Littérature scientifique sur le sujet « G-Computation »
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Articles de revues sur le sujet "G-Computation"
Breger, Tiffany L., Jessie K. Edwards, Stephen R. Cole, Daniel Westreich, Brian W. Pence et Adaora A. Adimora. « Two-stage g-computation ». Epidemiology 31, no 5 (septembre 2020) : 695–703. http://dx.doi.org/10.1097/ede.0000000000001233.
Texte intégralWang, Changping, Chaokun Wang, Gaoyang Guo, Xiaojun Ye et Philip S. Yu. « Efficient Computation of G-Skyline Groups ». IEEE Transactions on Knowledge and Data Engineering 30, no 4 (1 avril 2018) : 674–88. http://dx.doi.org/10.1109/tkde.2017.2777994.
Texte intégralLosev, Ivan V. « Computation of Weyl groups of $G$-varieties ». Representation Theory of the American Mathematical Society 14, no 02 (5 janvier 2010) : 9–69. http://dx.doi.org/10.1090/s1088-4165-10-00365-1.
Texte intégralHerman, Allen. « Using G-algebras for Schur index computation ». Journal of Algebra 260, no 2 (février 2003) : 463–75. http://dx.doi.org/10.1016/s0021-8693(02)00577-x.
Texte intégralLosev, I. V. « Computation of weight lattices of G-varieties ». Journal of Mathematical Sciences 161, no 1 (28 juillet 2009) : 70–96. http://dx.doi.org/10.1007/s10958-009-9537-5.
Texte intégralVansteelandt, S., et N. Keiding. « Invited Commentary : G-Computation-Lost in Translation ? » American Journal of Epidemiology 173, no 7 (16 mars 2011) : 739–42. http://dx.doi.org/10.1093/aje/kwq474.
Texte intégralWang, Aolin, et Onyebuchi A. Arah. « G-computation demonstration in causal mediation analysis ». European Journal of Epidemiology 30, no 10 (octobre 2015) : 1119–27. http://dx.doi.org/10.1007/s10654-015-0100-z.
Texte intégralHall, Michael J., Neil E. Olson et Roger D. Chamberlain. « Utilizing Virtualized Hardware Logic Computations to Benefit Multi-User Performance ». Electronics 10, no 6 (12 mars 2021) : 665. http://dx.doi.org/10.3390/electronics10060665.
Texte intégralChu, Yunn-Kuang, et Jau-Chuan Ke. « Mean response time for a G/G/1 queueing system : Simulated computation ». Applied Mathematics and Computation 186, no 1 (mars 2007) : 772–79. http://dx.doi.org/10.1016/j.amc.2006.08.048.
Texte intégralChatton, A., F. Le Borgne, M. Léger, R. Lenain et Y. Foucher. « G-computation et intelligence artificielle en inférence causale ». Revue d'Épidémiologie et de Santé Publique 69 (juin 2021) : S10—S11. http://dx.doi.org/10.1016/j.respe.2021.04.013.
Texte intégralThèses sur le sujet "G-Computation"
Sirota, Leite Fernanda. « Role of the amino acid sequences in domain swapping of the B1 domain of protein G by computation analysis ». Doctoral thesis, Universite Libre de Bruxelles, 2007. http://hdl.handle.net/2013/ULB-DIPOT:oai:dipot.ulb.ac.be:2013/210657.
Texte intégralThe stability of the wt and quadruple mutant GB1 monomers was assessed using the software DESIGNER, a fully automatic procedure that selects amino acid sequences likely to stabilize a given backbone structure (Wernisch et al. 2000). Results suggest that 3 of the mutations (L5V, F30V, A34F) have a destabilizing effect. The first mutation (L5V) forms destabilizing interactions with surrounding residues, while the second (F30V) is engaged in unfavorable interactions with the protein backbone, consequently causing local strain. Although the A34F substitution itself is found to contribute favorably to the stability of the monomer, this is achieved only at the expense of forcing the wild type W43 into a highly strained conformation concomitant with the formation of unfavorable interactions with both W43 and V54.
