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Articles de revues sur le sujet « Mimic-effect »

Auteur : Grafiati

Publié le 9 mars 2023

Mis à jour le 31 juillet 2025

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1

Gottlieb, S. "Smoking may mimic effect of antidepressants." BMJ 323, no. 7315 (2001): 713. http://dx.doi.org/10.1136/bmj.323.7315.713.

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Tsai, Jessica Chia-Chin, Natalie Sebanz, and Günther Knoblich. "The GROOP effect: Groups mimic group actions." Cognition 118, no. 1 (2011): 135–40. http://dx.doi.org/10.1016/j.cognition.2010.10.007.

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Cao, Chunhua, Eun Sook Kim, Yi-Hsin Chen, John Ferron, and Stephen Stark. "Exploring the Test of Covariate Moderation Effects in Multilevel MIMIC Models." Educational and Psychological Measurement 79, no. 3 (2018): 512–44. http://dx.doi.org/10.1177/0013164418793490.

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In multilevel multiple-indicator multiple-cause (MIMIC) models, covariates can interact at the within level, at the between level, or across levels. This study examines the performance of multilevel MIMIC models in estimating and detecting the interaction effect of two covariates through a simulation and provides an empirical demonstration of modeling the interaction in multilevel MIMIC models. The design factors include the location of the interaction effect (i.e., between, within, or across levels), cluster number, cluster size, intraclass correlation (ICC) level, magnitude of the interactio

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Tran, Kim Ngan, and Jong-il Choi. "Mimic microgravity effect on muscle transcriptome under ionizing radiation." Life Sciences in Space Research 32 (February 2022): 96–104. http://dx.doi.org/10.1016/j.lssr.2021.12.002.

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Huang, Suning, Rongquan He, Minhua Rong, Yiwu Dang, and Gang Chen. "Synergistic Effect of MiR-146a Mimic and Cetuximab on Hepatocellular Carcinoma Cells." BioMed Research International 2014 (2014): 1–15. http://dx.doi.org/10.1155/2014/384121.

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Previously, we found that the expression of microRNA-146a (miR-146a) was downregulated in hepatocellular carcinoma (HCC) formalin-fixed paraffin-embedded (FFPE) tissues compared to the adjacent noncancerous hepatic tissues. In the current study, we have explored thein vitroeffect of miR-146a on the malignant phenotypes of HCC cells. MiR-146a mimic could suppress cell growth and increase cellular apoptosis in HCC cell lines HepG2, HepB3, and SNU449, as assessed by spectrophotometry, fluorimetry, and fluorescence microscopy, respectively. Furthermore, western blot showed that miR-146a mimic down

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Toker, Lilach, Yuly Bersudsky, Inbar Plaschkes, et al. "Inositol-Related Gene Knockouts Mimic Lithium’s Effect on Mitochondrial Function." Neuropsychopharmacology 39, no. 2 (2013): 319–28. http://dx.doi.org/10.1038/npp.2013.194.

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Muszyńska-Pytel, M., P. Mikołajczyk, M. A. Pszczółkowski, and B. Cymborowski. "Juvenilizing effect of ecdysone mimic RH 5849 inGalleria mellonella larvae." Experientia 48, no. 10 (1992): 1013–17. http://dx.doi.org/10.1007/bf01919156.

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Azanza, Maria J. "Steady magnetic fields mimic the effect of caffeine on neurons." Brain Research 489, no. 1 (1989): 195–98. http://dx.doi.org/10.1016/0006-8993(89)90025-5.

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Jamali, Jamshid, Seyyed Mohammad Taghi Ayatollahi, and Peyman Jafari. "The Effect of Small Sample Size on Measurement Equivalence of Psychometric Questionnaires in MIMIC Model: A Simulation Study." BioMed Research International 2017 (2017): 1–12. http://dx.doi.org/10.1155/2017/7596101.

