Articles de revues : « Pathology registers »

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Svensson, Magnus, David Bergman, Ola Olén, Pär Myrelid, Johan Bohr, Anna Wickbom, Hamed Khalili, Andreas Münch, Jonas Halfvarson et Jonas F. Ludvigsson. « Validating microscopic colitis (MC) in Swedish pathology registers ». Scandinavian Journal of Gastroenterology 53, n^o 12 (2 décembre 2018) : 1469–75. http://dx.doi.org/10.1080/00365521.2018.1543446.

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Svantesson, Eleonor, Eric Hamrin Senorski, Angelo Baldari, Olufemi R. Ayeni, Lars Engebretsen, Francesco Franceschi, Jon Karlsson et Kristian Samuelsson. « Factors associated with additional anterior cruciate ligament reconstruction and register comparison : a systematic review on the Scandinavian knee ligament registers ». British Journal of Sports Medicine 53, n^o 7 (17 juillet 2018) : 418–25. http://dx.doi.org/10.1136/bjsports-2017-098192.

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ObjectiveTo present an overview of the Scandinavian knee ligament registers with regard to factors associated with additional ACL reconstruction, and studies comparing the Scandinavian registers with other knee ligament registers.DesignSystematic review.Data sourcesFour electronic databases: PubMed, EMBASE, the Cochrane Library and AMED were searched, and 157 studies were identified. Two reviewers independently screened titles, abstracts and full-text studies for eligibility. A modified version of the Downs and Black checklist was applied for quality appraisal.Eligibility criteria for selecting studiesEligible studies were those published since the establishment of the Scandinavian registers in 2004, which reported factors associated with additional ACL reconstruction and compared data from other registers.ResultsThirty-one studies met the inclusion criteria and generally displayed good reporting quality. Adolescent age (<20 years) was the most common factor associated with additional ACL reconstruction. The choice of hamstring tendon graft compared with patella tendon, transportal femoral tunnel drilling, smaller graft diameter and utilisation of suspensory fixation devices were associated with additional ACL reconstruction. Concomitant cartilage injury decreased the likelihood of additional ACL reconstruction. Patient sex alone did not influence the likelihood. The demographics of patients undergoing ACL reconstruction in the Scandinavian registers are comparable to registers in other geographical settings. However, there are differences in surgical factors including the presence of intra-articular pathology and graft choice.SummaryThe studies published from the Scandinavian registers in general have a high reporting quality when regarded as cohort studies. Several factors are associated with undergoing additional ACL reconstruction. The results from the registers may help facilitate treatment decisions.

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Cobb, P. G. W., et B. A. Henman. « The Indicative Registers of the Royal Society of Chemistry ». Journal of the Forensic Science Society 31, n^o 2 (avril 1991) : 191–95. http://dx.doi.org/10.1016/s0015-7368(91)73137-x.

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Bezruk, V. V., et YU Nechitaylo. « NEPHROLOGICAL PATHOLOGY IN SCHOOL AGE CHILDREN AS A COMPONENT OF THE RISK OFDEVEL OPMENT OF THE ARTERIAL HYPERTENSION ». Ukrainian Journal of Nephrology and Dialysis, n^o 1(41) (7 février 2014) : 5–7. http://dx.doi.org/10.31450/ukrjnd.1(41).2014.01.

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Calvo, F., C. Giralt et X. Carbonell. « Mental Health of Roofless and Squatter Population in North Catalonia ». European Psychiatry 41, S1 (avril 2017) : S676. http://dx.doi.org/10.1016/j.eurpsy.2017.01.1165.

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IntroductionHomelessness is a phenomenon, which is hard to limit, as it contemplates different situations including roofless and squatters.ObjectiveTo determine the presence of these homeless categories in the city of Girona and examine the prevalence of diagnosed mental pathology and its principal socio-demographic characteristics.MethodsTransversal, observational and analytic study of the population of roofless people and squatters. The registers of the outreach street work team, the local police and the public shelter were used in order to detect the cases and their basic socio-demographic characteristics. The clinical record of the mental health and addiction public network was accessed to determine their diagnosis.ResultsDuring the 6 years of registers, 781 cases of people in situation of roofless and squatters were detected. In total, 83.2% (n = 630) of the cases were men and 16.8% (n = 131) women. The average age was 44.8 (ED = 11.2) and no differences were found regarding gender (Men = 45.3, ED = 11.0 vs. Women = 42.9, ED = 12.2; t = 1.7, df = 405, P = 09). However differences were found regarding origin (Immigrants = 42.2 years, ED = 10.3 vs. Natives = 46.8 years, ED = 11.4; t = -4.2, df = 402, P < .001). A total of, 52.9% of the cases (n = 412) displayed diagnosed mental pathology and 15.8 (n = 123), dual pathology.ConclusionMental pathology is more prevalent among this typology of homeless people than in general population, as other studies prove.Disclosure of interestThe authors have not supplied their declaration of competing interest.

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Cohen, Andrea, Bridget Dolan et Nigel Eastman. « Research on the supervision registers : Inconsistencies in local research ethics committee responses ». Journal of Forensic Psychiatry 7, n^o 2 (septembre 1996) : 413–19. http://dx.doi.org/10.1080/09585189608415027.

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Cohen, Andrea, et Nigel Eastman. « A survey of the use of supervision registers in South Thames (West) Region ». Journal of Forensic Psychiatry 7, n^o 3 (décembre 1996) : 653–61. http://dx.doi.org/10.1080/09585189608415049.

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Lecturer, Estella Baker. « The introduction of supervision registers in England and Wales : A risk communications analysis ». Journal of Forensic Psychiatry 8, n^o 1 (mai 1997) : 15–35. http://dx.doi.org/10.1080/09585189708411992.

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Kitsera, N., et J. Shparyk. « Evaluation of occurence of cancer of the lung among young people in six regions of the western Ukraine ». Journal of Clinical Oncology 25, n^o 18_suppl (20 juin 2007) : 21188. http://dx.doi.org/10.1200/jco.2007.25.18_suppl.21188.

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21188 Background: Analysis of the cases of malignant lung tumors of young people (<34 yrs, born in 1963–2004) and diagnosed in 1997–2004 was made using the materials of the database of cancer registers of Volyn (V), Ivano-Frankivsk (IF), Lviv (L), Rivne (R), Ternopil (T) and Chernivtsi (C) regions. The population of young people <34 yrs of this region - 4.2 million/year. Results: Among 7541 cases of cancer in the six regions of the Western Ukraine malignant tumors of the lungs were diagnosed in 102 cases (1.4%). This pathology was registered in males in 57 cases, and in females in 45. The number of males with tumors of the lungs prevailed in V, IF, L, T. The number of young males and females with such pathology during the said period was the same - 11 cases in each gender group - in R. The youngest among the 102 individuals from the above said six regions were a boy aged 6 and a girl aged 16 from R. Combination with other tumors was observed in three females (C49, C53, C58) and one male (C81). In C among 766 cases of malignant tumors in young people <34 years lung cancer were detected in 5 (0.7%). Among 959 cases of cancer such tumors of the lungs were detected in 8 (0.8%) in V. Among the young people <34 years this pathology was detected in 14 (1.2%) in IF out of all 1156 cases of malignant tumors, in T - 947 tumor - 15 cases (1.6%). Among the six above regions in L there have been detected 2465 cases of malignant tumors, of which lung cancer were diagnosed in 38 - 1.5%. The highest frequency of occurrence of this pathology was registered in R (1.8%) - 22 cases in 1248 cases of malignant tumors. Conclusions: Fluctuation of frequency of this pathology in all these regions in various years during the investigated period had a wave-like character. As each of these regions is characterized by different geographic and climatic conditions, physical and chemical factors, exhausts of industrial enterprises, the study of frequency of malignant tumors in young people will permit to evaluated more objectively contribution of hereditary factor in the development of this pathology. The perspectives of further research in this field lie in the study of the role of genetic predisposition to the occurrence and development of malignant tumors in each patient, taking into account ecological zone of residence, occupational hazards and harmful habits. No significant financial relationships to disclose.

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Sayanna, Shengulwar, Muvva Uday Shankar et K. Ranjith Babu. « Incidence of thyroid diseases in a tertiary hospital : a retrospective study ». International Surgery Journal 6, n^o 4 (26 mars 2019) : 1254. http://dx.doi.org/10.18203/2349-2902.isj20191258.

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Background: Thyroid gland diseases are common in India, particularly hilly and tribal areas. The incidence of thyroid conditions, exact figure is not available but about 5 lakh cases come for Medical Treatment all over India. To study the prevalence of common thyroid diseases in the Sangareddy district area, which is near Hyderabad, particularly age & sex specific incidence.Methods: This is a retrospective study conducted at the Maheshwara Medical College and Hospital, Chitkul, Sangareddy district of Telangana State. The data was collected from the registers of General Surgery outpatient department, operation theatre, medical record section and cytology, histopathology registers of pathology department. A total number of 64 patients were included in this study who was admitted at this hospital during the period of 2 years, from January 2017 to December 2018. The data was analysed by proper statistical methods.Results: The study had shown that most common conditions in this area are benign diseases. The age group ranges 21-30 years, female are most vulnerable (37.51%). The pathological benign condition most common is nodular goiter 48.43%.Conclusions: The observations in this study made may be useful in future to diagnose the cases and advice regarding prevention of the disease.

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Guidoum, Mona, Hind Kherfi-Kadi, Ouahiba Benharkat-Boughaba, Aicha Djemaa-Bendjazia, Sihem Keghouche, Behnoush Abedi-Ardekani, Amina Azzouz, Yacine Kadi, Pierre Hainaut et Zihad Bouslama. « Patterns of Benign and Malignant Lesions of the Thyroid in Two Wilayahs of Northeastern Algeria ». Journal of Cancer Epidemiology 2015 (2015) : 1–5. http://dx.doi.org/10.1155/2015/849416.