Finally, we also provide evidence that A34F mutation stabilizes the swapped dimer structure. Although we were unable to perform detailed protein design calculations on the dimer, due to the lower accuracy of the model, inspection of its 3D structure reveals that the 34F side chains pack against one another in the core of the swapped structure, thereby forming extensive non-native interactions that have no counterparts in the individual monomers. Their replacement by the much smaller Ala residue is suggested to be significantly destabilizing by creating a large internal cavity, a phenomenon, well known to be destabilizing in other proteins. Our analysis hence proposes that the A34F mutation plays a dual role, that of destabilizing the GB1 monomer structure while stabilizing the swapped dimer conformation.
In addition to the above study, molecular dynamics simulations of the wild type and modeled quadruple mutant GB1 structures were carried out at room and elevated temperatures (450 K) in order to sample the conformational landscape of the protein near its native monomeric state, and to characterize the deformations that occur during early unfolding. This part of the study was aimed at investigating the influence of the amino acid sequence on the conformational properties of the GB1 monomer and the possible link between these properties and the swapping process. Analysis of the room temperature simulations indicates that the mutant GB1 monomer fluctuates more than its wild type counter part. In addition, we find that the C-terminal beta-hairpin is pushed away from the remainder of the structure, in agreement with the fact that this hairpin is the structural element that is exchanged upon domain swapping. The simulations at 450 K reveal that the mutant protein unfolds more readily than the wt, in agreement with its decreased stability. Also, among the regions that unfold early is the alpha-helix C-terminus, where 2 out of the 4 mutations reside. NMR experiments by our collaborators have shown this region to display increased flexibility in the monomeric state of the quadruple mutant.
Our atomic scale investigation has thus provided insights into how sequence modifications can foster domain swapping of GB1. Our findings indicate that the role of the amino acid substitutions is to decrease the stability of individual monomers while at the same time increase the stability of the swapped dimer, through the formation of non-native interactions. Both roles cooperate to foster swapping.
Doctorat en sciences, Spécialisation biologie moléculaire
info:eu-repo/semantics/nonPublished
Breuer, Thomas [Verfasser], Regina [Akademischer Betreuer] Dittmann et Tobias G. [Akademischer Betreuer] Noll. « Development of ReRAM-based devices for logic- and computation-in-memory applications / Thomas Breuer ; Regina Dittmann, Tobias G. Noll ». Aachen : Universitätsbibliothek der RWTH Aachen, 2017. http://d-nb.info/1162499680/34.
Texte intégralHiggs, C. « A computational study of the G-protein-G-protein coupled receptor interaction ». Thesis, University of Essex, 2001. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.324216.
Texte intégralTaddese, Bruck. « Computational modelling of G protein-coupled receptors ». Thesis, University of Essex, 2012. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.589439.
Texte intégralHenne, Randal Marlow. « Computational studies of G-protein coupled receptors / ». Thesis, Connect to this title online ; UW restricted, 1999. http://hdl.handle.net/1773/8048.
Texte intégralDuong, Chi-Hong. « Approches statistiques en pharmacoépidémiologie pour la prise en compte des facteurs de confusion indirectement mesurés dans les bases de données médico-administratives : Application aux médicaments pris au cours de la grossesse ». Electronic Thesis or Diss., université Paris-Saclay, 2024. http://www.theses.fr/2024UPASR028.
Texte intégralHealthcare administrative databases are increasingly used in pharmacoepidemiology. However, the existence of unmeasured and uncontrolled confounders can bias analyses. In this work, we explore the value of leveraging the richness of data through large-scale selection of a large number of measured covariates correlated with unmeasured confounders to indirectly adjust for them. This concept is the cornerstone of the High-dimensional propensity score (hdPS), and we apply the same approach to G-computation (GC) and Targeted Maximum Likelihood Estimation (TMLE). Although these methods have been evaluated in some simulation studies, their performance on large real-world databases remains underexplored. This thesis aims to assess their contributions to mitigating the effect of directly or indirectly measured confounders in the French administrative health care database (SNDS) for pharmacoepidemiological studies in pregnant women. In Chapter 2, we used a set of reference drugs related to prematurity to compare the performance of the three methods. All reduced confounding bias, with GC showing the best performance. In Chapter 3, we conducted an hdPS analysis in a more complex modeling setting to investigate the controversial association between non-steroidal anti-inflammatory drugs (NSAIDs) and miscarriage. We implemented a Cox model with time-dependent variables and the “lag-time” approach to address other biases (immortal time bias and protopathic bias). We compared analyses adjusted for factors chosen according to the current literature with those chosen by the hdPS algorithm. In both types of analysis, NSAIDs were associated with an increased risk of miscarriage, and the observed differences in estimated risks could partly be explained by the difference between the causal estimands targeted by the approaches. Our work confirms the contribution of statistical methods to reducing confounding bias. It also highlights major challenges encountered during their practical application, related to the complexity of modeling and study design, as well as their computational cost
Simpson, Lisa Marie. « Computational studies of G protein-coupled receptor activation ». Thesis, University of Essex, 2010. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.520117.