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Evaluating measurement equivalence (also known as differential item functioning (DIF)) is an important part of the process of validating psychometric questionnaires. This study aimed at evaluating the multiple indicators multiple causes (MIMIC) model for DIF detection when latent construct distribution is nonnormal and the focal group sample size is small. In this simulation-based study, Type I error rates and power of MIMIC model for detecting uniform-DIF were investigated under different combinations of reference to focal group sample size ratio, magnitude of the uniform-DIF effect, scale le

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Lin, Lin, and Yong Wang. "miR-548b-3p Regulates Proliferation, Apoptosis, and Mitochondrial Function by Targeting CIP2A in Hepatocellular Carcinoma." BioMed Research International 2018 (December 23, 2018): 1–9. http://dx.doi.org/10.1155/2018/7385426.

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The roles of miR-548b-3p in the progression of hepatocellular carcinoma (HCC) remain undiscovered. This study aims to explore the roles and mechanisms of miR-548b-3p in HCC. Using TCGA database, we found that miR-548b-3p expression was lower in HCC compared to the normal tissues, which was further confirmed by RT-qPCR of 20 cases of surgically resected HCC and corresponding normal tissues. miR-548b-3p mimic and inhibitor were transfected into Huh7 and SK-Hep-1 cells, respectively. MTT, colony formation, and cell cycle assays showed that miR-548b-3p mimic suppressed cell growth and G1/S cell cy

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Lapkina, E. Z., N. V. Palkinа, A. S. Averchuk, A. R. Esimbekova, and T. G. Ruksha. "Antitumor, toxicity and target gene expression evaluation of MiR-204-5p mimic application on melanoma b16-bearing mice." Siberian journal of oncology 21, no. 3 (2022): 61–69. http://dx.doi.org/10.21294/1814-4861-2022-21-3-61-69.

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Objective. To evaluate anti-tumor, toxic effect of miR-204-5p mimic applicaton on melanoma B-16-bearing mice followed by miR-204-5p target gene expression estimation in melanoma tumor and distant organs. Material and Methods. C57Bl/6 melanoma B-16-bearing mice were used. The animals of the experimental group were intraperitoneally injected with a 5 nM miR-204-5p miRNA simulator (mimic) on the 8th, 10th, and 12th days after melanoma B-16 cell transplantation. Based on the results of bioinformatic analysis, miR-204-5p target genes BCL2 and SIRT1 expression levels were determined by quantitative

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Zhao, Li, Jing Peng, Li Zhuang, et al. "MiR-155 promotes compensatory lung growth by inhibiting JARID2 activation of CD34+ endothelial progenitor cells." PLOS ONE 19, no. 2 (2024): e0296671. http://dx.doi.org/10.1371/journal.pone.0296671.

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Bone marrow-derived CD34-positive (CD34+) endothelial progenitor cells (EPCs) has unique functions in the mechanism of compensatory lung growth (CLG). The content of this study is mainly to describe the effect of microRNA (miR)-155 in the mechanisms of EPCs and CLG. Our study found that transfection of miR-155 mimic could promote EPC proliferation, migration and tube formation, while transfection of miR-155 inhibitor had the opposite effect. It was also found that transfection of pc-JARID2 inhibited EPC proliferation, migration and tube formation, while transfection of si-JARID2 had the opposi

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MATSUBARA, Teruhiko, Ai ONISHI, Tomomi SAITO, Daisuke YAMAGUCHI, and Toshinori SATO. "Multivalent Effect in Influenza Hemagglutinin-Binding Activity of Sugar-Mimic Peptide." KOBUNSHI RONBUNSHU 73, no. 1 (2016): 62–68. http://dx.doi.org/10.1295/koron.2015-0052.

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Wang, Xiaochuan, Yifei Wu, Peng Du, et al. "Study on the Mechanism of miR-125b-5p Affecting Melanocyte Biological Behavior and Melanogenesis in Vitiligo through Regulation of MITF." Disease Markers 2022 (November 16, 2022): 1–17. http://dx.doi.org/10.1155/2022/6832680.

