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Articles de revues sur le sujet « LST1 »

Auteur : Grafiati

Publié le 9 mars 2023

Mis à jour le 31 juillet 2025

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1

Roberg, Kevin J., Michelle Crotwell, Peter Espenshade, Ruth Gimeno, and Chris A. Kaiser. "LST1 Is a SEC24 Homologue Used for Selective Export of the Plasma Membrane ATPase from the Endoplasmic Reticulum." Journal of Cell Biology 145, no. 4 (1999): 659–72. http://dx.doi.org/10.1083/jcb.145.4.659.

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In Saccharomyces cerevisiae, vesicles that carry proteins from the ER to the Golgi compartment are encapsulated by COPII coat proteins. We identified mutations in ten genes, designated LST (lethal with sec-thirteen), that were lethal in combination with the COPII mutation sec13-1. LST1 showed synthetic-lethal interactions with the complete set of COPII genes, indicating that LST1 encodes a new COPII function. LST1 codes for a protein similar in sequence to the COPII subunit Sec24p. Like Sec24p, Lst1p is a peripheral ER membrane protein that binds to the COPII subunit Sec23p. Chromosomal deleti

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Cui, Yixian, Smriti Parashar, Muhammad Zahoor, et al. "A COPII subunit acts with an autophagy receptor to target endoplasmic reticulum for degradation." Science 365, no. 6448 (2019): 53–60. http://dx.doi.org/10.1126/science.aau9263.

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The COPII-cargo adaptor complex Lst1-Sec23 selectively sorts proteins into vesicles that bud from the endoplasmic reticulum (ER) and traffic to the Golgi. Improperly folded proteins are prevented from exiting the ER and are degraded. ER-phagy is an autophagic degradation pathway that uses ER-resident receptors. Working in yeast, we found an unexpected role for Lst1-Sec23 in ER-phagy that was independent from its function in secretion. Up-regulation of the stress-inducible ER-phagy receptor Atg40 induced the association of Lst1-Sec23 with Atg40 at distinct ER domains to package ER into autophag

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Wan, Jikang, Min Zhu, and Wei Ding. "Accuracy Evaluation and Parameter Analysis of Land Surface Temperature Inversion Algorithm for Landsat-8 Data." Advances in Meteorology 2021 (September 24, 2021): 1–16. http://dx.doi.org/10.1155/2021/9917145.

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Many researchers have developed a variety of land surface temperature (LST) inversion algorithms based on satellite data. The main LST inversion algorithms include Radiative Transfer Equation (RTE), Single Channel (SC) algorithm, Mono Window (MW) algorithm, and Split Window (SW) algorithm. In this study, nine LST inversion algorithms were designed using Landsat-8 data and meteorological station data to test the inversion efficiency of different algorithms in different seasons and different locations. The results show that the error of various LST inversion algorithms will increase with the ris

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Yau, Anthony C. Y., Jonatan Tuncel, Sabrina Haag, et al. "Conserved 33-kb haplotype in the MHC class III region regulates chronic arthritis." Proceedings of the National Academy of Sciences 113, no. 26 (2016): E3716—E3724. http://dx.doi.org/10.1073/pnas.1600567113.

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Genome-wide association studies have revealed many genetic loci associated with complex autoimmune diseases. In rheumatoid arthritis (RA), the MHC gene HLA-DRB1 is the strongest candidate predicting disease development. It has been suggested that other immune-regulating genes in the MHC contribute to the disease risk, but this contribution has been difficult to show because of the strong linkage disequilibrium within the MHC. We isolated genomic regions in the form of congenic fragments in rats to test whether there are additional susceptibility loci in the MHC. By both congenic mapping in inb

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Schiller, Christian, Maximilian J. E. Nitschké, Alexander Seidl, Elisabeth Kremmer, and Elisabeth H. Weiss. "Rat Monoclonal Antibodies Specific for LST1 Proteins." Hybridoma 28, no. 4 (2009): 281–86. http://dx.doi.org/10.1089/hyb.2009.0021.

