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Articles de revues sur le sujet "FZ. None of these, but in this section"
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Lv, Hang, Guoqing Gou, Zhenghong Fu et Wei Gao. « Stress corrosion property of 304 stainless steel and Q345 steel laser-MAG hybrid welded joints ». International Journal of Modern Physics B 34, no 01n03 (19 décembre 2019) : 2040057. http://dx.doi.org/10.1142/s0217979220400573.
Texte intégralRésumé :
The stress corrosion cracking (SCC) property of laser-MAG hybrid welded 304 stainless steel and Q345 steel was evaluated through cycle-immersion testing in 3.5 wt.% NaCl solution. The average SCC crack propagation rate of different zones under different initial stress intensity factors was calculated, and the SCC fracture and crack propagation path were observed. The microstructure and mechanical properties of the weld joint have also been examined. The result indicates that the fusion zone (FZ) is extremely prone to SCC. The average SCC crack propagation rate in FZ is [Formula: see text] mm/h, while no obvious SCC was found in the base metal (BM) and heat-affected zone (HAZ). The steel BM and HAZ may also suffer SCC, but not as fast as in FZ. Grooves caused by SCC were found on the fracture surface with a large amount of corrosion products accumulated close to the interface between the pre-crack section and SCC section. Crystallized-sugar-shaped pattern was found on the SCC zone of FZ. Crack jumping, deflection and crack closure occurred in the crack propagation path. Martensite on the FZ was considered to be the major reason that the FZ has a higher SCC propagation rate.
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Al-Shammary, Maha, Zaid Malak et Mudher Al-Jwary. « Sedimentological Study of Exposed Successions of the Sargelu Formation, Middle Jurassic, Northeastern, Iraq ». Iraqi Geological Journal 56, no 1B (28 février 2023) : 51–63. http://dx.doi.org/10.46717/igj.56.1b.5ms-2023-2-13.
Texte intégralRésumé :
The Middle Jurassic Sargelu Formation spreads out widely in North-Eastern Iraq, particularly within the High Folds Unstable Shelf Zone. The Sargelu Formation was studied in two exposed sections, Hanjira and Gorin, in the Northeastern part of Iraq. The Lower contact of the formation with the Sehkaniyan Formation and the Upper contact with the Naokelekan Formation in the two sections appears conformable. The thickness of the Formation in the Hanjira section is 40m. and in the Gorin section is 70 m. The sampling was done by taking samples from two sections and thin sections were made for all samples and were studied under a polarizing microscope. Three main microfacies donated as M, W, P, and eight submicrofacies were diagnosed which reflects the deposition of the formation within the FZ-1 zone known as the Deep Sea Basin and the FZ-2 known as the Deep Shelf.
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Zenkner-Neto, Alfredo, Waldemir Vieira-Junior, Flávia Amaral, Fabiana França, Roberta Basting et Cecilia Turssi. « Bulk-fill restorative composites under simulated carious and erosive conditions ». Acta Odontológica Latinoamericana 35, no 2 (29 septembre 2022) : 111–19. http://dx.doi.org/10.54589/aol.35/2/111.
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Acidic conditions can cause hydrolysis and accelerate degradation of resin composites (RCs). Since there are limited and controversial data on the effect of acids on bulk-fill RCs, this study assessed the surface roughness (SR) and flexural strength (FS) of these RCs under simulated carious and erosion conditions. Bars of Filtek Bulk Fill (FBF, 3M/ESPE), X-tra fil (XTF, Voco), Tetric N-Ceram Bulk Fill (TBF, Ivoclar/Vivadent), and Aura Bulk Fill (ABF, SDI) and a conventional RC [Filtek Z350XT (FZ, 3M/ESPE)] were allocated (n=15) to undergo caries or erosion conditions. The control group was kept in artificial saliva (AS). The bars were evaluated for SR change (final-baseline) and for three-point FS. Data were analyzed using ANOVA and Tukey’s test. At the baseline (p < 0.001), the SR of RCs ranked as follows: (TBF = XTF) < FBF (none differed from FZ) < ABF. The interplay between RCs and conditions affected SR change (p = 0.025). While after storage in AS, there was no difference among RCs, following carious and erosive conditions, ABF showed higher SR change. For FS (p < 0.001), XTF > (FBF = FZ) > (TBF = FZ) > ABF, with no difference among control, carious and erosive conditions (p = 0.148). Depending on the restorative bulk-fill RCs, carious and erosive conditions roughen the surface but do not affect the FS of these materials.
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Stadtmauer, Edward A., David Siegel, Dan T. Vogl, James Stinnett, Geetha Narayanan, P. P. Bapsy, Trivadi Ganesan et al. « A Phase 1 Trial of Fluphenazine HCl (Fz), a Serotonin Antagonist, in Relapsed and Refractory Multiple Myeloma ». Blood 112, no 11 (16 novembre 2008) : 5188. http://dx.doi.org/10.1182/blood.v112.11.5188.5188.
Texte intégralRésumé :
Abstract Background: Serotonin (5-HT) is a lymphocyte growth factor, and lymphocytes bear 5-HT receptors. Fz has anti-serotonergic properties and a favorable safety profile. Fz inhibits growth of Jurkat leukemia cells at concentrations of 1–10 μM (Schleuning M et al, Anticancer Research 1993;13:599–602). Other serotonin receptor antagonists have been shown to have in vitro and pre-clinical in vivo anti-myeloma effects mainly mediated by apoptosis (Ocio EM, et al, Blood 2006 108:Abs 2597). In vitro studies show 10μM Fz exposure for 18hr kills many myeloma and leukemic cell lines, while sparing non-activated, normal, human lymphocytes. In rat studies, Fz partitions into bone marrow (BM) 100× more avidly than into blood. Fz was thus selected for a proof of concept phase 1 trial in patients (pts) with previously treated myeloma. Methods: Pts with myeloma had failed at least 2 prior regimens; had measurable serum or urine M-proteins, or skewed free light chain ratio per central lab assay; had adequate organ function and performance status (ECOG <3); and were not on selective serotoin reuptake inhibitors (SSRIs), tricyclic, or norepinephrine reuptake inhibitor drugs or other anti-serotonergic agents. Fz was given i.v. in a dose escalating “3+3 design” in three divided 5-minute injections at 0, 6, and 12 hrs once every 28 days. Total Fz doses per 3-bolus exposure were 0.11, 0.23, 0.34, 0.57, 0.80, and 1.14 mg/kg. Serum samples for Fz PK analysis were collected from all patients during cycle 1. A single (time-paired with a serum PK sample) BM biopsy for BM Fz level was obtained from a subset of pts. Results: 21 pts (13M; 8F) from 7 sites in the U.S. and India, median age 55 yrs (range 30–75) were enrolled, 3 pts were enrolled per dose cohort, except for 6 pts at 0.34 mg/kg. Median number prior regimens was 4; 15/21 had prior thalidomide or lenalidomide or both; 10/21 had prior bortezomib; 8/21 had prior stem cell transplant (including 2 with tandem transplant, 1 had a third salvage transplant). A MTD was not reached. One DLT, grade 3 extra-pyramidal reaction (EPR) of acute dystonia with stiff jaw, occurred at 0.34 mg/kg. Six pts experienced EPR (4M; 2F) typically occurring 30–36 hrs post first dose; intensity and frequency were not dose related. All EPR except the 1 DLT were grade 1 or 2. Fifteen serious adverse events (SAEs) occurred in 10 pts, all assessed as unrelated to Fz. The most common ≥ gr 3 non-serious AEs were anemia, thrombocytopenia, and back pain, none of which was assessed as related to Fz. All cases of orthostatic hypotension, agitation, EPR, sedation, somnolence, and 3 of 4 cases of fatigue were deemed related to Fz. Comparison of time-paired BM and serum Fz concentrations in 6 pts showed 4–77-fold higher Fz levels in the marrow over serum in the first 49 hrs post-dosing. The best response through 2 cycles of treatment per Blade criteria in 19 evaluable pts was stable disease in 3 pts (0.23, 0.34, and 0.80 mg/kg; duration 2, 5, and 6 cycles). Conclusion: Fluphenazine may be safely given to pts with relapsed and refractory myeloma at the doses and schedule described, with EPR and sedation that are generally mild and manageable. Fz partitions 1–2 log greater into human BM compared with serum. A MTD was not reached, and additional studies are planned with more dose-intensive schedules.
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Muñoz, Jairo Alberto, Egor Dolgach, Vanina Tartalini, Pablo Risso, Martina Avalos, Raúl Bolmaro et José María Cabrera. « Microstructural Heterogeneity and Mechanical Properties of a Welded Joint of an Austenitic Stainless Steel ». Metals 13, no 2 (27 janvier 2023) : 245. http://dx.doi.org/10.3390/met13020245.
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This research presents the microstructural and mechanical evolution throughout the welded seam of an austenitic stainless steel (ASS) tube. It was found that the main hardness decrement occurred in the fusion zone (FZ), followed by the heat-affected zone (HAZ) and the base material (BM). Optical microscopy indicated a dendritic structure in FZ and heterogeneous austenitic grain size from the HAZ towards the BM, ranging from 100 µm to 10 µm. The welding process generated an intense texture around the FZ and the HAZ, while the BM still showed an extrusion-like texture. In terms of mechanical behavior, the largest austenite grain size in the FZ led to the lowest strength and ductility of all zones due to the earliest strain localization manifested by heterogeneous strain distribution. However, the strain localization in all zones appeared after 0.4 true strain, indicating an overall good ductility of the seam. These high values were related to two microstructure characteristics: 1) the 10% δ-ferrite after solidification in the FZ favored by the Creq/Nieq = 1.67 relationship that delayed the crack propagation along the austenite grains and 2) the heterogeneous microstructure made up of soft austenite and hard martensite in the HAZ and BM producing multiple strain concentrations. Kernel Average Misorientation (KAM) maps obtained by Electron Back-Scattering Diffraction (EBSD) allowed observing higher internal misorientations in the FZ than in the HAZ due to interconnected walls between the δ-ferrite grains. However, the largest KAM values were observed in the BM between γ-austenite and the deformation-induced α’-martensite phases. X-ray diffraction revealed that the residual stresses in the cross-section of the welded seam were compression-type and then switched to tension-type in the outer surface.