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Objective. The goal was to confirm the mechanism by which miR-125b-5p influences melanocyte biological behavior and melanogenesis in vitiligo by regulating MITF. Methods. oe-MITF, sh-MITF, miR-125b-5p mimic, NC-mimic, NC-inhibitor, and miR-125b-5p inhibitor were transfected into cells by cell transfection. Western blotting was used to detect the related protein expression, qRT–PCR was used to detect miR-125b-5p and MITF expression, immunohistochemistry was used to detect the MITF-positive cells in vitiligo patients tissues, and a dual-luciferase reporter system was used to detect the target of

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Xie, H., L. Cao, L. Ye, G. Shan та W. Song. "The miR-1906 mimic attenuates bone loss in osteoporosis by down-regulating the TLR4/MyD88/NF‐κB pathway". Physiology International 107, № 4 (2021): 469–78. http://dx.doi.org/10.1556/2060.2020.00042.

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AbstractIn this study, the ability of microRNA-1906 (miR-1906) to attenuate bone loss in osteoporosis was evaluated by measuring the effects of a miR-1906 mimic and inhibitor on the cellular toxicity and cell viability of MC3T3‐E1 cells. Bone marrow-derived macrophage (BMM) cells were isolated from female mice, and tartrate-resistant acid phosphatase signalling was performed in miR-1906 mimic-treated, receptor-activated nuclear factor kappa-B (NF-κB) ligand (RANKL)-induced osteoclasts. In-vivo, osteoporosis was induced by ovariectomy (OVX). Rats were treated with 500 nmol/kg of the miR-1906 mi

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Wu, Hong-Lian, Zhen-Na Chen, Hui Zhang, Xiao-Min Zhang, and Xiao-Rong Li. "miRNA-451 regulates rhesus choroid-retinal endothelial cell function and proteome profile." International Journal of Ophthalmology 15, no. 6 (2022): 894–904. http://dx.doi.org/10.18240/ijo.2022.06.06.

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AIM: To evaluate the effect of miRNA-451 on rhesus macaque choroid-retinal endothelial (RF/6A) cell function and proteome profile. METHODS: The RF/6A cells were transfected with miRNA-451 mimic and inhibitor. The role of miRNA-451 on proliferation ability was evaluated by CCK-8 assay. Furthermore, iTRAQ quantitative proteomic analysis was applied to comprehensively illuminate the change of cellular proteins and biological function between different groups. RESULTS: In miRNA-451 overexpression group, cell proliferation of RF/6A decreased both at 24h and 48h; while in miRNA-451 inhibition group,

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Tang, Hao-Cheng, Yin-Yan Lai, Jing Zheng, Hong-Yan Jiang, and Geng Xu. "miR-223-3p Inhibits Antigen Endocytosis and Presentation and Promotes the Tolerogenic Potential of Dendritic Cells through Targeting Mannose Receptor Signaling and Rhob." Journal of Immunology Research 2020 (June 18, 2020): 1–17. http://dx.doi.org/10.1155/2020/1379458.

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Background. The role of miR-223-3p in dendritic cells (DCs) is unknown. This study is aimed at investigating the effect of miR-223-3p on the antigen uptake and presentation capacities of DCs and the underlying molecular mechanism. Methods. FITC-OVA antigen uptake and cell surface markers in bone marrow-derived DCs (BMDCs) were analyzed by flow cytometry. BMDCs were transfected with the miR-223-3p mimic or inhibitor. Cytokine levels were determined by ELISA. CD4+ T cell differentiation was determined by mixed lymphocyte culture assay. Results. OVA treatment significantly downregulated miR-223-3

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Yan, Shufang, Qinyu Shang, Haipeng Zhu, et al. "Effects of hsa-miR-28-5p on Adriamycin Sensitivity in Diffuse Large B-Cell Lymphoma." Evidence-Based Complementary and Alternative Medicine 2022 (July 13, 2022): 1–14. http://dx.doi.org/10.1155/2022/4290994.

