Littérature scientifique sur le sujet « Magnetic dual-modal probes »

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Articles de revues sur le sujet "Magnetic dual-modal probes"

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Chen, Bing Di, Tian Zhou, Bo Zhang et Ai Hua Yao. « Novel Single Walled Carbon Nanotube Based Magnetic-Fluorescent Nanohybrids as Dual-Modal MRI/Optical Imaging Probes ». Advanced Materials Research 476-478 (février 2012) : 1134–37. http://dx.doi.org/10.4028/www.scientific.net/amr.476-478.1134.

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Gadolinium chelate and Quantum Dots (QDs) decorated single walled carbon nanotubes (SWNTs) nanohybrids (SWNT-Gd-QDs) were designed for dual-modal cellular imaging via magnetic resonance imaging (MRI) and optical imaging. The nanohybrids were prepared via a simple and novel layer-by-layer (LBL) assembly in combination with covalent connection strategy. The SWNT-Gd-QDs nanohybrids showed a strong near-infrared photoluminescence (PL) emission at room temperature and enhanced T1-weighted and T2-weighted MRI signals in water. Thus, the nanohybrids combine magnetic and fluorescent properties and can serve as dual-modal MRI/optical imaging contrast agent.
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Zhu, Qin, Fei Pan, Yu Tian, Weijun Tang, Yuan Yuan et Aiguo Hu. « Facile synthesis of Gd(iii) metallosurfactant-functionalized carbon nanodots with high relaxivity as bimodal imaging probes ». RSC Advances 6, no 35 (2016) : 29441–47. http://dx.doi.org/10.1039/c6ra02654k.

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Liu, Ping, et Wei Miu. « Hydrothermal synthesis of BaYbF5:Tm3+ nanoparticles for dual-modal upconversion near-infrared luminescence and magnetic resonance imaging ». Functional Materials Letters 09, no 03 (juin 2016) : 1650038. http://dx.doi.org/10.1142/s1793604716500387.

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In this paper, we demonstrate multifunctional upconversion nanoparticles with intense near-infrared emission and unique magnetic properties for dual-modal upconversion luminescent bioimaging and T2-weighted magnetic resonance imaging. High-quality BaYbF5:Tm3+ nanoparticles are synthesized via a hydrophobic method and then converted to be hydrophilic via a hydrochloric acid treatment. The as-synthesized nanoparticles are cubic phase and about 6 nm in diameter with narrow size distribution. The intense near-infrared emission makes these nanoparticles can be acted as bio-probes in upconversion luminescent bioimaging with deep tissue penetration. Besides, these nanoparticles can also be used as T2-weighted contrast agents in magnetic resonance imaging due to the high value of relaxation rate (r2 = 4.05) in 0.55 T. This finding may have further bio-applications in the future due to the high performance of these BaYbF5:Tm3+ nanoparticles in dual-modal bioimaging.
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Stasiuk, Graeme J., Florencia Minuzzi, Myra Sae-Heng, Charlotte Rivas, Hans-Paul Juretschke, Lorenzo Piemonti, Peter R. Allegrini et al. « Dual-Modal Magnetic Resonance/Fluorescent Zinc Probes for Pancreatic β-Cell Mass Imaging ». Chemistry - A European Journal 21, no 13 (3 mars 2015) : 5023–33. http://dx.doi.org/10.1002/chem.201406008.

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Gao, Ai, Dan Zhang et Xue-Bo Yin. « Near infrared fluorescence-magnetic resonance dual-modal imaging with Cy5-labeled, Gd–Al co-doped mesoporous silica nanoparticles ». Analytical Methods 8, no 1 (2016) : 214–21. http://dx.doi.org/10.1039/c5ay02230d.

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We report a reliable and facile procedure to prepare near infrared fluorescence (NIRF)-magnetic resonance dual-modal imaging probes (DMIPs) using Cy5-labeled, Gd–Al co-doped mesoporous silica nanoparticles. High intensity NIRF and a relaxation rate (17.7 mM−1s−1) can be observed. Furthermore, the DMIPs in saline were injected into mice through the tail vein for imaging.
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Fei-Peng, Zhu, Chen Guo-Tao, Wang Shou-Ju, Liu Ying, Tang Yu-Xia, Tian Ying, Wang Jian-Dong et al. « Dual-Modality Imaging Probes with High Magnetic Relaxivity and Near-Infrared Fluorescence Based Highly Aminated Mesoporous Silica Nanoparticles ». Journal of Nanomaterials 2016 (2016) : 1–9. http://dx.doi.org/10.1155/2016/6502127.

