Littérature scientifique sur le sujet « Organic Synthessis »

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Articles de revues sur le sujet "Organic Synthessis"

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Dai, Mingji, Xinpei Cai et Yu Bai. « Total Syntheses of Spinosyn A ». Synlett 29, no 20 (7 septembre 2018) : 2623–32. http://dx.doi.org/10.1055/s-0037-1610249.

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Spinosyn A is an important polycyclic natural product with impressive insecticidal activity and has been used worldwide in agriculture as the major component of Spinosad. Herein, four chemical total syntheses of spinosyn A are summarized. Its biosynthesis and a chemoenzymatic total synthesis are discussed as well.1 Biosynthesis2 The Evans Synthesis3 The Paquette Synthesis4 The Roush Synthesis5 The Liu Synthesis6 The Dai Synthesis7 Conclusions
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Trofimov, B. A., et E. Yu Schmidt. « SUPERBASES IN ORGANIC SYNTHESIS ». Chemical Problems 20, no 4 (2022) : 325–40. http://dx.doi.org/10.32737/2221-8688-2022-3-325-340.

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In this concise review, an emphasis is laid on the important role of superbases as catalysts and reagents in organic synthesis that so far remain underestimated. Diverse approaches to understand the superbasicity phenomenon are considered and the definition of superbase is given. Typical compositions of most widespread superbase systems are systematized and tabulated. The representative classic organic reactions assisted by superbases are surveyed.
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Huang, Jianhui, Caifeng Li, Liu Liu et Xuegang Fu. « Norbornene in Organic Synthesis ». Synthesis 50, no 15 (25 juin 2018) : 2799–823. http://dx.doi.org/10.1055/s-0037-1610143.

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The norbornene skeleton possesses an alkene functionality with a fixed conformation, and represents unique reactivity. The use of norbornene and analogues as substrates is overviewed; reactivities are discussed as well as the role of norbornenes as ligands assisting modern organic transformations.1 Introduction2 Synthesis of Substituted Norbornenes2.1 Preparation of Functionalized Norbornenes by Deprotonation and Substitution Reactions2.2 Preparation of Functionalized Norbornenes under Palladium-Catalyzed­ Reaction Conditions2.3 Alkylation of Norbornene2.4 Multistep Synthesis3 Synthesis of Substituted Norbornanes3.1 Three-Membered-Ring Formation3.2 Formation of Four-Membered Rings3.3 Five- and Six-Membered Ring Formation3.4 Syntheses of Difunctionalized Norbornanes4 Synthesis of Cyclopentanes4.1 Oxidation Reactions4.2 Ring-Opening Cross Metathesis (ROCM)4.3 Ring-Opening Metathesis Polymerization (ROMP)4.4 Palladium-Catalyzed Ring-Opening of Norbornene5 Norbornene-Mediated Reactions5.1 Palladium Insertion into Carbon–Halide Bonds5.2 Palladium Insertion into N–H and C–H Bonds5.3 Norbornene as Ligand in Mediated Reactions6 Conclusion
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Tatrishvili, Tamara, et Omar Mukbaniani. « Cyclic Silicon Organic Copolymers : Synthesis and Investigation. Review ». Chemistry & ; Chemical Technology 18, no 2 (14 juin 2024) : 131–42. http://dx.doi.org/10.23939/chcht18.02.131.

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This paper considers the synthesis and investigation of cyclic silicon-organic polymers with mono- and polycyclic fragments in the side chain. For obtaining monocyclic polymers, the hydrosilylation reaction of 1-hydro-3-vinylhexamethylcyclotetrasiloxane was used. The reaction was conducted in a CCl4 solution at 75°C in the presence of Speier’s catalyst (H2PtCl6  6H2O) to produce a viscous-flow at room temperature polymer. The polymers were studied by NMR spectroscopy. Poly(carbosiloxane) with cyclic fragments in the methyl-siloxane backbone was synthesized by the hydride polyaddition of divinylorganocyclosiloxane with dihydrodimethylsiloxane. A semi-quantitative assessment conducted using NMR spectroscopy revealed the ratio of isomeric 1,3- and 1,5-cyclic structures as 1:1. X-ray diffraction studies indicated that copolymers are single-phase amorphous systems. Also, in the review, synthesis and studies of carbosiloxane copolymers containing flexible dimethylsiloxane and decaorganotricyclodecasiloxane fragments in the backbone are discussed. Hydride polyaddition of divinyl-containing compounds was carried out for -dihydridedimethylsiloxanes of various lengths. The synthesized copolymers were characterized by the X-ray diffraction method and TGA.
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Chabukswar, Vasant, Sanjay Bhavsar et Amit Horne. « Organic Synthesis and Characterization of Electrically Conducting Poly(o-Toluidine) Doped with Organic Acid ». Chemistry & ; Chemical Technology 5, no 1 (15 mars 2011) : 37–40. http://dx.doi.org/10.23939/chcht05.01.037.

