Bibliographies thématiques / Medicinal documentation

Littérature scientifique sur le sujet « Medicinal documentation »

Auteur : Grafiati
Publié le 18 mai 2024

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Articles de revues sur le sujet "Medicinal documentation"

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Devika Sukhadev, Rekka Raja et Nirubama Kumar. « Documentation of medicinal plants in niramkaithakotta hills, kerala ». Kongunadu Research Journal 9, no 2 (31 décembre 2022) : 45–59. http://dx.doi.org/10.26524/krj.2022.19.

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The present study has been carried out in Niramkaitha kotta Hills, Vallikkunnu, Malappuram District, Kerala, India to document the current floristic composition, conservation status of the study area and medicinal properties of plants .An extensive and intensive floristic survey were undertaken during December 2020 - Feb 2021 in Niramkaitha kotta hills. The area was surveyed at every visit and periodical collection of plants made from each locality. Taxonomically a total number of 91 medicinal plant species of Angiosperms distributed belonging to 45 families and 4 species of pteridophytes has been recorded from the study area of Niramkaitha kotta Hills and listed in the. Out of this 91 species 87 families belongs to Dicotyledons and 4families belongs to Monocotyledons and four species were Pteridophytes. In the life form category of the enumerated plants the majority of the species were herbs (46 species) followed by shrubs (26 species), climber (9 species) and tree (10species). Tridax procumbens L. was the most abundant species when compared to other species in the study area. In the present study out of 91 species recorded two species namely Gloriosa superba L. and Pterocarpus santalina L. f are endangered, 24 species are least concern.
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Thomas, Alphonsa, et S. Amala Divya. « Documentation of medicinal plants used by local people of Peruvannamuzhi Kozhikkode, Kerala. » YMER Digital 21, no 05 (31 mai 2022) : 1383–99. http://dx.doi.org/10.37896/ymer21.05/f2.

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The knowledge of medicinal plants is one of the greatest treasure that have been transferred from generation to generation through oral mode. The art of healing with medicinal plants is a part of Indian culture from time immemorial. A wide range of plant and plant products have been used effectively in treating various diseases. The present study undertaken documented forty five medicinal plants belonging to twenty seven families used by people of Peruvannamuzhi and adjacent villages of Kozhikode, Kerala. The field surveys and questioners carried out revealed that both herbal knowledge and plant wealth are at the brink of extinction. Key Words : medicinal plants, survey, Peruvannamuzhi, Kozhikkode
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Smekhova, I. E., L. V. Shigarova, V. D. Meteleva et E. V. Flisyuk. « Documentation of Pharmaceutical Development. Part 1. Study of the Documentation of the Site ». Drug development & ; registration 10, no 1 (25 février 2021) : 142–47. http://dx.doi.org/10.33380/2305-2066-2021-10-1-142-147.

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Introduction. The trends in the modern pharmaceutical industry demonstrate the need for proper documentation of all stages of the life cycle of a medicinal product to ensure its quality and eliminate risks to patients. Therefore, documenting pharmaceutical development, as the first stage of this cycle, is relevant. It will allow regulating technological processes, product quality indicators, as well as ensuring the integrity of the data received. It is advisable to document the pharmaceutical development taking into account the requirements established at the enterprise where the industrial production of this drug is planned.Aim. Development of documentation for pharmaceutical development within the pharmaceutical quality system of the enterprise. One of the objectives of the study was to analyze the document flow of the pharmaceutical quality system of the enterprise planning the production of suppositories for the proper development of documentation for the pharmaceutical development of a medicinal product in this dosage form.Materials and methods. During the research the following methods were used: content analysis; system analysis; sociological (survey method); SWOT analysis technology; systems approach.Results and discussion. In order to get acquainted with modern trends related to pharmaceutical development and pharmaceutical quality system, at the first stage, an analysis of the ICH (International Council on Harmonization) guidance document Quality Implementation Working Group on Q8, Q9 and Q10 Questions & Answers was carried out. An important preparatory stage for the optimal documentation of a pharmaceutical development was the study of the document flow of the pharmaceutical quality system of an enterprise planning to produce two-component suppositories. For this purpose, in the course of the research, a questionnaire was developed containing questions related to the functioning of the quality system, documentation processes and production. The analysis of the received responses made it possible to obtain information on documenting the pharmaceutical development of medicinal products, as well as to identify the main trends associated with this process within the pharmaceutical quality system.Conclusion. The documentation of the pharmaceutical quality system of the enterprise planning the production of suppositories has been analyzed. The strengths and weaknesses of the documentation are identified, a number of proposals for improving the documentation system are highlighted. Based on the results obtained, proposals will be developed for the optimal documentation of pharmaceutical development and a set of documents for an enterprise planning to produce two-component suppositories will be formed.
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Nozhkina, N. N., et O. N. Dvorskaya. « Determination of the Main Quality Indicators and Evaluation of Medicinal Films Containing Succinic Acid and Cetylpyridinium Chloride ». Medicina 10, no 3 (2022) : 85–91. http://dx.doi.org/10.29234/2308-9113-2022-10-3-85-91.

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The main quality indicators and criteria for their acceptance for a medicinal film containing succinic acid and CPC were determined in accordance with the requirements of the current regulatory documentation. The quality of the pilot batches of the medicinal film was assessed in accordance with the developed quality indicators. As a result of the research, a draft regulatory documentation for the studied dosage form was developed – "Medicinal gum film containing succinic acid and cetylpyridinium chloride".
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Sharma, Seema, Kuldeep Dogra, Kulwant Sharma, Renu Sharma et Kumar Ambrish. « Documentation of the Traditional knowledge of Some plant Species occurring in the Shilli Conservation Reserve in Solan district of Himachal Pradesh, India ». Journal of Non Timber Forest Products 27, no 4 (1 décembre 2020) : 187–90. http://dx.doi.org/10.54207/bsmps2000-2021-yiq0tz.

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A field survey was conducted in the Shilli Conservation Reserve, Solan, Himachal Pradesh to collect and document the medicinally important plant species. Further intensive surveys were conducted in the villages around the conservation reserve to collect the information on their traditional medicinal uses by the local inhabitants. The paper enumerates the traditional medicinal uses of 45 plant species belonging to 33 families along with their botanical names, local names, habit and part used for the treatment of various ailments by the local communities around the Shilli Conservation Reserve in the Solan district of Himachal Pradesh.
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Vishwakarma, Satya Prakash, R. K. Prajapati, Yogesh Dubey, Sarita Bodalkar et Amit Prakash Nayak. « Documentation of Medicinal plants of Moist Deciduous Forest of Amarkantak Region, Madhya Pradesh, India ». International Journal of Environment and Climate Change 13, no 9 (27 juillet 2023) : 2234–55. http://dx.doi.org/10.9734/ijecc/2023/v13i92457.

