Littérature scientifique sur le sujet « Oriented cell division »
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Articles de revues sur le sujet "Oriented cell division"
Strutt, David. « Organ Shape : Controlling Oriented Cell Division ». Current Biology 15, no 18 (septembre 2005) : R758—R759. http://dx.doi.org/10.1016/j.cub.2005.08.053.
Texte intégralCastanon, I., et M. González-Gaitán. « Oriented cell division in vertebrate embryogenesis ». Current Opinion in Cell Biology 23, no 6 (décembre 2011) : 697–704. http://dx.doi.org/10.1016/j.ceb.2011.09.009.
Texte intégralDewey, Evan, Danielle Taylor et Christopher Johnston. « Cell Fate Decision Making through Oriented Cell Division ». Journal of Developmental Biology 3, no 4 (14 décembre 2015) : 129–57. http://dx.doi.org/10.3390/jdb3040129.
Texte intégralHart, Kevin C., Jiongyi Tan, Kathleen A. Siemers, Joo Yong Sim, Beth L. Pruitt, W. James Nelson et Martijn Gloerich. « E-cadherin and LGN align epithelial cell divisions with tissue tension independently of cell shape ». Proceedings of the National Academy of Sciences 114, no 29 (3 juillet 2017) : E5845—E5853. http://dx.doi.org/10.1073/pnas.1701703114.
Texte intégralde Keijzer, Jeroen, Alejandra Freire Rios et Viola Willemsen. « Physcomitrium patens : A Single Model to Study Oriented Cell Divisions in 1D to 3D Patterning ». International Journal of Molecular Sciences 22, no 5 (5 mars 2021) : 2626. http://dx.doi.org/10.3390/ijms22052626.
Texte intégralWyatt, Tom P. J., Andrew R. Harris, Maxine Lam, Qian Cheng, Julien Bellis, Andrea Dimitracopoulos, Alexandre J. Kabla, Guillaume T. Charras et Buzz Baum. « Emergence of homeostatic epithelial packing and stress dissipation through divisions oriented along the long cell axis ». Proceedings of the National Academy of Sciences 112, no 18 (23 avril 2015) : 5726–31. http://dx.doi.org/10.1073/pnas.1420585112.
Texte intégralMoyle, Louise A., Richard Y. Cheng, Haijiao Liu, Sadegh Davoudi, Silvia A. Ferreira, Aliyah A. Nissar, Yu Sun, Eileen Gentleman, Craig A. Simmons et Penney M. Gilbert. « Three-dimensional niche stiffness synergizes with Wnt7a to modulate the extent of satellite cell symmetric self-renewal divisions ». Molecular Biology of the Cell 31, no 16 (21 juillet 2020) : 1703–13. http://dx.doi.org/10.1091/mbc.e20-01-0078.
Texte intégralScepanovic, Gordana, et Rodrigo Fernandez-Gonzalez. « Oriented Cell Division : The Pull of the Pole ». Developmental Cell 47, no 6 (décembre 2018) : 686–87. http://dx.doi.org/10.1016/j.devcel.2018.11.040.
Texte intégralWalker, Keely L., et Laurie G. Smith. « Investigation of the role of cell-cell interactions in division plane determination during maize leaf development through mosaic analysis of the tangled mutation ». Development 129, no 13 (1 juillet 2002) : 3219–26. http://dx.doi.org/10.1242/dev.129.13.3219.
Texte intégralConcha, M. L., et R. J. Adams. « Oriented cell divisions and cellular morphogenesis in the zebrafish gastrula and neurula : a time-lapse analysis ». Development 125, no 6 (15 mars 1998) : 983–94. http://dx.doi.org/10.1242/dev.125.6.983.
Texte intégralThèses sur le sujet "Oriented cell division"
Darby, Daniel. « A mechanism of oriented cell division underlying cardiac chamber expansion ». Electronic Thesis or Diss., Sorbonne université, 2019. http://www.theses.fr/2019SORUS666.