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Dual-modal imaging by combining magnetic resonance (MR) and near-infrared (NIR) fluorescence can integrate the advantages of high-resolution anatomical imaging with high sensitivity in vivo fluorescent imaging, which is expected to play a significant role in biomedical researches. Here we report a dual-modality imaging probe (NIR/MR-MSNs) fabricated by conjugating NIR fluorescent heptamethine dyes (IR-808) and MR contrast agents (Gd-DTPA) within highly aminated mesoporous silica nanoparticles (MSNs-NH2). The dual-modality imaging probes NIR/MR-MSNs possess a size of ca. 120 nm. The NIR/MR-MSNs show not only near-infrared fluorescence imaging property with an emission peak at 794 nm, but also highly MRT1relaxivity of 14.54 mM−1 s−1, which is three times more than Gd-DTPA. In vitro experiment reveals high uptake and retention abilities of the nanoprobes, while cell viability assay demonstrates excellent cytocompatibility of the dual-modality imaging probe. After intratumor injection with the NIR/MR-MSNs, MR imaging shows clear anatomical border of the enhanced tumor region while NIR fluorescence exhibits high sensitive tumor detection ability. These intriguing features suggest that this newly developed dual-modality imaging probes have great potential in biomedical imaging.
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Li, Dongdong, Wenzhi Song, Dezhou Wang, Shengyang Qi, Kaishen Li et Wanzhong Yin. « AIEgens functionalized gadolinium-based aminoclay as dual-modal probes for fluorescence and magnetic resonance imaging ». Inorganic Chemistry Communications 95 (septembre 2018) : 32–35. http://dx.doi.org/10.1016/j.inoche.2018.07.003.

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Li, Kai, Dan Ding, Da Huo, Kan-Yi Pu, Ngo Nguyen Phuong Thao, Yong Hu, Zhi Li et Bin Liu. « Conjugated Polymer Based Nanoparticles as Dual-Modal Probes for Targeted In Vivo Fluorescence and Magnetic Resonance Imaging ». Advanced Functional Materials 22, no 15 (30 avril 2012) : 3107–15. http://dx.doi.org/10.1002/adfm.201102234.

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Liu, Chunyan, Zhenyu Gao, Jianfeng Zeng, Yi Hou, Fang Fang, Yilin Li, Ruirui Qiao et al. « Magnetic/Upconversion Fluorescent NaGdF4:Yb,Er Nanoparticle-Based Dual-Modal Molecular Probes for Imaging Tiny Tumors in Vivo ». ACS Nano 7, no 8 (26 juillet 2013) : 7227–40. http://dx.doi.org/10.1021/nn4030898.

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Baziulyte-Paulaviciene, Dovile, Vitalijus Karabanovas, Marius Stasys, Greta Jarockyte, Vilius Poderys, Simas Sakirzanovas et Ricardas Rotomskis. « Synthesis and functionalization of NaGdF4:Yb,Er@NaGdF4 core–shell nanoparticles for possible application as multimodal contrast agents ». Beilstein Journal of Nanotechnology 8 (1 septembre 2017) : 1815–24. http://dx.doi.org/10.3762/bjnano.8.183.