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Roberg, Kevin J., Stephen Bickel, Neil Rowley, and Chris A. Kaiser. "Control of Amino Acid Permease Sorting in the Late Secretory Pathway of Saccharomyces cerevisiae by SEC13, LST4, LST7 and LST78." Genetics 147, no. 4 (1997): 1569–84. http://dx.doi.org/10.1093/genetics/147.4.1569.

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Abstract The SEC13 gene was originally identified by temperature-sensitive mutations that block all protein transport from the ER to the Golgi. We have found that at a permissive temperature for growth, the sec13-1 mutation selectively blocks transport of the nitrogen-regulated amino acid permease, Gaplp, from the Golgi to the plasma membrane, but does not affect the activity of constitutive permeases such as Hip1p, Can1p, or Lyp1p. Different alleles of SEC13 exhibit different relative effects on protein transport from the ER to the Golgi, or on Gap1p activity, indicating distinct requirements

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Rollinger-Holzinger, Ingrid, Brigitte Eibl, Marc Pauly, et al. "LST1: A Gene with Extensive Alternative Splicing and Immunomodulatory Function." Journal of Immunology 164, no. 6 (2000): 3169–76. http://dx.doi.org/10.4049/jimmunol.164.6.3169.

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Schiller, Christian, Carina Nowak, Kalliope N. Diakopoulos, Ulrich H. Weidle, and Elisabeth H. Weiss. "An Upstream Open Reading Frame Regulates LST1 Expression during Monocyte Differentiation." PLoS ONE 9, no. 5 (2014): e96245. http://dx.doi.org/10.1371/journal.pone.0096245.

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Weidle, Ulrich H., Ina Rohwedder, Fabian Birzele, Elisabeth H. Weiss, and Christian Schiller. "LST1: A multifunctional gene encoded in the MHC class III region." Immunobiology 223, no. 11 (2018): 699–708. http://dx.doi.org/10.1016/j.imbio.2018.07.018.

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D’Aloia, Alessia, Edoardo Arrigoni, Barbara Costa, et al. "RalGPS2 Interacts with Akt and PDK1 Promoting Tunneling Nanotubes Formation in Bladder Cancer and Kidney Cells Microenvironment." Cancers 13, no. 24 (2021): 6330. http://dx.doi.org/10.3390/cancers13246330.

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RalGPS2 is a Ras-independent Guanine Nucleotide Exchange Factor for RalA GTPase that is involved in several cellular processes, including cytoskeletal organization. Previously, we demonstrated that RalGPS2 also plays a role in the formation of tunneling nanotubes (TNTs) in bladder cancer 5637 cells. In particular, TNTs are a novel mechanism of cell–cell communication in the tumor microenvironment, playing a central role in cancer progression and metastasis formation. However, the molecular mechanisms involved in TNTs formation still need to be fully elucidated. Here we demonstrate that mid and

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Woo, Jeyoung, and Chaeyoung Lee. "Identification of Functional Haplotypes in the Promoter Region of the LST1 Gene." Biochemical Genetics 52, no. 7-8 (2014): 365–71. http://dx.doi.org/10.1007/s10528-014-9653-x.

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Shimoni, Yuval, Tatsuo Kurihara, Mariella Ravazzola, Mylène Amherdt, Lelio Orci, and Randy Schekman. "Lst1p and Sec24p Cooperate in Sorting of the Plasma Membrane Atpase into Copii Vesicles in Saccharomyces cerevisiae." Journal of Cell Biology 151, no. 5 (2000): 973–84. http://dx.doi.org/10.1083/jcb.151.5.973.