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The present investigation carried out on “Documentation of Medicinal plants of Moist Deciduous Forest of Amarkantak Region, Madhya Pradesh”. The study was conducted in Anuppur forest division during 2021-2022. The current investigation is focused on the medicinal plants that may be found in the Amarkantak region. The documentation of medicinal plant was carried out through stratified random sampling method. In this area, documentation of many types of vegetation (trees, shrubs, and herbs) has been documented. A total 66 plants were collected from different parts of the study area; those include 28 speciesof tree, 10 species of shrub and 28 species of herb. The documented plant species consists of 28 families of 23 genera of tree, 10 families of 10 genera of shrub and 28 families of 28genera of herb. Floristic composition and most dominant families were found highest for Fabaceae followed by Malvaceae, Moraceae, Phyllanthaceae etc. Documentation of medicinal plants is the only method to ensure that future generations can access the essential information required to use plant resources. Traditional medicine and ethno-botanical knowledge can preserve cultural practices and the environment, promote local health care, and create new medicinal products. Result show that most of the plants studied are effective against various illnesses, alone or mixed with other plants. Therefore, it is recommended that strategies be implemented to preserve and protect significant species from growing extinct in their native habitat.
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Subedi, Yushika, et Ronika Thapa. « Documentation of Ethnobotanically Rich, Neglected and Underutilized Wild Edible Species of Kathmandu ». International Journal of Current Microbiology and Applied Sciences 11, no 4 (10 avril 2022) : 56–64. http://dx.doi.org/10.20546/ijcmas.2022.1104.009.

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On picturization and trend analysis of declining biodiversity status of Kathmandu Valley because of the intensifying globalization and natural resource utilization, it can be concluded that the present need of the valley is biodiversity conservation and importantly their documentation. In such context, biodiversity conservation and their documentation has become essential. In regards to documentation of biodiversity, 110 medicinal plants collected by the researchers themselves from the Ramkot region of Sitapaila located in Kathmandu valley has been recorded and enlisted in this paper. Some of the major medicinal importance along with quality attributes of the plant species have been presented in this paper.
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Fantini Malavazi Camargo, Giulia, Patricia De Aguiar Amaral, Angela Erna Rossato et Vanilde Citadini-Zanette. « Plantas Medicinais e Alimentícias para Tratamento de Doenças Gastrointestinais : Estudo de Caso ». Ensaios e Ciência C Biológicas Agrárias e da Saúde 26, no 3 (11 novembre 2022) : 261–69. http://dx.doi.org/10.17921/1415-6938.2022v26n3p261-269.

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O conhecimento popular sobre os vegetais para uso medicinal e alimentício cresce exponencialmente, sendo repassado principalmente através de gerações. Este estudo objetivou relatar o saber popular sobre espécies medicinais utilizadas contra doenças do trato gastrointestinal (TGI) e seus potenciais alimentícios. Realizou-se um estudo minucioso com uma conhecedora de plantas medicinais, reconhecida por seus saberes por moradores do município de Cocal do Sul, SC. Foi aplicado a ela um formulário sobre as plantas indicadas para o tratamento de doenças no TGI (parte usada, formas de preparo e aplicação medicinal/alimentícia). Foram registradas 17 espécies pertencentes a 17 gêneros e a 12 famílias botânicas. Todas as 17 espécies são para uso medicinal e, dessas, 15 também são alimentícias. As folhas das espécies foram as mais utilizadas para fins medicinais, na forma de chá ou infusão e, de acordo com a preparação, deu-se destaque às saladas e sucos na forma de alimento. Das espécies indicadas como medicinais nove são validadas pela Agência Nacional de Vigilância Sanitária (ANVISA), sendo duas nativas do Brasil, remetendo à necessidade de mais estudos científicos sobre o potencial medicinal de espécies nacionais. Do total, cinco das espécies foram categorizadas como plantas alimentícias não convencionais (PANC). O presente estudo confirma o saber popular/tradicional sobre as plantas medicinais e alimentícias, contribuindo de forma concisa sobre informações dessas espécies no TGI. Palavras-chave: Fitoterapia. Plantas Alimentícias. Conhecimento Popular e Tradicional. Sistema TGI. Abstract Folk knowledge about plants for medicinal and food use grows exponentially, being reposted mainly through generations. This study aims to highlight the ethno-medicinal information regarding medicinal plants, their nutritional properties and how they are used for treating various Gastrointestinal diseases (GI diseases). A detailed study was carried out with an expert on medicinal plants, recognized locally by people of the municipality of Cocal do Sul (Santa Catarina) for her herbal knowledge. Data regarding the treatment of GI diseases with wild vegetables were collected using a questionnaire (i.e., which plant resources are use and how are they prepared). Seventeen species belonging to seventeen genera and twelve botanical families were mentioned. All plants mentioned are medicinal and fifteen out of them are edible. The leaves are mostly used medicinally, in the form of tea or infusion and, according to their food preparation culture, it is necessary to use them mostly on salads and juices. The Brazilian Health Regulatory Agency (ANVISA) approves only nine of the species indicated as medicinal, two of which are native to Brazil. Five of these species have been qualified in Non-Conventional Food Plants (PANC). These numbers show that further documentation of traditional knowledge of native medicinal flora is needed. The present study confirms the popular/traditional knowledge about medicinal and edible plants, contributing in a concise way to information about these species in the TGI. Keywords: Phytotherapy. Edible Plants. Folk and Traditional Knowledge. GI Diseases System.
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Schlage, Christina, C. Mabula, R. L. A. Mahunnah et M. Heinrich. « Medicinal Plants of the Washambaa (Tanzania) : Documentation and Ethnopharmacological Evaluation ». Plant Biology 2, no 1 (janvier 2000) : 83–92. http://dx.doi.org/10.1055/s-2000-296.

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Bhattacharyya, Rajasri, Sabita Bhattacharya et Siddhartha Chaudhuri. « Conservation and documentation of the medicinal plant resources of India ». Biodiversity and Conservation 15, no 8 (juillet 2006) : 2705–17. http://dx.doi.org/10.1007/s10531-005-6974-4.

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Thèses sur le sujet "Medicinal documentation"

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Saha, Manas Ranjan. « Medicinal and molecular documentation of some members of mimosaceae and their microsymbionts ». Thesis, University of North Bengal, 2017. http://ir.nbu.ac.in/hdl.handle.net/123456789/2557.