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Huang, Guangyao, Liang Yang, Wei Zhou, Xianglin Tang, Yuguang Wang, Zengchun Ma, Shan Gao et Yue Gao. « Study on Cardiotoxicity and Mechanism of “Fuzi” Extracts Based on Metabonomics ». International Journal of Molecular Sciences 19, no 11 (7 novembre 2018) : 3506. http://dx.doi.org/10.3390/ijms19113506.
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To investigate the toxicity of water and ethanol “Fuzi” (FZ) extracts and to explore the toxicity mechanism in rats. Water and ethanol extracts were prepared. Three groups of rats received the water extract, ethanol extract, or water by oral gavage for seven days. Pathological section staining of heart tissue. Colorimetric analysis was used to determine serum lactate dehydrogenase. The metabolic expression of small molecules in rats was measured by a metabolomics method. Western blotting was used to detect the expression of phosphoinositide 3-kinase (PI3K), protein kinase B (Akt), mammalian target of rapamycin (mTOR), transforming growth factor-β1 (TGF-β1), and caspase-3. Immunohistochemistry was used to detect the expression of CTnI, mTOR, and TGF-β1. The water and ethanol FZ extracts exert cardiotoxic effects via activating the PI3K/Akt/mTOR signaling pathway to induce cardiomyocyte apoptosis.
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Kundrák, János, Tamás Makkai et István Deszpoth. « Effect of Cutting Feed and Chip Size Ratio on Cutting Force ». Solid State Phenomena 261 (août 2017) : 3–8. http://dx.doi.org/10.4028/www.scientific.net/ssp.261.3.
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In producing parts, besides increasing accuracy and maintaining/improving the cut surface quality, the main effort of the manufacturers is to improve the productivity/profit. In face milling this aim can be achieved first of all by increasing cutting speed and feed. The importance of feed impact analysis is justified by the general effort to prefabricate parts near net shape, if possible by one pass material removal. If the manufacturing is done by one pass, the surface rate (Aw, mm2/min) can be increased by the increase of feed. It fz feed is increased, the feed per tooth (keeping ap at constant value) ap/fz ratio is changed and as a consequence also the load on cutting edges and the character of chip deformation. The increase in the feed and the change in the chip cross section shape influence the cutting forces and the efficiency. In this paper, the changes in the cutting force components with different feed rates are demonstrated, while the value of the feed is increased 16-fold.
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Андреев, Владимир, et Vladimir Andryeyev. « Nature of Intangible Benefits and Their Protection ». Journal of Russian Law 2, no 3 (26 février 2014) : 27–33. http://dx.doi.org/10.12737/2577.
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In article according to standards of the Federal law of July 2, 2013 No. 142-FZ “On modification of subsection 3 of the section I of part one of the Civil Code of the Russian Federation” are studied a being of the intangible benefits and their protection. Properties of the intangible benefit as right subject form of the person and citizen, other than a common property right are established. Classification of the intangible benefits is given, specific ways of their protection are considered.
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M. Salleh, M. N., M. Ishak, M. H. Aiman, M. M. Quazi et A. M. Hanafi. « Weld Geometry Investigation on Dissimilar Boron Steel Laser Welded for TWB Application ». International Journal of Automotive and Mechanical Engineering 16, no 4 (30 décembre 2019) : 7364–74. http://dx.doi.org/10.15282/ijame.16.4.2019.12.0546.
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The pulse wave (PW) mode is an excellent replacement for continuous wave (CW) mode f laser welding in the tailor-welded blank (TWB) application for the automotive ndustry. Due to its ability to produce higher peak power in low power laser pulse mode, he weld penetration and high weld quality can be achieved similarly to the utilization of very high power laser of CW mode. This present work was carried out to investigate the ffect of pulse laser welding parameters of a dissimilar thickness of boron steel for the TWB application. Low power fibre laser with 200 W average power was chosen in this xperimental work. Response surface method (RSM) was used for the design of xperiment (DOE) by applying Box-behnken design (BBD) since there were three rocess factors involved. The process factors are peak power (PP), welding speed (WS) nd focal position (FP) and tensile strength is the response for the weld joint. The metallurgical analysis was conducted at the cross section of sample possessing highest nd lowest tensile strength. Boron steel was successfully welded by using low power fibre aser with PW mode in butt joint configuration. It was found that the highest tensile trength possessed fracture located at the base metal, which is convincing the strength of he joint. For microstructure, finer grain produced at the centre of the fusion zone (FZ) ompared to the FZ near the transition line which produced coarser and medium grain. Finer grain size in FZ contributes to the higher microhardness value and tensile strength f the joint compared to the BM region.
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Л.М., Верещагина,. « Standards for designing systems for the removal and treatment of surface runoff and unsettled requirements of the water protection legislation ». Vodosnabzhenie i sanitarnaia tehnika, no 1 (16 janvier 2023) : 19–25. http://dx.doi.org/10.35776/vst.2023.01.03.
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Рассматривается нормативно-правовое регулирование проектирования инженерных сооружений систем отведения и очистки поверхностных сточных вод поселений и законодательно неурегулированные положения действующего свода правил СП 32.13330. 2018 «СНиП 2.04.03-85 «Канализация. Наружные сети и сооружения» (с изменениями № 1 и 2) по разделу «Отведение и очистка поверхностных сточных вод». Приводятся предложения по внесению изменений в статью 60 Водного кодекса РФ № 74-ФЗ и статью 16 Федерального закона № 7-ФЗ «Об охране окружающей среды», учитывающие специфические особенности образования и условия отведения поверхностных сточных вод в централизованные системы водоотведения и водные объекты. The statutory regulation of designing engineering structures of the systems for the removal and treatment of surface runoff in communities, and the legislatively unsettled provisions of the current Code of Practice CP 32.13330.2018 «SNiP 2.04.03-85 «Sewerage. Pipelines and wastewater treatment plants» (with amendments No. 1 and 2) of the section «Removal and treatment of surface runoff» are considered. Proposals are made to introduce amendments to Article 60 of the Water Code of the Russian Federation No. 74-FZ and Article 16 of the Federal Law No. 7-FZ «On the Environmental Protection», with account of the specific features of the formation and conditions for the discharge of surface runoff into the public wastewater disposal systems and water bodies.
Thèses sur le sujet "FZ. None of these, but in this section"
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Lubisco, Nídia Maria Lienert. « La evaluación en la biblioteca universitaria brasileña : evolución y propuesta de mejora ». Thesis, Universidad Carlos III De Madrid, 2007. http://eprints.rclis.org/12225/1/tesisnidia.pdf.
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This thesis examines the evolution of the evaluation of the university library in Brazil. At present, the only applicable system takes place in the evaluation of academic by the Ministry of Education, through the National Institute for Studies and Research Educacionais Anísio Teixeira (INEP), the entity responsible for coordinating and implementing the process of evaluating the entire education system in Brazil. The starting point for addressing this investigation were the results of a case study developed at the Federal University of Bahia in 2001, under the assumption that the Ministry did not have criteria and appropriate instruments to reflect the library's role as a resource for educational qualifications. The review of the literature relevant Brazilian, British and Spanish regarding the subject, especially regarding experience with the Spanish University Libraries Network (REBIUN), were essential to know the trends and the state of affairs. It also took out a field work through questionnaires in 7 countries and 31 Latin American universities, in order to ascertain the current status of evaluation systems used in that region. The low response rate, about 50% of institutions surveyed, this was offset by the work of the Symposium on Electronic Library evaluator and Quality (Sociedad Argentina de report, 2002), an event of great significance to who came over 450 librarians and teachers. This initiative helped develop a comparative study that served to place the Brazilian reality and take into account the most similar case mix. All this enabled comply with the overall objective of this thesis: develop a model to evaluate university libraries in Brazil, from the state of affairs of the university library and Brazilian experiences located in Latin American countries. That model se basa en el Instrument INEP (2006), but its content is raised, taking into account different jobs: performance indicators for assessing the university library, REBIUN (2000), one of the documents PNBU, prepared Romcy by Maria Carmen de Carvalho (1995), Standards for university libraries in Chile (2001) and methodological guide for evaluating the libraries of institutions of higher education (Mexico, 2000). The final claim is that the Brazilian Ministry has a more comprehensive evaluation system, to be implemented and improved according to the data you make and, in turn, could be to build a bank of information management and a system of indicators performance.
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Ollendorff, Christine. « Construction d'un diagnostic complexe d'une bibliothèque académique ». Thesis, Ecole nationale supérieure d'arts et métiers - ENSAM, 1999. http://eprints.rclis.org/11682/1/These-co.pdf.
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In the first part, we studies academic libraries whose founding principles are change with the information society. The library manager looks for the best ways to lead a library. Evaluation and management tools on libraries are sources of insatisfactions because of the lack of a holistic vision of libraries they give. Constructivist approaches of management seems an alternative way to help library managers in designing a strategic vision of these organizations. In the second part, we build a modelization project with complex systems modelization of Jean-Louis Le Moigne and soft systems methodology of Peter Checkland. French academic libraries constitute our research field in which we use participant observations and staff and managers interviews. Our system is made up of the academic library in the vision of it leader. We build a three phase diagnostic. With the first phase, the manager can observ services supply as a three axes system which evolves with technologies, materials and humans means and bibliotheconomic knowledge. The second phase studies the informational system with environmental and flow observations. The third phase studies the decisional system, looking for its organization, ist internal information circulation and its decisional processes. This diagnostic is in continuous construction. It works in the library management continuity and is not the first step of a strategic planning. We use the diagnostic in five libraries. Results show modelization supply with the creation of evolving, transposable and learning models.
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Ebenezer, Catherine. « “Access denied” ? Barriers for staff accessing, using and sharing published information online within the National Health Service (NHS) in England : technology, risk, culture, policy and practice ». Thesis, University of Sheffield, 2017. http://eprints.rclis.org/32585/1/CME%20thesis%20v4.0%20White%20Rose%20final%20single%20volume.pdf.
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The overall aim of the study was to investigate barriers to online professional information seeking, use and sharing occurring within the NHS in England, their possible effects (upon education, working practices, working lives and clinical and organisational effectiveness), and possible explanatory or causative factors.
