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1
Chen, Yiping. « Word recognition and reading in Chinese ». Thesis, University of Oxford, 1993. http://ora.ox.ac.uk/objects/uuid:8f034ff4-f07c-459b-95f7-4b0a72e07c45.
Texte intégralRésumé :
Finally, the present thesis develops an analytic account of word recognition and reading in Chinese. Implications are drawn for both experimental studies of normal reading and neuropsychological studies of dyslexia in Chinese.
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Meredew, Victoria. « Perceived control and school attendance ». Thesis, University of Manchester, 2011. https://www.research.manchester.ac.uk/portal/en/theses/perceived-control-and-school-attendance(1d33d2ef-f07c-45d6-af17-3d30acfa7fba).html.
Texte intégralRésumé :
This research explores the link between pupils’ perceived control and their level of attendance in school. Whilst there is research into the link between perceived control and disaffection in pupils it has not been possible to identify any research which links school non-attendance to perceived control. Research into pupils’ reasons for non-attendance identified a range of different factors, many of which the author felt could be attributed to perceived control. Forty-one participants took part in the study. Participants were male and female year nine pupils at two secondary schools in the north west of England. Participants were grouped according to their levels of attendance as high (98%+) attenders, mid-range attenders (90-94%) and low (below 80%) levels of attendance. Participants’ levels of perceived control were measured using the Multi-dimensional Measure of Children’s Perceptions of Control (MMCPC) (Connell 1985). This research also explored the pupils’ experiences of school using appreciative inquiry. Responses on the MMCPC were analysed using a one way ANOVA and descriptive statistics. No significant differences were found between scores for each of the attendance groups and the reasons for this are discussed. Thematic analysis of focus groups with an appreciative inquiry structure identified key themes raised by pupils in regard to positive experiences in school. The findings for both parts of the research are discussed and suggestions for the implications for future research and the practice of teachers and educational psychologists supporting attendance in school are made.
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Khotavivattana, Tanatorn. « ¹⁸F-labelling of new chemotypes for drug discovery ». Thesis, University of Oxford, 2016. https://ora.ox.ac.uk/objects/uuid:d4e8c8fd-f07d-44c3-b95b-5e7ad4127dde.
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In this thesis, the 18F-labelling of new "chemotypes" will be described with the aim of application in pharmaceutically interesting targets. In Chapter 1, a general introduction to the effect of fluorine substituents on molecular properties and reactivity is provided. This includes the application of organofluorine in both medicinal chemistry and positron emission tomography. Chapter 2 describes a novel silver-mediated 18F-labelling of Ar-SCF3, Ar OCF3 and Ar-OCF2H, including [18F]Riluzole, the 18F labelled version of a drug for treatment of amyotrophic lateral sclerosis (ALS). This work demonstrates that AgOTf can induce halogen exchange nucleophilic 18F-fluorination under mild reaction conditions with a wide range of substrates. In addition, the 18F-labelled Ar-SCF3 substrate is further transformed into the [18F]Umemoto reagent in a single step. The Umemoto reagent has been extensively used for electrophilic trifluoromethylation of various functional groups. Therefore the labelling of this reagent could potentially expand the radiochemical space available for PET applications. To augment the utility of this reagent, we developed a late-stage stereoselective trifluoromethylation-thiocyclisation of alkenes using electrophilic trifluoromethylating reagents such as Umemoto reagent or Togni reagent, which will be discussed in Chapter 3. In this process, thiourea acts as both S-nucleophile and CF3 radical initiator; therefore no metal or photoredox catalyst is required. The reaction affords novel trifluoromethylated 2-amino-thiazolines and 2-amino-thiazines, important scaffolds in the development of aspartate beta-secretase enzyme (BACE-1) inhibitors, a therapeutic target for Alzheimer's disease. Chapter 4 investigates the 18F-labelling of a,a-difluoro-a-aryloxyacetic acid, a class of substrate that can serve as a versatile intermediate which can undergo various decarboxylative functionalisation reactions to afford a wide range of novel 18F labelled a fluorinated aryl ethers. Finally, Chapter 5 gives full experimental procedures and characterisation data for all compounds.
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Davies, Elwyn. « Incentives, reputation and learning ». Thesis, University of Oxford, 2016. https://ora.ox.ac.uk/objects/uuid:e5a17fea-f0ac-43dc-977b-acda2e40c8e6.
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Many economic interactions are characterized by imperfect information and imperfect enforcement. This thesis analyzes the use and the effectiveness of incentives, reputation and learning and how economic agents use them to mitigate the problems caused by both. Chapter 1 presents experimental evidence on the use of price incentives and reputational incentives from gift-exchange game lab experiments in Ghana and the United Kingdom. While in the United Kingdom, like in other experiments, participants assigned the role of employers reward high effort by increasing wages and punish low effort by decreasing wages, it appears that Ghanaian participants refrain from doing so. This results in lower average effort in Ghana compared to the United Kingdom. Introducing competition for workers or a reputation mechanism does not improve effort. Chapter 2 further examines low worker productivity in Ghana by empirically testing two other incentive mechanisms: the employer giving feedback and the worker making a pledge in advance. While these incentives on average do not affect effort, they do increase conditional reciprocity of the worker's behalf. Workers receiving a high wage are more likely to exert high effort when feedback and promises are possible. Chapter 3 presents a partial-equilibrium model showing how business networks can lead to higher quality firms overall. The presence of such networks leads to a filtering effect, which means that fewer low-quality firms produce, but also to a lock-out effect, implying that networks redistribute demand to their own members and make production outside the network less viable. Chapter 4 presents a model and experimental evidence on learning and strategic experimentation in the context of a repeated ultimatum game. The model predicts that Proposers make low offers in early periods, hoping that learning will benefit them in later periods. However, when Responders also have strategic considerations, the Responders will strategically reject low offers, which will optimally lead to higher offers. A series of online experiments finds evidence that Responders reject low offers, but cannot disentangle this from distributional preferences and reciprocity concerns.
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Choi, Narae. « Impacts of development-induced displacement on urban locality and settlers : a case-study of the railway upgrading project in Metro Manila ». Thesis, University of Oxford, 2013. http://ora.ox.ac.uk/objects/uuid:cc010100-f0cc-42ae-b48d-a1577d5d8c33.
