Littérature scientifique sur le sujet « GE11 »

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Articles de revues sur le sujet "GE11"

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Du, Longhai, Yanlong Xu, Binxu Han, et al. "EGFR-targeting peptide conjugated polymer–lipid hybrid nanoparticles for delivery of salinomycin to osteosarcoma." Journal of Cancer Research and Therapeutics 19, no. 6 (2023): 1544–51. http://dx.doi.org/10.4103/jcrt.jcrt_2503_22.

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Context: Salinomycin (SAL) is a chemotherapeutic drug with anti-osteosarcoma efficacy, but its hydrophobic properties have hindered its application. Nanoparticles have been widely used as drug carriers to improve the solubility of hydrophobic drugs. The dodecapeptide GE11 has been shown to have great binding affinity to the epidermal growth factor receptor (EGFR), which is highly overexpressed in osteosarcoma. Materials and Methods: We designed novel SAL-loaded GE11-conjugated polymer–lipid hybrid nanoparticles (GE11-NPs-SAL) to target osteosarcoma. The characterization and antitumor activity
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Chiesa, Enrica, Silvia Pisani, Barbara Colzani, et al. "Intra-Articular Formulation of GE11-PLGA Conjugate-Based NPs for Dexamethasone Selective Targeting—In Vitro Evaluation." International Journal of Molecular Sciences 19, no. 8 (2018): 2304. http://dx.doi.org/10.3390/ijms19082304.

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Selectively targeted nanoscale drug delivery systems have recently emerged as promising intravenously therapeutic option for most chronic joint diseases. Here, a newly synthetized dodecapeptide (GE11)-polylactide-co-glycolide (PLGA)-based conjugate was used to prepare smart nanoparticles (NPs) intended for intra-articular administration and for selectively targeting Epidermal Growth Factor Receptor (EGFR). GE11-PLGA conjugate-based NPs are specifically uptaken by EGFR-overexpressed fibroblast; such as synoviocytes; which are the primarily cellular component involved in the development of destr
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Gaurav, Isha, Abhimanyu Thakur, Kui Zhang, et al. "Peptide-Conjugated Vascular Endothelial Extracellular Vesicles Encapsulating Vinorelbine for Lung Cancer Targeted Therapeutics." Nanomaterials 14, no. 20 (2024): 1669. http://dx.doi.org/10.3390/nano14201669.

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Lung cancer is one of the major cancer types and poses challenges in its treatment, including lack of specificity and harm to healthy cells. Nanoparticle-based drug delivery systems (NDDSs) show promise in overcoming these challenges. While conventional NDDSs have drawbacks, such as immune response and capture by the reticuloendothelial system (RES), extracellular vesicles (EVs) present a potential solution. EVs, which are naturally released from cells, can evade the RES without surface modification and with minimal toxicity to healthy cells. This makes them a promising candidate for developin
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Huang, Xueqin, Lingzhi Chen, Yuping Zhang, et al. "GE11 Peptide Conjugated Liposomes for EGFR-Targeted and Chemophotothermal Combined Anticancer Therapy." Bioinorganic Chemistry and Applications 2021 (March 31, 2021): 1–15. http://dx.doi.org/10.1155/2021/5534870.

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How to actively target tumor sites manipulating the controllable release of the encapsulated anticancer drugs and photosensitizers for synergistic anticancer therapy remains a big challenge. In this study, a cancer cell-targeted, near-infrared (NIR) light-triggered and anticancer drug loaded liposome system (LPs) was developed for synergistic cancer therapy. Photosensitizer indocyanine green (ICG) and chemotherapy drug Curcumin (CUR) were coencapsulated into the liposomes, followed by the surface conjugation of GE11 peptide for epidermal growth factor receptor (EGFR) targeting on the cancer ce
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Li, Kaichun, Liying Pang, Xiaorong Pan, et al. "GE11 Modified PLGA/TPGS Nanoparticles Targeting Delivery of Salinomycin to Breast Cancer Cells." Technology in Cancer Research & Treatment 20 (January 1, 2021): 153303382110049. http://dx.doi.org/10.1177/15330338211004954.