The investigation adopted a qualitative case study approach, using semi-structured interviews and documentary analysis as its methods, with three NHS Trusts of different types (acute - district general hospital, mental health / community, acute – teaching) as the nested sites of data collection. It aimed to be both exploratory and explanatory. A stratified sample of participants, including representatives of professions whose perspectives were deemed to be relevant, and clinicians with educational or staff development responsibilities, was recruited for each Trust. Three non-Trust specialists (the product manager of a secure web gateway vendor, an academic e-learning specialist, and the senior manager at NICE responsible for the NHS Evidence electronic content and web platform) were also interviewed. Policy documents, statistics, strategies, reports and quality accounts for the Trusts were obtained via public websites, from participants or via Freedom of Information requests. Thematic analysis following the approach of Braun and Clarke (2006) was adopted as the analytic method for both interviews and documents. The key themes of the results that emerged are presented: barriers to accessing and using information, education and training, professional cultures and norms, information governance and security, and communications policy.
The findings are discussed under three main headings: power, culture, trust and risk in information security; use and regulation of Web 2.0 and social media, and the system of professions. It became evident that the roots of problems with access to and use of such information lay deep within the culture and organisational characteristics of the NHS and its use of IT. A possible model is presented to explain the interaction of the various technical and organisational factors that were identified as relevant. A number of policy recommendations are put forward to improve access to published information at Trust level, as well as recommendations for further research.
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Boyer, Sebastien. « Dans le cadre du nouveau cycle de combustible $^(232)$Th/$^(233)$U, determination de la section efficace de capture radiative $^(233)$Pa(n,$\gamma$) pour des energies de neutrons comprises entre 0 et 1 MeV ». Phd thesis, Université Sciences et Technologies - Bordeaux I, 2004. http://tel.archives-ouvertes.fr/tel-00009062.
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Dans l'optique d'un developpement durable du nucleaire, un des themes de recherche du CNRS dicte par la loi Bataille de 1991, est l'etude d'une nouvelle filiere nucleaire utilisant un combustible a base de minerai de thorium ($^(232)$Th) ou le noyau fissile est l'$^(233)$U. Le principal interet de ce type de combustible reside dans sa particularite de produire les dechets transuraniens en beaucoup plus faible quantite que les reacteurs a eau pressurisee actuels. Cependant certaines donnees nucleaires importantes concernant cette nouvelle filiere sont tres mal connues comme par exemple celles relatives au noyau charniere protactinium 233 ($^(233)$Pa). Sa periode de 27 jours lui confere un role particulier dans le cycle mais en raison de sa trop forte activite l'etude de ce noyau releve du defi experimental. Pour contourner cette difficulte, la probabilite d'emission de rayonnements gamma dans la reaction induite par neutrons $^(233)$Pa(n,$\gamma$) entre 0 et 1 MeV d'energie neutron a ete determinee a partir de la reaction transfert $^(232)Th(^(3)He,p)^(234)Pa*$. Le dispositif de mesure permettait d'identifier la particule de sortie signant ainsi la voie de reaction tandis que des scintillateurs de type C$_(6)$D$_(6)$ permettaient la detection en coincidence des rayonnements gamma emis. La methode d'analyse des evenements gamma a necessite la ponderation des spectres de photons par des fonctions mathematiques calculees dites "fonctions de poids". leurs determinations requierent neanmoins une connaissance parfaite du comportement des scintillateurs (efficacite, fonctions de reponse) dans la geometrie choisie. Pour ce faire, une etude preliminaire a ete realisee a l'aide de sources gamma et avec des reactions induites par protons sur des noyaux legers. Les simulations utilisant le code de transport MCNP ont ete validees par des resultats experimentaux.
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Park, Allison M. « Comparing the Cognitive Demand of Traditional and Reform Algebra 1 Textbooks ». Scholarship @ Claremont, 2011. http://scholarship.claremont.edu/hmc_theses/9.
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Research has shown that students achieved higher standardized test scores in mathematics and gained more positive attitudes towards mathematics after learning from reform curricula. Because these studies involve actual students and teachers, there are classroom variables that are involved in these findings (Silver and Stein, 1996; Stein et al., 1996). To understand how much these curricula by themselves contribute to higher test scores, I have studied the cognitive demand of tasks in two traditional and two reform curricula. This work required the creation of a scale to categorize tasks based on their level of cognitive demand. This scale relates to those by Stein, Schoenfeld, and Bloom. Based on this task analysis, I have found that more tasks in the reform curricula require higher cognitive demand than tasks in the traditional curricula. These findings confirm other results that posing tasks with higher cognitive demand to students can lead to higher student achievement.
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Zurita, Sánchez Juan Manuel. « El paradigma otletiano como base de un modelo para la organización y difusión del conocimiento científico ». Thesis, Universidad Nacional Autónoma de México, 2001. http://eprints.rclis.org/6752/1/tesina._juan_manuel_zurita.pdf.
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Cho, Karina Elle. « Enhancing the Quandle Coloring Invariant for Knots and Links ». Scholarship @ Claremont, 2019. https://scholarship.claremont.edu/hmc_theses/228.
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Quandles, which are algebraic structures related to knots, can be used to color knot diagrams, and the number of these colorings is called the quandle coloring invariant. We strengthen the quandle coloring invariant by considering a graph structure on the space of quandle colorings of a knot, and we call our graph the quandle coloring quiver. This structure is a categorification of the quandle coloring invariant. Then, we strengthen the quiver by decorating it with Boltzmann weights. Explicit examples of links that show that our enhancements are proper are provided, as well as background information in quandle theory.
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Mebane, Palmer. « Uniquely Solvable Puzzles and Fast Matrix Multiplication ». Scholarship @ Claremont, 2012. https://scholarship.claremont.edu/hmc_theses/37.
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In 2003 Cohn and Umans introduced a new group-theoretic framework for doing fast matrix multiplications, with several conjectures that would imply the matrix multiplication exponent $\omega$ is 2. Their methods have been used to match one of the fastest known algorithms by Coppersmith and Winograd, which runs in $O(n^{2.376})$ time and implies that $\omega \leq 2.376$. This thesis discusses the framework that Cohn and Umans came up with and presents some new results in constructing combinatorial objects called uniquely solvable puzzles that were introduced in a 2005 follow-up paper, and which play a crucial role in one of the $\omega = 2$ conjectures.
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Moreira, Walter. « A construção de informações documentárias : aportes da linguística documentária, da terminologia e das ontologias ». Thesis, Universidade de São Paulo, 2010. http://eprints.rclis.org/17437/1/TeseFinalRevisada_05Jul2010.pdf.
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Investigates theoretical and practical interfaces between terminology, philosophical
ontology, computational ontology and documentary linguistics and the subsidies that they offer for the construction of documentary information. It was established as specific objectives, the analysis of the production, development, implementation and use of ontologies based on the information science theories, the research on the contribution of ontologies for the development of thesauri and vice versa and the discussion of the philosophical foundation of the application of ontologies based on the study of ontological categories present in classical philosophy and in the contemporary proposals. It argues that the understanding of ontologies through the communicative theory of terminology contributes to the organization of a less quantitative access (syntactic) and more qualitative (semantic) of information. Notes that, in spite of sharing some common goals, there is little dialogue between the information science (and, inside it, the documentary linguistics) and computer science. It argues that the computational and philosophical ontologies are not
completely independent events, which have among themselves only the similarity of name,
and notes that the discussion of categories and categorization in computer science, does not always have the emphasis it receives in information science in studies on knowledge
representation. The approach of Deleuze and Guattari's rhizome, was treated as instigator of reflections on the validity of the hierarchical tree model structure and the possibilities of its expansion. It concludes that the construction of ontologies can not ignore the terminological
and conceptual analysis, as it's understood by the terminology and by the information
science accumulated in the theoretical and methodological basis for the construction of
indexing languages and, on the other hand, the construction of flexible indexing languages can not ignore the representational model of ontologies which are more capable for formalization and interoperability.
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Arabito, Stefania. « Perceptions of empowerment and the pitfalls of communication : an exploratory case study at the University of Trieste Library System ». Thesis, 2005. http://eprints.rclis.org/11711/1/perceptions_of_empowerment.pdf.
Texte intégralRésumé :
The management of change has become a top priority in academic libraries.
A viable model is the learning organization, as it aims at enhancing the capacity of the staff at all levels for innovation and growth.
This study investigates the relations between empowerment – considered to be the hub of this management practice - and communication – considered to be a strategic imperative in participative organizations.
The research questions were:
How do the Library System staff feel about empowerment?
How do library directors feel about empowerment?
How can communication affect empowerment practices?
Both empowerment and communication are amply described in the literature as being context-bound, multi-faceted and multi-dimensional concepts, which can only be explored in a given environment from a constructivist perspective and with no a priori assumptions.
This is accordingly an exploratory case study, based on a qualitative approach and on intensity sampling. Data were collected through in-depth semi-structured interviews (with library directors), mini focus groups (with the staff), and observations of meetings (of the Library System steering committee).
Cross-analysis showed that there was common ground to build on through adequate negotiation, such as the aspiration for a people-centred organization and the importance of having a project and a vision.
Both empowerment and communication, however, leave room for pitfalls and may create divisiveness if organizational communication is deficient and defective.
Strategic and interpersonal communication turned out to have a fundamental role in building up the trust that makes empowerment practices possible by overcoming “us and them” feelings, local subcultures and defensive behaviours.
The Library System should offer opportunities for meeting and exchanging opinions, sharing the vision, and developing a common sense of belonging and ownership.
Livres sur le sujet "FZ. None of these, but in this section"
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Mathematics of probability. Providence, Rhode Island : American Mathematical Society, 2013.
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1949-, Libgober A. (Anatoly), Cogolludo-Agustín José Ignacio et Hironaka Eriko 1962-, dir. Topology of algebraic varieties and singularities : Conference in honor of Anatoly Libgober's 60th birthday, June 22-26, 2009, Jaca, Huesca, Spain. Providence, R.I : American Mathematical Society, 2011.
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Center for Mathematics at Notre Dame et American Mathematical Society, dir. Toplogy and field theories : Center for Mathematics at Notre Dame, Center for Mathematics at Notre Dame : summer school and conference, Topology and field theories, May 29-June 8, 2012, University of Notre Dame, Notre Dame, Indiana. Providence, Rhode Island : American Mathematical Society, 2014.