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Population displacement has long been a controversial companion of development. The central tension has been between the position challenging the kind of development that removes people from their homes, livelihoods and communities, and a managerial position that the impoverishment risks of displacement can be mitigated through an effective intervention. Whereas recent research has been devoted to unpacking a rather unsuccessful performance of involuntary resettlement as a mitigation measure, this study aims to question the assumption of mitigation itself by expanding the concept of development impacts beyond the realm of displacement. Through an empirical study of a railway project in Metro Manila, the Philippines, I examine how urban residents are affected by a large-scale demolition and displacement that took place in their locality. Semi-structured interviews were conducted along the railway tracks after the land was cleared of informal settlements since the study placed particular focus on residents who were not physically displaced. They are identified in my research as non-displaced people. Few studies have addressed the possibility that other people might have been adversely affected in situ and this is particularly so in urban areas. Empirical findings reveal that the physical environment and socio-economic relationships in the locality were significantly transformed through the clearance; impacting the tenure status, livelihoods and social milieu of non-displaced people. Tenure security was important for avoiding displacement but was not a definitive factor as a number of people are still informal settlers who continue to be faced with other eviction threats. For the non-displaced, the physical change of the locality became relevant when their productive capital, notably, a second house or business space, was affected. The loss or erosion of physical capital had a secondary impact on livelihoods, which was compounded by the rupture in the local livelihood network following a mass population outflow. Whereas the income of locally-based businesses decreased substantially, livelihoods that operate beyond the locality remain relatively resilient. Differentiated experiences of a local change are also reflected in a range of evaluations that describe local social ambiance before and after the event. Diverse ways in which non-displaced people were affected underline that the current conceptualisation of impacts is limited to one dimension of displacement. This raises the need to adopt a more holistic and disaggregated approach to understanding the complexities of development impacts. A discussion on whether and how they can be mitigated would benefit further from such a comprehensive study.
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Johnston, Peter. « "Presences of the infinite" : J.M. Coetzee and mathematics ». Thesis, Royal Holloway, University of London, 2013. http://repository.royalholloway.ac.uk/items/644d413c-e536-f08c-f2a8-3b8e27f7dfe0/7/.
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This thesis articulates the resonances between J.M. Coetzee's lifelong engagement with mathematics and his practice as a novelist, critic, and poet. Though the critical discourse surrounding Coetzee's literary work continues to flourish, and though the basic details of his background in mathematics are now widely acknowledged, his inheritance from that background has not yet been the subject of a comprehensive and mathematically- literate account. In providing such an account, I propose that these two strands of his intellectual trajectory not only developed in parallel, but together engendered several of the characteristic qualities of his finest work. The structure of the thesis is essentially thematic, but is also broadly chronological. Chapter 1 focuses on Coetzee's poetry, charting the increasing involvement of mathematical concepts and methods in his practice and poetics between 1958 and 1979. Chapter 2 situates his master's thesis alongside archival materials from the early stages of his academic career, and thus traces the development of his philosophical interest in the migration of quantificatory metaphors into other conceptual domains. Concentrating on his doctoral thesis and a series of contemporaneous reviews, essays, and lecture notes, Chapter 3 details the calculated ambivalence with which he therein articulates, adopts, and challenges various statistical methods designed to disclose objective truth. Chapter 4 explores the thematisation of several mathematical concepts in Dusklands and In the Heart of the Country. Chapter Five considers Waiting for the Barbarians and Foe in the context provided by Coetzee's interest in the attempts of Isaac Newton to bridge the gap between natural language and the supposedly transparent language of mathematics. Finally, Chapter 6 locates in Elizabeth Costello and Diary of a Bad Year a cognitive approach to the use of mathematical concepts in ethics, politics, and aesthetics, and, by analogy, a central aspect of the challenge Coetzee's late fiction poses to the contemporary literary landscape.
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Stovold, Caroline P. « An ion-binding approach to asymmetric allylation reactions ». Thesis, University of Oxford, 2013. http://ora.ox.ac.uk/objects/uuid:1dc96ffb-f079-4b7a-847e-5d2fb792caf9.
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Ion-binding organocatalysis is an emerging field that has the potential to control the stereochemical outcome of any transformation that goes via charged intermediates. The aim of this project was to explore how this concept could be applied to an asymmetric allylation reaction. Chapter 2 of this thesis discusses anion-binding catalysis and investigates a chiral cooperative thiourea catalyst that could bind to fluoride to control allylation using an allylsilane. Optimization using a non-chiral thiourea (Schreiner’s catalyst) demonstrated that the reaction proceeded in high yield with TBAT onto an N-benzoylhydrazone. A chiral cooperative thiourea catalyst library was then synthesized but unfortunately, although the allylation using these catalysts proceeded in excellent yield, the product was isolated as the racemate (Scheme 1). Scheme 1: Anion-binding catalysis gave allylated products in high yields but gave no stereocontrol. Chapter 3 examines a chiral quaternary ammonium fluoride as an example of chiral cation-directed catalysis. We hypothesized that an allylsilane activated by fluoride would generate an allyl anion species that would associate with the chiral quaternary ammonium cation through electrostatic interactions. Extensive optimization found that the allylation reaction proceeded in good yield in chloroform at reflux with N-benzoylhydrazones. Different fluoride catalysts were prepared using an ion-exchange resin, and cinchonidine-derived catalysts performed the best. This methodology was extended to a phase-transfer catalyzed process, where solid cesium fluoride exchanged with chloride in situ, removing the need to synthesize and isolate ammonium fluoride catalysts (Scheme 2). Scheme 2: Cation-directed asymmetric allylation. In Chapter 4 cation-directed asymmetric catalysis was extended to an intramolecular allylation reaction. Substrate synthesis was attempted by cross metathesis but the reaction was capricious and yields were low. Intramolecular allylation with these materials gave promising results (Scheme 3) but a lack of material prevented optimization. Scheme 3: Intramolecular allylation results.
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Buerger, Johannes Albert. « Fast model predictive control ». Thesis, University of Oxford, 2013. http://ora.ox.ac.uk/objects/uuid:6e296415-f02c-4bc2-b171-3bee80fc081a.