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Fang, Zhang, et Yu Yang. « Research Progress of Application of Porous Polymer in Energy Storage ». Advanced Materials Research 621 (décembre 2012) : 27–30. http://dx.doi.org/10.4028/www.scientific.net/amr.621.27.

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Nowadays, one of the research emphases in clean energy field is to apply porous polymer as energy storage media to capture and save abundant energy. Researches in this area focus on theoretical methods and syntheses of new materials. Researches on theoretical methods include investigations on mechanical strength, characteristic of heat and mass transfer, internal structure and hydrophilicity of materials using mathematical, physical and chemical methods. Syntheses of new materials include synthesis of porous carbon and porous metal organic frameworks materials and construction of battery structure use polymer organics as matrix.
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Yevchuk, Iryna, Oksana Demchyna, Viktoriya Kochubey, Hanna Romaniuk et Zenoviya Koval. « Synthesis and Characterization of Organic-Inorganic Membranes Containing Sulphogroups ». Chemistry & ; Chemical Technology 7, no 1 (10 mars 2013) : 89–93. http://dx.doi.org/10.23939/chcht07.01.089.

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García-Perulero, I., S. Murcia-Mascarós, J. Rubio et J. L. Oteo. « Síntesis y caracterización de materiales híbridos orgánico-inorgánicos de APS/PDMS ». Boletín de la Sociedad Española de Cerámica y Vidrio 42, no 6 (30 décembre 2003) : 389–96. http://dx.doi.org/10.3989/cyv.2003.v42.i6.627.

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Sharma, Upendra, Inder Kumar et Rakesh Kumar. « Recent Advances in the Regioselective Synthesis of Indoles via C–H Activation/Functionalization ». Synthesis 50, no 14 (28 mai 2018) : 2655–77. http://dx.doi.org/10.1055/s-0037-1609733.

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Indole is an important heterocyclic motif that occurs ubiquitously in bioactive natural products and pharmaceuticals. Immense efforts have been devoted to the synthesis of indoles starting from the Fisher indole synthesis to the recently developed C–H activation/functionalization-based methods. Herein, we have reviewed the progress made on the regioselective synthesis of functionalized indoles, including 2-substituted, 3-substituted and 2,3-disusbstituted indoles, since the year 2010.1 Introduction2 Metal-Catalyzed Synthesis of 2-Substituted Indoles3 Metal-Catalyzed Synthesis of 3-Substituted Indoles4 Metal-Free Synthesis of 3-Substituted Indoles5 Metal-Catalyzed 2,3-Disubstituted Indole Synthesis5.1 Metal-Catalyzed Intramolecular 2,3-Disubstituted Indole Synthesis5.2 Metal-Catalyzed Intermolecular 2,3-Disubstituted Indole Synthesis6 Metal-Free 2,3-Disubstituted Indole Synthesis6.1 N-Protected 2,3-Disubstituted Indole Synthesis6.2 N-Unprotected 2,3-Disubstituted Indole Synthesis7 Applications8 Summary and Outlook
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Wang, Yi, Han Ding et Ge Ging Xu. « Computer Aided Organic Synthesis Based on Graph Grammars ». Applied Mechanics and Materials 411-414 (septembre 2013) : 227–30. http://dx.doi.org/10.4028/www.scientific.net/amm.411-414.227.

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Traditionally, computer aided organic synthesis is based on the one-dimensional string model that employs string grammars to tackle the structure of molecular; the processing of organic reactions, and the establishment of the knowledge bases and file systems. Because of the limitations of one-dimensional method for tackling two-dimensional issues like organic syntheses, this paper presents a method for computer aided organic synthesis based on two-dimensional graph grammars. The method could apply the basic principle of the graph grammars to effectively and efficiently solve organic synthesis problems.
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Thèses sur le sujet "Organic Synthessis"

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Paradis, Michel 1976. « The design and synthessis of platinum-based DNA intercalators / ». Thesis, McGill University, 2000. http://digitool.Library.McGill.CA:80/R/?func=dbin-jump-full&object_id=31523.

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Over the past years, considerable attention has focused on the synthesis of small complexes that can bind and react at specific DNA sequences. This understanding of how to target DNA sites with specificity becomes important for nucleotide probing and novel chemotherapeutics.
Inert and stable transition-metal complexes are already being used for this purpose. Square planar platinum (II) complexes containing an aromatic heterocyclic ligand can insert and stack between the double helix base pairs. Two known ligands, DPPZ and phi, do intercalate DNA when chelating ruthenium, rhodium, or osmium.
Here are presented the syntheses of [Pt(NH3)2DPPZ](CF 3SO3)2, [Pt(en)DPPZ](CF3SO3) 2, [Pt(phen)DPPZ](CF3SO3)2, [Pt(Me 2bpy)DPPZ](CF3SO3)2, and [Pt(phendione)DPPZ](CF 3SO3)2, and the attempted syntheses of [Pt(en)phi](PF 6)2 and [Pt(phen)phi](PF6)2. The binding constants of [Pt(NH3)2DPPZ](CF3SO3) 2 and [Pt(en)DPPZ](CF3SO3)2 to calf thymus DNA have been determined. The knowledge coming from the synthetic strategy to obtain monomers has allowed the synthesis of a platinum-based dimer, [(DPPZ)Pt{DPPZ(11-11 ')DPPZ}Pt(DPPZ)](CF3SO3)4, having two intercalative DPPZ ends. We hope that this bis-intercalator will bring into close proximity two DNA strands.
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Phung, Bich Tuyen. « Etude de la sélectivité dans la réaction de Buchner ». Electronic Thesis or Diss., Université Grenoble Alpes, 2024. https://theses.hal.science/tel-04651531.