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Formation of ER-derived protein transport vesicles requires three cytosolic components, a small GTPase, Sar1p, and two heterodimeric complexes, Sec23/24p and Sec13/31p, which comprise the COPII coat. We investigated the role of Lst1p, a Sec24p homologue, in cargo recruitment into COPII vesicles in Saccharomyces cerevisiae. A tagged version of Lst1p was purified and eluted as a heterodimer complexed with Sec23p comparable to the Sec23/24p heterodimer. We found that cytosol from an lst1-null strain supported the packaging of α-factor precursor into COPII vesicles but was deficient in the packagi

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Schiller, C., K. N. Diakopoulos, I. Rohwedder, et al. "LST1 promotes the assembly of a molecular machinery responsible for tunneling nanotube formation." Journal of Cell Science 126, no. 3 (2012): 767–77. http://dx.doi.org/10.1242/jcs.114033.

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Lumi, Xhevat, Mateja M. Jelen, Daša Jevšinek Skok, et al. "Comparison of SNP Genotypes Related to Proliferative Vitreoretinopathy (PVR) across Slovenian and European Subpopulations." Journal of Ophthalmology 2018 (2018): 1–7. http://dx.doi.org/10.1155/2018/8761625.

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The present study investigated the distribution of genotypes within single nucleotide polymorphisms (SNPs) in genes, related to PVR pathogenesis across European subpopulations. Genotype distributions of 42 SNPs among 96 Slovenian healthy controls were investigated and compared to genotype frequencies in 503 European individuals (Ensembl database) and their subpopulations. Furthermore, a case-control status was simulated to evaluate effects of allele frequency changes on statistically significant results in gene-association studies investigating functional polymorphisms. In addition, 96 healthy

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de Baey, A., B. Fellerhoff, S. Maier, and E. H. Weiss. "Tissue specific expression and alternative splicing of the LST1 gene of the TNF region." Human Immunology 47, no. 1-2 (1996): 65. http://dx.doi.org/10.1016/0198-8859(96)85042-7.

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Holzinger, Ingrid, Annegret de Baey, Gerald Messer, Gerold Kick, Heinz Zwierzina, and Elizabeth H. Weiss. "Cloning and genomic characterization of LST1: a new gene in the human TNF region." Immunogenetics 42, no. 5 (1995): 315–22. http://dx.doi.org/10.1007/bf00179392.

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Qin, Wentao, Fu Gan, Riguan Liang, et al. "Identification of Monocyte-Associated Genes Related to the Instability of Atherosclerosis Plaque." Oxidative Medicine and Cellular Longevity 2022 (September 21, 2022): 1–21. http://dx.doi.org/10.1155/2022/3972272.

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Background. Atherosclerotic plaque instability is a common cause of stroke and ischemic infarction, and identification of monocyte-associated genes has become a prominent feature in cardiovascular research as a contributing/predictive marker. Methods. Whole genome sequencing data were downloaded from GSE159677, GSE41571, GSE120521, and GSE118481. Single-cell sequencing data analysis was conducted to cluster molecular subtypes of atherosclerotic plaques and identify specific genes. Differentially expressed genes (DEGs) between normal subjects and patients with unstable atheromatous plaques were

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Ovsyannikova, Inna G., Robert A. Vierkant, V. Shane Pankratz, Robert M. Jacobson, and Gregory A. Poland. "Extended LTA, TNF, LST1 and HLA Gene Haplotypes and Their Association with Rubella Vaccine-Induced Immunity." PLoS ONE 5, no. 7 (2010): e11806. http://dx.doi.org/10.1371/journal.pone.0011806.

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de Baey, Annegret, Barbara Fellerhoff, Sabine Maier, Silvia Martinozzi, Ullrich Weidle, and Elisabeth H. Weiss. "Complex Expression Pattern of the TNF Region Gene LST1 through Differential Regulation, Initiation, and Alternative Splicing." Genomics 45, no. 3 (1997): 591–600. http://dx.doi.org/10.1006/geno.1997.4963.

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Lei, Haixin, and Igor Vořechovský. "Identification of Splicing Silencers and Enhancers in Sense Alus: a Role for Pseudoacceptors in Splice Site Repression." Molecular and Cellular Biology 25, no. 16 (2005): 6912–20. http://dx.doi.org/10.1128/mcb.25.16.6912-6920.2005.

