Livres : « Modelli in vivo »

1

1974-, Stevenson Christopher S., Morgan Douglas W. 1951- et Marshall Lisa A. 1954-, dir. In vivo models of inflammation. 2^e éd. Basel : Birkhäuser, 2006.

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1951-, Morgan Douglas W., et Marshall Lisa A. 1954-, dir. In vivo models of inflammation. Basel : Birkhauser Verlag, 1999.

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Ntziachristos, Vasilis. Textbook of in vivo imaging in vertebrates. Chichester, West Sussex : J. Wiley, 2007.

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van, Boxtel Christoffel Jos, Holford N. H. G et Danhof M, dir. The In vivo study of drug action. Amsterdam : Elsevier, 1992.

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1953-, Raeburn D., et Giembycz M. A. 1961-, dir. Airways smooth muscle : Modelling the asthmatic response in vivo. Basel : Birkhäuser Verlag, 1996.

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International Symposium on Nephrotoxicity (3rd 1987 University of Surrey). Nephrotoxicity : In vitro to in vivo : animals to man. New York : Plenum Press, 1989.

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Ferrick, David A. Transgenic mice as a in vivo model for self reactivity. Austin : R.G. Landes Co., 1994.

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C, Sahu Saura, et Casciano Daniel, dir. Nanotoxicity : In vivo and in vitro models to health risks. Chichester, West Sussex : John Wiley & Sons, 2009.

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C, Sahu Saura, dir. Hepatotoxicity : From genomics to in vitro and in vivo models. Chichester, England : John Wiley & Sons, 2007.

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Museo del vino (Torgiano, Italy), dir. Bozzetti, modelli e grisailles dal XVI al XVIII secolo : Fondazione Lungarotti, Torgiano, Museo del Vino, 28 ottobre-20 novembre 1988. Milano : Electa, 1988.

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C, Sahu Saura, et Casciano Daniel, dir. Nanotoxicity : From in vivo and in vitro models to health risks. Chichester, West Sussex, UK : John Wiley, 2009.

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C, Sahu Saura, dir. Hepatotoxicity : From genomics to in vitro and in vivo models. Chichester, England : John Wiley & Sons, 2007.

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McGarry, Kathleen. Inter vivos transfers and intended bequests. Cambridge, MA : National Bureau of Economic Research, 1997.

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Calabrese, Edward J. Principles of animal extrapolation. Chelsea, Mich : Lewis Publishers, 1991.

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Altonji, Joseph G. Parental altruism and inter vivos transfers : Theory and evidence. Cambridge, MA : National Bureau of Economic Research, 1995.

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Coccia, Maurizio. Concerto italiano : Il modo in cui si vive nel nostro Paese è pazzesco eppure potrebbe diventare un modello per il mondo : provare per credere. Soveria Mannelli (Catanzaro) : Rubbettino, 1998.

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Poterba, James M. Estate and gift taxes and incentives for inter vivos giving in the United States. Cambridge, MA : National Bureau of Economic Research, 1998.

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Bowman, Ryan, Hannah Schwennesen, Kafui Dzirasa et Rainbo Hultman. In Vivo Circuit Analysis. Sous la direction de Dennis S. Charney, Eric J. Nestler, Pamela Sklar et Joseph D. Buxbaum. Oxford University Press, 2017. http://dx.doi.org/10.1093/med/9780190681425.003.0007.

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Breakthroughs in understanding neural circuit activity hold much promise for developing next generation therapeutics for psychiatric disorders. Determination of how dynamic activity is coordinated across brain regions to effect specific behavioral function (or dysfunction) enables the development of therapeutics with increased specificity and fewer side effects. This chapter discusses methodologies for measuring neural circuit activity in humans and in animal models, and describes a bidirectional research pipeline whereby studies in humans are followed by tightly controlled studies in animal models that can then be applied back to humans. Targeted neural circuit manipulations from these studies are already being applied to a wide range of therapeutic strategies.

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(Editor), Vasilis Ntziachristos, Anne Leroy-Willig (Editor) et Bertrand Tavitian (Editor), dir. Textbook of in vivo Imaging in Vertebrates. Wiley, 2007.

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Ntziachristos, Vasilis. Textbook of in Vivo Imaging in Vertebrates. Wiley & Sons, Incorporated, John, 2007.

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Ntziachristos, Vasilis, Bertrand Tavitian et Anne Leroy-Willig. Textbook of in Vivo Imaging in Vertebrates. Wiley & Sons, Limited, John, 2007.