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Le travail présenté dans ce manuscrit est divisé en deux grandes parties. Dans un premier temps, une étude sera présentée sur des problème de chimiosélectivité observés lors de la réaction de transfert de carbène. Des composés diazo différemment substitués ont été généré comme précurseur de carbène, et la réaction de transfert de carbène a été effectuée en présence de Rh2(OAc)4. Les résultats montrent une compétition entre la réaction de Buchner et l’insertion C‒H en position benzylique, dépendant de la substituant du diazo. Des calculs de DFT ont ensuite été réalisés pour compléter les informations obtenues expérimentalement. Le deuxième axe majeur de ce manuscrit a consisté à recherche une alternative aux composés diazo pour effectuer des additions de carbènes asymétriques sur des composés aromatiques. Des précurseurs de type N-sulfonyle-1,2,3-triazole ont été synthétisé en utilisant la méthode de CuAAC. La réaction intermoléculaire de cycloaddition [3+2] formelle avec des aromatique catalysés par des complexes Rh(II) chiraux a ensuite été étudié
The work presented in this manuscript is divided into two main parts. Firstly, a study about the problem of chemoselectivity during the intramolecular carbene transfer reaction will be presented. The diazo compound bearing different substituent was synthesized as precursor of carbene, and then the carbene transfer reaction was performed in the presence of the Rh2(OAc)4 catalyst. The result displayed the competition between Buchner reaction and C‒H insertion reaction at benzylic position, depended on the substituent. DFT calculations were subsequently conducted to complete the information obtained experimentally. The second major focus of this manuscript involves exploring the reactivity of N-sulfonyl-1,2,3-triazole. N-sulfonyl-1,2,3-triazole precursors were generated using the CuAAC method. The intermolecular formal [3+2] cycloaddition reaction with aromatics catalysed by chiral Rh(II) was then studied
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Trupina, Snjezana. « Synthesis of Metalloporphyrins with Oligothiophenes as Probes for Amyloid Diseases ». Thesis, Linköping University, Linköping University, Organic Chemistry, 2010. http://urn.kb.se/resolve?urn=urn:nbn:se:liu:diva-57989.

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Abnormal aggregation of misfolded proteins is related to numerous neurodegenerative diseases, which include Alzheimer’s, Parkinson’s disease and prion diseases. Luminescent conjugated probes (LCPs) have been used as dyes for these supramolecular assemblies termed amyloid fibrils. To these probes, metalloporphyrin (MP) derivates have been attached to achieve new spectroscopic properties, which will allow for new ways to study protein aggregation diseases.

In this thesis the synthesis of two different LCPs anchored porphyrin derivates are described. The LCPs are synthesized from 3-thiopheneacetic acid and additional thiophene units are added with the use of Suzuki cross coupling reaction. The porphyrin is synthesized from pyrrol, benzaldehyde and methyl-4- formylbenzoate in a condensation reaction. In the first target molecule (TM) the porphyrin and thiophene are coupled with a spacer and the second one is a direct coupling between the two compounds.

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Tilliet, Mélanie. « Synthesis and study of new oxazoline-based ligands ». Doctoral thesis, KTH, Organisk kemi, 2008. http://urn.kb.se/resolve?urn=urn:nbn:se:kth:diva-4858.