Texte intégralHeo, Jiyoung Beauchamp Jesse L. « Computational studies of orphan G protein-coupled receptors / ». Diss., Pasadena, Calif. : California Institute of Technology, 2007. http://resolver.caltech.edu/CaltechETD:etd-11102006-144154.
Texte intégralDilner, David. « Profitability = f(G) : Computational Thermodynamics, Materials Design and Process Optimization ». Doctoral thesis, KTH, Materialvetenskap, 2016. http://urn.kb.se/resolve?urn=urn:nbn:se:kth:diva-191243.
Texte intégralQC 20160829
COMPASS
Baragatti, Meïli. « Sélection bayésienne de variables et méthodes de type Parallel Tempering avec et sans vraisemblance ». Thesis, Aix-Marseille 2, 2011. http://www.theses.fr/2011AIX22100/document.
Texte intégralThis thesis is divided into two main parts. In the first part, we propose a Bayesian variable selection method for probit mixed models. The objective is to select few relevant variables among tens of thousands while taking into account the design of a study, and in particular the fact that several datasets are merged together. The probit mixed model used is considered as part of a larger hierarchical Bayesian model, and the dataset is introduced as a random effect. The proposed method extends a work of Lee et al. (2003). The first step is to specify the model and prior distributions. In particular, we use the g-prior of Zellner (1986) for the fixed regression coefficients. In a second step, we use a Metropolis-within-Gibbs algorithm combined with the grouping (or blocking) technique of Liu (1994). This choice has both theoritical and practical advantages. The method developed is applied to merged microarray datasets of patients with breast cancer. However, this method has a limit: the covariance matrix involved in the g-prior should not be singular. But there are two standard cases in which it is singular: if the number of observations is lower than the number of variables, or if some variables are linear combinations of others. In such situations we propose to modify the g-prior by introducing a ridge parameter, and a simple way to choose the associated hyper-parameters. The prior obtained is a compromise between the conditional independent case of the coefficient regressors and the automatic scaling advantage offered by the g-prior, and can be linked to the work of Gupta and Ibrahim (2007).In the second part, we develop two new population-based MCMC methods. In cases of complex models with several parameters, but whose likelihood can be computed, the Equi-Energy Sampler (EES) of Kou et al. (2006) seems to be more efficient than the Parallel Tempering (PT) algorithm introduced by Geyer (1991). However it is difficult to use in combination with a Gibbs sampler, and it necessitates increased storage. We propose an algorithm combining the PT with the principle of exchange moves between chains with same levels of energy, in the spirit of the EES. This adaptation which we are calling Parallel Tempering with Equi-Energy Move (PTEEM) keeps the original idea of the EES method while ensuring good theoretical properties and a practical use in combination with a Gibbs sampler.Then, in some complex models whose likelihood is analytically or computationally intractable, the inference can be difficult. Several likelihood-free methods (or Approximate Bayesian Computational Methods) have been developed. We propose a new algorithm, the Likelihood Free-Parallel Tempering, based on the MCMC theory and on a population of chains, by using an analogy with the Parallel Tempering algorithm
Livres sur le sujet "G-Computation"
Altinakar, M. S. Computational modeling for the development of sustainable water-resources systems in Poland : US-Poland Technology Transfer Program US-AID award number : EEE-G-00-02-00015-00. Warszawa : Institute of Geophysics, Polish Academy of Science, 2005.