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ABSTRACT Auxiliary splicing signals in introns play an important role in splice site selection, but these elements are poorly understood. We show that a subset of serine/arginine (SR)-rich proteins activate a cryptic 3′ splice site in a sense Alu repeat located in intron 4 of the human LST1 gene. Utilization of this cryptic splice site is controlled by juxtaposed Alu-derived splicing silencers and enhancers between closely linked short tandem repeats TNFd and TNFe. Systematic mutagenesis of these elements showed that AG dinucleotides that were not preceded by purine residues were critical for

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Liu, Guiyou, Yang Hu, Shuilin Jin, Fang Zhang, Qinghua Jiang, and Junwei Hao. "Cis-eQTLs regulate reduced LST1 gene and NCR3 gene expression and contribute to increased autoimmune disease risk." Proceedings of the National Academy of Sciences 113, no. 42 (2016): E6321—E6322. http://dx.doi.org/10.1073/pnas.1614369113.

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Mulcahy, H., K. P. O'Rourke, C. Adams, M. G. Molloy та F. O'Gara. "LST1 and NCR3 expression in autoimmune inflammation and in response to IFN-γ, LPS and microbial infection". Immunogenetics 57, № 12 (2005): 893–903. http://dx.doi.org/10.1007/s00251-005-0057-2.

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Janus, G., T. Samson, R. Faudon, C. Renaudeau, M. Joussemet, and G. Fabre. "Conséquences sur les PSL de la déleucocytation par filtration du sang total avec le filtre intégré Leucoflex® LST1." Transfusion Clinique et Biologique 4, no. 6 (1997): 549–57. http://dx.doi.org/10.1016/s1246-7820(97)80080-8.

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Woollacott, Christine, and Quentin C. B. Cronk. "The hooded mutant of Lathyrus odoratus (Fabaceae) is associated with a cycloidea gene mutation." Botany 96, no. 1 (2018): 47–55. http://dx.doi.org/10.1139/cjb-2017-0097.

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The hooded (hdd) floral mutant of Lathyrus odoratus L. (sweet pea) has a concave standard petal compared with the flat standard petal of the wild type. This trait was used by Bateson, Punnett, and Saunders in early studies of Mendelian inheritance (c.1905). Here we provide four lines of evidence that this phenotype results from a mutation in the CYCLOIDEA2 (CYC2) gene. (i) CYC2 is expressed in the standard petals of wild-type L. odoratus, whereas the same methods fail to detect expression in hdd plants. (ii) Genomic sequencing reveals that the CYC2 gene sequence of hdd plants is truncated at t

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Raghunathan, Arumugham, Ramou Sivakamasundari, Joseph Wolenski, Ranjana Poddar, and Sherman M. Weissman. "Functional Analysis of B144/LST1: A Gene in the Tumor Necrosis Factor Cluster That Induces Formation of Long Filopodia in Eukaryotic Cells." Experimental Cell Research 268, no. 2 (2001): 230–44. http://dx.doi.org/10.1006/excr.2001.5290.

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Chu, Francesco, Fausto Maffini, Daniela Lepanto, et al. "The Genetic and Immunologic Landscape Underlying the Risk of Malignant Progression in Laryngeal Dysplasia." Cancers 15, no. 4 (2023): 1117. http://dx.doi.org/10.3390/cancers15041117.

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(1) Background: The development of laryngeal cancer is a multistep process involving structural alterations of the epithelial mucosa, from dysplasia (LDy) to invasive carcinoma. In this study, we define new biomarkers, prognostic for malignant transformation, in patients affected by LDy. (2) Methods: We used targeted next-generation sequencing and immunohistochemical analysis to define the mutational and immunological landscape of 15 laryngeal dysplasia progressing to invasive cancer (progressing dysplasia), as well as 31 cases of laryngeal dysplasia that did not progress to carcinoma (non-pro

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Draber, Peter, Ondrej Stepanek, Matous Hrdinka, et al. "LST1/A Is a Myeloid Leukocyte-specific Transmembrane Adaptor Protein Recruiting Protein Tyrosine Phosphatases SHP-1 and SHP-2 to the Plasma Membrane." Journal of Biological Chemistry 287, no. 27 (2012): 22812–21. http://dx.doi.org/10.1074/jbc.m112.339143.