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Background. Adriamycin (doxorubicin) is an important traditional drug that exhibits cytotoxicity in Diffuse Large B-cell Lymphoma (DLBCL). Doxorubicin affects the DLBCL cells at all stages of their cell cycle. Combined with our previous results, this study discovered that the overexpression of hsa-miR-28-5p inhibited the proliferation, promoted apoptosis, and triggered cell cycle arrest at the S-phase in DLBCL cells. However, the effect of (Homo sapiens, hsa)-microRNA (miR)-28-5p on doxorubicin sensitivity in DLBCL has not been investigated. This study aims to reveal the effects of hsa-miR-28-

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Scheiber, H., K. Lubke, D. Grutzmacher, C. G. Diskus, and H. W. Thim. "MIMIC-compatible GaAs and InP field effect controlled transferred electron (FECTED) oscillators." IEEE Transactions on Microwave Theory and Techniques 37, no. 12 (1989): 2093–98. http://dx.doi.org/10.1109/22.44127.

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Royall, Donald R., Ram J. Bishnoi, and Raymond F. Palmer. "Serum IGF-BP2 strongly moderates age's effect on cognition: a MIMIC analysis." Neurobiology of Aging 36, no. 7 (2015): 2232–40. http://dx.doi.org/10.1016/j.neurobiolaging.2015.04.003.

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Sui, H., W. Wang, and L. S. Liu. "THE PROTECTIVE EFFECT OF SELENO-GLUTATHIONE PEROXIDASE MIMIC AND PZS1 AGAINST DAMAGE." Journal of Hypertension 22, Suppl. 1 (2004): S79. http://dx.doi.org/10.1097/00004872-200402001-00334.

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Karaman, Mustafa, Nihat Çabuk, Demet Özyurt, and Özcan Köysüren. "Self-supporting superhydrophobic thin polymer sheets that mimic the nature's petal effect." Applied Surface Science 259 (October 2012): 542–46. http://dx.doi.org/10.1016/j.apsusc.2012.07.079.

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Altieri, Nicholas, and Cheng-Ta Yang. "Parallel linear dynamic models can mimic the McGurk effect in clinical populations." Journal of Computational Neuroscience 41, no. 2 (2016): 143–55. http://dx.doi.org/10.1007/s10827-016-0610-z.

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Hiraka, Kazue, Mayuko Kanehisa, Miho Tamai, et al. "Preparation of pH-sensitive liposomes retaining SOD mimic and their anticancer effect." Colloids and Surfaces B: Biointerfaces 67, no. 1 (2008): 54–58. http://dx.doi.org/10.1016/j.colsurfb.2008.07.014.

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Zabłocka, Agnieszka, Anna Urbaniak, Marianna Kuropatwa, Joanna Zyzak, Joanna Rossowska, and Maria Janusz. "Can proline-rich polypeptide complex mimic the effect of nerve growth factor?" BioFactors 40, no. 5 (2014): 501–12. http://dx.doi.org/10.1002/biof.1174.

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Okamoto, Masami. "Viscoelasticity effect of the substrate to mimic microenvironment of breast cancer cells." International Physical Medicine & Rehabilitation Journal 8, no. 3 (2023): 215–18. http://dx.doi.org/10.15406/ipmrj.2023.08.00362.

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Zhang, Jingru, Bo Lian, Yan Shang, Chun Li, and Qingkai Meng. "miR-135a Protects Dextran Sodium Sulfate-Induced Inflammation in Human Colorectal Cell Lines by Activating STAT3 Signal." Cellular Physiology and Biochemistry 51, no. 3 (2018): 1001–12. http://dx.doi.org/10.1159/000495481.

