Articles de revues : « I-590 »

1

Cohen, Samuel. « The Evolution of a Disaster ». Studies in Late Antiquity 8, n^o 1 (2024) : 36–64. http://dx.doi.org/10.1525/sla.2024.8.1.36.

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This essay explores how Gregory I (bishop of Rome, 590–604) depicted two Lombard sieges of Rome, traditionally dated to 592 and 593. These events, when they are discussed, are typically presented in a litany of disasters that befell Rome at the end of the sixth century. Plague, famine, flooding, and ultimately the “swords of the Lombards” were the depressing context of Gregory’s pontificate. However, a close examination of Gregory’s letters, the principal source for Rome in this period, reveals that the bishop’s presentation of these Lombard attacks evolved considerably between 591 and 595. Indeed, it was only in response to several controversies with the East, including criticisms by the exarch Romanus and especially the use of the title universalis episcopus (typically translated into English as ecumenical patriarch) by Patriarch John IV of Constantinople (582–95), that Gregory came to recast the Lombard campaigns as disasters for Rome and the causes of great suffering. Rome’s suffering then served as a rhetorical foil against which Gregory contrasted what he saw as the callous neglect of imperial officials and especially John’s prideful asceticism performed in the safety of Constantinople.

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Мигальников, Алексей Владимирович. « Апелляция малоазийских клириков к папе Григорию Великому : ход дела и вопрос о его каноничности ». Византийский временник = ΒΥΖΑΝΤΙΝΑ ΧΡΟΝΙΚΑ, n^o 107, 2023 (2024) : 93–113. http://dx.doi.org/10.55959/msu0132-3776-2024-107-93-113.

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Статья посвящена рассмотрению судебных дел двух малоазийских клириков, обвиненных в ереси приговором Константинопольского патриарха таи подавших апелляцию папе Григорию I (590-604). Подробно разобран ход самих дел, а также вопрос о формальной каноничности действий папы Григория, посчитавшего возможным принять апелляции клириков и пересмотреть их приговоры. Выдвигается гипотеза о том, по каким причинам Константинопольские патриархи Иоанн IV Постник (582-595) и Кириак II (595-606) не высказали возражений против перевода судебных дел в папскую юрисдикцию.

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Мигальников, Алексей Владимирович. « Апелляция малоазийских клириков к папе Григорию Великому : ход дела и вопрос о его каноничности ». Византийский временник = ΒΥΖΑΝΤΙΝΑ ΧΡΟΝΙΚΑ, n^o 107, 2023 (2024) : 93–113. http://dx.doi.org/10.55959/msu0132-3776-2023-107-93-113.

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Статья посвящена рассмотрению судебных дел двух малоазийских клириков, обвиненных в ереси приговором Константинопольского патриарха таи подавших апелляцию папе Григорию I (590-604). Подробно разобран ход самих дел, а также вопрос о формальной каноничности действий папы Григория, посчитавшего возможным принять апелляции клириков и пересмотреть их приговоры. Выдвигается гипотеза о том, по каким причинам Константинопольские патриархи Иоанн IV Постник (582-595) и Кириак II (595-606) не высказали возражений против перевода судебных дел в папскую юрисдикцию.

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Zhou, Yaqin, Zhangchuan Xia, Zhikui Cheng, Gang Xu, Xiaodan Yang, Shi Liu et Ying Zhu. « Inducible microRNA-590-5p inhibits host antiviral response by targeting the soluble interleukin-6 (IL6) receptor ». Journal of Biological Chemistry 293, n^o 47 (5 octobre 2018) : 18168–79. http://dx.doi.org/10.1074/jbc.ra118.005057.

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MicroRNA (miR)-590-5p has been identified as an important regulator of some signaling pathways such as cell proliferation and tumorigenesis. However, little is known about its role during viral infection. Here, we report that miR-590-5p was significantly induced by various viruses and effectively potentiated virus replication in different viral infection systems. Furthermore, miR-590-5p substantially attenuated the virus-induced expression of type I and type III interferons (IFNs) and inflammatory cytokines, resulting in impaired downstream antiviral signaling. Interleukin-6 receptor (IL6R) was identified as a target of miR-590-5p. Interestingly, the role of miR-590-5p in virus-triggered signaling was abolished in IL6R knockout cells, and this could be rescued by restoring the expression of the soluble IL6R (sIL6R) but not the membrane-bound IL6R (mIL6R), suggesting that sIL6R is indispensable for miR-590-5p in modulating the host antiviral response. Furthermore, miR-590-5p down-regulated endogenous sIL6R and mIL6R expression through a translational repression mechanism. These findings thus uncover a previously uncharacterized role and the underlying mechanism of miR-590-5p in the innate immune response to viral infection.

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Chen, Yinan, Changhui Sun, Jiong Lu, Ling Zou, Minwei Hu, Zeyu Yang et Yaozeng Xu. « MicroRNA-590-5p antagonizes the inhibitory effect of high glucose on osteoblast differentiation by suppressing Smad7 in MC3T3-E1 cells ». Journal of International Medical Research 47, n^o 4 (26 février 2019) : 1740–48. http://dx.doi.org/10.1177/0300060519830212.

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Objective MicroRNA-590-5p (miR-590-5p) has been reported to stimulate osteoblast differentiation; however, its effect in diabetic osteoporosis remains unknown. This study investigated the effect of miR-590-5p on high glucose (HG)-suppressed osteoblast differentiation. Methods The effect of HG on MC3T3-E1 cell survival was assessed using the MTT assay. The expression levels and activities of osteoblastic proteins were evaluated by quantitative reverse transcription polymerase chain reaction (qRT-PCR), alkaline phosphatase (ALP) assay, and immunoblotting assay. Tumor growth factor-β (TGF-β) signaling in MC3T3-E1 cells was assessed using luciferase assay, qRT-PCR, and immunoblotting. Mineralized nodule formation in MC3T3-E1 cells was examined by using the mineralization assay. Results When MC3T3-E1 cells were exposed to HG conditions, there was significant downregulation of miR-590-5p and osteoblastic proteins (e.g., collagen I, Runx2, and ALP); in contrast, Smad7 was upregulated. Furthermore, miR-590-5p targeted Smad7 and inhibited its expression. Additionally, overexpression of miR-590-5p significantly promoted osteoblast growth and differentiation by upregulating TGF-β signaling in HG-treated MC3T3-E1 cells. Conclusions Collectively, the results showed that miR-590-5p was involved in osteogenesis; moreover, miR-590-5p may represent a potential target for the treatment of diabetic osteoporosis.

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ZYGNER, WOJCIECH, PIOTR BĄSKA, MARCIN WIŚNIEWSKI et HALINA WĘDRYCHOWICZ. « The Molecular Evidence of Babesia microti in Hard Tics Removed from Dogs in Warsaw (Central Poland) ». Polish Journal of Microbiology 59, n^o 2 (2010) : 95–97. http://dx.doi.org/10.33073/pjm-2010-014.

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The purpose of this study was to specify the occurrence and prevalence of Babesia microti in hard ticks removed from dogs in Warsaw (central Poland). Among 590 collected ticks, 209 were identified as Ixodes ricinus, and 381 as Dermacentor reticulatus. B. microti DNA was detected in 11 out of 590 (1.86%) samples of ticks. The DNA of the parasite was detected only in lysates from female I. ricinus ticks (11 out of 193; 5.7%). The result of this study is the first evidence of B. microti in I. ricinus ticks in Warsaw.

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Romero Mensaque, Carlos. « Constituciones conciliares y sinodales del Arzobispado de Sevilla (I) = Conciliars and synodals Constitutions of the Archbishopric of Seville (I) ». Revista de Humanidades, n^o 33 (9 janvier 2018) : 197. http://dx.doi.org/10.5944/rdh.33.2018.20811.