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Salinomycin (Sal) is a potent inhibitor with effective anti-breast cancer properties in clinical therapy. The occurrence of various side effect of Sal greatly limits its application. The epidermal growth factor receptor (EGFR) family is a family of receptors highly expressed in most breast cancer cells. GE11 is a dodecapeptide which shows excellent EGFR affinity. A series of nanoparticles derivatives with GE11 peptide conjugated PLGA/TPGS were synthesized. Nanoprecipitation method was used to prepare the Sal loaded nanoparticles at the optimized concentration. The characterization, targeting e
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Gimond, Clotilde, Arjan van der Flier, Sanne van Delft та ін. "Induction of Cell Scattering by Expression of β1 Integrins in β1-Deficient Epithelial Cells Requires Activation of Members of the Rho Family of Gtpases and Downregulation of Cadherin and Catenin Function". Journal of Cell Biology 147, № 6 (1999): 1325–40. http://dx.doi.org/10.1083/jcb.147.6.1325.

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Adhesion receptors, which connect cells to each other and to the surrounding extracellular matrix (ECM), play a crucial role in the control of tissue structure and of morphogenesis. In this work, we have studied how intercellular adhesion molecules and β1 integrins influence each other using two different β1-null cell lines, epithelial GE11 and fibroblast-like GD25 cells. Expression of β1A or the cytoplasmic splice variant β1D, induced the disruption of intercellular adherens junctions and cell scattering in both GE11 and GD25 cells. In GE11 cells, the morphological change correlated with the
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Gé, Lorraine Gaenaelle, Mathias Bogetoft Danielsen, Aaraby Yoheswaran Nielsen, et al. "Radiocobalt-Labeling of a Polypyridylamine Chelate Conjugated to GE11 for EGFR-Targeted Theranostics." Molecules 30, no. 2 (2025): 212. https://doi.org/10.3390/molecules30020212.

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The overexpression of the epidermal growth factor receptor (EGFR) in certain types of prostate cancers and glioblastoma makes it a promising target for targeted radioligand therapy. In this context, pairing an EGFR-targeting peptide with the emerging theranostic pair comprising the Auger electron emitter cobalt-58m (58mCo) and the Positron Emission Tomography-isotope cobalt-55 (55Co) would be of great interest for creating novel radiopharmaceuticals for prostate cancer and glioblastoma theranostics. In this study, GE11 (YHWYGYTPQNVI) was investigated for its EGFR-targeting potential when conju
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Yang, Chengcheng, Xuan Mi, Huilan Su, et al. "GE11-PDA-Pt@USPIOs nano-formulation for relief of tumor hypoxia and MRI/PAI-guided tumor radio-chemotherapy." Biomaterials Science 7, no. 5 (2019): 2076–90. http://dx.doi.org/10.1039/c8bm01492b.

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Lee, Duhwan, Yeong Mi Lee, Jihoon Kim, Myung Kyu Lee, and Won Jong Kim. "Enhanced tumor-targeted gene delivery by bioreducible polyethylenimine tethering EGFR divalent ligands." Biomaterials Science 3, no. 7 (2015): 1096–104. http://dx.doi.org/10.1039/c5bm00004a.

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Gaugaz, Fabienne, Andrea Chicca, Mariano Redondo-Horcajo, Isabel Barasoain, J. Díaz, and Karl-Heinz Altmann. "Synthesis, Microtubule-Binding Affinity, and Antiproliferative Activity of New Epothilone Analogs and of an EGFR-Targeted Epothilone-Peptide Conjugate." International Journal of Molecular Sciences 20, no. 5 (2019): 1113. http://dx.doi.org/10.3390/ijms20051113.

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A new simplified, epoxide-free epothilone analog was prepared incorporating an N-(2-hydroxyethyl)-benzimidazole side chain, which binds to microtubules with high affinity and inhibits cancer cell growth in vitro with nM potency. Building on this scaffold, a disulfide-linked conjugate with the purported EGFR-binding (EGFR, epidermal growth factor receptor) peptide GE11 was then prepared. The conjugate retained significant microtubule-binding affinity, in spite of the size of the peptide attached to the benzimidazole side chain. The antiproliferative activity of the conjugate was significantly l
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Thèses sur le sujet "GE11"

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COLZANI, BARBARA. "Sviluppo di sistemi terapeutici nanoparticellari a base di nuovi derivati dell’acido polilattico finalizzati al trattamento di patologie ossee." Doctoral thesis, Università degli Studi di Pavia, 2015. http://hdl.handle.net/10281/147786.