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This thesis develops efficient optimization methods for Model Predictive Control (MPC) to enable its application to constrained systems with fast and uncertain dynamics. The key contribution is an active set method which exploits the parametric nature of the sequential optimization problem and is obtained from a dynamic programming formulation of the MPC problem. This method is first applied to the nominal linear MPC problem and is successively extended to linear systems with additive uncertainty and input constraints or state/input constraints. The thesis discusses both offline (projection-based) and online (active set) methods for the solution of controllability problems for linear systems with additive uncertainty. The active set method uses first-order necessary conditions for optimality to construct parametric programming regions for a particular given active set locally along a line of search in the space of feasible initial conditions. Along this line of search the homotopy of optimal solutions is exploited: a known solution at some given plant state is continuously deformed into the solution at the actual measured current plant state by performing the required active set changes whenever a boundary of a parametric programming region is crossed during the line search operation. The sequence of solutions for the finite horizon optimal control problem is therefore obtained locally for the given plant state. This method overcomes the main limitation of parametric programming methods that have been applied in the MPC context which usually require the offline precomputation of all possible regions. In contrast to this the proposed approach is an online method with very low computational demands which efficiently exploits the parametric nature of the solution and returns exact local DP solutions. The final chapter of this thesis discusses an application of robust tube-based MPC to the nonlinear MPC problem based on successive linearization.
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Davis, Harrison E. C. « An investigation of a possible non-neuronal cholinergic system in the vasculature ». Thesis, University of Oxford, 2015. https://ora.ox.ac.uk/objects/uuid:9249c66f-f074-41ce-83a4-029d654d5124.
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Vascular endothelial cells express muscarinic acetylcholine receptors, which lead to NO- and endothelium derived hyperpolarization responses that constitute major pathways for vasodilation. As evidence suggests that perivascular nerves may not represent a viable source of innervating ACh, we investigated whether suggestions of a 'non-neuronal cholinergic system' within the vasculature might act as a source of ACh that is able to influence the endothelium. Rat mesenteric arteries were cut open and held as an en-face preparation with the endothelial cell (EC) layer exposed to measure EC [Ca2+]i. Furthermore we present the first example of EC tubes isolated from rat mesenteric arteries, used to measure EC [Ca2+]i. Immunohistochemistry was performed on intact arteries to demonstrate localization of important cholinergic proteins. Direct application of rat whole blood induced increased Ca2+ activity in ECs that did not appear to rely on shear stress or other mechanical interaction of the blood with the endothelial cells. This response, shown to rely on IP3 mediated Ca2+ release, was attenuated by the muscarinic antagonist atropine; it was concluded that blood contains or induces the release of non-neuronal ACh. The localization of the ACh synthesizing protein, choline acetyltransferase by immunohistochemistry provides evidence for a source of ACh originating within the endothelium. In accordance with this, the blocker of high affinity choline uptake, hemicholinium-3, had a significant effect in reversing choline potentiated responses in ECs. Taken together, we proposed that ACh is released potentially via organic cation transporter proteins located in the endothelium, upon stimulation by blood in response to an as yet undetermined signal. The ability to influence EC Ca2+ highlights a role for blood in the local control of these cells and the data presented suggest ACh produced locally may provide physiological relevance by exerting influence on endothelial M3 muscarinic acetylcholine receptors.
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Ruckli, Beatrix. « The meaning of creative activities in the lives of people in remission from mental illness ». Thesis, University of Brighton, 2016. https://research.brighton.ac.uk/en/studentTheses/fc01d70f-f071-46fa-9d19-a64c590cb6bf.
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Traditionally, creative activities have been used in occupational therapy practice as an intervention with people who have a mental illness. Recent research has explored engagement in creative activities with people living with disabilities, mental illness, retired people and people with cognitive impairment. The findings centred on positive emotions, increase in self-confidence and respite from worrying thoughts. Anecdotal evidence from local occupational therapy practitioners and arts organisations suggested that people in remission of mental illness seemed to use creative activities in their daily lives as a way to keep well, but deeper understanding was missing about this. The first aim of this study was to gain a deeper understanding of the phenomenon of voluntary participation in creative activities by people in remission of mental illness. The second aim was to explore and provide evidence of any relationship between well-being and creative activities as it was perceived by the participants. The research utilised a hermeneutic phenomenological approach. Qualitative data were collected through interviews with participants, transcribed verbatim and analysed within the hermeneutic tradition. Ten participants volunteered and were recruited by mental health NHS staff in central England. All participants had a diagnosis of a mental illness but were in remission from between six months and seven years at the time of the interviews. The data were analysed via my own interpretation of Cohen, Kahn and Steeves’ (2000) approach to hermeneutic phenomenological data analysis. The findings revealed that for all participants, engagement in their chosen creative activity evoked enjoyment and was of particular personal significance and meaning. Their subjective experiences highlighted the possible therapeutic potential of creative occupation, in particular, temporary mental relief from self-referential thoughts through deep immersion into the creative process. Deep engagement in creative occupation encompassed different types of optimal experience and might have a soothing effect on the Default Mode Network. The deliberate engagement in creative activities supports Wilcock’s theory of the use of occupation for self-restoration and keeping healthy. Additionally, the real contact with people and places facilitated a more active lifestyle which impacted also positively on the participants’ sense of well-being. The findings of the study are discussed from an occupational science perspective to extend our understanding of the solitary and group nature and effects of participation in creative activities.
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Emanuele, Sozzi. « Low-cost physico-chemical disinfection of human excreta in emergency settings ». Thesis, University of Brighton, 2016. https://research.brighton.ac.uk/en/studentTheses/1d15b231-f0bc-4251-bf5c-7d7912073d84.