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Vieira, Sandra Filipa Simões Fernandes. « Product quality and compliance in the pharmaceutical industry ». Master's thesis, Universidade de Aveiro, 2014. http://hdl.handle.net/10773/15680.

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Mestrado em Biomedicina Farmacêutica
This thesis aims to highlight the importance of a Product Quality & Compliance department in a Pharmaceutical Industry, on the good performance of company's activities and the achievement of their goals and mission. Despite the wide activities performed by this Department, the purpose of this work will be completed by describing only some of their reponsibilities. The tasks described are specifically the ones I have been performing throughout my professional experience at Bluepharma - Pharmaceutical Industry, SA, initiated in June 2012 in the Quality Assurance Department until today in the currently named Product Quality & Compliance department. This thesis is structured into 4 parts. The first chapter is an introduction to this thesis, and includes its context and objectives, followed by a brief overview of the state-of-the art in the pharmaceutical industry, including the market environment, the regulatory environment and quality requirements. A small presentation of the company and the department where were and still are developed my professional activity is also made in this chapter. In the following chapter are described the main tasks performed, the complementary activities and key skills acquired throughout this professional experience. A discussion and conclusion is presented at the end, including an analysis of the reported activities, main difficulties encountered its role and importance in the company performance as well as the skills acquired during this work experience.
A presente tese tem como principal objectivo realçar a importância do trabalho desenvolvido num departamento de Qualidade de Producto & Compliance numa Indústria Farmacêutica no bom desempenho das actividades da empresa e no cumprimento dos seus objetivos e missão. Apesar da actividade deste departamento ser muito vasta o objectivo deste trabalho será cumprido através da descrição de algumas das tarefas executadas no âmbito deste. As tarefas descritas são, mais concretamente, as desempenhadas ao longo da minha experiência profissional na Bluepharma - Indústria Farmacêutica, S.A., iniciada em Junho de 2012 no departamento de Garantia da Qualidade, tendo continuidade até aos dias de hoje no agora designado departamento de Qualidade do Produto e Compliance. Esta dissertação está estruturada em 4 partes. No primeiro capítulo é feita uma introdução ao presente trabalho, com a sua contextualização e objetivos, seguindo-se uma breve abordagem do estado-da-arte da indústria farmacêutica, nomeadamente do contexto de mercado, do ambiente regulamentar e dos requisitos de qualidade. Neste capítulo é ainda apresentada a empresa e o departamento onde tem vindo a ser desenvolvida a minha atividade profissional. No capítulo seguinte são descritas as tarefas e atividades principais desempenhadas, as atividades complementares e as principais competências adquiridas ao longo desta experiência profissional. No final é apresentada uma discussão e conclusão, incluindo uma análise das atividades desenvolvidas, principais dificuldades sentidas, do papel e relevância das tarefas desenvolvidas no contexto global da empresa bem como das competências adquiridas durante esta experiência profissional.
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Rüter, Anders. « Disaster medicine- performance indicators, information support and documentation : A study of an evaluation tool ». Doctoral thesis, Linköpings universitet, Institutionen för biomedicin och kirurgi, 2006. http://urn.kb.se/resolve?urn=urn:nbn:se:liu:diva-7990.

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The science of disaster medicine is more a descriptive than analytical type. Research, in most instances, has not employed quantitative methods and there is very sparse knowledge based on analytical statistics. One consequence of this is that similar mistakes are repeated over and over. Lessons that should be learned are merely observed. Moreover, there are almost no practical or ethical ways in which randomised controlled studies can be performed. The management, command and control of situations on different levels of hierarchy has eldom been evaluated and there have been no standards against which performance can be evaluated. Furthermore, the documentation of decisions and staff work is rarely sufficient enough to evaluate command and control functions. Setting standards that may be used as templates for evaluation and research is an issue that is constantly being addressed by leading experts in the field of disaster medicine and this is also an important issue that is expressed in the Utstein Template. Swedish National Board of Health and Welfare, templates of performance indicators were developed. These were tested on reports available from incidents, and our conclusion was that documentation in this form was not adequate enough for use in this method of evaluation. Documentation must be improved and data probably need to be captured and stored with the help of information systems. A template developed for the evaluation of medical command and control at the scene was tested in standardised examinations. When using this template in this setting it was possible to obtain specific information on those aspects of command and control that need to be improved. An information system using on-line Internet technique was studied twice. The first study concluded that in spite of technical disturbances the system was acceptable to the organisation but could not yet be recommended for use during major incidents. The second study concluded that the retrieval of information was, in all respects not as good as the control system, a conventional ambulance file system. In a study of staff procedure skills during training of management staffs in command and control it was concluded that documentation during training sessions was not adequate and this lack of staff procedure skills could possibly be a contributing factor to the fact that lessons in command and control are not learned from incidents. Conclusions in thesis are that measurable performance indicators can be used in the training of command and control. If performance indicators are to be used in real incidents and disasters, functioning information systems have to be developed. This may lead to a better knowledge of command and control and could possibly contribute to a process where lessons are learned and mistakes are not repeated.
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Rüter, Anders. « Disaster medicine- performance indicators, information support and documentation : a study of an evaluation tool / ». Linköping : Linköping University, 2006. http://urn.kb.se/resolve?urn=urn:nbn:se:liu:diva-7990.

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Cloete, Philip G. « An evaluation of documentation of endotracheal intubation in Cape Town emergency centres ». Master's thesis, University of Cape Town, 2010. http://hdl.handle.net/11427/10183.

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We undertook a retrospective case review of medical records in two regional hospitals in Cape Town. All adult patients intubated in the EC during the 6 months 1 July to 31 December 2008 were included. A single researcher assessed the case notes to assess documentation of specific procedural criteria: indication for intubation, drugs & doses, endotracheal tube size, laryngoscopy, insertion depth, securing method, position confirmation, ventilator settings and complications. General medical documentation including demographics and legibility of physician name were also assessed. Results are presented using basic descriptive statistics of the 32 criteria analysed.
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Bentley, Thomas D. « The Impact of an Electronic Discharge Instruction Application on the Quality of Discharge Instruction Documentation ». The Ohio State University, 1997. http://rave.ohiolink.edu/etdc/view?acc_num=osu1393342438.

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von, Michaelis Carol. « Health Care Team Members' Perceptions of Changes to an Electronic Documentation System ». ScholarWorks, 2016. https://scholarworks.waldenu.edu/dissertations/2701.