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Reseña de la obra / Book review: Sánchez Herrero, J. (dir.) (2007). Synodicon Baeticum I. Constituciones conciliares y sinodales del Arzobispado de Sevilla. Tomo I: años 590 al 1604. Sevilla: Universidad de Sevilla, 187 p. + 1 CD. ISBN 978-84-472-0940-8.

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Zhao, Xiaojuan, Fengxia Li, Qingyan Zhang, Zengbo Li, Yehong Zhou, Jun Yang, Chuan Dong, Junping Wang et Shaomin Shuang. « Mn-doped ZnS quantum dots with a 3-mercaptopropionic acid assembly as a ratiometric fluorescence probe for the determination of curcumin ». RSC Advances 5, n^o 28 (2015) : 21504–10. http://dx.doi.org/10.1039/c5ra01412c.

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Mn-doped ZnS quantum dots capped with 3-mercaptopropionic acid (MPA) were synthesized by a facile method in aqueous solution as a ratiometric fluorescent (I_{590 nm}/I_{458 nm}) probe for curcumin.

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BANNON, G., J. STANLEY, G. COCKRELL, R. HELM, H. SAMPSON et A. BURKS. « 590 Peanut allergen Ara h I : Identifying the clinically relevant epitopes ». Journal of Allergy and Clinical Immunology 97, n^o 1 (janvier 1996) : 330. http://dx.doi.org/10.1016/s0091-6749(96)80808-6.

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Żebrowska, Jadwiga, et Agata Pacek. « Influence of plasmogenes on the productivity of morphogenesis in strawberry (Fragaria x ananassa Duch.) ». Acta Agrobotanica 61, n^o 2 (2012) : 3–10. http://dx.doi.org/10.5586/aa.2008.028.

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Plasmogenes are largely located in mitochondria or plastids and they can influence the inheritance of many plant characteristics. This phenomenon is called cytoplasmic inheritance and can be detected on the basis of the expression of a trait in progeny F1 obtained from single and reciprocal crosses. The aim of this study was to examine the cytoplasmic inheritance of in vitro productivity of morphogenesis in three genotypes of Fragaria x ananassa Duch., i.e. the cultivars 'Dukat', 'Teresa' and the breeding clone no. 590. Single and reciprocal crosses were done according to Griffi ng's method 3. The value of general combining ability (GCA) indicated cv. 'Teresa' as the best maternal component for crossing and 'Dukat' as the worst. The negative reciprocal cross effects (rij) revealed the cytoplasmic inheritance for cv. 'Dukat' as maternal form and positive rij for the breeding clone no. 590 indicated the nuclear inheritance of morphogenetic ability. Cv. 'Teresa', as maternal component, showed nuclear inheritance of that trait in crossing with cv. 'Dukat' and with 590 cytoplasmic inheritance. The productivity of morphogenesis in strawberry depended on the parental combination and the direction of crossing.

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Lee, Hye-Min. « Images and Experiences of the Plague of Rome during the Time of Gregory I ». Korea Association of World History and Culture 68 (30 septembre 2023) : 189–217. http://dx.doi.org/10.32961/jwhc.2023.09.68.189.

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In the year 590, when a devastating plague swept through Rome, Pope Gregory I endeavored to uplift and support the Roman population. The most significant primary source that provides invaluable insights into this historical event is The Histories of Gregory of Tours. He vividly portrays the stunning disasters of inundation and plague that occurred in Rome in 590, overlaying them with apocalyptic imagery. This paper argues that it is necessary to understand Gregory of Tours’ writing from the perspective of disaster narratives specific to medieval historical writing. Furthermore, The Dialogues of Pope Gregory I is another source that allows us to glimpse the experiences of pestilence in Rome. It contains accounts of the victims who endured this catastrophic epidemic. Notably, it presents the figure of Death not only as dragon but also as Moors who appear to claim a dying person’s soul. This paper undertakes a re-examination of these primary sources in order to gain insight into how people perceived and experienced the plague and death during the end of the 6th century.

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Iwaszkiewicz-Wronikowska, Bożena. « Świeccy jako fundatorzy kościelnych budowli w Rzymie wczesnochrześcijańskim ». Vox Patrum 42 (15 janvier 2003) : 339–53. http://dx.doi.org/10.31743/vp.7164.

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Nella seconda meta del V s. i vescovi mostrarono una sempre maggiore inclinazione a ridurre l'influenza dei donatori ai funzionamento delle fondazioni. Le regolazioni legali di Pelagio (556-561) e di Gregorio Magno (590-604) portarono ad un effettivo controllo dei vescovi sopra le fondazioni dei laici. Nel VI s. i laici a Roma partecipano sempre meno nelle fondazioni; cominciano a dominare quelle pontificie, specialmente nel campo dedicato alla carita.

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Wunder, Gerd, et Johannes Müllner. « Rezension von : Müllner, Johannes, Von den Anfängen bis 1350 ... » Württembergisch Franken 70 (20 novembre 2023) : 209–10. http://dx.doi.org/10.53458/wfr.v70i.8597.

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Johannes Müllner: Die Annalen der Reichsstadt Nürnberg von 1623. Hrsg. von Gerhard Hirschmann:Teil I: Von den Anfängen bis 1350. (= Quellen zur Geschichte und Kultur der Stadt Nürnberg, 8). Nürnberg 1972. 590 S.Teil II: Von 1351 bis 1469. (= Quellen zur Geschichte und Kultur der Stadt Nürnberg, 11). Nürnberg 1984. 663 S.

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Alekseev, P. V., M. V. Demin et V. N. Kuznetsov. « I. T. Frolov, ed. Philosophical Dictionary, 5th ed. (Moscow : Politizdat, 1986, 590 pp.) ». Soviet Studies in Philosophy 27, n^o 2 (octobre 1988) : 80–91. http://dx.doi.org/10.2753/rsp1061-1967270280.

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Paulo Charrone, João. « O USO PEDAGÓGICO DAS IMAGENS NA CORRESPONDÊNCIA PAPAL DE GREGÓRIO I (590-604) ». Labirinto 30, n^o 1 (2019) : 26–38. http://dx.doi.org/10.47209/1519-6674.v30.n.1.p.26-38.

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WESTERN, JOSEPH. « The Papal Apocrisiarii in Constantinople during the Pontificate of Gregory i, 590–604 ». Journal of Ecclesiastical History 66, n^o 4 (2 septembre 2015) : 697–714. http://dx.doi.org/10.1017/s0022046915001621.

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From the fifth through to the eighth century an ecclesiastical official, the apocrisiarius, streamlined the effective governance of both Church and Empire by serving as the pope's permanent representative at the imperial Byzantine court. The letters of a former apocrisiarius, Pope Gregory i, serve as the best sources for uncovering the duties of this office and its benefits to the Church and the Empire. Investigating this office under Gregory emphasises the independent ambassadorial mandate given to these men and highlights the vital role of personal relationships in the conduct of imperial business.

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Fieiel, Chester R. « Crayfish population genetic studies : assessment and trends ». Freshwater Crayfish 22, n^o 1 (31 décembre 2016) : 19–42. http://dx.doi.org/10.5869/fc.2016.v22-1.17.