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Il polilattide (PLA) e il suo co-polimero con l’acido glicolico (PLGA) appartengono alla famiglia dei poli-esteri alifatici, polimeri di sintesi frequentemente utilizzati in ambito farmaceutico per la loro biocompatibilità e scarsa citotossicità, approvati FDA per la somministrazione parenterale. Esistono però alcune limitazioni nell’uso del PLA e derivati nella realizzazione di sistemi di rilascio controllato dei farmaci, come nanoparticelle (NP). In particolare, il PLA è caratterizzato da un’elevata idrofobicità e da un elevato grado di cristallinità che rendono il profilo di degradazione d
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Cano, Lazarte Mercedes Elena, Paredes Maribel Perez, Garcia Jose Antonio Rojas, and Sifuentes Carlos Luis Torres. "Fundamentos de ingeniería de gestión empresarial - GE01 201801." Universidad Peruana de Ciencias Aplicadas (UPC), 2018. http://hdl.handle.net/10757/624413.

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Descripción: La situación empresarial del mundo en la actualidad está cambiando rápidamente, se está dando paso a la incorporación de nuevos competidores, el aumento de alianzas, fusiones y adquisiciones, la mayor demanda de calidad y servicio, los grandes avances tecnológicos y la creación de una estructura global de los mercados. Dada esa coyuntura, el mercado laboral necesita cada vez más profesionales capaces de gestionar empresas, creando nuevas o conduciendo eficientemente las existentes hacia el éxito. En este sentido, el curso proporciona al alumno los conocimientos y habilidades
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Majure, Lucas Charles. "The ecology and morphological variation of Opuntia (Cactaceae) species in the mid-south, United States /." View online, 2007. http://www.msstate.edu/courses/ge14/students/Majure_Thesis.pdf.

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Hawkins, Timothy James. "A study of M0R1/GEM1 and kinl-like kinesins in Arabidopsis." Thesis, Durham University, 2004. http://etheses.dur.ac.uk/3039/.

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Microtubules perform essential functions in eukaryotic cells and, with other cytoskeletal elements, are involved in diverse cellular processes. Plant cells construct four microtubule arrays; There are two cortical arrays, the interphase cortical array, and the preprophase band, the mitotic spindle and the cytokinetic phragmoplast. The control and rearrangement of these arrays through the cell cycle is coordinated by Microtubule Associated Proteins or MAPs. These proteins have diverse functions including anchoring & crosslinking microtubules or otherwise regulating microtubule formation and
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Dunn, Francis X. "Thrust modulated multivariable control of the GE21 engine using the LQG/LTR method." Thesis, Massachusetts Institute of Technology, 1986. http://hdl.handle.net/1721.1/15000.

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Thesis (M.S.)--Massachusetts Institute of Technology, Dept. of Electrical Engineering and Computer Science, 1986.<br>MICROFICHE COPY AVAILABLE IN ARCHIVES AND ENGINEERING<br>Bibliography: leaves 173-175.<br>by Francis X. Dunn.<br>M.S.
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Chakrama, Fatima Zahra. "La protéine Gec1/Gabarapl1 : rôle au cours de l'autophagie et expression dans les cellules cancéreuses." Thesis, Besançon, 2011. http://www.theses.fr/2011BESA3007/document.

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Le gène Gec1/Gabarapl1 a été identifié au sein de notre laboratoire comme un gène régulé par les estrogènes. Il appartient à la famille Gabarap incluant les gènes Gabarap, gabarap/2 et Gabarapl3 qui codent des protéines présentant de fortes homologies de séquences. L'étude fonctionnelle de Gabarapl 1 a montré que cette protéine est impliquée dans le transport des récepteurs et particulièrement les récepteurs Gabaₐ et des κ-opioïdes via son interaction avec la tubuline et la protéine NSF. Cependant, il a été décrit que certaines protéines de la famille Atg8 sont impliquées dans l' autophagie, u
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Tolle, Fabrice. "Le gène gec1 : expression dans le système nerveux central, estrogéno-dépendance et rôle dans l'oncogenèse." Besançon, 2008. http://www.theses.fr/2008BESA3001.