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The aim of this study is to compare histological patterns and to estimate the burden of thyroid cancers in the two Wilayahs (departments) of El-Taref and Guelma in northeast of Algeria (total population 0.9 million), locally reputed as having different rates of endemic thyroid diseases and cancer. A retrospective analysis of central pathology registers and clinical records of patients with thyroid diseases, covering the period 2008–2012, was conducted. A total of 145 cases of thyroid cancers with histological confirmation were registered in the two Wilayahs during the period, with a female to male ratio of 5.9 : 1. Estimates of crude incidence rates suggested that thyroid cancers were twice as frequent in the Wilayah of Guelma compared to El-Taref (p<0.05) with a tendency to occur at a younger age in resident of the Wilayah of El-Taref. Diagnoses of thyroid adenoma were more frequent in the Wilayah of Guelma, whereas the prevalence of other thyroid lesions, including goitre, was similar in the two Wilayahs. This first descriptive study on geographic variations in thyroid cancer in Northern Africa suggests that significant differences may occur in relation with environmental and lifestyle exposures.

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Comeche, Jose M., Pablo Caballero, Ana Gutierrez-Hervas, Sofia García-Sanjuan, Iris Comino, Cesare Altavilla et Jose Tuells. « Enteral Nutrition in Patients with Inflammatory Bowel Disease. Systematic Review, Meta-Analysis, and Meta-Regression ». Nutrients 11, n^o 11 (4 novembre 2019) : 2657. http://dx.doi.org/10.3390/nu11112657.

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Inflammatory bowel disease (IBD) is a chronic disease mediated by the immune system and is characterized by inflammation of the gastrointestinal tract. One of the possible treatments for this pathology is a change in the type of diet, of which enteral nutrition (EN) is one. This study is to understand how the use of EN can affect the adult population diagnosed with IBD. We conducted a systematic review, meta-analysis, and a meta-regression. On the different databases (MEDLINE, Scopus, Cochrane, LILACS, CINAHL, WOS), we found 363 registers with an accuracy of 12% (44 registers). After a full-text review, only 30 research studies were selected for qualitative synthesis and 11 for meta-analysis and meta-regression. The variables used were Crohn’s disease activity index (CDAI), C-reactive protein (CRP), and erythrocyte sedimentation rate (ESR). EN has been shown to have efficacy for the treatment of Crohn’s disease and is compatible with other medicines. As for the CDAI or rates of remission, there were no differences between enteral and parenteral nutrition. Polymeric formulas have shown better results with respect to the CRP. The long-term treatment could dilute the good CDAI results that are obtained at the start of the EN treatment.

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Mokrysheva, N. G., E. V. Kovaleva et A. K. Eremkina. « Registries of parathyroid glands diseases in the Russian Federation ». Problems of Endocrinology 67, n^o 4 (16 septembre 2021) : 4–7. http://dx.doi.org/10.14341/probl12803.

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The most important and effective way to organize nationwide the healthcare, as well as monitoring and routing for patients with endocrine diseases, is the creation of an unified medical record (Endocard). The Endocard is also aimed at maximizing the opportunity for professionals and researchers on various scientific issues. Registries are the potential informational and analytical platform to achieve this goal. They include the basic information on the epidemiological and clinical features of the most severe diseases such as diabetes mellitus. Given the lack of large-scale epidemiological data on the parathyroid glands pathology — primary hyperparathyroidism and hypoparathyroidism — the registers of these diseases that collects a common dataset and clinician and patient reported outcomes are of particular interest.

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Yakushin, Sergey S., Natal’ya N. Nikulina et Yuliya V. Terekhovskaya. « Clinical Manifestations and Diagnosis of Pulmonary Embolism in Routine Clinical Practice : Data from the Ryazan Regional Vascular Center ». I.P. Pavlov Russian Medical Biological Herald 30, n^o 1 (31 mars 2022) : 51–62. http://dx.doi.org/10.17816/pavlovj85405.

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BACKGROUND: Data on the peculiarities of the clinical presentation and characteristics of pulmonary embolism (PE) and problems of its diagnosis in routine clinical practice (CP) are limited. Data obtained long ago are mostly described in terms of venous thromboembolism in general and practically do not include Russian patients with PE. The study was performed within the RusSIan REgistery of pulmoNAry embolism (SIRENA) register. AIM: To study the peculiarities of the clinical and demographic profile and diagnosis of PE in modern CP in comparison with the results of other PE registers. MATERIALS AND METHODS: In this registry-based study, medical records were analyzed to obtain information on the demographic profile, clinical presentation, and examination results of patients with PE (n = 107; age, 63 (5274) years; men, 39.3%) who received inpatient treatment in one of the Ryazan Regional Vascular centers. The study period was 13 months (20182019). RESULTS: The most common concomitant pathologies were arterial hypertension (70.1%), obesity (46.7%), and diabetes mellitus (17.8%). High- and moderate-risk factors were identified in 26.2% and 72.9% of the patients, respectively. Low-risk factors identified in 5.6% of the patients in different combinations did not have a single risk factor for PE development. Clinical manifestations included shortness of breath (93.5%), chest pain (43.0%), severe weakness (59.8%), tachycardia (29.0%), hypoxemia (27.1%), and unstable hemodynamics (18.7%). The most frequent electrocardiographic sign was a T-wave inversion in the right chest leads (52.3%). Right ventricle dysfunction was detected in 38.1% of the cases and elevation of troponin levels in 33.6%. According to the Pulmonary Embolism Severity Index scale, high- and very-high-risk cases accounted for 46.7% of the cases. According to the results of the integrated assessment of PE severity, 34.6% and 14.0% of the patients moved to the lower- and higher-risk classes, respectively. The proportion of moderate-risk cases increased from 23.4% to 62.6%, and the high- and very-high-risk cases reduced from 46.7% to 32.0%. CONCLUSION: The modern clinical picture of PE is characterized by a higher prevalence of concomitant pathology and reduction of the rates of traditional risk factors. There remain difficulties in PE diagnosis, which are associated with the concomitant pathology, absence of traditional risk factors, and non-specificity of the clinical manifestations and results of additional examinations.

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Buzzaccarini, Giovanni, Luis Alonso Pacheco, Amerigo Vitagliano, Sergio Haimovich, Vito Chiantera, Péter Török, Salvatore Giovanni Vitale, Antonio Simone Laganà et Jose Carugno. « Pain Management during Office Hysteroscopy : An Evidence-Based Approach ». Medicina 58, n^o 8 (20 août 2022) : 1132. http://dx.doi.org/10.3390/medicina58081132.

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Background and Objectives: Hysteroscopy is a reliable technique which is highly useful for the evaluation and management of intrauterine pathology. Recently, the widespread nature of in-office procedures without the need for anesthesia has been requesting validation of practical approach in order to reduce procedure-related pain. In this regard, we performed a comprehensive review of literature regarding pain management in office hysteroscopic procedures. Materials and Methods: MEDLINE, EMBASE, The Cochrane Library (Cochrane Database of Systematic Reviews, Cochrane Central Register of Controlled Trials, Cochrane Methodology Register), Global Health, Health Technology Assessment Database and Web of Science, other research registers (for example Clinical Trials database) were searched. We searched for all original articles regarding pain relief strategy during office hysteroscopy, without date restriction. Results have been collected and recommendations have been summarized according to the Appraisal of Guidelines for Research and Evaluation (AGREE) tool. Moreover, the strength of each recommendation was scored following the Grading of Recommendations Assessment (GRADE) system, in order to present the best available evidence. Results: Both pharmacological and non-pharmacological strategies for pain management are feasible and can be applied in office setting for hysteroscopic procedures. The selection of strategy should be modulated according to the characteristics of the patient and difficulty of the procedure. Conclusions: Accumulating evidence support the use of pharmacological and other pharmacological-free strategies for reducing pain during office hysteroscopy. Nevertheless, future research priorities should aim to identify the recommended approach (or combined approaches) according to the characteristics of the patient and difficulty of the procedure.

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Kashutina, Tatyana Antoninovna, et Vasiliy Nikolayevich Chuchin. « The daily rhythm of activity of corporal biologically active points of cattle in control, with chronic bronchopneumonia and castration ». Agrarian Scientific Journal, n^o 1 (27 janvier 2019) : 44–47. http://dx.doi.org/10.28983/asj.v0i1.692.

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Bioenergy studies have shown that daily rhythms of activity of corporate biologically active points of cattle in clinically healthy animals, with chronic bronchopneumonia and castration differ significantly. The current imbalance of life energy in internal organs of animals in accordance with the internal biological clock registers depending on the pathology in the vital points of the nearest part of the body in relation to the epicenter of the stress factor. So, in chronic bronchopneumonia, it is the canal of the lungs, and when castrated, it is the bladder. Biologically active points 52, 51, 10 - 17, 21, 24 and 97 were the most informative. According to the results of the experiment, “corridor of the norm” of life points biopotentials is approximately 9 – 10 µa. Test voltage up to 2 V was recorded in healthy and up to 3 V - in sick animals.

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Atanda, A. T. « Audit of Histopathology Reports for Breast Cancer in Aminu Kano Teaching Hospital ». West Africa Journal of Medicine 29, n^o 3 (1 janvier 2010) : 174–77. http://dx.doi.org/10.55891/wajm.v29i3.2.