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Draber, Peter, Ondrej Stepanek, Matous Hrdinka, et al. "LST1/A is a myeloid leukocyte-specific transmembrane adaptor protein recruiting protein tyrosine phosphatases SHP-1 and SHP-2 to the plasma membrane." Journal of Biological Chemistry 288, no. 39 (2013): 28309. http://dx.doi.org/10.1074/jbc.a112.339143.

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Nagy, Gyula Richárd, Balázs Gyõrffy, Orsolya Galamb, Béla Molnár, Bálint Nagy, and Zoltán Papp. "Use of Routinely Collected Amniotic Fluid for Whole-Genome Expression Analysis of Polygenic Disorders." Clinical Chemistry 52, no. 11 (2006): 2013–20. http://dx.doi.org/10.1373/clinchem.2006.074971.

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Abstract Background: Neural tube defects related to polygenic disorders are the second most common birth defects in the world, but no molecular biologic tests are available to analyze the genes involved in the pathomechanism of these disorders. We explored the use of routinely collected amniotic fluid to characterize the differential gene expression profiles of polygenic disorders. Methods: We used oligonucleotide microarrays to analyze amniotic fluid samples obtained from pregnant women carrying fetuses with neural tube defects diagnosed during ultrasound examination. The control samples were

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Pacitto, Angela, David B. Ascher, Louise H. Wong, et al. "Lst4, the yeast Fnip1/2 orthologue, is a DENN-family protein." Open Biology 5, no. 12 (2015): 150174. http://dx.doi.org/10.1098/rsob.150174.

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The folliculin/Fnip complex has been demonstrated to play a crucial role in the mechanisms underlying Birt–Hogg–Dubé (BHD) syndrome, a rare inherited cancer syndrome. Lst4 has been previously proposed to be the Fnip1/2 orthologue in yeast and therefore a member of the DENN family. In order to confirm this, we solved the crystal structure of the N-terminal region of Lst4 from Kluyveromyces lactis and show it contains a longin domain, the first domain of the full DENN module. Furthermore, we demonstrate that Lst4 through its DENN domain interacts with Lst7, the yeast folliculin orthologue. Like

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Geng, Huimin, Donna Neuberg, Elisabeth Paietta, et al. "Integrative Genome-Wide DNA Methylation and Gene Expression Analysis Reveals Biological and Clinical Insights In Adult Acute Lymphoblastic Leukemia." Blood 116, no. 21 (2010): 852. http://dx.doi.org/10.1182/blood.v116.21.852.852.

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Abstract Abstract 852 Adult acute lymphoblastic leukemia (ALL) is an aggressive disease with <30% long-term survival. This relatively poor outcome can be explained in part by an increased frequency of high-risk molecular subtypes compared to childhood ALL, such as BCR/ABL (20%-40% in adults vs 2%-5% in children). We hypothesized that aberrant epigenetic gene regulation contributes to the pathogenesis and clinical features of adult ALL. We therefore performed genome-wide DNA methylation and gene expression microarray studies of 215 adult patients with B-lineage ALL enrolled in the ECOG E2993

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Meng, Jiaqi, Chengbo Li, Jin Tao, et al. "RNN-LSTM-Based Model Predictive Control for a Corn-to-Sugar Process." Processes 11, no. 4 (2023): 1080. http://dx.doi.org/10.3390/pr11041080.

