Littérature scientifique sur le sujet « Pancreatic CSC »
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Articles de revues sur le sujet "Pancreatic CSC"
Yang, Zhiyong, Ning Zhao, Jing Cui, Heshui Wu, Jiongxin Xiong et Tao Peng. « Exosomes derived from cancer stem cells of gemcitabine-resistant pancreatic cancer cells enhance drug resistance by delivering miR-210 ». Cellular Oncology 43, no 1 (12 novembre 2019) : 123–36. http://dx.doi.org/10.1007/s13402-019-00476-6.
Texte intégralWalter, Karolin, Eva Rodriguez-Aznar, Monica S. Ventura Ferreira, Pierre-Olivier Frappart, Tabea Dittrich, Kanishka Tiwary, Sabine Meessen et al. « Telomerase and Pluripotency Factors Jointly Regulate Stemness in Pancreatic Cancer Stem Cells ». Cancers 13, no 13 (23 juin 2021) : 3145. http://dx.doi.org/10.3390/cancers13133145.
Texte intégralMalaer, Joseph D., et Porunelloor A. Mathew. « Cancer stem cells inhibit NK cell effector function via PCNA-NKp44 interaction ». Journal of Immunology 202, no 1_Supplement (1 mai 2019) : 134.12. http://dx.doi.org/10.4049/jimmunol.202.supp.134.12.
Texte intégralSmith, Ebony, et Tuan Tran. « Recurrence of Pancreatic Cancer Presenting as Choroidal Metastasis : A Case Report ». Case Reports in Ophthalmology 12, no 3 (25 octobre 2021) : 854–58. http://dx.doi.org/10.1159/000519689.
Texte intégralChen, Yu-Jen, Yu-Chuen Huang, Tung-Hu Tsai et Hui-Fen Liao. « Effect of Wasabi Component 6-(Methylsulfinyl)hexyl Isothiocyanate and Derivatives on Human Pancreatic Cancer Cells ». Evidence-Based Complementary and Alternative Medicine 2014 (2014) : 1–6. http://dx.doi.org/10.1155/2014/494739.
Texte intégralMalaer, Joseph D., et Porunelloor A. Mathew. « Pancreatic and colon cancer stem cells escape NK cell effector function via PCNA–NKp44 interaction ». Journal of Immunology 204, no 1_Supplement (1 mai 2020) : 88.16. http://dx.doi.org/10.4049/jimmunol.204.supp.88.16.
Texte intégralSasaki, Norihiko, Kazumi Hirano, Yuuki Shichi, Fujiya Gomi, Hisashi Yoshimura, Akira Matsushita, Masashi Toyoda et Toshiyuki Ishiwata. « Gp130-Mediated STAT3 Activation Contributes to the Aggressiveness of Pancreatic Cancer through H19 Long Non-Coding RNA Expression ». Cancers 14, no 9 (19 avril 2022) : 2055. http://dx.doi.org/10.3390/cancers14092055.
Texte intégralAlcalá, Sonia, Paola Martinelli, Patrick C. Hermann, Christopher Heeschen et Bruno Sainz. « The Anthrax Toxin Receptor 1 (ANTXR1) Is Enriched in Pancreatic Cancer Stem Cells Derived from Primary Tumor Cultures ». Stem Cells International 2019 (2 mai 2019) : 1–13. http://dx.doi.org/10.1155/2019/1378639.
Texte intégralCash, Timothy P., Sonia Alcalá, María del Rosario Rico-Ferreira, Elena Hernández-Encinas, Jennifer García, María Isabel Albarrán, Sandra Valle et al. « Induction of Lysosome Membrane Permeabilization as a Therapeutic Strategy to Target Pancreatic Cancer Stem Cells ». Cancers 12, no 7 (4 juillet 2020) : 1790. http://dx.doi.org/10.3390/cancers12071790.
Texte intégralGuo, Yichen, Yinan Jiang, J. Bart Rose, Ganji Purnachandra Nagaraju, Renata Jaskula-Sztul, Anita B. Hjelmeland, Adam W. Beck, Herbert Chen et Bin Ren. « Protein Kinase D1 Signaling in Cancer Stem Cells with Epithelial-Mesenchymal Plasticity ». Cells 11, no 23 (1 décembre 2022) : 3885. http://dx.doi.org/10.3390/cells11233885.
Texte intégralThèses sur le sujet "Pancreatic CSC"
RITELLI, Rossana. « Generating a pancreatic cancer mouse model : from Cancer Stem Cells to in vivo imaging strategies ». Doctoral thesis, Università degli Studi di Verona, 2010. http://hdl.handle.net/11562/344615.