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Policy makers view electronic medical records as a way of increasing efficiency in the U.S. health care system. However, hospital administrators may not have the clinical background to choose a documentation system that helps the health care team safely increase efficiency. The purpose of this case study was to examine health care team members' attitudes and perceptions of quality of care and efficiency amid a documentation system change. The theory of change was the theoretical foundation for the study. The 6 research questions were designed to elicit information about what the health care team experienced when a documentation system changed and how the change affected health care workers' stress level, chance of medical errors, ability to deliver quality care, and attitudes about hospital efficiency. Semi-structured interviews were conducted with the 15 members of a health care team who volunteered from the group and met the inclusion criteria for the study (i.e., employed during the documentation system change). The participants represented all aspects of the health care team to create a bounded case. The interview responses were hand coded to find common themes among the participants. Most participants revealed that the implementation of the new system increased their efficiency and the quality of care they offered to patients. Participants felt that the training and implementation of the system was inadequate and not specific enough for their group. By providing health care administrators with more information about the health care teams' perceptions during a change in documentation systems, they may be able to improve implementation of a new system, creating more sustainable change with less negative impact.
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Onyirimba, Esther. « Standardized Clinical Guideline for Assessment, Documentation, and Treatment of Statins ». ScholarWorks, 2019. https://scholarworks.waldenu.edu/dissertations/7499.

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The purpose of this project was to develop a practice guideline for screening patients at risk for cardiovascular disease, educate the staff at the site about the guideline, and implement the guideline at a primary care clinic. The intention was to identify and treat patients at risk for cardiovascular disease to prevent occurrence of heart disease. Cardiovascular disease includes hypertension, coronary heart disease, heart failure, and stroke. Coronary heart disease is one of the leading causes of death in the Western world. The local practice problem and focus of this project was underprescribed statin therapy for patients at risk for developing heart disease at a clinic in the southern United States. The practice-focused question that guided this project explored whether an evidence-based clinical guideline that might impact the prescription of statins for the prevention of cardiovascular disease would be approved for implementation in a primary care clinic serving adult and geriatric patients. The appraisal of guidelines for research and evaluation and the Fineout-Overholt model were used to guide this project. Sources of evidence to meet the purpose of this project were obtained from the literature and scholarly articles. The results of the presentation to the expert panel indicated that this clinical practice guideline would be implemented at the project site and would be used by nurse practitioners and physicians. The implications of this project for positive social change might include improved management of patients who are at risk for heart disease and a decrease in premature deaths related to cardiovascular disease.
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Zurgani, Emad K. A. « Documentation of the body transformations during the decomposition process : from the crime scene to the laboratory ». Thesis, University of Huddersfield, 2018. http://eprints.hud.ac.uk/id/eprint/34690/.

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Forensic science is defined as the application of scientific or technical practices to the recognition, collection, analysis, and interpretation of evidence for criminal and civil law or regulatory issues. A combination of computer science in the field of 3D reconstruction and molecular biology science and techniques were employed in this research aims to document and record a complete picture of the body decomposition process including the changes of the microbiome over the decomposition process. In this thesis, the possibility to reconstruct the crime scene and the decomposition process was investigated. In addition, a 3D model aiming to integrate the biological and thanatological information was generated. The possibility of utilising Autodesk 123D Catch software as a new tool for 3D reconstruction of a crime scene was thoroughly evaluated. First experiments demonstrated that the number of photos required to obtain the best result was specified to be from 20 to 30 photos as a minimum. In addition, significant experiments were performed in different conditions of sizes, locations, and different involved materials. The measurements were obtained from the models using the same software were compared with the real measurements of the tested objects. The result of the correlation between real and estimated measurements showed a very strong agreement ranging from 0.994 to 1.000. With reference to the documentation of the decomposition process, there are different factors, intrinsic and extrinsic, have been reported affecting the decomposition of a carrion/body. These factors mainly interact with the rates of the biological and chemical reaction happening after death. The biological reactions are mainly due to the activity of microorganism and insects. Pigs (Sus scrofa domesticus) were used as a model for human studies and the results obtained have been applied to other mammals without considering the effect of fur on the decomposition process and on the insect and microbial colonisation. In order to investigate this point, rabbits (Oryctolagus cuniculus) with and without fur were used in two sets of experiments at Huddersfield in summer 2014 and in spring 2015. The results obtained in this study showed a similarity of the decomposition stages between animals with and without fur. However, the decomposition process was faster during the summer due to the fast of insect colonisation and activity. In addition, the entomological data collected during the summer and spring experiments were demonstrated that the same taxa nearly were present in both seasons, except Hydrotaea (Diptera, Muscidae), which was presented only in the summer experiment, moreover, only one sample of Lucilia sericata (Calliphoridae) was detected in the spring season. Differences in colonisation time were observed only in spring experiment; animals without fur were colonised two days before animals with fur. The season could have affected the insect’s activity and the spread of the decomposition volatiles. The microbial communities during the decomposition process were investigated using BIOLOG EcoPlateTM and the hypervariable V1-3 region of 16S rRNA gene was used for their molecular identification based on pyrosequencing. Eurofins Genomic Operon using 454-GS Junior pyrosequencing platform (Roche) carried out these analyses. The functional diversity of the bacterial communities on all carcasses samples showed a considerable variability depending on the stage of the decomposition and the sampling region (Oral cavity, skin and interface-sand-carrion) in both seasons. Furthermore, over the molecular analyses of bacterial communities at the phylum level, four main phyla of bacteria were detected among analysed carrion during the decomposition process. These phyla were changed significantly during the stages of the decomposition and between sampling regions. While no difference was observed due to presence or absence of fur. On the other hand, the analysis at the family level was able to highlight differences at the temporal scale but as well as carrion with and without fur. The statistical analysis results showed a significant difference in the bacterial community family distribution among the presence of fur and among the decomposition stages, with significant differences among sampling regions and seasons.
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Castanheiro, Ana Margarida de Almeida. « Medicina de abrigo em casos de suspeita de maus-tratos a animais de companhia ». Master's thesis, Universidade de Lisboa, Faculdade de Medicina Veterinária, 2017. http://hdl.handle.net/10400.5/14362.