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Background/Aims: miR-135a is reduced in several cancers and has been suggested to mediate immune and inflammatory responses. However, the effect of miR-135a on inflammatory bowel diseases was obscure. This study firstly attempted to investigate the hypothesis that miR-135a alleviates dextran sodium sulfate (DSS)-induced inflammation in colonic cells and potential mechanisms are also studied. Methods: Caco-2 and HT-29 cells in this study were treated with DSS, miR-135a mimic, and S3I-201, and then CKK-8 assay was used to test cell viability. Expressions of miR-135a, cytokines, and signal transd

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Li, Leilei, Kaixuan Liang, Zhentao Hua, Min Zou, Kezheng Chen, and Wei Wang. "A green route to water-soluble polyaniline for photothermal therapy catalyzed by iron phosphates peroxidase mimic." Polymer Chemistry 6, no. 12 (2015): 2290–96. http://dx.doi.org/10.1039/c4py01716a.

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Bansal, Ruby, and R. Thomas Zoeller. "Polychlorinated Biphenyls (Aroclor 1254) Do Not Uniformly Produce Agonist Actions on Thyroid Hormone Responses in the Developing Rat Brain." Endocrinology 149, no. 8 (2008): 4001–8. http://dx.doi.org/10.1210/en.2007-1774.

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Thyroid hormone (TH) is essential for normal brain development, and polychlorinated biphenyls (PCBs) are known to interfere with TH action in the developing brain. Thus, it is possible that the observed neurotoxic effects of PCB exposure in experimental animals and humans are mediated in part by their ability to interfere with TH signaling. PCBs may interfere with TH signaling by reducing circulating levels of TH, acting as TH receptor analogs, or both. If PCBs act primarily by reducing serum TH levels, then their effects should mimic those of low TH. In contrast, if PCBs act primarily as TH a

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BALA, Ioana Alexandra, Bogdan TRICA, Florentina GEORGESCU, et al. "THE EFFECT OF A STRIGOLACTONE MIMIC ON GROWTH AND COLONY MORPHOLOGY IN PHYTOPATHOGENIC FUNGI." AgroLife Scientific Journal 10, no. 1 (2021): 36–47. http://dx.doi.org/10.17930/agl202113.

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The paper investigates the effect of a strigolactone mimic, 3-Methyl-5-(benzo[de]isoquinoline-1,3-dione-2-yloxy)-5Hfuran-2-one, bearing a naphthylamide core linked by an ether group to the furan-2-one ring, on hyphal branching and radial fungal growth of two plant pathogenic fungi, Colletotrichum acutatum CBS 112980 and Sclerotinia minor DSM 63016. Our results demonstrated that the tested mimic compound, which is easier to synthetize comparing tostrigolactone analogues, have the same effect as the synthetic analogue GR24, inducing hyphal branching stress response and inhibiting phytopathogen g

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Zheng, Wen, Xia Jin, and Bo Zhang. "The Simulation Study Based on Multi-Agents of Mobile Market." Advanced Materials Research 143-144 (October 2010): 433–38. http://dx.doi.org/10.4028/www.scientific.net/amr.143-144.433.

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The holistic simulation study is based on multi-agents to stimulate the behavior of mobile communication. The paper intents to understand the effect of the regulation on the market of mobile communication on the methodology of complex adaptive system simulation in swarm platform. The simulation was on the condition of mimic surrounding. The simulation program includes four classes of Swarm objectives. Results reveal that reasonable, ordered and co-coordinated communication market is on the state of the regulatory of duopoly. Based on the multiple agents modeling on the platform of swarm softwa

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Sonnay, Marjorie, and Felix Zelder. "Stabilizing intramolecular cobalt–imidazole coordination with a remote methyl group in the backbone of a cofactor B12–protein model." Dalton Transactions 47, no. 31 (2018): 10443–46. http://dx.doi.org/10.1039/c8dt01298a.

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Zou, Qiang, Hao-Wen Wang, Xi-Liang Di, Yuan Li, and Hui Gao. "Long noncoding RNAs HAND2-AS1 ultrasound microbubbles suppress hepatocellular carcinoma progression by regulating the miR-873-5p/tissue inhibitor of matrix metalloproteinase-2 axis." World Journal of Gastrointestinal Oncology 16, no. 4 (2024): 1547–63. http://dx.doi.org/10.4251/wjgo.v16.i4.1547.