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This thesis deals with the study of oxazoline-based ligands in metal-catalyzed asymmetric reactions. The first part describes the synthesis of six new bifunctinal pyridine-bis(oxazoline) ligands and their applications in asymmetric metal-catalysis. These ligands, in addition to a Lewis acid coordination site, are equipped with a Lewis basic part in the 4-position of the oxazoline rings. Dual activation by means of this system was probed in cyanide addition to aldehydes. The second part is concerned with the synthesis of two pyridine-bis(oxazoline) ligands bearing bulky triazole groups in the 4-position of the oxazoline rings and a macrocyclic ligand consisting of a pyridine-bis(oxazoline) moiety and a diaza-18-crown-6 ether. The synthesis of these compounds benefits from the use of “click chemistry”. The ligands thus obtained were tested in different asymmetric catalytic reactions. Complexation studies with different bifunctional molecules that could bind into the cavity of the macrocycle were carried out using NMR spectroscopy. A third chapter is devoted to the synthesis of a supported pyridine-bis(oxazoline) catalyst and its use in catalysis. The pyridine-bis(oxazoline) ligand was efficiently connected to a polystyrene resin via a robust triazole linker. This resin could be employed in different metal-catalyzed asymmetric reactions and good results were obtained in terms of yield and enantioselectivity. Moreover, this polymer-bound ligand could be easily and efficiently recycled. Finally, the last part deals with the use of a hydroxy-containing phosphinooxazoline ligand in the hydrosilylation of imines and in the asymmetric intermolecular Heck reaction. A cationic iridium complex of this ligand was studied by NMR spectroscopy.
QC 20100914
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Winberg, Karl Johan. « Carborane Derivatives for Nuclide Therapy and Imaging : Synthesis and Radio-labelling ». Doctoral thesis, Uppsala : Acta Universitatis Upsaliensis : Univ-bibl. [distributör], 2003. http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-3561.

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Fyrner, Timmy. « Synthesis of Structures Related to Antifreeze Glycoproteins ». Thesis, Linköping University, The Department of Physics, Chemistry and Biology, 2005. http://urn.kb.se/resolve?urn=urn:nbn:se:liu:diva-11941.

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In this thesis, synthesis of structures related to antifreeze glycoproteins (AFGPs) are presented. Synthetic routes to a protected carbohydrate derivative, 2,3,4,6-tetra-O-benzyl-β-galactopyranosyl-(1→3)-2-deoxy-2-azido-4,6-di-O-benzyl-β-D-thio-1-galactopyranoside, and a tBu-Ala-Thr-Ala-Fmoc tripeptide, are described. These compounds are meant to be used in the assembly of AFGPs and analogues thereof. A Gal-GlcN disaccharide was synthesized via glycosylation between the donor, bromo-2-O-benzoyl-3,4,6-tri-O-benzyl-α-Dgalactopyranoside, and acceptor, ethyl 4,6-O-benzylidene-2-deoxy-2-N-phthalimido-β-D-1-thio-glucopyranoside, using silver triflate activation. Subsequent epimerization to a Gal-GalN disaccharide was achieved using Moffatt oxidation followed by L-selectride® reduction. The tripeptide was synthesized in a short and convenient manner using solid phase peptide synthesis with immobilized Fmoc-Ala on Wang® resins as starting point.

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Larsson, Andreas. « Synthesis, structure and conformation of oligo- and polysaccharides ». Doctoral thesis, Stockholm University, Department of Organic Chemistry, 2004. http://urn.kb.se/resolve?urn=urn:nbn:se:su:diva-172.

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Carbohydrates are a complex group of biomolecules with a high structural diversity. Their almost omnipresent occurrence has generated a broad field of research in both biology and chemistry. This thesis focuses on three different aspects of carbohydrate chemistry, synthesis, structure elucidation and the conformational analysis of carbohydrates.

The first paper describes the synthesis of a penta- and a tetrasaccharide related to the highly branched capsular polysaccharide from Streptococcus pneumoniae type 37. In the second paper, the structure of the O-antigenic repeating unit from the lipopolysaccharide of E. coli 396/C1 was determined along with indications of the structure of the biological repeating unit. In addition, its structural and immunological relationship with E. coli O126 is discussed. In the third paper, partially protected galactopyranosides were examined to clarify the origin of an intriguing 4JHO,H coupling, where a W-mediated coupling pathway was found to operate. In the fourth paper, the conformation of methyl a-cellobioside is studied with a combination of molecular dynamics simulations and NMR spectroscopy. In addition to the expected syn-conformation, detection and quantification of anti-ø and anti-ψ conformers was also possible.

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Esfandiarfard, Keyhan. « Novel Organophosphorus Compounds for Materials and Organic Synthesis ». Doctoral thesis, Uppsala universitet, Molekylär biomimetik, 2017. http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-328295.