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The operation of a health-care facility, such as a cholera or Ebola treatment centre in an emergency setting, results in the production of pathogen-laden wastewaters that may potentially lead to onward transmission of the disease. The research presented here outlines the results of field and laboratory studies devised to inform the design and operation of a novel full-scale treatment protocol to disinfect pathogen-laden hospital wastewaters in situ, thereby eliminating the need for potentially hazardous road haulage and disposal of human excreta or wastewater to poorly-managed waste facilities. The approach investigated has the potential to provide an effective barrier to disease transmission by means of a novel but simple sanitary intervention. During Phase I of this research, a fieldwork study in Haiti focused on the design and operation, at short notice and within a disaster setting, of a new treatment technology that aimed to obviate the transport of untreated human excreta from emergency cholera treatment centres (CTC) to poorly-managed waste facilities. The results of this fieldwork period were validated and further optimised during Phase II: a detailed laboratory-based study in the UK that assessed the performance of the novel treatment technology in order to improve its efficacy. The performance of two physico-chemical protocols was monitored, first in the field (Port-au-Prince, Haiti), by means of both bench-scale and full-scale batch treatment of real highly-contaminated faecal waste from a cholera treatment centre (Phase I), and subsequently during more detailed laboratory studies (Phase II) using a ‘faecal-waste matrix’ that was created by mixing various municipal wastewaters and sludges in a proportion that aimed to mimic the composition of wastewaters produced at health-care facilities in emergency settings. The two investigated protocols achieved coagulation/flocculation and disinfection by exposure to high– or low–pH environments, using thermotolerant coliforms, intestinal enterococci, and somatic coliphages as indices of disinfection efficacy, and several physico-chemical parameters as indicators of treatment performance. In the high–pH treatment protocol, the addition of hydrated lime resulted in wastewater disinfection and coagulation/flocculation of suspended solids. In the low-pH treatment, disinfection (and partial colloidal destabilization followed by sedimentation) was achieved by the addition of hydrochloric acid, followed by pH neutralisation. A potential further step in this 4 second protocol was the coagulation/flocculation of suspended solids using aluminium sulphate. During Phase II, removal rates achieved for the high pH treatment protocol, in terms of physico-chemical parameters, were: COD > 80%; suspended solids > 85%; turbidity > 85%. Removal rates in terms of microbiological parameters were: thermotolerant coliforms > 5 Log10, intestinal enterococci >2 Log10 and somatic coliphage > 2 Log10. Removal rates achieved for the low-pH treatment protocol in terms of physico-chemical and microbiological parameters were: COD > 80%; thermotolerant coliforms between 0.2 and 1.2 Log10, with a mean removal of 0.75 Log10 and > 3 Log10 removal for intestinal enterococci. The removal of somatic coliphage was in excess of 4 Log10. The quantity and density of the sedimented sludge and several other physicochemical parameters (such as total nitrogen, total phosphorous, ammonia and ammonium, etc.) for the analysis of the supernatant were also monitored. This study represented the first known successful attempt to disinfect wastewater in a disease outbreak setting without resorting to the alternative, untested, approach of ‘super-chlorination’ which, it has been suggested, may not consistently achieve adequate disinfection. In addition, a basic costs analysis demonstrated significant savings in the use of reagent compared with super-chlorination. The approach to sanitation for cholera treatment centres and other disease outbreak settings presented here offers a timely response to a UN call for in situ disinfection of wastewaters generated in such emergencies. Further applications of the method to other emergency settings have been actively explored in discussion with the World Health Organization (WHO) in response to the ongoing Ebola outbreak in West Africa, and with the UK-based non-governmental organization (NGO) Oxfam.
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D'Cruze, Neil. « Conserving amphibian and reptile diversity in north Madagascar : contributions from baseline herpetological survey work ». Thesis, Oxford Brookes University, 2011. http://radar.brookes.ac.uk/radar/items/9ec5ad4d-f0ec-31e4-c23d-ce4e60a3aa89/1.
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Madagascar has long been recognized as one of the world’s priority global hotspots for biodiversity conservation. Its herpetofauna, in particular, is extremely species-rich and diverse with high levels of endemism. By far the most important threat to its continued survival is the relentless destruction of its primary habitats. Socioeconomic factors in combination with particular aspects of Malagasy culture have led to the exploitation of natural resources which have already had an impact at a national level. Conservation strategies are in place to protect this unique fauna. However, in practice they are constrained in part by a lack of information regarding the distribution, abundance, natural history, and habitat requirements of threatened species. Accessible information, generated by baseline herpetological surveys, is particularly lacking for several key regions such as the northern province of Antsiranana. The first study in this research programme represents a review of modern herpetological survey work (1994-2007) in Madagascar and serves to highlight why Antsiranana was selected as a region of focus. The following three studies are focused on baseline herpetological survey work that was conducted in several key sites of conservation importance throughout the province. A further three studies provide an account of six species (previously unknown to science) that were discovered and described as a result of this survey work. The remaining two studies provide an insight into the impact that anthropogenic habitat alteration is having on lizard abundance, diversity and community composition in the extreme north of this island. Overall, these studies represent an advancement of the knowledge regarding a threatened herpetofauna. They elucidate a number of issues pertaining to broader questions of conservation biology in Madagascar that have been traditionally confounded by a lack of evidence.
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Lefevre, Fabien. « Caractérisation de structures du type plaque par ondes guidées générées et détectées par laser ». Valenciennes, 2010. http://ged.univ-valenciennes.fr/nuxeo/site/esupversions/24980ba6-f06c-4c75-988a-16e1228d2e42.
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La réalisation de couches minces déposées sur substrats est très recherchée dans de nombreuses applications. C'est le cas par exemple des pièces nickelées destinées à des dispositifs à hautes performances techniques, où une couche anti-corrosion est déposée a n d'améliorer leur imperméabilité. L'utilisation de ces structures du type couche sur substrat étant grandissante, on comprend dès lors l'importance de disposer de moyens non destructifs permettant de les contrôler et de les caractériser. Dans ce travail, l'objectif a été de mettre à pro t les ondes acoustiques guidées pour le contrôle et la caractérisation de structures du type plaque. Pour la génération et la détection de ces ondes guidées, la technique laser-ultrasons a été privilégiée. C'est une méthode large bande et sans contact permettant d'éviter l'utilisation d'un milieu de couplage ou tout contact direct avec la structure et pouvant s'adapter à des géométries complexes. Pour tirer pro t au maximum de l'utilisation de cette technique, des réseaux de neurones lui ont été associés a n de résoudre le problème inverse posé par les ondes de plaque. Une méthode de caractérisation originale, e cace et polyvalente a ainsi été mise en oeuvre, permettant de déterminer les propriétés géométriques et/ou mécaniques de plaques simples ou de structures à couches. Des structures composées de silicium ont plus particulièrement été étudiées par le biais de cette méthode. Des simulations éléments nis, ainsi que des études sur certains défauts présents dans les couches minces, comme l'adhérence, sont présentéesThe deposition of thin layers on substrates is more and more required in many applications. For example, to reach high technical performance, bumpers or other parts are nickeled to improve their impermeability and resistance. Another example in microelectronics is the realization of transistors found in LCDs where they are associated with each pixel. The use of these layer/substrate structures is growing, so the importance of having non-destructive techniques to monitor and characterize them is well understood. The point in using ultrasonic waves for non-destructive testing and evaluation of various materials and structures is well known. In this work, the aim was to use guided waves to monitor and to characterize plaque-like structures. The main advantage of using these modes lies in their ability to test very large areas and inaccessible structures. For the generation and detection of guided waves, the laser ultrasonics technique was preferred. It is a broadband and non contact method which doesn't imply the use of coupling medium and which can be adapted to complex geometries. To take full advantage of this technique, it has been combined with neural networks in order to solve the inverse problem posed by the propagation of guided waves. As a result, an original, e cient and polyvalent characterization method has been obtained, which allowed us to determine the geometric properties and / or the elastic parameters of di erent plate-like structures. Structures made of silicon have been studied with this method. Finite element simulations and studies concerning the in uence of defects, including adhesion, on the waves propagation are also presented
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Gobin, Damien. « Étude de problèmes de diffusion inverse à énergie fixée pour des variétés asymptotiquement hyperboliques ». Nantes, 2016. http://archive.bu.univ-nantes.fr/pollux/show.action?id=19e4187d-f072-4f00-a81c-f636386c7d24.
