Littérature scientifique sur le sujet « Intraclonal »
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Articles de revues sur le sujet "Intraclonal"
Gurrieri, Carmela, Peter McGuire, Hong Zan, Xiao-Jie Yan, Andrea Cerutti, Emilia Albesiano, Steven L. Allen et al. « Chronic Lymphocytic Leukemia B Cells Can Undergo Somatic Hypermutation and Intraclonal Immunoglobulin VHDJH Gene Diversification ». Journal of Experimental Medicine 196, no 5 (2 septembre 2002) : 629–39. http://dx.doi.org/10.1084/jem.20011693.
Texte intégralVolkheimer, Alicia D., J. Brice Weinberg, Bethany E. Beasley, John F. Whitesides, Jon P. Gockerman, Joseph O. Moore, Garnett Kelsoe, Barbara K. Goodman et Marc C. Levesque. « Progressive immunoglobulin gene mutations in chronic lymphocytic leukemia : evidence for antigen-driven intraclonal diversification ». Blood 109, no 4 (2 novembre 2006) : 1559–67. http://dx.doi.org/10.1182/blood-2006-05-020644.
Texte intégralRawstron, Andy C., James A. L. Fenton, Marieth Plummer, Harry O. King, Fiona L. Bennett, Andrew S. Jack et Peter Hillmen. « Monoclonal B-Cell Lymphocytosis (MBL) and CLL Show Intraclonal Variation : Cases Classified as “Unmutated” Have the Greatest Clonal Diversity. » Blood 108, no 11 (16 novembre 2006) : 30. http://dx.doi.org/10.1182/blood.v108.11.30.30.
Texte intégralRajamanickam, C., et K. Rajmohan. « Intraclonal Variation in Musa (AAB) Palayankodan ». International Journal of Current Microbiology and Applied Sciences 9, no 6 (10 juin 2020) : 269–75. http://dx.doi.org/10.20546/ijcmas.2020.906.034.
Texte intégralZojer, Niklas, Heinz Ludwig, Michael Fiegl, Freda K. Stevenson et Surinder S. Sahota. « Patterns of somatic mutations in VH genes reveal pathways of clonal transformation from MGUS to multiple myeloma ». Blood 101, no 10 (15 mai 2003) : 4137–39. http://dx.doi.org/10.1182/blood-2002-09-2825.
Texte intégralBartholdy, Boris A., Xiahoua Wang, Xiao-Jie Yan, Marién Pascual, Manxia Fan, Jacqueline Barrientos, Steven L. Allen et al. « CLL intraclonal fractions exhibit established and recently acquired patterns of DNA methylation ». Blood Advances 4, no 5 (9 mars 2020) : 893–905. http://dx.doi.org/10.1182/bloodadvances.2019000817.
Texte intégralHale, Anna L., J. Creighton Miller, K. Renganayaki, Alan K. Fritz, J. J. Coombs, L. M. Frank et D. S. Douches. « Suitability of AFLP and Microsatellite Marker Analysis for Discriminating Intraclonal Variants of the Potato Cultivar Russet Norkotah ». Journal of the American Society for Horticultural Science 130, no 4 (juillet 2005) : 624–30. http://dx.doi.org/10.21273/jashs.130.4.624.
Texte intégralBeke, Allan, Lucie Laplane, Julie Riviere, Qin Yang, Miguel Torres-Martin, Thibault Dayris, Philippe Rameau et al. « Multilayer intraclonal heterogeneity in chronic myelomonocytic leukemia ». Haematologica 105, no 1 (2 mai 2019) : 112–23. http://dx.doi.org/10.3324/haematol.2018.208488.
Texte intégralAarts, Wilhelmina M., Richard J. Bende, Eric J. Steenbergen, Philip M. Kluin, Engelbert C. M. Ooms, Steven T. Pals et Carel J. M. van Noesel. « Variable heavy chain gene analysis of follicular lymphomas : correlation between heavy chain isotype expression and somatic mutation load ». Blood 95, no 9 (1 mai 2000) : 2922–29. http://dx.doi.org/10.1182/blood.v95.9.2922.009k38_2922_2929.
Texte intégralFagerström, T., et A. G. B. Poore. « Intraclonal Variation in Macroalgae : Causes and Evolutionary Consequences ». Selection 1, no 1-3 (janvier 2001) : 123–34. http://dx.doi.org/10.1556/select.1.2000.1-3.12.
Texte intégralThèses sur le sujet "Intraclonal"
Marie, Joan. « Intraclonal Morphological Plasticity within the Myzus persicae (Sulzer) Complex Related to Host Plant and Temperature ». Thesis, Virginia Tech, 2004. http://hdl.handle.net/10919/33305.
Texte intégralMaster of Science
Martin, Patricia. « La génération d'un polymorphisme génétique intraclonal est modulée pendant la différenciation chez Streptomyces ambofaciens ATCC23877 ». Nancy 1, 2000. http://www.theses.fr/2000NAN10110.
Texte intégralBrioli, Annamaria <1982>. « The impact of intraclonal heterogeneity on the outcomes of Multiple Myeloma patients treated with new drugs ». Doctoral thesis, Alma Mater Studiorum - Università di Bologna, 2015. http://amsdottorato.unibo.it/6779/1/Brioli_Annamaria_tesi.pdf.
Texte intégralBrioli, Annamaria <1982>. « The impact of intraclonal heterogeneity on the outcomes of Multiple Myeloma patients treated with new drugs ». Doctoral thesis, Alma Mater Studiorum - Università di Bologna, 2015. http://amsdottorato.unibo.it/6779/.