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Ntziachristos, Vasilis, Bertrand Tavitian et Anne Leroy-Willig. Textbook of in Vivo Imaging in Vertebrates. Wiley & Sons, Incorporated, John, 2007.

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23

Arnold, W. David, et Arthur H. M. Burghes. In Vitro and In Vivo Models of Spinal Muscular Atrophy. Oxford University Press, 2017. http://dx.doi.org/10.1093/med/9780199937837.003.0035.

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Spinal muscular Atrophy (SMA) is caused by reduced levels of the SMN protein. In humans this is caused by loss of SMN1 and retention of SMN2. The challenge in modelling SMA, in either tissue culture cells or animals, is first to obtain the desired SMN levels equivalent to what is observed in SMA. Various models of SMA in tissue culture cells, invertebrates, and mammals have been created have been developed. The targets of SMN reduction that are most relevant for the pathogenesis of SMA and how the phenotype of SMA can be modified independent of SMN levels are two important questions that remain unanswered. Here the current in vitro and in vivo models of SMA are summarized.

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(Editor), Douglas W. Morgan, et Lisa A. Marshall (Editor), dir. In Vivo Models of Inflammation (Pir (Series).). Birkhauser, 1999.

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25

bellezza, Lo studio di. Taccuino Di Bellezza : 60 Modelli Di Viso Di Modello Femminile per Trucco e Acconciature, con 60 Pagine Vuote per Prendere Appunti, Disegnare o Scrivere il Registro Del Prodotto. Independently Published, 2021.

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(Editor), Lisa A. Marshall, et Douglas W. Morgan (Editor), dir. In Vivo Models of Inflammation (Progress in Inflammation Research). Birkhauser, 2006.

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(Editor), Christopher S. Stevenson, Lisa A. Marshall (Editor) et Douglas W. Morgan (Editor), dir. In Vivo Models of Inflammation : Volume 1 (Progress in Inflammation Research). 2^e éd. Birkhäuser Basel, 2006.

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(Editor), Christopher S. Stevenson, Lisa A. Marshall (Editor) et Douglas W. Morgan (Editor), dir. In Vivo Models of Inflammation : Volume 2 (Progress in Inflammation Research). 2^e éd. Birkhäuser Basel, 2006.

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29

Specter, Steven, Herman Friedman et Mauro Bendinelli. In Vivo Models of HIV Disease and Control. Springer, 2007.

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Bach, Peter. Nephrotoxicity:In Vitro and in Vivo, Animals to Man. Springer, 1989.

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31

Casciano, Daniel A., et Saura C. Sahu. Nanotoxicity : From in Vivo and in Vitro Models to Health Risks. Wiley & Sons, Limited, John, 2009.

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32

Casciano, Daniel A., et Saura C. Sahu. Nanotoxicity : From in Vivo and in Vitro Models to Health Risks. Wiley & Sons, Incorporated, John, 2009.

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33

(Editor), Herman Friedman, Steven Specter (Editor) et Mauro Bendinelli (Editor), dir. In vivo Models of HIV Disease and Control (Infectious Agents and Pathogenesis). Springer, 2005.

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34

(Editor), David Raeburn, et M. A. Giembycz (Editor), dir. Airways Smooth Muscle : Modelling the Asthmatic Response in Vivo (Respiratory Pharmacology and Pharmacotherapy). Birkhauser, 1996.

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35

(Editor), David Raeburn, et Mark A. Giembycz (Editor), dir. Airways Smooth Muscle : Modelling the Asthmatic Response In Vivo (Respiratory Pharmacology and Pharmacotherapy). Birkhauser, 1996.

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36

François-Marie Banier : Vive la Vie. Steidl Photography International, 2009.

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Hepatotoxicity : From Genomics to In Vitro and In Vivo Models. Wiley, 2008.

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38

bellezza, Lo studio di. Truccatore Faccia Della Sposa il Mio Libro Di Trucco : 60 Modelli Di Viso per Modelli Da Sposa per Trucco e Acconciature, con 60 Pagine Vuote per Prendere Appunti, Disegnare o Scrivere il Registro Del Prodotto. Independently Published, 2021.

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39

von Caemmerer, S. Biochemical Models of Leaf Photosynthesis. CSIRO Publishing, 2000. http://dx.doi.org/10.1071/9780643103405.