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Notre équipe a montré une expression préférentielle de gec1 dans le Système Nerveux Central (SNC) et une faible expression dans diverses lignées cancéreuses. Nos objectifs ont été d'étudier: l'expression de gec1 dans le cerveau de rat ; le rôle de gec1 dans !'oncogenèse ; l'effet des estrogènes, in vivo et in vitro, sur l'expression de gec1. Tout d'abord, nous avons montré que gec1 est fortement exprimé dans le SNC de rat, et plus particulièrement dans les neurones impliqués dans les fonctions somesthèsiques, motrices et neuroendocrines. Au cours de !'oncogenèse, dans les méningiomes, une dimi
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Wang, Fei. "The intermediate phase and stress in Ge1/4 Se3/4-yIy glasses." Cincinnati, Ohio : University of Cincinnati, 2002. http://rave.ohiolink.edu/etdc/view?acc%5Fnum=ucin1037301587.

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Khelidj, Hamza. "Elaboration de films minces semi-conducteurs Ge1-xSnx et leurs contacts ohmiques." Electronic Thesis or Diss., Aix-Marseille, 2021. http://www.theses.fr/2021AIXM0406.

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L’objectif de cette thèse est d’étudier la fabrication de films minces semi-conducteurs Ge1–xSnx par pulvérisation cathodique magnétron et leurs contacts ohmiques par diffusion réactive. La cristallisation et la croissance cristalline de Ge1–xSnx ont été étudiées. La cristallisation d'une couche amorphe de Ge1–xSnx déposée à température ambiante conduit à la croissance de films polycristallins. De plus, la compétition entre la séparation de phases Ge/Sn et la croissance Ge1–xSnx empêche la formation de couches de Ge1–xSnx riches en Sn à gros grains sans formation d’îlots de β-Sn en surface. Ce
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Lee, Shun-Hsiao [Verfasser], and Elena [Akademischer Betreuer] Conti. "Structural and biochemical characterization of human GEN1 holliday junction resolvase / Shun-Hsiao Lee ; Betreuer: Elena Conti." München : Universitätsbibliothek der Ludwig-Maximilians-Universität, 2017. http://d-nb.info/117361625X/34.

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Livres sur le sujet "GE11"

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Muthaly, Krishnamoorthy. May 9 people power saves Malaysia: Mahathir leads the way : GE14 votes out corruption. Krishnamoorthy Muthaly, 2018.

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Rathus, Spencer A. Custom Social Psychology GE117. Wadsworth, 2014.

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ACP COMMUNICATING RESULTS GE119. Wadsworth Publishing, 2014.

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Robson, Walter. Ear2ear And the Gem1's. Donard Publishing, 2005.

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iclicker and Colin G. Calloway. First Peoples 4e & iClicker Gen1. Bedford/St. Martin's, 2012.

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Standards of Gerontological Nursing Ge12. Amer Nurses Assn, 1987.

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Jan, Wan Saiful Wan. Ge14: Will Urban Malays Support Pakatan Harapan? ISEAS - Yusof Ishak Institute, 2018.

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Jan, Saiful Wan. GE14: Will Urban Malays Support Pakatan Harapan? ISEAS - Yusof Ishak Institute, 2018.

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Bi, J. F., and K. L. Teo. Nanoscale Ge1−xMnxTe ferromagnetic semiconductors. Edited by A. V. Narlikar and Y. Y. Fu. Oxford University Press, 2017. http://dx.doi.org/10.1093/oxfordhb/9780199533053.013.17.

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This article discusses the structure characterizations, magnetic and transport behaviors of the nanoscale ferromagnetic semiconductors Ge1-xMnxTe grown by molecular beam epitaxy with various manganese compositions x ranging from 0.14 to 0.98. After providing an overview of the growth procedure and characterization, the article analyzes the structures of the Ge1-xMnxTe system using X-ray diffraction and high-resolution transmission electron microscopy. It then considers the optical, magnetic and transport properties of the semiconductors and shows that the crystal quality is degraded and the pr
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Long, Nate. EQCO510 Automotive Dual Channel USB 3. 1 Gen1 Reclocking Redriver Datasheet. Microchip Technology Incorporated, 2020.

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Chapitres de livres sur le sujet "GE11"

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Allan, Keith. "General semantics." In Handbook of Pragmatics. John Benjamins Publishing Company, 2022. http://dx.doi.org/10.1075/hop.m2.gen1.