Texte intégralSutton, Lesley Ann. « Molecular and Genetic Evidence for Antigen Selection in the Pathogenesis of Chronic Lymphocytic Leukemia ». Doctoral thesis, Uppsala universitet, Hematologi och immunologi, 2012. http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-181602.
Texte intégralVorwerk, Sonja. « Molecular evidence of intraclonal variation and implications for adaptational traits of grape phylloxera populations (Daktulosphaira vitifoliae, Fitch) ». [S.l. : s.n.], 2007. http://nbn-resolving.de/urn:nbn:de:bsz:100-opus-2086.
Texte intégralJacobs, Claudia. « Untersuchung entfernt lokalisierter Gewebeproben kutaner B-Zell-Lymphome auf intraklonale Diversität mit der Einzel-Zell-PCR-Technik ». Doctoral thesis, Humboldt-Universität zu Berlin, Medizinische Fakultät - Universitätsklinikum Charité, 2000. http://dx.doi.org/10.18452/14571.
Texte intégralabstract The molecularbiological investigation of the immunoglobulin variable region genes of two patients suffering on primary cutaneous B-cell-lymphoma was carried out using single-cell- PCR technic. The main focus lay on the aspect on the aspect of detecting intraclonal diversity. The sequence nucleotid-analysises of the immunoglubulin light chain genes obtained from a total of 100 investigated tumor B-cells in patient WS revealed intraclonal diversity among cells isolated from three spatially separated tissue samples. Considering the mutational pattern and the subclones in dependence on the tumorcells, taken from different topographical tumorsides, an antigen-driven clonal expansion could be supposed. Despite extensive efforts and the analysis of altogether 126 tumor B-cells out of eight spatially different localised biopsies, no intraclonal diversity could be observed for the immunoglobulin heavy chain rearrangement of second patient LB. Sequence differences of the Ig light chain based on only a single silent mutation within the CDR1 region. This mutation has no functional affect of the amino acid sequence and therefore little prognostical significance. In both cases the immunoglobulin genes were somatically hypermutated in compromise to the germ-line gene. From the molecularbiological point of view, the tumor cells of patient WS descended from germinal center cells, whereas the tumor B-cells of patient LB rather can be characterized as post-germinal center cells. The results clearly demonstrate, that the investigation of a single tissue sample of primary cutaneous B-cell lymphoma using micromanipulation and single cell-PCR technic may not be representative for the whole tumor. Publications concluding monoclonality with no intraclonal diversity from the analysis of a single biopsie therefore have to be interpreted with caution (74;76;77;84). Accordingly, an appropiate molecularbiological characterization of tumor B-cells regarding their developmental stage and origin has to consider spatial and time dependant aspects. Only the investigation of sequential biopsies may reliably detect ongoing mutations in tumor B-cells. The combination of micromanipulation and single cell PCR represents an elegant method to observe intraclonal diversity. The technic will give contribution to molecularbiological investigation of the pathogenesis of primary cutaneous B-cell lymphomas. It could be of interest to apply this method to the evaluation of current therapies with respect to its capability to eradicating the malignant cell clone completely, and to draw conclusions on disease progression and prognosis.
Koyo, Jean-Prosper. « Bouturage et variabilité morphogénétique de clones de Terminalia superba Engler et Diels ou Limba du Sud-Congo ». Paris 11, 1985. http://www.theses.fr/1985PA112011.
Texte intégralAsexual propagation and morphogenetic clonal variability of Terminalia superba Engler and Diels (Limba) in South Congo. Genetic improvement of Terminalia superba by asexual propagation has been studied in Congo as part of an industrial reforestation project. One hundred elite Limba, selected in South Congo forests, were cloned and since 1976 have been studied in several trials. A technique of establishing cuttings is now well understood and the growth of clones is encouraging, but rejuvenation remains unsatisfactory, particularly as it affects branching. This thesis concludes with a suggested breeding scheme involving both sexual and asexual propagation of material being tested in recently established provenance trials
Pires, Ana Marta Costa. « Free light chain : a marker of disesase and intraclonal heterogeneity indicator in intact immunoglobulin multiple myeloma ». Master's thesis, 2019. https://hdl.handle.net/10216/124600.
Texte intégralPires, Ana Marta Costa. « Free light chain : a marker of disesase and intraclonal heterogeneity indicator in intact immunoglobulin multiple myeloma ». Dissertação, 2019. https://hdl.handle.net/10216/124600.
Texte intégralChapitres de livres sur le sujet "Intraclonal"
Rainey, Paul B., Ian P. Thompson et E. Richard Moxon. « Intraclonal Polymorphism in Bacteria ». Dans Advances in Microbial Ecology, 263–300. Boston, MA : Springer US, 1993. http://dx.doi.org/10.1007/978-1-4615-2858-6_6.
Texte intégralActes de conférences sur le sujet "Intraclonal"
Jakubikova, Jana, Danka Cholujova, Teru Hideshima, Jacob Laubach, Nikhil C. Munshi, Steven P. Treon, Paul G. Richardson, Efstathios Kastritis, David M. Dorfman et Kenneth C. Anderson. « Abstract 2004 : Phenotypic and molecular characterization of inter- and intraclonal heterogeneity in multiple myeloma and Waldenstrom macroglobulinemia ». Dans Proceedings : AACR 106th Annual Meeting 2015 ; April 18-22, 2015 ; Philadelphia, PA. American Association for Cancer Research, 2015. http://dx.doi.org/10.1158/1538-7445.am2015-2004.
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