Texte intégralBackground: Pancreatic cancer remains a highly aggressive and not curable cancer in spite of the ample research in the last decades. Since conventional treatment approaches have not satisfactory effects because they don’t result in a significant improvement of the disease outcome, an effective research system is still strongly needed, in order to accurately predict the clinical efficacy of novel compounds developed for pancreatic cancer treatment. Aim: the aim of the current study is to contribute to the generation of a complete and straightforward system useful for the identification and pre-clinic screening of novel drug for the treatment pancreatic cancer. This system should provide the techniques, the protocols and a pancreatic cancer model suitable firstly for in vitro high-throughput compounds screening and then for in vivo validation of the selected molecules. Results: findings previously obtained in our laboratory have already demonstrate potential stemlike behavior of Panc-1 cells growing as 3-dimensional spheres (Panc1-spheres), isolated from adherent Panc-1 cell line. In this study we continued with the in vivo characterization of Panc-1 spheres because we used them as pancreatic cancer cell line model in the compounds screening system we are generating. So, we performed subcutaneus and orthotopical injections in nude mice with adherent Panc1 and Panc1-spheres cells. Tumor growths were followed using MRI. In order to deepen the characterization of Panc1-spheres, we also studied EMT on tumors derived from this experiment such as in vitro in both cell lines. Moreover, we observed that an improvement of imaging strategies was actually needed, in order to better control above all the formation of small masses as metastasis and early primary tumors, since MRI was not sufficient when used alone. For this reason, we also decided to focus our attention to the most important non-invasive small animalimaging modalities available today, in particular MRI, Micro-Ultrasound (US) and In Vivo Optical Imaging. Then, we correlated these techniques, arriving to the point to have an “imaging protocol”, able to offset some of the limitation of each modality when used alone, to be used in the compounds screening system we would like to generate. Conclusion: Our findings have demonstrated that the pancreatic cancer spheres are more than just cancer stem-like cells. Our mouse model, established with Sphere-growing cells, may be used for the testing of novel compounds specifically designed to target this stem-like compartment, resistant to standard chemotherapies. A combined imaging approach, with combine MRI, Optical imaging and US, in this contest become extremely important, in order to follow primary tumor sizes and metastasis detection before and after the treatment with novel compounds.
D'AGOSTO, SABRINA LUIGIA. « EVALUATION OF CANCER-STEM CELLS IN DIFFERENT MODELS OF PANCREATIC DUCTAL ADENOCARCINOMA ». Doctoral thesis, 2017. http://hdl.handle.net/11562/960930.
Texte intégralChapitres de livres sur le sujet "Pancreatic CSC"
Alvina, Fidelia B., Arvin M. Gouw et Anne Le. « Cancer Stem Cell Metabolism ». Dans The Heterogeneity of Cancer Metabolism, 161–72. Cham : Springer International Publishing, 2021. http://dx.doi.org/10.1007/978-3-030-65768-0_12.
Texte intégralY. Liu, Alvin, Tatjana Crnogorac-Jurcevic, James J. Lai et Hung-Ming Lam. « Antibody Therapy Targeting Cancer-Specific Cell Surface Antigen AGR2 ». Dans Advances in Precision Medicine Oncology. IntechOpen, 2021. http://dx.doi.org/10.5772/intechopen.96492.
Texte intégralTüysüz, Umut. « Choledochal Cysts ». Dans Biliary Tract - Review and Recent Progress [Working Title]. IntechOpen, 2022. http://dx.doi.org/10.5772/intechopen.109023.
Texte intégralActes de conférences sur le sujet "Pancreatic CSC"
Arima, Kota, Takatsugu Ishimoto, Hirohisa Okabe, Yuki Kitano, Risa Inoue, Kensuke Yamamura, Takayoshi Kaida et al. « Abstract 3350 : Verification of mechanism that CSC markers are implicated in poor prognosis for pancreatic ductal adenocarcinoma ». Dans Proceedings : AACR 107th Annual Meeting 2016 ; April 16-20, 2016 ; New Orleans, LA. American Association for Cancer Research, 2016. http://dx.doi.org/10.1158/1538-7445.am2016-3350.