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Abstract I surveyed the peer-reviewed literature for studies on crayfish population genetics over the last 20 years (1996 to 2015). My objectives were to determine if there is research disparities based on crayfish conservation status, ecological group, geographic location, and genetic methods used. Additionally, I wished to determine overall trends in crayfish genetics related to population variability, systematics, and technique development. An extensive literature search yielded 201 peer-reviewed articles with genetic information published on 335 of the 590 crayfish species found worldwide. The majority of peer-reviewed articles took place in Europe and Australia/Oceania despite the fact that crayfish biodiversity is greatest in North America. Crayfish within each ecological group (primary burrowers, lotic inhabitants, lentic inhabitants, and stygobitic species) are represented in these published papers. I found published articles on ~ 57% of the estimated 590 extant species. Further, of the 173 species listed as critically endangered, endangered, vulnerable, or as near threatened by the International Union for Conservation of Nature, I found published research on ~ 62% of these species in these classifications thus indicating a knowledge gap for many imperiled species. This lack of basic genetic (and ecological) information is significant as species designation is often used to determine where we should focus our conservation actions. Understanding what constitutes a single interbreeding population and identifying taxonomic designations are priorities for defining conservation management plans.

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Figiel, Chester R. « Crayfish population genetic studies : assessment and trends ». Freshwater Crayfish 22, n^o 1 (31 décembre 2016) : 19–42. http://dx.doi.org/10.5869/fc.2016.v22-1.19.

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Abstract I surveyed the peer-reviewed literature for studies on crayfish population genetics over the last 20 years (1996 to 2015). My objectives were to determine if there is research disparities based on crayfish conservation status, ecological group, geographic location, and genetic methods used. Additionally, I wished to determine overall trends in crayfish genetics related to population variability, systematics, and technique development. An extensive literature search yielded 201 peer-reviewed articles with genetic information published on 335 of the 590 crayfish species found worldwide. The majority of peer-reviewed articles took place in Europe and Australia/Oceania despite the fact that crayfish biodiversity is greatest in North America. Crayfish within each ecological group (primary burrowers, lotic inhabitants, lentic inhabitants, and stygobitic species) are represented in these published papers. I found published articles on ~ 57% of the estimated 590 extant species. Further, of the 173 species listed as critically endangered, endangered, vulnerable, or as near threatened by the International Union for Conservation of Nature, I found published research on ~ 62% of these species in these classifications thus indicating a knowledge gap for many imperiled species. This lack of basic genetic (and ecological) information is significant as species designation is often used to determine where we should focus our conservation actions. Understanding what constitutes a single interbreeding population and identifying taxonomic designations are priorities for defining conservation management plans.

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Tulyakova, M. V., G. A. Batalova et S. V. Permyakova. « Adaptive potential of the hulled oats gene pool according to 1000-grain weight ». Grain Economy of Russia, n^o 5 (28 octobre 2021) : 3–8. http://dx.doi.org/10.31367/2079-8725-2021-77-5-3-8.

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There have been presented the study results of 11 collection hulled oats samples in comparison with the standard variety ‘Krechet’ conducted at the Falenskaya selection station of the FARC the North-East (the Kirov region) in 2018–2020. The purpose of the current study was to identify sources stable on the trait ‘1000-grain weight’ for the breeding of hulled oats by estimating the adaptability parameters. The soil of the experimental plot was sod-podzolic, medium loamy, the meteorological conditions were contrasting in temperature and precipitation. In the favorable year of 2019, the 1000-grain weight was the highest (34.6–45.9 g), the index of environmental conditions was positive (Ij = 1.6). In the unfavorable year of 2020, the 1000-grain weight was 31.3–41.8 g and the index of environmental conditions was negative (Ij = -1.5). There have been identified the adaptable sources (IEP = 1.08–1.00) ‘15330 KSI 590/05’ (Russia), ‘15388 Saltaret’ (Moldova), ‘15423 Prelekst’, ‘15426 Werva’ (Germany); the stable sources according to the relative stability of the trait (St2 = 0.99–0.91) ‘15280 55 h 2106’, ‘15331 CSI 2167/03’ (Russia), ‘15297 Geszti’ (Hungary), ‘15388 Saltaret’ (Moldova), ‘15428 Bohum’ (Poland), ‘15420 Leniak’ (Germany); the sources with a high level of intensity (I = 24.5 and 19.30%) – ‘15329 CSI 639/05’, ‘15330 CSI 590/05’ and homeostaticity (Hom = 25.28–11.96) ‘15280 55 h 2106’ (Russia), ‘15297 Geszti’ (Hungary), ‘15388 Saltaret’ (Moldova); the sources responsive to favorable growing conditions (Kp = 1.11–1.28) ‘15329 KSI 639/05’, ‘15330 KSI 590/05’, ‘15331 KSI 2167/03’ (Russia), ‘15414 Enostar’ (Germany); the most adaptive sources in terms of the sum of ranks ‘15330 CSI 590/05’ and ‘15329 CSI 639/05’ (Russia), ‘15388 Saltaret’ (Moldova), ‘15426 Werva, ‘15414 Enostar’ (Germany). There have been identified significant direct correlations between indicators of stability and homeostaticity (r = 0.96), intensity and coefficient of responsiveness (r = 0.73).

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Zenkin, N., A. Kulbachinskiy, I. Bass et V. Nikiforov. « Different Rifampin Sensitivities of Escherichia coli and Mycobacterium tuberculosis RNA Polymerases Are Not Explained by the Difference in the β-Subunit Rifampin Regions I and II ». Antimicrobial Agents and Chemotherapy 49, n^o 4 (avril 2005) : 1587–90. http://dx.doi.org/10.1128/aac.49.4.1587-1590.2005.

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ABSTRACT Mycobacterium tuberculosis RNA polymerase is 1,000-fold more sensitive to rifampin than Escherichia coli RNA polymerase. Chimeric E. coli RNA polymerase in which the β-subunit segment encompassing rifampin regions I and II (amino acids [aa] 463 through 590) was replaced with the corresponding region from M. tuberculosis (aa 382 through 509) did not show an increased sensitivity to the antibiotic. Thus, the difference in amino acid sequence between the rifampin regions I and II of the two species does not account for the difference in rifampin sensitivity of the two polymerases.

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Liang, Rui, Leon Shterengas, Gela Kipshidze, Takashi Hosoda, Sergey Suchalkin et Gregory Belenky. « Novel Cascade Diode Lasers Based on Type-I Quantum Wells ». International Journal of High Speed Electronics and Systems 23, n^o 03n04 (septembre 2014) : 1450022. http://dx.doi.org/10.1142/s0129156414500220.

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A novel approach for cascade diode lasers was developed based on type-I quantum wells (QWs). This design adopted the leaky window effect in the GaSb / InAs band alignment for cascade pumping, and exploits the carriers recycling by the cascade pumping and the high optical gain of the type-I QWs. Two-stage cascade lasers were designed and fabricated for 2.45 and 3.0 μm, demonstrating twofold improvement in the internal efficiency. Record continuous-wave (CW) output power of 1.2 W for 2.45 um and 590 mW for 3.0 um were achieved in room temperature (RT), and the devices operate with higher power conversion efficiency at high power level, compared to conventional single-stage diode lasers.

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Zadro, Ana, et Goran Mijočević. « Srednjovjekovni motivi na poštanskim markama Hrvatske pošte Mostar u kulturi sjećanja ». Hercegovina. Serija 3 : časopis za kulturno i povijesno nasljeđe, n^o 8 (22 septembre 2022) : 53–82. http://dx.doi.org/10.47960/2712-1844.2022.8.53.

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Autori u radu analiziraju ulogu poštanskih maraka sa srednjovjekovnim motivima u kulturi kolektivnoga sjećanja. Analiza obuhvaća marke koje su objavljene u nakladi Hrvatske pošte Mostar u razdoblju od 1993. do kraja 2021. godine. Od ukupno 590 poštanskih maraka koje je HP Mostar objavila (kao redovne i prigodne) 32 su sa srednjovjekovnim motivom ili nazivom. U radu se ne posvećuje pažnja analizi slikovnoga prikaza, odnosno idejnoga rješenja slikovnoga motiva na samoj poštanskoj marki, nego se bavi pitanjem važnosti toga motiva (osoba, mjesto, događaj, spomenik i slično) za kolektivni identitet zajednice. Ključne riječi: poštanske marke; filatelija; srednjovjekovni motivi; kultura sjećanja; povijest.