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Upconverting nanoparticles (UCNPs) are promising, new imaging probes capable of serving as multimodal contrast agents. In this study, monodisperse and ultrasmall core and core–shell UCNPs were synthesized via a thermal decomposition method. Furthermore, it was shown that the epitaxial growth of a NaGdF4 optical inert layer covering the NaGdF4:Yb,Er core effectively minimizes surface quenching due to the spatial isolation of the core from the surroundings. The mean diameter of the synthesized core and core–shell nanoparticles was ≈8 and ≈16 nm, respectively. Hydrophobic UCNPs were converted into hydrophilic ones using a nonionic surfactant Tween 80. The successful coating of the UCNPs by Tween 80 has been confirmed by Fourier transform infrared (FTIR) spectroscopy. Scanning electron microscopy (SEM), powder X-ray diffraction (XRD), photoluminescence (PL) spectra and magnetic resonance (MR) T1 relaxation measurements were used to characterize the size, crystal structure, optical and magnetic properties of the core and core–shell nanoparticles. Moreover, Tween 80-coated core–shell nanoparticles presented enhanced optical and MR signal intensity, good colloidal stability, low cytotoxicity and nonspecific internalization into two different breast cancer cell lines, which indicates that these nanoparticles could be applied as an efficient, dual-modal contrast probe for in vivo bioimaging.
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Thèses sur le sujet "Magnetic dual-modal probes"

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Wang, Gaoji [Verfasser]. « Design, Synthesis and Characterization of Zinc-sensitive or dual-modal Probes for Optical and Magnetic Resonance Imaging / Gaoji Wang ». Tübingen : Universitätsbibliothek Tübingen, 2021. http://d-nb.info/1232725846/34.

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Galiyeva, Perizat. « Doped Ag-In-Zn-S and Ag-In-Ga-Zn-S QDs : synthesis and potential as dual-modality probes for magnetic resonance and fluorescence imaging of cells ». Electronic Thesis or Diss., Université de Lorraine, 2021. http://www.theses.fr/2021LORR0118.

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L’imagerie par fluorescence (IF) et l’imagerie de résonance magnétique (IRM) comptent parmi les outils de diagnostic les plus efficaces. Dans ce contexte, des QDs possédant à la fois des propriétés fluorescentes et magnétiques sont d’un grand intérêt en tant que sondes bimodales. Dans ce travail, des QDs Ag-In-Zn-S (AIZS) et Ag-In-Ga-Zn-S (AIGZS) ont été préparés et dopés afin de développer de nouvelles sondes de sondes bimodales pour l’IF et l’IRM. Des QDs AIZS très fluorescents ont été préparés en milieu organique à l’aide de DDT et d’OAm comme ligands. Les QDs Mn:AIZS possèdent des propriétés paramagnétiques et superparamagnétiques. Les QDs AIZS et Mn:AIZS ont également été transférés en phase aqueuse à l’aide du polymère amphiphile PMAO. Par la suite, des QDs AIZS dopés Mn, Gd ou Fe ont été préparés en milieu. Des études toxicologiques et d’imagerie ont montré une bonne biocompatibilité avec les cellules KB ainsi que le fort potentiel de ces nanocristaux pour l’IF. Dans la dernière partie de ce travail, des QDs AIGZS and Mn:AIGZS QDs ont été préparés via un procédé de décomposition thermique n’utilisant qu’un seul précurseur. Ces QDs possèdent de très bonnes propriétés optiques et magnétiques. Les QDs dopés Mn ont été transférés en phase aqueuse et ont montré un fort potentiel comme agent de contraste pour l’imagerie T1 et T2
Since fluorescence imaging (FI) and magnetic resonance imaging (MRI) are among the most effective diagnostic tools, QDs with fluorescent and magnetic properties are of great interest as dual-modal probes. In this work, undoped and doped Ag-In-Zn-S (AIZS) and Ag-In-Ga-Zn-S (AIGZS) QDs were synthesized and investigated as bimodal probes for FI and MRI. Highly fluorescent AIZS QDs were prepared in organic media using DDT and OAm as capping ligands. Mn:AIZS QDs showed paramagnetic and superparamagnetic properties. AIZS and Mn:AIZS QDs were also transferred into aqueous phase using the amphiphilic PMAO polymer. Further, Mn, Gd or Fe-doped AIZS QDs were prepared in aqueous media, showed low cytotoxicity toward KB cells, and demonstrated potential as fluorescent probes for FI. Finally, AIGZS and Mn:AIGZS QDs, synthesized via a novel single precursor thermal decomposition method, showed high fluorescence and paramagnetic/superparamagnetic properties. Mn-doped aqueous transferred AIGZS QDs increased contrast in both T1-weighted and T2-weighted images with increasing in Mn loading
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