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This thesis is devoted to the development of new organophosphorus compounds for potential uses in material science and as reagents in Organic Chemistry. Organophosphorus compounds in a single molecule or organic electronics context are appealing as the phosphorous centers perturb the electronic properties of the π-conjugated systems while at the same time provide synthetic handles for subsequent synthetic modifications. As such, new synthetic methodology to such compounds and the exploration of new building blocks is of considerable interest. In a different study, novel organophosphorus compounds are synthesized and shown to promote a reaction in Organic Chemistry that has previously not been possible, i.e. the stereoselective reductive coupling of aldehydes to alkenes. Such developments enlarge the toolkit of reactions that are available to Organic Chemists, and may impact the synthetic routes to pharmaceuticals and other important commodity chemicals. A general introduction of the key structural unit of this thesis, phosphaalkenes, is given in the first chapter. The synthesis, reactivity, properties and applications of these P=C double bond containing compounds are highlighted. The Wittig reaction and its variations as well as the phosphorus analogues that produce phosphaalkenes are outlined in detail. The second chapter is dedicated to the synthesis of a precursor that is used for the preparation of novel π-conjugated, organophosphorus compounds. C,C-Dibromophosphaalkenes are prepared and the halide substituents are used for the selective introduction of acetylene units. Besides the phosphaalkenes, the successful syntheses of two new diphosphenes is presented, indicating a broad applicability of the precursors. The third chapter is dedicated to the isolation of a metal-free phosphanylphosphonate that transforms aldehydes quantitatively to their corresponding E-phosphaalkenes in a transition metal-free phospha-HWE (Horner-Wadsworth-Emmons) reaction. The reaction benefits from mild conditions, high E-stereoselectivity, and a broad substrate scope. In the last chapter, a novel method for the reductive coupling of aldehydes to olefins is introduced. The reaction, which is a vast improvement over the McMurry coupling, allows for the selective synthesis of symmetrical and most importantly unsymmetrical E-alkenes. The phosphanylphosphonate mentioned above is the reagent that facilitates the coupling of the aldehydes via a phosphaalkene intermediate. This one-pot reaction benefits from mild conditions, good conversions, and high E-stereoselectivity. In summary, the thesis presents novel aspects of organophosphorus chemistry. These include the preparations and exploration of interesting precursors for the construction of π-conjugated organophosphorus compounds, and the use of organophosphorus reagents for unprecedented transformations in Organic Chemistry.
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BERTON, GIACOMO. « SYNTHESIS OF TRIPHENYLENES FOR SUPRAMOLECULAR APPLICATIONS ». Doctoral thesis, Università degli Studi di Trieste, 2020. http://hdl.handle.net/11368/2969361.

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In this Doctoral Thesis, through several examples of new chemical modifications characterized by high yields and selectivities and new supramolecular structures, held together by a wide range of intermolecular forces forming several new host systems, we reached our target to revamp triphenylene and derivatives as a new molecular scaffold in supramolecular chemistry. More specifically, the introduction in our triphenylenic scaffold of alkyl thiol chains allowed the formation of sulphide and disulphide covalent cages, while by insertion of pyridine moieties through Mannich reaction it was possible to obtain transition metal coordination cages upon addition of metal corners. The creation of a tris-acid from the original scaffold allowed the investigation of self-aggregation capsules through hydrogen bonds between carboxylic acids, and the functionalization with charged polytails attached to the central triphenylenic core, alternated with apolar substituents, allowed solubilization in water with the formation of very small micelles. Moreover, the interaction between positively charged and negatively charged triphenylenes permitted the creation of peculiar ionic hetero-dimeric capsules. We are sure that this will spur future investigation on the capsules and cages presented in this work, enriching the scientific community involved in this interdisciplinary field of research.
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Hagberg, Daniel. « Synthesis of Organic Chromophores for Dye Sensitized Solar Cells ». Licentiate thesis, Stockholm : Kemi, Kungliga Tekniska högskolan, 2007. http://urn.kb.se/resolve?urn=urn:nbn:se:kth:diva-4600.

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Livres sur le sujet "Organic Synthessis"

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Carruthers, W. Some modern methods of organic synthesis. 3e éd. Cambridge [Cambridgeshire] : Cambridge University Press, 1986.

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1944-, Mulzer J., et Waldmann H, dir. Organic synthesis highlights. Weinheim : VCH, 1991.

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Hans-Günther, Schmalz, et Wirth Thomas 1964-, dir. Organic synthesis highlights V. Weinheim : Wiley-VCH, 2003.

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Smith, Michael. Organic synthesis. New York : McGraw-Hill, 1994.

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Taber, Douglass F. Organic Synthesis. Hoboken, NJ, USA : John Wiley & Sons, Inc., 2006. http://dx.doi.org/10.1002/0470056312.

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Michael, Smith. Organic synthesis. 2e éd. Boston : McGraw-Hill, 2002.

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Smith, Michael B. Organic synthesis. New York : McGraw-Hill, 1994.

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Willis, Christine L. Organic synthesis. Oxford : Oxford University Press, 1995.

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Volke, J. Electrochemistry in organic synthesis. Berlin : Springer-Verlag, 1994.

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Smit, W. A. Organic synthesis : The science behind the art. Cambridge, UK : Royal Society of Chemistry, 1998.

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Chapitres de livres sur le sujet "Organic Synthessis"

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Yamada, Shinji. « Organic Synthesis ». Dans The Cation–π Interaction, 95–143. Singapore : Springer Nature Singapore, 2022. http://dx.doi.org/10.1007/978-981-19-7335-2_4.

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Ameta, Chetna, Arpit Kumar Pathak et P. B. Punjabi. « Organic Synthesis ». Dans Sonochemistry, 45–113. Toronto : Apple Academic Press, 2018. : Apple Academic Press, 2018. http://dx.doi.org/10.1201/b22323-4.

