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1

Rodrigues, H. de Oliveira, J. Julio Vicente et Delir Corrêa Gomes. « Strongyloides ferreirai sp.n. (Nematoda, Rhabdiasoidea) parasito do roedor Kerodon rupestris (Wied.) no Brasil ». Memórias do Instituto Oswaldo Cruz 80, no 4 (décembre 1985) : 407–10. http://dx.doi.org/10.1590/s0074-02761985000400005.

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É descrita uma nova espécie de nematóide do gênero Strongyloides Grassi, 1879, Strongyloides ferreirai sp.n. parasita do instestino delgado de Kerodon rupestris (Wied.) proveniente de Floriano Peixoto, Estado do Piauí. Esta é a primeira referência deste gênero parasitando roedor caviideo no Brasil.
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Horny, H. P., et H. A. Horst. « Lymphoreticular Infiltrates in Adenocarcinoma of the Large Instestine ». Pathology - Research and Practice 182, no 2 (avril 1987) : 222–27. http://dx.doi.org/10.1016/s0344-0338(87)80108-5.

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Moreno-Osset, Eduardo. « Ser y no ser del síndrome del instestino irritable ». Medicina Clínica 117, no 7 (janvier 2001) : 257–59. http://dx.doi.org/10.1016/s0025-7753(01)72079-9.

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Liu, Guanwen, Bing Pang, Na Li, Han Jin, Junjun Li, Wanqin Wu, Chongyang Ai, Chunmei Jiang et Junling Shi. « Therapeutic effect of Lactobacillus rhamnosus SHA113 on intestinal infection by multi-drug-resistant Staphylococcus aureus and its underlying mechanisms ». Food & ; Function 11, no 7 (2020) : 6226–39. http://dx.doi.org/10.1039/d0fo00969e.

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Ferreira de Morais, Fernanda, José Diego Marques Santos, Samuel Oliveira de Vera, Raiane Gomes Araújo Oliveira, Elaine Maria Leite Rangel Andrade et Sarah Nilkece Mesquita Araújo. « Management of instestinal stomas : knowledge of the caregiver ». O Mundo da Saúde 42, no 4 (20 décembre 2018) : 823–44. http://dx.doi.org/10.15343/0104-7809.20184204823844.

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Eide, Tor J. « A morphometrical analysis of dysplasia in small adenomas of the large instestine ». Virchows Archiv A Pathological Anatomy and Histopathology 410, no 2 (1987) : 119–24. http://dx.doi.org/10.1007/bf00713515.

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Konarska, L., et L. Tomaszewski. « Studies on l-arginase in developing rat small instestine, brain, and kidney ». Biochemical Medicine and Metabolic Biology 35, no 2 (avril 1986) : 156–69. http://dx.doi.org/10.1016/0885-4505(86)90070-8.

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Chiocchetti, Gabriela Matuoka, Dinoraz Vélez Pacios et Vicente Devesa Pérez. « Instestinal toxicity of a subchronic exposure to inorganic arsenic ». Toxicology Letters 280 (octobre 2017) : S179. http://dx.doi.org/10.1016/j.toxlet.2017.07.502.

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Neves, José de Souza, José Eduardo de Aguilar Nascimento, Maria Helena Gaiva Gomes da Silva, Alberto Salomão Bicudo, Mariana Nascimento et Rubens Nochi Junior. « Influência da glutamina na mucosa do instestino de ratos submetidos à enterectomia extensa ». Revista do Colégio Brasileiro de Cirurgiões 30, no 6 (décembre 2003) : 406–15. http://dx.doi.org/10.1590/s0100-69912003000600002.

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OBJETIVO: Avaliar a influência de uma dieta suplementada com glutamina sobre as alterações adaptativas no intestino delgado de ratos com enterectomia extensa. MÉTODO: Vinte ratos Wistar, divididos aleatoriamente em dois grupos de dez animais, foram enterectomizados e alimentados com dois tipos diferentes de dieta nos 14 dias de pós-operatório: grupo controle (GC)-dieta padrão; grupo glutamina (GG)-dietapadrão acrescida de 3,05% de glutamina. Avaliou-se evolução ponderal, peso da mucosa intestinal (PM), profundidade das criptas (PC), altura das vilosidades (AV), espessura da parede (EP) e o conteúdo de ácido desoxirribonucléico (DNA) na mucosa intestinal, no início e no final do experimento. RESULTADOS: Com exceção da PC ileal do Grupo GG, todas as variáveis estudadas tiveram um aumento significativo em seus valores finais tanto no jejuno quanto no íleo (p<0,05).Entre os grupos, a comparação do PM, AV, DNA da mucosa, no jejuno e no íleo, tanto inicialmente quanto no final do estudo, bem como da EP inicial no jejuno e íleo eda PC no jejuno final e no íleo inicial e final não mostraram diferenças significativas (p>0,05). No jejuno inicial, a PC no grupo GC foi maior (p=0,005). A EP do jejuno e íleo final foi maior no grupo GC. CONCLUSÃO: A suplementação dietética com a glutamina não melhorou as alterações adaptativas que ocorrem no remanescente intestinal.
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Assis Rodrigues, Maria Luiza, Sirlene Souza Rodrigues Sartori, Priscila Izabel Santos Totaro et Sérgio Luis Pinto da Matta. « Hystometric evaluation of nickel chronic exposure effects on large instestine of adult Wistar male rats ». Revista de Ciencias Agrícolas 36, E (16 octobre 2019) : 21–30. http://dx.doi.org/10.22267/rcia.1936e.103.