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BACKGROUND Increasing data indicated that long noncoding RNAs (lncRNAs) were directly or indirectly involved in the occurrence and development of tumors, including hepatocellular carcinoma (HCC). Recent studies had found that the expression of lncRNA HAND2-AS1 was downregulated in HCC tissues, but its role in HCC progression is unclear. Ultrasound targeted microbubble destruction mediated gene transfection is a new method to overexpress genes. AIM To study the role of ultrasound microbubbles (UTMBs) mediated HAND2-AS1 in the progression of HCC, in order to provide a new reference for the treat

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Zhang, Feifei, Feng Tang, Xiaolun Xu, Pierre-Michel Adam, Jérôme Martin, and Jérôme Plain. "Influence of order-to-disorder transitions on the optical properties of the aluminum plasmonic metasurface." Nanoscale 12, no. 45 (2020): 23173–82. http://dx.doi.org/10.1039/d0nr06334g.

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Iserbyt, Arne, Jessica Bots, Stefan Van Dongen, Janice J. Ting, Hans Van Gossum, and Thomas N. Sherratt. "Frequency-dependent variation in mimetic fidelity in an intraspecific mimicry system." Proceedings of the Royal Society B: Biological Sciences 278, no. 1721 (2011): 3116–22. http://dx.doi.org/10.1098/rspb.2011.0126.

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Contemporary theory predicts that the degree of mimetic similarity of mimics towards their model should increase as the mimic/model ratio increases. Thus, when the mimic/model ratio is high, then the mimic has to resemble the model very closely to still gain protection from the signal receiver. To date, empirical evidence of this effect is limited to a single example where mimicry occurs between species. Here, for the first time, we test whether mimetic fidelity varies with mimic/model ratios in an intraspecific mimicry system, in which signal receivers are the same species as the mimics and m

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Uysal, Nermin Kibrislioglu, and Kubra Atalay Kabasakal. "The Effect of Background Variables on Gender DIF." European Journal of Multidisciplinary Studies 5, no. 1 (2017): 490. http://dx.doi.org/10.26417/ejms.v5i1.p490-490.

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The purpose of this study is to investigate the presence of differential item functioning (DIF) between gender groups in PISA 2015 science items in nine selected countries. Moreover, the effect of socioeconomic status, reading ability, science self-efficacy and science motivation on the presence of gender-related DIF are examined, respectively. One cluster from computer-based assessment (CBA) is taken into consideration. The countries are selected among the ones that implemented CBA, on the basis of their rank in science achievement. Multiple Indicator Multiple Causes method (MIMIC) is used in

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He, Lijie, Jing Wang, Dandan Chang, Dandan Lv, Haina Li, and Heqiang Feng. "Effect of miRNA-200b on the proliferation and apoptosis of cervical cancer cells by targeting RhoA." Open Medicine 15, no. 1 (2020): 1019–27. http://dx.doi.org/10.1515/med-2020-0147.

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AbstractObjectiveThis article aims to investigate the effect of miRNA-200b on the proliferation and apoptosis of cervical cancer cells by targeting RhoA.MethodsHeLa cells of cervical cancer were divided into five groups: blank control group, negative control group (miRNA-200b mimic NC), miRNA-200b mimic group, RhoA-negative control group, and RhoA overexpression group. Cells were collected 48 h after transfection. The expression levels of miRNA-200b were detected by RT-PCR. Target relationship between miRNA-200b and RhoA was verified by the dual-luciferase reporter assay. RhoA mRNA and protein

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Rehfeld, A., D. L. Egeberg, K. Almstrup, J. H. Petersen, S. Dissing, and N. E. Skakkebæk. "EDC IMPACT: Chemical UV filters can affect human sperm function in a progesterone-like manner." Endocrine Connections 7, no. 1 (2018): 16–25. http://dx.doi.org/10.1530/ec-17-0156.