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The corn-to-sugar process is difficult to control automatically because of the complex physical and chemical phenomena involved. Because the RNN-LSTN model has been shown to handle long-term time dependencies well, this article focused on the design of a model predictive control system based on this machine learning model. Based on the historical data, we first reduced the input variable dimension through data preprocessing, data dimension reduction, sensitivity analysis, etc., and then the RNN-LSTM model, with these identified key sites as inputs, and the dextrose equivalent value as the outp

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Zhang, Jiaqi, Xiangjin Shen, Yanji Wang, Ming Jiang, and Xianguo Lu. "Effects of Forest Changes on Summer Surface Temperature in Changbai Mountain, China." Forests 12, no. 11 (2021): 1551. http://dx.doi.org/10.3390/f12111551.

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The area and vegetation coverage of forests in Changbai Mountain of China have changed significantly during the past decades. Understanding the effects of forests and forest coverage change on regional climate is important for predicting climate change in Changbai Mountain. Based on the satellite-derived land surface temperature (LST), albedo, evapotranspiration, leaf area index, and land-use data, this study analyzed the influences of forests and forest coverage changes on summer LST in Changbai Mountain. Results showed that the area and vegetation coverage of forests increased in Changbai Mo

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Veraverbeke, Sander, Willem W. Verstraeten, Stefaan Lhermitte, Ruben Van De Kerchove, and Rudi Goossens. "Assessment of post-fire changes in land surface temperature and surface albedo, and their relation with fire - burn severity using multitemporal MODIS imagery." International Journal of Wildland Fire 21, no. 3 (2012): 243. http://dx.doi.org/10.1071/wf10075.

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This study evaluates the effects of the large 2007 Peloponnese (Greece) wildfires on changes in broadband surface albedo (α), daytime land surface temperature (LSTd) and night-time LST (LSTn) using a 2-year post-fire time series of Moderate Resolution Imaging Spectroradiometer satellite data. In addition, it assesses the potential of remotely sensed α and LST as indicators for fire–burn severity. Immediately after the fire event, mean α dropped up to 0.039 (standard deviation = 0.012) (P < 0.001), mean LSTd increased up to 8.4 (3.0) K (P < 0.001), and mean LSTn decreased up to –1.2 (1.5)

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Wejryd, Erik, Erik Freiholtz Jern, Giovanna Marchini, Ulrika Åden, Eva Landberg, and Thomas Abrahamsson. "Human Milk Oligosaccharides in Breast Milk at Two Weeks of Age in Relation to Neurodevelopment in 2-Year-Old Children Born Extremely Preterm: An Explorative Trial." Nutrients 17, no. 5 (2025): 832. https://doi.org/10.3390/nu17050832.

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Background: Preventing neurodevelopmental impairment after extremely preterm birth remains challenging. While breast milk feeding is linked to better neurodevelopment, the underlying mechanisms are unclear. This study explored the association between individual human milk oligosaccharides (HMO) and neurodevelopment at two years of age in extremely preterm children. Methods: Milk samples from mothers of 76 extremely preterm infants collected at two weeks after birth were analyzed for 15 dominant HMOs. Register data from examination and Bayley-III neurodevelopmental assessment at two years’ corr

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Sayyad, Sameer, Satish Kumar, Arunkumar Bongale, Ketan Kotecha, and Ajith Abraham. "Remaining Useful-Life Prediction of the Milling Cutting Tool Using Time–Frequency-Based Features and Deep Learning Models." Sensors 23, no. 12 (2023): 5659. http://dx.doi.org/10.3390/s23125659.

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The milling machine serves an important role in manufacturing because of its versatility in machining. The cutting tool is a critical component of machining because it is responsible for machining accuracy and surface finishing, impacting industrial productivity. Monitoring the cutting tool’s life is essential to avoid machining downtime caused due to tool wear. To prevent the unplanned downtime of the machine and to utilize the maximum life of the cutting tool, the accurate prediction of the remaining useful life (RUL) cutting tool is essential. Different artificial intelligence (AI) techniqu

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Péli-Gulli, Marie-Pierre, Alessandro Sardu, Nicolas Panchaud, Serena Raucci, and Claudio De Virgilio. "Amino Acids Stimulate TORC1 through Lst4-Lst7, a GTPase-Activating Protein Complex for the Rag Family GTPase Gtr2." Cell Reports 13, no. 1 (2015): 1–7. http://dx.doi.org/10.1016/j.celrep.2015.08.059.