Texte intégralThe development of the heart is an intricate process both physically and genetically which requires regulation on many levels. Perturbations of this cardiogenic programme often has potent consequence on the organ and this is evident from the 1% incidence in births which are affected by a congenital heart disease (CHD). CHDs, such as cardiomyopathies, affect the architecture of the cardiac muscle, which is vital to the heartsfunction. The shape of the ventricular walls is particularly important to their function in terms of both defining the shape of the ventricular chambers and in establishing an appropriate myofiber architecture for efficient contractions (Meilhac et al., 2003). Previous work in the lab has provided insight into how this is achieved in the ventricles. It was found, through clonal analysis, that oriented tissue growth underlies cardiac chamber expansion (Meilhac et al., 2004). Analysis of earlier stages of the embryonic heart found regional coordination of cell divisions which preconfigured the myofiber architecture of the adult heart (Le Garrec et al., 2013). These studies suggest that oriented cell division plays an important role in sculpting the heart. However a mechanism by which this is regulated has yet to be established in the expanding ventricular chambers. In this project we use a combination of transcriptomic analysis, 3D cell segmentation, embryo culture experiments and molecular interference to investigate a mechanism for oriented cell division. Using bulk RNAseq we identified the NuMA:GPSM apparatus, the Planar Cell Polarity pathway and the integrin mechano-sensing pathway as candidates for further analysis. In combination with the transcriptomic analysis we wanted to identify if cells in the expanding ventricles were behaving according to Hertwig’s rule. To do this we have established CUBIC clearing and three dimensional lightsheet microscopy along with an automatic cell segmentation method to quantify cell elongations in the cardiac chambers. By comparing the elongation ratio of the cell to the detected axes of division the tools and approaches described above will enable us to identify if coordination existed between the two and if this was regionally specific. To analyse the impact of cardiac contractions on oriented cell division we established embryo culture experiment conditions paired with pharmaceutical interference of contractions. Preliminary results indicate that both an increase and decrease of contraction rate affects the shape of the heart. Finally, we will target the three pathways mentioned above with dominant negative proteins in chimeric hearts to dissect the molecular pathways. The outcome of this research will have potential applications in tissue engineering therapies targeting the heart
Gallini, S. « MOLECULAR CONTRIBUTION OF THE AURORA-A KINASE AND THE JUNCTIONAL PROTEIN AFADIN TO ORIENTED CELL DIVISIONS ». Doctoral thesis, Università degli Studi di Milano, 2016. http://hdl.handle.net/2434/354581.
Texte intégralStrauss, Bernhard. « Oriented cell divisions in the Xenopus blastula ». Thesis, University of Cambridge, 2006. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.614211.
Texte intégralFrancou, Alexandre. « Epithelial properties of Second Heart Field cardiac progenitor cells ». Thesis, Aix-Marseille, 2015. http://www.theses.fr/2015AIXM4062.
Texte intégralA major part of the heart is formed by progenitor cells called the second heart field, that contribute to rapid elongation of the heart tube. Defects in second heart field development leads to congenital heart malformations. Second heart field cells are localised in pharyngeal mesoderm in the dorsal pericardial wall. This study focuses on the epithelial properties of second heart field cells and first shows that these progenitors in the dorsal pericardial wall are epithelial and polarised, and form dynamic basal filopodia. Deletion of the transcription factor Tbx1 perturbs epithelial polarity and filopodia formation and upregulates the apical determinant aPKCζ. Treatment with an activator of aPKCζ reveals that epithelial integrity, polarity and basal filopodia are coupled to the progenitor status of second heart field cells. Next we evaluated planar polarity of second heart field cells in the dorsal pericardial wall. Cells are anisotropic, being stretched and elongated on an axis directed towards the arterial pole. This stretch results in oriented epithelial tension revealed by polarised actomyosin accumulation through a negative feedback loop. In the absence of cell addition to the cardiac poles oriented tension is absent. We identified a posterior region in the epithelium with high tension, elevated proliferation and a high level of active YAP/TAZ that may act as relay between tension and proliferation. Oriented tension orients the axis of cell division and the growth of the tissue on an axis toward the arterial pole, further promoting addition of the tissue to the pole. Biomechanical feedback may thus be an important driver of heart tube elongation
Di, Pietro Maria Florencia. « Systematic assessment of the role of Dynein regulators in oriented cell divisions by live RNAi screen in a novel vertebrate model of spindle orientation ». Thesis, Paris 6, 2016. http://www.theses.fr/2016PA066405/document.