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Dissertação de Mestrado Integrado em Medicina Veterinária
É cada vez mais indiscutível a necessidade do envolvimento das associações zoófilas e instituições de abrigo no resgate, alojamento, provisão de cuidados médico-veterinários, garantia de bem-estar e adoção responsável. Inevitavelmente, o Médico Veterinário que colabora com Abrigos irá lidar com os aspetos médicos de várias formas de maus-tratos e, consequentemente, com as investigações judiciais que estes despoletam. O percurso do animal de companhia suspeito de ser vítima pode ser longo e atravessa geralmente quatro fases: a investigação do local do crime, o exame clínico forense, a estadia no abrigo e a colocação para adoção. Durante este percurso, o animal é, simultaneamente, um ser vivo, com necessidades inerentes a essa condição, e prova do crime de que foi vítima que, como tal, tem de ser preservada. Por isso, é necessário aliar a prestação de cuidados ao animal em ambiente próprio, pondo em prática os princípios da Medicina de Abrigo, à preservação de provas, conseguida através da aplicação dos princípios da Medicina Forense. Assim, paralelamente ao exame clínico, diagnóstico, tratamento e alojamento do animal, tem de haver registos escritos e/ou fotográficos do estado de saúde, dos tratamentos instituídos, da alocação e da evolução clínica deste. Na presente dissertação são apresentados seis casos clínicos de animais suspeitos de serem vítimas de maus-tratos observados no decorrer do estágio e acompanhados desde a apresentação inicial na clínica veterinária até à sua estadia no Abrigo ou adoção. A experiência adquirida com estes casos, em conjunto com informação disponível na literatura, levou à criação de uma proposta de guia de atuação em casos de maus-tratos a animais de companhia destinado a facilitar todo o processo a Médicos Veterinários de Abrigo e associações zoófilas.
ABSTRACT - Shelter Medicine in cases of suspected pet animal maltreatment - The need to involve humane organizations and shelters in the rescue, housing, provision of medical veterinary care, welfare guarantee and responsible adoption is increasingly unquestionable. Inevitably, Veterinarians who collaborate with shelters will deal with the medical aspects of various forms of animal mistreatment and, consequently, with the legal investigations triggered by it. The course of a pet animal suspected of being a victim of maltreatment can be long and usually goes through four phases: crime scene investigation, forensic clinical exam, shelter stay and placement for adoption. During this, the animal is simultaneously a living being, with needs inherent to that condition, and proof of the crime of which it was a victim and that, as such, must be preserved. Therefore, it is necessary to combine animal care in a shelter environment, putting into practice the principles of Shelter Medicine, and the preservation of evidence achieved through the application of the principles of Forensic Medicine. Thus, in parallel with the clinical examination, diagnosis, treatment and housing of the animal, there must be written and/or photographic records of the animal‟s health, treatments instituted, allocation and clinical evolution. In this thesis, six clinical cases of animals suspected of being victims of maltreatment, observed during the internship and followed from the initial presentation at the veterinary clinic to their shelter stay or adoption, are presented. The experience gained with these cases, together with information available in literature, led to the creation of a proposal for an action guide on how to deal with cases of animal maltreatment to facilitate the whole process to Shelter Veterinarians and humane organizations.
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Livres sur le sujet "Medicinal documentation"

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1961-, Lang Rick, dir. Documentation : Field guide. Boston : Jones and Bartlett, 2000.

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Prehospital documentation : A systematic approach. Englewood Cliffs, NJ : Brady, 1992.

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RN, Snyder John, dir. EMS documentation. Upper Saddle River, N.J : Brady/Pearson/Prentice Hall, 2009.

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National Institutes of Health (U.S.). PubMed Central. et National Center for Biotechnology Information (U.S.), dir. My NCBI help documentation. [Bethesda, Md.] : NCBI, 2004.

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Montone, Deborah. Power building in documentation. Philadelphia : Saunders, 1998.

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Dacey, Bill. Evaluation and management coding and documentation guide. 5e éd. Reston, VA : St. Anthony Pub./Medicore, 2002.

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Bryan, Laura. Advanced medical transcription : Critical thinking and healthcare documentation. Boston : Pearson, 2013.

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Hand, Camp Nancy, dir. Nursing documentation : A nursing process approach. 3e éd. St. Louis : Mosby, 1999.

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Iyer, Patricia W. Nursing documentation : A nursing process approach. St. Louis : Mosby-Year Book,U.S., 1991.

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Hand, Camp Nancy, dir. Nursing documentation : A nursing process approach. St. Louis : Mosby Year Book, 1991.

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Chapitres de livres sur le sujet "Medicinal documentation"

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Mukherjee, Tapan. « Documentation and Protection of Traditional Knowledge ». Dans Medicinal Plants : Biodiversity, Sustainable Utilization and Conservation, 135–42. Singapore : Springer Singapore, 2020. http://dx.doi.org/10.1007/978-981-15-1636-8_8.

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Teoh, Eng Soon. « The Randomized Clinical Trial and the Documentation of Side Effects ». Dans Medicinal Orchids of Asia, 729–33. Cham : Springer International Publishing, 2016. http://dx.doi.org/10.1007/978-3-319-24274-3_24.

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Sangma, Merril N., Kalkame Ch Momin et Shivani Dobhal. « Ethonobotanical Documentation of Medicinal Plant Genetic Resources of West Garo Hills, Meghalaya ». Dans Addressing the Climate Crisis in the Indian Himalayas, 179–238. Cham : Springer Nature Switzerland, 2024. http://dx.doi.org/10.1007/978-3-031-50097-8_8.

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Nahler, Gerhard. « documentation ». Dans Dictionary of Pharmaceutical Medicine, 54. Vienna : Springer Vienna, 2009. http://dx.doi.org/10.1007/978-3-211-89836-9_408.

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Nahler, Gerhard. « batch documentation ». Dans Dictionary of Pharmaceutical Medicine, 13. Vienna : Springer Vienna, 2009. http://dx.doi.org/10.1007/978-3-211-89836-9_107.

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Nahler, Gerhard. « prestudy documentation ». Dans Dictionary of Pharmaceutical Medicine, 145. Vienna : Springer Vienna, 2009. http://dx.doi.org/10.1007/978-3-211-89836-9_1111.

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Nahler, Gerhard. « pretrial documentation ». Dans Dictionary of Pharmaceutical Medicine, 146. Vienna : Springer Vienna, 2009. http://dx.doi.org/10.1007/978-3-211-89836-9_1117.

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Baker, Alva, et Leonard Gelman. « Documentation and Coding ». Dans Long-Term Care Medicine, 285–97. Totowa, NJ : Humana Press, 2010. http://dx.doi.org/10.1007/978-1-60761-142-4_14.

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Ahne, Sieglinde, Thomas Ahne et Michael Bohnert. « Documentation of Injuries ». Dans Forensic aspects in emergency medicine, 15–18. Berlin, Heidelberg : Springer Berlin Heidelberg, 2023. http://dx.doi.org/10.1007/978-3-662-65949-6_3.