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Ahmed, S. E. (Syed Ejaz), 1957- editor of compilation, dir. Perspectives on big data analysis : Methodologies and applications : International Workshop on Perspectives on High-Dimensional Data Anlaysis II, May 30-June 1, 2012, Centre de Recherches Mathématiques, University de Montréal, Montréal, Québec, Canada. Providence, Rhode Island : American Mathematical Society, 2014.
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Riemann surfaces by way of complex analytic geometry. Providence, R.I : American Mathematical Society, 2011.
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Conference Board of the Mathematical Sciences et National Science Foundation (U.S.), dir. Lectures on the energy critical nonlinear wave equation. Providence, Rhode Island : Published for the Conference Board of the Mathematical Sciences by the American Mathematical Society, with support from the National Science Foundation, 2015.
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The ultimate challenge : The 3x+1 problem. Providence, R.I : American Mathematical Society, 2010.
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From riches to raags : 3-manifolds, right-angled artin groups, and cubical geometry. Providence, Rhode Island : Published for the Conference Board of the Mathematical Sciences by the American Mathematical Society, Providence, Rhode Island with support from the National Science Foundation, 2012.
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Morse, Robert Fitzgerald, editor of compilation, Nikolova-Popova, Daniela, 1952- editor of compilation et Witherspoon, Sarah J., 1966- editor of compilation, dir. Group theory, combinatorics and computing : International Conference in honor of Daniela Nikolova-Popova's 60th birthday on Group Theory, Combinatorics and Computing, October 3-8, 2012, Florida Atlantic University, Boca Raton, Florida. Providence, Rhode Island : American Mathematical Society, 2013.
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Flannery, D. L. (Dane Laurence), 1965-, dir. Algebraic design theory. Providence, R.I : American Mathematical Society, 2011.
Trouver le texte intégralChapitres de livres sur le sujet "FZ. None of these, but in this section"
1
Smithies, Declan. « Luminosity ». Dans The Epistemic Role of Consciousness, 345–79. Oxford University Press, 2019. http://dx.doi.org/10.1093/oso/9780199917662.003.0011.
Texte intégralRésumé :
Chapter 11 defends the thesis that some phenomenal and epistemic conditions are luminous in the sense that you’re always in a position to know whether or not they obtain. Section 11.1 draws a distinction between epistemic and doxastic senses of luminosity and argues that some conditions are epistemically luminous even if none are doxastically luminous. Section 11.2 uses this distinction in solving Ernest Sosa’s version of the problem of the speckled hen. The same distinction is applied to Timothy Williamson’s anti-luminosity argument in section 11.3, his argument against epistemic iteration principles in section 11.4, and his argument for improbable knowing in section 11.5. Section 11.6 concludes by explaining why this defense of luminosity is not merely a pointless compromise.
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« Literary Selections ». Dans Roots of the Black Chicago Renaissance, sous la direction de Richard A. Courage et Christopher Robert Reed, 245. University of Illinois Press, 2020. http://dx.doi.org/10.5622/illinois/9780252043055.003.0013.
Texte intégralRésumé :
Editors’ Note: Our study concludes with a section comprising three literary selections that we intend to break new ground for a scholarly collection. None of the selections is a conventional academic essay, each belongs to a different genre of writing, and each amplifies the light already shone on the roots of the Black Chicago Renaissance....
3
Phillips, David. « The Critique of Common-Sense Morality (Methods III.I–III.XI) ». Dans Sidgwick's The Methods of Ethics, 96–119. Oxford University Press, 2022. http://dx.doi.org/10.1093/oso/9780197539613.003.0006.
Texte intégralRésumé :
This chapter focuses on The Methods of Ethics, Book III, Chapters I through XI. Its topic is Sidgwick’s critique of the theory he calls “common-sense morality” or “dogmatic intuitionism.” The first section introduces this theory, noting problems with both Sidgwick’s names for it. The second section discusses the project of Chapters I through XI, making the principles of common-sense morality clear and precise. The third section introduces the four conditions Sidgwick uses to test putative axioms. The fourth section outlines his argument that none of the principles of common-sense morality satisfy the four conditions, focusing on the example of promissory obligation. The fifth section considers two responses: defending absolutist deontology, and moving to moderate deontology by introducing, as W. D. Ross does, the concept of prima facie duty. The final section raises questions about the fairness of Sidgwick’s critique.
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Collins, Richard B., Dale A. Oesterle et Lawrence Friedman. « Schedule ». Dans The Colorado State Constitution, 457–62. Oxford University Press, 2020. http://dx.doi.org/10.1093/oso/9780190907723.003.0030.
Texte intégralRésumé :
This chapter discusses the “Schedule” of the Colorado Constitution. Transition to statehood required that territorial institutions and law be retained until expressly replaced. At the end of the original constitution, twenty-two sections under the heading of Schedule detailed how the transition should work. Although almost entirely obsolete, none has been repealed. Schedule Section 1 was invoked by enterprising defense lawyers in efforts to get their clients off on a technicality. At least one succeeded. Section 20, requiring that presidential electors “be chosen by direct vote of the people,” could be read as obsolete or as a continuing constitutional rule. It is the only section with possible relevance to a current dispute.
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Knee, Jonathan A. « Lessons from Clown School ». Dans Class Clowns, 202–32. Columbia University Press, 2016. http://dx.doi.org/10.7312/columbia/9780231179287.003.0007.
Texte intégralRésumé :
The final section of Class Clowns tries to draw some conclusions from the analyses and case studies. Ten lessons are drawn that should provide guardrails to anyone seeking to play in the education domain. Broadly, the failures highlighted fall into three broad buckets: misguided ambition, misunderstood markets and faulty execution. None of these phenomena are unique to education, but their application takes on a very particular shape in the educational context.
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Anne Franks, Mary. « “Not Where Bodies Live” ». Dans Free Speech in the Digital Age, 137–49. Oxford University Press, 2019. http://dx.doi.org/10.1093/oso/9780190883591.003.0009.
Texte intégralRésumé :
John Perry Barlow, one of the founders of the Electronic Frontier Foundation (EFF), famously claimed in 1996 that the internet “is a world that is both everywhere and nowhere, but it is not where bodies live.” The conception of cyberspace as a realm of pure expression has encouraged an aggressively anti-regulatory approach to the internet. This approach was essentially codified in U.S. federal law in Section 230 of the Communications Decency Act, which invokes free speech principles to provide broad immunity for online intermediaries against liability for the actions of those who use their services. The free speech frame has encouraged an abstract approach to online conduct that downplays its material conditions and impact. Online intermediaries use Section 230 as both a shield and a sword—simultaneously avoiding liability for the speech of others while benefiting from that speech. In the name of free expression, Section 230 allows powerful internet corporations to profit from harmful online conduct while absorbing none of its costs.
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Schram, Frederick R., et Stefan Koenemann. « Mictacea ». Dans Evolution and Phylogeny of Pancrustacea, 362–69. Oxford University Press, 2021. http://dx.doi.org/10.1093/oso/9780195365764.003.0028.
Texte intégralRésumé :
Mictacea demonstrates the confusion that occurs when animals share so many primitive features. Modest Guţu in fact erected a number of orders to accommodate them, but these do not seem entirely justified. Although the two orders erected by Guţu currently do not have much support, in fairness it must be recognized that molecules, or information from yet-to-be-recognized mictacean taxa, could change the situation. In this case, Guţu’s Bochusacea and Cosinzeneacea might yet prove useful. They inhabit anchialine caves and the deep sea. The animals are small, slender, and subcylindrical in outline. The diagnosis of Guţu to the contrary, none of these animals appear particularly “flattened” in cross-section.
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Sarch, Alexander. « The Scope of the Willful Ignorance Doctrine (I) ». Dans Criminally Ignorant, 85–108. Oxford University Press, 2019. http://dx.doi.org/10.1093/oso/9780190056575.003.0004.
Texte intégralRésumé :
Determining when the equal culpability thesis holds sets the boundaries in which the willful ignorance doctrine is to be applied. Chapter 3 thus considers the best existing attempts to specify the conditions in which the equal culpability thesis holds, but proceeds to argue that none succeeds. Still, each failure is instructive. First, the chapter argues against the unrestricted equal culpability thesis. Not all willful ignorance, it turns out, is as culpable as the analogous knowing misconduct. Then the chapter argues against the three leading attempts to restrict the thesis. Section II argues against a restriction that appeals to bad motives, while Section III argues against a common counterfactual restriction (according to which willful ignorance is as culpable as knowing misconduct when one would do the actus reus even with knowledge). The latter proposal fails since criminal culpability does not depend on considerations about counterfactual conduct or one’s willingness to misbehave. Finally, Section IV discusses a third restriction, offered by Deborah Hellman, which asks whether the decision to remain in ignorance was itself justified. This version of the thesis is on the right track, but still requires refinement in important ways.
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Fabre, Cécile. « Building Blocks ». Dans Spying Through a Glass Darkly, 12–36. Oxford University Press, 2022. http://dx.doi.org/10.1093/oso/9780198833765.003.0002.
Texte intégralRésumé :
This chapter sets the stage for the remainder of the book. It provides an overview of the ethics of spying in classical moral and political thought. It examines three possible approaches to espionage: (a) the dirty-hands approach, which sees espionage as a necessary evil; (b) the contractarian view that espionage is best defended by appeal to normative conventions endorsed by all; (c) the view that the most fruitful way to construct an ethics of espionage is through the lens of just-war theory. None of those approaches are fully satisfactory, though they provide building blocks for the approach taken in this book. The final section sets out the normative principles on which the book rests.
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Adams, Robert Merrihew. « God and Possibilities ». Dans What Is, and What Is In Itself, 194–212. Oxford University Press, 2022. http://dx.doi.org/10.1093/oso/9780192856135.003.0012.
