management protocols and its outcome in patients at Gujarat Adani Institute of Medical Science, Bhuj, Kutch, Gujarat, India ». International Journal of Reproduction, Contraception, Obstetrics and Gynecology 6, n^o 9 (28 août 2017) : 3837. http://dx.doi.org/10.18203/2320-1770.ijrcog20173667.

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Background: Early Pregnancy Complications can cause significant morbidity and mortality. Pregnant women an present with h/o amenorrhea, abdominal pain, vaginal bleeding or incidental scan finding of missed abortion, ectopic pregnancy and vesicular mole, features of hypermesis gravidorum like fatigue, nausea, vomiting, dryness and diminished urine output. The objective of present study was to analyze the incidence of various early pregnancy complications, assess the protocols for diagnosing these complications and their management.Methods: Present study was conducted at the Department of Obstetrics and Gynecology, Gujarat Adani Institute of Medical Science, Bhuj, Kutch, Gujarat. All the women with first trimester pregnancy with different complications were included in this study while those women with uneventful first trimester were excluded. The inducted women were registered on pre-designed proforma. Studied variables including demographic details, gestational period, type of complications, risk factors, treatment and outcome.Results: Out of 740 total admissions 439 abortions of which incomplete abortion was 262, missed abortions were 132, threatened abortion 42 and 3 cases of septic abortion, ectopic pregnancy 154, molar pregnancy33, hyperemesis 31. There were about 63 cases of non-pregnancy related complication reported during early pregnancy like 31 with UTI, 9 with renal colic, 2 cases of appendicitis, four cases of asymptomatic cholelithiasis, 2 cases of hepatitis, 5 cases of ovarian cyst complicating pregnancy, 2 cases of ovarian torsion. Their mean age was 30.8+6.8 years.Conclusions: Study was successful in creating a confidence among trainees when following the recommended protocols as well as delivering clinical benefits to the hospital, patients and staff. Early gynecological consultation and bedside ultrasound scanning within the emergency department were key requirements for any emergency concerns.

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Tripathi, M., et R. Shrestha. « Pregnancy Outcome of Twin Pregnancy at Gandaki Medical College Teaching Hospital, Pokhara, Nepal ». Journal of Gandaki Medical College-Nepal 11, n^o 02 (31 décembre 2018) : 1–4. http://dx.doi.org/10.3126/jgmcn.v11i02.22898.

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Objectives: To evaluate maternal and neonatal complications and pregnancy outcomes of twin pregnancies. Methods: The cross sectional study was conducted using retrospective data on the twin pregnancies with more than 28 weeks of gestational age. The study used data over a period of five years, from March 10, 2010 to March 9, 2015 in the Department of Obstetrics and Gynecology, GMC Teaching Hospital Pokhara. Results: Of the 50 twin pregnancies, the most common maternal complication was preterm delivery (40%). Other maternal complications were anemia (36%), pregnancy induced hypertension (14%), premature rupture of membranes (14%), postpartum hemorrhage (12%) and antepartum hemorrhage (6%). Median gestational age at delivery was 37 weeks. Most common route of delivery was cesarean section (66%). Most common neonatal complication was low birth weight (48%) births first twin and second twin 56%. Conclusion: Twin pregnancy has high maternal and neonatal complications, especially preterm delivery that increases the risk of significant neonatal morbidity and mortality.

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Andraweera, Prabha H., Zohra S. Lassi, Maleesa M. Pathirana, Michelle D. Plummer, Gus A. Dekker, Claire T. Roberts et Margaret A. Arstall. « Pregnancy complications and cardiovascular disease risk perception : A qualitative study ». PLOS ONE 17, n^o 7 (21 juillet 2022) : e0271722. http://dx.doi.org/10.1371/journal.pone.0271722.