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Kohút, Milan, Pavel Uher, Marián Putiš, Martin Ondrejka, Sergey Sergeev, Alexander Larionov et Ilya Paderin. « SHRIMP U-Th-Pb zircon dating of the granitoid massifs in the Malé Karpaty Mountains (Western Carpathians) : evidence of Meso-Hercynian successive S- to I-type granitic magmatism ». Geologica Carpathica 60, n^o 5 (1 octobre 2009) : 345–50. http://dx.doi.org/10.2478/v10096-009-0026-z.

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SHRIMP U-Th-Pb zircon dating of the granitoid massifs in the Malé Karpaty Mountains (Western Carpathians): evidence of Meso-Hercynian successive S- to I-type granitic magmatismRepresentative granitic rock samples from the Malé Karpaty Mountains of the Western Carpathians (Slovakia) were dated by the SHRIMP U-Th-Pb isotope method on zircons. Oscillatory zoned zircons revealed concordant Mississippian magmatic ages: 355±5 Ma in Bratislava granodiorite, and 347±4 Ma in Modra tonalite. The results document nearly synchronous, successive Meso-Hercynian plutonic events from S-type to I-type granites. The Neo-Proterozoic inherited zircon cores (590±13 Ma) were identified in the Bratislava S-type granitic rocks whereas scarce Paleo-Proterozoic inherited zircons (1984±36 Ma) were detected within the Modra I-type tonalites.

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Gusain, Manju Prakash, Bhaskranand Semalty, Jitendra Singh Rana, Anupama Negi, Lakhpat Singh et O. P. Gusain. « Riffles inhabiting benthic macroinvertebrate communities in a spring• fed tributary of River Alaknanda (Garhwal Himalaya) ». Environment Conservation Journal 10, n^o 1&2 (16 juin 2009) : 171–78. http://dx.doi.org/10.36953/ecj.2009.101230.

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Bachchan Gad is a spring-fed tributary of River Alaknanda in the Garhwal region of Uttarakhand. Benthic macroinvertebrates in the riffles of Bachchan Gad was investigated during March 2008 to February 2009 at four sampling sites between 590 m tol600 m above sea level. Pre I iminary observations revealed that riffle inhabiting benthic macroinvertebrates communities in the Bachchan Gad comprised of 36 insect genera belonging to 8 orders and 29 families along with I genus each of crustacean and annelida. Dominated by Ephemeropteran, Trichopteran and Co/eopteran genera the density was highest (1300±142 Individual m?) during winter at confluence, the downstream site, it was recorded lowest (80± 15.2 Individual m) during monsoon at Pata, the headwater site.

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Latham, Jacob A. « Inventing Gregory “the Great” : Memory, Authority, and the Afterlives of the Letania Septiformis ». Church History 84, n^o 1 (mars 2015) : 1–31. http://dx.doi.org/10.1017/s0009640714001693.

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In modern scholarship, Pope Gregory I “the Great” (590–604) is often simultaneously considered the final scion of classical Rome and the first medieval pope. The letania septiformis, a procession organized into seven groups that Gregory instituted in 590 in the face of plague and disease (and performed only once thereafter in 603), has similarly been construed as the very moment when Antiquity died and the Middle Ages were born. However, his Roman contemporaries in the papal curia largely ignored Gregory and his purportedly epochal procession. In fact, memory of the procession languished in Italy until the late-eighth century when Paul the Deacon made it the center of his Life of Gregory. At Rome, remembrance of the procession lay dormant in the papal archives until John the Deacon dug it out in the late-ninth century. How then did the letania septiformis come to be judged so pivotal? Over the course of centuries, the letania septiformis was inventively re-elaborated in literature, liturgy, and legend as part of the re-fashioning of the memory of Gregory. Shorn of its context, the letania septiformis gained greater imaginative power, becoming the emblem of Gregory's pontificate, if not also of an historical era.

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Yang, Jaewan. « Leveraging leader–leader exchange to enrich the effect of leader–member exchange on team innovation ». Journal of Management & ; Organization 26, n^o 4 (25 octobre 2017) : 555–70. http://dx.doi.org/10.1017/jmo.2017.54.

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AbstractIn this study, I propose supervisors’ upward leader–leader exchange relationships as an important boundary condition for the relationship between average leader–member exchange (LMX) relationships and a climate for innovation support at the group level. Specifically, I argue that the effect of resource spillover to poor-LMX subordinates within a work group is an important mechanism that leads to the development of a climate that supports innovation. I test the hypothesized moderated-mediation model by using multisource and multiwave data collected from 590 employees and 75 supervisors. The findings indicate that the indirect effect of team LMX relationships on team effectiveness via a climate for innovation support is more positive under high conditions of leader–leader exchange, whereas the effect is less positive under low conditions of leader–leader exchange. Implications and limitations relevant to developing research around LMX and innovation are addressed.

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Cato, A. C., E. Heitlinger, H. Ponta, L. Klein-Hitpass, G. U. Ryffel, A. Bailly, C. Rauch et E. Milgrom. « Estrogen and progesterone receptor-binding sites on the chicken vitellogenin II gene : synergism of steroid hormone action ». Molecular and Cellular Biology 8, n^o 12 (décembre 1988) : 5323–30. http://dx.doi.org/10.1128/mcb.8.12.5323-5330.1988.

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The chicken vitellogenin II gene is transcriptionally activated by estrogens. In transient transfection experiments in human T47D cells that contain receptors for various steroids, we showed estradiol, progestin, and androgen responses of a chimeric chicken vitellogenin II construct. This construct consists of DNA sequences from -626 to -590 upstream of the start of transcription of the chicken vitellogenin gene linked to the herpes simplex virus thymidine kinase promoter driving the transcription of the bacterial chloramphenicol acetyltransferase gene. Treatment of the transfected T47D cells with a combination of estradiol and the progestin R5020 led to a superinduction of chloramphenicol acetyltransferase activity, showing a synergistic action of these two steroids. This synergism was not observed upon treatment of the transfected cells with estradiol and the androgen dihydrotestosterone. Using point mutations in the vitellogenin gene fragment, we showed in functional and in in vitro DNase I footprinting assays with a purified progesterone receptor that, for the synergistic action of estradiol and R5020 to occur, the progesterone receptor must be bound to the vitellogenin gene fragment. The progesterone receptor-binding site was localized at -610 to -590, close to the consensus sequence (-626 to -613) for estrogen receptor binding and function. We therefore demonstrate here that two different steroid hormones can be functionally synergistic through the interaction of their corresponding receptors with two different binding sites adjacent to one another.

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Cato, A. C., E. Heitlinger, H. Ponta, L. Klein-Hitpass, G. U. Ryffel, A. Bailly, C. Rauch et E. Milgrom. « Estrogen and progesterone receptor-binding sites on the chicken vitellogenin II gene : synergism of steroid hormone action. » Molecular and Cellular Biology 8, n^o 12 (décembre 1988) : 5323–30. http://dx.doi.org/10.1128/mcb.8.12.5323.