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The ingestion of considerable amounts of water or food contaminated with nickel can be very toxic. The present work was conducted aiming to evaluate the effects of nickel exposures on ascending colon of adult Wistar male rats at hystometric level. We used 12 animals that were divided in a control (ingested uncontaminated water) and a nickel-contaminated (i.e., 25 mg de nickel/L of water) groups. Nickel chloride was offered in declorinated water and the experiment had a 56 days exposure period. A portion of the ascending colon was removed of the animals and subjected to hystological labelling processes using blue toluidin (for general hystometric description), Alcian Blue (AB, for acid mucins) and periodic acid-Schiff (PAS) technique (for neutral mucins). The potential differences between groups were desgined by applying the Whitney test and t test (p < 0.05). The crypts were smaller for the nickel-contaminated group, even though these organism exhibited broader and higher crypts. Nickel-contaminated animals exhibited a smaller amount of calyceform cells with AB and PAS positive reactions as well as a less mucus quantities when compared with nickel-uncontaminated animals. Such reductions on the amount of calyceform cells with AB and PAS positive reactions may be related wiht the shallower crypts, which possibly reduced the synthesis and secretion of mucins, compromissing the functional aspects (e.g., lubrification and intestinal mucosa protection) of the nickel-contaminated large intestines. Interestingly, the wider and higher crypts and higher epithelium collumn on the nickel-contaminated animals may represent a relevant trade-off for the intestinal mucosa protection.
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Nahas, Sergio Carlos, Carlos Frederico Sparapan Marques, Sérgio Alonso Araújo, Adilson Akihide Aisaka, Caio Sérgio Rizkallah Nahas, Rodrigo Ambar Pinto et Desidério Roberto Kiss. « Colonoscopia como método diagnóstico e terapêutico das moléstias do instestino grosso : análise de 2.567 exames ». Arquivos de Gastroenterologia 42, no 2 (juin 2005) : 77–82. http://dx.doi.org/10.1590/s0004-28032005000200003.

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RACIONAL: Com o surgimento das fibras ópticas na área médica, houve grande avanço tecnológico na observação do aparelho digestivo, com a introdução dos endoscópios flexíveis, usados anteriormente para o trato digestivo superior. OBJETIVO: Rever os resultados da aplicação da colonoscopia diagnóstica e terapêutica na Disciplina de Coloproctologia da Faculdade de Medicina da Universidade de São Paulo, respeitando as características de instituição de ensino e aprimoramento médico. CASUÍSTICA E MÉTODOS: Análise retrospectiva dos dados referentes a 2.567 exames de fibrocolonoscopia realizados entre os anos de 1984 e 2002, seja em regime de internação hospitalar ou ambulatorial. As principais indicações de exame nesta casuística foram o sangramento retal/anemia em 571 (22,24%) doentes, alteração do hábito intestinal em 379 (14,76%), moléstia inflamatória em 222 (8,65%) e pós-operatório de neoplasia em 186 (7,25%). O preparo intestinal com manitol foi realizado na maioria dos doentes. A sedação, quando não contra-indicada, foi feita com meperidina e benzodiazepínico. Todos exames foram feitos com monitorização com oxímetro de pulso. RESULTADOS: O resultado do exame foi normal em 1.089 (42,42%) casos. Pólipos foram diagnosticados em 397 (15,47%) casos, doença diverticular em 330 (12,86%), doença inflamatória em 305 (11,88%) e câncer colorretal em 262 (10,21%). Foram realizadas 819 polipectomias em 397 doentes, gerando a média de 2,21 polipectomias por doente com pólipo. A colonoscopia foi considerada incompleta (quando não atingiu o ceco) em 181 (7,05%) casos. Houve um caso de perfuração por fratura de tumor subestenosante de retossigmóide. Complicações relacionadas à sedação levaram à interrupção do exame em 0,42% das vezes, sem maiores prejuízos aos pacientes. CONCLUSÃO: A colonoscopia foi método eficaz no diagnóstico e tratamento de afecções colorretais, sendo seguro e com baixo índice de morbidade em ambiente universitário.
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KOBAYASHI, Ryo, Toshiaki SAKAI, Manabu ONO et Shigeo KATO. « 20705 A Study on Brake Characteristics of In-Pipe Mobile Microrobot Movable in the Instestine ». Proceedings of Conference of Kanto Branch 2010.16 (2010) : 217–18. http://dx.doi.org/10.1299/jsmekanto.2010.16.217.

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Mattes, B. R., S. de A. S. Consiglio, B. Z. de Almeida, M. C. Guido, R. B. Orsi, R. M. da Silva, A. Costa, A. J. P. Ferreira et T. Knöbl. « INFLUÊNCIA DA BIOSSEGURANÇA NA COLONIZAÇÃO INSTESTINAL POR ESCHERICHIA COLI EM PSITACÍDEOS ». Arquivos do Instituto Biológico 72, no 1 (mars 2005) : 13–16. http://dx.doi.org/10.1590/1808-1657v72p0132005.

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RESUMO Escherichia coli não é um componente da microbiota entérica de psitacídeos e a presença da bactéria nestas aves está associada à ocorrência de diarréias, doenças respiratórias e septicemias. Este trabalho avaliou a colonização intestinal por Escherichia coli em psitacídeos criados sob diferentes condições de biossegurança. Foram analisados 85 “swabs” de cloaca, através de exames bacteriológicos (cultura, isolamento e identificação bioquímica). Os resultados mostraram diferenças significativas na colonização intestinal por E. coli em psitacídeos, com 20% (10/50) de aves positivas no criatório conservacionista e 80% (28/35) no criatório recreacionista. Os dados evidenciam a importância da biossegurança, uma vez que o estado sanitário das aves alojadas em cativeiro pode ser influenciado pela finalidade do criatório.
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Ranjan D, Dr Siva, et Dr Majety Dora Venkata Ramnath. « A Study on Gastro Instestinal Stromal Tumors : A Risk of Metastasis ». Saudi Journal of Pathology and Microbiology 5, no 6 (21 juin 2020) : 319–22. http://dx.doi.org/10.36348/sjpm.2020.v05i06.003.

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Mortuaire, Geoffrey, Xavier Leroy, Claire Vandenhende-Szymanski, Dominique Chevalier et Anne-Sophie Thisse. « Comparison of endoscopic and external resections for sinonasal instestinal-type adenocarcinoma ». European Archives of Oto-Rhino-Laryngology 273, no 12 (30 juin 2016) : 4343–50. http://dx.doi.org/10.1007/s00405-016-4181-4.

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Sjofjan O., Adli D.N., Hanani P.K. et Sulistiyaningrum D. « THE UTILIZATION OF BAY LEAF (SyzygiumpolyanthumWalp) FLOUR IN FEED ON CARCASS QUALITY, MICROFLORA INSTESTINE OF BROILER ». International Journal of Engineering Technologies and Management Research 6, no 11 (25 janvier 2020) : 1–9. http://dx.doi.org/10.29121/ijetmr.v6.i11.2019.458.