Texte intégralRésumé :
Section 11.1 of this chapter discusses how (and whether!) God can know all possibilities without actualizing all of them. For if unactualized conscious states and processes are to be permanent objects of actual thoughts in an eternal mind, how different is that from their being actual conscious states and processes of that mind? It is argued that discursive knowledge of logic and mathematics is not problematic in this way—and in section 11.2 that “intuitive” knowledge of qualities raises additional issues, but none that God could not manage. Section 11.3 points out that God does not need to know nearly as much about possibilities if God need not and does not try to create a “best possible world,” but is motivated by grace and love for actual creatures. Section 11.4 addresses two questions about causal explanation: First, the teleological question: “What am I doing, or at least trying to do, and why am I trying to do it?” I think I often know an at least roughly right answer to that question. The second and much harder question is “Why is it that I can do what I am trying to do, if indeed I can?” Occasionalism implies that it depends on God. That is where this line of explanations stops. No causal explanation of God’s omnipotence is on offer.
Actes de conférences sur le sujet "FZ. None of these, but in this section"
1
Mao, Wengang, Jonas W. Ringsberg et Igor Rychlik. « The Effect of Whipping/Springing on Fatigue Damage and Extreme Response of Ship Structures ». Dans ASME 2010 29th International Conference on Ocean, Offshore and Arctic Engineering. ASMEDC, 2010. http://dx.doi.org/10.1115/omae2010-20124.
Texte intégralRésumé :
Wave-induced vibrations, also known as whipping and springing, are defined as the high frequency response of ship structures. In this paper, the fatigue damage caused by whipping and springing is presented by investigating the amidships section of a 2800 TEU container ship that operates in the North Atlantic Ocean. A simplified fatigue model, originally from the generalized narrow-band approximation for Gaussian load, is employed to include the damage contribution from wave-induced vibrations. In this model, the significant response range hs and the mean stress up-crossing frequency fz are simplified using only the wave-induced loading and encountered wave frequency, respectively. The capacity and accuracy of the model is illustrated by application on the measurements of the 2800 TEU container ship for different voyages during 2008. The whipping-induced contribution to the extreme response is investigated by means of the level crossing approach. It shows that the level crossing model for Gaussian load cannot be used for the prediction of extreme responses, such as the 100-year stress, based on a half-year full-scale measurement. It is found that a more complicated non-Gaussian model is required to consider the contribution from whipping.
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Rezakhaniha, Rana, Edouard Fonck et Nikos Stergiopulos. « Role of Elastin Degradation in Identification of Vascular Strain Energy Functions ». Dans ASME 2009 Summer Bioengineering Conference. American Society of Mechanical Engineers, 2009. http://dx.doi.org/10.1115/sbc2009-204417.
Texte intégralRésumé :
The vessel wall exhibits relatively strong nonlinear properties and undergoes wide range of deformations. These characteristics make the identification of a strain energy function (SEF), the preferred method to describe the complex nonlinear elastic properties of the vascular tissue. None of the currently proposed structural models succeeded in describing accurately and simultaneously both the pressure-radius (Pro) and pressure-longitudinal force (P-Fz) curves. We hypothesized that the shortcomings of current models are partly due to unaccounted anisotropic properties of elastin.
3
Al-Shuwaikhat, Hisham I., Shaker A. Al-Buhassan, Turki F. Al-Saadoun et Saad M. Al-Driweesh. « Optimizing Production Facilities Using None-Radio Active Source MPFM in Ghawar Field in Saudi Aramco ». Dans SPE Saudi Arabia section Young Professionals Technical Symposium. Society of Petroleum Engineers, 2008. http://dx.doi.org/10.2118/117063-ms.
Texte intégral
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Bansal, Iqbal K. « Hydrophobic Silicon-Direct Bonding for Fabrication of RF Microwave Devices ». Dans ASME 2003 International Mechanical Engineering Congress and Exposition. ASMEDC, 2003. http://dx.doi.org/10.1115/imece2003-41161.
Texte intégralRésumé :
Direct wafer bonding (DWB) is an operation of ultra-fine alignment, joining and thermal bonding of two silicon wafers. The first silicon wafer “handle” substrate is a Czochralski (<CZ>) substrate with N+ arsenic dopant with very low bulk resistivity, whereas second wafer “device” is a float-zone (<FZ>) having extremely high resistivity N-phosphorus dopant. Prior to the joining step, silicon wafers are chemically cleaned in order to minimize surface contamination. The wafer surface is “hydrophobic” which is achieved using an insitu oxide etching process. The surface quality is also characterized in terms of sub-micron light point defects (LPD’s) counts and haze concentration using a laser beam scanning system. After chemical clean, none of the LPD’s counts is greater than 1.0 μ size. The joining step is performed in a Class 100 or better environment by employing a commercial joiner. Then, thermal bonding operation is carried out by employing an extended stream oxidation cycle at elevated temperatures. Typical failure modes of DWB are misalignment errors and “voided” or “disbonded” regions. The area of “voided” regions for each bonded pair is determined by employing a scanning acoustic microscope. Detailed product throughtput and yield data are presented in this paper. A spreading resistivity profile (SRP) system is employed for accurate measurement of doping carrier concentration as a function of the depth. The superior uniformity for capacitance-voltage characteristics of a Si-Si bonded wafer versus an inverse epitaxial silicon wafer substrate is shown in terms of the device performance. The applications of silicon-direct wafer bonded substrates provide a quantum jump in the device electrical performance of PIN diodes.
5
Mohammad, Fouad, et Emmanuel Ayorinde. « Simplified Procedure to Estimate the Wind Turbine Blade Aerodynamic Loadings Without Using CFD ». Dans ASME 2013 International Mechanical Engineering Congress and Exposition. American Society of Mechanical Engineers, 2013. http://dx.doi.org/10.1115/imece2013-65427.
Texte intégralRésumé :
The aerodynamic loadings that act on the blade of a horizontal axis wind turbine change as a function of time due to the instantaneous change of the wind speed, the wind direction and the blade position. The new contribution in this study is the introduction of a simplified non CFD based procedure for the calculation of all the aerodynamic loadings acting on a wind turbine blade. The premise of the current simplified model is that (a) the forces can be modeled by a set of point loads rather than distributed pressures, and (b) the magnitudes of these point loads can be estimated using the below load formulas, (c) an interpolation scheme needed to have all computed forces and moments as a function of the blade lengthwise x. Considering a 14m blade length and utilizing a time dependent set of parameters such as angle of attack, material and air density, wind and blade speed, flow angle, yaw, pitch angles, the centrifugal forces (along x-direction of the blade length), the cross-sectional forces (Fy and Fz) and the twisting moment of the blade (about the x-direction) were calculated for each of all the given time steps. After that the authors explain how to interpolate the calculated loadings (forces and twisting moment) and the right formulas to compute the aerodynamic load vector (the right side of the dynamic equations of motion).
6
Sarafan, Sheida, Priti Wanjara, Henri Champliaud, Denis Thibault et Louis Mathieu. « Evaluation of Electron Beam Welded AISI 415 Stainless Steel ». Dans ASME 2014 International Mechanical Engineering Congress and Exposition. American Society of Mechanical Engineers, 2014. http://dx.doi.org/10.1115/imece2014-39317.
Texte intégralRésumé :
Sustainable manufacturing for assembly of turbines used in hydro power generation systems is driving the development of advanced technologies targeted to reduce life-cycle costs whilst assuring high performance over the prolonged product life-span. The turbine runner, a critical component in hydro power generation systems, requires weld assembly between the crown, band and blade sub-components. With due consideration of the thick-gauge sections involved, design and fabrication of a turbine runner that would integrate a high energy density technology for assembly, such as vacuum electron beam welding (EBW), has marked potential to achieve deep penetration with a low heat input, thereby rendering a weldment with narrow heat-affected zones (HAZ) and low distortion. In this study, the weldability of thick-gauge section AISI 415 martensitic stainless steels that are widely utilized in hydro turbine manufacturing was investigated by EBW. Particularly, bead-on-plate (BOP) welding of 88 mm-thick AISI 415 plate was carried out using a 42 kW high vacuum EBW system. The characteristics of the weldments, such as fusion zone (FZ) and HAZ microstructures and hardness were evaluated. The microstructural constituents across the weldment for process conditions that rendered near-complete penetration were studied and related to the microhardness evolution.
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Weaver, Matthew M., Michael G. Dunn et Tab Heffernan. « Experimental Determination of the Influence of Foreign Particle Ingestion on the Behavior of Hot-Section Components Including Lamilloy® ». Dans ASME 1996 International Gas Turbine and Aeroengine Congress and Exhibition. American Society of Mechanical Engineers, 1996. http://dx.doi.org/10.1115/96-gt-337.
Texte intégralRésumé :
The effect of foreign particle ingestion on hot-section components has been investigated with a series of experiments performed using a one-quarter sector F100-PW-100 annular combustor. The combustor was operated so that the engine corrected conditions were duplicated. The experiments were designed to determine the influence of cooling hole size, hole roughness (laser-drilled vs. EDM), combustor exit temperature and dust concentration on the cooling capability of the component in the presence of dust particles. Cylindrical Lamilloy® specimens, film cooled Inconel cylinders, and F100-PW-220 first stage turbine vanes were investigated. The size distribution of the foreign particles injected into the air stream just upstream of the combustor was consistent with distributions measured at the exit of high compressors for large turbofan engines. The foreign material was a soil composition representative of materials found around the world. Pre- and post-test bench flow measurements suggested that none of the test specimen’s cooling passages or holes were clogged by the foreign particles. Foreign particle deposition on the specimens was experienced with approximate values for the minimum combustor exit temperature and minimum specimen wall temperature for deposition measured.
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Urdaneta, Mario, Alfonso Ortega et Russel V. Westphal. « Experiments and Modeling of the Hydraulic Resistance of In-Line Square Pin Fin Heat Sinks With Top By-Pass Flow ». Dans ASME 2003 International Electronic Packaging Technical Conference and Exhibition. ASMEDC, 2003. http://dx.doi.org/10.1115/ipack2003-35268.