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The chicken vitellogenin II gene is transcriptionally activated by estrogens. In transient transfection experiments in human T47D cells that contain receptors for various steroids, we showed estradiol, progestin, and androgen responses of a chimeric chicken vitellogenin II construct. This construct consists of DNA sequences from -626 to -590 upstream of the start of transcription of the chicken vitellogenin gene linked to the herpes simplex virus thymidine kinase promoter driving the transcription of the bacterial chloramphenicol acetyltransferase gene. Treatment of the transfected T47D cells with a combination of estradiol and the progestin R5020 led to a superinduction of chloramphenicol acetyltransferase activity, showing a synergistic action of these two steroids. This synergism was not observed upon treatment of the transfected cells with estradiol and the androgen dihydrotestosterone. Using point mutations in the vitellogenin gene fragment, we showed in functional and in in vitro DNase I footprinting assays with a purified progesterone receptor that, for the synergistic action of estradiol and R5020 to occur, the progesterone receptor must be bound to the vitellogenin gene fragment. The progesterone receptor-binding site was localized at -610 to -590, close to the consensus sequence (-626 to -613) for estrogen receptor binding and function. We therefore demonstrate here that two different steroid hormones can be functionally synergistic through the interaction of their corresponding receptors with two different binding sites adjacent to one another.

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Vais, Ram Ishwar, Kuldeep Sahay, Tirumalasetty Chiranjeevi, Ramesh Devarapalli et Łukasz Knypiński. « Crystal Symmetry-Inspired Algorithm for Optimal Design of Contemporary Mono Passivated Emitter and Rear Cell Solar Photovoltaic Modules ». Algorithms 17, n^o 7 (6 juillet 2024) : 297. http://dx.doi.org/10.3390/a17070297.

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A metaheuristic algorithm named the Crystal Structure Algorithm (CrSA), which is inspired by the symmetric arrangement of atoms, molecules, or ions in crystalline minerals, has been used for the accurate modeling of Mono Passivated Emitter and Rear Cell (PERC) WSMD-545 and CS7L-590 MS solar photovoltaic (PV) modules. The suggested algorithm is a concise and parameter-free approach that does not need the identification of any intrinsic parameter during the optimization stage. It is based on crystal structure generation by combining the basis and lattice point. The proposed algorithm is adopted to minimize the sum of the squares of the errors at the maximum power point, as well as the short circuit and open circuit points. Several runs are carried out to examine the V-I characteristics of the PV panels under consideration and the nature of the derived parameters. The parameters generated by the proposed technique offer the lowest error over several executions, indicating that it should be implemented in the present scenario. To validate the performance of the proposed approach, convergence curves of Mono PERC WSMD-545 and CS7L-590 MS PV modules obtained using the CrSA are compared with the convergence curves obtained using the recent optimization algorithms (OAs) in the literature. It has been observed that the proposed approach exhibited the fastest rate of convergence on each of the PV panels.

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Seo, Hyejun, Soyoung Park, Eungyung Lee, Taesung Jeong et Jonghyun Shin. « Survival Rates of Class II Restoration in Primary Molar with Flowable Resin Composite ». JOURNAL OF THE KOREAN ACADEMY OF PEDTATRIC DENTISTRY 48, n^o 1 (28 février 2021) : 12–20. http://dx.doi.org/10.5933/jkapd.2021.48.1.12.

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The purpose of this retrospective study was to evaluate the survival rate by comparing Class II restoration using flowable resin composite with stainless steel crown in primary molars. Electronic medical records and radiographs of 1,504 primary molars with proximal caries of 590 patients from June 2015 to August 2019 were analyzed. With the collected data, survival analysis was performed using the Kaplan-Meier method. The 1-year survival rate of flowable resin composite in the primary molar was 98.5%, 3-year survival rate was 87.7%, and mean survival time was 39 months. There was no statistically significant difference between flowable resin composite and stainless steel crown (p = 0.896). Within the limits of this study, Class II restoration using flowable resin composite can be considered a promising option for the treatment of proximal caries in primary molars.

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IANNACCONE, ISAIA. « DOCUMENTS RELATIFS L'HISTOIRE DE L'ASTRONOMIE CHINOISE ET AUX RAPPORTS SCIENTIFIQUES ENTRE L'EUROPE ET LA CHINE (XVIIE-XIXE SICLES) CONSERVS LA BIBLIOTHQUE DE L'OBSERVATOIRE DE PARIS ». Nuncius 15, n^o 1 (2000) : 325–64. http://dx.doi.org/10.1163/182539100x00515.

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Abstracttitle RIASSUNTO /title Nella biblioteca dell'Osservatorio Astronomico di Parigi sono conservati numerosi documenti d'epoca, relativi ai rapporti scientifici Europa-Cina tra i secoli XVII-XIX. Tra essi, corrispondenze, carte, opere, note e osservazioni astronomiche di scienziati gesuiti missionari in Cina, quali A. Gaubil (1689-1759), F. Verbiest (1623-1688), I. Kgler (1680-1746), ecc., traduzioni di testi cinesi, tra cui spicca una copia sei-settecentesca del Bu Tian Ge (Poesie sui movimenti del cielo, circa 590 d.C.) tradotta e commentata da A. Gaubil. L'interesse dei documenti investe non soltanto il campo astronomico, ma anche quelli geografico, antropologico, linguistico, di costume, ecc., ed essi sono indispensabili per lo studio comparato dell'evoluzione scientifica in Europa e in Cina, e per la conoscenza storica in generale. L'articolo si prefigge di recuperare, analizzare, mettere in valore e presentare in modo sistematico questo patrimonio di documenti.

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Szkody, Paula. « Time-resolved IUE studies of cataclysmic variables. I - Eclipsing systems IP Peg, PG 1030+590, and V1315 AQL ». Astronomical Journal 94 (octobre 1987) : 1055. http://dx.doi.org/10.1086/114540.

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Armendariz-Borunda, J., C. P. Simkevich, N. Roy, R. Raghow, A. H. Kang et J. M. Seyer. « Activation of Ito cells involves regulation of AP-1 binding proteins and induction of type I collagen gene expression ». Biochemical Journal 304, n^o 3 (15 décembre 1994) : 817–24. http://dx.doi.org/10.1042/bj3040817.

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Activation of liver Ito cells is characterized by increased proliferation, fibrogenesis, loss of cellular retinoid and change of cell-shape. Here, we have described fundamental differences between freshly isolated Ito cells (FIC) and long-term cultured Ito cells (LTIC). This process of activation correlates with the absence of expression of Pro alpha 1(I) gene in FIC. LTIC expressed abundant transcripts of Pro alpha 1(I) gene. Nuclear run-off experiments showed the inability of FIC to support Pro alpha 1(I) RNA transcription while LTIC transcribed it greater than 5-fold as compared with FIC. Transforming growth factor beta (TGF beta)-treated LTIC had a preferential increase in the rate of Pro alpha 1(I) gene transcription as compared with control LTIC. A human collagen type I promoter-enhancer construct (pCOL-KT) [Thompson, Simkevich, Holness, Kang and Raghow (1991) J. Biol. Chem. 266, 2549-2556] was readily expressed in LTIC but failed to be expressed in FIC. Furthermore, TGF beta treatment of LTIC resulted in an increased expression of pCOL-KT. The deletion of an activator protein-1 (AP-1) binding site (+598 to +604) in the 360 bp enhancer region of pCOL-KT (S360) caused decreased expression of the CAT reporter gene, suggesting that this bonafide AP-1 site can, at least in part, mediate the transactivation effect of TGF beta. Using DNAase I protection, we demonstrate a single foot-print located at +590 to +625 in the S360 fragment; nuclear extracts prepared from TGF beta-treated LTIC exhibited greater activity of these AP-1 binding proteins. Gel mobility assays corroborated and extended the footprinting observation. No AP-1-binding activity was found in the nuclear extracts of FIC. Double-stranded oligonucleotides containing the consensus AP-1 motif were able to compete out the binding; consensus NF-1 motif oligonucleotides failed to do so. The preincubation of nuclear extracts from control and TGF beta-treated LTIC with antibodies against c-jun and c-fos rendered a reduced binding of AP-1 proteins to the target S360 fragment.