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The research purpose was to determine the utilization of bay meal (SyzygiumpolyanthumWalp) microflora, and carcass quality of broiler. The research method was used completely randomized design with 5 treatments and 4 replicates. The materials used for this research were 80 unsex 15 days old with average body weight 307.725±22.17 g/head. The treatments used for research were dietary with T0 (basal feed), T1 (basal feed + 1% bay leaf meal), T2 (basal feed + 2% bay leaf meal), T3 (basal feed + 3% bay leaf meal), T4 (basal feed + 4% bay leaf meal). The parameters observed were intestinal characteristic bacteria (lactic acid bacteria, Escherichia coli, and Salmonella sp.) and (carcass percentage, abdominal fat, organ visceral weight, breast meat cholesterol). The data analysis was the analysis of variance (anova) and continued by Duncan Multiple Range Test. The results showed that using bay leaf effect as in feed has significant difference (P<0.05) on lactic acid bacteria and Escherichia coli and significantly different (P<0.01) (breast meat cholesterol) but didn’t significant difference (P>0.05) on carcass percentage, abdominal fat and organ visceral weight. The addition of 4% bay leaf gave the best effect on microflora, and breast cholesterol quality of broiler.
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Koivu-Tikkanen, Terhi J., Leon J. Schurgers, Henk H. W. Thijssen et Cees Vermeer. « Intestinal, hepatic, and circulating vitamin K levels at low and high intakes of vitamin K in rats ». British Journal of Nutrition 83, no 2 (février 2000) : 185–90. http://dx.doi.org/10.1017/s0007114500000234.

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The aim of the present study was to assess how high doses of dietary vitamin K influence the intestinal profile of K-vitamins in vitamin K-deficient rats, and whether the induced changes are reflected in the hepatic vitamin K store. Vitamin K-deficient rats were fed for 10 d on diets containing different forms of vitamin K, and it was determined how these diets affected the vitamin K concentration at various sites of the instestine, serum, and the liver. It was found that the absorption of phylloquinone from standard food is not more than 10 %, while the absorption of pharmacological doses of oil-solubilized phylloquinone and menaquinone-4 was also far from complete (18 and 55 % respectively). High intakes of phylloquinone suppress the colonic production of all higher menaquinones. High menaquinone-4 intake induces very high menaquinone-8 concentrations, both in the colonic contents as well as in the liver. These data suggest that menaquinone-4 may be converted into menaquinone-8 (but not into other menaquinones) via a metabolic pathway which has not been reported previously.
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Lördal, M., et P. M. Hellström. « Serotonin induces phase III of the MMC, VIA 5-HT3-receptors dependent on cholinergic mechanisms in the small instestine ». Gastroenterology 114 (avril 1998) : A795. http://dx.doi.org/10.1016/s0016-5085(98)83246-0.

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Koneru, Gopala, Ajay Kaul, Harsh Kothari, Khalil El-Chammas et Vamsi K. Kantamaneni. « Tu1771 FACTORS IN ESTABLISHMENT OF ENTERAL AUTONOMY IN CHILDREN WITH INTESTINAL AGANGLIONOSIS AND INSTESTINAL FAILURE ». Gastroenterology 158, no 6 (mai 2020) : S—1154. http://dx.doi.org/10.1016/s0016-5085(20)33559-9.

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Mikhail Yuryevich, Syromyatnikov, Shabunin Sergey Viktorovich, Nesterova Ekaterina Yuryevna, Gladkikh Mariya Ivanovna, Smirnova Yuliya Dmitrievna, Burakova Inna Yuryevna, Morozova Polina Dmitrievna, Gryaznova Mariya Vladimirovna et Mikhaylov Evgeniy Vladimirovich. « STUDY OF THE FUNGAL MICROBIOME DIVERSITY OF THE INSTESTINES IN PIGS AT VARIOUS FEED CONVERSION ». BULLETIN OF VETERINARY PHARMACOLOGY 4, no 25 (2023) : 151–62. http://dx.doi.org/10.17238/issn2541-8203.2023.4.151.

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ZaidiZaidi, Nurul Amni, Azzmer Azzar Abdul Hamid et Tengku Haziyamin Tengku Abdul Hamid. « Lactic acid bacteria with antimicrobial properties isolated from the instestines of japanese quail (Coturnix Coturnix Japonica) ». Science Heritage Journal 1, no 1 (10 janvier 2017) : 10–12. http://dx.doi.org/10.26480/gws.01.2017.10.12.

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Khan, Yasmeen, S. K. Mohanty, Hemant Kumar et Sachin Pandey. « Upper Gastro Instestinal Endoscopic Findings In Patients With Dyspepsia : Our Experience At Cims, Bilaspur, Chhattisgarh, India ». IOSR Journal of Dental and Medical Sciences 13, no 5 (2014) : 08–12. http://dx.doi.org/10.9790/0853-13560812.

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Tawfeek, F. Kh, et Gh A. Taqa. « Effect of Aqueous Extract of Nigella Sativa seeds on Body Weight,Blood Glucose And Average Transit In Albino Rat Small Instestine ». JOURNAL OF EDUCATION AND SCIENCE 17, no 2 (1 juin 2005) : 73–79. http://dx.doi.org/10.33899/edusj.2005.81315.

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Felippi, Renata Serravalle, Rita Franca, Luciana Rodrigues Silva et Cibele Dantas Marques. « Prevalência de constipação intestinal em pacientes com obesidade acompanhados no ambulatório de um Hospital Pediátrico ». Revista de Ciências Médicas e Biológicas 13, no 2 (5 janvier 2015) : 152. http://dx.doi.org/10.9771/cmbio.v13i2.6515.

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<p class="MsoNormal" style="text-align: justify;">A constipação intestinal é um problema freqüente na infância assim como a obesidade, que vem crescendo e se tornando um dos maiores desafios para o pediatra. Objetivo: estudar a freqüência de obstipação intestinal em pacientes obesos pediátricos e descrever suas características clínicas. Métodos: estudo descritivo no qual 77 crianças atendidas no ambulatório de obesidade do Centro Pediátrico Professor Hosannah de Oliveira (CPPHO), com idades entre 6 e 17 anos compuseram a amostra. O IMC foi adotado para classificar obesidade e sobrepeso. Os critérios para definir obstipação foram baseados nos Critérios de Roma III. Resultados: a prevalência de constipação instestinal foi de 15,5%. Dos 77 pacientes, 12 apresentavam freqüência fecal menor ou igual a 3 vezes por semana, dor ao defecar, fezes endurecidas, pétreas ou em cíbalos , ou presença de sangue. Conclusão: esse estudo mostra que há uma relação importante entre obesidade e constipação. Essa relação é importante pelo alto risco de desenvolver problemas psicosociais e doenças orgânicas como diabetes, hiperlipidemia, hipertensão arterial, esteatohepatite.</p>
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Gandhi, M. P. S., et S. P. Ahuja. « Absorption of Xanthine Oxidase from the Instestines of Rats and Rabbits and its Role in initiation of Atherosclerosis ». Zentralblatt für Veterinärmedizin Reihe A 26, no 8 (13 mai 2010) : 635–42. http://dx.doi.org/10.1111/j.1439-0442.1979.tb01641.x.