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BACKGROUND The usefulness of histopathology reports is a function of the quality of information contained therein Thus there is need to establish minimum criteria to be met in reporting cases as a quality control mechanism OBJECTIVE To audit the quality of histopathology reports of mastectomy specimens received in the pathology laboratory of a Teaching Hospital METHODS Laboratory numbers of all cancer bearing mastectomy cases received in 10 years (1999–2008) were extracted from pathology reception registers and their accompanying original request cards were retrieved from archives From these cards relevant information meeting six set audit criteria and average turn around times were determined and analysed RESULTS One hundred and sixty-five mastectomy cases were received but archival retrieval was possible for only 134 (812%) cases The reports documented tumour size macroscopic resection margin histological tumour type histological grading lymphaticvascular invasion characterized by invasion of tumour cells into lymphatic vessels arteries or more importantly veins and microscopic resection margin These were documented in 50% 62% 92% 40% 12% and 64% of cases respectively Average turn around time was 158 days Only three (22%) of the reports met all the six criteria CONCLUSION This 10-year audit shows the lapses in our histopathology reports and the need for establishment of standard report formats as tools for quality assurance WAJM

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Essome, Henri, Thomas O. Egbe, Gregory E. Halle, Théophile N. Nana, Merlin Boten, Grace T. Tocki et Pascal Foumane. « Epidemiology of ectopic pregnancy at Laquintinie Douala hospital (Cameroon) : prevalence survey, clinical profile, therapeutic and transfusion issues ». International Journal of Reproduction, Contraception, Obstetrics and Gynecology 10, n^o 1 (26 décembre 2020) : 44. http://dx.doi.org/10.18203/2320-1770.ijrcog20205752.

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Background: Pregnancy is a serious pathology of the first trimester of pregnancy and is the leading cause of death. The objective of our work was to determine the hospital prevalence of ectopic pregnancy (EP), to describe the epidemiological, clinical and therapeutic profile given the often-haemorrhagic context at Laquintinie Hospital in Douala.Methods: We carried out a retrospective study over 10 years, from January 1st, 2007 to December 31st, 2016, using the operating theatre registers and the files of patients admitted during this period for ectopic pregnancy in the gynaecology and obstetrics department of the Laquintinie Hospital in Douala.Results: A total of 905 cases of EP for 32,595 deliveries were recorded, for an overall incidence of 2.8%. EP mainly affected the age group of 25 to 35 (60.6%), single people (57.9%) and housewives (46.6%). The risk factors found were similar to those of cervical cancer, namely multiple sexual partners (80.4%), the precocity of sexual intercourse under 18 years (54.1%) and sexually transmitted infections (52.5%). The symptomatic triad (pelvic pain, amenorrhea and metrorrhagia) was found in 46.1% of cases with a respective order of frequency of 96.9%, 77.3% and 63.6% The management was essentially surgical by radical laparotomy (97% of cases). Two of the 07 deaths were due to religious considerations.Conclusions: EP remains a frequent pathology in our environment with a heavy toll of tubal amputations and death.

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Molero Samuelson, Yasmina, Sheilagh Hodgins, Agne Larsson, Peter Larm et Anders Tengström. « Adolescent Antisocial Behavior as Predictor of Adverse Outcomes to Age 50 ». Criminal Justice and Behavior 37, n^o 2 (26 octobre 2009) : 158–74. http://dx.doi.org/10.1177/0093854809350902.

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The study examined associations between antisocial behavior (ASB) before age 15 and eight adverse outcomes from age 21 to 50 among 1,623 men and 324 women who as adolescents consulted a clinic for substance misuse problems. Outcomes were documented using Swedish national registers and included death, hospitalization for physical illnesses related to substance misuse, mental illness, self-inflicted harm, substance misuse, convictions for violent and nonviolent crimes, and poverty. ASB before age 15 was associated with increased odds of all outcomes in adulthood except hospitalization for mental illness after adjusting for low family socioeconomic status, sex, Sex × ASB, and substance misuse in adulthood and with an increased number of adverse outcomes up to age 50. No gender differences were detected.

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Garipova, Railya V., Leonid A. Strizhakov, Yuri Yu Gorblyansky et Sergey A. Babanov. « New coronavirus infection as an occupational disease : complex expert cases ». Russian Journal of Occupational Health and Industrial Ecology 61, n^o 11 (6 décembre 2021) : 720–25. http://dx.doi.org/10.31089/1026-9428-2021-61-11-720-725.

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Introduction. The professional activity of medical workers (MW) is in close contact with daily contact with various factors of the production environment: physical, chemical, biological, and labor processes. Until 2020, tuberculosis and viral hepatitis prevailed in the structure of occupational diseases (OD) of the medical workers in the Russian Federation. According to the State report "On the state of sanitary and epidemiological welfare of the population in the Russian Federation in 2020," the first ranking the second place in the structure of occupational diseases, depending on the impact of harmful production factor took the illnesses associated with the action of biological factors - 20,19%, while the main reason for the growth in the incidence of healthcare workers in coronavirus infection COVID-19 (further COVID-19). The study aims were to identify problematic aspects in the establishment of the COVID-19 work from MW. Materials and methods. We have given descriptions of clinical cases, as well as a retrospective analysis of issues of OD according to the patient registers of the following medical institutions: the Center of Occupational Pathology of Sechenov University, the Republican Center of Occupational Pathology of the Ministry of Health, Republic of Tatarstan, the Regional Center of Occupational Pathology of the Samara Region. Results. In 2020, COVID-19 was the most common OD with fatal outcomes and complications in healthcare workers. Today, difficulties in determining the connection of COVID-19 with the profession arise when assessing the epidemiological history, the consequences after a coronavirus infection, and the formulation of the diagnosis. Conclusions. For a qualitative examination of the connection of COVID-19 with the profession, it is necessary to develop a list of clinical conditions with the definition of the timing of complications.

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Vaidya, Karishma Malla, Gehanath Baral et Bigya Shrestha. « Two Years Trend of Cervical Screening and Precancerous and Cancerous Lesion in Cervical Biopsy in Paropakar Maternity and Women's Hospital ». Nepal Journal of Obstetrics and Gynaecology 13, n^o 3 (31 décembre 2018) : 48–50. http://dx.doi.org/10.3126/njog.v13i3.23430.

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Aims: To determine the detection rate of cervical lesion by cervical Pap test and to see the ongoing trend of Pap testing in the hospital. Methods: The retrospective study was conducted in department of pathology, Paropakar Maternity and Women's Hospital, Thapathali, Kathmandu, Nepal from 2016 to 2018. Pap testing sample received in the department were included in the study. All the data were retrieved from computers and registers at record section and histopathology unit. Results: There were 5.49% (1688 out of 30725) and 6.12% (1779 out of 29062) of gynecology out-patients had Pap test in first and second year respectively. Epithelial cells abnormalities were seen in 6.1% (104) and 4.83% (86) in first and second year respectively. Cervical biopsy sample in first year and second year had precancer and cancerous lesion in 29.55% (94 out of 318) and 22.01% (59 out of 268) in second year. Conclusions: Epithelial abnormalities seen in Pap test could detect quite a good proportion of abnormal cervical lesion in biopsy specimen of cervix.

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Bjerregaard, Beth, et Ole B. Larsen. « The Danish Pathology Register ». Scandinavian Journal of Public Health 39, n^o 7_suppl (juillet 2011) : 72–74. http://dx.doi.org/10.1177/1403494810393563.

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Kaleda, V., et V. Migalina. « Psychopathological and clinical-typological aspects of youth chronic endogenous depression ». European Psychiatry 65, S1 (juin 2022) : S370. http://dx.doi.org/10.1192/j.eurpsy.2022.940.

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Introduction Youth ontogenesis contributes significantly to depressive disorders, causing pronounced atypia, a high level of comorbid pathology. A long-term depressive state lead can to persistent, adverse consequences. Objectives To study the clinical, psychopathological and psychometric features of youth chronic endogenous depression (UCED). Methods 62 patients of the age 16-25 were examined clinically and psychopathologically; the patients were first hospitalized from 2017 to 2020 for a chronic depressive state with non-psychotic mental disorders (ICD-10: F31, F32, F33, F34, F21 keys) lasting more than two years. Psychometric assessment was done by HDRS, SOPS, and SANS. Results UCED are characterized by a pronounced atypia with a predominance of symptoms for negative affectivity with apathy, anhedonia, physical and mental asthenia, depressive devitalization. In contrast with non-chronic youth depressions, cognitive disorders, motor inhibition, a large proportion of comorbid pathology are presented in the chronic ones. Depending on the prevalence of additional psychopathological disorders, 2 types were distinguished: Type I – depression with a clear-cut affective psychopathological structure (54.8%, 34 patients); Type II - depression with the symptoms of other than affective registers (45.2%, 28 patients). Psychometric assessment on the HDRS scale, in the sub-scale “negative symptoms” of the SOPS scale, in the sub-scale “anhedonia-associality” of the SANS scale showed a greater severity of psychopathological symptoms in type II depression (p<0.05). Conclusions The obtained data confirm the differences between UCED and non-chronic youth depressions and demonstrate the aggravating effect of symptoms of the non-affective spectrum on the severity of UCED and the level of negative affectivity. Disclosure No significant relationships.

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El Omari, H., A. Chahlaoui, F. Talbi, K. Ouarrak et A. El Ouali Lalami. « Impact of Urbanization and Socioeconomic Factors on the Distribution of Cutaneous Leishmaniasis in the Center of Morocco ». Interdisciplinary Perspectives on Infectious Diseases 2020 (3 janvier 2020) : 1–7. http://dx.doi.org/10.1155/2020/2196418.