Trouver le texte intégralVychislitelʹnai︠a︡ filogenetika i genosistematika (2007 Moscow, Russia). Vychislitelʹnai︠a︡ filogenetika i genosistematika "VFGS'2007" : K 50-letii︠u︡ stanovlenii︠a︡ otechestvennoĭ filogenetiki i genosistematiki : materialy mezhdunarodnoĭ konferent︠s︡ii, 16-19 noi︠a︡bri︠a︡ 2007 g., g. Moskva = Computational phylogenetics and molecular systematics "CPMS' 2007" : commemorating the 50th anniversary of Molecular Phylogenetics and Systematics in Russia conference proceedings, November 16-19, 2007, Moscow, Russia. Moskva : T-vo nauch. izdaniĭ KMK, 2007.
Trouver le texte intégralVychislitelʹnai︠a︡ filogenetika i genosistematika (2007 Moscow, Russia). Vychislitelʹnai︠a︡ filogenetika i genosistematika "VFGS'2007" : K 50-letii︠u︡ stanovlenii︠a︡ otechestvennoĭ filogenetiki i genosistematiki : materialy mezhdunarodnoĭ konferent︠s︡ii, 16-19 noi︠a︡bri︠a︡ 2007 g., g. Moskva = Computational phylogenetics and molecular systematics "CPMS' 2007" : commemorating the 50th anniversary of Molecular Phylogenetics and Systematics in Russia conference proceedings, November 16-19, 2007, Moscow, Russia. Moskva : T-vo nauch. izdaniĭ KMK, 2007.
Trouver le texte intégralInternational Conference of Mathematical Modeling and Computational Experiments (3rd 2002 Dushanbe, Tajikistan). Materialy 3-eĭ Mezhdunarodnoĭ konferent︠s︡ii po matematicheskomu modelirovanii︠u︡ i vychislitelʹnomu ėksperimentu, Dushanbe, 10-12 dekabri︠a︡ 2002 g. = Tajik State National University : proceedings of the 3rd International Conference of Mathematical Modeling and Computational Experiments, Dushanbe,December 10-12, 2002. Dushanbe : Tadzhikskiĭ gos. natsional'nyĭ universitet, 2002.
Trouver le texte intégralAdamatzky, Andrew. Emergent Computation : A Festschrift for Selim G. Akl. Springer, 2016.
Trouver le texte intégralAdamatzky, Andrew. Emergent Computation : A Festschrift for Selim G. Akl. Springer, 2018.
Trouver le texte intégralAdamatzky, Andrew. Emergent Computation : A Festschrift for Selim G. Akl. Springer International Publishing AG, 2016.
Trouver le texte intégralEnright, Brian E. Fractions, Decimals : Teachers Guide/Books E,F,G,L,M (Enright Computation Series, Th789). Curriculum Associates Inc, 1986.
Trouver le texte intégralBausch, Win. OPERA-G : A microkernel for computational grids. 2004.
Trouver le texte intégralGuide : Guide for the Verification and Validation of Computational Fluid Dynamics Simulations (AIAA G-077-1998(2002)). Washington, DC : American Institute of Aeronautics and Astronautics, Inc., 1998. http://dx.doi.org/10.2514/4.472855.
Texte intégralChapitres de livres sur le sujet "G-Computation"
Romero, G., M. G. Arenas, J. G. Castellano, P. A. Castillo, J. Carpio, J. J. Merelo, A. Prieto et V. Rivas. « Evolutionary Computation Visualization : Application to G-PROP ». Dans Parallel Problem Solving from Nature PPSN VI, 902–12. Berlin, Heidelberg : Springer Berlin Heidelberg, 2000. http://dx.doi.org/10.1007/3-540-45356-3_88.
Texte intégralChakraborty, Bibhas, et Erica E. M. Moodie. « G-computation : Parametric Estimation of Optimal DTRs ». Dans Statistical Methods for Dynamic Treatment Regimes, 101–12. New York, NY : Springer New York, 2013. http://dx.doi.org/10.1007/978-1-4614-7428-9_6.
Texte intégralHaqiqi, Iman, et Uris Lantz C. Baldos. « Computation and Baseline : Efficient Methods for Solving a Large System of Equations for Projection and Scenario Analysis ». Dans SIMPLE-G, 103–11. Cham : Springer Nature Switzerland, 2024. http://dx.doi.org/10.1007/978-3-031-68054-0_8.
Texte intégralFikioris, George. « Generalized Hypergeometric Functions, Meijer G-Functions, and Their Numerical Computation ». Dans Mellin-Transform Method for Integral Evaluation, 17–20. Cham : Springer International Publishing, 2007. http://dx.doi.org/10.1007/978-3-031-01697-4_3.