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Blevrakis, Evangelos, Maria Raissaki, Sofia Xenaki, Elissavet Astyrakaki, Nelli Kholcheva et Emmanuel Chrysos. « Multiple magnet ingestion causing instestinal obstruction and entero-enteric fistula : Which imaging modality besides radiographs ? A case report ». Annals of Medicine and Surgery 31 (juillet 2018) : 29–33. http://dx.doi.org/10.1016/j.amsu.2018.04.033.

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Mangunsong, Sonlimar, et Resi Sukma Melati. « Efek Laksatif Ekstrak Etanol Daun Keji Beling (Strobilanthes Crispus Bi.) Dengan Metode Transit Intestinal Terhadap Tikus Putih Jantan (Rattus Norvegicus) Yang Diinduksi Dengan Gambir ». JKPharm Jurnal Kesehatan Farmasi 2, no 1 (7 juin 2023) : 69–74. http://dx.doi.org/10.36086/jkpharm.v2i1.1772.

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Konstipasi adalah ketidakmampuan melakukan evaluasi tinja secara sempurna. Penyebab konstipasi seringterjadi karena faktor risiko asupan serat yang rendah. Secara empiris tanaman keji beling dapat digunakansebagai laksatif. Tanaman keji beling mengandung senyawa alkaloid dan saponin yang berkhasiat sebagaidiuretik, emoliens dan laksatif. Menyadari fakta tersebut, peneliti merasa perlu untuk melakukan penelitianmengenai efek laksatif terhadap ekstrak daun keji beling. Penelitian ini bersifat eksperimental menggunakanhewan percobaan tikus putih jantan sebanyak 30 ekor yang dibagi menjadi enam kelompok. Kelompok I(kontrol normal), kelompok II (kontrol negatif), kelompok III (perlakuan suspensi ekstrak dosis I 20 mg/200grBB), kelompok IV (perlakuan suspensi ekstrak dosis II 40 mg/200 grBB), kelompok V (perlakuan suspensiekstrak dosis III 80 mg/200 grBB), dan kelompok VI (kontrol positif, diberi suspensi bisacodyl 0,09 mg/200kgBB). Efek laksatif dibuktikan dengan metode transit instestinal yaitu mengukur rasio panjang lintasan markernorit pada usus terhadap panjang keseluruhan usus tikus. Penelitian ini menunjukkan perbedaan yangsiginifikan antara kontrol positif dengan kontrol negatif, normal, dosis I dan dosis II, namun tidak pada dosisIII (p>0,05) yang berarti dosis III memiliki efek laksatif. Ekstrak etanol daun keji beling (Strobilanthes crispusBI.) yang memiliki efek laksatif secara signifikan (p>0,05) dengan positif yaitu dosis III 80 mg.
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Mangunsong, Sonlimar, et Res Sukma Melati. « Efek Laksatif Ekstrak Etanol Daun Keji Beling (Strobilanthes Crispus Bi.) Dengan Metode Transit Intestinal Terhadap Tikus Putih Jantan (Rattus Norvegicus) Yang Diinduksi Dengan Gambir ». JKPharm Jurnal Kesehatan Farmasi 2, no 1 (1 juin 2020) : 69–74. http://dx.doi.org/10.36086/jkpharm.v2i1.1773.

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Konstipasi adalah ketidakmampuan melakukan evaluasi tinja secara sempurna. Penyebab konstipasi seringterjadi karena faktor risiko asupan serat yang rendah. Secara empiris tanaman keji beling dapat digunakansebagai laksatif. Tanaman keji beling mengandung senyawa alkaloid dan saponin yang berkhasiat sebagaidiuretik, emoliens dan laksatif. Menyadari fakta tersebut, peneliti merasa perlu untuk melakukan penelitianmengenai efek laksatif terhadap ekstrak daun keji beling. Penelitian ini bersifat eksperimental menggunakanhewan percobaan tikus putih jantan sebanyak 30 ekor yang dibagi menjadi enam kelompok. Kelompok I(kontrol normal), kelompok II (kontrol negatif), kelompok III (perlakuan suspensi ekstrak dosis I 20 mg/200grBB), kelompok IV (perlakuan suspensi ekstrak dosis II 40 mg/200 grBB), kelompok V (perlakuan suspensiekstrak dosis III 80 mg/200 grBB), dan kelompok VI (kontrol positif, diberi suspensi bisacodyl 0,09 mg/200kgBB). Efek laksatif dibuktikan dengan metode transit instestinal yaitu mengukur rasio panjang lintasan markernorit pada usus terhadap panjang keseluruhan usus tikus. Penelitian ini menunjukkan perbedaan yangsiginifikan antara kontrol positif dengan kontrol negatif, normal, dosis I dan dosis II, namun tidak pada dosisIII (p>0,05) yang berarti dosis III memiliki efek laksatif. Ekstrak etanol daun keji beling (Strobilanthes crispusBI.) yang memiliki efek laksatif secara signifikan (p>0,05) dengan positif yaitu dosis III 80 mg.
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Pitisuttithum, Panyavee, Tanisa Patcharatrakul, Duangporn Werawatganon et Sutep Gonlachanvit. « Su1104 – A Randomized Controlled Study on the Effects of Curcuminoid on Instestinal Permeability Evaluated by Urine Lactulose Mannitol Ratio (LMR) After Aspirin Ingestion ». Gastroenterology 156, no 6 (mai 2019) : S—504. http://dx.doi.org/10.1016/s0016-5085(19)38136-3.