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Background. Parasitic diseases, in particular leishmaniasis, are still a public health problem in several countries and in Morocco. Methods. The data used are those of epidemiological surveillance collected in the registers of the prefectural epidemiology cell (PEC); however, the socioeconomic data were obtained from the High Commissioner for Planning. The Pearson correlation test was used to determine the correlation between the different variables. Results. In total, 70 cases were recorded by the prefectural epidemiology cell (PEC) during the period from 2009 to 2015. 46% of the cases come from rural areas while 54% of the cases come from urban areas. The Pearson test shows the existence of a significant relationship between the number of cases recorded and the type of environment (r = 0.49, p value = 0.02), and population rate (R = 0.849 and p≤0.001). However, in our case, the poverty rate does not influence CL’s distribution. Conclusion. Our results show that the CL affects the majority of the municipalities with predominance of the urban environment, so the distribution of cases of this pathology is not influenced by the poverty; however, the urbanization and the number of inhabitants have a positive impact on the distribution of this scourge.

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Kumar, Akshaya. « Changing Landscape of Moral Registers and Urban Pathology in ‘Bombay’ Cinema : Decline of Biological Family and Birth of the Individual through Awara (1951), Deewar (1951), (1975) and Satya (1998) ». CINEJ Cinema Journal 1 (6 octobre 2011) : 116–25. http://dx.doi.org/10.5195/cinej.2011.20.

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This article attempts to map out the changing image of biological family as the central axis of collective moral imagination in Bombay Cinema. Tracing the journey of the nation through three iconic films that were massively successful and helped the nation construct its self-projection, Awara (1951), Deewar (1975), and Satya (1998), mark the birth of an individual who disengages from the epic imagination of Ramayana and Mahabharata and arrives in the dark modern metropolis of post-liberalization India, not as a star figure but in a forever exile confronting, heroically indeed, a pathological condition of his exiled larger collective.

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Mohan, Bhavya P., Jaylakshmy Payippat Leelamma, Letha Vilasiniamma et Suresh Bhat. « Histopathological Spectrum of Nephrectomies - A 10 Year Descriptive Study from a Tertiary Care Center in South India ». Journal of Evidence Based Medicine and Healthcare 7, n^o 47 (23 novembre 2020) : 2752–56. http://dx.doi.org/10.18410/jebmh/2020/565.

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BACKGROUND Nephrectomy is the standard surgical treatment of neoplastic and non-neoplastic lesions in the kidney and provides more insight into the detailed histopathology of renal lesions. We wanted to identify the age groups, gender distribution and different histopathological types and subtypes of non-neoplastic and neoplastic lesions in nephrectomy specimens over a period of ten years. METHODS A retrospective analysis was done over a period of ten years (January 2006 to December 2015). All nephrectomy specimens received in the Department of Pathology, Government Medical College, Kottayam were recorded from histopathology registers and analysed with regard to age, gender and histopathological types. RESULTS A total of 532 lesions was encountered in our analysis. Males (61.8 %) were affected more than females (38.2 %). Lesions were more on the left side (50.8 %) than right side (49.2 %). Non-neoplastic lesions (53 %) outnumbered neoplastic lesions (47 %). Inflammatory and obstructive causes constituted the majority (43.8 %) in non-neoplastic lesions and renal cell carcinoma was the commonest neoplasm (71.2 %). CONCLUSIONS There is a wide age distribution of renal diseases in the present study. Inflammatory and obstructive conditions constituted the most common indication for nephrectomy, followed by malignant tumours. KEYWORDS Renal Cell Carcinoma, Nephrectomy, Pyelonephritis, Simple Renal Cyst, Wilms Tumour

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Stefanovski, Petko Hristov, Radev Vladimir Radkov, Tsankov Lyubomir Ilkov, Tonchev Pencho Tonchev, Todorova Yoana Mladenova, Kovachev Vihar Manchev et Radev Radko Nikolov. « Analysis of mortality in the emergency department at a university hospital in Pleven ». Journal of International Medical Research 45, n^o 5 (27 juillet 2017) : 1553–61. http://dx.doi.org/10.1177/0300060517707901.

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Objective To identify the demographic patterns of mortality, the time spent before death in the emergency department (ED), and the causes of fatal outcomes. Methods We performed a 5-year (01/01/2011 to 01/01/2016) retrospective analysis of all non-traumatic deaths in the ED of the UMHAT – Pleven. To extract the necessary information, we used the registers in the ED until the patients’ death. Results Among 156,848 patients in the study period, 381 died and the mortality rate was 2.4/100000. The male:female ratio was 1.48:1. The 71–80 years age group was the most affected. The mean (SD) age of patients who died in the ED was 69.9 ± 8.4 years. Most non-traumatic deaths (222 cases) were due to cardiovascular disease. Most patients (70.9%) died within 2.3 h after arrival. The factors contributing to mortality included poverty, transporting the patient to hospital too late, and a lack of developed care centres for terminally ill patients. Conclusion Most patients die within approximately 2 h after arrival at the ED. The main cause of death is acute myocardial infarction. Pulmonary embolism remains unrecognized in most patients (69%). Oncological pathology is among the main causes (7.4%) of mortality.

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Мерабишвили, В. М., Д. М. Дубовиченко, М. Ю. Вальков, А. М. Щербаков et Э. Н. Мерабишвили. « AGE-RELATED FEATURES OF THE DYNAMICS OF MORBIDITY AND MORTALITY, LOCALIZATION AND HISTOLOGICAL STRUCTURES OF RECTAL CANCER (POPULATION STUDY) ». Успехи геронтологии, n^o 5 (22 janvier 2021) : 900–907. http://dx.doi.org/10.34922/ae.2020.33.5.010.

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Рак прямой кишки (РПК) - это злокачественная опухоль дистального отдела толстой кишки эпителиального происхождения. Ежегодно в России регистрируется более 30 тыс. (30 969 в 2018 г.) новых случаев РПК и 16 тыс. (16 151) случаев смерти. Индекс достоверности учета (отношение числа умерших к заболевшим) составляет 0,52 %. РПК относится к локализациям со средним уровнем летальности. В Северо-Западном Федеральном округе зарегистрировано более 3 тыс. первичных случаев РПК (3 285 в 2018 г.). Государственная статистика РПК представляет данные о заболеваемости и смертности населения по трем рубрикам МКБ-10 вместе (С19-21). Детальная разработка данных не только отдельно по каждой рубрике МКБ-10, но и по четвертому знаку возможна только по материалам баз данных раковых регистров. Созданный нами Популяционный раковый регистр Северо-Западного Федерального округа насчитывал на 01.01.2019 г. более 1 млн (1 067 661) случаев злокачественных новообразований (ЗНО), в том числе РПК - 50 745 случаев, или 4,8 %. Удельный вес РПК близок к среднероссийскому - 4,9 %. В работе представлена детальная структура онкологической патологии по РПК. Ведущая роль из трех указанных рубрик принадлежит ЗНО прямой кишки (С20) - 75,4 %; 19,8 % приходится на ЗНО ректосигмоидного отдела (С19) и только 4,7 % на С21 - ЗНО ануса и анального канала. По всем этим рубрикам представлена динамика структуры, которая оказалась достаточно устойчивой. Rectal cancer is a malignant tumor of the distal colon of epithelial origin. Every year, more than 30,000 (30 969 - 2018) new cases of Rectal cancer and 16,000 deaths (16 151) are registered in Russia. The index of reliability of accounting (the ratio of the number of dead to sick) is 0,52 %. Rectal cancer refers to localities with an average mortality rate. In the North-Western Federal district, more than 3 thousand primary cases of Rectal cancer were registered (3285 - 2018). The state statistics of the Rectal cancer provides data on morbidity and mortality in three categories of ICD-10 together (C19-21). Detailed development of data not only separately for each category of ICD-10, but also for the fourth sign is possible only from the data bases of cancer registers. As of 01.01.2019, the Population cancer register of the North-Western Federal district created by us totaled more than 1 million cases of malignant tumors (1 067 661), including Rectal cancer - 50 745 cases, or 4,8 %. The share of the Rectal cancer is close to the national average - 4,9 %. The article presents a detailed structure of cancer pathology in Rectal cancer. The leading role of the 3 speciﬁed categories belongs to the rectal malignant tumors (C20) - 75,4 %, 19,8 % falls on the malignant tumors of the rectosigmoid department (C19) and only 4,7 % on the C21 - malignant tumors of the anus and anal canal. For all these categories, the dynamics of the structure is presented, which proved to be quite stable.

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Smirnova, M. S., A. V. Smirnov, O. A. Smirnova et K. A. Medvedev. « Analysis of fatal cases according to COVID-hospital data ». Clinical Medicine (Russian Journal) 100, n^o 4-5 (21 juillet 2022) : 214–20. http://dx.doi.org/10.30629/0023-2149-2022-100-4-5-214-220.

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New coronavirus infection (COVID-19) hospital mortality rate is high but vary in different countries. The aim of the study: to analyze the mortality in the COVID-hospital for the period from January to December 2021 taking into account the age as well as the causes of deaths and comorbidity of patients who died in January–February 2021. Material and methods. Hospital mortality was evaluated according to the registers in 2021. The case histories of patients who died in January–February 2021 were analyzed retrospectively. Results. 984 pa of patients over 60 years old (14.38%) was higher compared to younger people (3.98%), and increased with age. The most frequent complications in 84 patients who died in January–February were acute respiratory distress syndrome, infectious-toxic shock, acute cerebrovascular accident. 78 (92.85%) of the deceased had 2 or more concomitant diseases. Cardiac pathology, chronic kidney disease and diseases of the endocrine system were the leaders in frequency. Vaccination for the previous 6 months was carried out in 3 (3.57%) patients. Conclusion. Mortality rate in the COVID-hospital in 2021 was 10.49% and was significantly higher among patients over 60 years old. A further increase in age was associated with an increase in mortality. The majority of the patients, 78 out of 84 (92.85%) who died in January–February, had multimorbidity.