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Okuyama, Tadashi, et Howard Maskill. « Organic Synthesis ». Dans Organic Chemistry. Oxford University Press, 2013. http://dx.doi.org/10.1093/hesc/9780199693276.003.0023.

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This chapter looks at the reactions used in organic synthesis. It defines organic synthesis as the directed preparation of a sought compound usually, but not invariably, with some structural complexity from simple, readily available compounds. The chapter also develops the concept of retrosynthesis further and examines how to identify routes for syntheses of target compounds by applying organic reactions. Organic synthesis is one of the ultimate goals of organic chemistry and provides limitless opportunities to challenge the scientific imagination. The chapter then proceeds to discuss the synthons and the corresponding reagents as well as the reaction selectivity. Finally, the chapter elaborates on linear and convergent strategies, and presents some examples of organic synthesis.
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Willis, Christine L., et Martin Wills. « Selected organic syntheses ». Dans Organic Synthesis. Oxford University Press, 2022. http://dx.doi.org/10.1093/hesc/9780198557913.003.0008.

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This chapter presents a case history of selected syntheses of a class of natural products known as the pyrrolizidine alkaloids to bring together the aspects of organic synthesis. The pyrrolizidines are a group of alkaloids which are characterized by the presence of the basic necine skeleton. The pyrrolizidine alkaloids exhibit remarkably diverse types of biological activity and have been reported to act as antitumor agents. The chapter then describes four methods for the synthesis of the pyrrolizidine alkaloids. Each route has its own particular merits, e.g. the route to platynecine gives the highest yield, the second method for the synthesis of retronecine uses stereoselectivity to good effect, and of course, the route to (+)–heliotridine is the only enantioselective synthesis.
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Morrow, Gary W. « Brief Organic Review ». Dans Bioorganic Synthesis. Oxford University Press, 2016. http://dx.doi.org/10.1093/oso/9780199860531.003.0004.

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In addition to simple hydrocarbon structures (alkanes, alkenes, alkynes, and aromatic systems) and alkyl groups (methyl, ethyl, propyl, isopropyl, etc.), this text assumes a familiarity with the most common functional groups associated with organic chemical structures and their basic reactivity patterns. Table 1.1 summarizes the names and structures of some of the more important functional groups we will be dealing with throughout the remainder of the book. It is important to remember that functional groups containing O or N with nonbonding electrons have an affinity for both protic and Lewis acids and are important participators in H-bonding. Groups containing a carbonyl (C=O) function are especially important, as these bonds are strongly polarized (δ+C=Oδ–), the C atom being electron deficient and the O atom electron excessive; this strong polarization is mainly responsible for the familiar reactivity patterns associated with carbonyl compounds. Figure 1.1 depicts the standard classification of isomers in organic chemical structures. Recall that constitutional isomers are compounds with the same molecular formula but different atom connectivity, such as 1-butanol versus 2-butanol. Stereoisomers, on the other hand, are compounds with the same formula and the same atom connectivity, differing from one another only in the three-dimensional orientation of their atoms in space. These are divided into two groups: enantiomers and diastereomers. Enantiomers are nonsuperimposable mirror image molecules whose asymmetry is usually the result of a tetrahedral carbon atom with four different atoms or groups attached to it, as in the 2-butanol enantiomers. Such chiral molecules rotate the plane of polarized light either (+) or (−) and so are said to be optically active. Achiral molecules, such as 1-butanol, do not rotate the plane of polarized light and so are optically inactive. A standard formalism for representation of a chiral center is to use bond line drawings with two of the four atoms or groups lying in the plane of the paper, a third projecting outward (wedge bond), and the fourth projecting inward (dashed bond).
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« Alkyne Metathesis in Synthesis : Syntheses of (+)-Ferrugine and Anatoxin-α ». Dans Organic Synthesis, 82–83. Hoboken, NJ, USA : John Wiley & Sons, Inc., 2006. http://dx.doi.org/10.1002/0470056312.ch42.

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Smith, Michael B. « Retrosynthesis, Stereochemistry, and Conformations ». Dans Organic Synthesis, 1–60. Elsevier, 2017. http://dx.doi.org/10.1016/b978-0-12-800720-4.00001-5.

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Smith, Michael B. « Acids, Bases, and Addition Reactions ». Dans Organic Synthesis, 61–95. Elsevier, 2017. http://dx.doi.org/10.1016/b978-0-12-800720-4.00002-7.

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Smith, Michael B. « Functional Group Exchange Reactions ». Dans Organic Synthesis, 97–160. Elsevier, 2017. http://dx.doi.org/10.1016/b978-0-12-800720-4.00003-9.

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Smith, Michael B. « Acids, Bases, and Functional Group Exchange Reactions ». Dans Organic Synthesis, 161–83. Elsevier, 2017. http://dx.doi.org/10.1016/b978-0-12-800720-4.00004-0.