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Mello, Hurzana de, Julieta R. E. Moraes, Ines Garcia Niza, Flávio Ruas de Moraes, Rodrigo O. A. Ozório, Marina Tie Shimada, Jair R. Engracia Filho et Gustavo S. Claudiano. « Efeitos benéficos de probióticos no intestino de juvenis de Tilápia-do-Nilo ». Pesquisa Veterinária Brasileira 33, no 6 (juin 2013) : 724–30. http://dx.doi.org/10.1590/s0100-736x2013000600006.

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Os objetivos deste trabalho foram os de avaliar o percentual de sobrevivência, a microbiota instestinal, a integridade da mucosa, e a qualidade da carcaça de juvenis de Tilápias-do-Nilo, Oreochromis niloticus, após 80 dias de alimentação com dieta contendo aditivo probiótico (Bacillus cereus 4,0x10(8) UFCg-1 e Bacillus subtilis 4,0x10(8) UFCg-1), na proporção de 4g/kg de ração peletizada. O delineamento experimental foi inteiramente casualizado com dois tratamentos, sendo um grupo controle e outro alimentado com dieta adicionada de probiótico. Foram realizados os cálculos do percentual de sobrevivência relativa, análise da microbiota intestinal por cultura microbiológica, análise histomorfométrica da mucosa intestinal e análise químico-bromatológica da carcaça dos peixes. Os resultados demonstraram que as tilápias do grupo tratado apresentaram percentual de sobrevivência relativa maior (P<0,05) que o do grupo controle e colonização intestinal por B. cereus e B. subtilis com maior (P<0,05) número de unidades formadoras de colônia em relação ao grupo controle. A análise histomorfométrica demonstrou que o grupo alimentado com aditivo probiótico apresentou vilosidades mais altas e mais largas, além de maior número de células caliciformes que o observado no grupo controle (P<0,05). Em relação à qualidade de carcaça os resultados demonstraram que houve interferência positiva (P<0,05) do probiótico no grupo tratado em relação ao controle quanto aos teores de proteína e extrato etéreo. Estes resultados permitem inferir que a suplementação com probiótico, como testado neste estudo, induziu a colonização intestinal por bactérias benéficas e promoveu maior percentual de sobrevivência relativa, diminuiu a descamação da mucosa, e favoreceu o aumento do número de células caliciformes.
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Chaudhuri, K. R., J. Boyd, J. Acosta, L. Bergmann, P. Kukreja et A. Antonini. « Utilization of COMT inhibitors, dopamine agonists, and MAO-B inhibitors with levodopa-carbidopa instestinal gel in advanced Parkinson's disease patients : Summary of phase 3 and real-world studies ». Journal of the Neurological Sciences 405 (octobre 2019) : 29–30. http://dx.doi.org/10.1016/j.jns.2019.10.266.

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Pereira, C. R., C. I. Ghanem, R. Silva, M. D. Araújo, S. G. Monteiro, A. G. Casanova, S. Chhann, E. Sousa, M. D. L. Bastos et F. Remião. « The effects of 1-(propan-2-ylamino)-4-propoxy-9H-thioxanthen-9-one (TX5) on P-glycoprotein activity and expression in the rat instestinal mucosa : An ex vivo and in vivo approach ». Toxicology Letters 295 (octobre 2018) : S268. http://dx.doi.org/10.1016/j.toxlet.2018.07.027.

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Grothe, Wilfried, Martin Bauer, Andreas Rupprecht, Maximillian Christopeit, Anke Muetherig, Thomas Weber, Sebastian Theurich, Mike Becker et Gerhard Behre. « Keratinocyte-Growth-Factor-Prophylaxis : Positive Effect on Intestinal Mucositis Following Autologous and Allogeneic Peripheral Blood Stem Cell Transplantation in Haemtological Malignancies : A Sequential Cohort Study. » Blood 110, no 11 (16 novembre 2007) : 4953. http://dx.doi.org/10.1182/blood.v110.11.4953.4953.

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Abstract Introduction: Keratinocyte Growth factor (KGF) prophylaxis reduces the extent and duration of mucosal barrier injury following intensive chemotherapy. Following this prophylaxis a marked reduction of infections and consecutively the need for antibiotic treatment can be observed. The extent of oral mucositis (OM) is easely to access. The extent of instestinal musocitis (IM) is more difficult to determine: The serum level of Citrulline, an intermediate product of the uric acid cycle mainly synthesized in the small intestine, serves as a marker of small intestine injury. Aim of the present study was to determine the extent of OM and IM before and after the introduction of KGF-prophylaxis in their treatment. METHODS: In 09/2006 KGF (60μg/kg body weight per day, for 3 days before conditioning therapy respectively after HSCT) was introduced at our institution on a compassionate use basis. Five months before the introduction and thereafter the extent of OM and IM in autologous and allogeneic HSCT was evaluated prospectively. Beside routine clinical and laboratory values including the daily oral mucositis score (DMS) and daily gut score (DGS) the plasma citrulline level was determined in week 1 (W1), week 2 (W2) and week 3 (W3) following HSCT. Moreover the dosage of therapeutic intravenous (i.v.) antibiotic treatment with meropeneme, piperacilline/combactam and teicoplanin in addition to antibiotic prophylaxis was noted. Pt with oropharyngeal radiotherapy were excluded from analysis. RESULTS: Until 04/2007 36 pt were evaluated. 27 pt underwent autologous and 9 allogeneic HSCT. 13 of the autologous and 6 of the allogeneic transplanted pt received KGF. In pt with KGF clinically significant OM and moderate to severe IM were seen less often (W1: 1/19 pt vs. 3/17 pt and W2: 1/19 pt vs. 2/17 pt without KGF). These differences were statistically non significant. Citrulline serum levels (in μmol/l) were significantly higher in pt receiving KGF (W2: average 16.8 vs. 15.9 in pt without KGF (p = 0.02)). The therapeutic use of i.v. antibiotics was lower for pt receiving KGF (average of 10.5 days vs. 26.8 days for pt without KGF (p = 0.0001)). Subgroup analysis confirmed the described tendencies in autologous HSCT. SUMMARY: Even in this small number of pt a positive effect of KGF on oral and intestinal mucositis was detectable. The reduced need for therapeutic i.v. antibiotics seen as a tendency in this study should be re-evaluated in a prospective pharmacoeconomic study to prove cost effectiveness of KGF treatment.
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Broussais, Florence, Diane Coso, Vadim Ivanov, Thérèse Aurran, Anne-Marie Stoppa et Reda Bouabdallah. « A Restrospective Review of Peripheral T-Cell Lymphoma in a Single Institution Between 2000 and 2010 ». Blood 118, no 21 (18 novembre 2011) : 1623. http://dx.doi.org/10.1182/blood.v118.21.1623.1623.