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Péli-Gulli, Marie-Pierre, Serena Raucci, Zehan Hu, Jörn Dengjel, and Claudio De Virgilio. "Feedback Inhibition of the Rag GTPase GAP Complex Lst4-Lst7 Safeguards TORC1 from Hyperactivation by Amino Acid Signals." Cell Reports 20, no. 2 (2017): 281–88. http://dx.doi.org/10.1016/j.celrep.2017.06.058.

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Nahyan, Al Mahmud, and Amjad Munni Shahfida. "Qualitative Analysis of PLP in LSTM for Bangla Speech Recognition." International Journal of Multimedia & Its Applications (IJMA) 12, no. 5 (2022): 1–8. https://doi.org/10.5281/zenodo.7229505.

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The performance of various acoustic feature extraction methods has been compared in this work using Long Short-Term Memory (LSTM) neural network in a Bangla speech recognition system. The acoustic features are a series of vectors that represents the speech signals. They can be classified in either words or sub word units such as phonemes. In this work, at first linear predictive coding (LPC) is used as acoustic vector extraction technique. LPC has been chosen due to its widespread popularity. Then other vector extraction techniques like Mel frequency cepstral coefficients (MFCC) and perceptual

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Murugesan, R., Eva Mishra, and Akash Hari Krishnan. "Forecasting agricultural commodities prices using deep learning-based models: basic LSTM, bi-LSTM, stacked LSTM, CNN LSTM, and convolutional LSTM." International Journal of Sustainable Agricultural Management and Informatics 8, no. 3 (2022): 242. http://dx.doi.org/10.1504/ijsami.2022.125757.

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Krishnan, Akash Hari, R. Murugesan, and Eva Mishra. "Forecasting agricultural commodities prices using deep learning-based models: basic LSTM, bi-LSTM, stacked LSTM, CNN LSTM, and convolutional LSTM." International Journal of Sustainable Agricultural Management and Informatics 8, no. 3 (2022): 1. http://dx.doi.org/10.1504/ijsami.2022.10048228.

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Van Epps, Heather L. "LSP1." Journal of Experimental Medicine 201, no. 3 (2005): 319. http://dx.doi.org/10.1084/jem2013iti4.

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Andriyanov, Nikita A., David A. Petrosov, and Andrey V. Polyakov. "SELECTING AN ARTIFICIAL NEURAL NETWORK ARCHITECTURE FOR ASSESSING THE STATE OF A GENETIC ALGORITHM POPULATION IN THE PROBLEM OF STRUCTURAL-PARAMETRIC SYNTHESIS OF SIMULATION MODELS OF BUSINESS PROCESSES." SOFT MEASUREMENTS AND COMPUTING 12, no. 73 (2023): 70–81. http://dx.doi.org/10.36871/2618-9976.2023.12.007.

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This article proposes a study aimed at determining the architecture of artificial neural networks to solve the problem of determining the population state of a genetic algorithm adapted to solve the problem of structuralparametric synthesis of simulation models of business processes. As the initial data for training the artificial neural network, we used the results of computational experiments obtained when operating a genetic algorithm model based on mathematical nested Petri nets, which solves the problem of synthesizing business process models (Petri net models) based on a given behavior.

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Lin, Ting-Hui, Xueyong Zhu, Shengyang Wang, et al. "A single mutation in bovine influenza H5N1 hemagglutinin switches specificity to human receptors." Science 386, no. 6726 (2024): 1128–34. https://doi.org/10.1126/science.adt0180.