Texte intégralMitotic spindle orientation is involved in cell fate decisions, tissue homeostasis and morphogenesis. In many contexts, spindle orientation is controlled by the LGN molecular complex, whose subcortical localization determines the site of recruitment of the dynein motor which exerts forces on astral microtubules orienting the spindle. In vertebrates, there is missing information about the molecules regulating the formation of the complex and those working downstream of it. This prompted us to screen for new regulators of vertebrate spindle orientation. For this, I developed a novel model of spindle orientation specifically controlled by the LGN complex. Using this model, I performed a live siRNA screen testing 110 candidates including molecular motors for their function in spindle orientation. Remarkably, this screen revealed that specific dynein regulators contribute differentially to spindle orientation. Moreover, I found that an uncharacterized member of the dynactin complex, the actin capping protein CAPZ-B, is a strong regulator of spindle orientation. Analyses of CAPZ-B function in cultured cells showed that CAPZ-B regulates spindle orientation independently of its classical role in modulating actin dynamics. Instead, CAPZ-B controls spindle orientation by modulating the localization/activity of the dynein/dynactin complexes and the dynamics of spindle microtubules. Finally, we demonstrated that CAPZ-B regulates planar spindle orientation in vivo in the chick embryonic neuroepithelium. I expect that my work will contribute to the understanding of dynein function during vertebrate spindle orientation and will open the path for new investigations in the field
Di, Pietro Maria Florencia. « Systematic assessment of the role of Dynein regulators in oriented cell divisions by live RNAi screen in a novel vertebrate model of spindle orientation ». Electronic Thesis or Diss., Paris 6, 2016. https://accesdistant.sorbonne-universite.fr/login?url=https://theses-intra.sorbonne-universite.fr/2016PA066405.pdf.
Texte intégralMitotic spindle orientation is involved in cell fate decisions, tissue homeostasis and morphogenesis. In many contexts, spindle orientation is controlled by the LGN molecular complex, whose subcortical localization determines the site of recruitment of the dynein motor which exerts forces on astral microtubules orienting the spindle. In vertebrates, there is missing information about the molecules regulating the formation of the complex and those working downstream of it. This prompted us to screen for new regulators of vertebrate spindle orientation. For this, I developed a novel model of spindle orientation specifically controlled by the LGN complex. Using this model, I performed a live siRNA screen testing 110 candidates including molecular motors for their function in spindle orientation. Remarkably, this screen revealed that specific dynein regulators contribute differentially to spindle orientation. Moreover, I found that an uncharacterized member of the dynactin complex, the actin capping protein CAPZ-B, is a strong regulator of spindle orientation. Analyses of CAPZ-B function in cultured cells showed that CAPZ-B regulates spindle orientation independently of its classical role in modulating actin dynamics. Instead, CAPZ-B controls spindle orientation by modulating the localization/activity of the dynein/dynactin complexes and the dynamics of spindle microtubules. Finally, we demonstrated that CAPZ-B regulates planar spindle orientation in vivo in the chick embryonic neuroepithelium. I expect that my work will contribute to the understanding of dynein function during vertebrate spindle orientation and will open the path for new investigations in the field
Livres sur le sujet "Oriented cell division"
Kühn, Wolfgang, et Gerd Walz. The molecular basis of ciliopathies and cyst formation. Sous la direction de Neil Turner. Oxford University Press, 2015. http://dx.doi.org/10.1093/med/9780199592548.003.0303.
Texte intégralChapitres de livres sur le sujet "Oriented cell division"
Piano, Fabio, et Kenneth Kemphues. « Genetic analysis of intrinsically asymmetrical cell division ». Dans Cell Polarity, 240–68. Oxford University PressOxford, 2000. http://dx.doi.org/10.1093/oso/9780199638031.003.0008.
Texte intégralWolpert, Lewis, Cheryll Tickle, Alfonso Martinez Arias, Peter Lawrence et James Locke. « Plant development ». Dans Principles of Development. Oxford University Press, 2019. http://dx.doi.org/10.1093/hesc/9780198800569.003.0013.
Texte intégralLeón-Mejía, Grethel, Alvaro Miranda Guevara, Ornella Fiorillo Moreno et Carolina Uribe Cruz. « Cytotoxicity as a Fundamental Response to Xenobiotics ». Dans Cytotoxicity - New Insights into Toxic Assessment. IntechOpen, 2021. http://dx.doi.org/10.5772/intechopen.96239.