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On étudie des problèmes de diffusion inverse à énergie fixée pour différents types de géométries ayant plus ou moins de symétries. On commence par obtenir un résultat de diffusion inverse local à énergie fixée pour l’équation de Dirac sans masse et sans charge sur des variétés asymptotiquement hyperboliques et à symétrie sphérique. Dans un second chapitre on s’intéresse aux trous noirs de type Reissner-Nordström-de Sitter qui sont des solutions à symétrie sphérique et électriquement chargées de l’équation d’Einstein. On obtient alors un résultat de diffusion inverse à énergie fixée pour l’équation de Dirac massive et chargée. Enfin, on s’intéresse à des variétés de Stäckel de dimension trois ayant la topologie d’un cylindre torique, satisfaisant la condition de Robertson et munies d’une structure asymptotiquement hyperbolique. Sur ces variétés on utilise la théorie de séparation des variables pour l’équation de Helmholtz et une version multivariable de la méthode de Complexification du Moment Angulaire afin d’obtenir un résultat de diffusion inverse à énergie fixéeWe study inverse scattering problems at fixed energy for different geometries with more or less symmetries. First, we obtain a local inverse scattering result at fixed energy for the massless and chargeless Dirac equation on asymptotically hyperbolic manifolds with spherical symmetry. In a second chapter, we are interested in Reissner-Nordström-de Sitter black holes which are spherically symmetric and electrically charged solutions of the Einstein equation. We then obtain an inverse scattering result at fixed energy for the massive and charged Dirac equation. Finally, we are interested in Stäckel manifolds of dimension three with the topology of a toric cylinder, satisfying the Robertson condition and endowed with an asymptotically hyperbolic structure. On these manifolds we use the variable separation theory for the Helmholtz equation and a multivariable version of the method of Complexification of the Angular Momentum in order to obtain an inverse scattering result at fixed energy
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Neyrat, Mathieu. « Contribution à l’étude de G. P. R. (Ground Penetrating Radar) multicapteurs : Méthodes directes et inverses en temporel ». Limoges, 2009. https://aurore.unilim.fr/theses/nxfile/default/a81b4d3c-f079-405b-88a2-1f087d9726f1/blobholder:0/2009LIMO4003.pdf.
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Les radars à sondage de sol aussi appelés GPR (Ground Penetrating Radar) jouent un rôle important pour la prospection non destructive dans des domaines très variés. Ce travail propose une étude théorique de ce type de radar dans une configuration multicapteur. Dans un première partie, les lois fondamentales de l’électromagnétisme ainsi que le principe de fonctionnement d’un radar GPR sont présentés. Une méthode numérique permettant la modélisation rapide d’une scène réaliste et le calcul de B-scan est décrite. Cette méthode basée sur la FDTD (Finite Difference Time Domain) a permis de tester différentes configurations de radars multicapteurs et d’en montrer leur apport. La dernière partie propose deux méthodes inverses dans le domaine temporel. La méthode de retournement temporel et la méthode de focalisation de phase s'avèrent bien adaptées à la localisation d’objets à partir d’enregistrements provenant de radars multicapteursGround Penetrating Radars (G. P. R. ) contribute in non-destructive survey in various domains. This work deals with a study of GPR in multisensor configuration. In a first part, the fundamental laws of electromagnetism and the radar principle are presented. A numerical method for fast modeling of realistic scenes and B-scan calculation is described. This method based on the FDTD (Finite Difference Time Domain) allowed to test various configurations of multisensor radar and to show their contribution. The final section proposes two inverse methods in time domain. The reverse time method and the phase shift method are well suited to the location of objects from multisensor radar records
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Thomas, Robyn. « Appraisal in the gendered organisation : the experience of women academics ». Thesis, University of South Wales, 1997. https://pure.southwales.ac.uk/en/studentthesis/appraisal-in-the-gendered-organisation(6c27a71b-f07a-46ee-9354-c5e0fd992d8e).html.
Texte intégralRésumé :
This thesis investigates women academics' experiences of the gendered university culture, during a period of rapid change in the management of higher education and the academic profession. The research draws on a Foucauldian feminist methodology to understand how, and in what ways, the dominant discourses of the university culture constitute women academics' identities. In particular, the research questions the nature of the gender relations emerging as a result of the introduction of the discourses of 'new public management'. The research examines the ways in which these new discourses are promoted through a range of disciplinary technologies, including academic appraisal, and the impact this has on women academics' professional roles and identities. The empirical work is based on three university case studies, from both the 'old' and 'new' university sectors. In each case study, the women academics tell of their experiences of the gendered university culture, and their perceptions of the appraisal process. The findings suggest that the recent changes in the management of universities have reinforced and strengthened the masculine discourses of the gendered academy. The opportunities for women to exploit the discursive spaces arising from the recent unseating of the traditional discourses of the academy have been marginal. Through the adoption of a Foucauldian feminist methodology, this research has enabled women academics to have a voice in the shaping of knowledge about university organisations and management. In doing so, the research contributes to the understanding of gendered university cultures and the constitution of individual subjectivities, as well as, in the wider context, the gendered nature of organisations and organisational theory.
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Kenny, Daryl Evan. « A force for good : exploring the future of non-crime policing ». Thesis, University of Portsmouth, 2016. https://researchportal.port.ac.uk/portal/en/theses/a-force-for-good(78f7bf16-f077-4044-b3e0-2552d5bd6d6a).html.
Texte intégralRésumé :
Crime is promoted by the government as being the primary task of the police, yet such a focus marginalizes the extraordinary prominence and relevance of many non-crime policing activities. This research highlights the breadth and complexity of those duties, filling a gap in the literature by exploring the possible future of non-crime policing. The research draws on extensive literary sources and utilizes quantitative data covering eight years of public calls made to the Staffordshire Police. The research includes qualitative data obtained from thirteen semi-structured interviews with individuals who have extensive policing experience. The research found that public demand for policing declined over the reviewed period, with staffing levels in Staffordshire dropping and government funding falling drastically. There were marked increases in ‘concern for safety’ incidents, ‘suicides’ and cases involving individuals suffering mental health crises. The research explored policing from a historical perspective drawing on European and British history, ancient and modern, in order to help shine a light on prospective future developments. The research suggested that policing is torn between those who feel that non-crime matters are important and those who think that policing should be largely crime-focused. Concerns were raised about the on going politicization of policing, the extended police hierarchy and the impact of neo-liberalism on non-crime demand. Non-crime policing appears to be moving incrementally towards pluralization and privatisation, though it could also help initiate a more unified, internationalized policing service built around human rights. All futures remain open and it is up to all of us to decide what that future will ultimately be.