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Abstract Abstract 1623 Background: Peripheral T-cell non-hodgkin lymphomas (NHL) comprise a heterogeneous group of malignancies, characterized by an aggressive disease course and a poor clinical outcome. T-cell lymphomas present in lymph nodes and they also frequently involve extra nodal sites. The first line treatment consists in CHOP-like regimen. Consolidation treatment in first line or in relapse is autologous stem cell transplantation (ASCT) or allogenic stem cell transplantation (SCT). Patients and methods: We retrospectively analysed the data of 189 adults who had received chemotherapy in our institution between 2000 and 2010. Results: Median age at time of presentation was 55 (range 17–89) years, 76% were <65 years. 50% had B symptoms and 50% serum elevated LDH. ECOG was 0–1 in 60% and 2–4 in 40%. According to the Ann Arbor classification, 15% were stage I-II and 85% were stage III-IV. 50% had low IPI (0-1-2) and 50% had elevated IPI (3-4-5). The histologic subtypes were 42% peripheral T-cell NHL unspecified (PTCL-U), anaplastic large cell lymphoma (ALCL), 8% had ALK+ and 10% had ALK-, 24% angioimmunoblastic lymphoma (AILT), 3% transformed mycosis fungoide, 2% instestinal T-cell lymphoma, 2% hepatosplenic γδ T-cell lymphoma and 1% adult T-cell lymphoma/leukemia. Primary extranodal lymphoma represented 17% and 8% were diagnosed with hemophagocytosis. Five-year overall survival (OS) was 28.3% (21.8–36.8%), and five-year progression free survival (PFS) was 18.4% (13.1–25.7%). On multivariate analysis, ALCL-ALK+ (p=0.008), AILT (p<0.001), extranodal involvement (p=0.01), PS>1 (p<0.001), LDH>N (p=0.003) were independent adverse factors for OS. Moreover B symptoms (p<0.01) was a significant factor for PFS. 86% received CHOP-like induction treatment. The median number of chemotherapy was 2 (1–7). 59% experienced a complete response during the therapeutic procedure, while 22% were primary refractory. 44% had ASCT and 14% allogenic SCT. Only 28% of patients referred for allogenic SCT received this treatment. Conclusions: This 10-year review of patients treated in a single institution with initial conventional chemotherapy followed by more intensive treatments confirms the poor OS and PFS in the case of T-cell lymphoma. Despite a low incidence, T-cell lymphoma could be a priority area of research for new treatments with a potential to improve OS and PFS. Disclosures: No relevant conflicts of interest to declare.
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Murwaningrum, Artati, Murdani Abdullah et Dadang Makmun. « Pendekatan Diagnosis dan Tatalaksana Tuberkulosis Intestinal ». Jurnal Penyakit Dalam Indonesia 3, no 3 (23 janvier 2017) : 165. http://dx.doi.org/10.7454/jpdi.v3i3.28.

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Tuberkulosis (TB) telah menjadi masalah global yang terus membesar seiring dengan bertambahnya jumlah pasien TB. Infeksi TB masih merupakan hal yang umum ditemukan dan merupakan faktor penting terhadap angka kesakitan dan kematian, terutama pada negara yang belum dan sedang berkembang. Kasus Tuberkulosis usus (TB usus) juga meningkat seiring dengan meningkatnya jumlah kasus TB secara umum. Indonesia merupakan Negara ke-2 dengan prevalensi Tuberkulosis TB tertinggi di Asia Tenggara setelah Timor Leste pada tahun 2014. TB usus adalah manifestasi TB ekstrapulmonal terbanyak keenam.Manifestasi klinis yang tidak spesifik dan kadang menyerupai beberapa kondisi lain termasuk keganasan menyebabkan diagnosis TB usus sulit ditegakkan secara akurat. Temuan dari hasil endoskopi dan gambaran radiologi dari berbagai stage penyakit sudah sangat banyak, namun diagnosis tetap sulit dilakukan. Sampai saat ini belum ada metode tunggal yang dapat mendeteksi TB usus secara tepat dan akurat, berbagai metode investigasi telah digunakan dalam diagnosis TB usus. Diagnosis yang dilakukan sejak awal, pemberian terapi anti tuberculosis dan tindakan bedah adalah hal-hal esensial dalam pencegahan terjadinya kesakitan dan kematian akibat TB usus, sehingga dibutuhkan kombinasi penilaian klinis dan pemeriksaan berbagai modalitas. Pasien yang telah didiagnosis TB usus diberikan terapi obat anti tuberculosis (OAT) dan pertimbangan tindakan bedah jika mengalami komplikasi.Kata Kunci: diagnosis, tuberkulosis intestinal Diagnostic Approach and Treatment of Instestinal TuberculosisTuberculosis (TB) has become a resurgent global problem with increasing numbers of patients. TB infection is still common and remains an important cause of morbidity and mortality, particularly in underdeveloped and developing nations. Intestinal tuberculosis (intestinal TB) rates are rising, consistet with the overall trend. In 2014 Indonesia has the second highest TB prevalence in South East Asia after Timor Leste. Intestinal TB is the sixth highest manifestation of extrapulmonal TB. Manifestations can be non-specific and mimic many conditions, including malignancies causes’ intestinal TB diagnosis more difficult to be accurately determined. Findings from endoscopy and radiological imaging are countless, and depend on the stage of the disease and the time at which investigations are carried out. Hence, diagnosis can be difficult. Until recently there is no single method to identify intestinal TB accurately, various investigative methods have been used to aid in the diagnosis of intestinal TB. Early diagnosis and initiation of antituberculous therapy and surgical treatment are essential to prevent morbidity and mortality. Combined clinical assessment and some modalities examinations are needed to determine intestinal TB. Patient whom has been diagnosed with intestinal TB will be given anti tuberculosis therapy and surgery if any complications occur. Keywords: diagnosis, intestinal tuberculosis
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Pimont, Nathália Miasato, Mariana da Silva Marques, Rafael Alves Santomauro, Regina Mitsuka-Breganó, ItalmarTeodorico Navarro et Fernanda Pinto-Ferreira. « Perfil de Cães Parasitados por Entamoeba spp. em Hospital Veterinário Escola ». Ensaios e Ciência C Biológicas Agrárias e da Saúde 27, no 4 (19 décembre 2023) : 473–76. http://dx.doi.org/10.17921/1415-6938.2023v27n4p473-476.