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Fernández-Tornero, Carlos. « Crystal structure of RNA polymerase I ». Acta Crystallographica Section A Foundations and Advances 70, a1 (5 août 2014) : C1391. http://dx.doi.org/10.1107/s2053273314086082.

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In eukaryotes ribosome biosynthesis starts with ribosomal RNA production by RNA polymerase I (Pol I), a process that is critical to regulate cell growth and proliferation. We were able to obtain the crystal structure of yeast Pol I, a 14-subunit complex with a total mass of 590 kDa, at 3.0 Å resolution [1]. The current communication deals with the functional implications of this beautiful structure, while details on structure determination will be presented by Tim Gruene at this meeting. The structure represents the latent state of the enzyme, characterized by three major features. First, it forms dimers that involve the C-terminal tail of the stalk subunit A43. Second, the two enzyme halves pivot along the DNA-binding cleft to produce an open cleft and an unfolded bridge helix. Third, an extended loop in subunit A190 mimics the DNA backbone along the cleft, hampering nucleic acid binding. All three features must be resolved during enzyme activation. The Pol I crystal structure also reveals intrinsic modules that only bind transiently in other RNA polymerases. Subunit A12.2 inserts a TFIIS-like zinc ribbon into the active site, providing insight into its role in RNA cleavage and Pol I insensitivity to α-amanitin. The A49-A34.5 heterodimer binds the outer side of subunit A135 through a TFIIF-like dimerization module, suggesting how it may function during transcriptional initiation and elongation.

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Rahmawati, Nuari, et Anggun Resdasari Prasetyo. « HUBUNGAN ANTARA IKLIM ORGANISASI DENGAN KOMITMEN ORGANISASI PADA PETUGAS PEMASYARAKATAN KELAS I SEMARANG ». Jurnal EMPATI 6, n^o 1 (16 janvier 2017) : 317–21. http://dx.doi.org/10.14710/empati.2017.15131.

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Komitmen organisasi merupakan suatu sikap yang membuat individu sebagai anggota organisasi memiliki hasrat untuk bertahan dalam organisasi, loyal terhadap organisasi, dan keinginan untuk terlibat dalam pekerjaan. Lingkungan kerja dalam suatu organisasi dapat memberikan dampak pada kinerja individu yang kemudian akan mempengaruhi sikap dan perilakunya dalam mempertahankan keanggotannya dalam organisasi. Penelitian ini bertujuan untuk mengetahui hubungan antara iklim organisasi dengan komitmen organisasi pada pegawai Lembaga Pemasyarakatan Kelas I Semarang. Populasi penelitian sebanyak 118 orang pegawai Lembaga Pemasyarakatan Kelas I Semarang. Uji coba diberikan kepada 35 orang pegawai dan penelitian dilakukan kepada 60 orang pegawai, yang ditentukan dengan menggunakan teknik random sampling. Alat ukur yang digunakan pada penelitian ini adalah Skala Komitmen Organisasi (34 aitem, α = .907) dan Skala Iklim Organisasi (46 aitem, α = .944). Dari hasil uji statistik non-parametrik Kendall’s Tau menunjukkan adanya hubungan antara iklim organisasi dengan komitmen organisasi (r = .590; p = .000). Hal ini menunjukkan terdapat hubungan positif dan signifikan antara iklim organisasi dengan komitmen organisasi pada pegawai petugas pemasyarakatan Lembaga Pemasyarakatan Kelas I Semarang. Iklim organisasi memberikan sumbangan efektif sebesar 70,8% terhadap komitmen organisasi.

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Zecchin de Fasano, Graciela C. « Intromisiones líricas en Odisea ». Synthesis 29, n^o 1 (1 avril 2022) : e119. http://dx.doi.org/10.24215/1851779xe119.

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Se suele explicar el origen de las composiciones líricas de la Literatura Griega Clásica utilizando como testimonio inicial pasajes de Ilíada, que refieren a un peán (I.472), a un himeneo (XVI.182) o a canciones danzadas (XVIII.560-570 y 590-605). El objetivo del presente artículo es analizar tres pasajes en los que es posible explorar dentro de Odisea, el juego de una performance de discursos líricos corales que fluyen bajo la coerción del formato épico. Se abordan el lamento de Penélope en el canto 4.722-734, la incidencia del ambiente del partenio en el canto 6.99-109 y la versión del treno de las Musas en los funerales por Aquiles en el canto 24.58-62.

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POGLIANO, CLAUDIO. « MARIO BIAGIOLI (ed.), The Science Studies Reader, (in consultation with Peter Galison, Donna J. Haraway, Everett Mendelsohn, Sharon Traweek), New York and London, Routledge, 1999, 590 pp. » Nuncius 14, n^o 2 (1 janvier 1999) : 675–77. http://dx.doi.org/10.1163/221058799x00133.

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Nagata, I., A. Kawana et N. Nakatsuji. « Perpendicular contact guidance of CNS neuroblasts on artificial microstructures ». Development 117, n^o 1 (1 janvier 1993) : 401–8. http://dx.doi.org/10.1242/dev.117.1.401.

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Rodent CNS neuroblasts show parallel and perpendicular contact guidance behaviors on aligned neurite bundles in microexplant cultures (Nakatsuji, N. and Nagata, I. (1989) Development, 106, 441–447; N. I. and N. N. (1991) ibid., 112, 581–590). To test the hypothesis that the physical surface structure of the neurite bundle causes the perpendicular contact guidance, we cultured dissociated neuroblasts on quartz plates on which grating-like microstructures were fabricated by lithographic techniques. Various types of CNS neuroblasts, but not PNS neurons, oriented their processes and migrated both perpendicular and parallel to the axis of the microstructure. Perpendicular orientation was frequently observed when the microstructured grooves had depths between 0.3 micron and 0.8 micron and a width of 1 micron, which roughly mimics a tightly aligned neurite bundle. Thus, CNS neuroblasts have the ability to extend their processes and migrate perpendicular to aligned surface microstructures.

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Kudchadker, R., W. Du, T. Bruno, T. Pugh et S. Frank. « SU-E-T-590 : Treatment Planning Dosimetry Comparison Between Model 9011 I-125 ThinSeed and Model 6711 I-125 Seeds for Prostate Implant Brachytherapy ». Medical Physics 38, n^o 6Part20 (juin 2011) : 3625. http://dx.doi.org/10.1118/1.3612552.

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Ghazalli, Nur Fatiha, Leny Yuliati, Salasiah Endud, Mustaffa Shamsuddin et Hendrik O. Lintang. « Vapochromic Copper (I) Pyrazolate Complex Materials for Phosphorescent Chemosensors of Ethanol ». Advanced Materials Research 970 (juin 2014) : 44–47. http://dx.doi.org/10.4028/www.scientific.net/amr.970.44.

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Here chemosensor materials of trinuclear copper (I) pyrazolate complexes have been successfully synthesized and isolated using two types of 3,5-dimethyl and 4-(3,5-dimethoxybenzyl)-3,5-dimethyl pyrazole ligands. Upon excitation at 280 nm, the resulting trinuclear 3,5-dimethyl copper (I) pyrazolate complex (complex A) and trinuclear 4-(3,5-dimethoxybenzyl) copper (I) pyrazolate complex (complex B) showed emission bands centered at 590 and 604 nm, respectively. These results were in good agreement with their greenish-white powders and it is characteristic of phosphorescent metal complexes from the weak Cu (I)-Cu (I) metallophilic interaction. Upon direct or stepwise exposure to ethanol vapor with series of concentrations (12.5, 25, 50, 100, 150 and 200μL in 22 mg of chemosensor), the emission of chemosensor complex A was not shifted even after 1 d. Interestingly, chemosensor complex B showed gradually changes in both emission band with shifting from 602 to 552 nm and color with changing from orange to green under Ultra-violet (UV) hand lamp (254 nm) at the dark room due to the attachment of benzyl ring to the pyrazole ligand. This positive response for chemosensor complex B was reversible; hence, this optical phosphorescent material can be used for developing vapochromic sensors of ethanol.