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Streeck, Jürgen. "Gesture research." In Handbook of Pragmatics. John Benjamins Publishing Company, 2022. http://dx.doi.org/10.1075/hop.m2.ges1.

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Streeck, Jürgen. "Gesture research." In Handbook of Pragmatics. John Benjamins Publishing Company, 2020. http://dx.doi.org/10.1075/hop.22.ges1.

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Dobrina, Claudia. "Getting to the core of a terminological project." In Handbook of Terminology. John Benjamins Publishing Company, 2015. http://dx.doi.org/10.1075/hot.1.get1.

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von Flotow, Luise. "Gender in translation." In Handbook of Translation Studies. John Benjamins Publishing Company, 2010. http://dx.doi.org/10.1075/hts.1.gen1.

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Weber, Jörg. "Hydrogen in Ge1)." In Photonics and Electronics with Germanium. Wiley-VCH Verlag GmbH & Co. KGaA, 2015. http://dx.doi.org/10.1002/9783527650200.ch2.

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Dietl, T. "Ge1-xMnxTe: absorption." In New Data and Updates for IV-IV, III-V, II-VI and I-VII Compounds, their Mixed Crystals and Diluted Magnetic Semiconductors. Springer Berlin Heidelberg, 2011. http://dx.doi.org/10.1007/978-3-642-14148-5_259.

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Dietl, T. "Ge1-xMnxTe: resistivity." In New Data and Updates for IV-IV, III-V, II-VI and I-VII Compounds, their Mixed Crystals and Diluted Magnetic Semiconductors. Springer Berlin Heidelberg, 2011. http://dx.doi.org/10.1007/978-3-642-14148-5_260.

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Dietl, T. "Ge1-xMnxTe: magnetoresistance." In New Data and Updates for IV-IV, III-V, II-VI and I-VII Compounds, their Mixed Crystals and Diluted Magnetic Semiconductors. Springer Berlin Heidelberg, 2011. http://dx.doi.org/10.1007/978-3-642-14148-5_261.

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Dietl, T. "Ge1-xMnxTe: magnetization." In New Data and Updates for IV-IV, III-V, II-VI and I-VII Compounds, their Mixed Crystals and Diluted Magnetic Semiconductors. Springer Berlin Heidelberg, 2011. http://dx.doi.org/10.1007/978-3-642-14148-5_264.

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Actes de conférences sur le sujet "GE11"

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Pate, David S., Chineme Jeanfrances Onukwughara, Griffin C. Spence, Indika U. Arachchige, and Ümit Özgür. "Tunable Optical Properties and Recombination Dynamics of Ge1-x-ySiySnx Nanoalloys." In CLEO: Science and Innovations. Optica Publishing Group, 2024. http://dx.doi.org/10.1364/cleo_si.2024.sf2r.2.

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We report on quantum confined Ge1-x-ySiySnx nanocrystals demonstrating both size- and composition-tunable direct visible/NIR emission (1.77 – 2.47 eV) and recombination dynamics. Temperature-dependent time-resolved photoluminescence suggests significant enhancement of oscillator strengths with Si incorporation.
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Calzaferri, Simone. "Operation of CMS GE1/1 GEM detectors in Run-3." In 42nd International Conference on High Energy Physics. Sissa Medialab, 2024. https://doi.org/10.22323/1.476.0896.

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Idrees, Mariam, Eda Bilgiç, Günnur Pulat, and Nermin Topaloğlu Avşar. "Development of EGFR Targeting Peptide/Chlorin e6 Conjugates for Targeted Antitumor Activity on Breast Cancer." In 8th International Students Science Congress. ULUSLARARASI ÖĞRENCİ DERNEKLERİ FEDERASYONU (UDEF), 2024. https://doi.org/10.52460/issc.2024.059.