Texte intégralHerrmann, Christoph. « Efficient Computation of Waiting Time Moments for the DBMAP/G/1/N Queue ». Dans IFIP Advances in Information and Communication Technology, 481–96. Boston, MA : Springer US, 2000. http://dx.doi.org/10.1007/978-0-387-35353-1_24.
Texte intégralCornelissen, Gunther, et Norbert Peyerimhoff. « Examples of Homologically Wide Actions ». Dans Twisted Isospectrality, Homological Wideness, and Isometry, 73–83. Cham : Springer International Publishing, 2023. http://dx.doi.org/10.1007/978-3-031-27704-7_9.
Texte intégralRomero, Jazmín, et Alejandro López-Ortiz. « The ${\mathcal{G}}$ -Packing with t-Overlap Problem ». Dans Algorithms and Computation, 114–24. Cham : Springer International Publishing, 2014. http://dx.doi.org/10.1007/978-3-319-04657-0_13.
Texte intégralDvořák, Zdeněk, et Vít Jelínek. « On the Complexity of the G-Reconstruction Problem ». Dans Algorithms and Computation, 196–205. Berlin, Heidelberg : Springer Berlin Heidelberg, 2005. http://dx.doi.org/10.1007/11602613_21.
Texte intégralZhu, Xin-jie. « A Finite Spectrum Unmixing Set For \mathcal{G}\mathcal{L}{\text{(3,}}\mathcal{R}{\text{)}} ». Dans Computation and Control, 403–10. Boston, MA : Birkhäuser Boston, 1989. http://dx.doi.org/10.1007/978-1-4612-3704-4_30.
Texte intégralLi, Quan-Lin. « Markov Chains of GI/G/1 Type ». Dans Constructive Computation in Stochastic Models with Applications, 131–75. Berlin, Heidelberg : Springer Berlin Heidelberg, 2010. http://dx.doi.org/10.1007/978-3-642-11492-2_3.
Texte intégralActes de conférences sur le sujet "G-Computation"
Alsunaidi, Abdullah, Safwat Abdel-Azeim, C. Richard Catlow, Alexey Sokols et Scott Woodley. « Charge Transfer in the Fe/g-C3N4/MoS2 Heterojunction : A Computational Study ». Dans 2024 IEEE 14th International Conference Nanomaterials : Applications & ; Properties (NAP), 1–4. IEEE, 2024. http://dx.doi.org/10.1109/nap62956.2024.10739735.
Texte intégralSpera, Emiliano, Giovanni Gallo, Dario Allegra, Filippo Stanco, Andrea Maugeri, Annalisa Quattrocchi, Martina Barchitta et Antonella Agodi. « Randomized G-Computation Models in Healthcare Systems ». Dans 2018 IEEE 31st International Symposium on Computer-Based Medical Systems (CBMS). IEEE, 2018. http://dx.doi.org/10.1109/cbms.2018.00021.
Texte intégralWang, Changping, Chaokun Wang, Gaoyang Guo, Xiaojun Ye et Philip S. Yu. « Efficient Computation of G-Skyline Groups (Extended Abstract) ». Dans 2018 IEEE 34th International Conference on Data Engineering (ICDE). IEEE, 2018. http://dx.doi.org/10.1109/icde.2018.00242.
Texte intégralZacharewicz, G., N. Giambiasi et C. Frydman. « Improving the lookahead computation in G-DEVS/HLA environment ». Dans DS-RT 2005 Proceedings. Ninth IEEE International Symposium on Distributed Simulation and Real-Time Applications. IEEE, 2005. http://dx.doi.org/10.1109/distra.2005.24.
Texte intégralZhang, Jie, Yan Chen, Xiang Hu, Jiwei Hu et Lintao Yang. « G-Computation Demonstration in Causal Mediation Analysis with Multiple Mediators ». Dans 2022 IEEE 2nd International Conference on Software Engineering and Artificial Intelligence (SEAI). IEEE, 2022. http://dx.doi.org/10.1109/seai55746.2022.9832193.