Texte intégralRésumé :
Extensive experiments were performed aimed at obtaining physical insight into the behavior of in-line pin fin heat sinks with pins of square cross-section. Detailed pressure measurements were made inside an array of square pins in order to isolate the inlet, developing, fully developed, and exit static pressure distributions as a function of row number. With this as background data, overall pressure drop was measured for a self-consistent set of aluminum heat sinks in side inlet side exit flow, with top clearance only. Pin heights of 12.5 mm, 17.5 mm, and 22.5 mm, pin pitch of 3.4 mm to 6.33 mm, and pin thickness of 1.5 mm, 2 mm and 2.5mm were evaluated. Base dimensions were kept fixed at 25 × 25 mm. In total, 20 aluminum heat sinks were evaluated. A “two-branch by-pass model” was developed, by allowing inviscid acceleration of the flow in the bypass section, and using pressure loss coefficients obtained under no bypass conditions in the heat sink section. The experimental data compared well to the proposed hydraulic models. Measurements in the array of pins showed that full development of the flow occurs after nine rows, thus indicating that none of the heat sinks tested could be characterized as fully-developed.
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Hu, Kenny S. Y., et Tom I.-P. Shih. « Large-Eddy and RANS Simulations of Heat Transfer in a U-Duct With a High-Aspect Ratio Trapezoidal Cross Section ». Dans ASME Turbo Expo 2018 : Turbomachinery Technical Conference and Exposition. American Society of Mechanical Engineers, 2018. http://dx.doi.org/10.1115/gt2018-75535.
Texte intégralRésumé :
Large-eddy and RANS simulations were performed to examine the details of the heat-transfer mechanisms in a U-duct with a high-aspect ratio trapezoidal cross section at a Reynolds number of 20,000. ANSYS-Fluent was used to perform the simulations. For the large-eddy simulations (LES), the WALE subgrid-scale model was employed, and its inflow boundary condition was provided by a concurrent LES of incompressible fully-developed flow in a straight duct with the same cross section and flow conditions as the U-duct. The grid resolution required to obtain meaningful LES solutions were obtained via a grid sensitivity study of incompressible fully-developed turbulent flow in a straight duct of square cross section, where data from direct numerical simulation (DNS) and experiments are available to validate and guide the simulation. In addition, the grid used satisfies Celik’s criterion, and resolves the Kolmogorov’s −5/3 law. Results were also obtained for the U-duct by using RANS, and three widely used turbulence models were examined — realizable k-ε with the two-layer model in the near-wall region, shear-stress transport (SST) model, and stress-omega full Reynolds stress model (RSM). Results obtained from LES showed unsteady flow separation to occur immediately after the turn region, which none of the RANS models could predict. By being able to capture this unsteady flow mechanism, LES was able to predict the measured heat-transfer downstream of the U-duct. The maximum relative error in the predicted local heat-transfer coefficient was less than 10% in the LES results, but up to 80% in the RANS results.
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Carroll, L. Blair, et Moe S. Madi. « Crack Detection Program on the Cromer to Gretna, Manitoba Section of Enbridge Pipelines Inc. Line 3 ». Dans 2000 3rd International Pipeline Conference. American Society of Mechanical Engineers, 2000. http://dx.doi.org/10.1115/ipc2000-186.
Texte intégralRésumé :
Enbridge Pipelines Inc. Line 3 is an 860mm (34 inch), API 5LX Grade X52 pipeline with nominal wall thickness ranging from 7.14 mm to 12.5 mm. The Canadian portion of the Line runs from Edmonton, Alberta to Gretna, Manitoba. It was constructed between 1963 and 1969 in a series of loops designed to increase the capacity of the Enbridge system. Until 1999 the pipeline operated in a looped configuration with neighboring 24 inch and 48 inch pipelines. Line 3 downstream of Kerrobert, Saskatchewan began operating in straight 34 inch configuration in 1999 following completion of the first phase expansion project known as Terrace Expansion Project that connects the (48 inch) loops with a new (36 inch) pipeline. In 1997, the Pipetronix (now PII) Ultrascan CD in-line inspection tool was run for 283 km from Cromer to Gretna, Manitoba, to identify long seam cracking and pipe body stress corrosion cracking. This section of the line is comprised primarily of pipe manufactured with a double submerged arc welded long seam with short sections of pipe having electric resistance welded long seams. There were two primary objectives set forth in this inspection project. The first was to assess the integrity of this section of Line 3 and identify anomalies, which might affect the future operation of the pipeline. The second objective was to evaluate the performance of the Ultrascan CD tool and determine its potential role in the Enbridge integrity program. A series of excavations have been conducted based upon the analysis of this data and none of the indications identified were considered to be an immediate concern to the integrity of the pipeline. Notably, two of the excavations resulted in the detection of the first two “significant” SCC colonies (based upon the CEPA definition of significant) [1] found on the Enbridge system. This paper will focus on the tool performance requirements established by Enbridge prior to the inspection run which include specific defect type and size and defects at a maximum sensitivity of the tool. In addition, the information obtained as a result of the excavation program and onsite inspection and assessments. The information gathered, from this program were useful in better understanding the tool tolerance in detecting such defects and to better differentiate between them.
Rapports d'organisations sur le sujet "FZ. None of these, but in this section"
1
Adams, Sunny, Madison Story et Adam Smith. Evaluation of 11 buildings in the Fort McCoy cantonment. Engineer Research and Development Center (U.S.), septembre 2022. http://dx.doi.org/10.21079/11681/45350.
Texte intégralRésumé :
The United States Congress codified the National Historic Preservation Act of 1966 (NHPA), the nation’s most effective cultural resources legislation to date, mostly through establishing the National Register of Historic Places (NRHP). The NHPA requires federal agencies to address their cultural resources, which are defined as any prehistoric or historic district, site, building, structure, or object. Section 110 of the NHPA requires federal agencies to inventory and evaluate their cultural resources, and Section 106 requires them to determine the effect of federal undertakings on those potentially eligible for the NRHP. Fort McCoy is in west-central Wisconsin, entirely within Monroe County. It was first established as the Sparta Maneuver Tract in 1909. The post was renamed Camp McCoy in 1926. Since 1974, it has been known as Fort McCoy. This report provides historic context and determinations of eligibility for buildings in the cantonment constructed between 1946 and 1975 and concludes that none are eligible for the NRHP. In consultation with the Wisconsin State Historic Preservation Officer (WISHPO), this work fulfills Section 110 requirements for these buildings.
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Price, Roz. Climate Adaptation : Lessons and Insights for Governance, Budgeting, and Accountability. Institute of Development Studies (IDS), décembre 2020. http://dx.doi.org/10.19088/k4d.2022.008.
Texte intégralRésumé :
This rapid review draws on literature from academic, policy and non-governmental organisation sources. There is a huge literature on climate governance issues in general, but less is known about effective support and the political-economy of adaptation. A large literature base and case studies on climate finance accountability and budgeting in governments is nascent and growing. Section 2 of this report briefly discusses governance of climate change issues, with a focus on the complexity and cross-cutting nature of climate change compared to the often static organisational landscape of government structured along sectoral lines. Section 3 explores green public financial management (PFM). Section 4 then brings together several principles and lessons learned on green PFM highlighted in the guidance notes. Transparency and accountability lessons are then highlighted in Section 5. The Key findings are: 1) Engaging with the governance context and the political economy of climate governance and financing is crucial to climate objectives being realised. 2) More attention is needed on whether and how governments are prioritising adaptation and resilience in their own operations. 3) Countries in Africa further along in the green PFM agenda give accounts of reform approaches that are gradual, iterative and context-specific, building on existing PFM systems and their functionality. 4) A well-functioning “accountability ecosystem” is needed in which state and non-state accountability actors engage with one another. 5) Climate change finance accountability systems and ecosystems in countries are at best emerging. 6) Although case studies from Nepal, the Philippines and Bangladesh are commonly cited in the literature and are seen as some of the most advanced developing country examples of green PFM, none of the countries have had significant examples of collaboration and engagement between actors. 7) Lessons and guiding principles for green PFM reform include: use the existing budget cycle and legal frameworks; ensure that the basic elements of a functional PFM system are in place; strong leadership of the Ministry of Finance (MoF) and clear linkages with the overall PFM reform agenda are needed; smart sequencing of reforms; real political ownership and clearly defined roles and responsibilities; and good communication to stakeholders).
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Goeckeritz, Joel, Nathan Schank, Ryan L Wood, Beverly L Roeder et Alonzo D Cook. Use of Urinary Bladder Matrix Conduits in a Rat Model of Sciatic Nerve Regeneration after Nerve Transection Injury. Science Repository, décembre 2022. http://dx.doi.org/10.31487/j.rgm.2022.03.01.
Texte intégralRésumé :
Previous research has demonstrated the use of single-channel porcine-derived urinary bladder matrix (UBM) conduits in segmental-loss, peripheral nerve repairs as comparable to criterion-standard nerve autografts. This study aimed to replicate and expand upon this research with additional novel UBM conduits and coupled therapies. Fifty-four Wistar Albino rats were divided into 6 groups, and each underwent a surgical neurectomy to remove a 7-millimeter section of the sciatic nerve. Bridging of this nerve gap and treatment for each group was as follows: i) reverse autograft—the segmented nerve was reversed 180 degrees and used to reconnect the proximal and distal nerve stumps; ii) the nerve gap was bridged via a silicone conduit; iii) a single-channel UBM conduit; iv) a multi-channel UBM conduit; v) a single-channel UBM conduit identical to group 3 coupled with fortnightly transcutaneous electrical nerve stimulation (TENS); vi) or, a multi-channel UBM conduit identical to group 4 coupled with fortnightly TENS. The extent of nerve recovery was assessed by behavioural parameters: foot fault asymmetry scoring measured weekly for six weeks; electrophysiological parameters: compound muscle action potential (CMAP) amplitudes, measured at weeks 0 and 6; and morphological parameters: total fascicle areas, myelinated fiber counts, fiber densities, and fiber sizes measured at week 6. All the above parameters demonstrated recovery of the test groups (3-6) as being either comparable or less than that of reverse autograft, but none were shown to outperform reverse autograft. As such, UBM conduits may yet prove to be an effective treatment to repair relatively short segmental peripheral nerve injuries, but further research is required to demonstrate greater efficacy over nerve autografts.
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Goeckeritz, Joel, Nathan Schank, Ryan L Wood, Beverly L Roeder et Alonzo D Cook. Use of Urinary Bladder Matrix Conduits in a Rat Model of Sciatic Nerve Regeneration after Nerve Transection Injury. Science Repository, décembre 2022. http://dx.doi.org/10.31487/j.rgm.2022.03.01.sup.