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Monique-Adelle Callahan D. « A Tradition of Rising [1963 et al.]/I, Too, Sing America/Tribute/Hymn #590 : Sabbath Riots/Hymn #643 : Split ». Transition, n^o 125 (2018) : 71. http://dx.doi.org/10.2979/transition.125.1.10.

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Holford-Strevens, Leofranc. « Berlin Latin Manuscripts Now in Cracow ». Classical Quarterly 42, n^o 2 (décembre 1992) : 577–78. http://dx.doi.org/10.1017/s000983880001630x.

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In L. D. Reynolds (ed.), Texts and Transmission: a Survey of the Latin Classics (Oxford, 1983), it is stated by J. G. F. Powell (p. 122) and by M. D. Reeve (p. 327 n. 4) that MS. Berlin, Deutsche Staatsbibliothek Lat. 4° 404 (s. ix), containing Cicero, De amicitia, and Publilius Syrus, Sententiae, is missing. Not so: it is currently held with numerous other Berlin MSS., including humanistic and musical autographs, at the Jagellonian Library in Cracow, where I saw it on 5 May 1992. Other classical MSS. from Berlin now held in Cracow are Lat. 4° 1 (Eutropius, Breviarium, and Victor Vitensis, Historia persecutions Africanae prouinciae, s. xi), 257 (Vergil, Bucolics 3.107–4.47, s. ix), 590 (Boethius, opuscula, s. xii), 939 (Boethius, Cons. Phil. with Remigius' commentary, s. x/xi; till 1935 Schloβ Maihingen, Fürstlich Öttingen-Wallensteinsche Bibliothek, I 2, lat. 4° 3), and 8° 102 (Statius, Achilleis, 1.375–513, 2.120–257, s. xiv).

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Srimudkul, Omsin, Zoe C. Venables, Nick J. Levell, Khaylen Mistry et Birgitta Van Bodegraven. « O13 42 590 fewer skin tumours diagnosed in England during the 2020 COVID pandemic : greatest reductions in melanoma in situ, stage I melanomas and basal cell carcinomas ». British Journal of Dermatology 191, Supplement_1 (28 juin 2024) : i8. http://dx.doi.org/10.1093/bjd/ljae090.013.

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Abstract During the early COVID-19 pandemic, there was a decline in most cancer diagnoses. The aim of this study was to ascertain the extent and impact of this on skin cancer subtypes in England. This national retrospective cohort study identified all skin tumour cases diagnosed in 2019 and 2020 in England from the National Disease Registration Service ‘Get Data Out’ project. Incidence rate ratios (IRRs) with 95% confidence intervals (CIs) and Poisson regression analysis were used to compare crude incidence rates (CIR) per 100 000 person-years (PY) in 2020 vs. 2019. In 2019, there were 233 717 skin tumours registered in England; this reduced to 191 127 (IRR 0.81, 95% CI 0.80–0.81, P < 0.001) in 2020. A year prior to the pandemic, there were 15 355 (CIR 27.3 PY) melanomas, 7135 (CIR 12.7 PY) melanomas in situ, 48 112 (CIR 85.5 PY) cutaneous squamous cell carcinomas (cSCCs), 159 178 (CIR 283 PY) basal cell carcinomas (BCCs) and 363 (CIR 0.65 PY) Merkel cell carcinomas (MCCs). When comparing incidence rates for 2020 vs. 2019, significant reductions (P < 0.001) were seen in all tumours except MCC: melanoma (IRR 0.81, 95% CI 0.79–0.83), melanoma in situ (IRR 0.65, 95% CI 0.63–0.68), cSCC (IRR 0.94, 95% CI 0.93–0.96), BCC (IRR 0.78, 95% CI 0.78–0.79) and MCC (IRR 0.93, 95% CI 0.80–1.08). For melanoma by stage, there were 8940 (CIR 22.6 PY) stage I, 2441 (CIR 6.18 PY) stage II, 1004 (CIR 2.54 PY) stage III, 385 (CIR 0.97 PY) stage IV and 2187 (CIR 5.53 PY) stage ‘unknown’ in 2019. The IRR for 2020 vs. 2019 showed significant reductions (P < 0.001) for stage I (IRR 0.76, 95% CI 0.73–0.78) and stage ‘unknown’ melanomas (IRR 0.67, 95% CI 0.62–0.71), while changes were not significant for all other stages. During the 2020 COVID pandemic, there was a 19% reduction in diagnosed skin tumours in England. There was a differential impact between tumour types and stages, with the greatest reduction seen in melanoma in situ (−35%), stage I melanoma (−24%) and BCC (−22%), compared with MCC (−7%), cSCC (−6%) and stage II+ melanoma (+2%). The improvement to staging data in 2020 (−33% ‘unknown’ stage melanomas) limits interpretation, but these account for < 15% of cases of melanoma. It is hypothesized that symptomatic and slow-growing tumours were not prioritized by patients and/or clinicians, potentially resulting in worse patient outcomes and increased burden on health services. This indicates a need for more time to study the impact of delayed diagnosis on survival, better public education on skin cancer recognition, and improved service provision during national emergencies.

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Tariq, Hassan, Muhammad Rashid, Asfa Javed, Muhammad Aaqib Riaz, Mohammed Sinky et Muhammad Yousuf Irfan Zia. « Implementation of Omni-D Tele-Presence Robot Using Kalman Filter and Tricon Ultrasonic Sensors ». Sensors 22, n^o 10 (23 mai 2022) : 3948. http://dx.doi.org/10.3390/s22103948.

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The tele-presence robot is designed to set forth an economic solution to facilitate day-to-day normal activities in almost every field. There are several solutions to design tele-presence robots, e.g., Skype and team viewer, but it is pretty inappropriate to use Skype and extra hardware. Therefore, in this article, we have presented a robust implementation of the tele-presence robot. Our proposed omnidirectional tele-presence robot consists of (i) Tricon ultrasonic sensors, (ii) Kalman filter implementation and control, and (iii) integration of our developed WebRTC-based application with the omnidirectional tele-presence robot for video transmission. We present a new algorithm to encounter the sensor noise with the least number of sensors for the estimation of Kalman filter. We have simulated the complete model of robot in Simulink and Matlab for the tough paths and critical hurdles. The robot successfully prevents the collision and reaches the destination. The mean errors for the estimation of position and velocity are 5.77% and 2.04%. To achieve efficient and reliable video transmission, the quality factors such as resolution, encoding, average delay and throughput are resolved using the WebRTC along with the integration of the communication protocols. To protect the data transmission, we have implemented the SSL protocol and installed it on the server. We tested three different cases of video resolutions (i.e., 320×280, 820×460 and 900×590) for the performance evaluation of the video transmission. For the highest resolution, our TPR takes 3.5 ms for the encoding, and the average delay is 2.70 ms with 900 × 590 pixels.

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Missio, Regis Luis, Luis Fernando Glasenapp de Menezes, Ivan Luiz Brondani, José Laerte Nörnberg, Paulo Santana Pacheco, Fernando Kuss, Magali Floriano da Silveira et João Restle. « Fatty acid profile of duodenal digesta and of meat of feedlot beef cattle fed diets containing different levels of concentrate ». Semina : Ciências Agrárias 40, n^o 6Supl3 (16 octobre 2019) : 3629. http://dx.doi.org/10.5433/1679-0359.2019v40n6supl3p3629.