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Schwandner-Sievers, Stephanie. « Invoking a culture - deploying a past : Albanian identifications and translocal encounters ». Thesis, University of Roehampton, 2012. https://pure.roehampton.ac.uk/portal/en/studentthesis/invoking-a-culture---deploying-a-past(1c49cdc1-f03c-4c19-aa46-3e75b0c4938b).html.
Texte intégralRésumé :
This thesis traces internal and external identity constructions of Albanians through recourse to specific local Albanian pasts in post-socialist, including post-war, translocal and globalised realms of encounters. In this the main (but not exclusive) focus is on the role of traditionalist signifiers, their historical legacy and the ways in which these have informed perceptions of Albanianness both of themselves and by others, sometimes in unexpected complicity. My publications, as assembled in this thesis, demonstrate that identity-constitutive recourse to specific pasts, particularly to tropes of pre-communist north-Albanian customary law, frequently and stereotypically subsumed under the Ottoman term, kanun, have shaped and framed not just ideas about Albanianness but also served to delineate concrete social relations and relations of power, to justify social and political exclusion and inclusion as well as practices of resistance and subversion both between and among Albanians as well as with non-Albanians alike. Such identity constructions in traditionalist terms of Self or Other, respectively, as observed during the last twenty years in multi-sited ethnography, emerged from and were negotiated at, interconnected arenas of power where people as well as ideas about Albanians meet and matter still today with real social and political consequences in practice.
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Crow, Megan. « Investigating histone deacetylase four in sensory neurons ». Thesis, King's College London (University of London), 2014. https://kclpure.kcl.ac.uk/portal/en/theses/investigating-histone-deacetylase-four-in-sensory-neurons(b1b9b716-f070-48a8-b380-f79f113d4f86).html.
Texte intégralRésumé :
Histone deacetylase inhibitors are analgesic in preclinical pain models but the contribution of specific histone deacetylases (HDACs) to pain states remains unclear. HDAC4 is a transcriptional co-repressor that has previously been linked to aberrant nociception and synaptic plasticity. The aim of this project was to investigate the role of HDAC4 in vivo using the Cre-loxP system to conditionally delete HDAC4 from primary sensory neurons and characterize transcriptional and behavioural outcomes in models of pain and peripheral nerve regeneration. To do this I established two novel HDAC4 conditional knockout strains that enabled investigation of HDAC4 in both sensory neuron development and in adult sensory processing. In both strains, loss of HDAC4 was associated with altered expression of the gene encoding the transient receptor potential cation channel member A1 (Trpa1) and the voltage-gated calcium channel subunit α2δ-1 (Cacna2d1) in naïve ganglia. Bioinformatics analysis indicated that HDAC4 may bind Cacna2d1 directly. Furthermore, across many injury paradigms I found that HDAC4 conditional knockouts expressed lower levels of calcitonin-related polypeptide alpha (Calca) and the gene encoding the high-affinity nerve growth factor receptor (Ntrk1). While peripheral expression of HDAC4 was not required for sensory neuron differentiation, peripheral nerve regeneration or for the development of mechanical hypersensitivity in neuropathic pain models, I found highly reproducible and significant attenuation of thermal hypersensitivity in models of chronic inflammation. This was associated with significantly reduced mRNA expression of the transient receptor potential cation channel member V1 (Trpv1) and reduced capsaicin sensitivity in vitro, possibly as a result of aberrant nerve growth factor signaling. HDAC inhibitors and other drugs that target chromatin modifying and transcriptional regulatory proteins are already being used clinically to treat cancer. Work to characterize the function of these molecules in diverse systems will provide a rational basis for the broader application of these therapies.
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Makoelle, Tsediso Michael. « Exploring teaching practices that are effective in promoting inclusion in South African secondary schools ». Thesis, University of Manchester, 2013. https://www.research.manchester.ac.uk/portal/en/theses/exploring-teaching-practices-that-are-effectivein-promoting-inclusion-in-south-africansecondary-schools(7b2127b0-f07f-4c9a-9708-95c37b078bdf).html.
Texte intégralRésumé :
Prior to the advent of the new democratic political dispensation in 1994, South African education had laboured under racially motivated discriminatory practices of active exclusion of the majority of learners. The authoritarian system located educational problems in the perceived deficiencies of the learner rather than in the repressive, top-down, non-participative, unreflective and uninclusive practices of the prevailing educational orthodoxy of the time. After 1994, the broader reconceptualisation of South African education sought to redress the imbalances of the past by creating equal opportunities for all learners, irrespective of race or creed. However, the difficult conundrum was how such a complex systemic change could be driven by teachers who had not only been trained in a heavily segregated educational system but formed part of it. Therefore, the aim of the thesis was to determine how teachers conceptualised inclusive teaching, explore the teaching practices that were believed to be effective in promoting inclusion in the South African secondary classrooms, and determine how they could be developed. The two-dimensional research study firstly took the form of a qualitative collaborative action research project conducted with a team of fifteen teachers at a single South African secondary school. The project was non-positivistic, critical, emancipatory and allowed the participants jointly to define the constructs of inclusive education, inclusive teaching and inclusive class; to identify practices of inclusion through observation; to adopt other practices in their classes; to determine the effect of such practices on inclusive teaching and learning; and finally to draw conclusions about the specific practices that were clearly effective in the context of their school. Secondly, an inductive analytical framework was used by the researcher to determine the theoretical contribution the study would make to the notion of developing inclusive teaching practices and determining the way this could be achieved within the South African school context. Data were collected through a series of meetings, participant observations, focus-group interviews, and one-on-one semi-structured interviews during the action-research stages of planning, action and reflection. Limitations were the teacher-researchers' lack of experience in conducting research and the limited time the research team had to complete the research tasks. The findings indicate that, at the time of the research, the conceptualisations of inclusive teaching and inclusive pedagogy were varied and continued to be influenced by the former special-needs education system. Moreover, the findings show that, while the inclusive practices identified by the teachers in this study are popular in the international literature, they need to be contextualised in and made relevant to the South African situation. However, it is clear that the teachers' experience of participating in the action-research process had raised their awareness of the importance of inclusive teaching, promoted a sense of emancipation, and held out the prospect of successful and possibly lasting change. These findings clearly imply that the reconceptualisation of inclusive pedagogy should always take place within a specific context, and that South African teachers in particular should form communities of inquiry to reflect on and develop their inclusive practices. The study has captured the essence of inclusion within the South African school context and has identified areas that need further research, for example the impact of different cultural beliefs on both teachers and learners in relation to inclusion. In conclusion, the study has demonstrated the unique contribution of action research in promoting continuous reflection, revision and intervention as indispensable procedures in the process of improving inclusive teaching and learning.