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Entamoeba spp. são protozoários transmitidos pela ingestão de água e alimentos contaminados por cistos, causando, principalmente, alterações gastrointestinais em humanos e animais. Apenas as espécies Entamoeba coli e Entamoeba histolytica possuem relevância na medicina veterinária. Apesar dos cães portadores não serem capazes de infectar outros animais ou seres humanos, sua importância não deve ser negligenciada, pois sua presença indica precariedade nas condições higiênico-sanitárias. O objetivo deste estudo foi relatar o perfil de cães parasitados por Entamoeba spp. residentes no município de Londrina e região, atendidos em hospital veterinário escola, durante os anos de 2020-2022. No total, foram analisados dados de 42 cães, sendo possível observar, após mapeamento dos endereços, uma distribuição homogênea de animais positivos no município. Em relação aos anos, observou-se aumento de 27,7% de casos relatados entre os anos de 2020 e 2021. Foi encontrado maior prevalência em fêmeas com 64,3% (27/42) e adultos, 45,2% (19/42). Vacinação e desverminação não foram realizadas em 66,7% e 47,6% dos animais. Êmese, 71,4% (30/42), apatia, 66,7% (28/42) e hematoquezia, 57,1% (24/42) foram os sinais clínicos mais comuns. Tendo em vista seu reflexo na saúde única é fundamental o controle epidemiológico deste parasita. Dessa forma, é necessária uma participação ativa dos médicos veterinários para conscientização dos tutores sobre a epidemiologia da afecção, pois dessa forma poderemos contribuir para a formação de cidadãos mais conscientes e melhorar a qualidade de vida dos animais. Palavras-chave: Ameba. Diarreia. Parasitos Intestinais. Saúde Única AbstractEntamoeba spp. are protozoa transmitted through the ingestion of water and food contaminated with cysts, mainly causing gastrointestinal disorders in humans and animals. Only Entamoeba coli and Entamoeba histolytica species have relevance in veterinary medicine. Although carrier dogs are not capable of infecting other animals or humans, their importance should not be neglected as their presence indicates poor hygienic-sanitary conditions. The aim of this study was to report the profile of dogs parasitized by Entamoeba spp. residing in the municipality of Londrina and surrounding areas, treated at a veterinary teaching hospital during the years 2020-2022. A total of 42 dogs' data were analyzed, and it was possible to observe, after mapping the addresses, a homogeneous distribution of positive animals in the municipality. Regarding the years, an increase of 27.7% in reported cases was observed between 2020 and 2021. Higher prevalence was found in females with 64.3% (27/42) and adults with 45.2% (19/42). Vaccination and deworming were not performed in 66.7% and 47.6% of the animals, respectively. Vomiting, 71.4% (30/42), apathy, 66.7% (28/42), and bloody stools, 57.1% (24/42), were the most common clinical signs. Considering its impact on One Health, it is essential to control the epidemiology of this parasite. Thus, active participation of veterinarians is necessary to raise awareness among pet owners about the epidemiology of the infection, as this can contribute to the formation of more conscientious citizens and improve the quality of life for animals. Keywords: Ameba. Diarrhea. Instestinal Parasites. One health.
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Azzolini, M., M. La Spina, A. Mattarei, C. Paradisi, M. Zoratti et L. Biasutto. « Soluble prodrugs for efficient instestinal delivery of resveratrol ». Planta Medica 80, no 16 (30 octobre 2014). http://dx.doi.org/10.1055/s-0034-1394827.

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Gathe, Pradnya Haribhau. « Evaluation of hepato-protective activity of Dãruharidrã ( Berberis aristata,DC) with special reference to Hepatitis (Bahupittakãmalã). » National Journal of Research in Ayurved Science 6, no 02 (28 février 2018). http://dx.doi.org/10.52482/ayurlog.v6i02.68.

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The main causes of hepatitis are health ignorance, increased hot and humid environment, lowering living status, unhygine causing various gastro-instestinal diseases mainly diarrheoa, viral hepatitis and many other diseases. The people are living in congested places in bad sanitation, eating roadside fast food, drinking polluted water etc. Along with hepatitis, alcoholism and alcoholic liver disorder are most leading disease in India. Carakãcãrya explain Dãruharidrã (Berberis aristata, DC)nin bahupittakãmalã (khoşthaśãkhãshrîtakãmalã). It has references in many granthãs with respect to bahupittakãmalã. It is useful in a vast range of diseases. It has properties like cholegouge, astringent, hepato-stimulant and hepato-protective which are useful in treating anorexia , dysentery, hepatitis and liver disorder. This study shows Dãruharidrã is very effective in viral hepatitis.
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Macena, Tharcilla Nascimento da Silva, Ana Cristina Socorro Tinoco et Waniara Aguilar de Oliveira. « Infecção do trato urinário no período gestacional ». Revista Mosaicum, no 18 (20 octobre 2013). http://dx.doi.org/10.26893/rm.v9i18.210.

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A infecção do trato urinário (ITU) é uma das infecções mais comuns durante o período gestacional. O fácil acesso das bactérias presentes na microbiota instestinal facilita a sua migração ao ânus e consequentemente ao trato urinário. Objetivou-se correlacionar as complicações das infecções do trato urinário com o período gestacional. A metodologia consistiu de uma pesquisa bibliográfica descritiva de caráter qualitativo, incluindo estudos desde 2000 a 2013. As ITUs podem causar sérias complicações tanto para mãe quanto para o feto, dentre estas complicações destacam-se; parto prematuro, recém-nascido de baixo peso, ruptura de membranas amnióticas, ou até mesmo a morte materno-fetal. Por isso, é de suma importância um monitoramento contínuo para que a infecção não evolua e traga consequências danosas tanto para a mãe quanto para o feto.
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Hassan, I. A., I. Abdulraheem, H. O. Emun et O. M. Omole. « Anti-bacterial Effect of Chrysophyllum albidum Phyto Extract ». European Journal of Medicinal Plants, 8 avril 2019, 1–7. http://dx.doi.org/10.9734/ejmp/2019/v27i330114.