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Increasing concerns of global climate change have stimulated research interests in all aspects of carbon exchange. This has restored interest in leaf photosynthetic models to predict and assess changes in photosynthetic CO2 assimilation in different environments. This is a comprehensive presentation of the most widely used models of steady-state photosynthesis by an author who is a world authority. Treatments of CO3, CO4 and intermediate pathways of photosynthesis in relation to environment have been update to include work on antisense transgenic plants. It will be a standard reference for the formal analysis of photosynthetic metabolism in vivo by advanced students and researchers.

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Merl, Dan, Joseph Lucas, Joseph Nevins, Haige Shen et Mike West. Trans-study projection of genomic biomarkers in analysis of oncogene deregulation and breast cancer. Sous la direction de Anthony O'Hagan et Mike West. Oxford University Press, 2018. http://dx.doi.org/10.1093/oxfordhb/9780198703174.013.6.

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This article focuses on the use of Bayesian concepts and methods in the trans-study projection of genomic biomarkers for the analysis of oncogene deregulation in breast cancer. The objective of the study is to determine the extent to which patterns of gene expression associated with experimentally induced oncogene pathway deregulation can be used to investigate oncogene pathway activity in real human cancers. This is often referred to as the in vitro to in vivo translation problem, which is addressed using Bayesian sparse factor regression analysis for model-based translation and refinement of in vitro generated signatures of oncogene pathway activity into the domain of human breast tumour tissue samples. The article first provides an overview of the role of oncogene pathway deregulation in human cancers before discussing the details of modelling and data analysis. It then considers the findings based on biological evaluation and Bayesian pathway annotation analysis.

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Burns, Tom, et Mike Firn. Model variance and model fidelity : The lessons from ACT. Sous la direction de Tom Burns et Mike Firn. Oxford University Press, 2017. http://dx.doi.org/10.1093/med/9780198754237.003.0004.

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This chapter takes the assertive community treatment (ACT) model of community outreach as a starting point and examines what can and what cannot be varied and still achieve good results. ACT has a special place in community outreach as it was the first model of care confirmed by research, and controversy has raged about the need, or otherwise, for ‘model fidelity’. The chapter identifies the core ingredients—small caseloads, in vivo psychosocial treatments, mainstreaming, flexibility, 24/7 availability—and examines the evidence for and against them. It pays particular attention to the roles of support workers and the medical member of the team. Later developments such as flexible assertive outreach (FACT) are also described.

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Crea I Tuoi Fumetti Personalizzati : Libro con 120+ Modelli in Bianco Pre-Formattati Senza Nuvolette per Disegnare Fumetti per Adulti, Ragazzi e Bambini. Viva la Creatività ! Independently Published, 2021.

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43

La Canna, Giovanni. Heart valve disease (mitral valve disease) : anatomy and morphology of the mitral valve. Oxford University Press, 2016. http://dx.doi.org/10.1093/med/9780198726012.003.0034.

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The mitral valve is a complex anatomical structure that includes the valve tissue (leaflets), the left atrioventricular junction (annulus), and the valve suspension system (chordae tendineae, papillary muscles, and left ventricle). Its functional anatomy can be analysed using two- and three-dimensional transthoracic and transoesophageal echocardiography. Based on certain hallmarks (commissures, clefts), in vivo mitral valve tissue anatomy can be accurately categorized. In addition, three-dimensional reconstruction provides a quantitative model for comprehensive valve analysis. This chapter describes the anatomy and morphology of the mitral valve, including the subvalvular suspension system and functional anatomy and dynamics of the mitral annulus.

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Wang, Sigen, Otto Zhou et Sha Chang. Carbon-nanotube field emission electron and X-ray technology for medical research and clinical applications. Sous la direction de A. V. Narlikar et Y. Y. Fu. Oxford University Press, 2017. http://dx.doi.org/10.1093/oxfordhb/9780199533060.013.19.

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This article describes carbon-nanotube based X-ray technologies for medical research and clinical applications, including an X-ray source, microfocus X-ray tube, microcomputed tomography scanner, stationary digital breast tomosynthesis, microradiotherapy system, and single-cell irradiation system. It first examines electron field emission from carbon nanotubes before discussing carbon-nanotube field emission electron and X-ray technologies in greater detail. It highlights the enormous promise of these systems in commercial and research application for the future in diagnostic medical imaging; in-vivo imaging of small-animal modelsfor pre-clinical cancer studies; security screening; industrial inspection; cancer radiotherapy of small-animal models for pre-clinical cancer studies; and basic cancer research using single-cell irradiation.

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Erdem, Uğur Murat, Nicholas Roy, John J. Leonard et Michael E. Hasselmo. Spatial and episodic memory. Oxford University Press, 2018. http://dx.doi.org/10.1093/oso/9780199674923.003.0029.