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Monger, David. « The National War Aims Committee and British patriotism during the First World War ». Thesis, King's College London (University of London), 2009. https://kclpure.kcl.ac.uk/portal/en/theses/the-national-war-aims-committee-and-british-patriotism-during-the-first-world-war(95dde034-f075-4b5f-a0d4-4d9179a8e6d5).html.
Texte intégralRésumé :
This thesis discusses the National War Aims Committee (NWAC), a cross-party, Treasury-funded Parliamentary organisation established in mid-1917 to conduct domestic propaganda. The thesis provides the most comprehensive examination of its organisational structure, expanding upon and correcting existing historical treatments, and demonstrating that it was a more significant element of British wartime society than previously assumed. It also provides much greater discussion of the NWAC's reception by Parliament, the press and the public. The thesis provides extensive analysis of the representation of patriotism in NWAC propaganda. This exceeds existing work, considering all its printed propaganda, but also reports of NWAC events in over a hundred newspapers in thirty localities. This detailed analysis suggests that NWAC propagandists retained many familiar themes of pre-war patriotism and national identity. This observation counters assumptions that pre-war patriotism was nullified by the mass casualties suffered by patriotic volunteers. However, I argue that while basic patriotic themes remained recognisable, NWAC propaganda reconfigured them in a narrative reflective of the experience of war-weary civilians. The propaganda generally revolved around a core idea of duty, supplemented by one or more contextual elements which demonstrated its necessity. I suggest several categories of interactive and interdependent `presentational patriotisms' used by propagandists to influence civilian attitudes. Further, I demonstrate that each category is discernible more widely in pre-war settings, suggesting that, while the model narrative might vary in different situations, the general history of British patriotism might benefit from applying the evidence of my thesis to other examples. I challenge the significance of the familiar `otherness' paradigm of national identity, suggesting that the recognition of difference was only part of the patriotic narrative supplied by the NWAC. Further, my analysis is particularly concerned with the interactions between local, national and supranational sources of identity, often overlooked or under-examined by historians
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Howard, Louise A. « Effects of traumatic experiences on information processing in patients with mental health problems ». Thesis, Bangor University, 2005. https://research.bangor.ac.uk/portal/en/theses/effects-of-traumatic-experiences-on-information-processing-in-patients-with-mental-health-problems(fa3005a4-f0dc-44cd-a44b-1255d3a91777).html.
Texte intégralRésumé :
All human experiences have an effect on the brain, and in the form of memories and cognitive biases, affect the response of the individual to future events. When people experience traumatic events the brain is sometimes impacted in extreme ways, with major consequences for the individual in the form of psychiatric illness. This study is concerned with examining the way in which the prior experience of traumatic events affects the processing of simple stimuli under experimental conditions, in order to understand better the types of cognitive biases involved in psychiatric illnesses. The study used a well-established computerized test of selective attention, inhibition of return (IOR), and a newer task involving facial expressions and gaze cues. A review of the use of the IOR paradigm in different adult psychiatric disorders was conducted in order to aid interpretation of the findings. The mental health status of the participants was described by use of a number of standardized questionnaires. Participants were people in contact with Adult Mental Health services who had experienced trauma, including those with Posttraumatic Stress Disorder (PTSD), Psychosis and other psychiatric diagnoses. Results were compared with a healthy control group. Despite small sample sizes and heterogeneity within the groups, the study indicated that significant trauma can be associated with different types of mental health problem, and that different mental health problems are associated with different types of cognitive processing difficulty. The Psychosis group showed a lack of inhibitory processing, which is likely to be associated with increased distractibility, and, for example, lack of the ability to follow a train of thought. This is different from the distractibility seen in PTSD, which can be characterized as a tendency for attention to be captured by a salient stimulus without appropriate subsequent disengagement.
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Ive, Jeremy. « A critically comparative Kuyperian analysis and a trinitarian, 'perichoretic' reconstruction of the Reformational philosophies of Dirk H.Th. Vollenhoven and Herman Dooyeweerd ». Thesis, King's College London (University of London), 2012. https://kclpure.kcl.ac.uk/portal/en/theses/a-critically-comparative-kuyperian-analysis-and-a-trinitarian-perichoretic-reconstruction-of-the-reformational-philosophies-of-dirk-hth-vollenhoven-and-herman-dooyeweerd(fb743439-f03c-4cac-a74e-4c95d83efc44).html.
Texte intégralRésumé :
This is a critically constructive study of the systematic thought of two ’Reformational’ philosophers Dirk H.Th. Vollenhoven (1892-1978) and Herman Dooyeweerd (1894-1977) within the contours of the Reformational vision which they both inherited from the founder of the modern Reformational tradition, Abraham Kuyper (1837-1920). While exploratory work has been done in this area, a full systematic comparison is undertaken here for the first time. Elements in the thought of the two philosophers which may seem to be at variance will be shown to be complementary or at least capable of correction by the thought of the other. This will be done by returning to the trinitarian basis of the Kuyperian vision, and more specifically, the notion of ’perichoresis’ which affirms at once the distinctiveness of the work of each of the triune Persons and the harmony of their joint achievement. It will be argued that this trinitarian grounding and ’perichoretic’ reconstruction of the thought of the two philosophers provides a more fully-rounded Reformational account - one with a greater overall coherence than the work of either provides on its own - resulting in a philosophy true to the vision which they together inherited, offering a systematic framework serviceable alike for inter-disciplinary work in the contemporary academy, and for Christian engagement in the public square.
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Doummar, Joanna Jean. « Identification of indicator parameters for the quantitative assessment of vulnerability in karst aquifers ». Doctoral thesis, 2012. http://hdl.handle.net/11858/00-1735-0000-000D-F07C-8.