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Baker, Alva S., et Leonard Gelman. « Documentation and Coding ». Dans Post-Acute and Long-Term Medicine, 291–305. Cham : Springer International Publishing, 2016. http://dx.doi.org/10.1007/978-3-319-16979-8_17.

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Actes de conférences sur le sujet "Medicinal documentation"

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Cheryatova, Yu S. « Features of the anatomy of the leaves of Laurocerasus officinalis M. Roem. » Dans Растениеводство и луговодство. Тимирязевская сельскохозяйственная академия, 2020. http://dx.doi.org/10.26897/978-5-9675-1762-4-2020-80.

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The article presents the results of microscopic analysis of the leaves of L. officinalis. The main anatomical and diagnostic features that can be used in identifying and evaluating the authenticity of medicinal plant raw materials are established. Analysis of the anatomical structure showed that the leaves of L. officinalis are dorsoventral; the leaf plastic is hypostomatic, and the stomatal apparatus is anomocytic. The main vein of the leaf blade and petiole is represented by a bicollateral conducting bundle. Idioblasts represented by round- shaped essential oil cells were first identified in the columnar and spongy mesophyll of the leaf and petiole. Single diamond-shaped crystals and calcium oxalate druses were also found in the leaves. The information obtained can serve as a basis for the development of the section "Microscopy" in the draft regulatory documentation.
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Cavagnini, Gianluca, Giovanna Sansoni et Marco Trebeschi. « Using 3D range cameras for crime scene documentation and legal medicine ». Dans IS&T/SPIE Electronic Imaging, sous la direction de J. Angelo Beraldin, Geraldine S. Cheok, Michael McCarthy et Ulrich Neuschaefer-Rube. SPIE, 2009. http://dx.doi.org/10.1117/12.806191.

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Lhotska, Lenka. « Multi-Agent System as a Platform for Management of Medical Documentation ». Dans 2007 29th Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE, 2007. http://dx.doi.org/10.1109/iembs.2007.4353125.

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Lazarević, Zlatko. « Sistem cevne zračne pošte UKCL, MF.ZTM, OI pridobitev dragocenega časa pri upravljanju delovnega procesa, ki zelo vpliva na kakovost obravnave bolnika in ima pomembno vlogo pri varnosti zaposlenih in bolnikov (COVID epidemija) ». Dans Values, Competencies and Changes in Organizations. University of Maribor Press, 2021. http://dx.doi.org/10.18690/978-961-286-442-2.37.

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In the health sector, one of the biggest questions of modern time is the way of cutting cost while maintaining the same quality of service. Abroad, the use of pipe mail for the purpose of solving internal logistics and with that providing quality and adequacy of products and direct cut of costs related with the work force, is already widely present in hospitals. Transport with the use of pipe mail enables fast, safe and foremost economic content transfer. Hospitals abroad use the pipe mail mostly for: - transport of samples (swabs, blood, tissues) to laboratories, - transport of blood for the surgeries in operation rooms from the central blood bank, - transport of medicine from central pharmacy for surgeries in operation rooms or the need of different departments, - transport of documentation between departments and laboratories, - transport of lab test results to the department that ordered for that test. Pipe mail enables centralization – existence of one central laboratory, who takes care of all the necessary analysis, which directly means: - savings in space, - direct saving in the cost of pay due to the lowering number of employees or their redeployment, - higher efficiency (individual documentation processing, which directly means higher productivity based on the reduction of wasted time and waiting for documentation), - information renewal of processes, - reliability, timeliness and order, most importantly from the point of view of the patient, who will save unnecessary waiting time, from which most psychologically related issues arise, - the system is computer controlled and statistics are available to the system administrator at any time, - - Pipeline airmail has a significant impact on the safety of both employees and patients during an epidemic.
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Sansoni, Giovanna, Franco Docchio, Marco Trebeschi, Marco Scalvenzi, Gianluca Cavagnini et Cristina Cattaneo. « Application of three-dimensional optical acquisition to the documentation and the analysis of crime scenes and legal medicine inspection ». Dans 2nd IEEE International Workshop on Advances in Sensors and Interfaces, IWASI 2007. IEEE, 2007. http://dx.doi.org/10.1109/iwasi.2007.4420038.

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Astudillo, Boris, Jonathan González, Julio Mora, Cristian Bastidas et Erick Vera. « 3D Prototype of an Interactive Adding Machine to Improve Basic Numerical Skills ». Dans 10th International Conference on Human Interaction and Emerging Technologies (IHIET 2023). AHFE International, 2023. http://dx.doi.org/10.54941/ahfe1004018.

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3D printing in industries like medicine and education has led to major improvements in designing, developing, and printing useful models, including body prostheses and educational toys. The 3D printer's commercialization has risen thanks to more manufacturers, models, and reasonably priced equipment. As a result, prototypes and gadget creation have merged cutting-edge design techniques like gamification and electronic components, allowing accessibility and interactive and enjoyable devices. This paper describes the design, production, implementation, operation, codification, and printing of a 3D prototype of an interactive adding machine to improve basic numerical skills and help children and others with cognitive disabilities learn easier or lessen distractions. The prototype and all the necessary documentation are available for anyone to replicate. The paper also discusses difficulties encountered during the design process and proposes future improvements for the next version.
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Ali, N., M. Piodena-Aportadera, R. Chong, N. Roslan, E. Fan et E. Ho. « P44 Improving advance care planning (ACP) documentation in frequent department of geriatric medicine (GRM) admitters with dementia in an asian hospital ». Dans ACP-I Congress Abstracts. British Medical Journal Publishing Group, 2019. http://dx.doi.org/10.1136/spcare-2019-acpicongressabs.127.

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Bukhtiyarov, I. V., E. P. Kakorina et S. S. Zemlyakova. « IMPROVING THE STATISTICAL REPORTING OF MEDICAL ORGANIZATIONS IN THE RUSSIAN FEDERATION ». Dans The 16th «OCCUPATION and HEALTH» Russian National Congress with International Participation (OHRNC-2021). FSBSI “IRIOH”, 2021. http://dx.doi.org/10.31089/978-5-6042929-2-1-2021-1-92-96.