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The objective of this study was to evaluate the fatty acid profile of duodenal digesta (experiment I) and of meat of beef cattle (experiment II) fed diets containing different levels of concentrate (220, 400, 590 and 790 g of concentrate/kg of dry matter of the diets). The experiment I was conducted with four Charolais-Nellore steers (460 ± 18.2 kg of BW), with a T-shaped duodenal cannula, using a double 4 × 4 Latin square as an experimental design. In experiment II, 16 crossbred Charolais-Nellore young bulls (192.44 ± 18.2 kg of BW) were randomly distributed in the experimental treatments (220, 400, 590 and 790 g of concentrate/kg of dry matter of the diets). The diets were isonitrogenous (120 g of crude protein/kg of dry matter). The intramuscular fat content was used as a covariant for the statistical analysis of the meat fatty acid profile. The duodenal content of fatty acid C17:0 decreased with increase of concentrate levels, while its content in the meat presented a quadratic variation with the increase of the concentrate levels of the diets, being the lowest values observed for the diet with 400 g of concentrate. The duodenal content of fatty acid C18:1 trans-11 decreased, whereas the content of this fatty acid in the meat increased with the increase of the dietary concentrate levels. The increase in the level of concentrate reduced the content of polyunsaturated fatty acids C18:3 n-3, C20:3 n-6, C20:4 n-6, and C20:5 n-3 EPA in both the duodenal digesta and meat. No difference was observed in the n-6/n-3 fatty acids ratio (mean of 13.96) of the meat between diets. The elevation of the level of concentrate in confinement diets reduces the nutraceutical quality of the meat of Charolais-Nellore young bulls slaughtered at 14-16 months of age due to the reduction of the polyunsaturated fatty acids content important for human health.

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Staehler, Michael D., Boris Schlenker, Alexander Karl, Annabel Spek et Alexander Muacevic. « Single-fraction radiosurgery for the treatment of renal cell carcinoma. » Journal of Clinical Oncology 34, n^o 2_suppl (10 janvier 2016) : 590. http://dx.doi.org/10.1200/jco.2016.34.2_suppl.590.

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590 Background: We report on patients with renal cell carcinoma (RCC) who were treated with single fraction high-dose local stereotactic radiosurgery (SRS) using the robotic Cyberknife system to avoid nephrectomy and consecutive hemodialysis. Methods: Fifty-two patients with histologically confirmed RCC and median age of 63.6 years (43.6-86.5) with the indication for renal surgery and highest risk for consecutive hemodialysis were entered into a prospective case control study of single fraction SRS with 25Gy. Tumor response, renal function, survival, and adverse events were estimated every three months with a follow-up of at least six months. Results: R.E.N.A.L. score was low in 1, moderate in 30 and high in 21 patients. 28 patients had singular renal units. Median follow-up was 26.9 months (1.8 - 52.6). Local tumor control nine months after SRS was 98% (95% CI: 89-99%). 43 lesions showed a measurable tumor size reduction including six complete remissions and 33 partial remissions. Renal function remained stable with a median serum creatinine at baseline of 1.10 mg/dl (0.4 -2.0) and 1.11 mg/dl (0.8-2.2) at follow-up. In one patient grade I erythrodermia, in three patients grade I fatigue and in two patients grade I nausea occurred. In all patients nephrectomy was avoided. Conclusions: Single-fraction SRS as an outpatient procedure is a treatment modality with short-term safety and efficacy to avoid treatment-related loss of renal function and hemodialysis in selected patients with RCC. Short term follow up of oncological and functional results so far is excellent. Further studies are needed to determine the limits of SRS in this setting and long term results.

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Almagro-Gorbea, Martín. « Una probable divinidad tartésica identificada : NIETHOS/NETOS ». Palaeohispanica. Revista sobre lenguas y culturas de la Hispania Antigua, n^o 2 (10 décembre 2019) : 37–70. http://dx.doi.org/10.36707/palaeohispanica.v0i2.347.

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Un interesante grafito NIH80I sobre un cuenco milesio hallado con cerámicas de la Grecia Oriental del 590–560 a.C. en un posible ambiente de santuario portuario en la ciudad tartésica de Onuba parece ser el pri- mer teónimo tartésico conocido. Niethos se puede relacionar con Neton, divinidad solar y guerrera de Acci (Macrobio, I,19,5); su raíz indoeuropea, *nith-, *neith-, que signi- fica “héroe, guerrero”, “brillar” y “santo”, se documenta en Celta y qui- zás también en el celtibérico neito y en el ibérico neitin. El teónimo Niethos-Neton confirmaría la presencia de Celtas en Tartessos a inicios del siglo VI a.C. y su carácter solar y guerrero puede considerarse propio de un smiting god orientalizante tartésico, con funciones de divinidad dinástica garante de los intercambios coloniales.

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Erbs, Emilie, Søren Rafael Rafaelsen, Jan Lindebjerg, Lars Henrik Jensen et Torben Frøstrup Hansen. « The impact of mismatch repair status to the preoperative staging of colon cancer : implications for clinical management ». Colorectal Cancer 9, n^o 2 (juillet 2020) : CRC20. http://dx.doi.org/10.2217/crc-2020-0001.

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Aims: We sought to investigate if mismatch repair (MMR) status influences the preoperative staging of local colon cancer. Methods: Data from 590 patients in the Danish Colorectal Cancer Group national clinical database who were operated on for stage I-III colon cancer in 2010-15 were included. MMR status was determined by immunohistochemistry. Results: 22.9% had deficient(d) MMR tumors. Correlation of the clinical and pathological T-category was significant for both groups. The correlation of pre- and postoperative N-category was inferior (p >0.05) in dMMR cancers compared to a significant (p <0.01) correlation in proficient MMR cancers. 64.8% of dMMR tumors assessed node-positive demonstrated no sign of metastatic involvement at the postoperative assessment. Conclusion: MMR status seems to impact the accuracy of preoperative lymph node staging.

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Mendoza Conde, Gabriel Omar, José Alberto Luna López, Zaira Jocelyn Hernández Simón, José Álvaro David Hernández de la Luz, Godofredo García Salgado, Erick Gastellou Hernández, Haydee Patricia Martínez Hernández et Javier Flores Méndez. « MIS-Like Structures with Silicon-Rich Oxide Films Obtained by HFCVD : Their Response as Photodetectors ». Sensors 22, n^o 10 (21 mai 2022) : 3904. http://dx.doi.org/10.3390/s22103904.

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MIS-type structures composed of silicon-rich oxide (SRO), thin films deposited by hot filament chemical vapor deposition (HFCVD), show interesting I-V and I-t properties under white light illumination and a response as photodetectors. From electrical measurements, it was found that at a reverse bias of −4 V, the illumination current increased by up to three orders of magnitude relative to the dark current, which was about 82 nA, while the photogenerated current reached a value of 25 μA. The reported MIS structure with SRO as the dielectric layer exhibited a hopping conduction mechanism, and an ohmic conduction mechanism was found with low voltage. I-t measurements confirmed the increased photogenerated current. Furthermore, the MIS structure, characterized by current-wavelength (I-λ) measurements, exhibited a maximum responsivity value at 254 mA/W, specific detectivity (D*) at 2.21 × 1011 cm Hz1/2 W−1, and a noise equivalent power (NEP) of 49 pW at a wavelength of 535 nm. The structure exhibited good switching behavior, with rise and fall times between 120 and 150 ms, respectively. These rise and decay times explain the generation and recombination of charge carriers and the trapping and release of traps, respectively. These results make MIS-type structures useful as photodetectors in the 420 to 590 nm range.

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Andrew Louth. « Byzantine Rome and the Greek Popes : Eastern Influences on Rome and the Papacy from Gregory the Great to Zacharias, A. D. 590-752 (review) ». Catholic Historical Review 94, n^o 4 (2008) : 779–80. http://dx.doi.org/10.1353/cat.0.0164.

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