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Actes de conférences sur le sujet "Organic Synthessis"

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Smith, Warren E., William J. Dallas, Heidi A. Schlitt et Walter Kullmann. « Reconstructing a Vector Current Distribution from its Magnetic Field Using Linear Estimation Theory ». Dans Signal Recovery and Synthesis. Washington, D.C. : Optica Publishing Group, 1986. http://dx.doi.org/10.1364/srs.1986.wa2.

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Several methods currently exist for exploring the three-dimensional structure of the organs of the human body. They include x-ray computed tomography (CT),1 magnetic resonance imaging (MRI),2 and emission computed tomography (ECT).3,4 These techniques provide spatial information about an organ's attenuation coefficient, proton density, or the ability of the organ to take up a radioactive pharmaceutical, respectively.
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Barbosa, Alexandre F., et Arlene G. Corrêa. « Synthesis of 9-substituted 9-deazaguanine derivatives ». Dans 14th Brazilian Meeting on Organic Synthesis. São Paulo : Editora Edgard Blücher, 2013. http://dx.doi.org/10.5151/chempro-14bmos-r0125-2.

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Araujo, Yara J. K., Isac G. Rosset et André L. M. Porto. « A New Synthesis of Benzonitriles Catalyzed by Microwave Irradiation ». Dans 14th Brazilian Meeting on Organic Synthesis. São Paulo : Editora Edgard Blücher, 2013. http://dx.doi.org/10.5151/chempro-14bmos-r0003-1.

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Rosset, Isac G., et André L. M. Porto. « Transesterification and Quantification by 1H NMR of Triester Oleate by Candida antarctica Lipase ». Dans 14th Brazilian Meeting on Organic Synthesis. São Paulo : Editora Edgard Blücher, 2013. http://dx.doi.org/10.5151/chempro-14bmos-r0004-1.

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da Silva, A. J. M., C. Schneider et V. Snieckus. « Construction of Polyarylated Fluorenones via chemoselective Ru- and Pd-Catalyzed Suzuki Cross-Coupling Reactions ». Dans 14th Brazilian Meeting on Organic Synthesis. São Paulo : Editora Edgard Blücher, 2013. http://dx.doi.org/10.5151/chempro-14bmos-r0007-1.

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Andrighetto, Rosália, Helio G. Bonacorso, Jussara Navarini, Nícolas Krüger, Marcos A. P. Martins et Nilo Zanatta. « Highly Efficient Synthesis of CF3-Containing 7-Aminoquinolines From Cyclocondensation Reaction of Trifluoroacetyl Enamine Precursors ». Dans 14th Brazilian Meeting on Organic Synthesis. São Paulo : Editora Edgard Blücher, 2013. http://dx.doi.org/10.5151/chempro-14bmos-r0008-1.

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Andrighetto, Rosália, Helio G. Bonacorso, Jussara Navarini, Nícolas Krüger, Marcos A. P. Martins et Nilo Zanatta. « General Pathway for One-Pot Synthesis of Trifluoromethyl- Containing 2-Amino-cycloalka[b][1,8]naphthyridines ». Dans 14th Brazilian Meeting on Organic Synthesis. São Paulo : Editora Edgard Blücher, 2013. http://dx.doi.org/10.5151/chempro-14bmos-r0008-2.

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Navarini, Jussara, Helio G. Bonacorso, Carson W. Wiethan, Rosália Andrighetto, Fábio M. Luz, Marcos A. P. Martins et Nilo Zanatta. « Synthesis of New 5-Trifluoromethyl-3-alkyl[aryl(heteroaryl)]-4- (2-benzyl-3-hydroxycyclohex-2-enone-2-yl)-1H-pyrazoles by a Ring-Opening Reaction ». Dans 14th Brazilian Meeting on Organic Synthesis. São Paulo : Editora Edgard Blücher, 2013. http://dx.doi.org/10.5151/chempro-14bmos-r0009-1.

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Navarini, Jussara, Helio G. Bonacorso, Carson W. Wiethan, Rosália Andrighetto, Marcos A. P. Martins et Nilo Zanatta. « Molecular Iodine - An Efficient Oxidative Reagent for Aromatization of Trifluoromethyl Substituted Chromenones ». Dans 14th Brazilian Meeting on Organic Synthesis. São Paulo : Editora Edgard Blücher, 2013. http://dx.doi.org/10.5151/chempro-14bmos-r0009-2.

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Rampon, Daniel S., Aloir A. Merlo et Paulo H. Schneider. « Synthesis of New Liquid-Crystalline Selenophenes via Electrophilic Cyclization of (Z)-Selenoenynes ». Dans 14th Brazilian Meeting on Organic Synthesis. São Paulo : Editora Edgard Blücher, 2013. http://dx.doi.org/10.5151/chempro-14bmos-r0011-1.