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Anjaneyulu, K., A. Geetha, B. Vidya Sagar, K. Revathy et Kasu Bala Prathyusha. « VISUAL HANDICAP CERTIFICATES : A TOOL TO EVALUATE THE CAUSES FOR PERMANENT VISUAL IMPAIRMENT IN KURNOOL DISTRICT ». International Journal of Advanced Research 11, n^o 01 (31 janvier 2023) : 57–60. http://dx.doi.org/10.21474/ijar01/16219.

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Aim: To analyze the causes of visual impairment amongst the patients coming for the visual handicap certificate and its application in eye health planning to prevent the blindness. Methods and Materials: A retrospective data analysis of medical records of 1020 people who had applied for the visual handicap certification. Examination was done by the ophthalmologists appointed for the handicap board. BCVA < 20/60 to 20/120 in better eye was included in visual impairment Cat I (40%) and BCVA 20/200 or less is blindness category II to IV (75%to100%). Results: Majority of them belonged to age group of 16 year to 45 years of age, 264 cases got rejected, 530 individuals had mild visual Impairment (< 40%), in 136 individualÂ’s moderate visual impairment (40%) was found in 90 individuals had sever visual impairment to blindness. Overall Optic Atrophy was the most common cause followed by Retinitis Pigmentosa, followed by macular pathology followed by corneal opacity followed by phthisis bulbi followed by amblyopia. Conclusion: Visual handicap registers are useful for the rehabilitation of visually impaired individuals and to assess the pattern or causes of blindness in particular area. The most common etiological factors causing visual impairment in our study are preventable so we propose the empowerment of the school health system and general health delivery system.

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MASHINGAIDZE, Terence. « ZIMBABWE : GUKURAHUNDI VICTIMS’ MONOLOGUES, STATE SILENCES AND PERPETRATOR DENIALS, 1987-2017 ». Conflict Studies Quarterly, n^o 32 (5 juillet 2020) : 3–20. http://dx.doi.org/10.24193/csq.32.1.

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The Zimbabwean government instigated Gukurahundi massacres resulted in the death of around 20 000 people. The majority of the victims belonged to the Ndebele ethnic group while the Fifth Brigade, a Shona dominated military outϐit, were the main perpetrators of the mass killings. The atrocities ended with the signing of the Unity Accord of December 1987 between the ruling ZANU (PF) party, which had masterminded the atrocities, and the opposition (PF) ZAPU, whose supporters had borne the brunt of state highhandedness. After the cessation of hostilities the Zimbabwean government frustrated open conversations and public commemorations of the massacres. What conversations on Gukurahundi that took place were largely victims’ monologues. To interrogate this state instigated silencing of exposure and remembrance the article suggests an exigency for counter-narrating erasures of memories of harm and impunity. In the aftermath of massacres, I argue, harmed communities embolden themselves and coalesce their fractured senses of self by openly memorialising their collective suffering through open conversations about their shared victimhood, commemorations, and the assembling of monuments. The Robert Mugabe led government’s foreclosure of such avenues for public acknowledgements of mass injuries that are supposed to serve as visceral registers of what societies should remember to avoid in the future reveals its disregard for the wounded humanity of the constitutive political other. Thus, Gukurahundi as an historical episode reveals the pathology of mass harm silenced and rendered insigniϐicant by the state.

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Hounkpatin, Spéro H. Raoul, Fatiou Alabi Bouraima, Marius Claude Flatin, Marie-Claire Balle et Luc Valere C. Brun. « Epidemiological profile of oral cancers in Benin ». International Journal of Otorhinolaryngology and Head and Neck Surgery 6, n^o 2 (24 janvier 2020) : 234. http://dx.doi.org/10.18203/issn.2454-5929.ijohns20200134.

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Background: The objective of the study was to study the epidemiological profile of malignant tumours of the oral cavity in Benin from January 2009 to 31 December 2014.Methods: This was a descriptive cross-sectional study that examined cancers of the oral cavity collected in the registers of the 5 anatomy and pathology laboratories in Benin as well as the only hospital in the country that sends its requests for histological examinations abroad. Results: With a rate of 19.8%, oral cavity cancer was the most frequent cancer localization in the ENT, head and neck sphere in Benin. The most frequent sites of cancers in the oral cavity were the palate (32.2%) followed by the tongue (25.4%) and the inner face of the cheeks (16.9%). The average age of the patients was 53.18±20.60 years with extremes of 1 year and 90 years. The sex ratio was 0.90. Squamous cell carcinoma was the most common histological type with 67.80%.Conclusions: Cancer of the oral cavity must be a priority for health authorities in Benin. Research must be initiated to determine the factors that contribute to it.

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Gunko, N., K. Loganovsky, V. Buzunov et N. Korotkova. « AGING OF THE CHORNOBYL CATASTROPHE SURVIVORS AND PROBLEMS OF THEIR MENTAL HEALTH SURVEY ». Проблеми радіаційної медицини та радіобіології = Problems of Radiation Medicine and Radiobiology 26 (2021) : 162–87. http://dx.doi.org/10.33145/2304-8336-2021-26-162-187.

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Background. Depopulation processes in Ukraine have been affected by the Chornobyl catastrophe (ChC), but the rate of demographic aging of survivors remains uncertain. Although the mental health disorders of the survivors are recognized internationally, problems of their research remain unresolved. Thus, these areas of research are relevant. Objective is to determine the rate of demographic aging of survivors of the Chornobyl NPP (ChNPP) accident and to analyze the state of their mental health survey, outlining solutions. Materials and methods. Information and statistical sources for 1986–2019 of the Ministry of Health of Ukraine and the State Statistics Service of Ukraine on the age of the ChC survivors are used. The results of previous own research and other scientists using the data of the Clinical and Epidemiological Register (CER) of the State Institution «National Research Center for Radiation Medicine of the National Academy of Medical Sciences of Ukraine» (NRCRM), the State Register of ChC survivors (SRU), and the Department of Radiation Psychoneurology, Institute of Clinical Radiology, NRCRM are integrated. Theoretical, general scientific, demographic and mathematical-statistical research methods and documentary analysis are used. Results. It is shown that in 2018, compared to 1995, the number of the ChC survivors, who are under the supervision of the Ministry of Health of Ukraine, decreased by almost 987 thousand. The part of people born from persons of the 1st–3rd accounting groups increased in the structure of survivors (from 13.1 % in 1995 to 13.6 %), and this decreased in persons living or lived in the territories subject to supervision (75.1 % and 63.1 %, respectively), but in evacuees and Chornobyl clean-up workers (liquidators) this did not change significantly. A high level of aging of the ChC survivors (except for the 4th group) is revealed: liquidators – 59.0 %; evacuees – 25.0 %, and residents of radioactively contaminated territories (RCT) – 30.7 %. It has been proved that the countries of RCT differ significantly in the number of the ChC survivors and their structure. The increase in the post-accident period indicators of the level of aging and the average age of the RCT population indicates negative changes in age parameters and the need to continue research to identify factors «responsible» for such changes. Long-term mental health disorders and neuropsychiatric effects in the ChC survivors have been identified – an excess of cerebrovascular pathology and neurocognitive deficits, especially in liquidators, which may indicate an accelerated aging. Radiation risks have been revealed for acute and chronic cerebrovascular pathology and organic mental disorders of non-psychotic and psychotic levels. Neurophysiological and molecular-biological atypia of aging processes under an exposure to low doses of and low dose rate of ionizing radiation have been found. The psyche under the age of 40 years old at the time of exposure is more vulnerable. Existing statistical and registry data underestimate the level of mental disorders in the population of Ukraine, including the ChC survivors by an order of magnitude. Conclusions. The ChC survivors are aging in the country. The negative tendencies in age parameters of survival indicate the need to continue research to identify the factors «responsible» for such changes. Mental health disorders and neuropsychiatric effects in the ChC survivors are underestimated. It is necessary to create a national psychiatric registry of Ukraine and long-term (lifelong) monitoring of survivors with well-planned clinical and epidemiological studies of general and mental health with reliable dosimetric support based on national registries using the latest information technologies. Key words: Chornobyl catastrophe survivors, demographic aging, mental health, registers.

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Ludvigsson, Jonas F., Olle Kämpe, Benjamin Lebwohl, Peter H. R. Green, Shonni J. Silverberg et Anders Ekbom. « Primary Hyperparathyroidism and Celiac Disease : A Population-Based Cohort Study ». Journal of Clinical Endocrinology & ; Metabolism 97, n^o 3 (1 mars 2012) : 897–904. http://dx.doi.org/10.1210/jc.2011-2639.

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Context: Celiac disease (CD) has been linked to several endocrine disorders, including type 1 diabetes and thyroid disorders, but little is known regarding its association to primary hyperparathyroidism (PHPT). Objective: The aim of the study was to examine the risk of PHPT in patients with CD. Design and Setting: We conducted a two-group exposure-matched nonconcurrent cohort study in Sweden. A Cox regression model estimated hazard ratios (HR) for PHPT. Participants: We identified 17,121 adult patients with CD who were diagnosed through biopsy reports (Marsh 3, villous atrophy) from all 28 pathology departments in Sweden. Biopsies were performed in 1969–2008, and biopsy report data were collected in 2006–2008. Statistics Sweden then identified 85,166 reference individuals matched with the CD patients for age, sex, calendar period, and county. Main Outcome Measure: PHPT was measured according to the Swedish national registers on inpatient care, outpatient care, day surgery, and cancer. Results: During follow-up, 68 patients with CD and 172 reference individuals developed PHPT (HR = 1.91; 95% confidence interval = 1.44–2.52). The absolute risk of PHPT was 42/100,000 person-years with an excess risk of 20/100,000 person-years. The risk increase for PHPT only occurred in the first 5 yr of follow-up; after that, HR were close to 1 (HR = 1.07; 95% confidence interval = 0.70–1.66). Conclusions: CD patients are at increased risk of PHPT, but the absolute risk is small, and the excess risk disappeared after more than 5 yr of follow-up.