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Abstract. All management decisions in the healthcare are based on reliable data from medical accounting and reporting. Aim. Improve reporting forms in order to optimize accounting and reporting. Materials and methods. One of the main statistical forms of medical reporting that makes it possible to analyze indicators of the health status of workers and the activities of medical organizations in occupational medicine in the Russian Federation is the Form No. 30 “Information about a medical organization”. Results. The indicators analysis of the activities of medical organizations in the Russian Federation providing occupational health care was carried out on the basis of the Form No. 30 “Information about a medical organization”. The reporting forms about the examinations of occupational suitability and examinations of the connection between the disease and the occupation in the Russian Federation have been also developed and improved. The data analysis of medical organizations in the system for accounting and analyzing of occupational diseases «Occupational medicine» posted on the web-site http://profstat-irioh.ru is also carried out. Conclusion. It is proposed to improve the reporting documentation in order to optimize accounting and reporting if necessary. It is also proposed to keep statistics on the mandatory preliminary and periodic medical examinations for workers employed in jobs with harmful and (or) hazardous working conditions in the federal statistical form No. 1-zdrav “Information about the health care organizations”.
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Arora, Saksham, et Inas S. Khayal. « Enhanced Identification of Care Preference Documentation in Patients' Discharge Summaries Using Pre-Trained Large Language Models ». Dans 2024 IEEE First International Conference on Artificial Intelligence for Medicine, Health and Care (AIMHC). IEEE, 2024. http://dx.doi.org/10.1109/aimhc59811.2024.00007.

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Winter, Jan, Marc Schwering, Benedikt Rauscher, Florian Heigwer et Michael Boutros. « Abstract A10 : CRISPR-AnalyzeR (caR) : Web-based, interactive and exploratory analysis and documentation of pooled CRISPR/Cas9 screens ». Dans Abstracts : AACR Precision Medicine Series : Opportunities and Challenges of Exploiting Synthetic Lethality in Cancer ; January 4-7, 2017 ; San Diego, CA. American Association for Cancer Research, 2017. http://dx.doi.org/10.1158/1538-8514.synthleth-a10.

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Rapports d'organisations sur le sujet "Medicinal documentation"

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Webb, James T. Documentation for the USAF School of Aerospace Medicine Altitude Decompression Sickness Research Database. Fort Belvoir, VA : Defense Technical Information Center, mai 2010. http://dx.doi.org/10.21236/ada521198.

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Kwesiga, Victoria, Zita Ekeocha, Stephen Robert Byrn et Kari L. Clase. Compliance to GMP guidelines for Herbal Manufacturers in East Africa : A Position Paper. Purdue University, novembre 2021. http://dx.doi.org/10.5703/1288284317428.

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With the global increase in the use of traditional and complementary remedies for the prevention and treatment of illness, the quality and safety of these medicines have become a significant concern for all regulatory authorities. Herbal medicines are the most commonly used form of traditional and complementary medicines in the world and the efficacy and safety of herbal medicines, like conventional medicines, largely depends on their quality from planting to harvesting, preprocessing and final processing. Due to the inherent complexity of herbal medicines, often containing an array of active compounds, the primary processing of herbal medicines has a direct influence on their quality. Quality concerns are the reason why the medicines regulatory agencies insist that manufacturers of medicines strictly follow Good Manufacturing Practices since it is an essential tool to prevent instances of contamination, mix-ups, deviations, failures and errors. However, a strict application of GMP requirements is expensive and would drive the prices of the manufactured products up. As a result, a maturity level grading of facilities is proposed as a way of justifying the costs incurred for manufacturers desiring to reach a broader market and investing in continuous improvement. 36 Good Manufacturing Practice (GMP) inspection reports of local herbal manufacturers conducted by National Drug Authority were analyzed to establish the type and extent of deficiencies to GMP requirements for local herbal manufacturers in Uganda. The different GMP chapters and related sub-parameters constituted the variables used for the analysis of conformity to requirements. The primary outcome variable was the conclusion regarding compliance or noncompliance of the inspected local herbal manufacturing facility. GMP parameters that were frequently defaulted by local herbal manufacturers and the corresponding frequencies were identified. The Pearson Chi-square test was applied independently on each category to find the association that existed between conformity and the questions in each category. Only 22% (8) of the 30 inspected facilities were found to comply with GMP requirements, as per National Drug Authority (NDA) guidelines; while the majority of the facilities, 28 (78%), were found not to comply. Of the facilities inspected, 25 were undergoing GMP inspection for the first time. A total of 1,236 deficiency observations were made in the 36 inspection reports reviewed for the study. The mean for all deficiencies was 34.3, and the standard deviation was 15.829. 91.5% of the facilities did not have mechanisms for a record of market complaints; 80.9% did not meet documentation requirements; 78.9% did not have quality control measures in place, and 65.7% did not meet stores requirements. By encouraging a culture of self/voluntary improvement through the introduction of listing of manufacturers based on a maturity level grading, the National Drug Authority will improve the Herbal Medicines sector as per the mandate of improving the herbal medicine industry. Also, increased sensitization of all relevant stakeholders regarding the requirements for GMP should be intensified.
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Agu, Monica, Zita Ekeocha, Stephen Robert Byrn et Kari L. Clase. The Impact of Mentoring as a GMP Capability Building Tool in The Pharmaceutical Manufacturing Industry in Nigeria. Purdue University, décembre 2012. http://dx.doi.org/10.5703/1288284317447.

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Good Manufacturing Practices (GMP), a component of Pharmaceutical Quality Systems, is aimed primarily at managing and minimizing the risks inherent in pharmaceutical manufacture to ensure the quality, safety and efficacy of products. Provision of adequate number of personnel with the necessary qualifications/practical experience and their continuous training and evaluation of effectiveness of the training is the responsibility of the manufacturer. (World Health Organization [WHO], 2014; International Organization for Standardization [ISO], 2015). The classroom method of training that has been used for GMP capacity building in the pharmaceutical manufacturing industry in Nigeria over the years, delivered by experts from stringently regulated markets, have not yielded commensurate improvement in the Quality Management Systems (QMS) in the industry. It is necessary and long over-due to explore an alternative training method that has a track record of success in other sectors. A lot of studies carried out on mentoring as a development tool in several fields such as academia, medicine, business, research etc., reported positive outcomes. The aim of this study was to explore mentoring as an alternative GMP training method in the pharmaceutical manufacturing industry in Nigeria. Specifically, the aim of this study was to evaluate the impact of mentoring as a GMP capability building tool in the pharmaceutical manufacturing industry in Nigeria, with focus on GMP documentations in XYZ pharmaceutical manufacturing company located in South-Western region of Nigeria. The methodology comprised gap assessment of GMP documentation of XYZ company to generate current state data, development of training materials based on the identified gaps and use of the training materials for the mentoring sessions. The outcome of the study was outstanding as gap assessment identified the areas of need that enabled development efforts to be targeted at these areas, unlike generic classroom training. The mentees’ acceptance of the mentoring support was evident by their request for additional training in some other areas related to the microbiology operations that were not covered in the gap assessment. This result portrays mentoring as a promising tool for GMP capacity building, but more structured studies need to be conducted in this area to generate results that can be generalized.
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Sidenkova, Alena, Olga Kremleva, Sergey Bogdanov, Olga Esina et Alena Melnik. Electronic training manual "Psychiatry, medical psychology". SIB-Expertise, janvier 2024. http://dx.doi.org/10.12731/er0786.29012024.