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Aims: This study was carried out to investigate the antimicrobial activity of Chrysophyllum albidum leaves extract on selected Gastro-instestinal bacteria such as Salmonella typhimurium, Shigella dysentariae, Vibrio cholera, Escherichia coli and Clostridium perfringens. Methodology: The leaves were extracted using ethanol, methanol and distilled water; the concentration of the extracts employed were 100 mg/ml, 200 mg/ml, 400 mg/ml and 500 mg/ml respectively; however the leaf extracts of Chrysophyllum albidum were screened for anti-microbial activity using the in vitro cup-plate method of agar diffusion technique with concentration of 10-5cells/ml of the selected bacteria. Simultaneously, 30 µg tetracycline and 30 µg metronidazole were used as positive control. Results: The result showed that the most active among them is Tetracycline; followed by ethanolic extract, aqueous extract, methanolic extract and metronidazole extract respectively on the tested bacteria. Conclusion: This research justifies the traditional use of the leaves of Chrysophyllum albidum for the therapeutic purposes; hence can be commercialized by pharmaceutical outfit; if not for anything but its availability and readily for human consumption.
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Rahmadi, Mahardian, Zuhaela Iqbal, Ikbar Nanda Pratama, Rifky Anindita Karunia, Arina Derry Puspitasari, Khoirotin Nisak et Aniek Setiya Budiatin. « PEG-4000 Ameliorates morphine-induced constipation in mice through inhibition of AQP-3 mRNA Expression ». Research Journal of Pharmacy and Technology, 24 juillet 2023, 3331–38. http://dx.doi.org/10.52711/0974-360x.2023.00550.

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Morphine is μ-opioid receptor (MOR) agonist that is used clinically for patients suffering from moderate to severe pain. Morphine can cause constipation due to activation of μ-opioid receptors in the central nervous system and the nervous system in the gastrointestinal tract. It is caused by increasing the expression of AQP-3 in the instestine through increased of serotonin by enterochromaffin cells. PEG 4000 is one of the osmotic laxatives used to treat Opioid Induced Constipation (OIC). PEG 4000 affects the upregulation of serotonin re-uptake which can lead to expression enhancement of AQP-3. The purpose of this study was to analyze the effect of PEG 4000 on expression changes of aquaporin-3 in mice colon induced acute constipation with morphine.Constipation conditions and the effectiveness of laxative therapy are indicated by constipation parameters in the form of fecal water content and stool weight. This study used 36 male mice of the Balb/c line genus which were divided into 3 groups, normal saline, morphine, and morphine + PEG 4000. Each group was further divided into 2 subgroups based on the time of observation, namely the first hour and fifth hour after morphine induced. The expression of AQP-3 was observed using Polymerase Chain Reaction (PCR) method. The result of this study showed that the administration of PEG 4000 to mice induced constipation with morfine could decrease the expression of AQP-3 from (146,413±1,736) to (118,411±3,476) with p value <0,05, increase the percentage of fecal water content from (0,000±0,000%) to (28,903±12,930%) with p value <0,05 and increase the stool weight from (0,000±0,000g) to (0,928±0,178g) with p value <0,01 From these results, it can be concluded that the administration of PEG 4000 in morphine induced constipation to mice was effective in reducing AQP-3 expression as well as increasing the percentage of fecal water content and stool weight.
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Subratty, A. H. « Short CommunicationA Kinetic Model for In-vitro Instestinal Uptake of the Amino Acid L-tyrosine Across Rat Everted Gut Sacs ». Discovery and Innovation 15, no 1 (24 mai 2004). http://dx.doi.org/10.4314/dai.v15i1.15623.

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Hassan, Yasser Abd El Rehim, Ihab Abd Al Aziz El Shafi'I, Khaled Mohamed Abd Al Salam Al Asmar, Mohamed Hisham Ahmed et Ahmed Abd El Rahman Mousa Abd El Aziz. « Serum lactae level as an indicator for leakage in pediatric intestinal anastmosis ». QJM : An International Journal of Medicine 114, Supplement_1 (1 octobre 2021). http://dx.doi.org/10.1093/qjmed/hcab097.005.

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Abstract Background Its quite well know that high levels of serum lactic acid correlates with poor general condition and poor surgical outcome. Postoperative elevated serum lactate during the first 24h is associated with morbidity and even mortality in patients undergoing elective abdominal surgeries. In this study we need to compare the effect of fluctuation in serum lactate levels pre and postoperative on particularly instestinal anastmosis healing between elective vs emergency patients. Objective This study is designed to identify if high pre-operative lactate levels and post-operative lactate clearance are correlated with high risk of intestinal anatstmotic leakage in pediatrics. Patients and Methods This study was prospective observational study; conducted at Ain Shams University Hospital, Pediatrics surgery department and approved by the Ethical Research Committee at our hospital. We enrolled all patients (aged ≤ 14 years old) who were candidates for intestinal surgical anastomoses either elective or emergency. The patients included in our study were admitted post-operative at our department either in the intermediate or intensive care units accordingly. All patients with medical history of chronic kidney disease, liver failure, ICU admission or major surgery within the month prior to our study were excluded from our study. Results We enrolled 26 patients in our study who underwent intestinal anastomosis at our Pediatrics Surgery Department during the past six months. We had 7 female patients (26.9%) and 19 male patients (73.1%). The youngest was two-day old and the oldest was 14 years old. We had leakage incidence 38.5% of the studied patients. The cut-off lactate level for incidence of leakage is &gt; 1.2 mmol/L for the 0h (Baseline reading), &gt;2 mmol/L for the 6h, &gt;1.4mmol/L for the 12h, &gt;1.1mmol/L for the 18h, &gt;1.3mmol/L for the 24h. The highest sensitivity and specificity are for the reading at 24h that had the highest sum of both sensitivity(90%) and specificity (93.3%) and area under curve (AUC) 0.860. All patients with elevated lactate &gt; 1.4 mmol/L at 12 h had leakage (100% sensitivity) but with only 66.7% specificity. Conclusion This study shows that lactate levels during the first 24 hours postoperatively have a predictive value for postoperative intestinal anastomotic leakage after a laparotomy surgery. Serum lactate levels obtained 24 hours postoperatively had the best predictive value to discriminate between patients with and without anastomotic leakage. Although not explanatory by its design, our study demonstrates that elevated postoperative lactate is an ominous sign that should to be addressed by the intensivist. However, further studies are required to indicate which strategies aimed at resolving hyperlactatemia improve postoperative outcomes.
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