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Kleif, Jakob, Lau C. Thygesen et Ismail Gögenur. « Validity of the diagnosis of appendicitis in the Danish National Patient Register ». Scandinavian Journal of Public Health 48, n^o 1 (19 mars 2018) : 38–42. http://dx.doi.org/10.1177/1403494818761765.

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Aims: Appendicitis is a common disease. The nationwide Danish National Patient Register provides an important data source for epidemiological research. Data used in register-based epidemiological research needs to be validated. We aimed to validate the diagnosis of appendicitis in the Danish National Patient Register. Methods: From 1997 to 2015 nationwide data from the Danish National Patient Register, the Danish Pathology Register, and the Danish Civil Registration System were used to validate the diagnosis of appendicitis or the combination of the diagnosis for appendicitis and surgical removal of the appendix in the Danish National Patient Register. Sensitivity, specificity, and positive and negative predictive values were calculated using pathology reports as golden standard. Results: Diagnosis of appendicitis in the Danish National Patient Register had a sensitivity, specificity, positive predictive value, and negative predictive value of 0.928 (95% confidence interval (CI): 0.927; 0.930), 0.995 (95% CI: 0.995; 0.995), 0.769 (95% CI: 0.767; 0.771), and 0.999 (95% CI: 0.999; 0.999). A diagnosis of appendicitis and a procedure code for surgical removal of the appendix had a sensitivity, specificity, positive predictive value, and negative predictive value of 0.886 (95% CI: 0.885; 0.888), 0.998 (95% CI: 0.998; 0.998), 0.895 (95% CI: 0.894; 0.897), and 0.998 (95% CI: 0.998; 0.998). Conclusions: The diagnosis of appendicitis alone or in combination with the registered surgical removal of the appendix in the Danish National Patient Register showed acceptable validity. Whether to use the diagnosis for appendicitis only or in combination with procedure codes for the removal of the appendix depends on whether high sensitivity or high positive predictive values are warranted.

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García Hernández, I., L. Fernández de la Fuente Bursón, P. Muñoz Reinoso, D. V. Mendoza Mendoza, B. Hernández-Cruz, P. González Moreno et J. J. Pérez Venegas. « AB1159 HIGH PREVALENCE MUSCULOSKELETAL PATHOLOGY : A CHALLENGE FOR PRIMARY ATTENDING PHYSICIANS. WHAT DO WE RHEUMATOLOGISTS CONTRIBUTE TO ? » Annals of the Rheumatic Diseases 79, Suppl 1 (juin 2020) : 1870.1–1870. http://dx.doi.org/10.1136/annrheumdis-2020-eular.4593.

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Background:Musculoskeletal Diseases (MSKD) represent one of the main health problems burdens worldwide. They cause a significant functional, quality of life and socioeconomic impact. Knee and lumbar osteoarthritis are the most prevalent1. MSKD can be assessed by different kind of specialists: Orthopedic and Traumatology Surgery (OTS), Rheumatology and Rehabilitation, each of them focused at one of the distinct aspects of the same disease. It is the General Practitioner (GP) consultations that usually act as a gateway to specialized care. However, this derivation is carried out in non-standardized manners that leads to an evaluation from a sometimes wrong selected specialist or sometimes overlap management between several of them2. The result is an endless waiting list in an overburden health system that cannot solve people’s health issues. In 2018, only in our area, 32.894 patients with MSKD were referred from GP to the different medical consultations: OTS (65%), Rehabilitation (25%) and Rheumatology (10%). Furthermore, there are specialized consultations called“Primary Trauma”to which GP can refer which are managed indistinctly by any of the 3 specialists mentioned before.Objectives:The following study aims to assess by collecting data in one of these consultations, how these pathologies are referred to the different specialist and the role that the rheumatologist plays in its management.Methods:From January to March 2019, 300 consecutive patients´ medical records from the HUVM area that were sent to “Primary Trauma” consultations and attended by a rheumatologist have been reviewed. The reason for consultation, tests and referrals requested, diagnoses reached and procedures and other therapeutic actions performed were collected. Descriptive statistics with percentages and mean are showed.Results:The average age of the patients was 51 years [7-88], 57% (170) women and 43% (130) men. The most frequent reasons for referral were knee pain (26), foot pathology (23%), low back pain (12%) and carpal tunnel syndrome (6%). 68% (204 patients) attended the consultation with some test already performed request in primary care, mostly radiographs (61%) and MRI scan (34%). After the first assessment during consultation, only 31% required new studies. The diagnoses that were most frequently established are showed in table 1: degenerative knee pathology (29%) was the most prevalent. 60% of the patients assessed were given exercise tables and/or postural recommendations. 14% received an infiltration on the same day of the visit. Only 78 patients (26%) needed to be reviewed later in those consultations. Of the remaining 222 (74%), 81 (27%) were referred to other specialists. 56 of them (19%) went to OTS to a surgical evaluation, most frequently of the knee (32%), hand (27%) and foot (23%). 141 (47%) were discharged and referred to GP´s for follow ups.Table 1.Diagnoses.N%Degenerative knee pathology6729Plantar support alterations3415Lumbar osteoarthritis198Deformities of the feet177Mechanical metatarsalgia125Plantar fasciitis94Carpal tunnel syndrome94Conclusion:The prevalence of MSKD found in medical consultation coincides with the national registers. Most patients did not need to be referred to surgical units. The role of the Rheumatologist is to take a comprehensive care for the patient, focusing on giving an effective evaluation and quick solution to his MSKD. In short, if the most prevalent MSKD are not subsidiary of surgical treatment (at least initially), the specialist whom patients with MSKD should be referred would be the rheumatologist.References:[1]EPISER2016: Estudio de la prevalencia de las enfermedades reumáticas en población adulta en España. Sociedad Española de Reumatología. Madrid, 2018.[2]Conill EM et al. Waiting lists in public systems: from expanding supply to timely access? Reflections on Spain’s National Health System. Cien Saude Colet. 2011;16:2783–94.Disclosure of Interests:Isabel García Hernández: None declared, Lola Fernández de la Fuente Bursón: None declared, Paloma Muñoz Reinoso: None declared, Dolores V. Mendoza Mendoza: None declared, Blanca Hernández-Cruz Speakers bureau: Abbvie, Lilly, Sanofi, BMS, STADA, Paz González Moreno: None declared, José Javier Pérez Venegas: None declared

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Mikhaylova, N. M., et O. N. Sokolova. « Dementia in old age : from diagnosis to fatal outcome ». V.M. BEKHTEREV REVIEW OF PSYCHIATRY AND MEDICAL PSYCHOLOGY, n^o 3 (11 octobre 2020) : 64–72. http://dx.doi.org/10.31363/2313-7053-2020-3-64-72.

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Background: It is well known, that old age dementias steadily grow progressively worse and inevitably lead to fatal outcome. Mortality indices in foreign research largely vary, they are practically absent in domestic scientific studies, and official statistical data on the prevalence of dementia and the cause of death do not reflect the real situation. The Objective of the study was to perform the analysis of completed cases of late age dementias from the materials of observations in Alzheimer’s disease center of the Mental Health Research Center.Patients and Methods: Observational study, using prospective method of out-patient observation of subjects with dementias, who consulted Alzheimer’s disease center in 2007-2016 for the first time, made it possible to obtain reliable data on 217 patients, who died during this period.Results: More than one third of such cases (39%) referred to nosologically various dementias with an early onset of the disease. In more than half of the cases (58%) the cause of death was medical pathology. In the rest of the patients severe or terminal stage of the basic disease was noticed toward the end of life under conditions of home care.Conclusions: Holistic view of the clinical picture of old age dementias (from the onset of the disease till the fatal outcome) is necessary for creation of incidence registers and obtaining of science-based statistical indices of survival, mortality and causes of death. It is necessary to develop measures of assistance to families of patients with the most severe stage of dementias, creation of out-patient and in-patient network of hospices for this contingent of patients.

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Benz, Laura D., Peter K. Bode, Simone Brandt, Beate Grass, Cornelia Hagmann, Rabia Liamlahi, Bernhard Frey, Ulrike Held et Barbara Brotschi. « Placental findings are not associated with neurodevelopmental outcome in neonates with hypoxic-ischemic encephalopathy – an 11-year single-center experience ». Journal of Perinatal Medicine 50, n^o 3 (21 octobre 2021) : 343–50. http://dx.doi.org/10.1515/jpm-2020-0583.

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Abstract Objectives Although neonates with moderate to severe hypoxic ischemic encephalopathy (HIE) receive therapeutic hypothermia (TH), 40–50% die or have significant neurological disability. The aim of this study is to analyse the association of placental pathology and neurodevelopmental outcome in cooled neonates with HIE at 18–24 months of age. Methods Retrospective analysis of prospectively collected data on 120 neonates registered in the Swiss National Asphyxia and Cooling Register born between 2007 and 2017. This descriptive study examines the frequency and range of pathologic findings in placentas of neonates with HIE. Placenta pathology was available of 69/120 neonates, whose results are summarized as placental findings. As neonates with HIE staged Sarnat score 1 (21/69) did not routinely undergo follow-up assessments and of six neonates staged Sarnat Score 2/3 no follow-up assessments were available, 42/48 (88%) neonates remain to assess the association between placental findings and outcome. Results Of the 42/48 (88%) neonates with available follow up 29% (12/42) neonates died. Major placenta abnormalities occurred in 48% (20/42). Major placenta abnormality was neither associated with outcome at 18–24 months of age (OR 1.75 [95% CI 0.50–6.36, p=0.381]), nor with death by 2 years of age (OR 1.96 [95% CI 0.53–7.78, p=0.320]). Conclusions In this study cohort there could not be shown an association between the placenta findings and the neurodevelopmental outcome at 18–24 months of age.