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The electronic training course ""Psychiatry, Medical Psychology"" was compiled in accordance with the requirements of the Federal State Educational Standard of Higher Education, specialty 31.05.01 General Medicine, approved by order of the Ministry of Education and Science of the Russian Federation dated February 9, 2016 No. 95, and taking into account the requirements of the professional standard 02.009 “Physician (precinct general practitioner)”, approved by order of the Ministry of Labor and Social Protection of the Russian Federation dated March 21, 2017 No. 293n, as well as in accordance with the requirements of the Federal State Educational Standard of Higher Education in the specialty 31.05.02 Pediatrics (specialty level), approved by order of the Ministry of Education and Science of the Russian Federation dated 08/17/2015 No. 853, and taking into account the requirements of professional standard 02.008 “Physician - district pediatrician”, approved by order of the Ministry of Labor and Social Protection of the Russian Federation dated 03/27/2017 No. 306n. This course includes issues of private psychiatry and narcology. The purpose of the course is to gain knowledge about the basic patterns of formation and manifestations of mental disorders, their causes, and classification principles. Course objectives: study of classifications of mental disorders; familiarization with the clinical manifestations of mental disorders, their etiological and pathogenetic mechanisms; teaching students the skills to identify symptoms of mental disorders and the skills of describing them in medical documentation. The labor intensity of the course is 45 hours. The course consists of 5 didactic units.
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Lubowa, Nasser, Zita Ekeocha, Stephen Robert Byrn et Kari L. Clase. Pharmaceutical Industry in Uganda : A Review of the Common GMP Non-conformances during Regulatory Inspections. Purdue University, décembre 2021. http://dx.doi.org/10.5703/1288284317442.

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The prevalence of substandard medicines in Africa is high but not well documented. Low and Middle-Income Countries (LMICs) are likely to face considerable challenges with substandard medications. Africa faces inadequate drug regulatory practices, and in general, compliance with Good Manufacturing Practices (GMP) in most of the pharmaceutical industries is lacking. The majority of pharmaceutical manufacturers in developing countries are often overwhelmed by the GMP requirements and therefore are unable to operate in line with internationally acceptable standards. Non-conformances observed during regulatory inspections provide the status of the compliance to GMP requirements. The study aimed to identify the GMP non-conformances during regulatory inspections and gaps in the production of pharmaceuticals locally manufactured in Uganda by review of the available 50 GMP reports of 21 local pharmaceutical companies in Uganda from 2016. The binary logistic generalized estimating equations (GEE) model was applied to estimate the association between odds of a company failing to comply with the GMP requirements and non-conformances under each GMP inspection parameter. Analysis using dummy estimation to linear regression included determination of the relationship that existed between the selected variables (GMP inspection parameters) and the production capacity of the local pharmaceutical industry. Oral liquids, external liquid preparations, powders, creams, and ointments were the main categories of products manufactured locally. The results indicated that 86% of the non-conformances were major, 11% were minor, and 3% critical. The majority of the non-conformances were related to production (30.1%), documentation (24.5%), and quality control (17.6%). Regression results indicated that for every non-conformance under premises, equipment, and utilities, there was a 7-fold likelihood of the manufacturer failing to comply with the GMP standards (aOR=6.81, P=0.001). The results showed that major non-conformances were significantly higher in industries of small scale (B=6.77, P=0.02) and medium scale (B=8.40, P=0.04), as compared to those of large scale. This study highlights the failures in quality assurance systems and stagnated GMP improvements in these industries that need to be addressed by the manufacturers with support from the regulator. The addition of risk assessment to critical production and quality control operations and establishment of appropriate corrective and preventive actions as part of quality management systems are required to ensure that quality pharmaceuticals are manufactured locally.
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Leavy, Michelle B., Danielle Cooke, Sarah Hajjar, Erik Bikelman, Bailey Egan, Diana Clarke, Debbie Gibson, Barbara Casanova et Richard Gliklich. Outcome Measure Harmonization and Data Infrastructure for Patient-Centered Outcomes Research in Depression : Report on Registry Configuration. Agency for Healthcare Research and Quality (AHRQ), novembre 2020. http://dx.doi.org/10.23970/ahrqepcregistryoutcome.

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Background: Major depressive disorder is a common mental disorder. Many pressing questions regarding depression treatment and outcomes exist, and new, efficient research approaches are necessary to address them. The primary objective of this project is to demonstrate the feasibility and value of capturing the harmonized depression outcome measures in the clinical workflow and submitting these data to different registries. Secondary objectives include demonstrating the feasibility of using these data for patient-centered outcomes research and developing a toolkit to support registries interested in sharing data with external researchers. Methods: The harmonized outcome measures for depression were developed through a multi-stakeholder, consensus-based process supported by AHRQ. For this implementation effort, the PRIME Registry, sponsored by the American Board of Family Medicine, and PsychPRO, sponsored by the American Psychiatric Association, each recruited 10 pilot sites from existing registry sites, added the harmonized measures to the registry platform, and submitted the project for institutional review board review Results: The process of preparing each registry to calculate the harmonized measures produced three major findings. First, some clarifications were necessary to make the harmonized definitions operational. Second, some data necessary for the measures are not routinely captured in structured form (e.g., PHQ-9 item 9, adverse events, suicide ideation and behavior, and mortality data). Finally, capture of the PHQ-9 requires operational and technical modifications. The next phase of this project will focus collection of the baseline and follow-up PHQ-9s, as well as other supporting clinical documentation. In parallel to the data collection process, the project team will examine the feasibility of using natural language processing to extract information on PHQ-9 scores, adverse events, and suicidal behaviors from unstructured data. Conclusion: This pilot project represents the first practical implementation of the harmonized outcome measures for depression. Initial results indicate that it is feasible to calculate the measures within the two patient registries, although some challenges were encountered related to the harmonized definition specifications, the availability of the necessary data, and the clinical workflow for collecting the PHQ-9. The ongoing data collection period, combined with an evaluation of the utility of natural language processing for these measures, will produce more information about the practical challenges, value, and burden of using the harmonized measures in the primary care and mental health setting. These findings will be useful to inform future implementations of the harmonized depression outcome measures.
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