Texte intégralRésumé :
Previous research has demonstrated the use of single-channel porcine-derived urinary bladder matrix (UBM) conduits in segmental-loss, peripheral nerve repairs as comparable to criterion-standard nerve autografts. This study aimed to replicate and expand upon this research with additional novel UBM conduits and coupled therapies. Fifty-four Wistar Albino rats were divided into 6 groups, and each underwent a surgical neurectomy to remove a 7-millimeter section of the sciatic nerve. Bridging of this nerve gap and treatment for each group was as follows: i) reverse autograft—the segmented nerve was reversed 180 degrees and used to reconnect the proximal and distal nerve stumps; ii) the nerve gap was bridged via a silicone conduit; iii) a single-channel UBM conduit; iv) a multi-channel UBM conduit; v) a single-channel UBM conduit identical to group 3 coupled with fortnightly transcutaneous electrical nerve stimulation (TENS); vi) or, a multi-channel UBM conduit identical to group 4 coupled with fortnightly TENS. The extent of nerve recovery was assessed by behavioural parameters: foot fault asymmetry scoring measured weekly for six weeks; electrophysiological parameters: compound muscle action potential (CMAP) amplitudes, measured at weeks 0 and 6; and morphological parameters: total fascicle areas, myelinated fiber counts, fiber densities, and fiber sizes measured at week 6. All the above parameters demonstrated recovery of the test groups (3-6) as being either comparable or less than that of reverse autograft, but none were shown to outperform reverse autograft. As such, UBM conduits may yet prove to be an effective treatment to repair relatively short segmental peripheral nerve injuries, but further research is required to demonstrate greater efficacy over nerve autografts.
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Friedler, Haley S., Michelle B. Leavy, Eric Bickelman, Barbara Casanova, Diana Clarke, Danielle Cooke, Andy DeMayo et al. Outcome Measure Harmonization and Data Infrastructure for Patient-Centered Outcomes Research in Depression : Data Use and Governance Toolkit. Agency for Healthcare Research and Quality (AHRQ), octobre 2021. http://dx.doi.org/10.23970/ahrqepcwhitepaperdepressiontoolkit.
Texte intégralRésumé :
Executive Summary Patient registries are important tools for advancing research, improving healthcare quality, and supporting health policy. Registries contain vast amounts of data that could be used for new purposes when linked with other sources or shared with researchers. This toolkit was developed to summarize current best practices and provide information to assist registries interested in sharing data. The contents of this toolkit were developed based on review of the literature, existing registry practices, interviews with registries, and input from key stakeholders involved in the sharing of registry data. While some information in this toolkit may be relevant in other countries, this toolkit focuses on best practices for sharing data within the United States. Considerations related to data sharing differ across registries depending on the type of registry, registry purpose, funding source(s), and other factors; as such, this toolkit describes general best practices and considerations rather than providing specific recommendations. Finally, data sharing raises complex legal, regulatory, operational, and technical questions, and none of the information contained herein should be substituted for legal advice. The toolkit is organized into three sections: “Preparing to Share Data,” “Governance,” and “Procedures for Reviewing and Responding to Data Requests.” The section on “Preparing to Share Data” discusses the role of appropriate legal rights to further share the data and the need to follow all applicable ethical regulations. Registries should also prepare for data sharing activities by ensuring data are maintained appropriately and developing policies and procedures for governance and data sharing. The “Governance” section describes the role of governance in data sharing and outlines key governance tasks, including defining and staffing relevant oversight bodies; developing a data request process; reviewing data requests; and overseeing access to data by the requesting party. Governance structures vary based on the scope of data shared and registry resources. Lastly, the section on “Procedures for Reviewing and Responding to Data Requests” discusses the operational steps involved in sharing data. Policies and procedures for sharing data may depend on what types of data are available for sharing and with whom the data can be shared. Many registries develop a data request form for external researchers interested in using registry data. When reviewing requests, registries may consider whether the request aligns with the registry’s mission/purpose, the feasibility and merit of the proposed research, the qualifications of the requestor, and the necessary ethical and regulatory approvals, as well as administrative factors such as costs and timelines. Registries may require researchers to sign a data use agreement or other such contract to clearly define the terms and conditions of data use before providing access to the data in a secure manner. The toolkit concludes with a list of resources and appendices with supporting materials that registries may find helpful.
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Friedler, Haley S., Michelle B. Leavy, Eric Bickelman, Barbara Casanova, Diana Clarke, Danielle Cooke, Andy DeMayo et al. Outcome Measure Harmonization and Data Infrastructure for Patient-Centered Outcomes Research in Depression : Data Use and Governance Toolkit. Agency for Healthcare Research and Quality (AHRQ), octobre 2021. http://dx.doi.org/10.23970/ahrqepcwhitepaperdepressiontoolkit.
Texte intégralRésumé :
Executive Summary Patient registries are important tools for advancing research, improving healthcare quality, and supporting health policy. Registries contain vast amounts of data that could be used for new purposes when linked with other sources or shared with researchers. This toolkit was developed to summarize current best practices and provide information to assist registries interested in sharing data. The contents of this toolkit were developed based on review of the literature, existing registry practices, interviews with registries, and input from key stakeholders involved in the sharing of registry data. While some information in this toolkit may be relevant in other countries, this toolkit focuses on best practices for sharing data within the United States. Considerations related to data sharing differ across registries depending on the type of registry, registry purpose, funding source(s), and other factors; as such, this toolkit describes general best practices and considerations rather than providing specific recommendations. Finally, data sharing raises complex legal, regulatory, operational, and technical questions, and none of the information contained herein should be substituted for legal advice. The toolkit is organized into three sections: “Preparing to Share Data,” “Governance,” and “Procedures for Reviewing and Responding to Data Requests.” The section on “Preparing to Share Data” discusses the role of appropriate legal rights to further share the data and the need to follow all applicable ethical regulations. Registries should also prepare for data sharing activities by ensuring data are maintained appropriately and developing policies and procedures for governance and data sharing. The “Governance” section describes the role of governance in data sharing and outlines key governance tasks, including defining and staffing relevant oversight bodies; developing a data request process; reviewing data requests; and overseeing access to data by the requesting party. Governance structures vary based on the scope of data shared and registry resources. Lastly, the section on “Procedures for Reviewing and Responding to Data Requests” discusses the operational steps involved in sharing data. Policies and procedures for sharing data may depend on what types of data are available for sharing and with whom the data can be shared. Many registries develop a data request form for external researchers interested in using registry data. When reviewing requests, registries may consider whether the request aligns with the registry’s mission/purpose, the feasibility and merit of the proposed research, the qualifications of the requestor, and the necessary ethical and regulatory approvals, as well as administrative factors such as costs and timelines. Registries may require researchers to sign a data use agreement or other such contract to clearly define the terms and conditions of data use before providing access to the data in a secure manner. The toolkit concludes with a list of resources and appendices with supporting materials that registries may find helpful.
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Stavland, Arne, Siv Marie Åsen, Arild Lohne, Olav Aursjø et Aksel Hiorth. Recommended polymer workflow : Lab (cm and m scale). University of Stavanger, novembre 2021. http://dx.doi.org/10.31265/usps.201.
Texte intégralRésumé :
Polymer flooding is one of the most promising EOR methods (Smalley et al. 2018). It is well known and has been used successfully (Pye 1964; Standnes & Skjevrak 2014; Sheng et al. 2015). From a technical perspective we recommend that polymer flooding should be considered as a viable EOR method on the Norwegian Continental Shelf for the following reasons: 1. More oil can be produced with less water injected; this is particularly important for the NCS which are currently producing more water than oil 2. Polymers will increase the aerial sweep and improve the ultimate recovery, provided a proper injection strategy 3. Many polymer systems are available, and it should be possible to tailor their chemical composition to a wide range of reservoir conditions (temperature and salinity) 4. Polymer systems can be used to block water from short circuiting injection production wells 5. Polymer combined with low salinity injection water has many benefits: a lower polymer concentration can be used to reach target viscosity, less mechanical degradation, less adsorption, and a potential reduction in Sor due to a low salinity wettability effect. There are some hurdles when considering polymer flooding that needs to be considered: 1. Many polymer systems are not at the present considered as green chemicals; thus, reinjection of produced water is needed. However, results from polymer degradation studies in the IORCentre indicates that a. High molecular weight polymers are quickly degraded to low molecular weight. In case of accidental release to the ocean low molecular weight polymers are diluted and the lifetime of the spill might be quite short. According to Caulfield et al. (2002) HPAM is not toxic, and will not degrade to the more environmentally problematic acrylamide. b. In the DF report for environmental impact there are case studies using the DREAM model to predict the transport of chemical spills. This model is coupled with polymer (sun exposure) degradation data from the IORCentre to quantify the lifetime of polymer spills. This approach should be used for specific field cases to quantify the environmental risk factor. 2. Care must be taken to prepare the polymer solution offshore. Chokes and vales might be a challenge but can be mitigating according to the results from the large-scale testing done in the IORCentre (Stavland et al. 2021). None of the above-mentioned challenges are server enough to not consider polymer flooding. HPAM is neither toxic, nor bio-accumulable, or bio-persistent and the CO2 footprint from a polymer flood may be significantly less than a water flood (Dupuis et al. 2021). There are at least two contributing factors to this statement, which we will return in detail to in the next section i) during linear displacement polymer injection will produce more oil for the same amount of water injected, hence the lifetime of the field can be shortened ii) polymers increase the arial sweep reducing the need for wells.
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Mazzoni, Silvia, Nicholas Gregor, Linda Al Atik, Yousef Bozorgnia, David Welch et Gregory Deierlein. Probabilistic Seismic Hazard Analysis and Selecting and Scaling of Ground-Motion Records (PEER-CEA Project). Pacific Earthquake Engineering Research Center, University of California, Berkeley, CA, novembre 2020. http://dx.doi.org/10.55461/zjdn7385.