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Human sperm cell function must be precisely regulated to achieve natural fertilization. Progesterone released by the cumulus cells surrounding the egg induces a Ca2+ influx into human sperm cells via the CatSper Ca2+-channel and thereby controls sperm function. Multiple chemical UV filters have been shown to induce a Ca2+ influx through CatSper, thus mimicking the effect of progesterone on Ca2+ signaling. We hypothesized that these UV filters could also mimic the effect of progesterone on sperm function. We examined 29 UV filters allowed in sunscreens in the US and/or EU for their ability to a

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Blut, C., J. Wilbrandt, D. Fels, E. I. Girgel, and K. Lunau. "The ‘sparkle’ in fake eyes - the protective effect of mimic eyespots in lepidoptera." Entomologia Experimentalis et Applicata 143, no. 3 (2012): 231–44. http://dx.doi.org/10.1111/j.1570-7458.2012.01260.x.

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Hoogerheide, David P., Philip A. Gurnev, Tatiana K. Rostovtseva, and Sergey M. Bezrukov. "Effect of a post-translational modification mimic on protein translocation through a nanopore." Nanoscale 12, no. 20 (2020): 11070–78. http://dx.doi.org/10.1039/d0nr01577f.

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Kennaway, D. J., and R. W. Moyer. "Serotonin 5-HT2c agonists mimic the effect of light pulses on circadian rhythms." Brain Research 806, no. 2 (1998): 257–70. http://dx.doi.org/10.1016/s0006-8993(98)00746-x.

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Tan, Chao, Bensheng Huang, Da Liu, et al. "Effect of Mimic Vegetation with Different Stiffness on Regular Wave Propagation and Turbulence." Water 11, no. 1 (2019): 109. http://dx.doi.org/10.3390/w11010109.

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Flume experiments were performed to test four plant mimics with different stiffness to reveal the effect of plant stiffness on the wave dissipation and turbulence process. The mimics were built of silica gel rod groups, and their bending elastic modulus was measured as a proxy for stiffness. The regular wave velocity distribution, turbulence characteristics, and wave dissipation effect of different groups were studied in a flume experiment. Results show that, when a wave ran through the flexible rod groups, the velocity period changed gradually from unimodal to bimodal, and the secondary wave

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Shen, Yuhua, Qingfeng Zhang, Long Chen, Anjian Xie, Xiangyun Kong, and Liangbao Yang. "Effect of Escherichia coliform on the biomineralization of calcium bilirubinate in mimic systems." Colloids and Surfaces B: Biointerfaces 65, no. 1 (2008): 11–17. http://dx.doi.org/10.1016/j.colsurfb.2008.02.008.

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Schroder, Araya K., Conor J. Loy, Fernanda Aiala, Jazmyn Rafique, Arnob Ghosh, and Lina I. Yoo. "miR-379-5p affects breast cancer cell behavior by targeting UBE2E3 ubiquitin conjugating enzyme." PLOS ONE 19, no. 12 (2024): e0310315. https://doi.org/10.1371/journal.pone.0310315.

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MicroRNAs (miRNAs) play an increasingly recognized role in modulating cancer development. Due to their function in regulating gene expression, miRNAs can suppress or promote tumorigenesis. miR-379-5p expression is downregulated in multiple human cancers, including breast and bladder cancers. However, the mRNAs targeted by miR-379-5p that promote cancer development have not been fully identified. Our goal was to identify a gene whose expression is regulated by miR-379-5p, and which may contribute to cancer development in cells where miR-379-5p expression is reduced. Bioinformatics analysis show

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Zhang, Yu, Kun Zhuang, Shanshan Yuan, et al. "Effects of mir-195 Targeted Regulation of JAK2 on Proliferation, Invasion, and Apoptosis of Gastric Cancer Cells." Computational and Mathematical Methods in Medicine 2022 (July 26, 2022): 1–8. http://dx.doi.org/10.1155/2022/5873479.