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Rapports d'organisations sur le sujet "Organic Synthessis"

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Reilly, S. D., D. R. Click, S. K. Grumbine, B. L. Scott et J. G. Watkins. Asymmetric catalysis in organic synthesis. Office of Scientific and Technical Information (OSTI), novembre 1998. http://dx.doi.org/10.2172/677032.

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Rittman, Bruce. Biotic Transformations of Organic Contaminants. The Groundwater Project, 2023. http://dx.doi.org/10.21083/ousn4116.

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Biodegradation—the breakdown of organic matter by microorganisms—is an important groundwater process that occurs naturally and is especially important for the in situ cleanup of contaminated groundwater. Pollutant biodegradation follows well-established principles that are summarized in this book. The first principle is that the microorganisms must grow and sustain themselves by oxidizing an electron-donor substrate (food) and transferring the electrons to an electron-acceptor substrate (respiration). This electron flow generates energy that the microorganisms use to fuel biomass synthesis. Most pollutants are either an electron acceptor or an electron donor, which means that their biotransformation can grow and sustain the microorganisms. Accordingly, it is critical to understand whether a pollutant is an electron donor or electron acceptor. This book systematically describes the biodegradation mechanisms for common organic pollutants in groundwater: The author identifies if the pollutant behaves as an electron donor or acceptor, and points out when special activation reactions are necessary to initiate biodegradation and put the pollutant into a chemical form that allows it to be an energy-yielding electron donor or acceptor. Special attention is given to organics derived from petroleum and those that have chlorine, fluorine, and nitro substituents.
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Liu, Zhijian. Novel Aryne Chemistry in Organic Synthesis. Office of Scientific and Technical Information (OSTI), décembre 2006. http://dx.doi.org/10.2172/897369.

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Bernstein, J., J. Y. Becker, S. Bittner et S. S. Shaik. Electrically Conducting Organic Materials : Design, Synthesis and Characterization. Fort Belvoir, VA : Defense Technical Information Center, février 1988. http://dx.doi.org/10.21236/ada195095.

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Folz, Katherine E. Synthesis and Characterization of Novel Organic Conducting Polymers. Fort Belvoir, VA : Defense Technical Information Center, mai 2004. http://dx.doi.org/10.21236/ada425003.

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Ramírez, David A., Cecilia Silva-Díaz, Johan Ninanya, Mariella Carbajal, Javier Rinza, Suresh K. Kakraliya, Marcel Gatto et Jan Kreuze. Potato zero-tillage and mulching is promising in achieving agronomic gain in Asia. INPLASY - International Platform of Registered Systematic Review and Meta-analysis Protocols, juin 2022. http://dx.doi.org/10.37766/inplasy2022.6.0072.

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Review question / Objective: The objective of this review is to analyze the effect of zero-tillage and organic mulching (with emphasis on rice-straw) on several Key Performance Indicators (KPIs) related to productivity, resources-use efficiency, and soil health, as well as, C footprint, and weed control for growing potatoes in rice-based systems in Asia. Can zero-tillage and organic mulching increase agronomic gain in potatoes crop in Asia? Rationale: Potato cultivation under zero-tillage and mulching (PZTM) between rice or rice-other crops projects a sustainable intensification of rice-based systems reducing mechanical soil disturbance with a concomitant increase of soil organic matter. However, collection, analysis, and synthesis of experiences in Asia, where this technology was mainly reported, is missing in the scientific literature. This effort, presented in this review, is crucial as a starting point for establishing if PTZM experiences have improved indicators related to productivity, resource use efficiency and soil health, and C footprint and weed management to achieve Agronomic Gain.
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Zhang, Honghu. Bioinspired synthesis and self-assembly of hybrid organic–inorganic nanomaterials. Office of Scientific and Technical Information (OSTI), décembre 2016. http://dx.doi.org/10.2172/1409201.

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Sun, Ning. Process scale-up and optimization of the metal-organic framework synthesis. Office of Scientific and Technical Information (OSTI), mai 2020. http://dx.doi.org/10.2172/1618846.

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Singh, Anjali. Amino Acids : Building Blocks of Proteins. ConductScience, juin 2022. http://dx.doi.org/10.55157/cs20220612.

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Amino acids are essential organic compounds serving as protein building blocks. Recognized for their biological roles, they underpin proteins' structure and interactions. Classified by polarity and nutritional necessity, essential amino acids, not synthesized by the body, include histidine, leucine, lysine, and more, while non-essential ones are produced internally. These molecules exhibit diverse functions, from neurotransmitter precursor synthesis to immune support. Industries leverage amino acids in animal feed, artificial sweeteners, flavor enhancers, and drug manufacturing, highlighting their vital role in various applications beyond biological systems.
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Matnishyan, Hakob A. Synthesis of New Organic Semiconducting Polymer Materials Having High Radiowave Absorption Rate. Fort Belvoir, VA : Defense Technical Information Center, novembre 2008. http://dx.doi.org/10.21236/ada494519.

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