Texte intégralRésumé :
This report is one of a series of reports documenting the methods and findings of a multi-year, multi-disciplinary project coordinated by the Pacific Earthquake Engineering Research Center (PEER) and funded by the California Earthquake Authority (CEA). The overall project is titled “Quantifying the Performance of Retrofit of Cripple Walls and Sill Anchorage in Single-Family Wood-Frame Buildings,” henceforth referred to as the “PEER–CEA Project.” The overall objective of the PEER–CEA Project is to provide scientifically based information (e.g., testing, analysis, and resulting loss models) that measure and assess the effectiveness of seismic retrofit to reduce the risk of damage and associated losses (repair costs) of wood-frame houses with cripple wall and sill anchorage deficiencies as well as retrofitted conditions that address those deficiencies. Tasks that support and inform the loss-modeling effort are: (1) collecting and summarizing existing information and results of previous research on the performance of wood-frame houses; (2) identifying construction features to characterize alternative variants of wood-frame houses; (3) characterizing earthquake hazard and ground motions at representative sites in California; (4) developing cyclic loading protocols and conducting laboratory tests of cripple wall panels, wood-frame wall subassemblies, and sill anchorages to measure and document their response (strength and stiffness) under cyclic loading; and (5) the computer modeling, simulations, and the development of loss models as informed by a workshop with claims adjustors. This report is a product of Working Group 3 (WG3), Task 3.1: Selecting and Scaling Ground-motion records. The objective of Task 3.1 is to provide suites of ground motions to be used by other working groups (WGs), especially Working Group 5: Analytical Modeling (WG5) for Simulation Studies. The ground motions used in the numerical simulations are intended to represent seismic hazard at the building site. The seismic hazard is dependent on the location of the site relative to seismic sources, the characteristics of the seismic sources in the region and the local soil conditions at the site. To achieve a proper representation of hazard across the State of California, ten sites were selected, and a site-specific probabilistic seismic hazard analysis (PSHA) was performed at each of these sites for both a soft soil (Vs30 = 270 m/sec) and a stiff soil (Vs30=760 m/sec). The PSHA used the UCERF3 seismic source model, which represents the latest seismic source model adopted by the USGS [2013] and NGA-West2 ground-motion models. The PSHA was carried out for structural periods ranging from 0.01 to 10 sec. At each site and soil class, the results from the PSHA—hazard curves, hazard deaggregation, and uniform-hazard spectra (UHS)—were extracted for a series of ten return periods, prescribed by WG5 and WG6, ranging from 15.5–2500 years. For each case (site, soil class, and return period), the UHS was used as the target spectrum for selection and modification of a suite of ground motions. Additionally, another set of target spectra based on “Conditional Spectra” (CS), which are more realistic than UHS, was developed [Baker and Lee 2018]. The Conditional Spectra are defined by the median (Conditional Mean Spectrum) and a period-dependent variance. A suite of at least 40 record pairs (horizontal) were selected and modified for each return period and target-spectrum type. Thus, for each ground-motion suite, 40 or more record pairs were selected using the deaggregation of the hazard, resulting in more than 200 record pairs per target-spectrum type at each site. The suites contained more than 40 records in case some were rejected by the modelers due to secondary characteristics; however, none were rejected, and the complete set was used. For the case of UHS as the target spectrum, the selected motions were modified (scaled) such that the average of the median spectrum (RotD50) [Boore 2010] of the ground-motion pairs follow the target spectrum closely within the period range of interest to the analysts. In communications with WG5 researchers, for ground-motion (time histories, or time series) selection and modification, a period range between 0.01–2.0 sec was selected for this specific application for the project. The duration metrics and pulse characteristics of the records were also used in the final selection of ground motions. The damping ratio for the PSHA and ground-motion target spectra was set to 5%, which is standard practice in engineering applications. For the cases where the CS was used as the target spectrum, the ground-motion suites were selected and scaled using a modified version of the conditional spectrum ground-motion selection tool (CS-GMS tool) developed by Baker and Lee [2018]. This tool selects and scales a suite of ground motions to meet both the median and the user-defined variability. This variability is defined by the relationship developed by Baker and Jayaram [2008]. The computation of CS requires a structural period for the conditional model. In collaboration with WG5 researchers, a conditioning period of 0.25 sec was selected as a representative of the fundamental mode of vibration of the buildings of interest in this study. Working Group 5 carried out a sensitivity analysis of using other conditioning periods, and the results and discussion of selection of conditioning period are reported in Section 4 of the WG5 PEER report entitled Technical Background Report for Structural Analysis and Performance Assessment. The WG3.1 report presents a summary of the selected sites, the seismic-source characterization model, and the ground-motion characterization model used in the PSHA, followed by selection and modification of suites of ground motions. The Record Sequence Number (RSN) and the associated scale factors are tabulated in the Appendices of this report, and the actual time-series files can be downloaded from the PEER Ground-motion database Portal (https://ngawest2.berkeley.edu/)(link is external).
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Jorgensen, Frieda, Andre Charlett, Craig Swift, Anais Painset et Nicolae Corcionivoschi. A survey of the levels of Campylobacter spp. contamination and prevalence of selected antimicrobial resistance determinants in fresh whole UK-produced chilled chickens at retail sale (non-major retailers). Food Standards Agency, juin 2021. http://dx.doi.org/10.46756/sci.fsa.xls618.
Texte intégralRésumé :
Campylobacter spp. are the most common bacterial cause of foodborne illness in the UK, with chicken considered to be the most important vehicle for this organism. The UK Food Standards Agency (FSA) agreed with industry to reduce Campylobacter spp. contamination in raw chicken and issued a target to reduce the prevalence of the most contaminated chickens (those with more than 1000 cfu per g chicken neck skin) to below 10 % at the end of the slaughter process, initially by 2016. To help monitor progress, a series of UK-wide surveys were undertaken to determine the levels of Campylobacter spp. on whole UK-produced, fresh chicken at retail sale in the UK. The data obtained for the first four years was reported in FSA projects FS241044 (2014/15) and FS102121 (2015 to 2018). The FSA has indicated that the retail proxy target for the percentage of highly contaminated raw whole retail chickens should be less than 7% and while continued monitoring has demonstrated a sustained decline for chickens from major retailer stores, chicken on sale in other stores have yet to meet this target. This report presents results from testing chickens from non-major retailer stores (only) in a fifth survey year from 2018 to 2019. In line with previous practise, samples were collected from stores distributed throughout the UK (in proportion to the population size of each country). Testing was performed by two laboratories - a Public Health England (PHE) laboratory or the Agri-Food & Biosciences Institute (AFBI), Belfast. Enumeration of Campylobacter spp. was performed using the ISO 10272-2 standard enumeration method applied with a detection limit of 10 colony forming units (cfu) per gram (g) of neck skin. Antimicrobial resistance (AMR) to selected antimicrobials in accordance with those advised in the EU harmonised monitoring protocol was predicted from genome sequence data in Campylobacter jejuni and Campylobacter coli isolates The percentage (10.8%) of fresh, whole chicken at retail sale in stores of smaller chains (for example, Iceland, McColl’s, Budgens, Nisa, Costcutter, One Stop), independents and butchers (collectively referred to as non-major retailer stores in this report) in the UK that are highly contaminated (at more than 1000 cfu per g) with Campylobacter spp. has decreased since the previous survey year but is still higher than that found in samples from major retailers. 8 whole fresh raw chickens from non-major retailer stores were collected from August 2018 to July 2019 (n = 1009). Campylobacter spp. were detected in 55.8% of the chicken skin samples obtained from non-major retailer shops, and 10.8% of the samples had counts above 1000 cfu per g chicken skin. Comparison among production plant approval codes showed significant differences of the percentages of chicken samples with more than 1000 cfu per g, ranging from 0% to 28.1%. The percentage of samples with more than 1000 cfu of Campylobacter spp. per g was significantly higher in the period May, June and July than in the period November to April. The percentage of highly contaminated samples was significantly higher for samples taken from larger compared to smaller chickens. There was no statistical difference in the percentage of highly contaminated samples between those obtained from chicken reared with access to range (for example, free-range and organic birds) and those reared under standard regime (for example, no access to range) but the small sample size for organic and to a lesser extent free-range chickens, may have limited the ability to detect important differences should they exist. Campylobacter species was determined for isolates from 93.4% of the positive samples. C. jejuni was isolated from the majority (72.6%) of samples while C. coli was identified in 22.1% of samples. A combination of both species was found in 5.3% of samples. C. coli was more frequently isolated from samples obtained from chicken reared with access to range in comparison to those reared as standard birds. C. jejuni was less prevalent during the summer months of June, July and August compared to the remaining months of the year. Resistance to ciprofloxacin (fluoroquinolone), erythromycin (macrolide), tetracycline, (tetracyclines), gentamicin and streptomycin (aminoglycosides) was predicted from WGS data by the detection of known antimicrobial resistance determinants. Resistance to ciprofloxacin was detected in 185 (51.7%) isolates of C. jejuni and 49 (42.1%) isolates of C. coli; while 220 (61.1%) isolates of C. jejuni and 73 (62.9%) isolates of C. coli isolates were resistant to tetracycline. Three C. coli (2.6%) but none of the C. jejuni isolates harboured 23S mutations predicting reduced susceptibility to erythromycin. Multidrug resistance (MDR), defined as harbouring genetic determinants for resistance to at least three unrelated antimicrobial classes, was found in 10 (8.6%) C. coli isolates but not in any C. jejuni isolates. Co-resistance to ciprofloxacin and erythromycin was predicted in 1.7% of C. coli isolates. 9 Overall, the percentages of isolates with genetic AMR determinants found in this study were similar to those reported in the previous survey year (August 2016 to July 2017) where testing was based on phenotypic break-point testing. Multi-drug resistance was similar to that found in the previous survey years. It is recommended that trends in AMR in Campylobacter spp. isolates from retail chickens continue to be monitored to realise any increasing resistance of concern, particulary to erythromycin (macrolide). Considering that the percentage of fresh, whole chicken from non-major retailer stores in the UK that are highly contaminated (at more than 1000 cfu per g) with Campylobacter spp. continues to be above that in samples from major retailers more action including consideration of interventions such as improved biosecurity and slaughterhouse measures is needed to achieve better control of Campylobacter spp. for this section of the industry. The FSA has indicated that the retail proxy target for the percentage of highly contaminated retail chickens should be less than 7% and while continued monitoring has demonstrated a sustained decline for chickens from major retailer stores, chicken on sale in other stores have yet to meet this target.