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ANDONE, Ioana, Aurelian ANGHELESCU, Cristina DAIA et Gelu ONOSE. « Current synthetic overview on spinal cord injury epidemiological data ». Romanian Journal of Medical Practice 10, n^o 2 (30 juin 2015) : 117–23. http://dx.doi.org/10.37897/rjmp.2015.2.6.

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Aim. To have updated information on the epidemiology of spinal cord injury (SCI) is required for developing an adequate and effective related health policy strategies and consequent contextual decisions making regarding this category of patients and also for planning and implementing SCI prevention education and measures. Accordingly, the rationale of this article is to provide a systematic overview of the literature regarding SCI epidemiology. Material and methods. We reviewed epidemiological published reports and searched on internet specifically databases, from different centres, worldwide, about SCI, collecting descriptive data for properly estimating the incidence, prevalence, and/ or causes of SCI. Results. The global annual incidence rate is considered to be 23 cases of Traumatic Spinal Cord Injury (TSCI) per million (179,312 new cases per annum – results provided by World Health Organisation’s (WHO) in 2007). Prevalence per million inhabitants varies quite largely among statistics in different countries (from 280 in Finland to 681 in Australia, 755 in the United States of America or maybe even more, and even bigger in Canada). Men more commonly suffer from this kind of pathology and the direction of SCI evolution is to have a higher cord lesion level (more tetraplegics than paraplegics) and age at injury. Conclusion. Even if the results of this literature review showed that the SCI incidence and prevalence are rising, they did not suffer significant changes in the last three decades of time. The prevalence surveys remain poor, mainly because a basic requirement for having correct and appropriately updated figures would need national and or regional electronic dedicated registers of evidence, and this is not a situation frequent enough. But the incidence studies from USA and Europe have been increased in the last years. This article asserts the need for improving the SCI data standardised collection in many countries, especially in the ones from low developed or emergent areas.

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Golovchenko, Tverdokhlebova, Shirinyan, Kiosova et Ermakova. « PRACTICAL ASPECTS OF LABORATORY DIAGNOSIS OF ENTEROBIASIS ». THEORY AND PRACTICE OF PARASITIC DISEASE CONTROL, n^o 20 (14 mai 2019) : 189–93. http://dx.doi.org/10.31016/978-5-9902340-8-6.2019.20.189-193.

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In the structure of the incidence of parasitic invasions in the Russian Federation, enterobiosis – contact parasitosis is the dominant helminthiasis. According to the state report, the predominantly childish population of the country suffers from enterobiasis. So, the share of children under 17 years old in the structure of patients with enterobiasis in 2017 was 97.5% [1]. In recent years, there has been no steady positive incidence of this helminthiasis, so in 2014 the incidence of enterobiosis in the population was 148.72 per 100 thousand of the population, and in 2017 this figure increased to 154.7 per 100 thousand of the population. According to the analysis of the medical records of patients of the clinic of infectious and parasitic diseases, the percentage of adults among patients with enterobiasis in the last 5 years amounted to 20.9%. This fact is explained by the decrease in the number of surveys and the selection of ineffective methods for diagnosing this parasitosis among the adult population of the Russian Federation.One of the most important non-specific laboratory signs of parasitic invasion is the leukemoid reaction of the eosinophilic type. Among patients referred to the clinic for the purpose of eliminating parasitic diseases, the proportion of patients with eosinophilia was 35.8%. The diagnosis of parasitic invasion was made in 25.0% of patients, the rest suffered from various allergic diseases, neoplasms, pathology of the gastrointestinal tract, etc. The structure of parasitic diseases was represented mainly by 13 nosological forms. Enterobiasis was most frequently recorded (43.8%), the proportion of larvaceous helminth infections (echinococcosis, ostocarosis, dirofilariasis) was 19.5%, other gastrointestinal worms (teniarinhoz, diphyllobotriosis, opisthorchiasis, strongyloidosis) – 22.8%. 6.3% of patients had a combined invasion of two or more parasites. The clinic annually registers up to 7.6% of cases of rare imported parasitosis (loaosis, leishmaniasis, cutaneous larva migrans, etc.).

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Rossi, Federica, Sara Auricchio, Agnese Binaggia, Vincenzo L’imperio, Fabio Pagni et Federico Pieruzzi. « Tumour incidence in Fabry disease : A cross-sectional study ». Journal of Onco-Nephrology 3, n^o 2 (juin 2019) : 80–87. http://dx.doi.org/10.1177/2399369319852117.

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Background: Recently, a possible correlation between altered glycosphingolipid metabolism, that occurs in Fabry disease, and cancer development has been suggested. We analysed both incidence and prevalence of benign and malignant tumours in a Fabry patient cohort and compared them with the Italian general population. The analysis of major risk factors was performed. Methods: A total of 53 Fabry patients, followed by Nephrology Unit of San Gerardo Hospital (Monza, Italy), were retrospectively enrolled. Primary outcome was cancer development during the follow-up period (2007–2017). Cancer prevalence and incidence rate were calculated and compared to those in the Italian general population, acquired from public report on cancer estimates produced by the Cancer Registers’ Italian Association. Fisher’s exact test and multivariate analysis were performed to identify significant risk factors. Results: Nine (17%) patients were diagnosed with malignant neoplasia (stage T1–T3, N0M0). Most of them were female (77.8%) and were 59 ± 9 years old. In the benign tumour group, different lesions, ranging from adenoma to dysplasia, were recorded. Italian cancer prevalence is currently 5.5%, while in our population it was 17%; the incidence rate ratio of the Fabry population compared with the general population was 2.66 (95% confidence interval from 1.33 to 5.32). The risk factor analysis has revealed that older age was a negative factor for cancer onset, while enzyme replacement therapy had a protective role effect against cancer in Fabry patients. Conclusion: Cancer could be an important associated pathology in Fabry patients. Their altered glycosphingolipid metabolism may have an oncogenic role. Further studies are needed to clarify the relationships between Fabry disease and cancer onset. Tumours in Fabry subjects could be diagnosed at an early stage allowing patients to have a concrete chance of treatment success.

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Risser, Daniele, Anneliese Bönsch et Barbara Schneider. « Does drug abuse lead to future criminal behaviour ? An analysis based on criminal registers of 117 drug-related deaths, examined in 1992 at the Institute of Forensic Medicine in Vienna ». Journal of Clinical Forensic Medicine 2 (mars 1995) : 27. http://dx.doi.org/10.1016/1353-1131(95)90182-5.

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Boiko, I. V., et O. N. Andreenko. « Critical analysis of attempts to recognize an occupational disease as a non-insured event on the basis of the peculiarities of the disease investigation procedure ». Russian Journal of Occupational Health and Industrial Ecology, n^o 12 (25 décembre 2019) : 1020–24. http://dx.doi.org/10.31089/1026-9428-2019-59-12-1020-1024.

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The current legislation clearly declares the guarantee of insurance compensation to the employee in connection with the diagnosis of occupational disease. Meanwhile, in recent years there have been precedents of recognition by the Social Insurance Fund of established cases of occupational diseases not insured in connection with claims to the correctness of the procedure of their investigation.The article analyzes court cases in which patients with an established diagnosis of occupational disease challenged the refusal of the insurer (Social Insurance Fund) in the appointment of insurance payments, motivated by a reference to violations of the established procedure for the investigation of occupational diseases.The insurer motivated its refusal to assign insurance payments to patients with the following arguments:— appeals of the patient to doctors at the time of establishment of the preliminary diagnosis of occupational disease were not entered in registers of rendering medical services;— sanitary and hygienic characteristics of working conditions of the patient was not based on proper documents;— examination of the connection of the disease with the profession was carried out on the personal application of the patient without registration of the direction from the medical organization;— examination of the connection of the disease with the profession was carried out in the Department of professional pathology of a medical organization that is not a vocational center;— the staff of the Department of professional pathology did not meet the requirements of normative documents;— violation of rules of registration of the notice on establishment of the fi nal diagnosis of chronic occupational disease is allowed;— the representative of the Social Insurance Fund was not included in the commission that drew up the act on the case of occupational disease.In the vast majority of cases, the violations, if any, were of the nature of technical errors and did not affect the essence of the expert opinion on the existence of a connection between the disease and the profession. In such a situation, the categorical refusal to appoint insurance payments to the patient seems unreasonable. Th e claims of the Social Insurance Fund, with a constructive approach, could be settled without a court by contacting the insurer to medical organizations and health authorities. It is necessary to correct the regulations on compulsory insurance against accidents at work and occupational diseases. Th e rules of law should not allow categorical refusal in the appointment of insurance payments to the patient, whose diagnosis of occupational disease, which led to a decrease in working capacity, is established on the merits correctly. Claims of the insurer to the procedure of investigation of a case of occupational disease are most rationally considered in the pre-trial procedure within the framework of the dialogue of the Social Insurance Fund with local health authorities.

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Korkhmazov, V. T. « COVID-19 impact on hospitalization outcomes of patients with circulatory system diseases ». Innovative Medicine of Kuban, n^o 3 (21 septembre 2022) : 43–51. http://dx.doi.org/10.35401/2541-9897-2022-25-3-43-51.