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In 2024, several human infections with highly pathogenic clade 2.3.4.4b bovine influenza H5N1 viruses in the United States raised concerns about their capability for bovine-to-human or even human-to-human transmission. In this study, analysis of the hemagglutinin (HA) from the first-reported human-infecting bovine H5N1 virus (A/Texas/37/2024, Texas) revealed avian-type receptor binding preference. Notably, a Gln 226 Leu substitution switched Texas HA binding specificity to human-type receptors, which was enhanced when combined with an Asn 224 Lys mutation. Crystal structures of the Texas HA wi

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Deb, Gauri, Bettina Wingelhofer, Emma Williams, Hui-Sun Leong, and Tim CP Somervaille. "Genome-Wide CRISPR-Cas9 Screen Identifies Sensitizers to LSD1 Inhibition in MLL-Translocated Human AML Cells." Blood 132, Supplement 1 (2018): 178. http://dx.doi.org/10.1182/blood-2018-178.

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Abstract Lysine-specific demethylase (LSD1, also known as KDM1A) is an epigenetic regulator that has recently emerged as a potential therapeutic target in acute myeloid leukemia (AML). It is a flavin dependent monoamine oxidase which can demethylate monomethyl or dimethyl lysine 4 of histone H3. Pharmacological inhibition of LSD1 induces differentiation of blast cells in MLL-translocated AML and has shown significant promise in pre-clinical studies. With LSD1 inhibitors advancing through early-phase clinical trials, there is a strong pre-clinical rationale for the identification of genes whose

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Chawngthu, Zoremsanga, and Hussain Jamal. "An Evaluation of Bidirectional Long Short-Term Memory Model for Estimating Monthly Rainfall in India." Indian Journal of Science and Technology 17, no. 18 (2024): 1828–37. https://doi.org/10.17485/IJST/v17i18.2505.

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Abstract <strong>Objectives:</strong> Predicting the amount of rainfall is difficult due to its complexity and non-linearity. The objective of this study is to predict the average rainfall one month ahead using the all-India monthly average rainfall dataset from 1871 to 2016. <strong>Methods:</strong> This study proposed a Bidirectional Long Short-Term Memory (LSTM) model to predict the average monthly rainfall in India. The parameters of the models are determined using the grid search method. This study utilized the average monthly rainfall as an input, and the dataset consists

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Atitar, Mariam, and JosÉ Antonio Sobrino. "A Split-Window Algorithm for Estimating LST From Meteosat 9 Data: Test and Comparison With Data and MODIS LSTs." IEEE Geoscience and Remote Sensing Letters 6, no. 1 (2009): 122–26. http://dx.doi.org/10.1109/lgrs.2008.2006410.

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Victor, Nancy, and Daphne Lopez. "sl-LSTM." International Journal of Grid and High Performance Computing 12, no. 3 (2020): 1–16. http://dx.doi.org/10.4018/ijghpc.2020070101.

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The volume of data in diverse data formats from various data sources has led the way for a new drift in the digital world, Big Data. This article proposes sl-LSTM (sequence labelling LSTM), a neural network architecture that combines the effectiveness of typical LSTM models to perform sequence labeling tasks. This is a bi-directional LSTM which uses stochastic gradient descent optimization and combines two features of the existing LSTM variants: coupled input-forget gates for reducing the computational complexity and peephole connections that allow all gates to inspect the current cell state.

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Liu, Zhandong, Wengang Zhou, and Houqiang Li. "AB-LSTM." ACM Transactions on Multimedia Computing, Communications, and Applications 15, no. 4 (2020): 1–23. http://dx.doi.org/10.1145/3356728.

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Moon, Jihoon, Yuna Han, Hangbae Chang, and Seungmin Rho. "Multistep-Ahead Solar Irradiance Forecasting for Smart Cities Based on LSTM, Bi-LSTM, and GRU Neural Networks." Journal of Society for e-Business Studies 27, no. 4 (2022): 27–52. http://dx.doi.org/10.7838/jsebs.2022.27.4.027.

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