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Höcht, Anna. « Quantifizierung der Freisetzung bakterieller DNA in Modellen experimenteller bakterieller Meningitis ». Doctoral thesis, 2012. http://hdl.handle.net/11858/00-1735-0000-000D-F01C-D.
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Schneider, Markus. « Ein Leben mit Schmerzen - Formen der psychosozialen Bewältigung bei Morbus-Sudeck-Patienten ». Doctoral thesis, 2012. http://hdl.handle.net/11858/00-1735-0000-000D-F02C-9.
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Lankeit, Henrike Katharina. « Radioimmuntherapie bei diffus großzelligen B-Zell-Lymphomen ». Doctoral thesis, 2012. http://hdl.handle.net/11858/00-1735-0000-000D-F03C-5.
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Kywe, Tin Zar. « Habitat Suitability Modeling for Tiger (Panthera tigris) in the Hukaung Valley Tiger Reserve, Northern Myanmar ». Doctoral thesis, 2012. http://hdl.handle.net/11858/00-1735-0000-000D-F05C-E.
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Müller, Robert. « Policy options to reduce deforestation in the Bolivian lowlands based on spatial modeling of land use change ». Doctoral thesis, 2012. http://hdl.handle.net/11858/00-1735-0000-000D-F07E-4.
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Koch, Sebastian. « Natural Resource Use Conflicts in Indonesia : A Challenge for Sustainable Development and Education for Sustainable Development ». Doctoral thesis, 2012. http://hdl.handle.net/11858/00-1735-0000-000D-F079-E.
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Morales, Demarco Manuela. « Mineralogical, Petrophysical and Economical Characterization of the Dimensional Stones of Uruguay ; Implications for Deposit Exploration ». Doctoral thesis, 2012. http://hdl.handle.net/11858/00-1735-0000-000D-F07A-C.
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Tum, Markus. « Modelling and validation of agricultural and forest biomass potentials for Germany and Austria ». Doctoral thesis, 2012. http://hdl.handle.net/11858/00-1735-0000-000D-F07B-A.
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Köhler, Stefan. « Bestandes- und Freilandnährstoffeinträge in Zentralsulawesi (Indonesien) ». Doctoral thesis, 2012. http://hdl.handle.net/11858/00-1735-0000-000D-F07D-6.
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Kellner, Ansgar. « A Multi-objective Ant Colony Optimisation-based Routing Approach for Wireless Sensor Networks Incorporating Trust ». Doctoral thesis, 2012. http://hdl.handle.net/11858/00-1735-0000-000D-F06C-A.
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Hameed, Sufian. « Leveraging Email based Social Networks to Prevent Spam : Framework, System Design and Evaluation ». Doctoral thesis, 2012. http://hdl.handle.net/11858/00-1735-0000-000D-F070-F.
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Ober, Ulrike. « Genomic Prediction for Quantitative Traits : Using Kernel Methods and Whole Genome Sequence Based Approaches ». Doctoral thesis, 2012. http://hdl.handle.net/11858/00-1735-0000-000D-F071-D.
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Aksoy, Eren Erdal. « Semantic analysis of image sequences using computer vision methods ». Doctoral thesis, 2012. http://hdl.handle.net/11858/00-1735-0000-000D-F072-B.
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Abramov, Alexey. « Compression of visual data into symbol-like descriptors in terms of a cognitive real-time vision system ». Doctoral thesis, 2012. http://hdl.handle.net/11858/00-1735-0000-000D-F073-9.
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Palm, Marc. « Explicit GL(2) trac formulas and uniform, mixed Weyl laws ». Doctoral thesis, 2012. http://hdl.handle.net/11858/00-1735-0000-000D-F074-7.
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Sohns, Melanie. « The Empirical Hierarchical Bayes Approach for Pathway Integration and Gene-Environment Interactions in Genome-Wide Association Studies ». Doctoral thesis, 2012. http://hdl.handle.net/11858/00-1735-0000-000D-F075-5.
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Taheri, Somayeh. « Anonymity and Privacy in Wireless Mobile Ad Hoc Networks ». Doctoral thesis, 2011. http://hdl.handle.net/11858/00-1735-0000-000D-F076-3.
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Dong, Zhijie. « Prediction of Protein-Protein Interaction Sites with Conditional Random Fields ». Doctoral thesis, 2012. http://hdl.handle.net/11858/00-1735-0000-000D-F077-1.
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Memarmoshrefi, Parisa. « A Bio-Inspired Autonomous Authentication Mechanism in Mobile Ad Hoc Networks ». Doctoral thesis, 2012. http://hdl.handle.net/11858/00-1735-0000-000D-F078-0.
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Christoph, Johannes. « Die Herzfunktion während milder Hypothermie bei anästhesierten Schweinen : gesteigerte Inotropie auf Kosten einer diastolischen Dysfunktion ». Doctoral thesis, 2012. http://hdl.handle.net/11858/00-1735-0000-000D-F07F-2.
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Guindon, Stefan. « A Top Quark Mass Measurement Using the R32 Stabilized Variable with the ATLAS Detector ». Doctoral thesis, 2012. http://hdl.handle.net/11858/00-1735-0000-000D-F08C-4.
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Thomä, Jörg. « Kleine und mittlere Unternehmen mit Besonderheiten ? – Beiträge zur Mittelstandsforschung an den Beispielen von Innovation und Konjunktur ». Doctoral thesis, 2012. http://hdl.handle.net/11858/00-1735-0000-000D-F09C-F.
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Arias, Elkin. « Aufbau von Handlungswissen und Kompetenzlernen bei Sportspielen, ein didaktisches Modell der Spielhandlungskompetenzen ». Doctoral thesis, 2012. http://hdl.handle.net/11858/00-1735-0000-000D-F0AC-B.
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Wittnam, Jessica L. « The contribution of N-terminally modified amyloid beta to the etiology of Alzheimer's disease ». Doctoral thesis, 2012. http://hdl.handle.net/11858/00-1735-0000-000D-F0BC-7.
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Iraheta, Raul Emilio. « Sec1p/Munc18 (SM) proteins and their role in regulating secretion in Saccharomyces cerevisiae and Caenorhabditis elegans a comparative approach ». Doctoral thesis, 2012. http://hdl.handle.net/11858/00-1735-0000-000D-F0CC-3.
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Kittelmann, Maike. « Synaptic Ultrastructure and Regulation of Synaptic Transmission in Caenorhabditis elegans ». Doctoral thesis, 2012. http://hdl.handle.net/11858/00-1735-0000-000D-F0C7-D.
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