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Background: The study is devoted to the impact of a new coronavirus infection in combination with other diseases on the hospitalization outcomes. Features of mortality in the population during COVID-19 pandemic, including from blood circulatory system diseases, have been studied. However, there are few studies based on the large amount of data on the cases and outcomes of providing specialized hightech medical care to patients with cardiovascular diseases (CVD) and concomitant diagnosis of COVID-19.Objective: The analysis of impact of a new coronavirus infection on the outcomes of hospitalization for circulatory system diseases.Material and methods: Information about more than 350 thousand cases of hospitalization of patients with blood circulatory system diseases in the context of the COVID-19 pandemic has been analyzed, of which in 1875 cases a concomitant diagnosis of COVID-19 was established. The sources of information are the depersonalized registers of compulsory health insurance accounts. For assessment of the obtained data methods of descriptive statistics, simple (unweighted) arithmetic mean values, mean values, specific weights of indicator values, a mean square (standard) deviation from mean values were used. The analysis and descriptive part of the work were carried out by means of the Microsoft Excel spreadsheet software package.Results: The outcomes of hospitalization of patients with suspected or confirmed diagnosis of COVID-19 were significantly worse than in other patients. Moreover, the frequency of lethal outcomes increases significantly in correlation with the age of patients and does not depend on the choice of treatment method – surgical or therapeutic.Conclusion: COVID-19 significantly complicates provision of medical care in conditions of the round-the-clock hospital for blood circulatory system diseases. The risks of surgical interventions for circulatory system diseases in combination with COVID-19 are as high as with the use of therapeutic technologies. It is necessary to unify the indications and contraindications to surgical treatment of conditions related to acute coronary syndrome in cases of the presence of such concomitant pathology as COVID-19.

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Sylla, Dr M., Dr M. Cheqboub, Dr M. Tebaa, Pr M. S. Moudouni, Pr M. A. Lakmichi, Pr Z. Dahami et Pr I. Sarf. « mpact of the COVID 19 Pandemic on the Activities of the Urology Department of Arrazi Hospital, Mohammed VI University Hospital, Marrakech ». SAS Journal of Medicine 8, n^o 10 (17 octobre 2022) : 720–27. http://dx.doi.org/10.36347/sasjm.2022.v08i10.011.

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Introduction: The impacts of the COVID-19 pandemic in the urology centers in Morocco are unknown with a lack of data on the evaluation of the level of urological activities per-COVID19, hence, the reasons that motivated us to conduct this study. The main objective of our work is to evaluate the repercussion of the COVID 19 pandemic on the medicosurgical activities of the Urology service of the CHU MOHAMED VI of Marrakech. Patients and Methods: This is a retrospective and descriptive study comparing activities one year before COVID-19 and one year amidst COVID-19. Ranging from March 23, 2019 to March 23, 2020 for the pre COVID-19 period and from March 23, 2020 to March 23, 2021 for the year during COVID-19 period. All patients seen during the study period with a diagnosis of urological pathology whether in the emergency department or admitted directly to the department through the consultation. Data collection was done with data sheets filled in from the consultation, hospitalization and operating room registers. We also used the digital information system Hosix of our hospital. Each patient file included in the study was the subject of an exploitation form established on the basis of the objectives of the study. The analysis and writing of the data were done with the software: Word, Excel and SPSS. Results and Discussion: A total of 771 adult urological procedures were performed during the pre-COVID period and 531 during the per-COVID period, representing an overall reduction in activity of 18.44%. The decrease in activity for scheduled procedures was 34% (543 versus 267) for the year during COVID-19 period. The decrease in emergency activity was 21% (221 Pre-COVID versus 148 during COVID period). IRO was the most common diagnosis during the two study periods, followed by spermatic torsion for patients seen in the emergency department, with respective percentages of 65.9% and 47.8% for the pre-COVID period and 52.2% and 44.1% amidst COVID period. The decreases in...

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Ohniev, V. A., et K. G. Pomohaibo. « DEFINITION OF MEASURES TO REDUCE THE OBESITY LEVEL IN CHILDREN BASED ON RESEARCH RESULTS OF PREVALENCE AND RISK FACTORS ». Вісник соціальної гігієни та організації охорони здоров'я України, n^o 3 (23 décembre 2020) : 51–55. http://dx.doi.org/10.11603/1681-2786.2020.3.11622.

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Purpose: to study prevalence and main risk factors for overweight and obesity in children and adolescents aged 6–17 and develop appropriate prevention measures. Materials and Methods. Bibliographic, statistical and sociological methods. Results. It is noted an insufficient level of registration of obesity among children. During the study it was found that true prevalence of obesity and overweight in children and adolescents in Kharkiv is significantly different from the official statistics in Kharkiv region ((151.0±5.2)‰). 22 factors of risk had a reliable impact on the development of overweight in children and adolescents. The main risk factors for the formation of the overweight were biological and social and hygienic. Based on the results of the research it was proved that the key measures to reduce the prevalence of obesity and its consequences should be aimed at modifying risk factors, namely: changing stereotypes and habitats that contribute to pathology and at improving the quality of health care, basically at the primary level. Thus priority measures for improvement the quality of health care for children and adolescents with obesity should include: mandatory monitoring of body mass index among children from the age of 3 and assessment of the harmony of physical development; introduction of an information system for accounting, monitoring of obesity and overweight and the main risk factors (electronic medical record of the patient); introduction of patient registers at the territorial and regional level; preferential supervision by the family doctor, involvement of all experts; raising public awareness at the group, individual level; timely identification of risk factors, formation of risk groups, organization of dynamic monitoring, creation of differentiated prevention programs and study of public awareness of the main risks of overweight; advanced training of doctors, conducting training seminars on nutrition. Conclusions. Thus, to solve the problem of obesity in children such structures as local governments, educational institutions, healthcare institutions and public organizations should be obligatory involved. Special attention is paid to measures to optimize medical care at the primary level for such children.

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Röcken, C. « Das Amyloid Register Kiel ». Der Pathologe 39, S2 (9 octobre 2018) : 301–5. http://dx.doi.org/10.1007/s00292-018-0515-x.

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Rabenhorst, G., M. Tsokos, F. Freitag et C. Wienegge. « Ein Register für Schilddrüsenerkrankungen ». Der Pathologe 19, n^o 5 (18 septembre 1998) : 361–67. http://dx.doi.org/10.1007/s002920050298.

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Барбова, Н. И., В. В. Егоров, Е. А. Халабуденко et М. С. Стратила. « The results of monitoring of congenital anomalies in the Republic of Moldova for 10 years ». Nauchno-prakticheskii zhurnal «Medicinskaia genetika», n^o 7(216) (30 juillet 2020) : 33–35. http://dx.doi.org/10.25557/2073-7998.2020.07.33-35.

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В статье представлены данные Национального регистра врожденных пороков развития (ВПР). Проведен анализ эпидемиологии ВПР: изучены популяционные частоты всех зарегистрированных пороков и отдельных нозологических форм и их структура, а также динамика частот пороков обязательного учета за период с 2009 по 2018 годы. The article presents the results of monitoring of congenital anomalies of the Republic of Moldova - the national register of Moldova, formed on the basis of the laboratory of prevention of hereditary pathology at the Institute of Mother and Child. The analysis of data for the period from 2009 to 2018. The article presents data on the epidemiology of congenital anomalies: population frequencies of all registered defects and individual nosological forms, the structure of developmental defects in the country, as well as the dynamics of the frequency of defects of mandatory accounting for the analyzed period of time.

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Safronov, O. V., E. A. Kazachkova, E. L. Kazachkov, I. V. Safronovа et G. N. Mshak-Manukyan. « Dynamics of Uterine Blood Flow Parameters in Minimally Invasive Surgeries of the Intrauterine Pathology with the Use of Various Energy Types ». Doctor.Ru 21, n^o 5 (2022) : 75–80. http://dx.doi.org/10.31550/1727-2378-2022-21-5-75-80.

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Study Objective: To analyze the nature of changes in the parameters of uterine blood flow in minimally invasive surgical treatment of intrauterine pathology with the use of the diode laser energy operated in pulsed mode or bipolar energy. Study Design: Retrospective comparative study. Materials and Methods. A retrospective analysis of the reports of the Doppler ultrasound examination of the uterine blood flow in 102 patients who underwent surgery in the period from 2016 till 2020 was conducted to study the dynamics of uterine blood flow parameters in minimally invasive surgeries of intrauterine pathology utilizing various types of energy. Treatment of intrauterine pathology with the use of surgical diode laser in pulsed mode was performed in 60 women (1st group), 42 women were treated with bipolar energy (2nd group). Resistance index (RI) and pulsatility index (PI) in the right and left uterine arteries, arterial perfusion index (API), possibility to register the blood flow in sub-endometrial and endometrial blood vessels were evaluated while studying the uterine blood flow. Study Results. After the surgeries performed with the use of diode laser, the IR and PI remained unchanged statistically significantly more frequently than after the surgical treatment with the use of bipolar energy: 75 and 53.34% vs 30.95 and 33.33%. API statistically significantly more frequently increased in the 1st group (53.33%) and decreased in the 2nd group (66.67%). The blood flow in basal and coiled arteries of the uterus in post-surgery period is registered statistically significantly more often if diode laser was used as compared to the surgeries performed with bipolar energy (43.33 and 41.67% vs 21.43 and 19.05%, respectively). Conclusion. The use of bipolar energy in the treatment of intrauterine pathology leads to more severe uterine blood flow disturbances than surgeries with the use of diode laser. That is why it is reasonable to use the energy of a diode laser in pulsed mode in case of minimally invasive surgical treatment of intrauterine pathology. Keywords: intrauterine pathology, office hysteroscopy, diode laser, bipolar electrode, uterine blood flow.

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