Texte intégralAvan, Amir, Karl Quint, Francesco Nicolini, Mina Maftouh, Niccola Funel, Godefridus J. Peters et Elisa Giovannetti. « Abstract A46 : c-MET as a potential therapeutic target in pancreatic cancer : Implications in cancer-stem-like cell (CSC) population and gemcitabine resistance in pancreatic cancer. » Dans Abstracts : AACR Special Conference on Pancreatic Cancer : Progress and Challenges ; June 18-21, 2012 ; Lake Tahoe, NV. American Association for Cancer Research, 2012. http://dx.doi.org/10.1158/1538-7445.panca2012-a46.
Texte intégralBossard, Carine, Nathalia Cruz, Brian Eastman, Chi-Ching Mak, Sunil KC, Betty Tam, Timothy Phalen et Steven Cha. « Abstract C08 : SM08502, a novel, small-molecule CDC-like kinase (CLK) inhibitor, demonstrates activity against cancer stem cell (CSC)-enriched pancreatic cancer cells and suppresses stemness in vitro ». Dans Abstracts : AACR Special Conference on Pancreatic Cancer : Advances in Science and Clinical Care ; September 6-9, 2019 ; Boston, MA. American Association for Cancer Research, 2019. http://dx.doi.org/10.1158/1538-7445.panca19-c08.
Texte intégralKim, Edward J., Gazala N. Khan, Kent Griffith, Joel Greenson, Naoko Takebe, Mark Zalupski et Diane Simeone. « Abstract A40 : Cancer stem cells (CSC) and inhibition of hedgehog (Hh) pathway signaling in advanced pancreatic cancer : GDC-0449 in combination with gemcitabine (Gem). » Dans Abstracts : AACR Special Conference on Pancreatic Cancer : Progress and Challenges ; June 18-21, 2012 ; Lake Tahoe, NV. American Association for Cancer Research, 2012. http://dx.doi.org/10.1158/1538-7445.panca2012-a40.
Texte intégralLi, Rui, et Yaolong Qi. « Network-based analysis of important subnetworks during pancreatic cancer development ». Dans 2016 35th Chinese Control Conference (CCC). IEEE, 2016. http://dx.doi.org/10.1109/chicc.2016.7554844.
Texte intégralDe Gaetano, Andrea, Claudio Gaz, Claudio Gori Giorgi et Pasquale Palumbo. « An islet population model of pancreatic insulin production ». Dans 2013 IEEE 52nd Annual Conference on Decision and Control (CDC). IEEE, 2013. http://dx.doi.org/10.1109/cdc.2013.6760396.
Texte intégralGong, Haijun, Paolo Zuliani, Qinsi Wang et Edmund M. Clarke. « Formal analysis for logical models of pancreatic cancer ». Dans 2011 50th IEEE Conference on Decision and Control and European Control Conference (CDC-ECC 2011). IEEE, 2011. http://dx.doi.org/10.1109/cdc.2011.6161052.
Texte intégralGeng, Yuchen, et Weimin Zhou. « Image Super-Resolution Reconstruction of Pancreatic Carcinoma Based on Edge Repair Generative Adversarial Network ». Dans 2022 41st Chinese Control Conference (CCC). IEEE, 2022. http://dx.doi.org/10.23919/ccc55666.2022.9901818.
Texte intégralBossard, Carine, Nathalia Cruz, Brian Eastman, Chi-Ching Mak, K. C. Sunil, Betty Tam, Gail Bucci, Josh Stewart, Timothy Phalen et Steven Cha. « Abstract A02 : SM08502, a novel, small-molecule CDC-like kinase (CLK) inhibitor, downregulates the Wnt signaling pathway and demonstrates antitumor activity in pancreatic cancer cell lines and in vivo xenograft models ». Dans Abstracts : AACR Special Conference on Pancreatic Cancer : Advances in Science and Clinical Care ; September 6-9, 2019 ; Boston, MA. American Association for Cancer Research, 2019. http://dx.doi.org/10.1158/1538-7445.panca19-a02.
Texte intégralBossard, Carine, Igor Astsaturov, Nathalia Cruz, Brian Eastman, Chi-Ching Mak, K. C. Sunil, Betty Tam et al. « Abstract C09 : Inhibition of tumor growth and post-treatment regrowth by SM08502, a novel, small-molecule CDC-like kinase (CLK) inhibitor, in combination with standard of care in pancreatic cancer models ». Dans Abstracts : AACR Special Conference on Pancreatic Cancer : Advances in Science and Clinical Care ; September 6-9, 2019 ; Boston, MA. American Association for Cancer Research, 2019. http://dx.doi.org/10.1158/1538-7445.panca19-c09.
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