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Breast cancer is considered the primary cause of cancer-related deaths in women. Conventionally, different treatment strategies such as hormone therapy, radiation therapy, surgical operations and chemotherapy are utilized in the treatment of breast cancer. Although, chemotherapy aims to kill cancerous cells by interfering with DNA synthesis and cell divisions leads to damage to healthy tissues as well as tumor tissues. Considering the side effects of the conventional treatments, developing novel alternative methods is crucial for breast cancer treatment. Photodynamic therapy (PDT) has emerged
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Sakunasinha, Panarit, Suksan Suwanarat, and Surasak Chiangga. "Mid-infrared supercontinuum in a Ge11:5As24Se64:5chalcogenide waveguide." In International Conference on Photonics Solutions 2015, edited by Surasak Chiangga and Sarun Sumriddetchkajorn. SPIE, 2015. http://dx.doi.org/10.1117/12.2196150.

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Aziz, Haris, and Simon Rey. "Almost Group Envy-free Allocation of Indivisible Goods and Chores." In Twenty-Ninth International Joint Conference on Artificial Intelligence and Seventeenth Pacific Rim International Conference on Artificial Intelligence {IJCAI-PRICAI-20}. International Joint Conferences on Artificial Intelligence Organization, 2020. http://dx.doi.org/10.24963/ijcai.2020/6.

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We consider a multi-agent resource allocation setting in which an agent's utility may decrease or increase when an item is allocated. We take the group envy-freeness concept that is well-established in the literature and present stronger and relaxed versions that are especially suitable for the allocation of indivisible items. Of particular interest is a concept called group envy-freeness up to one item (GEF1). We then present a clear taxonomy of the fairness concepts. We study which fairness concepts guarantee the existence of a fair allocation under which preference domain. For two natural c
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Wang, Suyuan, Jun Zheng, Chunlai Xue, et al. "P+-Ge1−xSnx / p−-Ge1−x−ySixSny / n-Ge1−x−ySixSny NTFET analysis and the realization of n-Ge1−x−ySixSny ohmic contact." In 2016 16th International Workshop on Junction Technology (IWJT). IEEE, 2016. http://dx.doi.org/10.1109/iwjt.2016.7486667.

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De Landtsheere, Jannick. "TREMEC gen1 EDU – Double The Power!" In WCX SAE World Congress Experience. SAE International, 2023. http://dx.doi.org/10.4271/2023-01-0481.

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&lt;div class="section abstract"&gt;&lt;div class="htmlview paragraph"&gt;With the transition of vehicles to electric drivetrains comes also the need to find solutions for fun-to-drive high performance vehicle variants. These will require dedicated performance-oriented electric drive units. TREMEC is developing a first generation of such EDU. Key attributes for this 600 kW EDU are: two motors in the space of an OEM single motor unit, excellent efficiency in WLTP and performance drive cycles, thermal robustness. Extensive analysis has been performed to find the right technological ingredients t
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Broderick, Christopher A., Edmond J. O'Halloran, and Eoin P. O'Reilly. "Comparative analysis of electronic structure evolution in Ge1-xSnx and Ge1−xPbx alloys." In 2019 International Conference on Numerical Simulation of Optoelectronic Devices (NUSOD). IEEE, 2019. http://dx.doi.org/10.1109/nusod.2019.8806886.

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Asti, Antonio, Luca Mangani, and Antonio Andreini. "Application of a 1-D Predicting Tool to the Analysis of Pressure Oscillations in an Industrial Gas Turbine Combustor: GE10 Machine." In ASME Turbo Expo 2007: Power for Land, Sea, and Air. ASMEDC, 2007. http://dx.doi.org/10.1115/gt2007-27893.

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The development of current industrial gas turbines is strictly constrained by legislative requirements for low polluting emissions. Lean Premixed combustion technology has become through the years the necessary standard to meet such requirements. Premixed technology introduces a new range of problems: combustion instabilities in many operating conditions. Specifically, lean premixed flames pose the threat of pressure oscillations. This phenomenon is the effect of the strong interaction between combustion heat-release and fluid dynamics aspects. The prediction of acoustic oscillations and combu
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Zagarzusem, Khurelbaatar, Yeon-Ho Kil, Sim-Hoon Yuk, et al. "Ge1−xSnx/Ge heterostructure infrared photodetector." In 2015 IEEE Sensors. IEEE, 2015. http://dx.doi.org/10.1109/icsens.2015.7370598.

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Rapports d'organisations sur le sujet "GE11"

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Kim, Seung Jun. DNB performance with modified FY19-GEN1 tests. Office of Scientific and Technical Information (OSTI), 2019. http://dx.doi.org/10.2172/1545727.

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