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The neuroscience of spatial memory is one of the most promising areas for developing biomimetic solutions to complex engineering challenges. Grid cells are neurons recorded in the medial entorhinal cortex that fire when rats are in an array of locations in the environment falling on the vertices of tightly packed equilateral triangles. Grid cells suggest an exciting new approach for enhancing robot simultaneous localization and mapping (SLAM) in changing environments and could provide a common map for situational awareness between human and robotic teammates. Current models of grid cells are well suited to robotics, as they utilize input from self-motion and sensory flow similar to inertial sensors and visual odometry in robots. Computational models, supported by in vivo neural activity data, demonstrate how grid cell representations could provide a substrate for goal-directed behavior using hierarchical forward planning that finds novel shortcut trajectories in changing environments.

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(Editor), X. Y. Xu, et M. W. Collins (Editor), dir. Haemodynamics of Arterial Organs : Comparison of Computational Predictions with In Vitro and In Vivo Data (Advances in Computational Bioengineering Vol 1). WIT Press (UK), 1999.

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Drug Distribution in the Body : In Vitro Prediction and Physiological Interpretation/the Cat As an in Vivo Model for Myocardial Ischemia and Infarction ... in Pharmacology and Clinical Pharmacology). Vch Pub, 1989.

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SaintJean, LeShana, et H. S. Baldwin. Origin and diversity of embryonic endothelium/endocardium. Sous la direction de José Maria Pérez-Pomares, Robert G. Kelly, Maurice van den Hoff, José Luis de la Pompa, David Sedmera, Cristina Basso et Deborah Henderson. Oxford University Press, 2018. http://dx.doi.org/10.1093/med/9780198757269.003.0005.

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The endocardium represents a distinct population of endothelial cells that arises during the initiation of heart development. Endocardial cells can easily be distinguished from most of the other cardiac cell types. However, endocardial and vascular endothelial cells contain a similar genetic profile that limits the ability to study each group independently. Despite these limitations, tremendous progress has been made in identifying the different roles of endocardial cells throughout heart development. Initial studies focused on the origin of endocardial cells and their role in valvulogenesis, trabeculation, and formation of the ventricular and atrial septum. With the advancement of microscopy and the availability of endocardial specific reporter models (in vitro and in vivo) we have obtained more insight into the molecular, structural, and functional complexity of the endocardium. Additional studies have demonstrated how the endocardium is also involved in the development of coronary vessels within the compact myocardium and in heart regeneration.

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Walker, Matthew C., et Robin S. B. Williams. Identifying the Molecular Mechanism of the Medium Chain Triglyceride (Ketogenic) Diet. Sous la direction de Dominic P. D’Agostino. Oxford University Press, 2016. http://dx.doi.org/10.1093/med/9780190497996.003.0033.

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The medium chain triglyceride (MCT) ketogenic diet provides a highly effective and commonly used approach for treating drug-resistant epilepsy. It is associated with elevated levels of two MCT-derived fatty acids, decanoioc and octanoic acids. Researchers have identified a role for decanoic acid and a range of novel related chemicals in seizure control in multiple acute in vitro and in vivo models. A principal mechanism of decanoic acid is direct inhibition of AMPA receptors, key excitatory neurotransmitter receptors widely recognized as a target for seizure control. These data suggest a therapeutic mechanism of the MCT ketogenic diet through a direct fatty acid–dependent mechanism, independent of ketosis. This discovery will enable the development of an improved and, potentially, better-tolerated diet and the generation of a corresponding pharmaceutical approach. The diet should be termed the MCT diet, as the consequent ketosis may not be necessary for seizure control.

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Rosa, Laura Nuño de la. Capturing Processes. Oxford University Press, 2018. http://dx.doi.org/10.1093/oso/9780198779636.003.0013.

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While a processual view of biological entities might be said to be congenial to embryologists, the intractability and speed of developmental processes traditionally led to an epistemological abandon of processes in favour of the advantages of discretizing ontogenies in arrays of patterns. It is not until the turn of the twenty-first century that the digital embryos obtained from in vivo microscopy have started to replace developmental series as the reference representations of development. This chapter looks at how new microscopy, molecular, and computer technologies for reconstructing biological processes are contributing to a processual understanding of development. First it investigates how time-lapse imaging has brought with it a radical dynamization, not only of the images, but also of the theories of development themselves. Next it explores the role that imaging technologies have played in the return of organicism in developmental biology. Finally, it focuses on how quantitative imaging contributes to the explanatory modelling of developmental processes.

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