Texte intégralPidoux, Alison L., et Robin C. Allshire. « The structure of yeast centromeres and telomeres and the role of silent heterochromatin ». Dans The Yeast Nucleus, 212–45. Oxford University PressOxford, 2000. http://dx.doi.org/10.1093/oso/9780199637737.003.0007.
Texte intégralDavies, Jamie A. « Morphogenesis by Orientated Cell Division ». Dans Mechanisms of Morphogenesis, 307–23. Elsevier, 2013. http://dx.doi.org/10.1016/b978-0-12-391062-2.00023-1.
Texte intégralDavies, Jamie A. « Morphogenesis by Orientated Cell Division ». Dans Mechanisms of Morphogenesis, 361–77. Elsevier, 2023. http://dx.doi.org/10.1016/b978-0-323-99965-6.00002-6.
Texte intégralCarlos Valdés Hernández, Roberto, Juan Gabriel Lopez Hernandez, Adelaida Figueroa Villanueva et Vidblain Amaro Ortega. « Impact of ICT to Improve of the Manufacturing in a SME Biomedical of Mexicali, Mexico ». Dans Concepts, Applications and Emerging Opportunities in Industrial Engineering. IntechOpen, 2021. http://dx.doi.org/10.5772/intechopen.93585.
Texte intégralActes de conférences sur le sujet "Oriented cell division"
Hashimoto, Shigehiro, Hiroki Yonezawa et Ryuya Ono. « Cell Activity Change After Division Under Wall Shear Stress Field ». Dans ASME 2021 International Mechanical Engineering Congress and Exposition. American Society of Mechanical Engineers, 2021. http://dx.doi.org/10.1115/imece2021-69689.
Texte intégralHashimoto, Shigehiro, et Takashi Yokomizo. « Tracings of Interaction Between Myoblasts Under Shear Flow in Vitro ». Dans ASME 2021 Fluids Engineering Division Summer Meeting. American Society of Mechanical Engineers, 2021. http://dx.doi.org/10.1115/fedsm2021-65203.
Texte intégralPiqueras, Pedro, Benjamín Pla, Enrique José Sanchis et André Aronis. « Ammonia Slip Estimation Based on ASC Control-Oriented Modelling And OBD NOx Sensor Cross-Sensitivity Analysis ». Dans ASME 2021 Internal Combustion Engine Division Fall Technical Conference. American Society of Mechanical Engineers, 2021. http://dx.doi.org/10.1115/icef2021-67710.
Texte intégralSpring, Peter, Lino Guzzella et Christopher H. Onder. « Optimal Control Strategy for a Pressure-Wave Supercharged SI Engine ». Dans ASME 2003 Internal Combustion Engine Division Spring Technical Conference. ASMEDC, 2003. http://dx.doi.org/10.1115/ices2003-0645.
Texte intégralMoser, Sean, Simona Onori et Mark Hoffman. « Design and Experimental Validation of a Spatially Discretized, Control-Oriented Temperature Model for a Ceria-Washcoated Gasoline Particulate Filter ». Dans ASME 2018 Internal Combustion Engine Division Fall Technical Conference. American Society of Mechanical Engineers, 2018. http://dx.doi.org/10.1115/icef2018-9687.
Texte intégralRozenfeld, A., Y. Kozak, T. Rozenfeld et G. Ziskind. « A Novel Double-Pipe Heat Storage Unit ». Dans ASME 2016 Heat Transfer Summer Conference collocated with the ASME 2016 Fluids Engineering Division Summer Meeting and the ASME 2016 14th International Conference on Nanochannels, Microchannels, and Minichannels. American Society of Mechanical Engineers, 2016. http://dx.doi.org/10.1115/ht2016-7394.
Texte intégralRapports d'organisations sur le sujet "Oriented cell division"
Sadot, Einat, Christopher Staiger et Zvi Kam Weizmann. functional genomic screen for new plant cytoskeletal proteins and the determination of their role in actin mediated functions and guard cells regulation. United States Department of Agriculture, janvier 2003. http://dx.doi.org/10.32747/2003.7587725.bard.
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