Texte intégralLiu, Fuhao, Yongmin Shuai, Xin Zhang, Yunfei Xiong et Yong Zeng. « G-Computation Demonstration in Estimating Causal Effects with Time-Dependent Confounding ». Dans 2022 IEEE 2nd International Conference on Software Engineering and Artificial Intelligence (SEAI). IEEE, 2022. http://dx.doi.org/10.1109/seai55746.2022.9832345.
Texte intégralSpitler, Jeffrey, et Jack Cook. « Faster computation of g-functions used for modeling of ground heat exchangers ». Dans 2021 Building Simulation Conference. KU Leuven, 2021. http://dx.doi.org/10.26868/25222708.2021.31086.
Texte intégralBean, Andrew, Nachiket Kapre et Peter Cheung. « G-DMA : improving memory access performance for hardware accelerated sparse graph computation ». Dans 2015 International Conference on ReConFigurable Computing and FPGAs (ReConFig). IEEE, 2015. http://dx.doi.org/10.1109/reconfig.2015.7393317.
Texte intégralAmiri, Neda Kazemian, Sied Mehdi Fakhraie, Gholam-Ali Hosein-Zadeh et Sied Mahmoud Mousavinejad. « Modeling of ITU-T G.729 codec with bit-width optimization for intensive computation blocks ». Dans 2007 International Conference on Microelectronics - ICM. IEEE, 2007. http://dx.doi.org/10.1109/icm.2007.4497659.
Texte intégralJin, Yue, Chengying Huan, Heng Zhang, Yongchao Liu, Shuaiwen Leon Song, Rui Zhao, Yao Zhang, Changhua He et Wenguang Chen. « G-Sparse : Compiler-Driven Acceleration for Generalized Sparse Computation for Graph Neural Networks on Modern GPUs ». Dans 2023 32nd International Conference on Parallel Architectures and Compilation Techniques (PACT). IEEE, 2023. http://dx.doi.org/10.1109/pact58117.2023.00020.
Texte intégralRapports d'organisations sur le sujet "G-Computation"
Smith, Bradley W. Distributed Computing for Signal Processing : Modeling of Asynchronous Parallel Computation. Appendix G. On the Design and Modeling of Special Purpose Parallel Processing Systems. Fort Belvoir, VA : Defense Technical Information Center, mai 1985. http://dx.doi.org/10.21236/ada167622.
Texte intégralBryan Sallee, Colleen E. Characterization of Reference Material 8210 :. Gaithersburg, MD : National Institute of Standards and Technology, 2024. http://dx.doi.org/10.6028/nist.sp.260-248.
Texte intégralTow Leong, Tiang, Mohd Saufi Ahmad, Ang Qian Yee, Syahrun Nizam Md Arshad@Hashim, Mohd Faizal Mohd Zahir, Mohd Azlizan Moh Adib, Nazril Husny, Tan Kheng Kwang et Dahaman Ishak. HANDBOOK OF ELECTRICAL SYSTEM DESIGN FOR NON-DOMESTIC BUILDING. Penerbit Universiti Malaysia Perlis, 2023. http://dx.doi.org/10.58915/techrpt2023.001.
Texte intégralVold, E. Synopsis of some preliminary computational studies related to unsaturated zone transport at Area G. Office of Scientific and Technical Information (OSTI), mars 1998. http://dx.doi.org/10.2172/650172.
Texte intégralShukla, Manoj K., Luidmyla K. Sviatenko, Sergly I. Okovytyy, Danuta Leszczynska et Jerzy Leszczynski. Catalytic Role of Solvated Electron in the Spontaneous Degradation of Insensitive Munition Compounds : Computational Chemistry Investigation. Engineer Research and Development Center (U.S.), juillet 2021. http://dx.doi.org/10.21079/11681/41122.
Texte intégralBorgwardt, Stefan, Felix Distel et Rafael Peñaloza. Gödel Description Logics : Decidability in the Absence of the Finitely-Valued Model Property. Technische Universität Dresden, 2013. http://dx.doi.org/10.25368/2022.199.
Texte intégralKotliar, Gabriel. Final Report of the CMSN team working on computational-design-Fe-based-superconductors ( 8/31/10-8/31/13). Team Leader G. Kotliar Rutgers University. (DE-SC0005468). Office of Scientific and Technical Information (OSTI), novembre 2014. http://dx.doi.org/10.2172/1163667.
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