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Background. Overexpression of miR-195 can make gastric cancer cells stay in G1/G2 phase. miR-195 has been shown to inhibit gastric cancer cell replication and accelerate cell death by targeting JAK2. However, the relationship between miR-195, JAK2, and gastric cancer is not clear. Objective. To observe the effect of mir-195 regulated by JAK2 on the growth, invasion, and death of gastric cancer cells. Methods. MGC803 and NCI gastric N87 cells were introduced into the negative control sequences of miR-195 and RNA, respectively. To detect the expression of miR-195 in cells, to detect the effect o

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Guo, Yamin, Xinmiao Wu, Huimin Zhen, et al. "MicroRNA-30a-3p Influences Milk Fat Metabolism by Targeting PTEN in Mammary Epithelial Cells of Sheep." Animals 15, no. 8 (2025): 1180. https://doi.org/10.3390/ani15081180.

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Our previous investigations identified miR-30a-3p as a differentially expressed miRNA in ovine mammary tissue across sheep breeds with distinct lactation performance and different physiological stages. However, its regulatory mechanisms controlling mammary gland development and lactation remain unexplored. In this study, the effect of miR-30a-3p on the proliferation of ovine mammary epithelial cells (MECs) and the target genes of miR-30a-3p were investigated. The regulatory effects of miR-30a-3p on the expression of the target genes and the content of triglycerides in ovine MECs were also anal

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Xu, Ying, Yihua Bei, Shutong Shen, et al. "MicroRNA-222 Promotes the Proliferation of Pulmonary Arterial Smooth Muscle Cells by Targeting P27 and TIMP3." Cellular Physiology and Biochemistry 43, no. 1 (2017): 282–92. http://dx.doi.org/10.1159/000480371.

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Background/Aims: Aberrant vascular smooth muscle cell (VSMC) proliferation plays an important role in the development of pulmonary artery hypertension (PAH). Dysregulated microRNAs (miRNAs, miRs) have been implicated in the progression of PAH. miR-222 has a pro-proliferation effect on VSMCs while it has an anti-proliferation effect on vascular endothelial cells (ECs). As the biological function of a single miRNA could be cell-type specific, the role of miR-222 in pulmonary artery smooth muscle cell (PASMC) proliferation is not clear and deserves to be explored. Methods: PASMCs were transfected

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Zhao, Ruoxi, Rui Zhang, Lili Feng, et al. "Constructing virus-like SiO_x/CeO₂/VO_x nanozymes for 1064 nm light-triggered mild-temperature photothermal therapy and nanozyme catalytic therapy." Nanoscale 14, no. 2 (2022): 361–72. http://dx.doi.org/10.1039/d1nr06128c.

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Serra, Thea, Laura Anfossi, Simone Cavalera, et al. "Ochratoxin A-Imprinted nanoMIPs Prepared by Solid Phase Synthesis: Effect of Mimic Template on Binding Properties." Macromol 3, no. 2 (2023): 234–44. http://dx.doi.org/10.3390/macromol3020015.

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The solid-phase polymerization synthesis (SPPS) represents one of the most innovative approaches to the preparation of nano-sized molecularly imprinted polymers. One of its main features consists of the use of a solid support on which the template molecule is covalently grafted. It implies that the imprinting process does not involve the target molecule as is, but, rather, a structural modification of it. It is known that the rationally designed mimic N-(4-chloro-1-hydroxy-2-naphthoylamido)-(L)-phenylalanine (CHNA-Phe) is able to generate, by bulk polymerization, imprinted materials capable of

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Hmadcha, Abdelkrim. "miR-21 mimic blocks obesity in mice: A novel therapeutic option." Mol Ther Nucleic Acids 26 (July 2, 2021): 401–16. https://doi.org/10.1016/j.omtn.2021.06.019.

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MicroRNAs (miRNAs) are promising drug targets for obesity and metabolic disorders. Recently, miRNA mimics are providing a unique mechanism of action that guides the process for drug development and sets out the context of their therapeutic application. miRNA (miR)-21 expression in white adipose tissue (WAT) has been associated with obesity. We aimed to analyze miR-21 expression levels in relation to diabetes and obesity to determine the effect that miR-21 mimic has on processes involved in WAT functionality, to dissect the underlying molecular mechanisms, and to study the potential therapeutic

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