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Objectives We aimed to assess women’s perceptions on the long-term risks for cardiovascular disease (CVD) after major pregnancy complications. Methods Women who experienced major pregnancy complications and those who experienced uncomplicated pregnancies were invited to participate in a qualitative study. Focus group discussions (FGDs) and self-administered questionnaires were used to explore: The knowledge of long-term sequelae after experiencing a major pregnancy complication; Importance of education on heart health; The practicality of referral to a clinic after pregnancy complications; Willingness for regular postpartum clinic visits after pregnancy complications. A thematic qualitative analysis was undertaken. Results 26 women participated in four FGDs. The majority of women did not know of the association between major pregnancy complications and CVD. The main views expressed were: Women who experience pregnancy complications should receive education on improving heart health; An appointment for the first CVD risk screening visit needs to be made prior to discharge from the delivery suite; Women will benefit by having the option to select between a hospital and a general-practitioner based model of follow up. Conclusions These views are important in developing postpartum strategies to reduce CVD risk among women who experience pregnancy complications.

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Lantsman, Taliya, Brandon-Luke Seagle, Junhua Yang, Daniel J. Margul, Jeanmarie Thorne-Spencer, Emily S. Miller, Masha Kocherginsky et Shohreh Shahabi. « Association between Cervical Dysplasia and Adverse Pregnancy Outcomes ». American Journal of Perinatology 37, n^o 09 (5 juin 2019) : 947–54. http://dx.doi.org/10.1055/s-0039-1692183.

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Objective The aim of this study was to determine if cervical dysplasia during pregnancy is associated with pregnancy complications, including preterm delivery and pre-eclampsia. Study Design A retrospective cohort analyses was performed with propensity-score matching to compare complication rates between pregnant women without history of abnormal cervical cancer screening and pregnant women referred for cervical dysplasia assessment to colposcopy clinic. A composite outcome of pregnancy complications included intra-amniotic infection, preterm premature rupture of membranes, pre-eclampsia, preterm delivery, low birth weight, oligohydramnios, and intrauterine fetal demise. Complication rates were compared between women with and without cervical dysplasia using logistic regression models. Results Overall cohort included 2,814 women, 279 of whom attended colposcopy clinic for cervical dysplasia assessment. Propensity score–matched cohort included 1,459 women, 274 of whom attended colposcopy clinic. Composite complications of pregnancy rates were not significantly different between control and colposcopy groups in both cohorts (25.3% and 29.0%, P = 0.20; 26.5% and 29.3%, P = 0.45). Dysplasia was not associated with composite pregnancy complications in overall and matched cohorts (odds ratio [OR] = 1.09, 95% confidence interval [CI]: 0.77–1.56) and (OR = 1.03, 95% CI: 0.72–1.49). When cervical dysplasia was determined on biopsy or colposcopy, dysplasia was not associated with complications in the overall and matched cohorts. Conclusion Biopsy and/or colposcopy determined cervical dysplasia during pregnancy was not associated with pregnancy complications.

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Kornacki, Jakub, Paweł Gutaj, Anastasia Kalantarova, Rafał Sibiak, Maurycy Jankowski et Ewa Wender-Ozegowska. « Endothelial Dysfunction in Pregnancy Complications ». Biomedicines 9, n^o 12 (24 novembre 2021) : 1756. http://dx.doi.org/10.3390/biomedicines9121756.

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The endothelium, which constitutes the inner layer of blood vessels and lymphatic structures, plays an important role in various physiological functions. Alterations in structure, integrity and function of the endothelial layer during pregnancy have been associated with numerous gestational complications, including clinically significant disorders, such as preeclampsia, fetal growth restriction, and diabetes. While numerous experimental studies have focused on establishing the role of endothelial dysfunction in pathophysiology of these gestational complications, their mechanisms remain unknown. Numerous biomarkers of endothelial dysfunction have been proposed, together with the mechanisms by which they relate to individual gestational complications. However, more studies are required to determine clinically relevant markers specific to a gestational complication of interest, as currently most of them present a significant overlap. Although the independent diagnostic value of such markers remains to be insufficient for implementation in standard clinical practice at the moment, inclusion of certain markers in predictive multifactorial models can improve their prognostic value. The future of the research in this field lies in the fine tuning of the clinical markers to be used, as well as identifying possible therapeutic techniques to prevent or reverse endothelial damage.

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